WO2002007590A2 - Probe tip - Google Patents

Probe tip Download PDF

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Publication number
WO2002007590A2
WO2002007590A2 PCT/US2001/023192 US0123192W WO0207590A2 WO 2002007590 A2 WO2002007590 A2 WO 2002007590A2 US 0123192 W US0123192 W US 0123192W WO 0207590 A2 WO0207590 A2 WO 0207590A2
Authority
WO
WIPO (PCT)
Prior art keywords
inches
probe
ultrasound
scan
preferred
Prior art date
Application number
PCT/US2001/023192
Other languages
French (fr)
Other versions
WO2002007590A3 (en
Inventor
Rabindra Menezes
Original Assignee
Alcon Universal Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Universal Ltd. filed Critical Alcon Universal Ltd.
Priority to IL15385001A priority Critical patent/IL153850A0/en
Priority to CA002412577A priority patent/CA2412577A1/en
Priority to AU2001277972A priority patent/AU2001277972A1/en
Priority to JP2002513335A priority patent/JP2004504091A/en
Priority to EP01955922A priority patent/EP1303217A2/en
Priority to MXPA03000022A priority patent/MXPA03000022A/en
Priority to BR0112687-3A priority patent/BR0112687A/en
Publication of WO2002007590A2 publication Critical patent/WO2002007590A2/en
Publication of WO2002007590A3 publication Critical patent/WO2002007590A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/42—Details of probe positioning or probe attachment to the patient
    • A61B8/4272—Details of probe positioning or probe attachment to the patient involving the acoustic interface between the transducer and the tissue
    • A61B8/4281—Details of probe positioning or probe attachment to the patient involving the acoustic interface between the transducer and the tissue characterised by sound-transmitting media or devices for coupling the transducer to the tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/10—Eye inspection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G01N21/3581—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light using far infrared light; using Terahertz radiation

