WO2014121391A1 - Expandable suspension systems for intraocular lenses - Google Patents

Expandable suspension systems for intraocular lenses Download PDF

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Publication number
WO2014121391A1
WO2014121391A1 PCT/CA2014/050074 CA2014050074W WO2014121391A1 WO 2014121391 A1 WO2014121391 A1 WO 2014121391A1 CA 2014050074 W CA2014050074 W CA 2014050074W WO 2014121391 A1 WO2014121391 A1 WO 2014121391A1
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WO
WIPO (PCT)
Prior art keywords
cavities
haptic
expandable
walls
hollow
Prior art date
Application number
PCT/CA2014/050074
Other languages
French (fr)
Inventor
Garth T. Webb
Original Assignee
Ventura Holdings Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ventura Holdings Ltd. filed Critical Ventura Holdings Ltd.
Publication of WO2014121391A1 publication Critical patent/WO2014121391A1/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16Intraocular lenses
    • A61F2/1613Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16Intraocular lenses
    • A61F2/1601Lens body having features to facilitate aqueous fluid flow across the intraocular lens, e.g. for pressure equalization or nutrient delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16Intraocular lenses
    • A61F2/1613Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A61F2/1624Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus having adjustable focus; power activated variable focus means, e.g. mechanically or electrically by the ciliary muscle or from the outside
    • A61F2/1635Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus having adjustable focus; power activated variable focus means, e.g. mechanically or electrically by the ciliary muscle or from the outside for changing shape
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16Intraocular lenses
    • A61F2002/1681Intraocular lenses having supporting structure for lens, e.g. haptics
    • A61F2002/1689Intraocular lenses having supporting structure for lens, e.g. haptics having plate-haptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0014Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0061Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof swellable

