WO2008120156A3 - System and method for pill communication and control - Google Patents

System and method for pill communication and control Download PDF

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Publication number
WO2008120156A3
WO2008120156A3 PCT/IB2008/051170 IB2008051170W WO2008120156A3 WO 2008120156 A3 WO2008120156 A3 WO 2008120156A3 IB 2008051170 W IB2008051170 W IB 2008051170W WO 2008120156 A3 WO2008120156 A3 WO 2008120156A3
Authority
WO
WIPO (PCT)
Prior art keywords
pill
shell
medicine
communicator
information
Prior art date
Application number
PCT/IB2008/051170
Other languages
French (fr)
Other versions
WO2008120156A2 (en
Inventor
Karen I Trovato
Pim T Tuyls
Helen F Routh
Jeff Shimizu
Johan F Dijksman
Anke Pierik
Judith M Rensen
Hans Zou
Original Assignee
Koninkl Philips Electronics Nv
Karen I Trovato
Pim T Tuyls
Helen F Routh
Jeff Shimizu
Johan F Dijksman
Anke Pierik
Judith M Rensen
Hans Zou
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninkl Philips Electronics Nv, Karen I Trovato, Pim T Tuyls, Helen F Routh, Jeff Shimizu, Johan F Dijksman, Anke Pierik, Judith M Rensen, Hans Zou filed Critical Koninkl Philips Electronics Nv
Publication of WO2008120156A2 publication Critical patent/WO2008120156A2/en
Publication of WO2008120156A3 publication Critical patent/WO2008120156A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00002—Operational features of endoscopes
    • A61B1/00011—Operational features of endoscopes characterised by signal transmission
    • A61B1/00016—Operational features of endoscopes characterised by signal transmission using wireless means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00002—Operational features of endoscopes
    • A61B1/00059—Operational features of endoscopes provided with identification means for the endoscope
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • A61B1/041—Capsule endoscopes for imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0031—Implanted circuitry
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/08—Sensors provided with means for identification, e.g. barcodes or memory chips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/07—Endoradiosondes
    • A61B5/073—Intestinal transmitters
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04L—TRANSMISSION OF DIGITAL INFORMATION, e.g. TELEGRAPHIC COMMUNICATION
    • H04L63/00—Network architectures or network communication protocols for network security
    • H04L63/04—Network architectures or network communication protocols for network security for providing a confidential data exchange among entities communicating through data packet networks
    • H04L63/0428—Network architectures or network communication protocols for network security for providing a confidential data exchange among entities communicating through data packet networks wherein the data content is protected, e.g. by encrypting or encapsulating the payload
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04L—TRANSMISSION OF DIGITAL INFORMATION, e.g. TELEGRAPHIC COMMUNICATION
    • H04L63/00—Network architectures or network communication protocols for network security
    • H04L63/08—Network architectures or network communication protocols for network security for authentication of entities
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04L—TRANSMISSION OF DIGITAL INFORMATION, e.g. TELEGRAPHIC COMMUNICATION
    • H04L63/00—Network architectures or network communication protocols for network security
    • H04L63/10—Network architectures or network communication protocols for network security for controlling access to devices or network resources
    • H04L63/104—Grouping of entities

Abstract

A pill (10), associated parts; and method of operating the same, includes an ingestible shell (12), a medicine reservoir (14) or other treatment, sampling or sensing mechanism in the shell, a real-time clock for facilitating timed events, and a processor (26) in the shell. The processor is communication with a controller (16) for releasing medicine from the medicine reservoir or for performing other active functions for the pill. A pill memory is included for storing information about medicine released by the medicine reservoir such as dosage profile and timing profile, or other functions performed by the pill. A communicator (20) is also in the shell for receiving control signals for controlling the release controller and for transmitting the stored information from the pill memory. A tamper resistant bitstring contains identification information for uniquely identifying the pill and secret information for encrypting, decrypting, and authenticating communication via the communicator.
PCT/IB2008/051170 2007-03-30 2008-03-28 System and method for pill communication and control WO2008120156A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90914607P 2007-03-30 2007-03-30
US60/909,146 2007-03-30

