WO2001013115A3 - Method and device for identifying a biopolymer sequence on a solid surface - Google Patents

Method and device for identifying a biopolymer sequence on a solid surface Download PDF

Info

Publication number
WO2001013115A3
WO2001013115A3 PCT/DE2000/002758 DE0002758W WO0113115A3 WO 2001013115 A3 WO2001013115 A3 WO 2001013115A3 DE 0002758 W DE0002758 W DE 0002758W WO 0113115 A3 WO0113115 A3 WO 0113115A3
Authority
WO
WIPO (PCT)
Prior art keywords
biopolymer
identifying
der
oder
spread
Prior art date
Application number
PCT/DE2000/002758
Other languages
German (de)
French (fr)
Other versions
WO2001013115A2 (en
Inventor
Wolf Bertling
Joerg Hassmann
Hans Kosak
Original Assignee
Wolf Bertling
Joerg Hassmann
Hans Kosak
November Ag Molekulare Medizin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wolf Bertling, Joerg Hassmann, Hans Kosak, November Ag Molekulare Medizin filed Critical Wolf Bertling
Priority to EP00962216A priority Critical patent/EP1203237A2/en
Priority to CA002386518A priority patent/CA2386518A1/en
Priority to AU74030/00A priority patent/AU7403000A/en
Publication of WO2001013115A2 publication Critical patent/WO2001013115A2/en
Publication of WO2001013115A3 publication Critical patent/WO2001013115A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6825—Nucleic acid detection involving sensors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching

Abstract

The invention relates to a method for identifying a biopolymer spread on a first surface of a solid substrate, whereby the first biopolymer is brought into contact with a second biopolymer which spread on a second surface, whereby said second biopolymer has an affinity for the first biopolymer; Biopolymer in Kontakt gebracht wird und wobei die Identifikation des ersten Biopolymers vorgenommen wird durch Auswertung der durch affinitätsbedingte Adhäsion ausgelösten Anderung der Impedanz, der Leitfähigkeit im Gleichstrom- und/oder Wechselstrombereich in Abhängigkeit von einer aufgeprägten Wechselspannungs- oder Wechselstromfrequenz.
PCT/DE2000/002758 1999-08-16 2000-08-12 Method and device for identifying a biopolymer sequence on a solid surface WO2001013115A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP00962216A EP1203237A2 (en) 1999-08-16 2000-08-12 Method and device for identifying a biopolymer sequence on a solid surface
CA002386518A CA2386518A1 (en) 1999-08-16 2000-08-12 Method and device for identifying a biopolymer sequence on a solid surface
AU74030/00A AU7403000A (en) 1999-08-16 2000-08-12 Method and device for identifying a biopolymer sequence on solid surface

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19938138A DE19938138C2 (en) 1999-08-16 1999-08-16 Method and device for identifying a biopolymer sequence on solid surfaces
DE19938138.0 1999-08-16

Publications (2)

Publication Number Publication Date
WO2001013115A2 WO2001013115A2 (en) 2001-02-22
WO2001013115A3 true WO2001013115A3 (en) 2001-08-23

Family

ID=7918107

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE2000/002758 WO2001013115A2 (en) 1999-08-16 2000-08-12 Method and device for identifying a biopolymer sequence on a solid surface

Country Status (5)

Country Link
EP (1) EP1203237A2 (en)
AU (1) AU7403000A (en)
CA (1) CA2386518A1 (en)
DE (1) DE19938138C2 (en)
WO (1) WO2001013115A2 (en)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7645421B2 (en) 2003-06-20 2010-01-12 Roche Diagnostics Operations, Inc. System and method for coding information on a biosensor test strip
US7645373B2 (en) 2003-06-20 2010-01-12 Roche Diagnostic Operations, Inc. System and method for coding information on a biosensor test strip
US7718439B2 (en) 2003-06-20 2010-05-18 Roche Diagnostics Operations, Inc. System and method for coding information on a biosensor test strip
US8058077B2 (en) 2003-06-20 2011-11-15 Roche Diagnostics Operations, Inc. Method for coding information on a biosensor test strip
US8206565B2 (en) 2003-06-20 2012-06-26 Roche Diagnostics Operation, Inc. System and method for coding information on a biosensor test strip
US8298828B2 (en) 2003-06-20 2012-10-30 Roche Diagnostics Operations, Inc. System and method for determining the concentration of an analyte in a sample fluid
US9410915B2 (en) 2004-06-18 2016-08-09 Roche Operations Ltd. System and method for quality assurance of a biosensor test strip

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10113711A1 (en) * 2001-03-16 2002-09-26 Lifebits Ag Identifying bio-chemical reactions e.g., DNA hybridization, comprises digitally scanning specific detector molecules in an array of accurately-defined and discrete points with a sample, for statistical evaluation
DE10113550A1 (en) * 2001-03-20 2002-10-02 Infineon Technologies Ag Method for detecting macromolecular biopolymers using an electrode arrangement