Definitions

  • the present invention relates to the applicant's inflatable lens/lens retainer as
  • the invention relates to suspension systems for intraocular lenses and more
  • the first need is to reduce the incision size required to install a replacement lens within the eye.
  • the second need is to conserve the natural geometry of the remnant lens capsule for improved safety and surgical outcome. More recently, a need to re-engage natural kinetics of the ciliary muscles of the eye with suspensory ligaments of the capsule in order to restore accommodation has emerged. [0005] The arrival of new generations of accommodating intraocular lenses has placed a renewed priority upon suspension systems that customize or self-adapt to exacting geometric parameters of the lens capsule.
  • embodiments are directed to other improvements.
  • the present invention provides a suspension system (haptic) for intraocular lenses which comprises an expandable body portion, such body portion comprising one or a plurality of hollow cavities, each hollow cavity comprising at least one opening communicating between the interior of the cavities and the exterior of the expandable haptic to permit ambient fluid to flow into and out of the hollow cavity and wherein the walls of the hollow cavities exhibit structure or elasticity to cause the walls to return to their original shapes after being compressed by an external force.
  • haptic for intraocular lenses which comprises an expandable body portion, such body portion comprising one or a plurality of hollow cavities, each hollow cavity comprising at least one opening communicating between the interior of the cavities and the exterior of the expandable haptic to permit ambient fluid to flow into and out of the hollow cavity and wherein the walls of the hollow cavities exhibit structure or elasticity to cause the walls to return to their original shapes after being compressed by an external force.
  • the cavities are laser sculpted but they may be cut or molded by other cutting or molding methods.
  • Figure 1 is a cross-section of a hollow rectangular box-shaped haptic element having laser sculpted compartments.
  • Figure 2 is a cross-section of a cylindrical element having a co-axial laser sculpted tubule.
  • Figure 3 is an elevation view of a haptic element having a plurality of laser sculpted tubules parallel to the optical axis of a lens.
  • Figure 4 is transverse cross-sectional view of a haptic element having a plurality of laser sculpted tubules in radial configuration relative to a lens.
  • Figure 5 is an transverse cross-sectional view of a haptic element having a plurality of laser sculpted tubules in tangential configuration relative to a lens.
  • Figure 6 is a cross section of hinged walls compressing laser sculpted tubules.
  • Figure 7 is a cross section of the hinged walls shown in Fig. 6 having been moved by decompression of the laser sculpted tubules.
  • the invention comprises laser sculpted compartments carved within haptics or
  • fluid is displaced out of the laser sculpted compartments by force generated by ciliary muscle action. Fluid re-enters the laser sculpted compartments by partial vacuums that are created by elastic properties of the walls of the laser sculpted compartments that allow them to return to their original resting state, once the force exerted by the ciliary muscles is relaxed.
  • laser sculpted compartments refers to the described
  • compartments in the haptic elements which have very small diameters or other dimensions. While these are preferably cut in such materials by lasers due to the fine dimensions involved, they may instead be formed in the elastic materials by other types of cutting or molding methods.
  • Figures 1 and 2 illustrate simple laser sculpted compartments carved within haptics or suspension systems of intraocular lenses.
  • Fig. 1 is a cross-section of a hollow, rectangular box-shaped haptic element 10. A plurality of laser-sculpted
  • compartments 12 are formed in the side walls 14 of the box-shaped element 10. Each compartment 12 has an orifice 16 that opens to the exterior of element 10 and an orifice 18 that opens to the hollow interior 20 of the element 10.
  • Fig. 2 illustrates in longitudinal cross-section an open-ended tubule having a laser-sculpted hollow cylindrical interior 24 formed within the cylindrical body 26 of the tubule and having orifices 28 open to the exterior of the tubule.
