WO1992012747A1 - Device for dispensing controlled dose units, particularly of the disposable type - Google Patents

Device for dispensing controlled dose units, particularly of the disposable type Download PDF

Info

Publication number
WO1992012747A1
WO1992012747A1 PCT/FR1992/000037 FR9200037W WO9212747A1 WO 1992012747 A1 WO1992012747 A1 WO 1992012747A1 FR 9200037 W FR9200037 W FR 9200037W WO 9212747 A1 WO9212747 A1 WO 9212747A1
Authority
WO
WIPO (PCT)
Prior art keywords
fins
return
pusher
sleeve
push rod
Prior art date
Application number
PCT/FR1992/000037
Other languages
French (fr)
Inventor
André Taddei
Original Assignee
Micro Dose Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Micro Dose Pharma filed Critical Micro Dose Pharma
Publication of WO1992012747A1 publication Critical patent/WO1992012747A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159Dose expelling manners
    • A61M5/31591Single dose, i.e. individually set dose administered only once from the same medicament reservoir, e.g. including single stroke limiting means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31578Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
    • A61M5/3158Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by axially moving actuator operated by user, e.g. an injection button
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2403Ampoule inserted into the ampoule holder
    • A61M2005/2407Ampoule inserted into the ampoule holder from the rear
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2485Ampoule holder connected to rest of syringe
    • A61M2005/2488Ampoule holder connected to rest of syringe via rotation, e.g. threads or bayonet
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/50Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
    • A61M5/5013Means for blocking the piston or the fluid passageway to prevent illegal refilling of a syringe
    • A61M5/502Means for blocking the piston or the fluid passageway to prevent illegal refilling of a syringe for blocking the piston
    • A61M2005/5033Means for blocking the piston or the fluid passageway to prevent illegal refilling of a syringe for blocking the piston by use of an intermediate blocking member positioned between the syringe barrel and the piston rod to prevent retraction of the latter, e.g. toothed clip placed on the piston rod
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31545Setting modes for dosing
    • A61M5/31548Mechanically operated dose setting member
    • A61M5/3155Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • A61M5/31551Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/50Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
    • A61M5/5013Means for blocking the piston or the fluid passageway to prevent illegal refilling of a syringe

Definitions

  • the invention relates to the delivery of controlled doses of a fluid product, that is to say liquid or pasty.
  • an elongated hollow body capable of internally housing a refill of a liquid or pasty product, actuated by pushing, 0 as well as receiving on the downstream side of the refill a delivery nozzle,
  • the known devices are for the most part very complex in structure. Their constitution is therefore hardly compatible with the concept of disposable syringe, which is essential for various reasons: to avoid contamination in the medical field, or more simply approval of use, if it is for example the distribution of glue.
  • the definition of the dose be precise, and preferably verifiable by several means, including for example acoustic means for the blind.
  • the main object of the present invention is to provide suitable solutions to the difficulties noted above.
  • the push rod is of cylindrical or prismatic shape (in principle smooth) and the non-return means comprises at least one semi-rigid fin inclined on the axis, and cooperating with bracing with the lateral surface of said push rod.
  • semi-rigid fin means a fin which is inherently flexible due to the bracing. It turned out that this non-return means already considerably simpli ies the construction of the device.
  • the or the fins form non-return upstream for the push rod relative to the body.
  • this push rod cooperates with a plurality of regularly distributed fins, converging towards the center in the direction of the end piece of the device, with a geometry corresponding to that of the cross section of the rod.
  • the fins provide, at the same time as the non-return function, that of holding the rod inside the body.
  • the pusher cooperates with the push rod also by means of at least one other semi-fin. rigid, preferably a plurality of fins, inclined on the axis, and cooperating with bracing with the lateral surface of the push rod, so as to also form non-return, but this time downstream, for the pusher relative to the rod.
  • this or these other fins are regularly distributed, converge towards the center in the direction of the end piece of the device, with a geometry corresponding to that of the cross section of the rod.
  • these fins at the same time as the non-return function, contribute to the maintenance of the rod inside the body.
  • This second set of fins is in principle mounted on the same support. It can also be made deformable, by pivoting around an annular guideline, so as to favor the return upstream of the second fins relative to the rod. We can thus order the implementation of a new dosage. Insofar as the pusher returns upstream with these second fins, the current dose is memorized, if desired.
  • braking means forming a non-return upstream of the second fins relative to the body.
  • an elastic compression force is exerted between these second fins and the body.
  • FIG. 1 is a longitudinal sectional view of a device according to the invention.
  • FIG. 2 is an enlarged partial view corresponding to the right part of Figure 1, where appears most of the means according to the invention;
  • - Figure 3 is a simplified diagram to facilitate the understanding of the mechanisms visible in Figures 1 and 2;
  • FIGS. 4 and 4A are two partial perspective views detailing the structure of the non-return means with metal fins, in two respective embodiments;
  • FIGS. 5A to 5C illustrate a particular embodiment of the push rod
  • FIGS. 6A to 6D illustrate a particular embodiment of the sleeve
  • FIGS. 7A to 7C illustrate a particular embodiment of the body of the device, in its right part
  • FIG. 8 illustrates a first embodiment of the ring with its lever
  • FIGS. 9A to 9D illustrate a particular embodiment of the ring with its lever forming a braking device and notched action
  • FIG. 11A and 11B illustrate another alternative embodiment of the fins 55, in two parts.
  • the syringe comprises in the left part a housing 1 containing a cartridge or cartridge 3 containing for example insulin.
  • This cartridge is provided, at one end, with an actuating piston 34, and at the other with a head 32 housing a seal passable by a needle.
