WO1993005732A1 - Intraocular lens - Google Patents

Intraocular lens Download PDF

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Publication number
WO1993005732A1
WO1993005732A1 PCT/DE1992/000768 DE9200768W WO9305732A1 WO 1993005732 A1 WO1993005732 A1 WO 1993005732A1 DE 9200768 W DE9200768 W DE 9200768W WO 9305732 A1 WO9305732 A1 WO 9305732A1
Authority
WO
WIPO (PCT)
Prior art keywords
lens
intraocular lens
intraocular
eye
refractive index
Prior art date
Application number
PCT/DE1992/000768
Other languages
German (de)
French (fr)
Inventor
Karlheinz Schmidt
Original Assignee
Karlheinz Schmidt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Karlheinz Schmidt filed Critical Karlheinz Schmidt
Publication of WO1993005732A1 publication Critical patent/WO1993005732A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1602—Corrective lenses for use in addition to the natural lenses of the eyes or for pseudo-phakic eyes
    • A61F2/1605—Anterior chamber lenses for use in addition to the natural lenses of the eyes, e.g. iris fixated, iris floating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1602—Corrective lenses for use in addition to the natural lenses of the eyes or for pseudo-phakic eyes

Definitions

  • Intraocular lens Intraocular lens
  • the ametropia requires a diverging lens, this is designed as a plano-concave or biconcave intraocular lens.
  • the lens also has a feel, i.e. Supporting or fastening elements with which the position of the lens is fixed in the anterior chamber.
  • haptics e.g. curved spring legs used to support the intraocular lens in the chamber angle or clamping elements to clamp the intraocular lens in the periphery of the iris.
  • the state of the art is W091 / 07147, in which a plano-concave intraocular lens is described, which is implanted in the anterior chamber of the eye and serves as a diffusing lens. The natural eye lens is not removed.
  • plano-concave or biconcave anterior chamber lenses are much thicker at their edges than in the middle and therefore run counter to the natural geometry within the eye.
  • the thick edge of the intraocular lens is therefore very close to the front inner wall of the eye, so that there can be touches that permanently cloud the cornea.
  • the invention is based on the object of specifying an implantable intraocular lens which, in the implanted state, acts as a diverging lens, but which, in contrast to normal diverging lenses, is thinner at the edge than at the center.
  • a lens material with a refractive index which is smaller than that of the aqueous humor is thus used.
  • a lens of this type is therefore relatively thin at the edges and relatively thick in the middle, thus conforming to the natural shape of the eye in the anterior chamber area on. There is therefore no contact with the inner wall of the eye, so that clouding of the cornea is also avoided.
  • fluorine-containing, transparent polymers in question e.g. Fluoropolymers which have a refractive index up to 1.295.
  • fluorescent materials e.g. polytetrafluoroethylene (PTFE).
  • FIG. 1 shows a partial cross section through an eye into which an intraocular lens according to the invention is inserted in addition to the existing natural eye lens;
  • FIG. 2 shows several cross sections of intraocular lenses according to the invention; 3 to 5 representations of an intraocular lens according to a further embodiment of the invention.
  • FIG. 1 shows a schematic partial cross section through a human eye with cornea 1, iris 2 and natural eye lens 3.
  • the cavity of the eye is filled with water 4.
  • a plan-convex intraocular lens is inserted into the anterior chamber, the material of the lens having a refractive index less than 1.336.
  • the material is e.g. PTFE with a refractive index of 1.295.
  • Fig. 2 several intraocular lenses made of a material with a refractive index n of 1.295 on a scale of 10: 1 are given, the refractive power or the diopter D -8, -6, -5 or -10. All lenses are thinner at the edges than in the middle.
  • an intraocular lens 5 * is shown, the lens part 6 is concave / convex.
  • the lens part 6 is integrated in a haptic 7, which is designed as a flat wing on both sides of the intraocular lens. 5, this intraocular lens 5 can be inserted between the natural eye lens 3 and the iris 2.
  • the haptic 7 has a curvature corresponding to the normal curvature of the eye lens 3.

Abstract

To achieve negative refraction, it is proposed to make the intraocular lens (5) of a material with a lower refractive index than that of the aqueous humour. Alternatively, a hollow intraocular lens (5') may be used. The outer edges of the intraocular lenses are thinner than the centres so that they espouse the natural shape of the eye well on being implanted, especially when the intraocular lens is implanted in addition to the actual natural lens (3).