  • Figures 3, 4 and 5 illustrate patterns of laser sculpted tubules sculpted in various orientations within the haptic 30, 40, 50 of an intraocular lens. Each of these general patterns or combinations thereof, may be uniquely formatted for customized installation and fitting of an intraocular lens within the lens capsule of a human eye.
  • the laser sculpted tubules 32 are oriented parallel to each other and to the optical axis of a lens 34.
  • the laser sculpted tubules 42 are oriented in radial configuration relative to lens 44.
  • the laser sculpted tubules 52 are oriented in tangential configuration relative to lens 54.
  • cavities 32 in haptic 30 may be randomly oriented like a sponge
  • the laser sculpted hollow cavity or cavities have at least one opening whereby the cavity communicates with fluid in the external environment, such as ambient intraocular fluid, to allow fluid to flow into and out of the cavity.
  • fluid in the external environment such as ambient intraocular fluid
  • the haptic element compresses.
  • the walls lining the cavities exhibit sufficient structural form, memory and elasticity that they return toward their habitual shapes to draw fluid back into the cavities after the external force is reduced to allow the haptic element to decompress.
  • intraocular lenses require that the compartments return relatively slowly back to their habitual shapes, such as that described in my United States Patent no. 8,579,971 wherein the flow of ambient intraocular liquid back into a sealed compartment having semi-permeable walls is used to control compression forces acting upon an accommodating intraocular lens.
  • This same principle applies to the laser sculpted tubules of illustrated by Figures 4 and 5, but with more control and reliability than is attainable with the use of semi-permeable membranes in contact with liquids that establish osmotic gradients.
  • Another application of laser sculpted compartments within haptics of intraocular lenses is to allow for radial expansion as shown by the configuration of laser sculpted compartments 32 shown in Figure 3. Radial expansion is also useful in establishing the correct position and orientation of all intraocular lenses. Laser sculpted compartments with relatively large openings allow for rapid unfolding of the components of the haptic thereby facilitating rapid lens alignment required during the surgical installation process.
  • intraocular lenses pertains to the positioning of suspension elements that serve to hold the position of an intraocular lens within the empty lens compartment of the human eye.
  • Figures 6 and 7 illustrate a hinge 60 formed in a haptic region using laser sculpted tubules 62 formed in material 68 and compartment 63.
  • the arms 64, 66 are forced together, fluid is expelled from the tubules 62 and compartment 63.
  • pressure is released from the arms 64, 66, fluid is drawn back into the tubules 62 and compartment 63 to fill same causing material 68 to expand and open arms 64, 66.
  • This mechanism is particularly useful in guiding the re-configuration of an intraocular lens that is folded or compressed to fit through a small incision within the tunics of the eye prior to being placed within a vacant lens capsule.
  • the elastic features of the walls of compartments 12, 24, 32, 42, 52, 62 are provided by the material of the body portion of the haptic.
  • Materials used for such a body portion include but are not limited to the following classifications: silicones, silicone hydro-gels, hydrophobic and hydrophilic acrylics, polyethylene,
  • polypropylene, polyurethane and co-block polymers of these are polypropylene, polyurethane and co-block polymers of these.
  • Laser systems used to cut the foregoing materials generally comprise a source of ionizing, coherent radiant energy of short pulse duration so as to minimize the liberation of heat and material damage.
  • the diameter of cutting laser beams may be adjusted to as small as 8 microns. Therefore, the surface area of laser sculpted compartments ranges from that of a cylinder having the diameter of the laser beam to the overall area of the haptic of an intraocular lens.
  • the depth of the laser sculpted compartments may range from 0.2 mm to 12.0 mm.