  • a needle holder (not shown) can be fixed at 12 to the housing 1.
  • the means 12 can be a thread or other fixing means.
  • the housing 1 is fixed by gluing, crimping or any other means on the rest 2 of the body (which will be called hereinafter "the body").
  • This body 2 (FIGS. 1, 2 and 7A to 7C) comprises, on the left, a cylindrical part 21, followed by a central part provided with a longitudinal notch 22 (we see in FIG. 7C the lever 70). After that, the body 2 offers an internal radial shoulder 23. On the other side of the shoulder, that is to say on the right, it defines at 24 a housing, which can be provided with longitudinal grooves 24A (FIG. 7B).
  • the pusher essentially consists of three main parts: a push rod 40, a sleeve 50 and a ring 60.
  • the push rod will be considered below as being external to the pusher assembly, although it naturally contributes to the push function.
  • This push rod 40 ( Figures SA to 5C) has a polygonal cross section, for example square with cut corners ( Figure 5C). At one end, an enlarged end piece 42 is made in one piece with the rod 40. At the other end is provided an added end piece 41.
  • the sleeve (FIGS. 6A to 6D) is designated as a whole by 50.
  • An external central shoulder 53 separates it into two parts 51 and 54, of generally cylindrical shape. His right part 51 is provided with an external thread 52, and with a reinforced end 58, adapted to rotate relative to the rod 40.
  • cap 59 serving simply to facilitate the rotational drive thereof.
  • the ring 60 (FIG. 8) is in the form of an elongated cylinder, of circular cross section. But there is provided at the top a recess 63, on which comes, as an integral part and projecting longitudinally, a lever 70. Internally, the ring is provided with a thread 64 adapted to cooperate with the thread 52 of the sleeve. The lever 70 projects in overhang in the axis above the ring.
  • FIGS. 9A to 9D A variant of the ring is illustrated in FIGS. 9A to 9D.
  • the body 61 of the ring has a flat portion 62 at the top.
  • the lever 70 has a special shape. On the side of its end (towards the left in the figures), it is split into two parts 71 and 72, which define notches 75 and 76.
  • Corresponding notches 27 and 28 are provided on the notch 22 of the body. While the notching of the body at 27 and 28 (FIG. 9D) is symmetrical, it is noted that the notches 75 and 76 of the lever are offset by half a step.
  • a rift making it possible to act with a finger, such as the thumb, on the lever 70 for purposes which will be described later.
  • a set of fins 55 which also bears on the rod.
  • This set of fins essentially has the function of controlling the advance of the rod by pushing the ring.
  • the fins 55 are here made of a piece of material on a metal ring, advantageously provided towards the rear with an axial tongue 56.
  • the periphery of the ring and / or the tongue 56 can be embedded in the synthetic material of the ring 50.
  • the ring 50 is for example overmolded on these metal parts.
  • the periphery of the ring and / or the tongue 56 can be embedded in the synthetic material of the lever 70, for example by overmolding.
  • the tongue 56 can form a brake, by its corners which engage on the internal wall of the body 2.
  • Other embodiments of the brake are conceivable.
  • FIG. 3 it can be seen in a simplified manner that at rest the shoulder 53 of the sleeve comes to bear on the downstream stop 23 of the body. This is the zero dose, in the embodiment described.
  • Unscrewing the sleeve relative to the ring makes it possible to fix a dose.
  • precise indications can be given on the side of the control button 59, with for example display of visual indications at the level of the window visible at 59A in FIG. 1.
  • the shoulder 53 has therefore deviated by a certain distance from the shoulder 23.
  • the limit excursion is defined by the left shoulder of the part 29.
  • the spring 69 is weak, in which case its return is not enough to return the sleeve 50 - ring 60 assembly to its starting position; by the lever 70, acting on the tongue 56 associated with the fins 55 (FIG. 4), the user makes the fins 55 rotate annually, which facilitates the upstream return, which the user helps with the lever 70.
  • the spring 69 is strong, and its return is sufficient to return the sleeve 50 - ring 60 assembly to its starting position; in this case, the tongue 56 associated with the fins 55 (FIG. 4A) is provided with a widening (to the right of the figure, ie upstream) which causes it to come into engagement by its points on the body, forming a non-return upstream.
  • the effect of the spring is then braked or blocked.
  • the lever 70 the user will not only rotate the fins 55 annularly, but also erase the grip of the corners of the tongue 56 on the body.
  • the effect of the spring 69 is then exerted, and produces the upstream return, which the user follows with the lever 70. After such an injection, it is possible to act again by rotation of the sleeve, to order a new dose, equal to the first or different from the latter.
  • the lever 70 follows the movement of the ring during the delivery of the dose, hence a visual indication as well as an audible one (by the notches) of the real injection dose. At the end of delivery, the same notches hold the sleeve 50 - ring 60 - lever 70 assembly in the depressed position.
  • a push on the lever 70, towards the inside of the body will first have the effect of releasing the notches of the lever from those of the body, then of urging the longitudinal tongue 56 (FIG. 4) of the fins 55 , to print a slight rotation on its annular guideline to the support of the fins, hence a relaxation of the pressure of the fins 55 on the rod, and consequently the return, under the effect of the elastic return 69, of the ring and of the sleeve to their previous position, before injection, and with the same dose as above.
  • the assembly used has another advantage: it can happen that after having started to unscrew the sleeve, the user no longer knows exactly where it is. It then suffices for him to eject, as lost, the unknown dose, and to repeat the operation.
  • the body is preferably in two parts 21 and 22, pressed one on the other until the separation line 28, leaving the clearance of the notch 22.
  • the syringe is assembled as follows:
  • the fins 55 can be provided with a tongue 56 which is folded in a V (fig. 10A and 10B) to ensure the braking action by its corners 56H and 56L which engage on the inner wall of the body 2.
  • Another variant consists in doubling the non-return action and the braking action.
  • the fins 55 (fig.llA) provide only the non-return action on the rod 40.
  • the tongue 56B is folded. Its corners brake by pressing on the body 2.
  • two opposite fins can be provided instead of the four described.
  • a curved cross section of the rod 40 can be accommodated.

