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Publication numberWO1997020580 A1
Publication typeApplication
Application numberPCT/GB1996/003000
Publication dateJun 12, 1997
Filing dateDec 6, 1996
Priority dateDec 6, 1995
Also published asCA2239203A1, EP0865298A1
Publication numberPCT/1996/3000, PCT/GB/1996/003000, PCT/GB/1996/03000, PCT/GB/96/003000, PCT/GB/96/03000, PCT/GB1996/003000, PCT/GB1996/03000, PCT/GB1996003000, PCT/GB199603000, PCT/GB96/003000, PCT/GB96/03000, PCT/GB96003000, PCT/GB9603000, WO 1997/020580 A1, WO 1997020580 A1, WO 1997020580A1, WO 9720580 A1, WO 9720580A1, WO-A1-1997020580, WO-A1-9720580, WO1997/020580A1, WO1997020580 A1, WO1997020580A1, WO9720580 A1, WO9720580A1
InventorsTariq Khan
ApplicantAepact Limited
Export CitationBiBTeX, EndNote, RefMan
External Links: Patentscope, Espacenet
Drug therapy
WO 1997020580 A1
Description  available in English
Patent Citations
Cited PatentFiling datePublication dateApplicantTitle
WO1988007378A1 *Mar 9, 1988Oct 6, 1988Cancer Research Campaign Technology Ltd.Improvements relating to drug delivery systems
WO1993013805A1 *Jan 11, 1993Jul 22, 1993Kenneth Dawson BagshaweCytotoxic drug therapy
Non-Patent Citations
Reference
1 *BAGSHAWE K D: "ANTIBODY-DIRECTED ENZYME PRODRUG THERAPY (ADEPT)", JOURNAL OF CONTROLLED RELEASE, vol. 28, no. 1/03, 1 January 1994 (1994-01-01), pages 187 - 193, XP000435249
2 *DOWELL, ROBERT I. ET AL: "New Mustard Prodrugs for Antibody-Directed Enzyme Prodrug Therapy: Alternatives to the Amide Link", J. MED. CHEM. (1996), 39(5), 1100-5 CODEN: JMCMAR;ISSN: 0022-2623, 1996, XP002027294
3 *SPRINGER, CAROLINE J. ET AL: "Optimization of Alkylating Agent Prodrugs Derived from Phenol and Aniline Mustards: A New Clinical Candidate Prodrug (ZD2767) for Antibody-Directed Enzyme Prodrug Therapy", J. MED. CHEM. (1995), 38(26), 5051-65 CODEN: JMCMAR;ISSN: 0022-2623, 1995, XP002027293
4 *SVENSSON H P ET AL: "MONOCLONAL ANTIBODY-B-LACTAMASE CONJUGATES FOR THE ACTIVATION OF A CEPHALOSPORIN MUSTARD PRODRUG", BIOCONJUGATE CHEMISTRY, vol. 3, no. 2, 1 March 1992 (1992-03-01), pages 176 - 181, XP000262174
Referenced by
Citing PatentFiling datePublication dateApplicantTitle
WO2000024426A1 *Oct 22, 1999May 4, 2000Intelligene Ltd.Ribozymes used as prodrugs
WO2011036457A1 *Sep 23, 2010Mar 31, 2011Mologic LtdPeptide clearing agents
WO2014181085A1Apr 30, 2014Nov 13, 2014Kenneth Dawson BagshaweTumour therapy
CN102665768A *Sep 23, 2010Sep 12, 2012莫洛迪克有限公司肽清除剂
CN102665768B *Sep 23, 2010Jan 21, 2015莫洛迪克有限公司肽清除剂
US6867231Jun 15, 1998Mar 15, 2005Enzacta R & D LimitedTherapeutic systems
US7138122Mar 13, 2002Nov 21, 2006Enzacta R & D LimitedTherapeutic systems
US8846861Sep 23, 2010Sep 30, 2014Mologic LtdPeptide clearing agents
Classifications
International ClassificationA61K31/505, C07D239/38, A61K39/395, A61K47/48, C07D213/72, A61P43/00, A61P35/00, A61K38/43, A61K45/00, A61K31/00, C07C333/04
Cooperative ClassificationB82Y5/00, A61K47/6899, C07C333/04, C07D239/38, C07D213/72
European ClassificationB82Y5/00, A61K47/48T8P, C07D239/38, C07C333/04, C07D213/72
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