US5658308A - Bioactive occlusion coil - Google Patents

Bioactive occlusion coil Download PDF

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Publication number
US5658308A
US5658308A US08/566,799 US56679995A US5658308A US 5658308 A US5658308 A US 5658308A US 56679995 A US56679995 A US 56679995A US 5658308 A US5658308 A US 5658308A
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United States
Prior art keywords
coil
occlusion
strands
bioactive
occlusion coil
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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US08/566,799
Inventor
Edward J. Snyder
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Target Therapeutics Inc
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Target Therapeutics Inc
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Publication date
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Priority to US08/566,799 priority Critical patent/US5658308A/en
Assigned to TARGET THERAPEUTICS, INC. reassignment TARGET THERAPEUTICS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: SNYDER, EDWARD J.
Priority to CA002191782A priority patent/CA2191782A1/en
Priority to EP96308702A priority patent/EP0778005A1/en
Priority to AU74132/96A priority patent/AU679419B1/en
Priority to NO965154A priority patent/NO965154L/en
Priority to JP8324417A priority patent/JP2908363B2/en
Application granted granted Critical
Publication of US5658308A publication Critical patent/US5658308A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/1214—Coils or wires
    • A61B17/12145—Coils or wires having a pre-set deployed three-dimensional shape
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/1214—Coils or wires
    • A61B17/1215—Coils or wires comprising additional materials, e.g. thrombogenic, having filaments, having fibers, being coated

Definitions

  • This invention relates to a medical device for forming an embolism within the vasculature of a patient. More particularly, it concerns an occlusion coil comprised of a helical wound elongated coil of a biocompatible metal and one or more strands of a bioactive material extending axially through the coil.
  • Intravascular occlusion coils are used to form blockages within the vasculature for controlling internal bleeding, treating aneurysms, or reducing blood flow to tumors. These coils are typically placed at the site of the desired blockage by means of a catheter.
  • U.S. Pat. No. 5,226,911 describes a helical metal coil that has one or more fiber bundles having a serpentine configuration, the loops of which extend about the individual windings of the coil.
  • U.S. Pat. No. 5,417,708 shows a helical coil that has Dacron fibers extending radially from the coil windings.
  • FIG. 5 of U.S. Pat. No. 5,423,849 describes a vasooclusive device composed of a tube made of braided radiopaque fibers having a bundle of radiolucent fibers extending axially through the lumen of the braided tube. The ends of the fibers that form the bundle may be heat sealed.
  • the present invention is an occlusion coil comprising an elongated helical coil of a biocompatible metal having a plurality of helically wound, axially spaced windings and at least one strand of a bioactive (typically thrombogenic) material extending axially through the coil.
  • FIG. 1 is a perspective view of one embodiment of the invention
  • FIG. 2 is a cross-sectional view of the embodiment of FIG. 1;
  • FIG. 3 is a perspective view of another embodiment of the invention.
  • FIGS. 1 and 2 show one embodiment of the inventive device.
  • the device generally designated 10
  • Occlusion coil 10 is composed of two principal elements: an elongated helical coil 11 and a plurality of strands or filaments 12 of a bioactive material extending axially through the open core of coil 11.
  • Coil 11 is a cylindrical helix made from a biocompatible metallic wire.
  • metals that may be used to make the coil are silver, the noble metals such as gold, platinum and palladium and tungsten and alloys of such metals.
  • the helix has a plurality of windings 13 that are axially spaced (i.e., the pitch of the windings is greater than the diameter of the wire).
  • the device shown in FIGS. 1 and 2 has a circular cross-section, it could also have other cross-sectional shapes (e.g. rectangular, oval, square, triangular).
  • the diameter of the wire will normally be 0.01 mm to 0.07 mm, preferably 0.02 mm to 0.07 mm.
  • the diameter of the helical coil will usually be 0.2 mm to 1.0 mm, preferably 0.35 mm to 0.5 mm.
  • the pitch, p, of the windings will usually be less than twice the diameter of the wire.
  • the pitch may be uniform or nonuniform along the length of the coil.
  • the length of the coil will normally be 0.2 to 100 cm, more usually 0.5 to 40.0 cm.
  • Strands 12 extend axially through the open central core of the helix. Although four strands are shown in the depicted embodiment, it will be appreciated that fewer or greater strands may be employed depending upon the inner diameter of the helix and the dimensions of the strands. The number/size of the strand(s) should not be such as to impede the flow of blood into the central core of the helix. Generally it is desirable to use a large number of small dimensioned strands so as to provide a large thrombogenic surface area.
  • the ends of the strands are preferably bound together such as by thermal fusion, adhesives or mechanical means such as by tying or fastening with a fastening member. Preferably the ends are bound together in a fashion that renders them atraumatic to the vessel into which the occlusion coil is placed.
  • the strands are generally bioactive in some way. Included in this bioactivity are thrombogenicity and fibrogenicity. Many fibers, including those listed elsewhere herein, are thrombogenic when first placed in contact with blood and are fibrogenic after longer contact with blood fluids.
  • the fibers used in this invention may also be used as carriers for various therapeutic materials, e.g., drugs or growth factors, either through chemical bonding or by simply soaking the device in a solution of the material.
  • the cross-sectional shape of the strands is not critical and may be regular (e.g. circular, rectangular, square, triangular) or irregular.
  • the mean diameter of the strands is not critical but should be small enough to place a significant number of strands within the interior of the coil.
  • the number of strands will usually be in the range of one to several hundred or more, but preferably 25 to 500.
  • the strands may be linear, sinusoidal, crimped or of other axial configuration.
  • the strand(s) are made of one or more natural or synthetic thrombogenic polymers.
  • thrombogenic polymers are high density polyethylene, silk, polyurethane, polyesters such as nylon or polyethylene terephthalate, polyglycolic acid, polylactic acid, etc.
  • the strands may be made of a single homogeneous material or be formed of layers.
  • the strand(s) may have a nonthrombogenic core coated with a thrombogenic polymer.
  • the strands are made of polyethylene or polyethylene terephthalate.
  • FIG. 3 depicts another embodiment, generally designated 20, of the occlusion coil of the invention.
  • Occlusion coil 20 is also composed of an elongated helical coil 21 and a plurality of strands 22 extending axially through coil 21.
  • Coil 20 differs from coil 10 in that it is a conical helix rather than a cylindrical helix, and it includes a plurality of radially extending filaments 23 attached to the windings of the coil. Filaments 23 enhance the ability of the coil to occlude the site at which the coil is placed.
  • Filaments 23 may be made of a bioactive or nonbioactive material.
  • the occlusion coils of the invention may be made using conventional equipment and procedures.
  • the helical coils may be prepared by wrapping a suitable wire about a cylindrical or conical mandrel.
  • the strand(s) are then placed axially through the core of the helix and, if a multiplicity of strands are employed, their ends bound by heat, adhesives, or mechanical means.
  • Radial filaments may be attached to the windings of the helix by tying or with adhesives.

