WO2007056522A3 - Remote controlled in vivo reaction method - Google Patents

Remote controlled in vivo reaction method Download PDF

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Publication number
WO2007056522A3
WO2007056522A3 PCT/US2006/043648 US2006043648W WO2007056522A3 WO 2007056522 A3 WO2007056522 A3 WO 2007056522A3 US 2006043648 W US2006043648 W US 2006043648W WO 2007056522 A3 WO2007056522 A3 WO 2007056522A3
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WO
WIPO (PCT)
Prior art keywords
reaction method
remote controlled
vivo reaction
environment
reaction device
Prior art date
Application number
PCT/US2006/043648
Other languages
French (fr)
Other versions
WO2007056522A2 (en
Inventor
Leroy E Hood
Muriel Y Ishikawa
Edward K Y Jung
Robert Langer
Clarence T Tegreene
Lowell L Wood Jr
Victoria Y H Wood
Original Assignee
Searete Llc
Leroy E Hood
Muriel Y Ishikawa
Edward K Y Jung
Robert Langer
Clarence T Tegreene
Lowell L Wood Jr
Victoria Y H Wood
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searete Llc, Leroy E Hood, Muriel Y Ishikawa, Edward K Y Jung, Robert Langer, Clarence T Tegreene, Lowell L Wood Jr, Victoria Y H Wood filed Critical Searete Llc
Priority to GB0809510A priority Critical patent/GB2446100B/en
Publication of WO2007056522A2 publication Critical patent/WO2007056522A2/en
Publication of WO2007056522A3 publication Critical patent/WO2007056522A3/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/172Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01GHORTICULTURE; CULTIVATION OF VEGETABLES, FLOWERS, RICE, FRUIT, VINES, HOPS OR SEAWEED; FORESTRY; WATERING
    • A01G7/00Botany in general
    • A01G7/06Treatment of growing trees or plants, e.g. for preventing decay of wood, for tingeing flowers or wood, for prolonging the life of plants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0097Micromachined devices; Microelectromechanical systems [MEMS]; Devices obtained by lithographic treatment of silicon; Devices comprising chips
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/14244Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14276Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
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    • A61M5/145Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0006Controlling or regulating processes
    • CCHEMISTRY; METALLURGY
    • C02TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02FTREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F1/00Treatment of water, waste water, or sewage
    • C02F1/008Control or steering systems not provided for elsewhere in subclass C02F
    • CCHEMISTRY; METALLURGY
    • C02TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02FTREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F1/00Treatment of water, waste water, or sewage
    • C02F1/02Treatment of water, waste water, or sewage by heating
    • CCHEMISTRY; METALLURGY
    • C02TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02FTREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F1/00Treatment of water, waste water, or sewage
    • C02F1/66Treatment of water, waste water, or sewage by neutralisation; pH adjustment
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N9/0004Oxidoreductases (1.)
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    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0006Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90Isomerases (5.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93Ligases (6)
    • GPHYSICS
    • G08SIGNALLING
    • G08CTRANSMISSION SYSTEMS FOR MEASURED VALUES, CONTROL OR SIMILAR SIGNALS
    • G08C17/00Arrangements for transmitting signals characterised by the use of a wireless electrical link
    • G08C17/02Arrangements for transmitting signals characterised by the use of a wireless electrical link using a radio link
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/145Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M2005/14513Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons with secondary fluid driving or regulating the infusion
    • AHUMAN NECESSITIES
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    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
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    • A61M2205/02General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0266Shape memory materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61M2205/02General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0272Electro-active or magneto-active materials
    • A61M2205/0288Electro-rheological or magneto-rheological materials
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    • A61M2205/3507Communication with implanted devices, e.g. external control
    • A61M2205/3523Communication with implanted devices, e.g. external control using telemetric means
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    • A61M2205/3569Range sublocal, e.g. between console and disposable
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    • A61M2205/36General characteristics of the apparatus related to heating or cooling
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/50General characteristics of the apparatus with microprocessors or computers
    • A61M2205/52General characteristics of the apparatus with microprocessors or computers with memories providing a history of measured variating parameters of apparatus or patient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
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    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/172Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
    • A61M5/1723Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure
    • BPERFORMING OPERATIONS; TRANSPORTING
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    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
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    • CCHEMISTRY; METALLURGY
    • C02TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02FTREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F2101/00Nature of the contaminant
    • C02F2101/10Inorganic compounds
    • C02F2101/20Heavy metals or heavy metal compounds
    • CCHEMISTRY; METALLURGY
    • C02TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02FTREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F2101/00Nature of the contaminant
    • C02F2101/30Organic compounds
    • C02F2101/36Organic compounds containing halogen
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    • CCHEMISTRY; METALLURGY
    • C02TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02FTREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F2209/00Controlling or monitoring parameters in water treatment
    • C02F2209/02Temperature

Abstract

Embodiments of a system including a remotely controlled reaction device and associated controller are described. Methods of use and control of the device are also disclosed. According to various embodiments, a reaction device is placed in an environment in order to perform a chemical reaction in an environment. Exemplary environments include a body of an organism, a body of water, or an enclosed volume of a fluid. In selected embodiments, a magnetic field, an electric field, or electromagnetic control 'signal may be used.
PCT/US2006/043648 2005-11-09 2006-11-09 Remote controlled in vivo reaction method WO2007056522A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB0809510A GB2446100B (en) 2005-11-09 2006-11-09 Remote controlled in vivo reaction method

Applications Claiming Priority (14)

