WO2007056066A3 - Bioabsorbable hemostatic gauze - Google Patents

Bioabsorbable hemostatic gauze Download PDF

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Publication number
WO2007056066A3
WO2007056066A3 PCT/US2006/042824 US2006042824W WO2007056066A3 WO 2007056066 A3 WO2007056066 A3 WO 2007056066A3 US 2006042824 W US2006042824 W US 2006042824W WO 2007056066 A3 WO2007056066 A3 WO 2007056066A3
Authority
WO
WIPO (PCT)
Prior art keywords
chitosan
water
bioabsorbable
hemostatic gauze
found
Prior art date
Application number
PCT/US2006/042824
Other languages
French (fr)
Other versions
WO2007056066A2 (en
Inventor
Vicky Feng
David H Hsu
Yan Yin
Original Assignee
Lifescience Plus Inc
Vicky Feng
David H Hsu
Yan Yin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lifescience Plus Inc, Vicky Feng, David H Hsu, Yan Yin filed Critical Lifescience Plus Inc
Priority to EP06827382A priority Critical patent/EP1951326A2/en
Priority to JP2008539031A priority patent/JP2009514597A/en
Publication of WO2007056066A2 publication Critical patent/WO2007056066A2/en
Publication of WO2007056066A3 publication Critical patent/WO2007056066A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/225Mixtures of macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/425Porous materials, e.g. foams or sponges
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/64Use of materials characterised by their function or physical properties specially adapted to be resorbable inside the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0052Mixtures of macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061Use of materials characterised by their function or physical properties
    • A61L26/0085Porous materials, e.g. foams or sponges
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061Use of materials characterised by their function or physical properties
    • A61L26/009Materials resorbable by the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/04Materials for stopping bleeding

Abstract

Bioabsorbable, water-soluble hemostatic cellulose based gauze matrix structures are described, including one or more species of chitosan, etherized cellulose, nonionic surfactant, water-soluble polysaccharide hydrocolloid and/or gum. Approximately 85% to 95% deacetylated decrystallized chitosan, present in an amount from about 2% to about 15% by weight, is found to be particularly advantageous. Favorable properties are found related to rapid stoppage of bleeding and bioabsorbability, among other, properties .
PCT/US2006/042824 2005-11-04 2006-11-02 Bioabsorbable hemostatic gauze WO2007056066A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP06827382A EP1951326A2 (en) 2005-11-04 2006-11-02 Bioabsorbable hemostatic gauze
JP2008539031A JP2009514597A (en) 2005-11-04 2006-11-02 Bioabsorbable hemostatic gauze

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US73332205P 2005-11-04 2005-11-04
US60/733,322 2005-11-04
US84631406P 2006-09-21 2006-09-21
US60/846,314 2006-09-21
US59115406P 2006-11-01 2006-11-01
US11/591,154 2006-11-01

Publications (2)

Publication Number Publication Date
WO2007056066A2 WO2007056066A2 (en) 2007-05-18
WO2007056066A3 true WO2007056066A3 (en) 2008-10-02

Family

ID=37948798

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/042824 WO2007056066A2 (en) 2005-11-04 2006-11-02 Bioabsorbable hemostatic gauze

Country Status (3)

Country Link
EP (1) EP1951326A2 (en)
JP (1) JP2009514597A (en)
WO (1) WO2007056066A2 (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8920514B2 (en) 2006-05-23 2014-12-30 Providence Health System—Oregon Systems and methods for introducing and applying a bandage structure within a body lumen or hollow body organ
US8951565B2 (en) 2003-12-23 2015-02-10 Hemcon Medical Technologies, Inc. Hemostatic compositions, assemblies, systems, and methods employing particulate hemostatic agents formed from hydrophilic polymer foam such as chitosan
US9004918B2 (en) 2001-06-14 2015-04-14 Hemcon Medical Technologies, Inc. Compositions, assemblies, and methods applied during or after a dental procedure to ameliorate fluid loss and/or promote healing, using a hydrophilic polymer sponge structure such as chitosan
US9204957B2 (en) 2005-03-17 2015-12-08 Hemcon Medical Technologies, Inc. Systems and methods for hemorrhage control and or tissue repair
US9205170B2 (en) 2008-05-02 2015-12-08 Hemcon Medical Technologies, Inc. Wound dressing devices and methods

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2463523B (en) * 2008-09-17 2013-05-01 Medtrade Products Ltd Wound care device
WO2010042540A1 (en) 2008-10-06 2010-04-15 Providence Health System - Oregon Foam medical devices and methods
CN105497966B (en) * 2015-12-28 2018-08-17 浙江科技学院 A kind of preparation facilities and its method of the hemostatic gauze product of the high absorbability of high stability
PL3187195T3 (en) 2015-12-31 2019-04-30 Upm Kymmene Corp A medical multi-layer product comprising nanofibrillar cellulose and a method for preparing thereof
KR102088475B1 (en) * 2019-10-15 2020-03-12 주식회사 엔도비전 Manufacturing Method of HR-Chitosan Dressing and HR-Chitosan Dressing Thereby
WO2022126628A1 (en) * 2020-12-18 2022-06-23 江苏奇力康皮肤药业有限公司 Liquid adhesive bandage and preparation method therefor
WO2022133629A1 (en) * 2020-12-21 2022-06-30 江苏奇力康皮肤药业有限公司 Spray type liquid bandage and preparation method therefor