Abstract

A thrombogenic occlusion coil for occluding a blood vessel comprising a helical metallic coil having a plurality of axially spaced windings and a plurality of strands of a thrombogenic polymer extending axially through the central core of the coil, the ends of the strands being bound together.

Description

TECHNICAL FIELD OF THE INVENTION
This invention relates to a medical device for forming an embolism within the vasculature of a patient. More particularly, it concerns an occlusion coil comprised of a helical wound elongated coil of a biocompatible metal and one or more strands of a bioactive material extending axially through the coil.
BACKGROUND OF THE INVENTION
Intravascular occlusion coils are used to form blockages within the vasculature for controlling internal bleeding, treating aneurysms, or reducing blood flow to tumors. These coils are typically placed at the site of the desired blockage by means of a catheter.
Several patents describe occlusive devices that include strands or fibers. U.S. Pat. No. 5,226,911 describes a helical metal coil that has one or more fiber bundles having a serpentine configuration, the loops of which extend about the individual windings of the coil. U.S. Pat. No. 5,417,708 shows a helical coil that has Dacron fibers extending radially from the coil windings. FIG. 5 of U.S. Pat. No. 5,423,849 describes a vasooclusive device composed of a tube made of braided radiopaque fibers having a bundle of radiolucent fibers extending axially through the lumen of the braided tube. The ends of the fibers that form the bundle may be heat sealed.
DISCLOSURE OF THE INVENTION
The present invention is an occlusion coil comprising an elongated helical coil of a biocompatible metal having a plurality of helically wound, axially spaced windings and at least one strand of a bioactive (typically thrombogenic) material extending axially through the coil.
When placed in a blood vessel, blood flows through the spaces between the windings into contact with the strand(s) of thrombogenic material. That material promotes thrombosis and hastens occlusion of the vessel.
BRIEF DESCRIPTION OF THE DRAWINGS
In the drawings, which are not to scale:
FIG. 1 is a perspective view of one embodiment of the invention;
FIG. 2 is a cross-sectional view of the embodiment of FIG. 1; and
FIG. 3 is a perspective view of another embodiment of the invention.
MODES FOR CARRYING OUT THE INVENTION
FIGS. 1 and 2 show one embodiment of the inventive device. As shown in these Figures, the device, generally designated 10, is an occlusion coil. Occlusion coil 10 is composed of two principal elements: an elongated helical coil 11 and a plurality of strands or filaments 12 of a bioactive material extending axially through the open core of coil 11.
Coil 11 is a cylindrical helix made from a biocompatible metallic wire. Examples of metals that may be used to make the coil are silver, the noble metals such as gold, platinum and palladium and tungsten and alloys of such metals. The helix has a plurality of windings 13 that are axially spaced (i.e., the pitch of the windings is greater than the diameter of the wire). Although the device shown in FIGS. 1 and 2 has a circular cross-section, it could also have other cross-sectional shapes (e.g. rectangular, oval, square, triangular). The diameter of the wire will normally be 0.01 mm to 0.07 mm, preferably 0.02 mm to 0.07 mm. The diameter of the helical coil will usually be 0.2 mm to 1.0 mm, preferably 0.35 mm to 0.5 mm. The pitch, p, of the windings will usually be less than twice the diameter of the wire. The pitch may be uniform or nonuniform along the length of the coil. The length of the coil will normally be 0.2 to 100 cm, more usually 0.5 to 40.0 cm.
Strands 12 extend axially through the open central core of the helix. Although four strands are shown in the depicted embodiment, it will be appreciated that fewer or greater strands may be employed depending upon the inner diameter of the helix and the dimensions of the strands. The number/size of the strand(s) should not be such as to impede the flow of blood into the central core of the helix. Generally it is desirable to use a large number of small dimensioned strands so as to provide a large thrombogenic surface area. The ends of the strands are preferably bound together such as by thermal fusion, adhesives or mechanical means such as by tying or fastening with a fastening member. Preferably the ends are bound together in a fashion that renders them atraumatic to the vessel into which the occlusion coil is placed.
The strands are generally bioactive in some way. Included in this bioactivity are thrombogenicity and fibrogenicity. Many fibers, including those listed elsewhere herein, are thrombogenic when first placed in contact with blood and are fibrogenic after longer contact with blood fluids. The fibers used in this invention may also be used as carriers for various therapeutic materials, e.g., drugs or growth factors, either through chemical bonding or by simply soaking the device in a solution of the material.
The cross-sectional shape of the strands is not critical and may be regular (e.g. circular, rectangular, square, triangular) or irregular. The mean diameter of the strands is not critical but should be small enough to place a significant number of strands within the interior of the coil. The number of strands will usually be in the range of one to several hundred or more, but preferably 25 to 500. The strands may be linear, sinusoidal, crimped or of other axial configuration.
The strand(s) are made of one or more natural or synthetic thrombogenic polymers. Examples of thrombogenic polymers are high density polyethylene, silk, polyurethane, polyesters such as nylon or polyethylene terephthalate, polyglycolic acid, polylactic acid, etc. The strands may be made of a single homogeneous material or be formed of layers. For instance, the strand(s) may have a nonthrombogenic core coated with a thrombogenic polymer. Preferably the strands are made of polyethylene or polyethylene terephthalate.
FIG. 3 depicts another embodiment, generally designated 20, of the occlusion coil of the invention. Occlusion coil 20 is also composed of an elongated helical coil 21 and a plurality of strands 22 extending axially through coil 21. Coil 20 differs from coil 10 in that it is a conical helix rather than a cylindrical helix, and it includes a plurality of radially extending filaments 23 attached to the windings of the coil. Filaments 23 enhance the ability of the coil to occlude the site at which the coil is placed. Filaments 23 may be made of a bioactive or nonbioactive material.
The occlusion coils of the invention may be made using conventional equipment and procedures. The helical coils may be prepared by wrapping a suitable wire about a cylindrical or conical mandrel. The strand(s) are then placed axially through the core of the helix and, if a multiplicity of strands are employed, their ends bound by heat, adhesives, or mechanical means. Radial filaments may be attached to the windings of the helix by tying or with adhesives.