Application Number Priority Date Filing Date Title
US11/270,799 2005-11-09
US11/272,455 2005-11-09
US11/272,455 US7817030B2 (en) 2005-11-09 2005-11-09 Remote controller for in situ reaction device
US11/271,146 US20070106275A1 (en) 2005-11-09 2005-11-09 Reaction device controlled by RF control signal
US11/272,524 2005-11-09
US11/272,573 2005-11-09
US11/271,145 US8585684B2 (en) 2005-11-09 2005-11-09 Reaction device controlled by magnetic control signal
US11/272,572 US9254256B2 (en) 2005-11-09 2005-11-09 Remote controlled in vivo reaction method
US11/270,799 US8998884B2 (en) 2005-11-09 2005-11-09 Remote controlled in situ reaction method
US11/271,146 2005-11-09
US11/271,145 2005-11-09
US11/272,524 US8617141B2 (en) 2005-11-09 2005-11-09 Remote controlled in situ reaction device
US11/272,572 2005-11-09
US11/272,573 US9474712B2 (en) 2005-11-09 2005-11-09 In situ reaction device

Publications (2)

Publication Number Publication Date
WO2007056522A2 WO2007056522A2 (en) 2007-05-18
WO2007056522A3 true WO2007056522A3 (en) 2007-11-22

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PCT/US2006/043676 WO2007056528A2 (en) 2005-11-09 2006-11-08 Remote controlled in situ reaction device
PCT/US2006/043648 WO2007056522A2 (en) 2005-11-09 2006-11-09 Remote controlled in vivo reaction method
PCT/US2006/043774 WO2007056565A2 (en) 2005-11-09 2006-11-09 Remote controlled in situ reaction method

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PCT/US2006/043676 WO2007056528A2 (en) 2005-11-09 2006-11-08 Remote controlled in situ reaction device

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PCT/US2006/043774 WO2007056565A2 (en) 2005-11-09 2006-11-09 Remote controlled in situ reaction method

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US (11) US9254256B2 (en)
GB (3) GB2446337B (en)
WO (3) WO2007056528A2 (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8083710B2 (en) 2006-03-09 2011-12-27 The Invention Science Fund I, Llc Acoustically controlled substance delivery device
US8273071B2 (en) * 2006-01-18 2012-09-25 The Invention Science Fund I, Llc Remote controller for substance delivery system
US9067047B2 (en) * 2005-11-09 2015-06-30 The Invention Science Fund I, Llc Injectable controlled release fluid delivery system
US8936590B2 (en) 2005-11-09 2015-01-20 The Invention Science Fund I, Llc Acoustically controlled reaction device
US9254256B2 (en) * 2005-11-09 2016-02-09 The Invention Science Fund I, Llc Remote controlled in vivo reaction method
US9028467B2 (en) * 2005-11-09 2015-05-12 The Invention Science Fund I, Llc Osmotic pump with remotely controlled osmotic pressure generation
US20070106271A1 (en) 2005-11-09 2007-05-10 Searete Llc, A Limited Liability Corporation Remote control of substance delivery system
US8992511B2 (en) * 2005-11-09 2015-03-31 The Invention Science Fund I, Llc Acoustically controlled substance delivery device
US20080140057A1 (en) 2006-03-09 2008-06-12 Searete Llc, A Limited Liability Corporation Of State Of The Delaware Injectable controlled release fluid delivery system
EP2341158B1 (en) * 2006-03-17 2014-10-08 University of Tsukuba Actuator and engine
WO2007108180A1 (en) * 2006-03-20 2007-09-27 University Of Tsukuba High-temperature shape memory alloy, actuator and motor
DE102006019419B4 (en) * 2006-04-26 2008-02-14 Siemens Ag Actuator, in particular an endo robot
US20070260174A1 (en) * 2006-05-05 2007-11-08 Searete Llc Detecting a failure to maintain a regimen
US20130226267A9 (en) * 2006-08-21 2013-08-29 Marom Bikson Method to reduce heating at implantable medical devices including neuroprosthetic devices
US8795721B2 (en) * 2006-12-18 2014-08-05 Eatlittle Inc. Device for delivery of a substance
US20110212163A1 (en) * 2008-07-24 2011-09-01 Children's Medical Center Corporation Magnetic heating for drug delivery and other applications
US20110212027A1 (en) * 2008-07-24 2011-09-01 Children's Medical Center Corporation Radiative heating for drug delivery and other applications
US20110230568A1 (en) * 2008-07-24 2011-09-22 Childrens Medical Center Corporation Heating of polymers and other materials using radiation for drug delivery and other applications
JP4722977B2 (en) * 2008-08-27 2011-07-13 シャープ株式会社 Detection instrument, analyzer, detection method, and control method of detection instrument
US8430831B2 (en) * 2009-02-25 2013-04-30 The Invention Science Fund I, Llc Device, system, and method for controllably reducing inflammatory mediators in a subject
US8424598B2 (en) 2010-09-21 2013-04-23 Halliburton Energy Services, Inc. Magnetically controlled delivery of subterranean fluid additives for use in subterranean applications
WO2012170068A2 (en) * 2011-06-05 2012-12-13 University Of British Columbia Wireless microactuators and control methods
US8643313B2 (en) * 2011-12-29 2014-02-04 General Electric Company Cyclotron actuator using a shape memory alloy
US10264972B2 (en) 2012-05-21 2019-04-23 International Business Machines Corporation Dispensing drugs from a companion diagnostic linked smart pill
TW201720462A (en) * 2015-12-08 2017-06-16 昱程科技股份有限公司 Biological carrier comprising a base layer, a positioning target and a foot
US11439747B2 (en) * 2017-10-04 2022-09-13 Purdue Research Foundation Drug delivery device and method
CA3088946A1 (en) 2018-01-11 2019-07-18 Shell Internationale Research Maatschappij B.V. Wireless monitoring and profiling of reactor conditions using arrays of sensor-enabled rfid tags placed at known reactor heights
US11383093B1 (en) 2019-12-06 2022-07-12 Hoseon LEE Radiation release capsule
CN114652960B (en) * 2022-03-22 2023-06-30 萧氏(东莞)电子科技有限公司 Split type massage waistband of removable oozing liquid medicine bullet

