WO2008088030A1 - 血栓もしくは塞栓に関連する疾患の予防又は治療用組成物 - Google Patents

血栓もしくは塞栓に関連する疾患の予防又は治療用組成物 Download PDF

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Publication number
WO2008088030A1
WO2008088030A1 PCT/JP2008/050554 JP2008050554W WO2008088030A1 WO 2008088030 A1 WO2008088030 A1 WO 2008088030A1 JP 2008050554 W JP2008050554 W JP 2008050554W WO 2008088030 A1 WO2008088030 A1 WO 2008088030A1
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WO
WIPO (PCT)
Prior art keywords
embolus
thrombus
prevention
treatment
composition
Prior art date
Application number
PCT/JP2008/050554
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English (en)
French (fr)
Inventor
Hiroyuki Kawano
Ryo Saito
Original Assignee
Mochida Pharmaceutical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mochida Pharmaceutical Co., Ltd. filed Critical Mochida Pharmaceutical Co., Ltd.
Priority to CA2675836A priority Critical patent/CA2675836C/en
Priority to EP08703408.8A priority patent/EP2119443B1/en
Priority to JP2008554086A priority patent/JP5345402B2/ja
Priority to US12/523,407 priority patent/US20100113506A1/en
Priority to ES08703408.8T priority patent/ES2524320T3/es
Publication of WO2008088030A1 publication Critical patent/WO2008088030A1/ja

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

　クロピドグレル、及びその製薬学上許容しうる塩からなる群から選ばれる少なくとも１つ、並びに、イコサペント酸、その製薬学上許容しうる塩およびエステルからなる群から選ばれる少なくとも１つを有効成分として併用する、血栓もしくは塞栓に関連する疾患の予防または治療用組成物を提供する。
PCT/JP2008/050554 2007-01-17 2008-01-17 血栓もしくは塞栓に関連する疾患の予防又は治療用組成物 WO2008088030A1 (ja)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CA2675836A CA2675836C (en) 2007-01-17 2008-01-17 Composition for preventing or treating thrombus- or embolus-associated disease
EP08703408.8A EP2119443B1 (en) 2007-01-17 2008-01-17 Composition for prevention or treatment of disease associated with thrombus or embolus
JP2008554086A JP5345402B2 (ja) 2007-01-17 2008-01-17 血栓もしくは塞栓に関連する疾患の予防又は治療用組成物
US12/523,407 US20100113506A1 (en) 2007-01-17 2008-01-17 Composition for preventing or treating thrombus- or embolus- associated disease
ES08703408.8T ES2524320T3 (es) 2007-01-17 2008-01-17 Composición para la prevención o el tratamiento de enfermedad asociada con trombo o émbolo

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007008590 2007-01-17
JP2007-008590 2007-01-17

Publications (1)

Publication Number Publication Date
WO2008088030A1 true WO2008088030A1 (ja) 2008-07-24

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/050554 WO2008088030A1 (ja) 2007-01-17 2008-01-17 血栓もしくは塞栓に関連する疾患の予防又は治療用組成物

Country Status (6)

Country Link
US (1) US20100113506A1 (ja)
EP (1) EP2119443B1 (ja)
JP (1) JP5345402B2 (ja)
CA (1) CA2675836C (ja)
ES (1) ES2524320T3 (ja)
WO (1) WO2008088030A1 (ja)

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WO2009087938A1 (ja) * 2008-01-10 2009-07-16 Takeda Pharmaceutical Company Limited カプセル製剤
WO2010021385A1 (ja) * 2008-08-22 2010-02-25 持田製薬株式会社 Ａｎｃａ関連血管炎治療薬
JP2012500385A (ja) * 2008-08-06 2012-01-05 インビトロックス，インコーポレイテッド 生物学的応用における集束光散乱技術の使用
WO2012067152A1 (ja) * 2010-11-16 2012-05-24 三菱化学株式会社 Endothelial Protein C Receptor蛋白質による脳梗塞の検査方法
JPWO2011065444A1 (ja) * 2009-11-27 2013-04-18 学校法人東海大学 抗血栓剤
WO2014003454A1 (en) * 2012-06-28 2014-01-03 Lg Life Sciences Ltd. Oral dosage form product of clopidogrel hydrogen sulfate with improved stability
JP2014531444A (ja) * 2011-09-15 2014-11-27 オムセラ・ファーマシューティカルズ・インコーポレイテッド 抗血小板療法に対する耐性を治療するか、逆転させるか、阻害するかまたは防止するための方法および組成物
JP2018521018A (ja) * 2015-06-03 2018-08-02 ウィスコンシン アラムニ リサーチ ファンデーション 虚血性疾患または虚血性損傷を処置するための心臓線維芽細胞由来細胞外マトリックスおよびその注射可能製剤
JP2020537696A (ja) * 2017-10-18 2020-12-24 高麗製薬株式会社Ｋｏｒｅａｎ Ｄｒｕｇ Ｃｏ．，Ｌｔｄ． 野せり抽出物および抗血栓剤を含む抗血栓用組成物