Definitions

  • This invention relates to ultrasonic devices and more particularly to ultrasound diagnostic probes tips used in ophthalmology.
  • A-Scan and B-Scan ultrasound diagnostic devices are used.
  • A-Scan biometry uses a relatively small probe and measures the distances between, and thicknesses of, various structures within the eye, such as lens thickness (L), anterior chamber depth (AC), posterior chamber depth (V) and overall axial length (AL). These measurements are useful in determining the required power of the artificial intraocular lens which is implanted during cataract surgery.
  • B-Scan ultrasound uses a larger probe having an internal motor that wobbles the ultrasound crystal contained within the handpiece.
  • B-Scan ultrasound creates a real time image of the eye and is used to detect the presence of retinal or choroidal detachments, artifacts in the vitreous, tumors or foreign bodies in the eye or to view the posterior segment of the eye when visualization is obscured.
  • B- Scan ultrasound will also make the same measurements made by A-Scan ultrasound.
  • Measurements using either A-Scan or B-Scan probes are usually performed using the contact method, during which the operative end of the probe is placed in contact with the cornea of the eye under anesthesia.
  • a special ultrasound fluid or gel is used to couple acoustically the probe with the lid or cornea of the eye. This acoustic coupling fluid can make it difficult to align the probe properly, and the gel may irritate the eye tissue.
  • the probe needs to be cleaned between uses, a difficult and time-consuming step. Even when the probe is cleaned adequately to minimize the spread of any pathogens, the fluid used to clean the probe can irritate eye tissue.
  • the contact method may not provide precise measurements due to corneal depression resulting from probe contact.
  • a second technique used to make A-Scan or B-Scan measurements is the immersion technique.
  • the immersion technique With the immersion technique, the eye is anesthetized and small cup is placed on the eye. The cup is then filled with an acoustic coupling fluid and the probe is inserted into the cup.
  • the immersion technique is considered to be 5 more accurate that the contact method because the probe does not contact and partially depress the eye.
  • the immersion technique is difficult to perform and time consuming and requires that the patient be laying down.
  • bubbles in the coupling fluid can cause inaccuracies in the measurements.
  • the present invention improves upon prior art methods by providing a soft, s partially solidified, water-based ultrasound conductive cap sided and shaped to fit over the operative end of an ultrasound probe.
  • the thickness of the cap may be varied to change the focal point during B-Scan biometry.
  • Still another objective of the present invention is to provide an ultrasound conductive cap that allows for more accurate ultrasound measurements.
  • Yet another objective of the present invention is to provide an ultrasound 5 conductive cap that helps prevent the spread of pathogens.
  • Yet another objective of the present invention is to allow for a biometry procedure that is simple and faster than the contact method and with the precision of the immersion method.
  • FIG. 1 is a top plan view of the probe cap of the present invention useful with an A-Scan ultrasound probe.
  • FIG. 2 is a cross-section view of the probe cap of the present invention taken along line 2-2 in FIG. 1.
  • FIG. 3 is a top plan view of the probe cap of the present invention useful with an B-Scan ultrasound probe.
  • FIG. 4 is a cross-section view of the probe cap of the present invention taken along line 4-4 in FIG. 3.
  • FIG. 5 a schematic representation of the cap illustrated in FIGS. 1 and 2 being used to take a measurement of an eye.
  • FIG. 6 a schematic representation of the cap illustrated in FIGS. 3 and 4 being used to take a measurement of an eye. '
  • probe tip 10 and 10' of the present invention are generally cup-shaped in cross-section, with wall 12 and 12' and end cap 14 and 14', end caps 14 or 14' closing off one end of wall 12 or 12', respectively.
  • Tip 10 illustrated in FIGS. 1 , 2 and 5 is suitable for use with an A-Scan probe and tip 10' illustrated in FIGS. 2, 3 and 6 is suitable for use with a B-Scan probe.
  • Tips 10 and 10' are preferably made of a water-based gel such as a cross-linked cellulose derivative, but any suitable material may be used. Suitable gels are commercially available for sources such as Pharmaceutical Innovations, Inc., Newark, New Jersey.
  • tip 10 suitable for use on an A-Scan probe may be of any suitable inner and outer diameter, but will generally have an inner radius R, of between 0.15 inches and 0.70 inches, with approximately 0.25 inches being preferred, and an outer radius R 0 of between 0.25 inches and 0.85 inches, with approximately 0.45 inches being preferred.
  • Wall 12 may be of any suitable height W h necessary to hold tip 10 on probe 16, but will generally be between 0.10 inches and 0.80 inches high, with approximately 0.40 inches being preferred.
  • vent hole 18 may be provided having a diameter D of between 0.01 inches and 0.10 inches, with 0.05 inches being preferred.
  • End cap 14 may have any suitable thickness EC t , but preferably is between 0.10 and 0.40 inches thick, with approximately 0.12 inches being preferred. End cap 14 also preferably is formed with a curved shape to fit probe 16 and eye 20 securely with minimal rocking and good acoustic contact, with an inner radius R 2 of between 0.75 inches and 1 .25 inches with approximately 0.90 inches being preferred and an outer radius R 3 of between 0.60 inches and 1.40 inches, with approximately 1 .00 inches being preferred. Wall 12 and end cap 14 are preferably joined by internal radius R 4 which is preferably between 0.01 inches and 0.05 inches, with 0.03 inches being preferred and external radius R 5 which is preferably between 0.05 inches and 0.1 5 inches, with 0.10 inches being preferred.
  • internal radius R 4 which is preferably between 0.01 inches and 0.05 inches, with 0.03 inches being preferred
  • external radius R 5 which is preferably between 0.05 inches and 0.1 5 inches, with 0.10 inches being preferred.
  • tip 10' suitable for use on an B-Scan probe may be of any suitable inner and outer diameter, but will generally have an inner radius R of between 0.50 inches and 1 .50 inches, with approximately 0.70 inches being s preferred, and an outer radius R 0 ' of between 0.85 inches and 1 .70 inches, with approximately 0.90 inches being preferred.
  • Wall 12' may be of any suitable height W h ' necessary to hold tip 10' on probe 22, but will generally be between 0.20 inches and 0.80 inches high, with approximately 0.25 inches being preferred.
  • vent hole 18' may be provided having a diameter D' 0 of between 0.01 inches and 0.10 inches, with 0.05 inches being preferred, located a distance W 1 from end cap 14' of between 0.01 inches and 0.10 inches, with 0.05 inches being preferred, from end cap 14'.
  • End cap 14' may have any suitable thickness EC t , but preferably is between 0.10 and 0.40 inches thick, with approximately 0.12 inches being preferred.
  • End cap 14 also preferably is formed with flat internal face 1 5 and 5 curved outer face 1 7 with and an outer radius R 3 ' of between 0.60 inches and 1.40 inches, with approximately 1 .00 inches being preferred.
  • Wall 12' and end cap 14' are preferably joined by internal radius R 4 ' which is preferably between 0.03 inches and 0.07 inches, with 0.05 inches being preferred and external radius R 5 ' which is preferably between 0.10 inches and 0.30 inches, with 0.20 inches being preferred. o
  • internal radius R 4 ' which is preferably between 0.03 inches and 0.07 inches, with 0.05 inches being preferred
  • external radius R 5 ' which is preferably between 0.10 inches and 0.30 inches, with 0.20 inches being preferred.
  • tip 10 or 10' may be place on the end of A- Scan probe 16 or B-Scan probe 22, respectively and used to make ultrasound measurements of eye 20 or 20'. Tips 10 and 10' may be shipped individually, or may be shipped in a multiple egg carton-like container (not shown).
  • probe tips of the present invention has been described with reference to ophthalmic ultrasound probes, the present invention may also be useful when used in combination with phased array cardiology probes, linear array, curved array and annual array radiology probes

