WO2009020797A3 - Polymers for implantable devices exhibiting shape-memory effects - Google Patents

Polymers for implantable devices exhibiting shape-memory effects Download PDF

Info

Publication number
WO2009020797A3
WO2009020797A3 PCT/US2008/071453 US2008071453W WO2009020797A3 WO 2009020797 A3 WO2009020797 A3 WO 2009020797A3 US 2008071453 W US2008071453 W US 2008071453W WO 2009020797 A3 WO2009020797 A3 WO 2009020797A3
Authority
WO
WIPO (PCT)
Prior art keywords
implantable devices
compositions
polymers
polymeric compositions
memory effects
Prior art date
Application number
PCT/US2008/071453
Other languages
French (fr)
Other versions
WO2009020797A2 (en
Inventor
John Stankus
Mikael O. Trollsas
Michael H. Ngo
Original Assignee
Abbott Cardiovascular Systems Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Cardiovascular Systems Inc. filed Critical Abbott Cardiovascular Systems Inc.
Publication of WO2009020797A2 publication Critical patent/WO2009020797A2/en
Publication of WO2009020797A3 publication Critical patent/WO2009020797A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/18Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28Materials for coating prostheses
    • A61L27/34Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/16Materials with shape-memory or superelastic properties
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2230/00Compositions for preparing biodegradable polymers
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2280/00Compositions for creating shape memory
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L75/00Compositions of polyureas or polyurethanes; Compositions of derivatives of such polymers
    • C08L75/04Polyurethanes

Abstract

The present invention is directed to polymeric compositions comprising a biodegradable copolymer that possesses shape-memory properties and implantable devices (e.g., drug-delivery stents) formed of materials (e.g., a coating) containing such compositions. The polymeric compositions can also contain at least one non-fouling moiety, at least additional biocompatible polymer, at least one biobeneficial material, at least one bioactive agent, or a combination thereof. The polymeric compositions are formulated to possess good mechanical, physical and biological properties. Moreover, implantable devices formed of materials comprising such compositions can be delivered to the treatment site in a conveniently compressed size and then can expand to dimensions appropriate for their medical functions.
PCT/US2008/071453 2007-08-03 2008-07-29 Polymers for implantable devices exhibiting shape-memory effects WO2009020797A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/888,940 2007-08-03
US11/888,940 US20090035350A1 (en) 2007-08-03 2007-08-03 Polymers for implantable devices exhibiting shape-memory effects

Publications (2)

Publication Number Publication Date
WO2009020797A2 WO2009020797A2 (en) 2009-02-12
WO2009020797A3 true WO2009020797A3 (en) 2009-11-05

Family

ID=40266039

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/071453 WO2009020797A2 (en) 2007-08-03 2008-07-29 Polymers for implantable devices exhibiting shape-memory effects

Country Status (2)

Country Link
US (2) US20090035350A1 (en)
WO (1) WO2009020797A2 (en)