Abstract

The device for administering controlled doses is comprised of an elongate hollow body (2) appropriate to be housed inside a refill of fluid product, actuated by pushing a pusher slidingly mounted within the body (2) on the upstream side of the refill, by means of a pushrod (40), limiter means (23, 29) to limit the authorized excursion of the pusher (4) towards the refill, and anti-return means (55) for the pusher. The push-rod (40) has a cylindrical or prismatic shape, and the anti-return means is comprised at least of a semi-rigid wing inclined to the axis (55) cooperating in a buttressing way with the side surface of said pushrod (40).

Description

DISPOSITIF DE DELIVRANCE DE DOSES A USAGE UNIQUE SINGLE USE DOSAGE DELIVERY DEVICE
δδ
L'invention concerne la délivrance de doses contrôlées, d'un produit fluide, c'est à dire liquide ou pâteux.The invention relates to the delivery of controlled doses of a fluid product, that is to say liquid or pasty.
Bien qu'elle soit susceptible de très nombreuses applications 0 dans divers domaines, elle trouve un intérêt particulier pour les injections répétitives effectuées par les patients eux-mêmes, comme c'est le cas notamment pour certains patients avec deAlthough it is capable of very numerous applications in various fields, it is of particular interest for repetitive injections carried out by the patients themselves, as is the case in particular for certain patients with
1 ' insuline .1 insulin.
5 On connaît déjà un tel dispositif de délivrance de doses contrôlées, comprenant :There is already known such a device for delivering controlled doses, comprising:
- un corps creux allongé propre à loger intérieurement une recharge d'un produit liquide ou pâteux, actionné par poussée, 0 ainsi qu'à recevoir du côté aval de la recharge un embout de délivrance ,- an elongated hollow body capable of internally housing a refill of a liquid or pasty product, actuated by pushing, 0 as well as receiving on the downstream side of the refill a delivery nozzle,
- un poussoir monté à coulissement dans le corps au côté amont αe ιa recharge, avec une tige de poussée,- a pusher mounted to slide in the body at the upstream side αe ιa refill, with a push rod,
- des moyens limiteurs de l'excursion permise au poussoir vers la recharge, pour définir la dose.- means limiting the excursion allowed to the pusher towards the refill, to define the dose.
Les dispositifs connus sont pour la plupart de structure très 30 complexe. Leur constitution est donc difficilement compatible avec le concept de seringue jetable, qui s'impose pour différentes raisons : éviter des contaminations dans le domaine médical, ou plus simplement agrément d'utilisation, s'il s'agit par exemple de la distribution d'une colle.The known devices are for the most part very complex in structure. Their constitution is therefore hardly compatible with the concept of disposable syringe, which is essential for various reasons: to avoid contamination in the medical field, or more simply approval of use, if it is for example the distribution of glue.
-JD-JD
Par ailleurs, la plupart des dispositifs connus nécessitent une nouvelle définition de la dose pour chaque utilisation. Ceci en complique l'utilisation, et comporte des risques d'erreurs lors d'applications médicales.Furthermore, most of the known devices require a new definition of the dose for each use. This in complicates use, and carries the risk of errors during medical applications.
Il est en outre nécessaire que la définition de la dose soit précise, et de préférence vérifiable par plusieurs moyens, y compris par exemple des moyens acoustiques pour les non-voyants.It is also necessary that the definition of the dose be precise, and preferably verifiable by several means, including for example acoustic means for the blind.
Enfin, il peut arriver qu'en cours de définition de la dose, l'utilisateur ne sache plus où il en est. Ceci peut conduire à un dosage erroné, voire à 1'endommagement du dispositif.Finally, it may happen that during the definition of the dose, the user no longer knows where he is. This can lead to incorrect dosing or even damage to the device.
La présente invention a principalement pour but d'apporter des solutions convenables aux difficultés relevées plus haut.The main object of the present invention is to provide suitable solutions to the difficulties noted above.
Selon une première caractéristique de l'invention, la tige de poussée est de forme cylindrique ou prismatique (en principe lisse ) et le moyen anti-retour comprend au moins une ailette semi-rigide inclinée sur l'axe, et coopérant à arc-boutement avec la surface latérale de ladite tige de poussée. Par ailette semi- rigide, on entend une ailette qui est intrinsèqument flexible du fait de 1'arc-boutement. Il s'est avéré que ce moyen anti- retour permet déjà de simpli ier considérablement la construction du dispositif.According to a first characteristic of the invention, the push rod is of cylindrical or prismatic shape (in principle smooth) and the non-return means comprises at least one semi-rigid fin inclined on the axis, and cooperating with bracing with the lateral surface of said push rod. By semi-rigid fin means a fin which is inherently flexible due to the bracing. It turned out that this non-return means already considerably simpli ies the construction of the device.
£n pratique, la ou les ailettes forment anti-retour vers l'amont pour la tige de poussée par rapport au corps. De préférence, cette tige de poussée coopère avec une pluralité d'ailettes régulièrement réparties, convergeant vers le centre en direction de l'embout du dispositif, avec une géométrie correspondant à celle de la section droite de la tige. Ainsi, les ailettes assurent, en même temps que la fonction anti-retour, celle de maintien de la tige à l'intérieur du corps.£ n practical, the or the fins form non-return upstream for the push rod relative to the body. Preferably, this push rod cooperates with a plurality of regularly distributed fins, converging towards the center in the direction of the end piece of the device, with a geometry corresponding to that of the cross section of the rod. Thus, the fins provide, at the same time as the non-return function, that of holding the rod inside the body.
Ce maintien est encore mieux assuré lorsqu'on utilise la caractéristique de l'invention ci-après.This maintenance is even better ensured when using the characteristic of the invention below.
Selon celle-ci, le poussoir coopère avec la tige de poussée également par l'intermédiaire d'au moins une autre ailette semi- rigide, de préférence une pluralité d'ailettes, inclinées sur l'axe, et coopérant à arc-boutement avec la surface latérale de la tige de poussée, de façon à former également anti-retour, mais cette fois vers l'aval, pour le poussoir par rapport à la tige.According to this, the pusher cooperates with the push rod also by means of at least one other semi-fin. rigid, preferably a plurality of fins, inclined on the axis, and cooperating with bracing with the lateral surface of the push rod, so as to also form non-return, but this time downstream, for the pusher relative to the rod.
De préférence, cette ou ces autres ailettes, régulièrement réparties, convergent vers le centre en direction de l'embout du dispositif, avec une géométrie correspondant à celle de la section droite de la tige. Ainsi, ces ailettes, en même temps que la fonction anti-retour, contribuent au maintien de la tige à l'intérieur du corps.Preferably, this or these other fins, regularly distributed, converge towards the center in the direction of the end piece of the device, with a geometry corresponding to that of the cross section of the rod. Thus, these fins, at the same time as the non-return function, contribute to the maintenance of the rod inside the body.
Ce second jeu d'ailettes est en principe monté sur un même support. Celui-ci peut être également rendu déformable, par pivotement autour d'une ligne directrice annulaire, de façon à favoriser le retour vers l'amont des secondes ailettes par rapport à la tige. On peut ainsi commander la mise en oeuvre d'un nouveau dosage. Dans la mesure où le poussoir retourne vers l'amont avec ces secondes ailettes, on mémorise la dose en cours, si c'est souhaité.This second set of fins is in principle mounted on the same support. It can also be made deformable, by pivoting around an annular guideline, so as to favor the return upstream of the second fins relative to the rod. We can thus order the implementation of a new dosage. Insofar as the pusher returns upstream with these second fins, the current dose is memorized, if desired.