Publications (2)

Publication Number Publication Date
WO2008120156A2 WO2008120156A2 (en) 2008-10-09
WO2008120156A3 true WO2008120156A3 (en) 2009-01-29

Family

ID=39618839

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/IB2008/051066 WO2008120128A2 (en) 2007-03-30 2008-03-20 System and method for pill communication and control
PCT/IB2008/051170 WO2008120156A2 (en) 2007-03-30 2008-03-28 System and method for pill communication and control

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PCT/IB2008/051066 WO2008120128A2 (en) 2007-03-30 2008-03-20 System and method for pill communication and control

Country Status (1)

Country Link
WO (2) WO2008120128A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7978064B2 (en) 2005-04-28 2011-07-12 Proteus Biomedical, Inc. Communication system with partial power source

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8730031B2 (en) 2005-04-28 2014-05-20 Proteus Digital Health, Inc. Communication system using an implantable device
US8912908B2 (en) 2005-04-28 2014-12-16 Proteus Digital Health, Inc. Communication system with remote activation
US8802183B2 (en) 2005-04-28 2014-08-12 Proteus Digital Health, Inc. Communication system with enhanced partial power source and method of manufacturing same
US8836513B2 (en) 2006-04-28 2014-09-16 Proteus Digital Health, Inc. Communication system incorporated in an ingestible product
US9198608B2 (en) 2005-04-28 2015-12-01 Proteus Digital Health, Inc. Communication system incorporated in a container
JP2009544338A (en) 2006-05-02 2009-12-17 プロテウス バイオメディカル インコーポレイテッド Treatment regimen customized to the patient
US8054140B2 (en) 2006-10-17 2011-11-08 Proteus Biomedical, Inc. Low voltage oscillator for medical devices
KR101611240B1 (en) 2006-10-25 2016-04-11 프로테우스 디지털 헬스, 인코포레이티드 Controlled activation ingestible identifier
WO2008063626A2 (en) 2006-11-20 2008-05-29 Proteus Biomedical, Inc. Active signal processing personal health signal receivers
MY165532A (en) 2007-02-01 2018-04-02 Proteus Digital Health Inc Ingestible event marker systems
EP2111661B1 (en) 2007-02-14 2017-04-12 Proteus Digital Health, Inc. In-body power source having high surface area electrode
EP2063771A1 (en) 2007-03-09 2009-06-03 Proteus Biomedical, Inc. In-body device having a deployable antenna
WO2008112577A1 (en) 2007-03-09 2008-09-18 Proteus Biomedical, Inc. In-body device having a multi-directional transmitter
US8540632B2 (en) 2007-05-24 2013-09-24 Proteus Digital Health, Inc. Low profile antenna for in body device
EP4011289A1 (en) 2007-09-25 2022-06-15 Otsuka Pharmaceutical Co., Ltd. In-body device with virtual dipole signal amplification
US20090135886A1 (en) 2007-11-27 2009-05-28 Proteus Biomedical, Inc. Transbody communication systems employing communication channels
JP2011513865A (en) 2008-03-05 2011-04-28 プロテウス バイオメディカル インコーポレイテッド Multi-mode communication ingestible event marker and system and method of using the same
WO2010005877A2 (en) 2008-07-08 2010-01-14 Proteus Biomedical, Inc. Ingestible event marker data framework
KR101214453B1 (en) 2008-08-13 2012-12-24 프로테우스 디지털 헬스, 인코포레이티드 Ingestible circuitry
KR101192690B1 (en) 2008-11-13 2012-10-19 프로테우스 디지털 헬스, 인코포레이티드 Ingestible therapy activator system, therapeutic device and method
US9659423B2 (en) 2008-12-15 2017-05-23 Proteus Digital Health, Inc. Personal authentication apparatus system and method
US9439566B2 (en) 2008-12-15 2016-09-13 Proteus Digital Health, Inc. Re-wearable wireless device
TWI503101B (en) 2008-12-15 2015-10-11 Proteus Digital Health Inc Body-associated receiver and method
WO2013012869A1 (en) 2011-07-21 2013-01-24 Proteus Digital Health, Inc. Mobile communication device, system, and method
EP3395333A1 (en) 2009-01-06 2018-10-31 Proteus Digital Health, Inc. Pharmaceutical dosages delivery system
CN102341031A (en) 2009-01-06 2012-02-01 普罗秋斯生物医学公司 Ingestion-related biofeedback and personalized medical therapy method and system
GB2480965B (en) 2009-03-25 2014-10-08 Proteus Digital Health Inc Probablistic pharmacokinetic and pharmacodynamic modeling
MX2011011506A (en) 2009-04-28 2012-05-08 Proteus Biomedical Inc Highly reliable ingestible event markers and methods for using the same.
US9149423B2 (en) 2009-05-12 2015-10-06 Proteus Digital Health, Inc. Ingestible event markers comprising an ingestible component
JP5006474B2 (en) * 2009-08-28 2012-08-22 オリンパスメディカルシステムズ株式会社 Receiving system
TWI517050B (en) 2009-11-04 2016-01-11 普羅托斯數位健康公司 System for supply chain management
AU2011210648B2 (en) 2010-02-01 2014-10-16 Otsuka Pharmaceutical Co., Ltd. Data gathering system