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6464687B1 (en) * 1999-03-09 2002-10-15 Ball Semiconductor, Inc. Implantable drug delivery system
US20040121486A1 (en) * 2002-08-16 2004-06-24 Uhland Scott A. Controlled release device and method using electrothermal ablation
US20050123563A1 (en) * 2003-07-30 2005-06-09 Doranz Benjamin J. Lipoparticles comprising proteins, methods of making, and using the same

Family Cites Families (242)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3760806A (en) 1971-01-13 1973-09-25 Alza Corp Helical osmotic dispenser with non-planar membrane
US3923426A (en) 1974-08-15 1975-12-02 Alza Corp Electroosmotic pump and fluid dispenser including same
US4053952A (en) 1975-10-10 1977-10-18 The United States Of America As Represented By The Secretary Of The Department Of Health, Education And Welfare Magnetic fluid actuated control valve, relief valve and pump
US4089209A (en) * 1977-08-04 1978-05-16 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Remote water monitoring system
US4221219A (en) * 1978-07-31 1980-09-09 Metal Bellows Corporation Implantable infusion apparatus and method
US4263910A (en) 1978-09-27 1981-04-28 Eli Lilly And Company Implantate package, system and method
US4360019A (en) 1979-02-28 1982-11-23 Andros Incorporated Implantable infusion device
US4373527B1 (en) 1979-04-27 1995-06-27 Univ Johns Hopkins Implantable programmable medication infusion system
US4692147A (en) 1980-04-02 1987-09-08 Medtronic, Inc. Drug administration device
US4412148A (en) * 1981-04-24 1983-10-25 The United States Of America As Represented By The Secretary Of The Navy PZT Composite and a fabrication method thereof
US4811279A (en) * 1981-10-05 1989-03-07 Digital Equipment Corporation Secondary storage facility employing serial communications between drive and controller
US4457752A (en) * 1982-09-13 1984-07-03 Csaba Vadasz Surgically implantable pump
US4753636A (en) 1983-08-02 1988-06-28 Endocon, Inc. Subcutaneous implant kit
JPS60118289A (en) 1983-11-30 1985-06-25 Giken Kogyo Kk Water purifying method
GR851195B (en) 1984-06-02 1985-11-25 Castex Prod
US4513034A (en) * 1984-06-14 1985-04-23 Merck & Co., Inc. Variable permeability liquid crystalline membranes
US4779806A (en) 1984-07-23 1988-10-25 Massachusetts Institute Of Technology Ultrasonically modulated polymeric devices for delivering compositions
US4579837A (en) * 1984-10-22 1986-04-01 Kms Fusion, Inc. Solid phase photosensitizer for generation of singlet oxygen
US4952406A (en) 1985-06-27 1990-08-28 The Children's Medical Center Corporation Feedback controlled release
US4714462A (en) 1986-02-03 1987-12-22 Intermedics Infusaid, Inc. Positive pressure programmable infusion pump
US5019372A (en) * 1986-06-27 1991-05-28 The Children's Medical Center Corporation Magnetically modulated polymeric drug release system
GB8701731D0 (en) 1987-01-27 1987-03-04 Patcentre Benelux Nv Sa Pumps
US4883666A (en) 1987-04-29 1989-11-28 Massachusetts Institute Of Technology Controlled drug delivery system for treatment of neural disorders
US4787888A (en) * 1987-06-01 1988-11-29 University Of Connecticut Disposable piezoelectric polymer bandage for percutaneous delivery of drugs and method for such percutaneous delivery (a)
US4861484A (en) 1988-03-02 1989-08-29 Synlize, Inc. Catalytic process for degradation of organic materials in aqueous and organic fluids to produce environmentally compatible products
US4834704A (en) * 1988-04-13 1989-05-30 Eaton Corporation Injectable infusion pump apparatus for implanting long-term dispensing module and medication in an animal and method therefor
US4929233A (en) 1988-08-26 1990-05-29 Alza Corporation Implantable fluid imbibing pump with improved closure
US5612059A (en) 1988-08-30 1997-03-18 Pfizer Inc. Use of asymmetric membranes in delivery devices
US5222362A (en) * 1989-01-10 1993-06-29 Maus Daryl D Heat-activated drug delivery system and thermal actuators therefor
GB8913450D0 (en) * 1989-06-12 1989-08-02 Philips Electronic Associated Electrical device manufacture,particularly infrared detector arrays
US5580575A (en) * 1989-12-22 1996-12-03 Imarx Pharmaceutical Corp. Therapeutic drug delivery systems
US5045082A (en) 1990-01-10 1991-09-03 Alza Corporation Long-term delivery device including loading dose
US5049141A (en) 1990-04-25 1991-09-17 Infusaid, Inc. Programmable valve pump
US5170801A (en) 1990-10-02 1992-12-15 Glaxo Inc. Medical capsule device actuated by radio-frequency (rf) signal
US5167625A (en) 1990-10-09 1992-12-01 Sarcos Group Multiple vesicle implantable drug delivery system
US5059175A (en) 1990-10-09 1991-10-22 University Of Utah Research Foundation Implantable drug delivery system with piston actuation
US5217449A (en) 1990-12-11 1993-06-08 Miyarisan Kabushiki Kaisha Medical capsule and apparatus for activating the same
FI91261C (en) * 1991-03-22 1996-01-31 Xyrofin Oy Crystalline, anhydrous lactitol and method for its preparation and use
US5391164A (en) * 1991-05-03 1995-02-21 Giampapa; Vincent C. Subcutaneous implantable multiple-agent delivery system
US5395366A (en) 1991-05-30 1995-03-07 The State University Of New York Sampling capsule and process