Claims (8)

I claim:
1. An occlusion coil for occluding an opening within the human body comprising:
a) an elongated helical coil of a biocompatible metal having a plurality of axial spaced windings; and
b) a plurality of strands of a polymeric, bioactive, occlusion-causing material extending axially through the coil, each such strand having opposing ends, and
wherein the ends of the strands are bound together.
2. The occlusion coil of claim 1 wherein the bioactive material is thrombogenic.
3. The occlusion coil of claim 1 wherein the bioactive material is fibrogenic.
4. The occlusion coil of claim 1 wherein the bioactive material comprises 25 to 500 strands.
5. The occlusion coil of claim 1 wherein the helical coil is a cylindrical helical coil.
6. The occlusion coil of claim 1 wherein said bioactive material is high density polyethylene, polyethylene terephthalate, or silk.
7. The occlusion coil of claim 1 further including
(c) a plurality of radially extending fibers attached to said windings.
8. The occlusion coil of claim 1 wherein the length of the helical coil is 0.02 to 100 cm.
US08/566,799 1995-12-04 1995-12-04 Bioactive occlusion coil Expired - Lifetime US5658308A (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
US08/566,799 US5658308A (en) 1995-12-04 1995-12-04 Bioactive occlusion coil
CA002191782A CA2191782A1 (en) 1995-12-04 1996-11-29 Bioactive occlusion coil
EP96308702A EP0778005A1 (en) 1995-12-04 1996-12-02 Bioactive occlusion coil
AU74132/96A AU679419B1 (en) 1995-12-04 1996-12-03 Bioactive occlusion coil
NO965154A NO965154L (en) 1995-12-04 1996-12-03 Bioactive occlusion coil
JP8324417A JP2908363B2 (en) 1995-12-04 1996-12-04 Bioactive occlusion coil

Applications Claiming Priority (1)

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US08/566,799 US5658308A (en) 1995-12-04 1995-12-04 Bioactive occlusion coil

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US5658308A true US5658308A (en) 1997-08-19

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US (1) US5658308A (en)
EP (1) EP0778005A1 (en)
JP (1) JP2908363B2 (en)
AU (1) AU679419B1 (en)
CA (1) CA2191782A1 (en)
NO (1) NO965154L (en)