Description

IntraokularlinseIntraocular lens
Es ist bekannt, bei der Trübung der natürlichen Augenlinse diese zu entfernen und durch eine implantierte Intraokular¬ linse zu ersetzen.It is known to remove the cloudy eye lens and replace it with an implanted intraocular lens.
Es ist auch bekannt, starke Fehlsichtigkeit durch Implantation einer zusätzlichen Intraokularlinse in die vordere Augen¬ kammer zu korrigieren, wobei die natürliche Augenlinse erhalten bleibt. Für diese zusätzliche Korrektur sind, abhängig von der Art der Fehlsichtigkeit des Patienten, Sammellinsen mit positivem Dioptrienwert bzw. Zerstreuungs¬ linsen mit negativem Dioptrienwert notwendig.It is also known to correct severe ametropia by implanting an additional intraocular lens in the anterior chamber of the eye, the natural eye lens being retained. For this additional correction, depending on the type of ametropia of the patient, converging lenses with a positive diopter value or diverging lenses with a negative diopter value are necessary.
Erfordert die Fehlsichtigkeit eine Zerstreuungslinse, so wird diese als plankonkave oder bikonkave Intraokularlinse ausgebildet. Die Linse hat zusätzlich eine Haptik, d.h. Stütz- oder Befestigungselemente, mit der die Lage der Linse in der Vorderkammer fixiert ist. Als Haptik werden z.B. gebogene FederSchenkel verwendet, die die Intraokularlinse im Kammerwinkel abstützen oder Klemmelemente, um die Intraoku¬ larlinse in die Peripherie der Iris zu klemmen.If the ametropia requires a diverging lens, this is designed as a plano-concave or biconcave intraocular lens. The lens also has a feel, i.e. Supporting or fastening elements with which the position of the lens is fixed in the anterior chamber. As haptics e.g. curved spring legs used to support the intraocular lens in the chamber angle or clamping elements to clamp the intraocular lens in the periphery of the iris.
Als Stand der Technik sei die W091/07147 genannt, in der eine plankonkave Intraokularlinse beschrieben ist, die in die Vorderkammer des Auges implantiert ist und als Zer¬ streuungslinse dient. Die natürliche Augenlinse wird hierbei nicht entfernt.The state of the art is W091 / 07147, in which a plano-concave intraocular lens is described, which is implanted in the anterior chamber of the eye and serves as a diffusing lens. The natural eye lens is not removed.
Der schwere Nachteil dieser plankonkaven oder bikonkaven Vorderkammerlinsen liegt darin, daß diese Zerstreuungs¬ linsen an ihrem Rand wesentlich dicker sind als in der Mitte und daher der natürlichen Geometrie innerhalb des Auges zuwiderlaufen. Der dicke Rand der Intraokularlinse liegt daher sehr nahe an der vorderen Innenwand des Auges, so daß es dort zu Berührungen kommen kann, die auf Dauer eine Trübung der Hornhaut nach sich ziehen.The serious disadvantage of these plano-concave or biconcave anterior chamber lenses is that these diverging lenses are much thicker at their edges than in the middle and therefore run counter to the natural geometry within the eye. The thick edge of the intraocular lens is therefore very close to the front inner wall of the eye, so that there can be touches that permanently cloud the cornea.
Es ist weiterhin aus den US-Patentschriften 47 69 035 und 48 71 363 bekannt, Intraokularlinsen entweder in der Hinter¬ kammer oder in der Vorderkammer des Auges zu implantieren, ohne daß dabei die natürliche Augenlinse entfernt wird. Die dort beschriebenen Intraokularlinsen sind, sofern sie als Sammellinsen ausgebildet sind, wie üblich am Rand dünner als in der Mitte; es sind jedoch auch Zerstreuungslinsen angegeben, die, ebenfalls üblich, aufgrund ihrer etwa bi¬ konkaven Konfiguration a Rande dicker sind als in der Mitte.It is also known from US Pat. Nos. 47 69 035 and 48 71 363 to implant intraocular lenses either in the back chamber or in the front chamber of the eye without removing the natural eye lens. The intraocular lenses described there, as long as they are designed as converging lenses, are, as usual, thinner at the edge than in the middle; However, diverging lenses are also specified which, likewise common, are a margin thicker on the edge than in the middle due to their approximately bi-concave configuration.
Der Erfindung liegt die Aufgabe zugrunde, eine implantier¬ bare Intraokularlinse anzugeben, die im implantierten Zu¬ stand zwar als Zerstreuungslinse wirkt, die aber im Gegen¬ satz zu normalen Zerstreuungslinsen am Rand dünner ist als in der Mitte.The invention is based on the object of specifying an implantable intraocular lens which, in the implanted state, acts as a diverging lens, but which, in contrast to normal diverging lenses, is thinner at the edge than at the center.
Diese Aufgabe ist gemäß der Erfindung durch das im kenn¬ zeichnenden Teil des Patentanspruches 1 angegebenen Merk¬ mal gelöst.This object is achieved according to the invention by the feature specified in the characterizing part of patent claim 1.
Gemäß der Erfindung wird somit ein Linsenmaterial mit einem Brechungsindex verwendet, der kleiner als derjenige des Kammerwassers ist. Damit kann man eine bikonvexe, plan¬ konvexe oder konkav/konvexe Intraokularlinse herstellen, die gleichwohl als Zerstreuungslinse, d.h. als Minuslinse, wirkt. Eine derartige Linse ist demnach an den Rändern relativ dünn und in der Mitte relativ dick, paßt sich demnach der natürlichen Gestalt des Auges im Vorderkammerbereich an. Zu Berührungen der Innenwand des Auges kommt es daher nicht, so daß auch Trübungen der Hornhaut vermieden werden.According to the invention, a lens material with a refractive index which is smaller than that of the aqueous humor is thus used. This allows a biconvex, plan-convex or concave / convex intraocular lens to be produced, which nevertheless acts as a diverging lens, ie as a minus lens. A lens of this type is therefore relatively thin at the edges and relatively thick in the middle, thus conforming to the natural shape of the eye in the anterior chamber area on. There is therefore no contact with the inner wall of the eye, so that clouding of the cornea is also avoided.