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6177096B1 (en) * 1996-11-11 2001-01-23 Lts Lohmann Therapie-Systeme Gmbh Water soluble film for oral administration with instant wettability
EP1462122A1 (en) * 2003-03-25 2004-09-29 Ethicon, Inc. Hemostatic wound dressings and methods of making same
US20050123588A1 (en) * 2003-06-16 2005-06-09 Zhu Yong H. Deployable multifunctional hemostatic agent

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DE2449865B2 (en) 1974-10-17 1981-06-19 Schering Ag Berlin Und Bergkamen, 1000 Berlin Film-shaped medicinal product
DE3065372D1 (en) 1979-09-07 1983-11-24 Kingsdown Medical Consultants Wound dressing
US4543410A (en) 1982-06-21 1985-09-24 Morca, Inc. Absorbent cellulosic base structures
JPS6185315A (en) 1984-10-04 1986-04-30 Teikoku Seiyaku Kk Sheet-like preparation
EP0200508B1 (en) 1985-04-27 1991-10-02 Nitto Denko Corporation Adhesive oral bandages and oral pharmaceutical preparations
ES2019275B3 (en) 1985-10-09 1991-06-16 Desitin Arzneimittel Gmbh METHOD FOR THE PRODUCTION OF A METHOD OF ADMINISTRATION AND DOSAGE FOR REACTIVE DRUGS OR OTHER ACTIVE PRINCIPLES.
FR2592383B1 (en) 1985-12-26 1990-01-19 Adeline Andre PROCESS FOR THE PREPARATION OF A FLEXIBLE FILM OF CALCIUM ALGINATE
JPH0729915B2 (en) 1986-02-01 1995-04-05 帝國製薬株式会社 Sheet-shaped oral patch
US4929722A (en) 1986-06-06 1990-05-29 Union Carbide Chemicals And Plastics Company Inc. Acid decrystallization of aminopolysaccharides and derivatives thereof
DE3630603A1 (en) 1986-09-09 1988-03-10 Desitin Arzneimittel Gmbh PHARMACEUTICAL AND DOSAGE FORM FOR MEDICINAL ACTIVE SUBSTANCES, REAGENTS OR THE LIKE, AND METHOD FOR THE PRODUCTION THEREOF
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JP2656338B2 (en) 1989-01-31 1997-09-24 日東電工株式会社 Oral mucosa patch preparation
EP0452446B1 (en) 1989-10-14 1993-12-29 Desitin Arzneimittel GmbH Oral and dental hygiene preparation
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US4994277A (en) 1989-10-31 1991-02-19 Pfizer Hospital Products Group, Inc. Use of xanthan gum for preventing adhesions
WO1993006802A1 (en) 1991-10-09 1993-04-15 David Rolf Aqueous gel wound dressing and package
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Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6177096B1 (en) * 1996-11-11 2001-01-23 Lts Lohmann Therapie-Systeme Gmbh Water soluble film for oral administration with instant wettability
EP1462122A1 (en) * 2003-03-25 2004-09-29 Ethicon, Inc. Hemostatic wound dressings and methods of making same
US20050123588A1 (en) * 2003-06-16 2005-06-09 Zhu Yong H. Deployable multifunctional hemostatic agent

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9004918B2 (en) 2001-06-14 2015-04-14 Hemcon Medical Technologies, Inc. Compositions, assemblies, and methods applied during or after a dental procedure to ameliorate fluid loss and/or promote healing, using a hydrophilic polymer sponge structure such as chitosan
US9132206B2 (en) 2001-06-14 2015-09-15 Hemcon Medical Technologies, Inc. Hemostatic compositions, assemblies, systems, and methods employing particulate hemostatic agents formed from hydrophilic polymer foam such as chitosan
US8951565B2 (en) 2003-12-23 2015-02-10 Hemcon Medical Technologies, Inc. Hemostatic compositions, assemblies, systems, and methods employing particulate hemostatic agents formed from hydrophilic polymer foam such as chitosan
US9204957B2 (en) 2005-03-17 2015-12-08 Hemcon Medical Technologies, Inc. Systems and methods for hemorrhage control and or tissue repair
US8920514B2 (en) 2006-05-23 2014-12-30 Providence Health System—Oregon Systems and methods for introducing and applying a bandage structure within a body lumen or hollow body organ
US9205170B2 (en) 2008-05-02 2015-12-08 Hemcon Medical Technologies, Inc. Wound dressing devices and methods

Also Published As

Publication number Publication date
WO2007056066A2 (en) 2007-05-18
EP1951326A2 (en) 2008-08-06
JP2009514597A (en) 2009-04-09

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