US5279607A (en) * 1991-05-30 1994-01-18 The State University Of New York Telemetry capsule and process
NL9101197A (en) 1991-07-08 1993-02-01 Texas Instruments Holland INJECTOR.
US5207666A (en) * 1991-08-30 1993-05-04 Infusaid, Inc. Passive shuttle metering device for implantable drug delivery system
ATE198159T1 (en) * 1992-10-15 2001-01-15 Gen Hospital Corp INFUSION PUMP WITH ELECTRONICALLY LOADABLE MEDICATION LIBRARY
US5370672A (en) 1992-10-30 1994-12-06 The Johns Hopkins University Computer-controlled neurological stimulation system
US6152181A (en) 1992-11-16 2000-11-28 The United States Of America As Represented By The Secretary Of The Air Force Microdevices based on surface tension and wettability that function as sensors, actuators, and other devices
US5290240A (en) 1993-02-03 1994-03-01 Pharmetrix Corporation Electrochemical controlled dispensing assembly and method for selective and controlled delivery of a dispensing fluid
US6413949B1 (en) 1995-06-07 2002-07-02 D-Pharm, Ltd. Prodrugs with enhanced penetration into cells
US5666977A (en) 1993-06-10 1997-09-16 Philip Morris Incorporated Electrical smoking article using liquid tobacco flavor medium delivery system
DE4334247B4 (en) 1993-10-08 2006-11-02 Codman Neuro Sciences Sàrl A method of adjusting a switchable flow restricting device and a device operating according to the method
US5814599A (en) 1995-08-04 1998-09-29 Massachusetts Insitiute Of Technology Transdermal delivery of encapsulated drugs
US5484403A (en) 1994-04-05 1996-01-16 Avid Marketing, Inc. Hypodermic syringe for implanting solid objects
US5523746A (en) * 1994-09-01 1996-06-04 Gallagher; Robert R. Identification system with a passive activator
CA2202552A1 (en) * 1994-10-13 1996-04-25 John J. Palmer Defoamer composition and method of using the same
IE72524B1 (en) * 1994-11-04 1997-04-23 Elan Med Tech Analyte-controlled liquid delivery device and analyte monitor
US5644177A (en) 1995-02-23 1997-07-01 Wisconsin Alumni Research Foundation Micromechanical magnetically actuated devices
US5643246A (en) 1995-02-24 1997-07-01 Gel Sciences, Inc. Electromagnetically triggered, responsive gel based drug delivery device
DE820258T1 (en) 1995-03-23 1998-04-30 Advanced Animal Technology Ltd SUBSTANCE DELIVERY DEVICE
US5651979A (en) 1995-03-30 1997-07-29 Gel Sciences, Inc. Apparatus and method for delivering a biologically active compound into a biological environment
US5856174A (en) 1995-06-29 1999-01-05 Affymetrix, Inc. Integrated nucleic acid diagnostic device
US5995860A (en) 1995-07-06 1999-11-30 Thomas Jefferson University Implantable sensor and system for measurement and control of blood constituent levels
US6041253A (en) 1995-12-18 2000-03-21 Massachusetts Institute Of Technology Effect of electric field and ultrasound for transdermal drug delivery
US6245347B1 (en) 1995-07-28 2001-06-12 Zars, Inc. Methods and apparatus for improved administration of pharmaceutically active compounds
CH689754A5 (en) * 1995-07-31 1999-10-15 Lough J Ltd Machine for the realization of the coffee type beverages expressed with automatic introduction of the coffee powder and expulsion of the funds.
US20040115128A1 (en) 1995-09-08 2004-06-17 Schnitzer Jan E. Targeting endothelium for tissue-specific delivery of agents
US6048734A (en) * 1995-09-15 2000-04-11 The Regents Of The University Of Michigan Thermal microvalves in a fluid flow method
US5719296A (en) * 1995-10-30 1998-02-17 Merck & Co., Inc. Pseudopeptide lactam inhibitors of peptide binding to MHC class II proteins
AU2260397A (en) * 1996-01-31 1997-08-22 Trustees Of The University Of Pennsylvania, The Remote control drug delivery device
US6395292B2 (en) * 1996-02-02 2002-05-28 Alza Corporation Sustained delivery of an active agent using an implantable system
US6261584B1 (en) 1996-02-02 2001-07-17 Alza Corporation Sustained delivery of an active agent using an implantable system
IL125758A (en) 1996-02-15 2003-07-06 Biosense Inc Medical probes with field transducers
US5655539A (en) * 1996-02-26 1997-08-12 Abbott Laboratories Method for conducting an ultrasound procedure using an ultrasound transmissive pad
US5869078A (en) * 1996-04-25 1999-02-09 Medtronic Inc. Implantable variable permeability drug infusion techniques
US5797898A (en) 1996-07-02 1998-08-25 Massachusetts Institute Of Technology Microchip drug delivery devices
US7070590B1 (en) 1996-07-02 2006-07-04 Massachusetts Institute Of Technology Microchip drug delivery devices
US5733313A (en) 1996-08-01 1998-03-31 Exonix Corporation RF coupled, implantable medical device with rechargeable back-up power source
US6544193B2 (en) * 1996-09-04 2003-04-08 Marcio Marc Abreu Noninvasive measurement of chemical substances
US6120460A (en) 1996-09-04 2000-09-19 Abreu; Marcio Marc Method and apparatus for signal acquisition, processing and transmission for evaluation of bodily functions
US5879329A (en) * 1997-01-22 1999-03-09 Radiant Medical, Inc. Infusion systems and methods for introducing fluids into the body within a desired temperature range
US20060089751A1 (en) * 1997-01-27 2006-04-27 Ewa Herbst Electronic delivery systems and methods with feedback
US6086582A (en) 1997-03-13 2000-07-11 Altman; Peter A. Cardiac drug delivery system