Als Material für derartige Intraokularlinsen kommen z.B. fluorhaltige, transparente Polymere in Frage, z.B. Fluor¬ polymere, die einen Brechungsindex bis zu 1,295 aufweisen. Beispiele für derartige Materialien sind Polytetrafluor- ethylen (PTFE) .As material for such intraocular lenses e.g. fluorine-containing, transparent polymers in question, e.g. Fluoropolymers which have a refractive index up to 1.295. Examples of such materials are polytetrafluoroethylene (PTFE).
Geht man z.B. von dem angegebenen Brechungsindex von 1,295 für ein Fluorpolymer aus, dann beträgt bei einer plankonvexe Intraokularlinse von -10 Dioptrien der Radius der Konvexi¬ tät 4,1 mm, entsprechend der Differenz des Brechungsindex 1,336 des Kammerwassers und 1,295 des Fluorpolymers. Diese Linse ist somit in der Mitte sehr viel dicker als außen und paßt sich so den anatomischen Verhältnissen im Auge an.If you go e.g. from the specified refractive index of 1.295 for a fluoropolymer, then with a plano-convex intraocular lens of -10 diopters the radius of the convexity is 4.1 mm, corresponding to the difference between the refractive index 1.336 of the aqueous humor and 1.295 of the fluoropolymer. This lens is therefore much thicker in the middle than outside and adapts to the anatomical conditions in the eye.
Es sind zwar für Intraokularlinsen Materialien bekannt, die fluorhaltige Polymere enthalten; vgl. z.B. die US- PS 4 955 900. Die Brechungsindices dieser bekannten Mate¬ rialien liegen jedoch deutlich über dem Brechungsindex für das Kammerwasser, nämlich bei Werten oberhalb 1,6.Materials are known for intraocular lenses that contain fluorine-containing polymers; see. e.g. US Pat. No. 4,955,900. However, the refractive indices of these known materials are well above the refractive index for the aqueous humor, namely at values above 1.6.
Die Erfindung ist in Ausführungsbeispielen anhand der Zeich¬ nung näher erläutert. In dieser stellen dar:The invention is explained in more detail in exemplary embodiments with reference to the drawing. In this represent:
Fig. 1 ein Teilquerschnitt durch ein Auge, in das zusätz¬ lich zur vorhandenen natürlichen Augenlinse eine Intraokularlinse gemäß der Erfindung eingesetzt ist;1 shows a partial cross section through an eye into which an intraocular lens according to the invention is inserted in addition to the existing natural eye lens;
Fig. 2 mehrere Querschnitte von Intraokularlinsen gemäß der Erfindung; Fig. 3 bis 5 Darstellungen einer Intraokularlinse gemäß einem weiteren Ausführungsbeispiel der Erfindung.2 shows several cross sections of intraocular lenses according to the invention; 3 to 5 representations of an intraocular lens according to a further embodiment of the invention.
In Fig. 1 ist ein schematischer Teilquerschnitt durch ein menschliches Auge mit Hornhaut 1, Iris 2 und natürlicher Augenlinse 3 gezeigt. Der Hohlraum des Auges ist mit Kammer¬ wasser 4 ausgefüllt. In die Vorderkammer ist eine plan¬ konvexe Intraokularlinse eingesetzt, wobei das Material der Linse einen Brechungsindex kleiner als 1,336 aufweist. Das Material ist z.B. PTFE mit einem Brechungsindex von 1,295.1 shows a schematic partial cross section through a human eye with cornea 1, iris 2 and natural eye lens 3. The cavity of the eye is filled with water 4. A plan-convex intraocular lens is inserted into the anterior chamber, the material of the lens having a refractive index less than 1.336. The material is e.g. PTFE with a refractive index of 1.295.
In Fig. 2 sind mehrere Intraokularlinsen aus einem Material mit einem BrechungsIndex n von 1,295 in einem Maßstab von 10:1 angegeben, wobei die Brechkraft bzw. die Dioptrie D -8, -6, -5 bzw. -10 ist. Sämtliche Linsen sind an den Rändern dünner als in der Mitte.In Fig. 2 several intraocular lenses made of a material with a refractive index n of 1.295 on a scale of 10: 1 are given, the refractive power or the diopter D -8, -6, -5 or -10. All lenses are thinner at the edges than in the middle.
In den Fig. 3 bis 5 ist eine Intraokularlinse 5* dargestellt, deren Linsenteil 6 konkav/konvex ist. Der Linsenteil 6 ist in eine Haptik 7 integriert, die zu beiden Seiten der Intraokularlinse als flächiger Flügel ausgebildet ist. Diese Intraokularlinse 5 kann entsprechend Fig. 5 zwischen natürlicher Augenlinse 3 und Iris 2 eingesetzt sein. Die Haptik 7 weist eine Krümmung entsprechend der normalen Krümmung der Augenlinse 3 auf.3 to 5, an intraocular lens 5 * is shown, the lens part 6 is concave / convex. The lens part 6 is integrated in a haptic 7, which is designed as a flat wing on both sides of the intraocular lens. 5, this intraocular lens 5 can be inserted between the natural eye lens 3 and the iris 2. The haptic 7 has a curvature corresponding to the normal curvature of the eye lens 3.
Als Material für die Intraokularlinsen können neben dem erwähnten PTFE z.B. Polychlortrifluoroethlyen, Ethylen- Clortrifluorethylen-Copolymere, Hexafluorpropylen, amorphe Fluorpolymere sowie Mischungen solcher Stoffe mit anderen Stoffen verwendet werden. As material for the intraocular lenses, in addition to the PTFE mentioned, e.g. Polychlorotrifluoroethylene, ethylene-chlorotrifluoroethylene copolymers, hexafluoropropylene, amorphous fluoropolymers and mixtures of such substances with other substances can be used.