Families Citing this family (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7758881B2 (en) * 2004-06-30 2010-07-20 Advanced Cardiovascular Systems, Inc. Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders with an implantable medical device
US8435550B2 (en) 2002-12-16 2013-05-07 Abbot Cardiovascular Systems Inc. Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders with an implantable medical device
US8703066B2 (en) * 2004-01-07 2014-04-22 Noxilizer, Inc. Sterilization system and method
US8017074B2 (en) 2004-01-07 2011-09-13 Noxilizer, Inc. Sterilization system and device
US8709469B2 (en) 2004-06-30 2014-04-29 Abbott Cardiovascular Systems Inc. Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders with an implantable medical device
US20100070020A1 (en) 2008-06-11 2010-03-18 Nanovasc, Inc. Implantable Medical Device
US20090035350A1 (en) 2007-08-03 2009-02-05 John Stankus Polymers for implantable devices exhibiting shape-memory effects
US9259515B2 (en) * 2008-04-10 2016-02-16 Abbott Cardiovascular Systems Inc. Implantable medical devices fabricated from polyurethanes with grafted radiopaque groups
WO2009132070A2 (en) 2008-04-22 2009-10-29 The Regents Of The University Of Colorado, A Body Corporate Thiol-vinyl and thiol-yne systems for shape memory polymers
US10898620B2 (en) 2008-06-20 2021-01-26 Razmodics Llc Composite stent having multi-axial flexibility and method of manufacture thereof
US8206636B2 (en) 2008-06-20 2012-06-26 Amaranth Medical Pte. Stent fabrication via tubular casting processes
US8206635B2 (en) 2008-06-20 2012-06-26 Amaranth Medical Pte. Stent fabrication via tubular casting processes
US8119742B2 (en) * 2008-09-28 2012-02-21 Knc Ner Acquisition Sub, Inc. Multi-armed catechol compound blends
WO2010042918A1 (en) 2008-10-11 2010-04-15 Rutgers, The State University Of New Jersey Biocompatible polymers for medical devices
WO2010096766A1 (en) 2009-02-23 2010-08-26 Noxilizer, Inc. Device and method for gas sterilization
JP5944314B2 (en) 2009-07-31 2016-07-05 ラトガース,ザ ステート ユニバーシティ オブ ニュー ジャージー Biocompatible polymers for medical devices
FI123146B (en) 2009-10-01 2012-11-30 Bayer Schering Pharma Oy An intrauterine system
AU2010303170B2 (en) 2009-10-11 2015-02-26 Rutgers, The State University Of New Jersey Biocompatible polymers for medical devices
CN102188746B (en) * 2010-03-11 2013-08-14 北京益而康生物工程开发中心 Artificial extracellular matrix and preparation method thereof
WO2011115582A1 (en) 2010-03-18 2011-09-22 Agency For Science, Technology And Research Biodegradable and biocompatible shape memory polymers
US20120059451A1 (en) * 2010-09-08 2012-03-08 Qiang Zhang Method of Manufacturing a Polymeric Stent Having Reduced Recoil
WO2013027556A1 (en) * 2011-08-22 2013-02-28 テルモ株式会社 Antithrombogenic material and medical device
US9416090B2 (en) 2012-02-03 2016-08-16 Rutgers, The State University Of New Jersey Polymeric biomaterials derived from phenolic monomers and their medical uses
US11472918B2 (en) 2012-02-03 2022-10-18 Rutgers, The State University Of New Jersey Polymeric biomaterials derived from phenolic monomers and their medical uses
WO2013176739A1 (en) * 2012-05-25 2013-11-28 Regents Of The University Of Minnesota Biomaterials with a sustainable surface
US9422393B2 (en) * 2012-11-13 2016-08-23 Syracuse University Water-triggered shape memory of PCL-PEG multiblock TPUs
CN114131923A (en) 2014-06-23 2022-03-04 卡本有限公司 Method for producing three-dimensional objects of polyurethane from materials with multiple hardening mechanisms
WO2016012984A1 (en) * 2014-07-25 2016-01-28 Legatoria Gps Srl Uninominale Vinyl adhesive composition and associated binding method
CA2961972C (en) * 2014-09-26 2022-11-22 Dsm Ip Assets B.V. Osteointegrative composition for medical implants
US9708441B2 (en) * 2014-10-06 2017-07-18 Plactis Industry Development Center Low temperature shape memory thermosetting epoxy, film material and producing method thereof
CN104387552B (en) * 2014-11-24 2017-06-13 鹤山雅图仕印刷有限公司 Degradable UV-cured resin and preparation method thereof and the application in paper coating material
AU2015370426B2 (en) 2014-12-23 2019-09-12 Rutgers, The State University Of New Jersey Biocompatible iodinated diphenol monomers and polymers
US10774030B2 (en) 2014-12-23 2020-09-15 Rutgers, The State University Of New Jersey Polymeric biomaterials derived from phenolic monomers and their medical uses
EP3061777B1 (en) 2015-02-24 2021-11-24 Albert-Ludwigs-Universität Freiburg Phase-segregated block copolymers with tunable properties
WO2016145050A1 (en) 2015-03-10 2016-09-15 Carbon3D, Inc. Microfluidic devices having flexible features and methods of making the same
US10538031B2 (en) 2015-12-22 2020-01-21 Carbon, Inc. Dual cure additive manufacturing of rigid intermediates that generate semi-rigid, flexible, or elastic final products
WO2017112483A2 (en) 2015-12-22 2017-06-29 Carbon, Inc. Accelerants for additive manufacturing with dual cure resins