US5827186A (en) 1997-04-11 1998-10-27 Light Sciences Limited Partnership Method and PDT probe for minimizing CT and MRI image artifacts
US6272370B1 (en) 1998-08-07 2001-08-07 The Regents Of University Of Minnesota MR-visible medical device for neurological interventions using nonlinear magnetic stereotaxis and a method imaging
US6116863A (en) 1997-05-30 2000-09-12 University Of Cincinnati Electromagnetically driven microactuated device and method of making the same
US6339897B1 (en) * 1997-07-08 2002-01-22 Microfab Technologies, Inc. Method and apparatus for dispensing airborne materials for controlling pests
US6585763B1 (en) 1997-10-14 2003-07-01 Vascusense, Inc. Implantable therapeutic device and method
US6238555B1 (en) 1997-11-07 2001-05-29 Bioquest Amperometric halogen control system
US20030036746A1 (en) 2001-08-16 2003-02-20 Avi Penner Devices for intrabody delivery of molecules and systems and methods utilizing same
US6203523B1 (en) 1998-02-02 2001-03-20 Medtronic Inc Implantable drug infusion device having a flow regulator
US6048328A (en) * 1998-02-02 2000-04-11 Medtronic, Inc. Implantable drug infusion device having an improved valve
US6246241B1 (en) 1998-02-06 2001-06-12 Siemens Energy & Automation, Inc. Testing of bimetallic actuators with radio frequency induction heating
US5945762A (en) 1998-02-10 1999-08-31 Light Sciences Limited Partnership Movable magnet transmitter for inducing electrical current in an implanted coil
DK1062278T3 (en) * 1998-02-23 2006-09-25 Mnemoscience Gmbh Polymers with shape memory
DE19811017A1 (en) * 1998-03-13 1999-09-16 Dade Behring Marburg Gmbh New method for the determination of plasma proteins and factors of hemostasis as well as a new, implantable measuring device
WO1999052586A1 (en) * 1998-04-13 1999-10-21 Cytotherapeutics, Inc. Tether anchor
US5993414A (en) 1998-04-23 1999-11-30 Medtronic, Inc. Implantable device
US6206914B1 (en) * 1998-04-30 2001-03-27 Medtronic, Inc. Implantable system with drug-eluting cells for on-demand local drug delivery
US20040076559A1 (en) 1998-08-05 2004-04-22 Franz Brucker Device and method for the production of singlet oxygen
CN1322282A (en) 1998-09-03 2001-11-14 卢卡斯新星传感器公司 Proportional micromechanical device
US6146103A (en) 1998-10-09 2000-11-14 The Regents Of The University Of California Micromachined magnetohydrodynamic actuators and sensors
EP1125121B1 (en) 1998-10-28 2007-12-12 Covaris, Inc. Apparatus and methods for controlling sonic treatment
US6948843B2 (en) * 1998-10-28 2005-09-27 Covaris, Inc. Method and apparatus for acoustically controlling liquid solutions in microfluidic devices
US6500165B1 (en) 1998-10-29 2002-12-31 Steven R. Frank Active antisepsis device
FR2792234B1 (en) * 1999-04-15 2001-06-01 Lorraine Laminage TREATMENT TO IMPROVE THE CASABILITY OF CALM STEEL WITH CONTINUOUS CAST ALUMINUM
RU2154848C1 (en) * 1999-04-21 2000-08-20 Государственное унитарное предприятие Научно-производственное предприятие "Полет" Automatic station of identification of pollution of water objects
US6554822B1 (en) * 1999-04-30 2003-04-29 University Of Southern California Microbolus infusion pump
US6796956B2 (en) 1999-04-30 2004-09-28 Medtronic, Inc. Method and apparatus to control drug therapy dosages in an implantable pump
US6475750B1 (en) 1999-05-11 2002-11-05 M-Biotech, Inc. Glucose biosensor
DK1065378T3 (en) 1999-06-28 2002-07-29 California Inst Of Techn Elastomeric micropump and micro valve systems
US6962170B1 (en) 1999-07-30 2005-11-08 The Procter & Gamble Company Microvalve for controlling fluid flow
CA2381951A1 (en) 1999-08-18 2001-02-22 Microchips, Inc. Thermally-activated microchip chemical delivery devices
US6802811B1 (en) 1999-09-17 2004-10-12 Endoluminal Therapeutics, Inc. Sensing, interrogating, storing, telemetering and responding medical implants
US6638263B1 (en) * 1999-10-12 2003-10-28 Durect Corporation Regulation of drug delivery through flow diversion
WO2001035928A1 (en) * 1999-11-17 2001-05-25 Microchips, Inc. Microfabricated devices for the delivery of molecules into a carrier fluid
AU782639B2 (en) 1999-12-10 2005-08-18 Massachusetts Institute Of Technology Microchip devices for delivery of molecules and methods of fabrication thereof
US6589205B1 (en) 1999-12-17 2003-07-08 Advanced Bionica Corporation Externally-controllable constant-flow medication delivery system
GB9930000D0 (en) 1999-12-21 2000-02-09 Phaeton Research Ltd An ingestible device
IL134009A (en) 2000-01-12 2011-07-31 Bo2 Technologies Ltd Implantable device
US6733446B2 (en) 2000-01-21 2004-05-11 Medtronic Minimed, Inc. Ambulatory medical apparatus and method using a telemetry system with predefined reception listening periods
US6458118B1 (en) 2000-02-23 2002-10-01 Medtronic, Inc. Drug delivery through microencapsulation
US6491061B1 (en) 2000-02-25 2002-12-10 University Of New Mexico Stimuli responsive hybrid materials containing molecular actuators and their applications
US6454759B2 (en) 2000-02-28 2002-09-24 The Regents Of The University Of California Microfabricated injectable drug delivery system
JP3960802B2 (en) * 2000-03-02 2007-08-15 マイクロチップス・インコーポレーテッド Microfabricated devices for storing and selectively exposing chemicals and devices