Cited By (104)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5836966A (en) * 1997-05-22 1998-11-17 Scimed Life Systems, Inc. Variable expansion force stent
US5911717A (en) * 1997-03-17 1999-06-15 Precision Vascular Systems, Inc. Catheter deliverable thrombogenic apparatus and method
US5980550A (en) * 1998-06-18 1999-11-09 Target Therapeutics, Inc. Water-soluble coating for bioactive vasoocclusive devices
US6013084A (en) * 1995-06-30 2000-01-11 Target Therapeutics, Inc. Stretch resistant vaso-occlusive coils (II)
US6015424A (en) * 1998-04-28 2000-01-18 Microvention, Inc. Apparatus and method for vascular embolization
US6165193A (en) * 1998-07-06 2000-12-26 Microvention, Inc. Vascular embolization with an expansible implant
US6187024B1 (en) 1998-11-10 2001-02-13 Target Therapeutics, Inc. Bioactive coating for vaso-occlusive devices
US20020016613A1 (en) * 1997-12-05 2002-02-07 Kurz Daniel R. Vasoocclusive coil
US6358228B1 (en) 1998-04-07 2002-03-19 Cook Incorporated Vasoocclusive device including asymmetrical pluralities of fibers
US6379379B1 (en) 1998-05-05 2002-04-30 Scimed Life Systems, Inc. Stent with smooth ends
US20020082620A1 (en) * 2000-12-27 2002-06-27 Elaine Lee Bioactive materials for aneurysm repair
US20020099408A1 (en) * 1999-06-02 2002-07-25 Marks Michael P. Method and apparatus for detaching an intracorporeal occlusive device
US20020107534A1 (en) * 2000-09-26 2002-08-08 Dean Schaefer Microcoil vaso-occlusive device with multi-axis secondary configuration
WO2002080782A1 (en) 2001-04-06 2002-10-17 Scimed Life Systems Bioactive occlusion coil
WO2002089863A1 (en) 2001-05-04 2002-11-14 Concentric Medical Bioactive polymer vaso-occlusive device
WO2002096496A1 (en) * 2001-03-30 2002-12-05 Scimed Life Systems, Inc. Embolic devices capable of in-situ reinforcement
US20030018356A1 (en) * 2000-09-26 2003-01-23 Dean Schaefer Microcoil vaso-occlusive device with multi-axis secondary configuration
WO2003015640A1 (en) 2001-08-16 2003-02-27 Scimed Life Systems, Inc. Bioactive occlusion coil
US6605101B1 (en) 2000-09-26 2003-08-12 Microvention, Inc. Microcoil vaso-occlusive device with multi-axis secondary configuration
US6616591B1 (en) 1999-12-08 2003-09-09 Scimed Life Systems, Inc. Radioactive compositions and methods of use thereof
US20030199887A1 (en) * 2002-04-23 2003-10-23 David Ferrera Filamentous embolization device and method of use
US6656200B2 (en) 2000-04-07 2003-12-02 Collagen Matrix, Inc. Embolization device
US20040006362A1 (en) * 2002-07-02 2004-01-08 Dean Schaefer Uniaxial multifilar vaso-occlusive device with high stretch resistance and low buckling strength
US6689141B2 (en) 2000-10-18 2004-02-10 Microvention, Inc. Mechanism for the deployment of endovascular implants
US20040093014A1 (en) * 1998-11-10 2004-05-13 Hanh Ho Bioactive components for incorporation with vaso-occlusive members
US6790218B2 (en) 1999-12-23 2004-09-14 Swaminathan Jayaraman Occlusive coil manufacture and delivery
US20040204701A1 (en) * 2000-10-18 2004-10-14 Brian Cox Mechanism for the deployment of endovascular implants
US20050021074A1 (en) * 2003-07-24 2005-01-27 Elliott Christopher J. Embolic coil
US20050090861A1 (en) * 2003-10-27 2005-04-28 Scimed Life Systems, Inc. Vaso-occlusive devices with in-situ stiffening elements
US20050090856A1 (en) * 2003-10-27 2005-04-28 Scimed Life Systems, Inc. Vasco-occlusive devices with bioactive elements
US20050137623A1 (en) * 2003-12-17 2005-06-23 Jones Donald K. Activatable foam expandable implantable medical device and method of use
US20050149107A1 (en) * 2003-12-17 2005-07-07 Jones Donald K. Activatable bioactive vascular occlusive device and method of use
US20050155610A1 (en) * 2004-01-16 2005-07-21 Mitsuo Satake Bioabsorbable vasoocclusive coil
US20050181155A1 (en) * 2004-02-12 2005-08-18 Share Paul E. Container having barrier properties and method of manufacturing the same
US20050187564A1 (en) * 1999-12-23 2005-08-25 Swaminathan Jayaraman Occlusive coil manufacturing and delivery
US20050228436A1 (en) * 2004-04-08 2005-10-13 Lorenzo Juan A Activatable bioactive vascular occlusive device
US20060036281A1 (en) * 2004-05-21 2006-02-16 Micro Therapeutics, Inc. Metallic coils enlaced with biological or biodegradable or synthetic polymers or fibers for embolization of a body cavity
US20060190076A1 (en) * 2003-11-17 2006-08-24 Taheri Syde A Temporary absorbable venous occlusive stent and superficial vein treatment method
US20060229669A1 (en) * 2005-01-25 2006-10-12 Mirizzi Michael S Method and apparatus for implanting an occlusive structure
US20070299464A1 (en) * 2006-06-15 2007-12-27 Microvention, Inc. Embolization device constructed from expansile polymer
US7326225B2 (en) * 1997-12-05 2008-02-05 Micrus Endovascular Corporation Vasoocclusive device for treatment of aneurysms
US20080051803A1 (en) * 2000-10-30 2008-02-28 Dendron Gmbh Device for the implantation of occlusion spirals
US20080103585A1 (en) * 2004-09-22 2008-05-01 Dendron Gmbh Micro-Spiral Implantation Device
EP1925258A2 (en) 2000-10-18 2008-05-28 MicroVention, Inc. Mechanism for the deployment of endovascular implants
US20080221554A1 (en) * 2007-03-05 2008-09-11 Boston Scientific Scimed, Inc. Deploying Embolic Coils
US20080319532A1 (en) * 2004-09-22 2008-12-25 Ev3, Inc. Medical Implant
EP2008596A1 (en) 1999-10-04 2008-12-31 MicroVention, Inc. Embolic device
US20090125051A1 (en) * 2007-11-13 2009-05-14 Boston Scientific Scimed, Inc. Combination coil and liquid embolic for embolization
US20090204145A1 (en) * 2008-02-12 2009-08-13 Cook Incorporated Spiral occluding device with an occlusion sail