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0244326A2 (en) * 1986-04-30 1987-11-04 BIO MERIEUX Société anonyme dite: Method for detecting and/or identifying a biological substance in a liquid medium with the aid of electrical measurements, and apparatus for carrying out this method
US5567301A (en) * 1995-03-01 1996-10-22 Illinois Institute Of Technology Antibody covalently bound film immunobiosensor
WO1998019153A1 (en) * 1996-10-26 1998-05-07 The Victoria University Of Manchester Sensor employing impedance measurements
WO1998031839A2 (en) * 1997-01-21 1998-07-23 President And Fellows Of Harvard College Electronic-property probing of biological molecules at surfaces
WO2000077523A1 (en) * 1999-06-10 2000-12-21 Motorola, Inc. Biosensors which utilize charge neutral conjugated polymers

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5605798A (en) * 1993-01-07 1997-02-25 Sequenom, Inc. DNA diagnostic based on mass spectrometry
US5591578A (en) * 1993-12-10 1997-01-07 California Institute Of Technology Nucleic acid mediated electron transfer
US5866336A (en) * 1996-07-16 1999-02-02 Oncor, Inc. Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon
WO1998048275A1 (en) * 1997-04-22 1998-10-29 Thomas Schalkhammer Reinforced cluster optical sensors
EP1009852A2 (en) * 1997-09-04 2000-06-21 Bayer Corporation Oligonucleotide probes bearing quenchable fluorescent labels, and methods of use thereof
JP2001526381A (en) * 1997-12-05 2001-12-18 マックス−プランク−ゲゼルシャフト・ツア・フェルデルング・デア・ヴィッセンシャフテン・エー・ファオ Nucleic acid identification method by matrix-assisted laser desorption / ionization mass spectrometry

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0244326A2 (en) * 1986-04-30 1987-11-04 BIO MERIEUX Société anonyme dite: Method for detecting and/or identifying a biological substance in a liquid medium with the aid of electrical measurements, and apparatus for carrying out this method
US5567301A (en) * 1995-03-01 1996-10-22 Illinois Institute Of Technology Antibody covalently bound film immunobiosensor
WO1998019153A1 (en) * 1996-10-26 1998-05-07 The Victoria University Of Manchester Sensor employing impedance measurements
WO1998031839A2 (en) * 1997-01-21 1998-07-23 President And Fellows Of Harvard College Electronic-property probing of biological molecules at surfaces
WO2000077523A1 (en) * 1999-06-10 2000-12-21 Motorola, Inc. Biosensors which utilize charge neutral conjugated polymers

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
H-W FINK, C SCHÖNENBERGER: "Electrical conduction through DNA molecules", NATURE, vol. 398, 1 April 1999 (1999-04-01), pages 407 - 410, XP002162319 *
S O KELLEY, N M JACKSON, M G HILL, J K BARTON: "Long-Range Electron Transfer through DNA films", ANGEW. CHEM. INT. ED., vol. 38, no. 7, 1999, pages 941 - 945, XP002162320 *
SOUTEYRAND E ET AL: "Comparison between electrochemical and optoelectrochemical impedance measurements for detection of DNA hybridization.", APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, vol. 89, no. 2-3, November 2000 (2000-11-01), pages 195 - 207, XP000989714, ISSN: 0273-2289 *

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7645421B2 (en) 2003-06-20 2010-01-12 Roche Diagnostics Operations, Inc. System and method for coding information on a biosensor test strip
US7645373B2 (en) 2003-06-20 2010-01-12 Roche Diagnostic Operations, Inc. System and method for coding information on a biosensor test strip
US7718439B2 (en) 2003-06-20 2010-05-18 Roche Diagnostics Operations, Inc. System and method for coding information on a biosensor test strip
US8058077B2 (en) 2003-06-20 2011-11-15 Roche Diagnostics Operations, Inc. Method for coding information on a biosensor test strip
US8206565B2 (en) 2003-06-20 2012-06-26 Roche Diagnostics Operation, Inc. System and method for coding information on a biosensor test strip
US8298828B2 (en) 2003-06-20 2012-10-30 Roche Diagnostics Operations, Inc. System and method for determining the concentration of an analyte in a sample fluid
US8507289B1 (en) 2003-06-20 2013-08-13 Roche Diagnostics Operations, Inc. System and method for coding information on a biosensor test strip
US9410915B2 (en) 2004-06-18 2016-08-09 Roche Operations Ltd. System and method for quality assurance of a biosensor test strip

Also Published As

Publication number Publication date
WO2001013115A2 (en) 2001-02-22
AU7403000A (en) 2001-03-13
DE19938138C2 (en) 2003-02-13
DE19938138A1 (en) 2001-03-01
CA2386518A1 (en) 2001-02-22
EP1203237A2 (en) 2002-05-08

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