EP3394673A1 (en) 2015-12-22 2018-10-31 Carbon, Inc. Fabrication of compound products from multiple intermediates by additive manufacturing with dual cure resins
WO2017112521A1 (en) 2015-12-22 2017-06-29 Carbon, Inc. Production of flexible products by additive manufacturing with dual cure resins
JP7189015B2 (en) 2015-12-22 2022-12-13 カーボン,インコーポレイテッド A Dual Precursor Resin System for Additive Manufacturing Using Dual Cured Resins
WO2017112751A1 (en) 2015-12-22 2017-06-29 Carbon, Inc. Blocked silicone dual cure resins for additive manufacturing
US11155670B2 (en) 2016-08-24 2021-10-26 Board Of Regents, The University Of Texas System Amorphous thermoset thiourethane polymers, method of synthesis thereof and use in bio-electronic devices
CA3046087A1 (en) 2016-12-09 2018-06-14 Zenflow, Inc. Systems, devices, and methods for the accurate deployment of an implant in the prostatic urethra
US10316213B1 (en) 2017-05-01 2019-06-11 Formlabs, Inc. Dual-cure resins and related methods
CN112386747B (en) * 2017-06-02 2022-04-12 天津工业大学 Ureteral stent tube with shape memory function and preparation method and application thereof
WO2018226991A1 (en) 2017-06-07 2018-12-13 Shifamed Holdings, Llc Intravascular fluid movement devices, systems, and methods of use
CN109306048A (en) * 2017-07-27 2019-02-05 天津科技大学 A kind of preparation method for the PEG-b-PHBV polymer micelle loading resveratrol
CN107715176A (en) * 2017-10-31 2018-02-23 无锡中科光远生物材料有限公司 A kind of preparation method of the nanofiber coating support of promotion osteanagenesis
WO2019094963A1 (en) 2017-11-13 2019-05-16 Shifamed Holdings, Llc Intravascular fluid movement devices, systems, and methods of use
EP3746149A4 (en) 2018-02-01 2021-10-27 Shifamed Holdings, LLC Intravascular blood pumps and methods of use and manufacture
CN109381750B (en) * 2018-05-09 2020-08-18 张锋 Anticoagulation conveniently-taken heart stent
CN109224139B (en) * 2018-05-09 2020-08-18 祖晓麟 Thermosensitive heart stent
EP3594257A1 (en) 2018-07-13 2020-01-15 Albert-Ludwigs-Universität Freiburg Use of phase segregated block copolymers with tiunable properties for the coating or surfces and coated substrates
CN108744010A (en) * 2018-07-09 2018-11-06 合肥洁诺医疗用品有限公司 A kind of preparation method of medical modified polypropene adhesive-bonded fabric dressing
CN112957516B (en) * 2018-08-20 2022-08-09 稳得希林(杭州)生物科技有限公司 Polysaccharide-based tissue adhesive medical adhesive and application thereof
US11439495B2 (en) * 2018-08-22 2022-09-13 Cook Medical Technologies Llc Self-healing graft material and method of use thereof
CN111234187B (en) * 2018-11-29 2022-09-20 中国石油化工股份有限公司 Shape memory polyether ester and preparation method and application thereof
CN110124112B (en) * 2019-04-02 2021-11-23 华南理工大学 Halloysite and arginine-based modified polyester urea-urethane composite material and preparation and application thereof
CN110218291A (en) * 2019-06-01 2019-09-10 湘潭大学 A kind of amphipathic nature block polymer and the preparation method and application thereof containing disulfide bond
CN110183613A (en) * 2019-06-03 2019-08-30 湘潭大学 A kind of preparation and application of amphipathic copolymer and its nano-micelle system
CN110205066B (en) * 2019-06-20 2021-07-02 佛山南宝高盛高新材料有限公司 Thermoplastic modified starch hot melt adhesive and preparation method thereof
US20210017329A1 (en) * 2019-07-19 2021-01-21 Evonik Operations Gmbh Multi-block shape memory bioresorbable polymers
WO2021016372A1 (en) 2019-07-22 2021-01-28 Shifamed Holdings, Llc Intravascular blood pumps with struts and methods of use and manufacture
CN110404070B (en) * 2019-08-21 2022-03-18 上海理工大学 PVP modified sodium alginate/polydopamine composite nano material and preparation and application thereof
CN110616507A (en) * 2019-08-29 2019-12-27 上海长海医院 Drug-loaded nanofiber membrane for preventing nasal cavity infection adhesion and preparation method thereof
WO2021062265A1 (en) 2019-09-25 2021-04-01 Shifamed Holdings, Llc Intravascular blood pump systems and methods of use and control thereof
AU2020387396A1 (en) 2019-11-19 2022-04-21 Zenflow, Inc. Systems, devices, and methods for the accurate deployment and imaging of an implant in the prostatic urethra
CN111701081B (en) * 2020-06-23 2021-11-16 首都医科大学 Drug coating liquid for drug-coated balloon and drug-coated balloon
CN114129780B (en) * 2020-09-03 2022-06-28 天津大学 Preparation and application of light-operated nitric oxide releasing composite hydrogel
CN112316202B (en) * 2020-11-13 2022-04-01 南通大学 Shape memory hemostatic material and preparation method and application thereof
CN113181437B (en) * 2021-03-16 2022-09-23 浙江大学 Customizable polymer intravascular stent and preparation method thereof
CN113527627A (en) * 2021-08-18 2021-10-22 中国科学院海洋研究所 Polylactic acid polycarbonate-based polyurethane with self-repairing function and preparation method and application thereof
CN115105632B (en) * 2022-07-15 2023-12-01 重庆大学 Application of polylactic acid and shape memory polyurethane material compound in preparation of bone repair material