US20090254111A1 (en) * 2005-04-28 2009-10-08 Hermann Monstadt Device for implanting occlusion spirals comprising an interior securing element
US20100036412A1 (en) * 2008-08-06 2010-02-11 Boston Scientific Scimed,Inc. Vaso-occlusive devices with textured surfaces
EP2163212A1 (en) 2001-11-07 2010-03-17 Microvention, Inc. Microcoil vaso-occlusive device with multi-axis secondary configuration
US20100076479A1 (en) * 2004-01-21 2010-03-25 Hermann Monstadt Device for implanting electrically isolated occlusion helixes
US20100160898A1 (en) * 2008-12-19 2010-06-24 Tyco Healthcare Group, Lp Method and apparatus for storage and/or introduction of implant for hollow anatomical structure
US7763077B2 (en) 2003-12-24 2010-07-27 Biomerix Corporation Repair of spinal annular defects and annulo-nucleoplasty regeneration
US7803395B2 (en) 2003-05-15 2010-09-28 Biomerix Corporation Reticulated elastomeric matrices, their manufacture and use in implantable devices
US20100256669A1 (en) * 2005-12-02 2010-10-07 C.R. Bard, Inc. Helical Vena Cava Filter
EP2319430A2 (en) 2001-05-29 2011-05-11 Microvention, Inc. Medical device and method of manufacture
US20110184455A1 (en) * 2009-10-26 2011-07-28 Microvention, Inc. Embolization Device Constructed From Expansile Polymer
US20110212178A1 (en) * 2009-09-24 2011-09-01 Microvention, Inc. Injectable Hydrogel Filaments For Biomedical Uses
US8192480B2 (en) 2007-12-21 2012-06-05 Microvention, Inc. System and method of detecting implant detachment
WO2012082440A1 (en) 2010-12-13 2012-06-21 Microvention, Inc. Stent
US8328860B2 (en) 2007-03-13 2012-12-11 Covidien Lp Implant including a coil and a stretch-resistant member
US20130131711A1 (en) * 2011-11-23 2013-05-23 Microvention, Inc. Embolic Device With Shaped Wire
US8771294B2 (en) 2004-11-26 2014-07-08 Biomerix Corporation Aneurysm treatment devices and methods
US8777979B2 (en) 2006-04-17 2014-07-15 Covidien Lp System and method for mechanically positioning intravascular implants
US8777978B2 (en) 2006-04-17 2014-07-15 Covidien Lp System and method for mechanically positioning intravascular implants
US8801747B2 (en) 2007-03-13 2014-08-12 Covidien Lp Implant, a mandrel, and a method of forming an implant
US8882796B2 (en) 2002-07-31 2014-11-11 Microvention, Inc. Three element coaxial vaso-occlusive device
US20150094752A1 (en) * 2013-09-30 2015-04-02 Covidien Lp Systems and methods for positioning and compacting a bodily implant
US9017361B2 (en) 2006-04-20 2015-04-28 Covidien Lp Occlusive implant and methods for hollow anatomical structure
US9023094B2 (en) 2007-06-25 2015-05-05 Microvention, Inc. Self-expanding prosthesis
US20150174381A1 (en) * 2013-12-20 2015-06-25 Microvention, Inc. Expansile Member
US9192389B2 (en) 2013-03-13 2015-11-24 Cook Medical Technologies Llc Occluding device and method of manufacturing occluding devices
US9242070B2 (en) 2007-12-21 2016-01-26 MicronVention, Inc. System and method for locating detachment zone of a detachable implant
US9326774B2 (en) 2012-08-03 2016-05-03 Covidien Lp Device for implantation of medical devices
US9381278B2 (en) 2012-04-18 2016-07-05 Microvention, Inc. Embolic devices
US9456823B2 (en) 2011-04-18 2016-10-04 Terumo Corporation Embolic devices
US9486221B2 (en) 2007-12-21 2016-11-08 Microvision, Inc. Hydrogel filaments for biomedical uses
US9561125B2 (en) 2010-04-14 2017-02-07 Microvention, Inc. Implant delivery device
US9579104B2 (en) 2011-11-30 2017-02-28 Covidien Lp Positioning and detaching implants
US9636118B2 (en) 2014-02-27 2017-05-02 Incumedx, Inc. Embolic framing microcoils
US9687245B2 (en) 2012-03-23 2017-06-27 Covidien Lp Occlusive devices and methods of use
US9713475B2 (en) 2014-04-18 2017-07-25 Covidien Lp Embolic medical devices
US9717503B2 (en) 2015-05-11 2017-08-01 Covidien Lp Electrolytic detachment for implant delivery systems
US9763667B2 (en) 2013-03-14 2017-09-19 Cook Medical Technologies Llc Embolization coil with barbed fiber
US9808256B2 (en) 2014-08-08 2017-11-07 Covidien Lp Electrolytic detachment elements for implant delivery systems
US9814466B2 (en) 2014-08-08 2017-11-14 Covidien Lp Electrolytic and mechanical detachment for implant delivery systems
US9867725B2 (en) 2010-12-13 2018-01-16 Microvention, Inc. Stent
US10058330B2 (en) 2011-05-11 2018-08-28 Microvention, Inc. Device for occluding a lumen
US20180250010A1 (en) * 2017-03-06 2018-09-06 Cook Medical Technologies Llc Filamentary occlusion assembly
US10092663B2 (en) 2014-04-29 2018-10-09 Terumo Corporation Polymers
US10124090B2 (en) 2014-04-03 2018-11-13 Terumo Corporation Embolic devices
US10226533B2 (en) 2014-04-29 2019-03-12 Microvention, Inc. Polymer filaments including pharmaceutical agents and delivering same
US10307168B2 (en) 2015-08-07 2019-06-04 Terumo Corporation Complex coil and manufacturing techniques
US10639396B2 (en) 2015-06-11 2020-05-05 Microvention, Inc. Polymers
US10828039B2 (en) 2016-06-27 2020-11-10 Covidien Lp Electrolytic detachment for implantable devices
US10828037B2 (en) 2016-06-27 2020-11-10 Covidien Lp Electrolytic detachment with fluid electrical connection
US10893868B2 (en) 2012-01-20 2021-01-19 Covidien Lp Aneurysm treatment coils
US10905432B2 (en) * 2018-08-22 2021-02-02 Covidien Lp Aneurysm treatment coils and associated systems and methods of use
US10912569B2 (en) * 2018-08-22 2021-02-09 Covidien Lp Aneurysm treatment coils and associated systems and methods of use
US11051822B2 (en) 2016-06-28 2021-07-06 Covidien Lp Implant detachment with thermal activation
EP4059475A1 (en) 2012-03-16 2022-09-21 Terumo Corporation Stent delivery device
EP4115854A1 (en) 2015-01-12 2023-01-11 Microvention, Inc. Stent