Abstract

A soft, partially solidified, water-based ultrasound conductive cap sided and shaped to fit over the operative end of an ultrasound probe. The thickness of the cap may be varied to change the focal point during B-Scan biometry.

Description

PROBE TIP
This invention relates to ultrasonic devices and more particularly to ultrasound diagnostic probes tips used in ophthalmology.
Background of the Invention
Many devices use ultrasound energy to construct images of internal organs to help diagnose and treat diseases and other medical conditions. In ophthalmology, for example, both A-Scan and B-Scan ultrasound diagnostic devices are used.
As best seen in FIG. 5, A-Scan biometry uses a relatively small probe and measures the distances between, and thicknesses of, various structures within the eye, such as lens thickness (L), anterior chamber depth (AC), posterior chamber depth (V) and overall axial length (AL). These measurements are useful in determining the required power of the artificial intraocular lens which is implanted during cataract surgery.
As best seen in FIG. 6, B-Scan ultrasound uses a larger probe having an internal motor that wobbles the ultrasound crystal contained within the handpiece. B-Scan ultrasound creates a real time image of the eye and is used to detect the presence of retinal or choroidal detachments, artifacts in the vitreous, tumors or foreign bodies in the eye or to view the posterior segment of the eye when visualization is obscured. B- Scan ultrasound will also make the same measurements made by A-Scan ultrasound.
Measurements using either A-Scan or B-Scan probes are usually performed using the contact method, during which the operative end of the probe is placed in contact with the cornea of the eye under anesthesia. A special ultrasound fluid or gel is used to couple acoustically the probe with the lid or cornea of the eye. This acoustic coupling fluid can make it difficult to align the probe properly, and the gel may irritate the eye tissue. To prevent the spread of pathogens, the probe needs to be cleaned between uses, a difficult and time-consuming step. Even when the probe is cleaned adequately to minimize the spread of any pathogens, the fluid used to clean the probe can irritate eye tissue. In addition, the contact method may not provide precise measurements due to corneal depression resulting from probe contact. The contact method is preferred by most operators, however, because it is easy to perform compared to the immersion method. A second technique used to make A-Scan or B-Scan measurements is the immersion technique. With the immersion technique, the eye is anesthetized and small cup is placed on the eye. The cup is then filled with an acoustic coupling fluid and the probe is inserted into the cup. The immersion technique is considered to be 5 more accurate that the contact method because the probe does not contact and partially depress the eye. The immersion technique, however, is difficult to perform and time consuming and requires that the patient be laying down. In addition, bubbles in the coupling fluid can cause inaccuracies in the measurements.
Accordingly, a need continues to exist for a simple, safe, accurate and reliable o ultrasound coupling device.
Brief Summary of the Invention
The present invention improves upon prior art methods by providing a soft, s partially solidified, water-based ultrasound conductive cap sided and shaped to fit over the operative end of an ultrasound probe. The thickness of the cap may be varied to change the focal point during B-Scan biometry.
It is accordingly an objective of the present invention to provide an ultrasound conductive cap for ultrasound probes. o It is a further objective of the present invention to provide an ultrasound conductive cap that reduces or eliminates the need for an acoustic gel.
Still another objective of the present invention is to provide an ultrasound conductive cap that allows for more accurate ultrasound measurements.
Yet another objective of the present invention is to provide an ultrasound 5 conductive cap that helps prevent the spread of pathogens.
Yet another objective of the present invention is to allow for a biometry procedure that is simple and faster than the contact method and with the precision of the immersion method.
Other objectives, features and advantages of the present invention will become o apparent with reference to the drawings, and the following description of the drawings and claims. Brief Description of the Drawings
FIG. 1 is a top plan view of the probe cap of the present invention useful with an A-Scan ultrasound probe. FIG. 2 is a cross-section view of the probe cap of the present invention taken along line 2-2 in FIG. 1.
FIG. 3 is a top plan view of the probe cap of the present invention useful with an B-Scan ultrasound probe.
FIG. 4 is a cross-section view of the probe cap of the present invention taken along line 4-4 in FIG. 3.