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006115799A1 (en) * 2005-04-21 2006-11-02 University Of Connecticut Shape memory polymers based on semicrystalline thermoplastic polyurethanes bearing nanostructured hard segments

Family Cites Families (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4284506A (en) * 1979-12-26 1981-08-18 Nl Industries, Inc. Biomedical devices
JP2502132B2 (en) * 1988-09-30 1996-05-29 三菱重工業株式会社 Shape memory polyurethane elastomer molded body
ES2060075T3 (en) * 1990-02-23 1994-11-16 Minnesota Mining & Mfg SEMI-THERMOPLASTIC COMPOSITION FOR MOLDING THAT HAS MEMORY IN A "CUSTOMIZED" FORM, THERMALLY STABLE.
US6074747A (en) * 1995-06-06 2000-06-13 Avery Dennison Corporation Ink-imprintable release coatings, and pressure sensitive adhesive constructions
DE19520732A1 (en) * 1995-06-07 1996-12-12 Bayer Ag Thermoplastic polyurethane elastomers
FR2739625B1 (en) * 1995-10-09 1997-12-05 Atochem Elf Sa ASSOCIATIVE WATER-SOLUBLE COPOLYMERS TRIBLOCS
BR9611977A (en) * 1995-12-08 1999-02-17 Ici Plc Elastomer based on polyisocyanate and process for the preparation of elastomers
US6696499B1 (en) * 1996-07-11 2004-02-24 Life Medical Sciences, Inc. Methods and compositions for reducing or eliminating post-surgical adhesion formation
US6545384B1 (en) * 1997-02-07 2003-04-08 Sri International Electroactive polymer devices
US6221997B1 (en) * 1997-04-28 2001-04-24 Kimberly Ann Woodhouse Biodegradable polyurethanes
US6211249B1 (en) * 1997-07-11 2001-04-03 Life Medical Sciences, Inc. Polyester polyether block copolymers
US7985415B2 (en) * 1997-09-10 2011-07-26 Rutgers, The State University Of New Jersey Medical devices employing novel polymers
WO1999042147A1 (en) * 1998-02-23 1999-08-26 Massachusetts Institute Of Technology Biodegradable shape memory polymers
ES2265186T3 (en) * 1998-02-23 2007-02-01 Mnemoscience Gmbh POLYMERS WITH FORM MEMORY.
BR9910968B1 (en) * 1998-06-05 2009-05-05 biodegradable biomedical polyurethane, process for preparing a biomedical polyurethane, implants based on biomedical polyurethanes, and use of a polyurethane.
US6100310A (en) * 1998-09-25 2000-08-08 Bayer Antwerp N.V. Process for making microcellular polyurethane elastomers
WO2000021585A1 (en) * 1998-10-13 2000-04-20 Gambro Ab Biocompatible polymer film
CA2254002A1 (en) * 1998-11-12 2000-05-12 Takiron Co., Ltd. Shape-memory, biodegradable and absorbable material
AUPQ170799A0 (en) * 1999-07-20 1999-08-12 Cardiac Crc Nominees Pty Limited Shape memory polyurethane or polyurethane-urea polymers
WO2001014444A1 (en) * 1999-08-19 2001-03-01 Asahi Kasei Kabushiki Kaisha Polyether polyurethane
US6639041B2 (en) * 1999-12-03 2003-10-28 Dupont-Toray Co. Ltd. Spandex having low set at low temperatures
DE10020163B4 (en) * 2000-04-25 2007-05-31 Bayer Materialscience Ag Aliphatic thermoplastic polyurethanes and their use
CA2410637C (en) * 2000-05-31 2007-04-10 Mnemoscience Gmbh Shape memory polymers seeded with dissociated cells for tissue engineering
US6613314B1 (en) * 2000-07-27 2003-09-02 L'oreal Reshapable hair styling composition comprising polyurethane dispersions
EP1178063A1 (en) * 2000-08-01 2002-02-06 Huntsman International Llc Process for preparing a polyurethane material
US20020120333A1 (en) * 2001-01-31 2002-08-29 Keogh James R. Method for coating medical device surfaces
WO2003029318A1 (en) * 2001-09-26 2003-04-10 Basf Aktiengesellschaft Cross-linkable polyurethane block copolymers and their use in dispersion binding agent systems
US6809152B2 (en) * 2001-10-22 2004-10-26 Acushnet Company Golf ball cover with segmented polyurethane
DE50309990D1 (en) * 2002-02-22 2008-07-31 Jowat Ag Polyurethane compositions with low content of diisocyanate monomer (s)
DE10217350C1 (en) * 2002-04-18 2003-12-18 Mnemoscience Gmbh polyesterurethanes
WO2003088818A2 (en) * 2002-04-18 2003-10-30 Mnemoscience Gmbh Biodegradable shape memory polymeric sutures