Claims

Patentansprüche Claims
1. Intraokularlinse, insbesondere zusätzliche, zu der natür¬ lichen Augenlinse in die Vorder- bzw. Hinterkammer des Auges implantierbare Intraokularlinse, dadurch gekenn¬ zeichnet, daß für die Intraokularlinse ein Material mit einem Brechungsindex kleiner als der Brechungsindex des Kammerwassers verwendet wird.1. Intraocular lens, in particular additional intraocular lens that can be implanted to the natural eye lens in the anterior or posterior chamber of the eye, characterized in that a material with a refractive index less than the refractive index of the aqueous humor is used for the intraocular lens.
2. Intraokularlinse nach Anspruch 1, dadurch gekennzeich¬ net, daß das Material ein fluorhaltiges Polymer oder ein Material mit einem Zuschlag von Fluorpolymeren ist.2. intraocular lens according to claim 1, characterized gekennzeich¬ net that the material is a fluorine-containing polymer or a material with an addition of fluoropolymers.
3. Intraokularlinse nach einem der vorhergehenden Ansprüche, dadurch gekennzeichnet, daß die Intraokularlinse (5, 5', 5") zur Erzielung einer negativen Brechkraft einen bikonvexen, plankonvexen oder konkav/konvexen Linsenteil aufweist. 3. Intraocular lens according to one of the preceding claims, characterized in that the intraocular lens (5, 5 ', 5 ") has a biconvex, plano-convex or concave / convex lens part to achieve a negative refractive power.
PCT/DE1992/000768 1991-09-19 1992-09-10 Intraocular lens WO1993005732A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19914131229 DE4131229C1 (en) 1991-09-19 1991-09-19
DEP4131229.5 1991-09-19