FIG. 5 a schematic representation of the cap illustrated in FIGS. 1 and 2 being used to take a measurement of an eye.
FIG. 6 a schematic representation of the cap illustrated in FIGS. 3 and 4 being used to take a measurement of an eye. '
Detailed Description of the Invention
As best seen in FIGS. 2 and 4, probe tip 10 and 10' of the present invention are generally cup-shaped in cross-section, with wall 12 and 12' and end cap 14 and 14', end caps 14 or 14' closing off one end of wall 12 or 12', respectively. Tip 10 illustrated in FIGS. 1 , 2 and 5 is suitable for use with an A-Scan probe and tip 10' illustrated in FIGS. 2, 3 and 6 is suitable for use with a B-Scan probe. Tips 10 and 10' are preferably made of a water-based gel such as a cross-linked cellulose derivative, but any suitable material may be used. Suitable gels are commercially available for sources such as Pharmaceutical Innovations, Inc., Newark, New Jersey.
As best see in FIGS. 1 , 2 and 5 tip 10 suitable for use on an A-Scan probe may be of any suitable inner and outer diameter, but will generally have an inner radius R, of between 0.15 inches and 0.70 inches, with approximately 0.25 inches being preferred, and an outer radius R0 of between 0.25 inches and 0.85 inches, with approximately 0.45 inches being preferred. Wall 12 may be of any suitable height Wh necessary to hold tip 10 on probe 16, but will generally be between 0.10 inches and 0.80 inches high, with approximately 0.40 inches being preferred. To assist in the installation of tip 10 on probe 16, vent hole 18 may be provided having a diameter D of between 0.01 inches and 0.10 inches, with 0.05 inches being preferred. End cap 14 may have any suitable thickness ECt, but preferably is between 0.10 and 0.40 inches thick, with approximately 0.12 inches being preferred. End cap 14 also preferably is formed with a curved shape to fit probe 16 and eye 20 securely with minimal rocking and good acoustic contact, with an inner radius R2 of between 0.75 inches and 1 .25 inches with approximately 0.90 inches being preferred and an outer radius R3 of between 0.60 inches and 1.40 inches, with approximately 1 .00 inches being preferred. Wall 12 and end cap 14 are preferably joined by internal radius R4 which is preferably between 0.01 inches and 0.05 inches, with 0.03 inches being preferred and external radius R5 which is preferably between 0.05 inches and 0.1 5 inches, with 0.10 inches being preferred.
As best see in FIGS. 3, 4 and 6 tip 10' suitable for use on an B-Scan probe may be of any suitable inner and outer diameter, but will generally have an inner radius R of between 0.50 inches and 1 .50 inches, with approximately 0.70 inches being s preferred, and an outer radius R0' of between 0.85 inches and 1 .70 inches, with approximately 0.90 inches being preferred. Wall 12' may be of any suitable height Wh' necessary to hold tip 10' on probe 22, but will generally be between 0.20 inches and 0.80 inches high, with approximately 0.25 inches being preferred. To assist in the installation of tip 10' on probe 22, vent hole 18' may be provided having a diameter D' 0 of between 0.01 inches and 0.10 inches, with 0.05 inches being preferred, located a distance W1 from end cap 14' of between 0.01 inches and 0.10 inches, with 0.05 inches being preferred, from end cap 14'. End cap 14' may have any suitable thickness ECt, but preferably is between 0.10 and 0.40 inches thick, with approximately 0.12 inches being preferred. End cap 14 also preferably is formed with flat internal face 1 5 and 5 curved outer face 1 7 with and an outer radius R3' of between 0.60 inches and 1.40 inches, with approximately 1 .00 inches being preferred. Wall 12' and end cap 14' are preferably joined by internal radius R4' which is preferably between 0.03 inches and 0.07 inches, with 0.05 inches being preferred and external radius R5' which is preferably between 0.10 inches and 0.30 inches, with 0.20 inches being preferred. o One skilled in the art will recognize that the dimensions discussed above may be increased or decreased as required for the probe selected.
In use, as best seen in FIGS. 5 and 6, tip 10 or 10' may be place on the end of A- Scan probe 16 or B-Scan probe 22, respectively and used to make ultrasound measurements of eye 20 or 20'. Tips 10 and 10' may be shipped individually, or may be shipped in a multiple egg carton-like container (not shown).
While the probe tips of the present invention has been described with reference to ophthalmic ultrasound probes, the present invention may also be useful when used in combination with phased array cardiology probes, linear array, curved array and annual array radiology probes
While certain embodiments of the present invention have been described above, these descriptions are given for purposes of illustration and explanation. Variations, changes, modifications and departures from the systems and methods disclosed above may be adopted without departure from the scope or spirit of the present invention.