US20040030062A1 (en) * 2002-05-02 2004-02-12 Mather Patrick T. Castable shape memory polymers
US6852823B2 (en) * 2002-08-09 2005-02-08 E. I. Du Pont De Nemours And Company Polyurethane and polyurethane-urea elastomers from polytrimethylene ether glycol
US6946539B2 (en) * 2002-08-09 2005-09-20 E. I. Du Pont De Nemours And Company Polyurethane and polyurethane-urea comprised of poly(trimethylene-ethylene ether) glycol soft segment
US7091297B2 (en) * 2002-10-11 2006-08-15 The University Of Connecticut Shape memory polymers based on semicrystalline thermoplastic polyurethanes bearing nanostructured hard segments
US7985414B2 (en) * 2003-02-04 2011-07-26 Warsaw Orthopedic, Inc. Polyurethanes for osteoimplants
JP3924258B2 (en) * 2003-04-01 2007-06-06 三菱重工業株式会社 Manufacturing method of fiber reinforced plastic
DE10316573A1 (en) * 2003-04-10 2004-11-04 Mnemoscience Gmbh Blends with shape-memory properties
US7641643B2 (en) * 2003-04-15 2010-01-05 Abbott Cardiovascular Systems Inc. Methods and compositions to treat myocardial conditions
US7563454B1 (en) * 2003-05-01 2009-07-21 Advanced Cardiovascular Systems, Inc. Coatings for implantable medical devices
US7662864B2 (en) * 2003-06-04 2010-02-16 Rutgers, The State University Of New Jersey Solution polymerization processes to prepare a polymer that degrades to release a physiologically active agent
WO2004110315A1 (en) 2003-06-16 2004-12-23 Nanyang Technological University Polymeric stent and method of manufacture
DE10340392A1 (en) * 2003-09-02 2005-04-07 Mnemoscience Gmbh Amorphous polyester urethane networks with shape-memory properties
US20050107563A1 (en) * 2003-11-19 2005-05-19 The Hong Kong Polytechnic University Methods for manufacturing polyurethanes
US20050197480A1 (en) * 2004-03-05 2005-09-08 Temple Rodger G. Barrier coating comprising a polyurethane dispersion and elastomeric material
US9034378B2 (en) * 2004-03-24 2015-05-19 Polynovo Biomaterials Pty Ltd Biodegradable polyurethane and polyurethane ureas
EP1771490B1 (en) * 2004-07-26 2019-01-02 Synthes GmbH Biocompatible, biodegradable polyurethane materials with controlled hydrophobic to hydrophilic ratio
US20060036045A1 (en) * 2004-08-16 2006-02-16 The Regents Of The University Of California Shape memory polymers
WO2006034128A2 (en) * 2004-09-17 2006-03-30 Angiotech Biomaterials Corporation Multifunctional compounds for forming crosslinked biomaterials and methods of preparation and use
US20060178497A1 (en) * 2005-02-04 2006-08-10 Clemson University And Thordon Bearings, Inc. Implantable biomedical devices including biocompatible polyurethanes
US7964695B2 (en) * 2005-03-28 2011-06-21 Albemarle Corporation Chain extenders
EP1790694A1 (en) * 2005-11-28 2007-05-30 Mnemoscience GmbH Blends of shape memory polymers with thermoplastic polymers
DE102006012169B4 (en) * 2006-03-14 2007-12-13 Gkss-Forschungszentrum Geesthacht Gmbh Shape memory polymer with polyester and polyether segments, process for its preparation and shape programming and use
US8486135B2 (en) * 2006-06-01 2013-07-16 Abbott Cardiovascular Systems Inc. Implantable medical devices fabricated from branched polymers
WO2008008266A2 (en) * 2006-07-07 2008-01-17 University Of Pittsburgh- Of The Commonwealth System Of Higher Education Biohybrid elastomeric scaffolds and methods of use thereof
US20090181063A1 (en) * 2006-07-13 2009-07-16 Michael Huy Ngo Implantable medical device comprising a pro-healing poly(ester-amide)
US20090004243A1 (en) * 2007-06-29 2009-01-01 Pacetti Stephen D Biodegradable triblock copolymers for implantable devices
US20090035350A1 (en) 2007-08-03 2009-02-05 John Stankus Polymers for implantable devices exhibiting shape-memory effects
US20090041845A1 (en) * 2007-08-08 2009-02-12 Lothar Walter Kleiner Implantable medical devices having thin absorbable coatings
US20090110713A1 (en) * 2007-10-31 2009-04-30 Florencia Lim Biodegradable polymeric materials providing controlled release of hydrophobic drugs from implantable devices