WO2011127252A2 (en) 2010-04-07 2011-10-13 Proteus Biomedical, Inc. Miniature ingestible device
TWI557672B (en) 2010-05-19 2016-11-11 波提亞斯數位康健公司 Computer system and computer-implemented method to track medication from manufacturer to a patient, apparatus and method for confirming delivery of medication to a patient, patient interface device
EP2642983A4 (en) 2010-11-22 2014-03-12 Proteus Digital Health Inc Ingestible device with pharmaceutical product
US9439599B2 (en) 2011-03-11 2016-09-13 Proteus Digital Health, Inc. Wearable personal body associated device with various physical configurations
JP5883699B2 (en) * 2011-04-13 2016-03-15 株式会社半導体エネルギー研究所 Programmable LSI
US20140228715A1 (en) * 2011-05-13 2014-08-14 The General Hospital Corporation Method and Apparatus for Delivering a Substance
WO2015112603A1 (en) 2014-01-21 2015-07-30 Proteus Digital Health, Inc. Masticable ingestible product and communication system therefor
US9756874B2 (en) 2011-07-11 2017-09-12 Proteus Digital Health, Inc. Masticable ingestible product and communication system therefor
US9235683B2 (en) 2011-11-09 2016-01-12 Proteus Digital Health, Inc. Apparatus, system, and method for managing adherence to a regimen
TW201424689A (en) 2012-07-23 2014-07-01 Proteus Digital Health Inc Techniques for manufacturing ingestible event markers comprising an ingestible component
US9131842B2 (en) 2012-08-16 2015-09-15 Rock West Solutions, Inc. System and methods for locating relative positions of multiple patient antennas
US10045713B2 (en) 2012-08-16 2018-08-14 Rock West Medical Devices, Llc System and methods for triggering a radiofrequency transceiver in the human body
US9268909B2 (en) 2012-10-18 2016-02-23 Proteus Digital Health, Inc. Apparatus, system, and method to adaptively optimize power dissipation and broadcast power in a power source for a communication device
US11149123B2 (en) 2013-01-29 2021-10-19 Otsuka Pharmaceutical Co., Ltd. Highly-swellable polymeric films and compositions comprising the same
US9319778B2 (en) 2013-03-13 2016-04-19 Google Inc. Communicating via a body-area network
JP6498177B2 (en) 2013-03-15 2019-04-10 プロテウス デジタル ヘルス， インコーポレイテッド Identity authentication system and method
US10175376B2 (en) 2013-03-15 2019-01-08 Proteus Digital Health, Inc. Metal detector apparatus, system, and method
JP6511439B2 (en) 2013-06-04 2019-05-15 プロテウス デジタル ヘルス， インコーポレイテッド Systems, devices, and methods for data collection and outcome assessment
US9796576B2 (en) 2013-08-30 2017-10-24 Proteus Digital Health, Inc. Container with electronically controlled interlock
MX356850B (en) 2013-09-20 2018-06-15 Proteus Digital Health Inc Methods, devices and systems for receiving and decoding a signal in the presence of noise using slices and warping.
US9577864B2 (en) 2013-09-24 2017-02-21 Proteus Digital Health, Inc. Method and apparatus for use with received electromagnetic signal at a frequency not known exactly in advance
AU2014340223B2 (en) 2013-10-22 2019-04-04 Rock West Medical Devices, Llc System to localize swallowable pill sensor with three transmitting elements
US10084880B2 (en) 2013-11-04 2018-09-25 Proteus Digital Health, Inc. Social media networking based on physiologic information
US9854437B1 (en) 2014-06-13 2017-12-26 Verily Life Sciences Llc Apparatus, system and method for exchanging encrypted communications with an eye-mountable device
US10704944B2 (en) 2014-09-14 2020-07-07 Becton, Dickinson And Company System and method for capturing dose information
US10971260B2 (en) 2014-09-14 2021-04-06 Becton, Dickinson And Company System and method for capturing dose information
US11051543B2 (en) 2015-07-21 2021-07-06 Otsuka Pharmaceutical Co. Ltd. Alginate on adhesive bilayer laminate film
CN109843149B (en) 2016-07-22 2020-07-07 普罗秋斯数字健康公司 Electromagnetic sensing and detection of ingestible event markers
JP2019535377A (en) 2016-10-26 2019-12-12 プロテウス デジタル ヘルス， インコーポレイテッド Method for producing capsules with ingestible event markers
WO2018175973A1 (en) * 2017-03-23 2018-09-27 Arizona Board Of Regents On Behalf Of Arizona State University Physical unclonable functions with copper-silicon oxide programmable metallization cells
US11244722B2 (en) 2019-09-20 2022-02-08 Arizona Board Of Regents On Behalf Of Arizona State University Programmable interposers for electrically connecting integrated circuits
US11935843B2 (en) 2019-12-09 2024-03-19 Arizona Board Of Regents On Behalf Of Arizona State University Physical unclonable functions with silicon-rich dielectric devices