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5935145A (en) * 1998-02-13 1999-08-10 Target Therapeutics, Inc. Vaso-occlusive device with attached polymeric materials
US6296603B1 (en) * 1998-05-26 2001-10-02 Isostent, Inc. Radioactive intraluminal endovascular prosthesis and method for the treatment of aneurysms
US6945980B2 (en) 1998-06-03 2005-09-20 Medtronic, Inc. Multiple loop tissue connector apparatus and methods
US6607541B1 (en) 1998-06-03 2003-08-19 Coalescent Surgical, Inc. Tissue connector apparatus and methods
US6613059B2 (en) 1999-03-01 2003-09-02 Coalescent Surgical, Inc. Tissue connector apparatus and methods
US6514265B2 (en) 1999-03-01 2003-02-04 Coalescent Surgical, Inc. Tissue connector apparatus with cable release
US6641593B1 (en) 1998-06-03 2003-11-04 Coalescent Surgical, Inc. Tissue connector apparatus and methods
US8118822B2 (en) 1999-03-01 2012-02-21 Medtronic, Inc. Bridge clip tissue connector apparatus and methods
US6695859B1 (en) 1999-04-05 2004-02-24 Coalescent Surgical, Inc. Apparatus and methods for anastomosis
US8529583B1 (en) 1999-09-03 2013-09-10 Medtronic, Inc. Surgical clip removal apparatus
US6926730B1 (en) 2000-10-10 2005-08-09 Medtronic, Inc. Minimally invasive valve repair procedure and apparatus
US6551332B1 (en) 2000-03-31 2003-04-22 Coalescent Surgical, Inc. Multiple bias surgical fastener
US8066724B2 (en) 2002-09-12 2011-11-29 Medtronic, Inc. Anastomosis apparatus and methods
US8105345B2 (en) 2002-10-04 2012-01-31 Medtronic, Inc. Anastomosis apparatus and methods
US7182769B2 (en) 2003-07-25 2007-02-27 Medtronic, Inc. Sealing clip, delivery systems, and methods
US20050043749A1 (en) 2003-08-22 2005-02-24 Coalescent Surgical, Inc. Eversion apparatus and methods
US8394114B2 (en) 2003-09-26 2013-03-12 Medtronic, Inc. Surgical connection apparatus and methods
US7879047B2 (en) 2003-12-10 2011-02-01 Medtronic, Inc. Surgical connection apparatus and methods
US20060155324A1 (en) * 2005-01-12 2006-07-13 Porter Stephen C Vaso-occlusive devices with attached polymer structures
DE102007038446A1 (en) 2007-08-14 2009-02-19 pfm Produkte für die Medizin AG Embolisiereinrichtung
US8177836B2 (en) 2008-03-10 2012-05-15 Medtronic, Inc. Apparatus and methods for minimally invasive valve repair
US8518060B2 (en) 2009-04-09 2013-08-27 Medtronic, Inc. Medical clip with radial tines, system and method of using same
US8668704B2 (en) 2009-04-24 2014-03-11 Medtronic, Inc. Medical clip with tines, system and method of using same
DE202015102060U1 (en) 2015-04-24 2016-07-27 Pfm Medical Ag A medical implant for occluding a defect opening, vessel, organ passage, or other opening in a human or animal body