Il est également avantageux de prévoir des moyens de freinage, formant anti-retour vers l'amont des secondes ailettes par rapport au corps. De préférence, un effort élastique de compression s'exerce entre ces secondes ailettes et le corps.It is also advantageous to provide braking means, forming a non-return upstream of the second fins relative to the body. Preferably, an elastic compression force is exerted between these second fins and the body.
D'autres caractéristiques et avantages de l'invention apparaîtront à l'examen de la description détaillée ci-après, ainsi que des dessins annexés, sur lesquels :Other characteristics and advantages of the invention will appear on examining the detailed description below, as well as the appended drawings, in which:
- la figure 1 est une vue longitudinale en coupe d'un dispositif selon l'invention;- Figure 1 is a longitudinal sectional view of a device according to the invention;
- la figure 2 est une vue partielle agrandie correspondant à la partie droite de la figure 1, où apparaît l'essentiel des moyens selon l'invention; - la figure 3 est un schéma simplifié permettant de faciliter la compréhension des mécanismes visibles sur les figures 1 et 2;- Figure 2 is an enlarged partial view corresponding to the right part of Figure 1, where appears most of the means according to the invention; - Figure 3 is a simplified diagram to facilitate the understanding of the mechanisms visible in Figures 1 and 2;
- les figures 4 et 4A sont deux vues partielles en perspective détaillant la structure des moyens anti-retour à ailettes métalliques, en deux modes de réalisation respectifs;- Figures 4 and 4A are two partial perspective views detailing the structure of the non-return means with metal fins, in two respective embodiments;
les figures 5A à 5C illustrent un mode de réalisation particulier de la tige de poussée;FIGS. 5A to 5C illustrate a particular embodiment of the push rod;
les figures 6A à 6D illustrent un mode de réalisation particulier du manchon;FIGS. 6A to 6D illustrate a particular embodiment of the sleeve;
les figures 7A à 7C illustrent un mode de réalisation particulier du corps du dispositif, en sa partie droite;FIGS. 7A to 7C illustrate a particular embodiment of the body of the device, in its right part;
- la figure 8 illustre un premier mode de réalisation de la bague avec son levier;- Figure 8 illustrates a first embodiment of the ring with its lever;
- les figures 9A à 9D illustrent une variante de réalisation particulier de la bague avec son levier formant dispositif de freinage et action crantée;- Figures 9A to 9D illustrate a particular embodiment of the ring with its lever forming a braking device and notched action;
- les figures 10A à 10C illustrent une variante de réalisation des ailettes 55 et du levier 7û; et- Figures 10A to 10C illustrate an alternative embodiment of the fins 55 and the lever 7û; and
- les figures 11A et 11B illustrent une autre variante de réalisation des ailettes 55, en deux pièces.- Figures 11A and 11B illustrate another alternative embodiment of the fins 55, in two parts.
Les dessins annexés sont pour l'essentiel de caractère certain. En conséquence, ils sont à considérer comme parties intégrantes de la présente description, et pourront servir non seulement à mieux faire comprendre celle-ci, mais aussi pour contribuer à la définition de l'invention, le cas échéant.The attached drawings are essentially of a certain character. Consequently, they are to be considered as integral parts of the present description, and may serve not only to make it better understood, but also to contribute to the definition of the invention, if necessary.
La description détaillée ci-après concerne le cas d'une injection médicamenteuse. On appellera donc dorénavant le dispositif "seringue" . Sur la figure 1, la seringue comprend en partie gauche un logement 1 renfermant une cartouche ou carpule 3 contenant par exemple de l'insuline. Cette carpule est munie, à une extrémité, d'un piston d'actionnement 34, et à l'autre d'une tête 32 logeant un opercule traversable par une aiguille. Un porte-aiguille (non représenté) peut venir se fixer en 12 sur le logement 1. Les moyens 12 peuvent être un filetage ou d'autres moyens de fixation.The detailed description below relates to the case of a drug injection. We will henceforth call the device "syringe". In Figure 1, the syringe comprises in the left part a housing 1 containing a cartridge or cartridge 3 containing for example insulin. This cartridge is provided, at one end, with an actuating piston 34, and at the other with a head 32 housing a seal passable by a needle. A needle holder (not shown) can be fixed at 12 to the housing 1. The means 12 can be a thread or other fixing means.
Le logement 1 est fixé par collage, sertissage ou tout autre moyen sur le reste 2 du corps (que l'on appellera ci-après "le corps" ) .The housing 1 is fixed by gluing, crimping or any other means on the rest 2 of the body (which will be called hereinafter "the body").
Ce corps 2 (figures 1, 2 et 7A à 7C ) comprend, à gauche une partie cylindrique 21, suivie d'une partie centrale munie d'une échancrure longitudinale 22 (on y voit sur la figure 7C le levier 70). Après cela, le corps 2 offre un épaulement radial interne 23. De l'autre côté de 1 'épaulement, c'est-à-dire à droite, il définit en 24 un logement, qui peut être muni de rainures longitudinales 24A (figure 7B).This body 2 (FIGS. 1, 2 and 7A to 7C) comprises, on the left, a cylindrical part 21, followed by a central part provided with a longitudinal notch 22 (we see in FIG. 7C the lever 70). After that, the body 2 offers an internal radial shoulder 23. On the other side of the shoulder, that is to say on the right, it defines at 24 a housing, which can be provided with longitudinal grooves 24A (FIG. 7B).
Le poussoir se compose essentiellement de trois parties principales : une tige de poussée 40, un manchon 50 et une bague 60.The pusher essentially consists of three main parts: a push rod 40, a sleeve 50 and a ring 60.
Pour faciliter la description, on considérera dans la suite la tige de poussée comme extérieure à l'ensemble poussoir, bien qu'elle contribue naturellement à la fonction de poussée.In order to facilitate the description, the push rod will be considered below as being external to the pusher assembly, although it naturally contributes to the push function.
Cette tige de poussée 40 (figures SA à 5C) possède une section droite polygonale, par exemple carrée à coins coupés (figure 5C ) . A une extrémité, un embout élargi 42 vient de matière avec la tige 40. A l'autre extrémité est prévu un embout ajouté 41.This push rod 40 (Figures SA to 5C) has a polygonal cross section, for example square with cut corners (Figure 5C). At one end, an enlarged end piece 42 is made in one piece with the rod 40. At the other end is provided an added end piece 41.
Le manchon (figures 6A à 6D) est désigné dans son ensemble par 50. Un épaulement central externe 53 le sépare en deux parties 51 et 54, de forme générale cylindrique. Sa partie de droite 51 est munie d'un filetage externe 52, et d'une extrémité 58 renforcée, adaptée à tourner par rapport à de la tige 40.The sleeve (FIGS. 6A to 6D) is designated as a whole by 50. An external central shoulder 53 separates it into two parts 51 and 54, of generally cylindrical shape. His right part 51 is provided with an external thread 52, and with a reinforced end 58, adapted to rotate relative to the rod 40.
Dans les pièces 51, 53 et 54 sont découpées des lèvres longitudinales 57A et 57B. Celles-ci supportent un téton 57 avec rappel élastique vers l'extérieur. Par coopération avec les rainures axiales 24A du corps ( figure 6C ) , ce téton réalise une indexation de la rotation du manchon, en même temps qu'une indication sonore.In parts 51, 53 and 54 are cut longitudinal lips 57A and 57B. These support a nipple 57 with elastic return to the outside. By cooperation with the axial grooves 24A of the body (FIG. 6C), this stud realizes an indexing of the rotation of the sleeve, at the same time as an audible indication.
Il est surajouté à droite au manchon 50 un capuchon 59 servant simplement à faciliter l'entraînement à rotation de celui-ci.It is added on the right to the sleeve 50 a cap 59 serving simply to facilitate the rotational drive thereof.
