WO2009134991A3 - Tissue engineered blood vessel - Google Patents

Tissue engineered blood vessel Download PDF

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Publication number
WO2009134991A3
WO2009134991A3 PCT/US2009/042293 US2009042293W WO2009134991A3 WO 2009134991 A3 WO2009134991 A3 WO 2009134991A3 US 2009042293 W US2009042293 W US 2009042293W WO 2009134991 A3 WO2009134991 A3 WO 2009134991A3
Authority
WO
WIPO (PCT)
Prior art keywords
tissue engineered
blood vessel
engineered blood
blood vessels
tissue
Prior art date
Application number
PCT/US2009/042293
Other languages
French (fr)
Other versions
WO2009134991A2 (en
Inventor
Kevin Cooper
Iksoo Chun
David C. Colter
Sridevi Dhanaraj
Anna Gosiewska
Agnieszka Seyda
Christian Kazanecki
Chunlin Yang
Original Assignee
Ethicon, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ethicon, Inc. filed Critical Ethicon, Inc.
Priority to CA2723141A priority Critical patent/CA2723141A1/en
Priority to JP2011507640A priority patent/JP2011519616A/en
Priority to CN200980125918.6A priority patent/CN102076366B/en
Priority to EP09739793.9A priority patent/EP2268326B1/en
Publication of WO2009134991A2 publication Critical patent/WO2009134991A2/en
Publication of WO2009134991A3 publication Critical patent/WO2009134991A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/069—Vascular Endothelial cells
    • C12N5/0691—Vascular smooth muscle cells; 3D culture thereof, e.g. models of blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/507—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials for artificial blood vessels
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/08—Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/14—Scaffolds; Matrices

Abstract

Compositions and methods of using tissue engineered blood vessels to repair and regenerate blood vessels of patients with vascular disease are disclosed.
PCT/US2009/042293 2008-04-30 2009-04-30 Tissue engineered blood vessel WO2009134991A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA2723141A CA2723141A1 (en) 2008-04-30 2009-04-30 Tissue engineered blood vessel
JP2011507640A JP2011519616A (en) 2008-04-30 2009-04-30 Blood vessels by tissue engineering
CN200980125918.6A CN102076366B (en) 2008-04-30 2009-04-30 Tissue engineered blood vessel
EP09739793.9A EP2268326B1 (en) 2008-04-30 2009-04-30 Tissue engineered blood vessel

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4906708P 2008-04-30 2008-04-30
US61/049,067 2008-04-30

Publications (2)

Publication Number Publication Date
WO2009134991A2 WO2009134991A2 (en) 2009-11-05
WO2009134991A3 true WO2009134991A3 (en) 2010-07-29

Family

ID=41110839

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2009/042293 WO2009134991A2 (en) 2008-04-30 2009-04-30 Tissue engineered blood vessel

Country Status (6)

Country Link
US (5) US20090275129A1 (en)
EP (1) EP2268326B1 (en)
JP (1) JP2011519616A (en)
CN (1) CN102076366B (en)
CA (1) CA2723141A1 (en)
WO (1) WO2009134991A2 (en)

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DK2854735T3 (en) 2012-05-24 2019-05-13 Takeda As DEVICE AND PROCEDURE FOR MANUFACTURING AN INCORPORATED CARBON CARRIER
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CN103230309B (en) * 2013-05-07 2015-07-29 上海交通大学医学院附属上海儿童医学中心 A kind of engineering blood vessel and its production and use
US20160114081A1 (en) * 2013-05-31 2016-04-28 Francesco Serino Methods and compositions for blood vessel tissue repair and engineering
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CN107456296B (en) * 2016-09-14 2020-07-14 四川蓝光英诺生物科技股份有限公司 Lumen tissue construct, method and device for producing lumen tissue construct
CN107411845A (en) * 2016-09-14 2017-12-01 四川蓝光英诺生物科技股份有限公司 Lumen organization's construct, lumen organization's structure preparation and its device
CN106924817B (en) * 2017-03-02 2019-12-17 浙江大学 Ultrathin carrier cell sheet and preparation method thereof
IT201700093925A1 (en) * 2017-08-16 2019-02-16 1Lab Sa A reliable and reproducible process of industrialization of the elimination of air bubbles for the production of an engineered vascular tissue.
JP7412174B2 (en) * 2017-10-31 2024-01-12 株式会社Adeka Sheet-shaped decellularized material and artificial blood vessels using the same material
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DE112022001103T5 (en) * 2021-02-17 2024-02-22 Fukuoka University Cell sheet supports, cell sheet laminates and process for their production
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Also Published As

Publication number Publication date
CN102076366A (en) 2011-05-25
US9290742B2 (en) 2016-03-22
CA2723141A1 (en) 2009-11-05
EP2268326B1 (en) 2016-11-23
US20130203168A1 (en) 2013-08-08
US20090275129A1 (en) 2009-11-05
US20130196431A1 (en) 2013-08-01
US20130196440A1 (en) 2013-08-01
JP2011519616A (en) 2011-07-14
EP2268326A2 (en) 2011-01-05
CN102076366B (en) 2014-06-11
WO2009134991A2 (en) 2009-11-05
US20130196439A1 (en) 2013-08-01

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