WO2006135479A3 - Anti-scarring agents, therapeutic compositions, and use thereof - Google Patents

Anti-scarring agents, therapeutic compositions, and use thereof Download PDF

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Publication number
WO2006135479A3
WO2006135479A3 PCT/US2006/013030 US2006013030W WO2006135479A3 WO 2006135479 A3 WO2006135479 A3 WO 2006135479A3 US 2006013030 W US2006013030 W US 2006013030W WO 2006135479 A3 WO2006135479 A3 WO 2006135479A3
Authority
WO
WIPO (PCT)
Prior art keywords
implants
devices
treatment
therapeutic compositions
scarring agents
Prior art date
Application number
PCT/US2006/013030
Other languages
French (fr)
Other versions
WO2006135479A2 (en
Inventor
William L Hunter
Philip M Toleikis
David M Gravett
Arpita Maiti
Richard T Liggins
Aniko Takacs-Cox
Rui Avelar
Pierre E Signore
Troy A E Loss
Anne Hutchinson
Gaye Mcdonald-Jones
Fara Lakhani
Original Assignee
Angiotech Int Ag
William L Hunter
Philip M Toleikis
David M Gravett
Arpita Maiti
Richard T Liggins
Aniko Takacs-Cox
Rui Avelar
Pierre E Signore
Troy A E Loss
Anne Hutchinson
Gaye Mcdonald-Jones
Fara Lakhani
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angiotech Int Ag, William L Hunter, Philip M Toleikis, David M Gravett, Arpita Maiti, Richard T Liggins, Aniko Takacs-Cox, Rui Avelar, Pierre E Signore, Troy A E Loss, Anne Hutchinson, Gaye Mcdonald-Jones, Fara Lakhani filed Critical Angiotech Int Ag
Publication of WO2006135479A2 publication Critical patent/WO2006135479A2/en
Publication of WO2006135479A3 publication Critical patent/WO2006135479A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action

Abstract

The present invention provides devices or implants that comprise anti-scarring agents, methods or making such devices or implants, and methods of inhibiting fibrosis between the devices or implants and tissue surrounding the devices or implants. The present invention also provides compositions that comprise anti-fibrotic agents, and their uses in various medical applications including the prevention of surgical adhesions, treatment of inflammatory arthritis, treatment of scars and keloids, the treatment of vascular disease, and the prevention of cartilage loss.
PCT/US2006/013030 2005-05-10 2006-03-31 Anti-scarring agents, therapeutic compositions, and use thereof WO2006135479A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67929305P 2005-05-10 2005-05-10
US60/679,293 2005-05-10

Publications (2)

Publication Number Publication Date
WO2006135479A2 WO2006135479A2 (en) 2006-12-21
WO2006135479A3 true WO2006135479A3 (en) 2007-04-12

Family

ID=37532760

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/013030 WO2006135479A2 (en) 2005-05-10 2006-03-31 Anti-scarring agents, therapeutic compositions, and use thereof

Country Status (1)

Country Link
WO (1) WO2006135479A2 (en)

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US8845659B2 (en) 2010-02-25 2014-09-30 Covidien Lp Articulating endoscopic surgical clip applier
US8894665B2 (en) 2008-08-29 2014-11-25 Covidien Lp Endoscopic surgical clip applier
US8920438B2 (en) 2004-10-08 2014-12-30 Covidien Lp Apparatus for applying surgical clips
US8940742B2 (en) 2012-04-10 2015-01-27 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
US8961542B2 (en) 2010-07-28 2015-02-24 Covidien Lp Articulating clip applier cartridge
US8968337B2 (en) 2010-07-28 2015-03-03 Covidien Lp Articulating clip applier
US9011464B2 (en) 2010-11-02 2015-04-21 Covidien Lp Self-centering clip and jaw
US9113892B2 (en) 2013-01-08 2015-08-25 Covidien Lp Surgical clip applier
US9186153B2 (en) 2011-01-31 2015-11-17 Covidien Lp Locking cam driver and jaw assembly for clip applier
US9186136B2 (en) 2009-12-09 2015-11-17 Covidien Lp Surgical clip applier
US9359365B2 (en) 2013-10-04 2016-06-07 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
US9358015B2 (en) 2008-08-29 2016-06-07 Covidien Lp Endoscopic surgical clip applier with wedge plate
US9364239B2 (en) 2011-12-19 2016-06-14 Covidien Lp Jaw closure mechanism for a surgical clip applier
US9364216B2 (en) 2011-12-29 2016-06-14 Covidien Lp Surgical clip applier with integrated clip counter
US9364240B2 (en) 2004-10-08 2016-06-14 Covidien Lp Endoscopic surgical clip applier
US9408610B2 (en) 2012-05-04 2016-08-09 Covidien Lp Surgical clip applier with dissector
US9439654B2 (en) 2008-08-29 2016-09-13 Covidien Lp Endoscopic surgical clip applier
US9480477B2 (en) 2006-10-17 2016-11-01 Covidien Lp Apparatus for applying surgical clips
US9498227B2 (en) 2007-04-11 2016-11-22 Covidien Lp Surgical clip applier
US9526501B2 (en) 2009-12-15 2016-12-27 Covidien Lp Surgical clip applier
US9532787B2 (en) 2012-05-31 2017-01-03 Covidien Lp Endoscopic clip applier