Abstract

A suspension system (haptic) for intraocular lenses comprises an expandable body portion, such body portion comprising one or a plurality of hollow cavities, each hollow cavity comprising at least one opening communicating between the interior of the cavities and the exterior of the expandable haptic to permit ambient fluid to flow into and out of the hollow cavity and wherein the walls of the hollow cavities exhibit structure or elasticity to cause the walls to return toward their original shapes after being compressed by an external force.

Description

Expandable Suspension Systems for
Intraocular Lenses
Reference to Related Application
[0001] The present application claims the benefits, under 35 U.S.C.§ 1 19(e), of U.S.
Provisional Application Serial No. 61/761,569 filed February 6, 2013 entitled " Laser Sculpted Compartments within Suspension Systems for Intraocular Lenses" which is incorporated herein by this reference. [0002] The present invention relates to the applicant's inflatable lens/lens retainer as
disclosed in United States patent application no. 12/671 ,573 entitled INFLATABLE INTRAOCULAR LENS/LENS RETAINER filed Aug 12, 2008, now United States Patent no. 8,579,971, and which is incorporated herein by reference in its entirety.
Technical Field
[0003] The invention relates to suspension systems for intraocular lenses and more
particularly structures for intraocular expansion of such systems.
Background
[0004] For several decades, designers of intraocular lenses have envisioned
expandable/inflatable suspension systems or haptics that hold intraocular lenses upon the visual axis of a human eye after cataract surgery or lens extraction. Factors that have motivated these innovations relate to two general needs. The first need is to reduce the incision size required to install a replacement lens within the eye. The second need is to conserve the natural geometry of the remnant lens capsule for improved safety and surgical outcome. More recently, a need to re-engage natural kinetics of the ciliary muscles of the eye with suspensory ligaments of the capsule in order to restore accommodation has emerged. [0005] The arrival of new generations of accommodating intraocular lenses has placed a renewed priority upon suspension systems that customize or self-adapt to exacting geometric parameters of the lens capsule. Consequently, manufacturing processes that reduce logistical difficulties normally encountered with the assembly of expandable components within intraocular lens suspension systems are of commercial interest. [0006] In the past, the assembly of tiny, multi-component devices that allowed for expansion of intraocular lens suspension systems has been impractical; especially within a quality controlled production environment. Also, biocompatibility issues inherent with porous materials and adhesives required to secure these porous materials to the structure of intraocular lens suspension systems has been problematic. There is need for improvement in the manufacturing process for intraocular lens suspension systems.
[0007] The foregoing examples of the related art and limitations related thereto are intended to be illustrative and not exclusive. Other limitations of the related art will become apparent to those of skill in the art upon a reading of the specification and a study of the drawings.
Summary
[0008] The following embodiments and aspects thereof are described and illustrated in
conjunction with systems, tools and methods which are meant to be exemplary and illustrative, not limiting in scope. In various embodiments, one or more of the above-described problems have been reduced or eliminated, while other
embodiments are directed to other improvements.
[0009] The present invention provides a suspension system (haptic) for intraocular lenses which comprises an expandable body portion, such body portion comprising one or a plurality of hollow cavities, each hollow cavity comprising at least one opening communicating between the interior of the cavities and the exterior of the expandable haptic to permit ambient fluid to flow into and out of the hollow cavity and wherein the walls of the hollow cavities exhibit structure or elasticity to cause the walls to return to their original shapes after being compressed by an external force.
[0010] Preferably the cavities are laser sculpted but they may be cut or molded by other cutting or molding methods.
[0011] In addition to the exemplary aspects and embodiments described above, further
aspects and embodiments will become apparent by reference to the drawings and by study of the following detailed descriptions. Brief Description of Drawings
[0012] Exemplary embodiments are illustrated in referenced figures of the drawings. It is intended that the embodiments and figures disclosed herein are to be considered illustrative rather than restrictive.
[0013] Figure 1 is a cross-section of a hollow rectangular box-shaped haptic element having laser sculpted compartments.
[0014] Figure 2 is a cross-section of a cylindrical element having a co-axial laser sculpted tubule.
[0015] Figure 3 is an elevation view of a haptic element having a plurality of laser sculpted tubules parallel to the optical axis of a lens.
[0016] Figure 4 is transverse cross-sectional view of a haptic element having a plurality of laser sculpted tubules in radial configuration relative to a lens.
[0017] Figure 5 is an transverse cross-sectional view of a haptic element having a plurality of laser sculpted tubules in tangential configuration relative to a lens.
[0018] Figure 6 is a cross section of hinged walls compressing laser sculpted tubules.
[0019] Figure 7 is a cross section of the hinged walls shown in Fig. 6 having been moved by decompression of the laser sculpted tubules.
Description
[0020] Throughout the following description specific details are set forth in order to provide a more thorough understanding to persons skilled in the art. However, well known elements may not have been shown or described in detail to avoid unnecessarily obscuring the disclosure. Accordingly, the description and drawings are to be regarded in an illustrative, rather than a restrictive, sense.
[0021] The invention comprises laser sculpted compartments carved within haptics or
suspension systems of intraocular lenses. Within the lens capsule of the eye, fluid is displaced out of the laser sculpted compartments by force generated by ciliary muscle action. Fluid re-enters the laser sculpted compartments by partial vacuums that are created by elastic properties of the walls of the laser sculpted compartments that allow them to return to their original resting state, once the force exerted by the ciliary muscles is relaxed.