La bague 60 (figure 8) est en forme de cylindre allongé, de section droite circulaire. Mais il est prévu en haut un évidement 63, sur lequel vient, comme partie intégrante et en saillie longitudinale, un levier 70. Intérieurement, la bague est munie d'un filetage 64 propre à coopérer avec le filetage 52 du manchon. Le levier 70 fait saillie en surplomb dans l'axe au- dessus de la bague.The ring 60 (FIG. 8) is in the form of an elongated cylinder, of circular cross section. But there is provided at the top a recess 63, on which comes, as an integral part and projecting longitudinally, a lever 70. Internally, the ring is provided with a thread 64 adapted to cooperate with the thread 52 of the sleeve. The lever 70 projects in overhang in the axis above the ring.
Une variante de la bague est illustrée aux figures 9A à 9D. Ici, le corps 61 de la bague offre en haut un méplat 62. Le levier 70 possède une forme spéciale. Du côté de son extrémité (vers la gauche sur les figures), il est fendu en deux parties 71 et 72, qui définissent des crans 75 et 76.A variant of the ring is illustrated in FIGS. 9A to 9D. Here, the body 61 of the ring has a flat portion 62 at the top. The lever 70 has a special shape. On the side of its end (towards the left in the figures), it is split into two parts 71 and 72, which define notches 75 and 76.
Des crantages correspondants 27 et 28 sont prévus sur l'échancrure 22 du corps. Alors que le crantage du corps en 27 et 28 (figure 9D ) est symétrique, on remarque que les crans 75 et 76 du levier sont décalés d'un demi-pas.Corresponding notches 27 and 28 are provided on the notch 22 of the body. While the notching of the body at 27 and 28 (FIG. 9D) is symmetrical, it is noted that the notches 75 and 76 of the lever are offset by half a step.
En outre, il est prévu, sur le levier, au niveau de ces crans, un striage permettant d'agir avec un doigt, comme le pouce, sur le levier 70 à des fins que l'on décrira plus loin.In addition, there is provided, on the lever, at the level of these notches, a rift making it possible to act with a finger, such as the thumb, on the lever 70 for purposes which will be described later.
On revient maintenant aux figures 1 et 2. La partie droite 2 du corps se complète de pièces 29 surajoutées, assurant le logement exact du manchon 50, tout en définissant une butée amont pour celui-ci, à l'opposé de la butée aval 23 déjà décrite.We now return to FIGS. 1 and 2. The right part 2 of the body is completed with superimposed parts 29, ensuring the accommodation exact of the sleeve 50, while defining an upstream stop for the latter, opposite the downstream stop 23 already described.
Du côté de l'extrémité gauche du corps 2, celui-ci loge une pluralité d'ailettes 25, qui prennent appui sur la tige pour former anti-retour vers l'amont, c'est-à-dire vers la droite. En d'autres termes, dès lors que la tige a été enfoncée, elle ne pourra pas revenir en arrière.On the side of the left end of the body 2, it accommodates a plurality of fins 25, which bear on the rod to form a non-return upstream, that is to say to the right. In other words, once the rod has been pushed in, it cannot go back.
A l'extrémité gauche de la bague 50 est également fixé un jeu d'ailettes 55, qui prend également appui sur la tige. Ce jeu d'ailettes a essentiellement pour fonction de commander l'avancée de la tige par poussée de la bague.At the left end of the ring 50 is also fixed a set of fins 55, which also bears on the rod. This set of fins essentially has the function of controlling the advance of the rod by pushing the ring.
Les ailettes 55 (figure 4) sont ici venues de matière sur un anneau métallique, avantageusement muni vers l'arrière une languette axiale 56. La périphérie de l'anneau et/ou la languette 56 peuvent être noyés dans le matériau synthétique de la bague 50. La bague 50 est par exemple surmoulée sur ces parties métalliques.The fins 55 (FIG. 4) are here made of a piece of material on a metal ring, advantageously provided towards the rear with an axial tongue 56. The periphery of the ring and / or the tongue 56 can be embedded in the synthetic material of the ring 50. The ring 50 is for example overmolded on these metal parts.
En variante, la périphérie de l'anneau et/ou la languette 56 peuvent être noyés dans le matériau synthétique du levier 70, par exemple par surmoulage. Dans ce cas, la languette 56 peut former frein, par ses coins qui viennent en prise sur la paroi interne du corps 2. D'autres réalisations du frein sont envisageables.Alternatively, the periphery of the ring and / or the tongue 56 can be embedded in the synthetic material of the lever 70, for example by overmolding. In this case, the tongue 56 can form a brake, by its corners which engage on the internal wall of the body 2. Other embodiments of the brake are conceivable.
Sur la figure 3, on voit d'une façon simplifiée qu'au repos l'épaulement 53 du manchon vient en appui sur la butée aval 23 du corps. C'est la dose zéro, dans le mode de réalisation décrit.In FIG. 3, it can be seen in a simplified manner that at rest the shoulder 53 of the sleeve comes to bear on the downstream stop 23 of the body. This is the zero dose, in the embodiment described.
Un dévissage du manchon par rapport à la bague permet de fixer une dose. A cet effet, des indications précises peuvent être données du côté du bouton de commande 59, avec par exemple affichage d'indications visuelles au niveau de la fenêtre visible en 59A sur la figure 1. Après fixation de la dose voulue, 1'épaulement 53 s'est donc écarté d'une certaine distance par rapport à l'épaulement 23. L'excursion limite est définie par 1*épaulement de gauche de la pièce 29.Unscrewing the sleeve relative to the ring makes it possible to fix a dose. To this end, precise indications can be given on the side of the control button 59, with for example display of visual indications at the level of the window visible at 59A in FIG. 1. After fixing the desired dose, the shoulder 53 has therefore deviated by a certain distance from the shoulder 23. The limit excursion is defined by the left shoulder of the part 29.
Lorsqu'on appuie maintenant sur le bouton 59, l'ensemble manchon 50 et bague 60 va avancer vers la gauche, et les moyens anti- retour 55 vont pousser en correspondance la tige 40, d'où 1'actionnement du piston 34 pour délivrer la dose voulue.When the button 59 is now pressed, the sleeve 50 and ring 60 assembly will advance to the left, and the non-return means 55 will push in correspondence the rod 40, hence the actuation of the piston 34 to deliver the desired dose.
En même temps que la bague avance, le levier 70 (figure 8) fait de même, et progresse dans l'échancrure 22 du corps. Ce mouvement s'effectue à l'encontre du rappel élastique fourni par le ressort 69.At the same time as the ring advances, the lever 70 (FIG. 8) does the same, and progresses in the notch 22 of the body. This movement is carried out against the elastic return provided by the spring 69.
Deux cas peuvent alors se présenter:Two cases can then arise:
- ou bien le ressort 69 est faible, auquel cas son rappel ne suffit pas pour renvoyer l'ensemble manchon 50 - bague 60 à sa position de départ; par le levier 70, agissant sur la languette 56 associée aux ailettes 55 (figure 4), l'usager fait pivoter annulairement les ailettes 55, ce qui facilite le retour amont, que l'usager aide avec le levier 70.- Or the spring 69 is weak, in which case its return is not enough to return the sleeve 50 - ring 60 assembly to its starting position; by the lever 70, acting on the tongue 56 associated with the fins 55 (FIG. 4), the user makes the fins 55 rotate annually, which facilitates the upstream return, which the user helps with the lever 70.