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006115799A1 (en) * 2005-04-21 2006-11-02 University Of Connecticut Shape memory polymers based on semicrystalline thermoplastic polyurethanes bearing nanostructured hard segments

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BYUNG K K ET AL: "Polyurethanes having shape memory effects", POLYMER, ELSEVIER SCIENCE PUBLISHERS B.V, GB, vol. 37, no. 26, 1 January 1996 (1996-01-01), pages 5781 - 5793, XP004070893, ISSN: 0032-3861 *

Also Published As

Publication number Publication date
US20140010858A1 (en) 2014-01-09
WO2009020797A2 (en) 2009-02-12
US9066992B2 (en) 2015-06-30
US20090035350A1 (en) 2009-02-05

Similar Documents

Publication Publication Date Title
WO2009020797A3 (en) Polymers for implantable devices exhibiting shape-memory effects
EP2792696A3 (en) Biodegradable Polymeric Materials Providing Controlled Release of Hydrophobic Drugs from Implantable Devices
WO2009005909A3 (en) Biodegradable triblock copolymers for implantable devices
Liu et al. Injectable dopamine-modified poly (ethylene glycol) nanocomposite hydrogel with enhanced adhesive property and bioactivity
Lakes et al. Synthesis and characterization of an antibacterial hydrogel containing covalently bound vancomycin
WO2007092559A3 (en) A poly (diol-co-citrate) hydroxyapatite composite for tissue engineering and orthopaedic fixation devices
WO2007024481A3 (en) 4-aza-caprolactone-based polymeric compositions useful for the manufacture of biodegradable medical devices and as medical device coatings
WO2010005721A3 (en) Drug loaded polymeric nanoparticles and methods of making and using same
EP1837042A3 (en) Implantable device formed from polymer blends having modified molecular structures
WO2007041593A3 (en) Anti-scarring drug combinations and use thereof
WO2007111808A3 (en) Medical devices having biodegradable polymeric regions
WO2007139760A3 (en) Resorbable polymer compositions for use in medicine, dentistry, and surgery
WO2006023130A3 (en) Biodegradable controlled release bioactive agent delivery device
WO2010039641A3 (en) Long term drug delivery devices with polyurethane-based polymers and their manufacture
WO2005112587A3 (en) Wound healing polymer compositions and methods for use thereof
ATE532540T1 (en) MODULAR BIORESORBABLE OR BIOMEDICAL BIOLOGICALLY ACTIVE SUPRAMOLECULAR SUBSTANCES
WO2007100883A3 (en) Antimicrobial releasing polymers
WO2005051316A3 (en) Polymer compositions and methods for their use
WO2008011615A3 (en) Bioabsorbable polymeric composition for a medical device
WO2005120462A3 (en) Biodegradable and biocompatible crosslinked polymer hydrogel prepared from pva and/or peg macromer mixtures
WO2007038246A3 (en) Solid polymer delivery compositions and methods for use thereof
WO2006074391A3 (en) Biodegradable coating compositions comprising blends
WO2011079279A3 (en) Nanoconjugates and nanoconjugate formulations
Overstreet et al. In situ forming, resorbable graft copolymer hydrogels providing controlled drug release
WO2007092418A3 (en) Polymeric, degradable drug-eluting stents and coatings

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08827110

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 08827110

Country of ref document: EP

Kind code of ref document: A2