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US9763668B2 (en) 2004-10-08 2017-09-19 Covidien Lp Endoscopic surgical clip applier
US7846361B2 (en) 2006-07-20 2010-12-07 Orbusneich Medical, Inc. Bioabsorbable polymeric composition for a medical device
EP2073754A4 (en) 2006-10-20 2012-09-26 Orbusneich Medical Inc Bioabsorbable polymeric composition and medical device background
US7959942B2 (en) 2006-10-20 2011-06-14 Orbusneich Medical, Inc. Bioabsorbable medical device with coating
CA2679523C (en) 2007-03-26 2015-06-23 Tyco Healthcare Group Lp Endoscopic surgical clip applier
WO2008132233A1 (en) * 2007-05-01 2008-11-06 Kuros Biosurgery Ag Composition, methods and kits for prevention of adhesion
US20110208212A1 (en) 2010-02-19 2011-08-25 Zergiebel Earl M Surgical clip applier
US8927004B1 (en) 2014-06-11 2015-01-06 Silver Bullet Therapeutics, Inc. Bioabsorbable substrates and systems that controllably release antimicrobial metal ions
US9821094B2 (en) 2014-06-11 2017-11-21 Silver Bullet Therapeutics, Inc. Coatings for the controllable release of antimicrobial metal ions
US8221396B2 (en) 2009-08-27 2012-07-17 Silver Bullet Therapeutics, Inc. Bone implants for the treatment of infection
US10265435B2 (en) 2009-08-27 2019-04-23 Silver Bullet Therapeutics, Inc. Bone implant and systems and coatings for the controllable release of antimicrobial metal ions
US9114197B1 (en) 2014-06-11 2015-08-25 Silver Bullett Therapeutics, Inc. Coatings for the controllable release of antimicrobial metal ions
EP2637608B1 (en) 2010-11-12 2016-03-02 Silver Bullet Therapeutics Inc. Bone implant and systems that controllably releases silver
US9775623B2 (en) 2011-04-29 2017-10-03 Covidien Lp Surgical clip applier including clip relief feature
US9968362B2 (en) 2013-01-08 2018-05-15 Covidien Lp Surgical clip applier
US9750500B2 (en) 2013-01-18 2017-09-05 Covidien Lp Surgical clip applier
WO2014190047A1 (en) 2013-05-21 2014-11-27 Northwestern University Para-xylene films and therapeutic uses thereof
US9775624B2 (en) 2013-08-27 2017-10-03 Covidien Lp Surgical clip applier
WO2015051241A1 (en) 2013-10-04 2015-04-09 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
CA2943075C (en) 2014-03-19 2023-02-28 Infinity Pharmaceuticals, Inc. Heterocyclic compounds for use in the treatment of pi3k-gamma mediated disorders
US9452242B2 (en) 2014-06-11 2016-09-27 Silver Bullet Therapeutics, Inc. Enhancement of antimicrobial silver, silver coatings, or silver platings
US9708348B2 (en) 2014-10-03 2017-07-18 Infinity Pharmaceuticals, Inc. Trisubstituted bicyclic heterocyclic compounds with kinase activities and uses thereof
US10702278B2 (en) 2014-12-02 2020-07-07 Covidien Lp Laparoscopic surgical ligation clip applier
US9931124B2 (en) 2015-01-07 2018-04-03 Covidien Lp Reposable clip applier
US10292712B2 (en) 2015-01-28 2019-05-21 Covidien Lp Surgical clip applier with integrated cutter
US10159491B2 (en) 2015-03-10 2018-12-25 Covidien Lp Endoscopic reposable surgical clip applier
MX2018003058A (en) 2015-09-14 2018-08-01 Infinity Pharmaceuticals Inc Solid forms of isoquinolinone derivatives, process of making, compositions comprising, and methods of using the same.
US10390831B2 (en) 2015-11-10 2019-08-27 Covidien Lp Endoscopic reposable surgical clip applier
WO2017161116A1 (en) 2016-03-17 2017-09-21 Infinity Pharmaceuticals, Inc. Isotopologues of isoquinolinone and quinazolinone compounds and uses thereof as pi3k kinase inhibitors
TWI794171B (en) 2016-05-11 2023-03-01 美商滬亞生物國際有限公司 Combination therapies of hdac inhibitors and pd-l1 inhibitors
TWI808055B (en) 2016-05-11 2023-07-11 美商滬亞生物國際有限公司 Combination therapies of hdac inhibitors and pd-1 inhibitors
SG11201810678WA (en) 2016-06-02 2018-12-28 Abbvie Inc Glucocorticoid receptor agonist and immunoconjugates thereof
US10919914B2 (en) 2016-06-08 2021-02-16 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
US10863992B2 (en) 2017-08-08 2020-12-15 Covidien Lp Endoscopic surgical clip applier
SG11202004867WA (en) 2017-12-01 2020-06-29 Abbvie Inc Glucocorticoid receptor agonist and immunoconjugates thereof
US20220176011A1 (en) * 2019-02-18 2022-06-09 Lankenau Institute For Medical Research Scar reducing wound closure materials
WO2021231563A1 (en) * 2020-05-13 2021-11-18 Spiral Therapeutics Inc. Gelling solutions for administration of compounds to the inner ear