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4798606A (en) * 1985-02-26 1989-01-17 Corvita Corporation Reinforcing structure for cardiovascular graft
US5226911A (en) * 1991-10-02 1993-07-13 Target Therapeutics Vasoocclusion coil with attached fibrous element(s)
WO1994010936A1 (en) * 1992-11-18 1994-05-26 Target Therapeutics, Inc. Ultrasoft embolism devices and process for using
US5342348A (en) * 1992-12-04 1994-08-30 Kaplan Aaron V Method and device for treating and enlarging body lumens
US5417708A (en) * 1994-03-09 1995-05-23 Cook Incorporated Intravascular treatment system and percutaneous release mechanism therefor
US5423849A (en) * 1993-01-15 1995-06-13 Target Therapeutics, Inc. Vasoocclusion device containing radiopaque fibers
US5443454A (en) * 1992-12-09 1995-08-22 Terumo Kabushiki Kaisha Catheter for embolectomy
WO1995025480A1 (en) * 1994-03-18 1995-09-28 Cook Incorporated Helical embolization coil
US5462523A (en) * 1993-05-18 1995-10-31 Target Therapeutics, Inc. Drug delivery system

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4798606A (en) * 1985-02-26 1989-01-17 Corvita Corporation Reinforcing structure for cardiovascular graft
US5226911A (en) * 1991-10-02 1993-07-13 Target Therapeutics Vasoocclusion coil with attached fibrous element(s)
WO1994010936A1 (en) * 1992-11-18 1994-05-26 Target Therapeutics, Inc. Ultrasoft embolism devices and process for using
US5342348A (en) * 1992-12-04 1994-08-30 Kaplan Aaron V Method and device for treating and enlarging body lumens
US5443454A (en) * 1992-12-09 1995-08-22 Terumo Kabushiki Kaisha Catheter for embolectomy
US5423849A (en) * 1993-01-15 1995-06-13 Target Therapeutics, Inc. Vasoocclusion device containing radiopaque fibers
US5462523A (en) * 1993-05-18 1995-10-31 Target Therapeutics, Inc. Drug delivery system
US5417708A (en) * 1994-03-09 1995-05-23 Cook Incorporated Intravascular treatment system and percutaneous release mechanism therefor
WO1995025480A1 (en) * 1994-03-18 1995-09-28 Cook Incorporated Helical embolization coil