US6565526B2 (en) 2000-03-09 2003-05-20 The Regents Of The University Of California Bistable microvalve and microcatheter system
US6569152B2 (en) 2000-03-21 2003-05-27 Farrington Pharmaceuticals, Llc Sustained release delivery systems for solutes
US6682521B2 (en) * 2000-03-23 2004-01-27 Dennis N. Petrakis Temperature activated systems
US6757558B2 (en) * 2000-07-06 2004-06-29 Algodyne, Ltd. Objective pain measurement system and method
US7004184B2 (en) * 2000-07-24 2006-02-28 The Reagents Of The University Of Michigan Compositions and methods for liquid metering in microchannels
DE10041221A1 (en) * 2000-08-22 2002-03-14 Deutsches Krebsforsch Process for the preparation of water-soluble saccharide conjugates and saccharide mimetics by the Diels-Alder reaction and their use as therapeutics or diagnostics
US6590267B1 (en) 2000-09-14 2003-07-08 Mcnc Microelectromechanical flexible membrane electrostatic valve device and related fabrication methods
US6845267B2 (en) 2000-09-28 2005-01-18 Advanced Bionics Corporation Systems and methods for modulation of circulatory perfusion by electrical and/or drug stimulation
DE10048153A1 (en) 2000-09-28 2002-04-25 Natural Energy Solutions Ag Device for generating singlet oxygen
US7348182B2 (en) * 2000-10-03 2008-03-25 Mirari Biosciences, Inc. Directed microwave chemistry
US7258774B2 (en) 2000-10-03 2007-08-21 California Institute Of Technology Microfluidic devices and methods of use
WO2002030264A2 (en) * 2000-10-10 2002-04-18 Microchips, Inc. Microchip reservoir devices using wireless transmission of power and data
US6416495B1 (en) 2000-10-10 2002-07-09 Science Incorporated Implantable fluid delivery device for basal and bolus delivery of medicinal fluids
WO2002030401A2 (en) 2000-10-11 2002-04-18 Microchips, Inc. Microchip reservoir devices and facilitated corrosion of electrodes
US7198603B2 (en) 2003-04-14 2007-04-03 Remon Medical Technologies, Inc. Apparatus and methods using acoustic telemetry for intrabody communications
US7024248B2 (en) * 2000-10-16 2006-04-04 Remon Medical Technologies Ltd Systems and methods for communicating with implantable devices
US6628989B1 (en) 2000-10-16 2003-09-30 Remon Medical Technologies, Ltd. Acoustic switch and apparatus and methods for using acoustic switches within a body
US6929636B1 (en) 2000-11-08 2005-08-16 Hewlett-Packard Development Company, L.P. Internal drug dispenser capsule medical device
US6653124B1 (en) 2000-11-10 2003-11-25 Cytoplex Biosciences Inc. Array-based microenvironment for cell culturing, cell monitoring and drug-target validation
US6607553B1 (en) 2000-11-17 2003-08-19 B. Braun Medical, Inc. Method for deploying a thermo-mechanically expandable stent
EP1341476A2 (en) 2000-12-01 2003-09-10 Nephros Therapeutics, Inc. Intrasvascular drug delivery device and use therefor
US6805783B2 (en) 2000-12-13 2004-10-19 Toyo Technologies, Inc. Method for manipulating a solution using a ferroelectric electro-osmotic pump
EP1347705B1 (en) 2000-12-21 2005-12-07 Insulet Corporation Medical apparatus remote control
ATE369817T1 (en) 2000-12-22 2007-09-15 Avantec Vascular Corp DEVICE FOR DELIVERING THERAPEUTIC ACTIVE INGREDIENTS
GB0102171D0 (en) 2001-01-27 2001-03-14 Krumme John A drug delivery service
US7776029B2 (en) 2001-01-30 2010-08-17 The Alfred E. Mann Foundation For Scientific Research Microminiature infusion pump
US6511473B2 (en) * 2001-01-30 2003-01-28 Biodepo, Inc. Implantable bioartificial active secretion system
US6562000B2 (en) * 2001-02-02 2003-05-13 Medtronic, Inc. Single-use therapeutic substance delivery device with infusion rate control
US6571125B2 (en) * 2001-02-12 2003-05-27 Medtronic, Inc. Drug delivery device
US20020188323A1 (en) 2001-03-19 2002-12-12 Remon Medical Technologies Ltd. Methods, systems and devices for in vivo electrochemical production of therapeutic agents
US7201746B2 (en) 2001-04-10 2007-04-10 Medtronic, Inc. Implantable therapeutic substance delivery device having a piston pump with an anti-cavitation valve
US7288085B2 (en) 2001-04-10 2007-10-30 Medtronic, Inc. Permanent magnet solenoid pump for an implantable therapeutic substance delivery device
US7083593B2 (en) 2001-04-18 2006-08-01 Advanced Bionics Corporation Programmable implantable pump with accessory reservoirs and multiple independent lumen catheter
US20040015154A1 (en) 2001-04-19 2004-01-22 Microsolutions, Inc. Implantable devices with invasive and non-invasive reversible infusion rate adjustability
US6635837B2 (en) 2001-04-26 2003-10-21 Adc Telecommunications, Inc. MEMS micro-relay with coupled electrostatic and electromagnetic actuation
US7563255B2 (en) * 2001-05-03 2009-07-21 Massachusetts Eye And Ear Infirmary Implantable drug delivery device and use thereof
WO2002091028A2 (en) 2001-05-03 2002-11-14 Colorado School Of Mines Devices employing colloidal-sized particles
US6723086B2 (en) 2001-05-07 2004-04-20 Logiq Wireless Solutions, Inc. Remote controlled transdermal medication delivery device
US6491684B1 (en) 2001-05-22 2002-12-10 Durect Corporation Fluid delivery device having a water generating electrochemical/chemical pump and associated method