- ou bien le ressort 69 est fort, et son rappel suffit pour renvoyer l'ensemble manchon 50 - bague 60 à sa position de départ; dans ce cas la languette 56 associée aux ailettes 55 (figure 4A), est munie d'un élargissement (vers la droite de lafigure, c'est à dire l'amont) qui la fait venir en prise par ses pointes sur le corps, formant un anti-retour vers l'amont. L'effet du ressort est alors freiné ou bloqué. Par l'action sur le levier 70, l'usager va non seulement faire pivoter annulairement les ailettes 55, mais aussi effacer la prise des coins de la languette 56 sur le corps. L'effet du ressort 69 s'exerce alors, et produit le retour amont, que l'usager suit avec le levier 70. Après une telle injection, il est possible d'agir à nouveau par rotation du manchon, pour commander une nouvelle dose, égale à la première ou différente de celle-ci.- Or the spring 69 is strong, and its return is sufficient to return the sleeve 50 - ring 60 assembly to its starting position; in this case, the tongue 56 associated with the fins 55 (FIG. 4A) is provided with a widening (to the right of the figure, ie upstream) which causes it to come into engagement by its points on the body, forming a non-return upstream. The effect of the spring is then braked or blocked. By the action on the lever 70, the user will not only rotate the fins 55 annularly, but also erase the grip of the corners of the tongue 56 on the body. The effect of the spring 69 is then exerted, and produces the upstream return, which the user follows with the lever 70. After such an injection, it is possible to act again by rotation of the sleeve, to order a new dose, equal to the first or different from the latter.
Ce qui précède fait référence à la réalisation du levier 70 selon la figure 8.The above refers to the production of the lever 70 according to FIG. 8.
Dans la variante de la figure 9, le levier 70 suit le mouvement de la bague lors de la délivrance de la dose, d'où une indication visuelle en même temps que sonore (par les crans) de la dose réelle d'injection. En fin de délivrance, les mêmes crans maintiennent l'ensemble manchon 50 - bague 60 - levier 70 en position enfoncée.In the variant of FIG. 9, the lever 70 follows the movement of the ring during the delivery of the dose, hence a visual indication as well as an audible one (by the notches) of the real injection dose. At the end of delivery, the same notches hold the sleeve 50 - ring 60 - lever 70 assembly in the depressed position.
Selon cette variante, une poussée sur le levier 70, vers l'intérieur du corps, va d'abord avoir pour effet de dégager les crans du levier de ceux du corps, ensuite de solliciter la languette longitudinale 56 (figure 4) des ailettes 55, pour imprimer une légère rotation sur sa ligne directrice annulaire au support des ailettes, d'où un relâchement de la pression des ailettes 55 sur la tige, et par conséquent le renvoi, sous l'effet du rappel élastique 69, de la bague et du manchon à leur position précédente, avant injection, et avec la même dose que précédemment.According to this variant, a push on the lever 70, towards the inside of the body, will first have the effect of releasing the notches of the lever from those of the body, then of urging the longitudinal tongue 56 (FIG. 4) of the fins 55 , to print a slight rotation on its annular guideline to the support of the fins, hence a relaxation of the pressure of the fins 55 on the rod, and consequently the return, under the effect of the elastic return 69, of the ring and of the sleeve to their previous position, before injection, and with the same dose as above.
Le montage utilisé présente un autre avantage : il peut arriver qu'après avoir commencé à dévisser le manchon, l'usager ne sache plus exactement où il en est. Il lui suffit alors d'éjecter, comme perdue,la dose inconnue, et de recommencer l'opération.The assembly used has another advantage: it can happen that after having started to unscrew the sleeve, the user no longer knows exactly where it is. It then suffices for him to eject, as lost, the unknown dose, and to repeat the operation.
De même, si une injection n'a été pratiquée qu'incomplètement, il est envisageable de déterminer la quantité effectivement injectée. On peut alors effectuer aussitôt après l'injection complémentaire voulue.Likewise, if an injection has been given only partially, it is possible to determine the quantity actually injected. We can then perform immediately after the desired additional injection.
Pour l'assemblage de la seringue, le corps est de préférence en deux parties 21 et 22, enfoncées l'une sur l'autre jusqu'à la ligne de séparation 28, en laissant le dégagement de 1'échancrure 22.For the assembly of the syringe, the body is preferably in two parts 21 and 22, pressed one on the other until the separation line 28, leaving the clearance of the notch 22.
L'assemblage de la seringue s'effectue comme suit :The syringe is assembled as follows:
- Introduction de la bague 60 par la droite dans la pièce 22, jusqu'à ce qu'elle vienne sur la butée 23.- Introduction of the ring 60 from the right into the part 22, until it comes to the stop 23.
- Mise en place des ailettes 55, introduction du ressort 69, et mise en place des ailettes 25.- Installation of the fins 55, introduction of the spring 69, and installation of the fins 25.
- Insertion de la pièce 21 sur la pièce 22 avec collage, pour compléter le corps 2.- Insertion of the part 21 on the part 22 with bonding, to complete the body 2.
- Introduction de la tige 40 par la droite jusqu'à ce qu'elle déborde largement par la gauche, puis fixation de la tête 41 sur la tige 40.- Introduction of the rod 40 from the right until it extends well beyond the left, then fixing of the head 41 on the rod 40.
- Introduction du manchon 50 par la gauche dans la pièce 22, avec engagement sur le filetage de la bague 60, puis mise en place de la pièce 29, ainsi que du capuchon 59.- Introduction of the sleeve 50 from the left into the part 22, with engagement on the thread of the ring 60, then fitting of the part 29, as well as of the cap 59.
Fixation d'un embout 1 logeant la carpule 3 voulue à l'extrémité gauche du corps 2.Attachment of a nozzle 1 housing the desired cartridge 3 at the left end of the body 2.
Bien entendu, la présente invention n'est pas limitée aux modes de réalisation ni d'assemblage décrits.Of course, the present invention is not limited to the embodiments or assembly described.
Par exemple, les ailettes 55 (fig. 10C) peuvent être munies d'une languette 56 qui est repliée en V (fig. 10A et 10B) pour assurer l'action de freinage par ses coins 56H et 56L qui viennent en prise sur la paroi interne du corps 2.For example, the fins 55 (fig. 10C) can be provided with a tongue 56 which is folded in a V (fig. 10A and 10B) to ensure the braking action by its corners 56H and 56L which engage on the inner wall of the body 2.
Une autre variante consiste à dédoubler l'action anti-retour et l'action de freinage. Les ailettes 55 (fig.llA) assurent seulement l'action anti-retour sur la tige 40. Une pièce supplémentaire 55B, 56B (fig. 11A et 11B), placée contre la pièce 55, assure l'action de freinage. La languette 56B est pliée. Ses coins freinent par appui sur le corps 2.Another variant consists in doubling the non-return action and the braking action. The fins 55 (fig.llA) provide only the non-return action on the rod 40. An additional part 55B, 56B (fig. 11A and 11B), placed against the part 55, ensures the braking action. The tongue 56B is folded. Its corners brake by pressing on the body 2.
Dans les deux cas, le levier 70, enfoncé, fait cesser l'action de freinage.In both cases, the lever 70, depressed, stops the braking action.
Par ailleurs, en 25 et 55, on peut prévoir deux ailettes opposées, voire une seule, au lieu des quatre décrites. En incurvant le bout des ailettes, on peut accommoder une section droite courbe de la tige 40.Furthermore, at 25 and 55, two opposite fins, or even one, can be provided instead of the four described. By bending the end of the fins, a curved cross section of the rod 40 can be accommodated.
Il est également possible de réaliser des inversions cinématiques: dans la description ci-dessus, le ressort 69 s'oppose à l'injection, et un frein permet de contrôler soit la répétition de la même dose, soit un nouveau dosage; inversement, on peut envisager que la définition de la dose se fasse par dévissage du manchon à l'encontre d'un rappel élastique, avec blocage par un frein, dont le relâchement produirait l'injection, éventuellement assistée à la main par l'opérateur, suivant la force du ressort. It is also possible to carry out kinematic inversions: in the description above, the spring 69 opposes injection, and a brake makes it possible to control either the repetition of the same dose, or a new dosage; conversely, it can be envisaged that the definition of the dose is made by unscrewing the sleeve against an elastic return, locked by a brake, the release of which would produce the injection, possibly assisted by hand by the operator , depending on the force of the spring.