Claims

I claim: 1 . A probe tip, comprising: a) a circumferential wall; and b) an end cap closing off an end of the wall,
wherein the wall and the end cap are sized and shaped to fit on an end of a probe and the tip is made from a water-based, ultrasonically conductive material.
2. The probe tip of claim 1 wherein the water-based ultrasonically conductive material is a cross-linked cellulose derivative.
3. The probe tip of claim 1 wherein the end cap is sized and shaped to fit on the end of the probe with minimal rocking and good acoustic contact.
4. The probe tip of claim 1 wherein the wall contains a vent hole.
5. The probe tip of claim 2 wherein the gel is a cross-linked cellulose derivative.
PCT/US2001/023192 2000-07-25 2001-07-23 Probe tip WO2002007590A2 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
IL15385001A IL153850A0 (en) 2000-07-25 2001-07-23 Probe tip
CA002412577A CA2412577A1 (en) 2000-07-25 2001-07-23 Probe tip
AU2001277972A AU2001277972A1 (en) 2000-07-25 2001-07-23 Probe tip
JP2002513335A JP2004504091A (en) 2000-07-25 2001-07-23 Probe tip
EP01955922A EP1303217A2 (en) 2000-07-25 2001-07-23 Probe tip
MXPA03000022A MXPA03000022A (en) 2000-07-25 2001-07-23 Probe tip.
BR0112687-3A BR0112687A (en) 2000-07-25 2001-07-23 Probe tip

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62533900A 2000-07-25 2000-07-25
US09/625,339 2000-07-25

Publications (2)

Publication Number Publication Date
WO2002007590A2 true WO2002007590A2 (en) 2002-01-31
WO2002007590A3 WO2002007590A3 (en) 2002-05-23

Family

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PCT/US2001/023192 WO2002007590A2 (en) 2000-07-25 2001-07-23 Probe tip