US6844028B2 (en) * 2001-06-26 2005-01-18 Accelr8 Technology Corporation Functional surface coating
US7044911B2 (en) 2001-06-29 2006-05-16 Philometron, Inc. Gateway platform for biological monitoring and delivery of therapeutic compounds
US20030015768A1 (en) * 2001-07-23 2003-01-23 Motorola, Inc. Structure and method for microelectromechanical system (MEMS) devices integrated with other semiconductor structures
US6970741B1 (en) 2001-09-18 2005-11-29 Advanced Bionics Corporation Monitoring, preventing, and treating rejection of transplanted organs
AU2002334708A1 (en) 2001-10-01 2003-04-14 Kline And Walker, Llc Pfn/trac system faa upgrades for accountable remote and robotics control
US6648457B2 (en) * 2001-10-31 2003-11-18 Hewlett-Packard Development Company, L.P. Redundant fluid interconnect seal for a modular ink jet delivery system
US7020355B2 (en) 2001-11-02 2006-03-28 Massachusetts Institute Of Technology Switchable surfaces
US20030147812A1 (en) 2001-12-11 2003-08-07 Friedrich Ueberle Device and methods for initiating chemical reactions and for the targeted delivery of drugs or other agents
AU2002360670A1 (en) 2001-12-19 2003-07-09 Wilk Patent Development Corporation Method and related composition employing nanostructures
US6755789B2 (en) * 2002-02-05 2004-06-29 Inceptio Medical Technologies, Llc Ultrasonic vascular imaging system and method of blood vessel cannulation
US6852104B2 (en) 2002-02-28 2005-02-08 Smiths Medical Md, Inc. Programmable insulin pump
US6692457B2 (en) * 2002-03-01 2004-02-17 Insulet Corporation Flow condition sensor assembly for patient infusion device
US20030171738A1 (en) 2002-03-06 2003-09-11 Konieczynski David D. Convection-enhanced drug delivery device and method of use
AU2003223244A1 (en) * 2002-03-11 2003-09-29 The Johns Hopkins University Molecular switches and methods for making and using the same
EP1490887A2 (en) * 2002-03-20 2004-12-29 Purdue Research Foundation Microscale sensor element and related device and method of manufacture
US8849379B2 (en) 2002-04-22 2014-09-30 Geelux Holdings, Ltd. Apparatus and method for measuring biologic parameters
GB2389791B (en) 2002-04-30 2006-12-13 Steven Gill Implantable drug delivery pump
US7896867B2 (en) 2002-05-01 2011-03-01 Microlin, Llc Fluid delivery device having an electrochemical pump with an ion-exchange membrane and associated method
US6933660B2 (en) * 2002-06-06 2005-08-23 Caterpillar Inc Piezoelectric bender with increased activating force, and valve using same
US7753656B2 (en) 2002-06-20 2010-07-13 Lawrence Livermore National Security, Llc Magnetohydrodynamic pump with a system for promoting flow of fluid in one direction
US6780320B2 (en) 2002-06-20 2004-08-24 The Regents Of The University Of California Magnetohydrodynamic fluidic system
EP1520201B1 (en) 2002-07-04 2014-04-23 Micronic Mydata AB Method for controlling deformable actuators
US7390310B2 (en) * 2002-07-10 2008-06-24 Codman & Shurtleff, Inc. Shunt valve locking mechanism
US20040025639A1 (en) * 2002-08-09 2004-02-12 Dr. Mohsen Shahinpoor Novel electrically active ionic polymer metal composites and novel methods of manufacturing them
KR100473523B1 (en) * 2002-08-22 2005-03-08 한국과학기술원 Micropower devices
US20040049245A1 (en) 2002-09-09 2004-03-11 Volker Gass Autonomous patch for communication with an implantable device, and medical kit for using said patch
US6880564B2 (en) * 2002-09-20 2005-04-19 Advanced Neuromodulation Systems, Inc. Dosage control apparatus
US7534241B2 (en) * 2002-09-23 2009-05-19 Microchips, Inc. Micro-reservoir osmotic release systems and microtube array device
US7118531B2 (en) 2002-09-24 2006-10-10 The Johns Hopkins University Ingestible medical payload carrying capsule with wireless communication
US20040073221A1 (en) 2002-10-11 2004-04-15 Spineco, Inc., A Corporation Of Ohio Electro-stimulation and medical delivery device
WO2004036059A1 (en) * 2002-10-16 2004-04-29 Matsushita Electric Industrial Co. Ltd. Valve unit and fluid control chip
US7474180B2 (en) 2002-11-01 2009-01-06 Georgia Tech Research Corp. Single substrate electromagnetic actuator
US7195036B2 (en) 2002-11-04 2007-03-27 The Regents Of The University Of Michigan Thermal micro-valves for micro-integrated devices
US7159841B2 (en) 2002-11-07 2007-01-09 The United States Of America As Represented By The United States Department Of Energy Piezoelectric axial flow microvalve
EP1572287B1 (en) 2002-12-02 2011-02-23 Med-El Elektromedizinische Geräte GmbH Fluid switch controlled trans-cutaneously via a magnetic force
US6981849B2 (en) * 2002-12-18 2006-01-03 Intel Corporation Electro-osmotic pumps and micro-channels
US20040230182A1 (en) 2002-12-27 2004-11-18 Medtronic, Inc. Drug delivery through encapsulation
EP1605985A2 (en) 2003-01-12 2005-12-21 Odontonanotek, Inc. Implantable interface system
CN1774577B (en) * 2003-02-24 2011-06-08 马克·巴尼斯特 Pulse activated actuator pump system
US7824444B2 (en) 2003-03-20 2010-11-02 Spineco, Inc. Expandable spherical spinal implant
US20040186373A1 (en) 2003-03-21 2004-09-23 Dunfield John Stephen Method and device for targeted epithelial delivery of medicinal and related agents
US20050234431A1 (en) * 2004-02-10 2005-10-20 Williams Michael S Intravascular delivery system for therapeutic agents