Claims

Revendications claims
1.- Dispositif de délivrance de doses contrôlées, comprenant :1.- Device for delivering controlled doses, comprising:
- un corps creux allongé (1,- an elongated hollow body (1,
2) propre à loger intérieurement une recharge (3) d'un produit fluide, actionnée par poussée (34), ainsi qu'à recevoir (12) du côté aval de la recharge (3) un embout de délivrance, 02) capable of internally housing a refill (3) of a fluid product, actuated by pushing (34), as well as receiving (12) on the downstream side of the refill (3) a delivery nozzle, 0
- un poussoir (4) monté à coulissement dans le corps (2), du côté amont de la recharge, avec une tige de poussée (40),- a pusher (4) slidably mounted in the body (2), on the upstream side of the refill, with a push rod (40),
- des moyens limiteurs (23,29) de l'excursion permise au poussoir 5 (4) vers la recharge (3), et- means limiting (23,29) the excursion allowed to the pusher 5 (4) towards the refill (3), and
- un moyen anti-retour (25,55) du poussoir,- a non-return means (25,55) of the pusher,
caractérisé en ce que la tige de poussée (40) est de forme 0 cylindrique ou prismatique, et en ce que le moyen anti-retour comprend au moins une ailette semi-rigide inclinée sur l'axe (25,55) coopérant à arc-boutement avec la surface latérale de ladite tige de poussée (40).characterized in that the push rod (40) is cylindrical or prismatic in shape 0, and in that the non-return means comprises at least one semi-rigid fin inclined on the axis (25,55) cooperating in an arc buttressing with the lateral surface of said push rod (40).
b . - Dispositif suivant la revendication 1, caractérisé en ce que la ou les ailettes (25) forment anti-retour vers l'amont pour la tige de poussée (40) par rapport au corps (2).b. - Device according to claim 1, characterized in that the or the fins (25) form non-return upstream for the push rod (40) relative to the body (2).
3.- Dispositif suivant l'une des revendications 1 et 2, 0 caractérisé en ce que la tige de poussée (40) coopère avec une pluralité d'ailettes (25), régulièrement réparties, convergeant vers le centre en direction de l'embout du dispositif (1), ces ailettes assurant, en même temps que la fonction anti-retour, celle de maintien de cette tige (40) à l'intérieur du corps (2). 53.- Device according to one of claims 1 and 2, 0 characterized in that the push rod (40) cooperates with a plurality of fins (25), regularly distributed, converging towards the center towards the tip of the device (1), these fins ensuring, at the same time as the non-return function, that of holding this rod (40) inside the body (2). 5
4.- Dispositif suivant l'une des revendications 1 à 3, caractérisé en ce que le poussoir (4) coopère avec la tige de poussée (40), également par l'intermédiaire d'au moins une autre 13 ailette semi-rigide (55) inclinée sur l'axe (5) coopérant à arc- boutement avec la surface latérale de ladite tige de poussée (40), et formant anti-retour vers l'aval pour le poussoir (60) par rapport à la tige (50).4.- Device according to one of claims 1 to 3, characterized in that the pusher (4) cooperates with the push rod (40), also by means of at least one other 13 semi-rigid fin (55) inclined on the axis (5) cooperating with bracing with the lateral surface of said push rod (40), and forming non-return downstream for the pusher (60) by relative to the rod (50).
5.- Dispositif suivant la revendication 4, caractérisé en ce que le poussoir (4) coopère avec une pluralité d'ailettes (55), régulièrement réparties, convergeant vers le centre en direction de l'embout du dispositif (1), ces ailettes assurant, en même temps que la fonction anti-retour, celle de maintien de la tige (40) par rapport au poussoir (4).5.- Device according to claim 4, characterized in that the pusher (4) cooperates with a plurality of fins (55), regularly distributed, converging towards the center towards the tip of the device (1), these fins ensuring, at the same time as the non-return function, that of holding the rod (40) relative to the pusher (4).
6.- Dispositif suivant l'une des revendications 4 et 5, caractérisé en ce que la ou lesdites autres ailettes ( 55 ) sont montées sur un même support (56), deformable sur commande pour favoriser leur retour vers l'amont.6.- Device according to one of claims 4 and 5, characterized in that the or said other fins (55) are mounted on the same support (56), deformable on command to promote their return upstream.
7.- Dispositif suivant la revendication 6, caractérisé en ce qu'il comporte un levier d'actionnement (70) du support deformable, monté dans une échancrure longitudinale du corps (22), accessible de l'extérieur.7.- Device according to claim 6, characterized in that it comprises an actuating lever (70) of the deformable support, mounted in a longitudinal notch of the body (22), accessible from the outside.
8.- Dispositif suivant l'une des revendications 4 à 7, caractérisé en ce que la ou les ailettes ( 55 ) sont solidaires de moyens de ireinage (75,76) formant anti-retour vers l'amont de ces ailettes par rapport au corps.8.- Device according to one of claims 4 to 7, characterized in that the fin (s) (55) are integral with rejection means (75,76) forming non-return upstream of these fins relative to the body.
9.- Dispositif suivant la revendication 8, prise en combinaison avec l'une des revendications 6 et 7 , caractérisé en ce que les moyens de freinage sont également réalisés par le support ( 56 ) deformable .9.- Device according to claim 8, taken in combination with one of claims 6 and 7, characterized in that the braking means are also produced by the support (56) deformable.
10.- Dispositif suivant l'une des revendications 4 à 9, caractérisé en ce que la ou lesdites autres ailettes ( 55 ) sont montées sur un même support (56), soumis à un effort élastique de compression par rapport au corps (2). 1410.- Device according to one of claims 4 to 9, characterized in that the said other fin (s) (55) are mounted on the same support (56), subjected to an elastic compressive force with respect to the body (2) . 14
11.- Dispositif suivant la revendication 10, caractérisé en ce que le rappel élastique (69) s'exerce entre les ailettes (55) et le corps (ailettes 25), vers l'amont.11.- Device according to claim 10, characterized in that the elastic return (69) is exerted between the fins (55) and the body (fins 25), upstream.
5 12.- Dispositif suivant l'une des revendications 4 à 11, caractérisé, en ce que le poussoir (4) comporte un manchon (50) et une bague ( 60 ) .5 12.- Device according to one of claims 4 to 11, characterized in that the pusher (4) comprises a sleeve (50) and a ring (60).
13.- Dispositif suivant la revendication 12, caractérisé en ce 0 que la ou lesdites autres ailettes (55) sont solidaires de la bague ( 60 ) .13.- Device according to claim 12, characterized in that the said one or more other fins (55) are integral with the ring (60).
14.- Dispositif suivant l'une des revendications 12 et 13, caractérisé en ce que le manchon (50) est muni d'un épaulement 5 (53), mobile d'un côté d'une butée (23) du corps.14.- Device according to one of claims 12 and 13, characterized in that the sleeve (50) is provided with a shoulder 5 (53), movable on one side of a stop (23) of the body.
15.- Dispositif suivant l'une des revendications 12 à 14, caractérisé en ce que le manchon ( 50 ) est muni au moins en partie de sections de filetage périphérique (52), tandis que la bague 0 ( 60 ) est munie de sections de filetage ( 64 ) coopérant avec celles du manchon, la rotation du manchon (50) avec translation par rapport à la bague (60) permettant la fixation d'une dose.15.- Device according to one of claims 12 to 14, characterized in that the sleeve (50) is provided at least in part with peripheral thread sections (52), while the ring 0 (60) is provided with sections thread (64) cooperating with those of the sleeve, the rotation of the sleeve (50) with translation relative to the ring (60) allowing the fixing of a dose.
16.- Dispositif suivant l'une des revendications 12 à 15, 5 caractérisé en ce que le manchon comporte, sur sa périphérie, des moyens crantés formant bruiteurs et/ou indicateurs visuels.16.- Device according to one of claims 12 to 15, 5 characterized in that the sleeve comprises, on its periphery, notched means forming noise and / or visual indicators.
17.- Dispositif suivant l'une des revendications précédentes, caractérisé en ce que le corps (2) est réalisé par au moins une 0 pièce, assemblable sur le logement (1) de la recharge (3). 17.- Device according to one of the preceding claims, characterized in that the body (2) is produced by at least one 0 piece, which can be assembled on the housing (1) of the refill (3).
PCT/FR1992/000037 1991-01-17 1992-01-16 Device for dispensing controlled dose units, particularly of the disposable type WO1992012747A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9100524A FR2671729A1 (en) 1991-01-17 1991-01-17 DEVICE FOR DELIVERING CONTROLLED DOSES, PARTICULARLY OF THE DISPOSABLE INSULIN SYRINGE TYPE.
FR91/00524 1991-01-17