Country Status (8)

Country Link
EP (1) EP1303217A2 (en)
JP (1) JP2004504091A (en)
AU (1) AU2001277972A1 (en)
BR (1) BR0112687A (en)
CA (1) CA2412577A1 (en)
IL (1) IL153850A0 (en)
MX (1) MXPA03000022A (en)
WO (1) WO2002007590A2 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2410693B (en) * 2002-10-25 2007-08-01 Robert Harvey Rines Method of ameliorating vision-inhibiting effects of cataracts and the like
EP1905360A1 (en) * 2006-09-29 2008-04-02 Nidek Co., Ltd. Ophthalmic ultrasonic diagnostic apparatus
WO2014127253A1 (en) * 2013-02-15 2014-08-21 Naimco, Inc. Preconfigured ultrasound conductive medium
US9050053B2 (en) 2013-02-15 2015-06-09 Naimco, Inc. Ultrasound device with cavity for conductive medium

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3133434A1 (en) * 1981-08-24 1983-03-10 Gilbert 07041 Millburn N.J. Buchalter Contact medium and method for attaching a transducer to a patient
EP0344773A2 (en) * 1988-06-02 1989-12-06 Takiron Co., Ltd. Liquid segment polyurethane gel and couplers for ultrasonic diagnostic probe comprising the same
WO1990001902A1 (en) * 1988-08-30 1990-03-08 Fujitsu Limited Acoustic coupler
EP0628284A1 (en) * 1992-12-02 1994-12-14 Shiseido Company Limited Contact medium for probe of ultrasonic diagnostic apparatus
EP1038551A1 (en) * 1999-03-25 2000-09-27 Technomed Medical Systems Coupling agent for therapeutic ultrasound

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61146234A (en) * 1984-12-20 1986-07-03 ダイセル化学工業株式会社 Catalytic substance for ultrasonic diagnosis

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3133434A1 (en) * 1981-08-24 1983-03-10 Gilbert 07041 Millburn N.J. Buchalter Contact medium and method for attaching a transducer to a patient
EP0344773A2 (en) * 1988-06-02 1989-12-06 Takiron Co., Ltd. Liquid segment polyurethane gel and couplers for ultrasonic diagnostic probe comprising the same
WO1990001902A1 (en) * 1988-08-30 1990-03-08 Fujitsu Limited Acoustic coupler
EP0628284A1 (en) * 1992-12-02 1994-12-14 Shiseido Company Limited Contact medium for probe of ultrasonic diagnostic apparatus
EP1038551A1 (en) * 1999-03-25 2000-09-27 Technomed Medical Systems Coupling agent for therapeutic ultrasound

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Section Ch, Week 198633 Derwent Publications Ltd., London, GB; Class A96, AN 1986-215135 XP002187012 & JP 61 146234 A (DAICEL CHEM IND LTD), 3 July 1986 (1986-07-03) *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2410693B (en) * 2002-10-25 2007-08-01 Robert Harvey Rines Method of ameliorating vision-inhibiting effects of cataracts and the like
EP1905360A1 (en) * 2006-09-29 2008-04-02 Nidek Co., Ltd. Ophthalmic ultrasonic diagnostic apparatus
US7455406B2 (en) 2006-09-29 2008-11-25 Nidek Co., Ltd. Ophthalmic ultrasonic diagnostic apparatus
WO2014127253A1 (en) * 2013-02-15 2014-08-21 Naimco, Inc. Preconfigured ultrasound conductive medium
US9050053B2 (en) 2013-02-15 2015-06-09 Naimco, Inc. Ultrasound device with cavity for conductive medium

Also Published As

Publication number Publication date
WO2002007590A3 (en) 2002-05-23
MXPA03000022A (en) 2004-09-13
AU2001277972A1 (en) 2002-02-05
CA2412577A1 (en) 2002-01-31
BR0112687A (en) 2003-07-29
JP2004504091A (en) 2004-02-12
EP1303217A2 (en) 2003-04-23
IL153850A0 (en) 2003-07-31

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