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002067449A2 (en) * 2001-02-20 2002-08-29 Ellis Michael D Modular personal network systems and methods
US20040122315A1 (en) * 2002-09-24 2004-06-24 Krill Jerry A. Ingestible medical payload carrying capsule with wireless communication
WO2004105125A2 (en) * 2003-05-26 2004-12-02 Koninklijke Philips Electronics N.V. Semiconductor device, method of authentifying and system
WO2005114524A2 (en) * 2004-05-19 2005-12-01 Sensitron, Inc. Personalized remote patient monitoring systems and methods
WO2006021932A1 (en) * 2004-08-27 2006-03-02 Koninklijke Philips Electronics, N.V. Electronically and remotely controlled pill and system for delivering at least one medicament
US20070106269A1 (en) * 2005-11-09 2007-05-10 Hood Leroy E Remotely controlled substance delivery device

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002067449A2 (en) * 2001-02-20 2002-08-29 Ellis Michael D Modular personal network systems and methods
US20040122315A1 (en) * 2002-09-24 2004-06-24 Krill Jerry A. Ingestible medical payload carrying capsule with wireless communication
WO2004105125A2 (en) * 2003-05-26 2004-12-02 Koninklijke Philips Electronics N.V. Semiconductor device, method of authentifying and system
WO2005114524A2 (en) * 2004-05-19 2005-12-01 Sensitron, Inc. Personalized remote patient monitoring systems and methods
WO2006021932A1 (en) * 2004-08-27 2006-03-02 Koninklijke Philips Electronics, N.V. Electronically and remotely controlled pill and system for delivering at least one medicament
US20070106269A1 (en) * 2005-11-09 2007-05-10 Hood Leroy E Remotely controlled substance delivery device

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7978064B2 (en) 2005-04-28 2011-07-12 Proteus Biomedical, Inc. Communication system with partial power source

Also Published As

Publication number Publication date
WO2008120156A2 (en) 2008-10-09
WO2008120128A3 (en) 2009-01-08
WO2008120128A2 (en) 2008-10-09

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