[0022] The term "laser sculpted compartments" used herein refers to the described
compartments in the haptic elements which have very small diameters or other dimensions. While these are preferably cut in such materials by lasers due to the fine dimensions involved, they may instead be formed in the elastic materials by other types of cutting or molding methods.
[0023] The rate of flow of liquid into and out of the laser sculpted compartments is
dependent upon a number of factors, which include but are not limited to the following; material elasticity, wall thickness, viscosity of the fluid moving into and out of the laser sculpted compartments, surface tension induced by the materials used to fabricate the walls of the laser sculpted compartments, the surface area of the orifice or orifices that communicate between the interior of the laser sculpted compartments and the surrounding fluid medium, the shape of the orifice or orifices of the laser sculpted compartments, strategic geometric patterns created by the location of multiple laser sculpted compartments, or any combination or permutation of these factors.
[0024] Figures 1 and 2 illustrate simple laser sculpted compartments carved within haptics or suspension systems of intraocular lenses. Fig. 1 is a cross-section of a hollow, rectangular box-shaped haptic element 10. A plurality of laser-sculpted
compartments 12 are formed in the side walls 14 of the box-shaped element 10. Each compartment 12 has an orifice 16 that opens to the exterior of element 10 and an orifice 18 that opens to the hollow interior 20 of the element 10. Fig. 2 illustrates in longitudinal cross-section an open-ended tubule having a laser-sculpted hollow cylindrical interior 24 formed within the cylindrical body 26 of the tubule and having orifices 28 open to the exterior of the tubule.
[0025] Figures 3, 4 and 5 illustrate patterns of laser sculpted tubules sculpted in various orientations within the haptic 30, 40, 50 of an intraocular lens. Each of these general patterns or combinations thereof, may be uniquely formatted for customized installation and fitting of an intraocular lens within the lens capsule of a human eye. In Fig. 3 the laser sculpted tubules 32 are oriented parallel to each other and to the optical axis of a lens 34. In Fig. 4 the laser sculpted tubules 42 are oriented in radial configuration relative to lens 44. In Fig. 5 the laser sculpted tubules 52 are oriented in tangential configuration relative to lens 54.
[0026] Alternatively cavities 32 in haptic 30 may be randomly oriented like a sponge,
provided a sufficient number of such cavities have openings to the exterior of the haptic.
[0027] In each of the foregoing for suspension systems for intraocular lenses (haptic
elements), the laser sculpted hollow cavity or cavities have at least one opening whereby the cavity communicates with fluid in the external environment, such as ambient intraocular fluid, to allow fluid to flow into and out of the cavity. When compressed the fluid flows out of the cavities and the haptic element compresses. The walls lining the cavities exhibit sufficient structural form, memory and elasticity that they return toward their habitual shapes to draw fluid back into the cavities after the external force is reduced to allow the haptic element to decompress. [0028] Certain applications for laser sculpted compartments within haptic regions of
intraocular lenses require that the compartments return relatively slowly back to their habitual shapes, such as that described in my United States Patent no. 8,579,971 wherein the flow of ambient intraocular liquid back into a sealed compartment having semi-permeable walls is used to control compression forces acting upon an accommodating intraocular lens. This same principle applies to the laser sculpted tubules of illustrated by Figures 4 and 5, but with more control and reliability than is attainable with the use of semi-permeable membranes in contact with liquids that establish osmotic gradients.
[0029] Another application of laser sculpted compartments within haptics of intraocular lenses is to allow for radial expansion as shown by the configuration of laser sculpted compartments 32 shown in Figure 3. Radial expansion is also useful in establishing the correct position and orientation of all intraocular lenses. Laser sculpted compartments with relatively large openings allow for rapid unfolding of the components of the haptic thereby facilitating rapid lens alignment required during the surgical installation process.
[0030] Another application of laser sculpted compartments within haptic regions of
intraocular lenses pertains to the positioning of suspension elements that serve to hold the position of an intraocular lens within the empty lens compartment of the human eye. Figures 6 and 7 illustrate a hinge 60 formed in a haptic region using laser sculpted tubules 62 formed in material 68 and compartment 63. When the arms 64, 66 are forced together, fluid is expelled from the tubules 62 and compartment 63. When pressure is released from the arms 64, 66, fluid is drawn back into the tubules 62 and compartment 63 to fill same causing material 68 to expand and open arms 64, 66. This mechanism is particularly useful in guiding the re-configuration of an intraocular lens that is folded or compressed to fit through a small incision within the tunics of the eye prior to being placed within a vacant lens capsule.
[0031] Preferably the elastic features of the walls of compartments 12, 24, 32, 42, 52, 62 are provided by the material of the body portion of the haptic. Materials used for such a body portion include but are not limited to the following classifications: silicones, silicone hydro-gels, hydrophobic and hydrophilic acrylics, polyethylene,
polypropylene, polyurethane and co-block polymers of these.
[0032] Laser systems used to cut the foregoing materials generally comprise a source of ionizing, coherent radiant energy of short pulse duration so as to minimize the liberation of heat and material damage. The diameter of cutting laser beams may be adjusted to as small as 8 microns. Therefore, the surface area of laser sculpted compartments ranges from that of a cylinder having the diameter of the laser beam to the overall area of the haptic of an intraocular lens. The depth of the laser sculpted compartments may range from 0.2 mm to 12.0 mm.
[0033] While a number of exemplary aspects of the embodiments have been discussed
above, those of skill in the art will recognize certain modifications, permutations, additions and sub-combinations thereof. It is therefore intended that the invention be interpreted to include all such modifications, permutations, additions and subcombinations as are within their true spirit and scope.