Publications (1)

Publication Number Publication Date
WO1992012747A1 true WO1992012747A1 (en) 1992-08-06

Family

ID=9408796

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR1992/000037 WO1992012747A1 (en) 1991-01-17 1992-01-16 Device for dispensing controlled dose units, particularly of the disposable type

Country Status (2)

Country Link
FR (1) FR2671729A1 (en)
WO (1) WO1992012747A1 (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5480381A (en) * 1991-08-23 1996-01-02 Weston Medical Limited Needle-less injector
WO1996007443A1 (en) * 1994-09-08 1996-03-14 Owen Mumford Limited Improvements relating to injection devices
US6569126B1 (en) * 1997-07-14 2003-05-27 Novo Nordisk A/S Cylinder ampoule
WO2011092520A3 (en) * 2010-02-01 2011-09-22 Barry Peter Liversidge Safety device mounting arrangement
US8118781B2 (en) 2006-04-19 2012-02-21 Novo Nordisk A/S Fluid infusion system, a method of assembling such system and drug reservoir for use in the system
US8551045B2 (en) 2006-04-19 2013-10-08 Novo Nordisk A/S Fluid infusion system, a method of assembling such system and drug reservoir for use in the system

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19945397C2 (en) 1999-09-22 2001-07-19 Disetronic Licensing Ag Device for the dosed administration of an injectable product
EP2547385A1 (en) * 2010-03-16 2013-01-23 Sanofi-Aventis Deutschland GmbH Drug delivery device

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988008725A1 (en) * 1987-05-08 1988-11-17 Wilhelm Haselmeier Gmbh + Co. Injection device with a loading element and a second setting element
EP0293572A1 (en) * 1987-04-07 1988-12-07 D.C.P. Af 1988 A/S Unit for dosing liquids from a container
US4946441A (en) * 1988-07-21 1990-08-07 Maurice Laderoute Limited use hypodermic syringe
EP0416975A1 (en) * 1989-08-25 1991-03-13 André Taddei Portable device to perform multiple dosages of a liquid or pasty product
EP0450905A1 (en) * 1990-04-04 1991-10-09 Eli Lilly And Company Dose indicating injection pen
EP0327910B1 (en) * 1988-02-10 1992-04-15 D.C.P. Af 1988 A/S A dosage unit for dosing a number of measured quantities of a liquid, such as an insulin preparation, from a cartridge

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0293572A1 (en) * 1987-04-07 1988-12-07 D.C.P. Af 1988 A/S Unit for dosing liquids from a container
WO1988008725A1 (en) * 1987-05-08 1988-11-17 Wilhelm Haselmeier Gmbh + Co. Injection device with a loading element and a second setting element
EP0327910B1 (en) * 1988-02-10 1992-04-15 D.C.P. Af 1988 A/S A dosage unit for dosing a number of measured quantities of a liquid, such as an insulin preparation, from a cartridge
US4946441A (en) * 1988-07-21 1990-08-07 Maurice Laderoute Limited use hypodermic syringe
EP0416975A1 (en) * 1989-08-25 1991-03-13 André Taddei Portable device to perform multiple dosages of a liquid or pasty product
EP0450905A1 (en) * 1990-04-04 1991-10-09 Eli Lilly And Company Dose indicating injection pen

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5480381A (en) * 1991-08-23 1996-01-02 Weston Medical Limited Needle-less injector
WO1996007443A1 (en) * 1994-09-08 1996-03-14 Owen Mumford Limited Improvements relating to injection devices
US6569126B1 (en) * 1997-07-14 2003-05-27 Novo Nordisk A/S Cylinder ampoule
US8118781B2 (en) 2006-04-19 2012-02-21 Novo Nordisk A/S Fluid infusion system, a method of assembling such system and drug reservoir for use in the system
US8551045B2 (en) 2006-04-19 2013-10-08 Novo Nordisk A/S Fluid infusion system, a method of assembling such system and drug reservoir for use in the system
WO2011092520A3 (en) * 2010-02-01 2011-09-22 Barry Peter Liversidge Safety device mounting arrangement

Also Published As

Publication number Publication date
FR2671729A1 (en) 1992-07-24

Similar Documents

Publication Publication Date Title
EP1485153B1 (en) Needle protection device for a syringe and an injection device comprising a syringe and said protection device
EP0773806B1 (en) Metering instrument, particularly for injecting medicinal liquids
CH620126A5 (en)
EP1053037A1 (en) Device for automatic injection of a dose of medicinal product
WO2016193620A1 (en) Auto-injector with a system for delaying the device indicating the removal of the auto-injector
EP1682207A2 (en) Protected injection syringe device
EP1532997B1 (en) Needle protecting device for a carpule
WO1996004991A1 (en) Pipette for distributing successive volumes of a liquid
WO2003045481A1 (en) Safety device for disposable parenteral route injection syringe
WO1992012747A1 (en) Device for dispensing controlled dose units, particularly of the disposable type
FR2978021A1 (en) SYSTEM FOR PACKAGING AND APPLYING A PRODUCT, IN PARTICULAR A COSMETIC PRODUCT
BE654563A (en)
FR3072313B1 (en) DEVICE FOR DISPENSING FLUID PRODUCT
FR2467149A1 (en) DISPENSER-DOSER FOR PASTY AND LIQUID PRODUCTS
CH333737A (en) Hypodermic syringe
EP3302646B1 (en) Auto-injector with a delay device comprising an epicyclic gear train
FR2637512A1 (en) Device for the automatic delivery of a product or of any object
WO2017109333A1 (en) Automatic injection device having an improved cam path
EP1177005B1 (en) Disposable safety syringe
WO2016193624A1 (en) Auto-injector
WO2020099766A1 (en) Device for dispensing a fluid product
EP3852845B1 (en) Autoinjector
FR2778852A1 (en) Syringe with retractable needle
BE1005801A4 (en) Syringe for medical use
BE1007043A3 (en) SINGLE SELF-DESTRUCTIVE SYRINGE.

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): JP US

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FR GB GR IT LU MC NL SE

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
122 Ep: pct application non-entry in european phase