WO2005001462A8 - System and method for determining an abused sensor during analyte measurement in a biological fluid - Google Patents

System and method for determining an abused sensor during analyte measurement in a biological fluid

Info

Publication number
WO2005001462A8
WO2005001462A8 PCT/US2004/019640 US2004019640W WO2005001462A8 WO 2005001462 A8 WO2005001462 A8 WO 2005001462A8 US 2004019640 W US2004019640 W US 2004019640W WO 2005001462 A8 WO2005001462 A8 WO 2005001462A8
Authority
WO
WIPO (PCT)
Prior art keywords
biological fluid
sensor
signal
determining
abused
Prior art date
Application number
PCT/US2004/019640
Other languages
French (fr)
Other versions
WO2005001462A1 (en
Inventor
David W Burke
Lance S Kuhn
James L Maxwell
Original Assignee
Roche Diagnostics Gmbh
Hoffmann La Roche
David W Burke
Lance S Kuhn
James L Maxwell
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics Gmbh, Hoffmann La Roche, David W Burke, Lance S Kuhn, James L Maxwell filed Critical Roche Diagnostics Gmbh
Priority to JP2006517447A priority Critical patent/JP2007524817A/en
Priority to CA2530300A priority patent/CA2530300C/en
Priority to EP04755678.2A priority patent/EP1639357B1/en
Publication of WO2005001462A1 publication Critical patent/WO2005001462A1/en
Publication of WO2005001462A8 publication Critical patent/WO2005001462A8/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3274—Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/02—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
    • G01N27/04—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance
    • G01N27/12—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance of a solid body in dependence upon absorption of a fluid; of a solid body in dependence upon reaction with a fluid, for detecting components in the fluid
    • G01N27/121—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance of a solid body in dependence upon absorption of a fluid; of a solid body in dependence upon reaction with a fluid, for detecting components in the fluid for determining moisture content, e.g. humidity, of the fluid
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/02—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y10T436/112499—Automated chemical analysis with sample on test slide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]
    • Y10T436/144444—Glucose

Abstract

A method for detecting an abused sensor for determining concentration of a medically significant component of a biological fluid placed upon the sensor comprising the steps of: a) placing the biological fluid sample upon the sensor; b) applying a first DC signal to the biological fluid; c) measuring a current response to the first DC signal; d) repeating step (c) at least once; e) calculating a normalized Cottrell Failsafe Ratio using the current response data; f) applying a second signal having an AC component to the biological fluid; g) measuring an AC response to the second signal; and h) combining the normalized Cottrell Failsafe Ratio and the AC response to produce an indication of whether the sensor has been abused.
PCT/US2004/019640 2003-06-20 2004-06-18 System and method for determining an abused sensor during analyte measurement in a biological fluid WO2005001462A1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2006517447A JP2007524817A (en) 2003-06-20 2004-06-18 System and method for determining a sensor misused during measurement of an analyte in a biological fluid
CA2530300A CA2530300C (en) 2003-06-20 2004-06-18 System and method for determining an abused sensor during analyte measurement in a biological fluid
EP04755678.2A EP1639357B1 (en) 2003-06-20 2004-06-18 Method for determining an abused sensor during analyte measurement in a blood sample

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US48029803P 2003-06-20 2003-06-20
US60/480,298 2003-06-20
US10/688,561 2003-10-17
US10/688,561 US7488601B2 (en) 2003-06-20 2003-10-17 System and method for determining an abused sensor during analyte measurement

Publications (2)

Publication Number Publication Date
WO2005001462A1 WO2005001462A1 (en) 2005-01-06
WO2005001462A8 true WO2005001462A8 (en) 2005-03-17

Family

ID=33519466

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/019640 WO2005001462A1 (en) 2003-06-20 2004-06-18 System and method for determining an abused sensor during analyte measurement in a biological fluid

Country Status (5)

Country Link
US (4) US7488601B2 (en)
EP (1) EP1639357B1 (en)
JP (3) JP2007524817A (en)
CA (1) CA2530300C (en)
WO (1) WO2005001462A1 (en)

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