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US9662307B2 (en) 2013-02-19 2017-05-30 The Regents Of The University Of Colorado Compositions comprising eicosapentaenoic acid and a hydroxyl compound and methods of use thereof
US9283201B2 (en) 2013-03-14 2016-03-15 Amarin Pharmaceuticals Ireland Limited Compositions and methods for treating or preventing obesity in a subject in need thereof
US20140271841A1 (en) 2013-03-15 2014-09-18 Amarin Pharmaceuticals Ireland Limited Pharmaceutical composition comprising eicosapentaenoic acid and derivatives thereof and a statin
US10966968B2 (en) 2013-06-06 2021-04-06 Amarin Pharmaceuticals Ireland Limited Co-administration of rosiglitazone and eicosapentaenoic acid or a derivative thereof
US20150065572A1 (en) 2013-09-04 2015-03-05 Amarin Pharmaceuticals Ireland Limited Methods of treating or preventing prostate cancer
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Cited By (15)

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Publication number Priority date Publication date Assignee Title
WO2009087938A1 (ja) * 2008-01-10 2009-07-16 Takeda Pharmaceutical Company Limited カプセル製剤
JP2012500385A (ja) * 2008-08-06 2012-01-05 インビトロックス，インコーポレイテッド 生物学的応用における集束光散乱技術の使用
WO2010021385A1 (ja) * 2008-08-22 2010-02-25 持田製薬株式会社 Ａｎｃａ関連血管炎治療薬
EP2324827A1 (en) * 2008-08-22 2011-05-25 Mochida Pharmaceutical Co., Ltd. Therapeutic agent for anca-related vasculitis
JPWO2010021385A1 (ja) * 2008-08-22 2012-01-26 持田製薬株式会社 Ａｎｃａ関連血管炎治療薬
EP2324827A4 (en) * 2008-08-22 2012-04-25 Mochida Pharm Co Ltd THERAPEUTIC ACTIVE FOR ANCA-ASSOCIATED VASCULITIDES
JPWO2011065444A1 (ja) * 2009-11-27 2013-04-18 学校法人東海大学 抗血栓剤
WO2012067152A1 (ja) * 2010-11-16 2012-05-24 三菱化学株式会社 Endothelial Protein C Receptor蛋白質による脳梗塞の検査方法
JP2014531444A (ja) * 2011-09-15 2014-11-27 オムセラ・ファーマシューティカルズ・インコーポレイテッド 抗血小板療法に対する耐性を治療するか、逆転させるか、阻害するかまたは防止するための方法および組成物
WO2014003454A1 (en) * 2012-06-28 2014-01-03 Lg Life Sciences Ltd. Oral dosage form product of clopidogrel hydrogen sulfate with improved stability
JP2018521018A (ja) * 2015-06-03 2018-08-02 ウィスコンシン アラムニ リサーチ ファンデーション 虚血性疾患または虚血性損傷を処置するための心臓線維芽細胞由来細胞外マトリックスおよびその注射可能製剤
JP2022066207A (ja) * 2015-06-03 2022-04-28 ウィスコンシン アラムニ リサーチ ファンデーション 虚血性疾患または虚血性損傷を処置するための心臓線維芽細胞由来細胞外マトリックスおよびその注射可能製剤
JP2020537696A (ja) * 2017-10-18 2020-12-24 高麗製薬株式会社Ｋｏｒｅａｎ Ｄｒｕｇ Ｃｏ．，Ｌｔｄ． 野せり抽出物および抗血栓剤を含む抗血栓用組成物
JP2022062186A (ja) * 2017-10-18 2022-04-19 高麗製薬株式会社 野せり抽出物および抗血栓剤を含む抗血栓用組成物
JP7339698B2 (ja) 2017-10-18 2023-09-06 高麗製薬株式会社 野せり抽出物および抗血栓剤を含む抗血栓用組成物

Also Published As

Publication number Publication date
JP5345402B2 (ja) 2013-11-20
EP2119443A1 (en) 2009-11-18
JPWO2008088030A1 (ja) 2010-05-13
EP2119443A4 (en) 2010-03-03
US20100113506A1 (en) 2010-05-06
EP2119443B1 (en) 2014-08-20
ES2524320T3 (es) 2014-12-05
CA2675836A1 (en) 2008-07-24
CA2675836C (en) 2016-10-11

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