Claims

WHAT IS CLAIMED IS:
An expandable haptic for intraocular lenses comprising an expandable body portion, such body portion comprising one or a plurality of hollow cavities, each said hollow cavity comprising at least one opening communicating between the interior of said cavities and the exterior of said expandable haptic to permit ambient fluid to flow into and out of said hollow cavity and wherein the walls of said hollow cavities exhibit structure or elasticity to cause said walls to return to their original shapes after being compressed by an external force.
The expandable haptic of claim 1 wherein said ambient fluid is displaced from said cavities by force generated by ciliary muscle action, and said ambient fluid re-enters said cavities due to a reduction of pressure therein caused by elastic properties of the walls of said cavities causing said walls return to a resting state once the force generated by said ciliary muscle action is relaxed.
The expandable haptic of claim 1 wherein said walls of said cavities comprise sufficient structural form, memory or elasticity that they return toward to their original uncompressed shapes to draw fluid back into said cavities after said external force is reduced to thereby allow said expandable body portion to decompress.
The expandable haptic of claim 1 wherein said body portion comprises elastic material and said hollow cavities comprise laser-sculpted compartments formed in said elastic material.
The expandable haptic of claim 1 wherein said body portion comprises elastic material and said hollow cavities comprise compartments formed in said elastic material by cutting or molding methods.
The expandable haptic of claim 1 wherein the rate of flow of ambient fluid liquid into and out of said cavities is determined by a factor selected from the group consisting of the elasticity of said walls, thickness of said walls, viscosity of said ambient fluid, surface tension induced by the materials used to fabricate said walls, the cross- sectional area of said opening or openings that communicate between the interior of said cavities and the exterior of said expandable haptic, the shape of said opening or openings, the number, volume and geometric patterns created by said cavities, and any combination of these factors.
The expandable haptic of claim 1 wherein the geometric pattern created by said cavities is selected from the group consisting of parallel to each other and to the optical axis of a lens, radially extending relative to a circular lens and parallel and tangential relative to a circular lens.
The expandable haptic of claim 1 wherein said body comprises a hollow box shaped element and said cavities are formed in the walls of said box-shaped element.
The expandable haptic of claim 1 wherein said body comprises an open-ended cylindrical body and said cavity forms the interior of said cylindrical body.
The expandable haptic of claim 1 wherein said body comprises a plurality of parallel tubular cavities oriented parallel to the optical axis of a lens.
The expandable haptic of claim 1 wherein said body comprises a plurality of tubular cavities oriented in radial configuration relative to a circular lens.
The expandable haptic of claim 1 wherein said body comprises a plurality of parallel tubular cavities oriented in tangential configuration relative to a circular lens.
The expandable haptic of claim 1 wherein said body comprises a plurality of cavities randomly oriented wherein a sufficient number of such cavities have openings to the exterior of the haptic.
The expandable haptic of claim 1 comprising a hinge comprising two arms pivotally connected at a hinge element and wherein said body is situated between and connected to said arms and comprises a plurality of said cavities whereby when said arms are forced together, said fluid is expelled from said cavities and when pressure is released from said arms said fluid is drawn back into said cavities to expand said body portion and open said hinge. A suspension system for intraocular lenses comprising the expandable haptic claim 1.
PCT/CA2014/050074 2013-02-06 2014-02-06 Expandable suspension systems for intraocular lenses WO2014121391A1 (en)

Applications Claiming Priority (2)

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US201361761569P 2013-02-06 2013-02-06
US61/761,569 2013-02-06

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017181295A1 (en) * 2016-04-22 2017-10-26 Ventura Holdings Ltd. Collapsible cavities within suspension systems for intra-ocular lenses
CN109152658A (en) * 2016-05-25 2019-01-04 文图拉控股有限公司 For collapsing cavity in the suspension of intraocular lens
US10939994B2 (en) 2016-04-22 2021-03-09 Ventura Holdings Ltd. Collapsible cavities within suspension systems for intra-ocular lenses

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Publication number Priority date Publication date Assignee Title
WO2017181295A1 (en) * 2016-04-22 2017-10-26 Ventura Holdings Ltd. Collapsible cavities within suspension systems for intra-ocular lenses
EP3445299A4 (en) * 2016-04-22 2020-01-01 Ventura Holdings Ltd. Collapsible cavities within suspension systems for intra-ocular lenses
US10939994B2 (en) 2016-04-22 2021-03-09 Ventura Holdings Ltd. Collapsible cavities within suspension systems for intra-ocular lenses
AU2017254764B2 (en) * 2016-04-22 2022-04-07 Ocumetics Technology Corp. Collapsible cavities within suspension systems for intra-ocular lenses
AU2017254764B9 (en) * 2016-04-22 2022-04-14 Ocumetics Technology Corp. Collapsible cavities within suspension systems for intra-ocular lenses
CN109152658A (en) * 2016-05-25 2019-01-04 文图拉控股有限公司 For collapsing cavity in the suspension of intraocular lens
CN109152658B (en) * 2016-05-25 2022-04-19 眼科技术公司 Collapsible chamber within a suspension system for an intraocular lens

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