US7727969B2 (en) 2003-06-06 2010-06-01 Massachusetts Institute Of Technology Controlled release nanoparticle having bound oligonucleotide for targeted delivery
WO2005007223A2 (en) 2003-07-16 2005-01-27 Sasha John Programmable medical drug delivery systems and methods for delivery of multiple fluids and concentrations
US20050055014A1 (en) * 2003-08-04 2005-03-10 Coppeta Jonathan R. Methods for accelerated release of material from a reservoir device
US7315109B1 (en) * 2003-08-15 2008-01-01 Medrad, Inc. Actuators and fluid delivery systems using such actuators
US7214190B1 (en) 2003-09-09 2007-05-08 Kitchener Clark Wilson Apparatus and method for noninvasive monitoring of analytes in body fluids
FR2860438B1 (en) * 2003-10-07 2006-06-02 Jean Marie Podvin IMPLANTABLE PERFUSION DEVICE
EP1685257A4 (en) * 2003-10-29 2008-07-23 Agency Science Tech & Res Method for detecting analytes by means of an analyte/polymeric activator bilayer arrangement
ATE482650T1 (en) 2003-11-03 2010-10-15 Microchips Inc MEDICAL DEVICE FOR MEASURING GLUCOSE
US7377939B2 (en) * 2003-11-19 2008-05-27 Synecor, Llc Highly convertible endolumenal prostheses and methods of manufacture
US20050187515A1 (en) 2004-02-19 2005-08-25 Advanced Neuromodulation Systems, Inc. Reduced size programmable drug pump
US20050191194A1 (en) 2004-02-26 2005-09-01 Falk Theodore J. Low power electromagnetic pump having internal compliant element
US7840263B2 (en) 2004-02-27 2010-11-23 Cardiac Pacemakers, Inc. Method and apparatus for device controlled gene expression
EP1725219B1 (en) 2004-03-02 2009-12-09 Infusion Systems, LLC Apparatus for automatically modifying delivery profile of drug delivery system
JP2008501037A (en) * 2004-06-01 2008-01-17 マイクロチップス・インコーポレーテッド Devices and methods for measuring and enhancing transport of drugs or analytes to / from medical implants
US20060004417A1 (en) * 2004-06-30 2006-01-05 Cvrx, Inc. Baroreflex activation for arrhythmia treatment
US7305824B1 (en) * 2004-08-06 2007-12-11 Hrl Laboratories, Llc Power-off hold element
JP2006084860A (en) * 2004-09-16 2006-03-30 Sharp Corp Driving method of liquid crystal display, and the liquid crystal display
US7422892B2 (en) * 2004-10-06 2008-09-09 Agentase, Llc Enzyme-based device for environmental monitoring
EP1652497B3 (en) * 2004-10-27 2012-02-15 Ostomycure AS Adapter, lid and connector for ostomy bags
US20060149321A1 (en) 2004-12-30 2006-07-06 Merry Randy L Medical device information system
WO2006078943A2 (en) 2005-01-19 2006-07-27 Micro Beef Technologies, Ltd. Method and system for tracking and managing animals and/or food products
BRPI0606982A2 (en) * 2005-02-01 2009-07-28 Baxter Int infusion delivery system
US7357815B2 (en) 2005-04-21 2008-04-15 Micardia Corporation Dynamically adjustable implants and methods for reshaping tissue
US7278293B2 (en) * 2005-06-16 2007-10-09 Rosemount, Inc. Submersible probe
US20060283465A1 (en) 2005-06-16 2006-12-21 Nickel Janice H Smart drug delivery system and a method of implementation thereof
US8348930B2 (en) * 2005-07-01 2013-01-08 Microlin, Llc Fluid delivery device with a diffusion membrane and electrochemical pump
US20070074722A1 (en) 2005-09-21 2007-04-05 Kurve Technology, Inc. Medicament delivery control, monitoring, and reporting system and method
US20070078445A1 (en) 2005-09-30 2007-04-05 Curt Malloy Synchronization apparatus and method for iontophoresis device to deliver active agents to biological interfaces
US8936590B2 (en) 2005-11-09 2015-01-20 The Invention Science Fund I, Llc Acoustically controlled reaction device
US20070106277A1 (en) 2005-11-09 2007-05-10 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Remote controller for substance delivery system
US8992511B2 (en) 2005-11-09 2015-03-31 The Invention Science Fund I, Llc Acoustically controlled substance delivery device
US9067047B2 (en) 2005-11-09 2015-06-30 The Invention Science Fund I, Llc Injectable controlled release fluid delivery system
US8083710B2 (en) 2006-03-09 2011-12-27 The Invention Science Fund I, Llc Acoustically controlled substance delivery device
US20070106271A1 (en) 2005-11-09 2007-05-10 Searete Llc, A Limited Liability Corporation Remote control of substance delivery system
US9028467B2 (en) 2005-11-09 2015-05-12 The Invention Science Fund I, Llc Osmotic pump with remotely controlled osmotic pressure generation
US9254256B2 (en) 2005-11-09 2016-02-09 The Invention Science Fund I, Llc Remote controlled in vivo reaction method
US20070106170A1 (en) * 2005-11-10 2007-05-10 Conopco, Inc., D/B/A Unilever Apparatus and method for acquiring a signal
US8512241B2 (en) 2006-09-06 2013-08-20 Innurvation, Inc. Methods and systems for acoustic data transmission

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6464687B1 (en) * 1999-03-09 2002-10-15 Ball Semiconductor, Inc. Implantable drug delivery system
US20040121486A1 (en) * 2002-08-16 2004-06-24 Uhland Scott A. Controlled release device and method using electrothermal ablation
US20050123563A1 (en) * 2003-07-30 2005-06-09 Doranz Benjamin J. Lipoparticles comprising proteins, methods of making, and using the same

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