Publications (1)

Publication Number Publication Date
WO1993005732A1 true WO1993005732A1 (en) 1993-04-01

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6127497A (en) * 1996-06-17 2000-10-03 Exxon Chemical Patents Inc. Elevated pressure polymerization processes with late transition metal catalyst systems
US6613343B2 (en) 2000-04-12 2003-09-02 Pharmacia Groningen Bv Injectable intraocular accommodating lens
US7048759B2 (en) 2000-02-24 2006-05-23 Advanced Medical Optics, Inc. Intraocular lenses

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0861056A2 (en) * 1994-04-19 1998-09-02 Staar Surgical, AG Artificial lens insertible between the iris and the natural lens of the eye

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US4615702A (en) * 1984-09-10 1986-10-07 Koziol Jeffrey E Intraocular lens and method of forming the lens
EP0212616A2 (en) * 1985-08-21 1987-03-04 Kingston Technologies, Inc. Intraocular lens
US4685922A (en) * 1986-06-25 1987-08-11 Peyman Gholam A Alterable refractive power intraocular lenses
US4769035A (en) * 1987-06-02 1988-09-06 Kelman Charles D Artificial lens and the method for implanting such lens
US4892543A (en) * 1989-02-02 1990-01-09 Turley Dana F Intraocular lens providing accomodation
EP0422644A2 (en) * 1989-10-11 1991-04-17 Daikin Industries, Ltd. Fluorine-containing block copolymer and artificial lens comprising the same
FR2666735A1 (en) * 1990-09-13 1992-03-20 Klw Intraocular implant with internal cavity

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DE2525377A1 (en) * 1975-06-06 1976-12-16 Inprohold Ets Dioptric lens prosthesis for human eye - having two discs hermetically sealed together and to side fastening lugs
DE3428895C2 (en) * 1984-08-04 1986-07-10 Dr. K. Schmidt-Apparatebau, 5205 St Augustin Artificial intraocular lens
JP2672974B2 (en) * 1988-06-10 1997-11-05 株式会社メニコン Intraocular lens
US4871363A (en) * 1988-07-21 1989-10-03 Kelman Charles D Corrective intraocular lens
US4955902A (en) * 1989-11-13 1990-09-11 Kelman Charles D Decentered intraocular lens

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4615702A (en) * 1984-09-10 1986-10-07 Koziol Jeffrey E Intraocular lens and method of forming the lens
EP0212616A2 (en) * 1985-08-21 1987-03-04 Kingston Technologies, Inc. Intraocular lens
US4685922A (en) * 1986-06-25 1987-08-11 Peyman Gholam A Alterable refractive power intraocular lenses
US4769035A (en) * 1987-06-02 1988-09-06 Kelman Charles D Artificial lens and the method for implanting such lens
US4892543A (en) * 1989-02-02 1990-01-09 Turley Dana F Intraocular lens providing accomodation
EP0422644A2 (en) * 1989-10-11 1991-04-17 Daikin Industries, Ltd. Fluorine-containing block copolymer and artificial lens comprising the same
FR2666735A1 (en) * 1990-09-13 1992-03-20 Klw Intraocular implant with internal cavity

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6127497A (en) * 1996-06-17 2000-10-03 Exxon Chemical Patents Inc. Elevated pressure polymerization processes with late transition metal catalyst systems
US7048759B2 (en) 2000-02-24 2006-05-23 Advanced Medical Optics, Inc. Intraocular lenses
US6613343B2 (en) 2000-04-12 2003-09-02 Pharmacia Groningen Bv Injectable intraocular accommodating lens

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