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050175703A1 (en) * 2003-11-20 2005-08-11 Angiotech International Ag Polymer compositions and methods for their use

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050175703A1 (en) * 2003-11-20 2005-08-11 Angiotech International Ag Polymer compositions and methods for their use

Cited By (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8920438B2 (en) 2004-10-08 2014-12-30 Covidien Lp Apparatus for applying surgical clips
US9364240B2 (en) 2004-10-08 2016-06-14 Covidien Lp Endoscopic surgical clip applier
US9480477B2 (en) 2006-10-17 2016-11-01 Covidien Lp Apparatus for applying surgical clips
US9498227B2 (en) 2007-04-11 2016-11-22 Covidien Lp Surgical clip applier
US9358015B2 (en) 2008-08-29 2016-06-07 Covidien Lp Endoscopic surgical clip applier with wedge plate
US8894665B2 (en) 2008-08-29 2014-11-25 Covidien Lp Endoscopic surgical clip applier
US9439654B2 (en) 2008-08-29 2016-09-13 Covidien Lp Endoscopic surgical clip applier
US9113893B2 (en) 2008-08-29 2015-08-25 Covidien Lp Endoscopic surgical clip applier with clip retention
US9186136B2 (en) 2009-12-09 2015-11-17 Covidien Lp Surgical clip applier
US9526501B2 (en) 2009-12-15 2016-12-27 Covidien Lp Surgical clip applier
US8845659B2 (en) 2010-02-25 2014-09-30 Covidien Lp Articulating endoscopic surgical clip applier
US8968337B2 (en) 2010-07-28 2015-03-03 Covidien Lp Articulating clip applier
US8961542B2 (en) 2010-07-28 2015-02-24 Covidien Lp Articulating clip applier cartridge
US9011464B2 (en) 2010-11-02 2015-04-21 Covidien Lp Self-centering clip and jaw
US9186153B2 (en) 2011-01-31 2015-11-17 Covidien Lp Locking cam driver and jaw assembly for clip applier
US9364239B2 (en) 2011-12-19 2016-06-14 Covidien Lp Jaw closure mechanism for a surgical clip applier
US9364216B2 (en) 2011-12-29 2016-06-14 Covidien Lp Surgical clip applier with integrated clip counter
US9255108B2 (en) 2012-04-10 2016-02-09 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
US8940742B2 (en) 2012-04-10 2015-01-27 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
US9408610B2 (en) 2012-05-04 2016-08-09 Covidien Lp Surgical clip applier with dissector
US9532787B2 (en) 2012-05-31 2017-01-03 Covidien Lp Endoscopic clip applier
US9113892B2 (en) 2013-01-08 2015-08-25 Covidien Lp Surgical clip applier
US9359365B2 (en) 2013-10-04 2016-06-07 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof

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