WO2000047197A3 - Alkylating agents for treatment of cellular proliferation - Google Patents

Alkylating agents for treatment of cellular proliferation Download PDF

Info

Publication number
WO2000047197A3
WO2000047197A3 PCT/US2000/003667 US0003667W WO0047197A3 WO 2000047197 A3 WO2000047197 A3 WO 2000047197A3 US 0003667 W US0003667 W US 0003667W WO 0047197 A3 WO0047197 A3 WO 0047197A3
Authority
WO
WIPO (PCT)
Prior art keywords
cellular proliferation
treatment
alkylating agents
alkylating agent
restenosis
Prior art date
Application number
PCT/US2000/003667
Other languages
French (fr)
Other versions
WO2000047197A2 (en
Inventor
Angelica Alvarado
Robert Eury
Irina D Pomerantseva
Michael Froix
Original Assignee
Quanam Medical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quanam Medical Corp filed Critical Quanam Medical Corp
Priority to JP2000598150A priority Critical patent/JP2002536406A/en
Priority to CA002362883A priority patent/CA2362883A1/en
Priority to EP00914574A priority patent/EP1150670A2/en
Priority to AU35947/00A priority patent/AU3594700A/en
Publication of WO2000047197A2 publication Critical patent/WO2000047197A2/en
Publication of WO2000047197A3 publication Critical patent/WO2000047197A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

A method of inhibiting cellular proliferation associated with a hyperproliferative condition, such as restenosis, is described. The method includes administering an alkylating agent. A stent for local administration of the alkylating agent is also described.
PCT/US2000/003667 1999-02-12 2000-02-10 Alkylating agents for treatment of cellular proliferation WO2000047197A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2000598150A JP2002536406A (en) 1999-02-12 2000-02-10 Alkylating agents for the treatment of cell proliferation
CA002362883A CA2362883A1 (en) 1999-02-12 2000-02-10 Alkylating agents for treatment of cellular proliferation
EP00914574A EP1150670A2 (en) 1999-02-12 2000-02-10 Alkylating agents for treatment of cellular proliferation
AU35947/00A AU3594700A (en) 1999-02-12 2000-02-10 Alkylating agents for treatment of cellular proliferation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11995199P 1999-02-12 1999-02-12
US60/119,951 1999-02-12

Publications (2)

Publication Number Publication Date
WO2000047197A2 WO2000047197A2 (en) 2000-08-17
WO2000047197A3 true WO2000047197A3 (en) 2001-04-05

Family

ID=22387376

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/003667 WO2000047197A2 (en) 1999-02-12 2000-02-10 Alkylating agents for treatment of cellular proliferation

Country Status (5)

Country Link
EP (1) EP1150670A2 (en)
JP (1) JP2002536406A (en)
AU (1) AU3594700A (en)
CA (1) CA2362883A1 (en)
WO (1) WO2000047197A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002056872A2 (en) * 2000-10-31 2002-07-25 Chemgenex Therapeutics, Inc. Antiproliferative colchicine compositions and uses thereof
DE10115740A1 (en) 2001-03-26 2002-10-02 Ulrich Speck Preparation for restenosis prophylaxis
US7018371B2 (en) 2001-05-07 2006-03-28 Xoft, Inc. Combination ionizing radiation and radiosensitizer delivery devices and methods for inhibiting hyperplasia
US6537195B2 (en) 2001-05-07 2003-03-25 Xoft, Microtube, Inc. Combination x-ray radiation and drug delivery devices and methods for inhibiting hyperplasia
DE10244847A1 (en) 2002-09-20 2004-04-01 Ulrich Prof. Dr. Speck Medical device for drug delivery

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991012846A1 (en) * 1990-02-26 1991-09-05 Slepian Marvin J Method and apparatus for treatment of tubular organs
WO1998008566A1 (en) * 1996-08-30 1998-03-05 Duke University Manipulations of nitrosative and oxidatives stress in the treatment of disease
WO1998052944A1 (en) * 1997-05-19 1998-11-26 Sugen, Inc. Heteroarylcarboxamide compounds active against protein tyrosine kinase related disorders
WO1998057671A2 (en) * 1997-06-18 1998-12-23 Boston Scientific Corporation Polycarbonate-polyurethane dispersions for thrombo-resistant coatings
WO1999001118A2 (en) * 1997-07-01 1999-01-14 Atherogenics, Inc. Antioxidant enhancement of therapy for hyperproliferative conditions
EP0970711A2 (en) * 1998-06-30 2000-01-12 Ethicon, Inc. Process for coating stents

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991012846A1 (en) * 1990-02-26 1991-09-05 Slepian Marvin J Method and apparatus for treatment of tubular organs
WO1998008566A1 (en) * 1996-08-30 1998-03-05 Duke University Manipulations of nitrosative and oxidatives stress in the treatment of disease
WO1998052944A1 (en) * 1997-05-19 1998-11-26 Sugen, Inc. Heteroarylcarboxamide compounds active against protein tyrosine kinase related disorders
WO1998057671A2 (en) * 1997-06-18 1998-12-23 Boston Scientific Corporation Polycarbonate-polyurethane dispersions for thrombo-resistant coatings
WO1999001118A2 (en) * 1997-07-01 1999-01-14 Atherogenics, Inc. Antioxidant enhancement of therapy for hyperproliferative conditions
EP0970711A2 (en) * 1998-06-30 2000-01-12 Ethicon, Inc. Process for coating stents

Also Published As

Publication number Publication date
CA2362883A1 (en) 2000-08-17
JP2002536406A (en) 2002-10-29
WO2000047197A2 (en) 2000-08-17
AU3594700A (en) 2000-08-29
EP1150670A2 (en) 2001-11-07

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