Cited By (237)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6013084A (en) * 1995-06-30 2000-01-11 Target Therapeutics, Inc. Stretch resistant vaso-occlusive coils (II)
US6193728B1 (en) * 1995-06-30 2001-02-27 Target Therapeutics, Inc. Stretch resistant vaso-occlusive coils (II)
US5911717A (en) * 1997-03-17 1999-06-15 Precision Vascular Systems, Inc. Catheter deliverable thrombogenic apparatus and method
US5836966A (en) * 1997-05-22 1998-11-17 Scimed Life Systems, Inc. Variable expansion force stent
US6146403A (en) * 1997-05-22 2000-11-14 Scimed Life Systems, Inc. Variable expansion force stent
US6997945B2 (en) * 1997-05-22 2006-02-14 Boston Scientific Scimed, Inc. Variable expansion force stent
US7326225B2 (en) * 1997-12-05 2008-02-05 Micrus Endovascular Corporation Vasoocclusive device for treatment of aneurysms
US20040093022A9 (en) * 1997-12-05 2004-05-13 Kurz Daniel R. Vasoocclusive coil
US7070608B2 (en) * 1997-12-05 2006-07-04 Micrus Corporation Vasoocclusive coil
US20020016613A1 (en) * 1997-12-05 2002-02-07 Kurz Daniel R. Vasoocclusive coil
US6358228B1 (en) 1998-04-07 2002-03-19 Cook Incorporated Vasoocclusive device including asymmetrical pluralities of fibers
US6015424A (en) * 1998-04-28 2000-01-18 Microvention, Inc. Apparatus and method for vascular embolization
EP1518502A1 (en) 1998-04-28 2005-03-30 MicroVention, Inc. Apparatus and method for vascular embolization
US6375669B1 (en) 1998-04-28 2002-04-23 Microvention, Inc. Apparatus and method for vascular embolization
US6379379B1 (en) 1998-05-05 2002-04-30 Scimed Life Systems, Inc. Stent with smooth ends
US6652575B2 (en) 1998-05-05 2003-11-25 Scimed Life Systems, Inc. Stent with smooth ends
US20040098119A1 (en) * 1998-05-05 2004-05-20 Scimed Life Systems, Inc. Stent with smooth ends
US6299627B1 (en) * 1998-06-18 2001-10-09 Target Therapeutics, Inc. Water-soluble coating for bioactive vasoocclusive devices
US5980550A (en) * 1998-06-18 1999-11-09 Target Therapeutics, Inc. Water-soluble coating for bioactive vasoocclusive devices
US6500190B2 (en) 1998-07-06 2002-12-31 Microvention Vascular embolization with an expansible implant
US7799047B2 (en) 1998-07-06 2010-09-21 Microvention, Inc. Vascular embolization with an expansible implant
US7201762B2 (en) 1998-07-06 2007-04-10 Microvention, Inc. Vascular embolization with an expansible implant
US20110005062A1 (en) * 1998-07-06 2011-01-13 Greene Jr George R Vascular Embolization With An Expansible Implant
US7483558B2 (en) 1998-07-06 2009-01-27 Microvention, Inc. Vascular embolization with an expansible implant
US20030083737A1 (en) * 1998-07-06 2003-05-01 Greene George R. Vascular embolization with an expansible implant
US6165193A (en) * 1998-07-06 2000-12-26 Microvention, Inc. Vascular embolization with an expansible implant
US9034005B2 (en) 1998-07-06 2015-05-19 Microvention, Inc. Vascular embolization with an expansible implant
US7029487B2 (en) 1998-07-06 2006-04-18 Microvention, Inc. Vascular embolization with an expansible implant
US20090112250A1 (en) * 1998-07-06 2009-04-30 Greene Jr George R Vascular Embolization With An Expansible Implant
US6723112B2 (en) 1998-11-10 2004-04-20 Scimed Life Systems, Inc. Bioactive three loop coil
US6187024B1 (en) 1998-11-10 2001-02-13 Target Therapeutics, Inc. Bioactive coating for vaso-occlusive devices
US8016852B2 (en) * 1998-11-10 2011-09-13 Stryker Corporation Bioactive components for incorporation with vaso-occlusive members
US6569179B2 (en) 1998-11-10 2003-05-27 Scimed Life Systems, Inc. Bioactive three loop coil
US6231590B1 (en) 1998-11-10 2001-05-15 Scimed Life Systems, Inc. Bioactive coating for vaso-occlusive devices
US20040093014A1 (en) * 1998-11-10 2004-05-13 Hanh Ho Bioactive components for incorporation with vaso-occlusive members
US20090076540A1 (en) * 1999-06-02 2009-03-19 Marks Michael P Intracorporeal Occlusive Device And Method
US20060265001A1 (en) * 1999-06-02 2006-11-23 Marks Michael P Intracorporeal occlusive device and method
US20050267511A1 (en) * 1999-06-02 2005-12-01 Marks Michael P Intracorporeal occlusive device and method
US9788840B2 (en) 1999-06-02 2017-10-17 Michael P. Marks Intracorporeal occlusive device and method
EP1992308B1 (en) * 1999-06-02 2015-10-28 Microtransform, Inc. Intracorporeal occlusive device
US9526505B2 (en) 1999-06-02 2016-12-27 Microvention, Inc. Intracorporeal occlusive device and method
US20020099408A1 (en) * 1999-06-02 2002-07-25 Marks Michael P. Method and apparatus for detaching an intracorporeal occlusive device
EP1992308A2 (en) * 1999-06-02 2008-11-19 Microtransform, Inc. Intracorporeal occlusive device
US20060271099A1 (en) * 1999-06-02 2006-11-30 Marks Michael P Intracorporeal occlusive device and method
US8932317B2 (en) 1999-06-02 2015-01-13 Microvention, Inc. Intracorporeal occlusive device and method
EP2308393A1 (en) 1999-10-04 2011-04-13 MicroVention, Inc. Embolic device
EP2008596A1 (en) 1999-10-04 2008-12-31 MicroVention, Inc. Embolic device
US8597321B2 (en) 1999-10-30 2013-12-03 Covidien Lp Device for the implantation of occlusion spirals
US20030225309A1 (en) * 1999-12-08 2003-12-04 Clifford Teoh Radioactive compositions and methods of use thereof
US6616591B1 (en) 1999-12-08 2003-09-09 Scimed Life Systems, Inc. Radioactive compositions and methods of use thereof
US20050038460A1 (en) * 1999-12-23 2005-02-17 Swaminathan Jayaraman Occlusive coil manufacture and delivery
US6790218B2 (en) 1999-12-23 2004-09-14 Swaminathan Jayaraman Occlusive coil manufacture and delivery
US20050187564A1 (en) * 1999-12-23 2005-08-25 Swaminathan Jayaraman Occlusive coil manufacturing and delivery
US6656200B2 (en) 2000-04-07 2003-12-02 Collagen Matrix, Inc. Embolization device
US20060184195A1 (en) * 2000-09-26 2006-08-17 Microvention, Inc. Microcoil vaso-occlusive device with multi-axis secondary configuration
US8323306B2 (en) 2000-09-26 2012-12-04 Microvention, Inc. Microcoil vaso-occlusive device with multi-axis secondary configuration
US7331974B2 (en) 2000-09-26 2008-02-19 Microvention, Inc. Microcoil vaso-occlusive device with multi-axis secondary configuration
US7029486B2 (en) 2000-09-26 2006-04-18 Microvention, Inc. Microcoil vaso-occlusive device with multi-axis secondary configuration
US20040045554A1 (en) * 2000-09-26 2004-03-11 Dean Schaefer Microcoil vaso-occlusive device with multi-axis secondary configuration
US7033374B2 (en) 2000-09-26 2006-04-25 Microvention, Inc. Microcoil vaso-occlusive device with multi-axis secondary configuration
US20020107534A1 (en) * 2000-09-26 2002-08-08 Dean Schaefer Microcoil vaso-occlusive device with multi-axis secondary configuration
US6605101B1 (en) 2000-09-26 2003-08-12 Microvention, Inc. Microcoil vaso-occlusive device with multi-axis secondary configuration
US20030018356A1 (en) * 2000-09-26 2003-01-23 Dean Schaefer Microcoil vaso-occlusive device with multi-axis secondary configuration
US6689141B2 (en) 2000-10-18 2004-02-10 Microvention, Inc. Mechanism for the deployment of endovascular implants
EP1925258A2 (en) 2000-10-18 2008-05-28 MicroVention, Inc. Mechanism for the deployment of endovascular implants
US20040204701A1 (en) * 2000-10-18 2004-10-14 Brian Cox Mechanism for the deployment of endovascular implants
US8048104B2 (en) 2000-10-30 2011-11-01 Dendron Gmbh Device for the implantation of occlusion spirals
US20080051803A1 (en) * 2000-10-30 2008-02-28 Dendron Gmbh Device for the implantation of occlusion spirals
US20020082620A1 (en) * 2000-12-27 2002-06-27 Elaine Lee Bioactive materials for aneurysm repair
US6602269B2 (en) 2001-03-30 2003-08-05 Scimed Life Systems Embolic devices capable of in-situ reinforcement
EP1955665A2 (en) 2001-03-30 2008-08-13 Boston Scientific Scimed, Inc. Embolic devices capable of in-situ reinforcement
WO2002096496A1 (en) * 2001-03-30 2002-12-05 Scimed Life Systems, Inc. Embolic devices capable of in-situ reinforcement
WO2002080782A1 (en) 2001-04-06 2002-10-17 Scimed Life Systems Bioactive occlusion coil
WO2002089863A1 (en) 2001-05-04 2002-11-14 Concentric Medical Bioactive polymer vaso-occlusive device
EP2319430A2 (en) 2001-05-29 2011-05-11 Microvention, Inc. Medical device and method of manufacture
WO2003015640A1 (en) 2001-08-16 2003-02-27 Scimed Life Systems, Inc. Bioactive occlusion coil
EP2163212A1 (en) 2001-11-07 2010-03-17 Microvention, Inc. Microcoil vaso-occlusive device with multi-axis secondary configuration
EP2363081A1 (en) 2002-01-11 2011-09-07 MicroVention, Inc. Microcoil vaso-occlusive device with multi-axis secondary configuration
EP2353523A2 (en) 2002-01-11 2011-08-10 MicroVention, Inc. Microcoil vaso-occlusive device with multi-axis secondary configuration
US20030199887A1 (en) * 2002-04-23 2003-10-23 David Ferrera Filamentous embolization device and method of use
US20040006362A1 (en) * 2002-07-02 2004-01-08 Dean Schaefer Uniaxial multifilar vaso-occlusive device with high stretch resistance and low buckling strength
WO2004004581A1 (en) 2002-07-02 2004-01-15 Microvention, Inc. Uniaxial multifilar vaso-occlusive device with high stretch resistance and low buckling strength
US8882796B2 (en) 2002-07-31 2014-11-11 Microvention, Inc. Three element coaxial vaso-occlusive device
US7803395B2 (en) 2003-05-15 2010-09-28 Biomerix Corporation Reticulated elastomeric matrices, their manufacture and use in implantable devices
US8043321B2 (en) * 2003-07-24 2011-10-25 Boston Scientific Scimed, Inc. Embolic coil
US20050021074A1 (en) * 2003-07-24 2005-01-27 Elliott Christopher J. Embolic coil
US20050090856A1 (en) * 2003-10-27 2005-04-28 Scimed Life Systems, Inc. Vasco-occlusive devices with bioactive elements
US20050090861A1 (en) * 2003-10-27 2005-04-28 Scimed Life Systems, Inc. Vaso-occlusive devices with in-situ stiffening elements
US7645292B2 (en) 2003-10-27 2010-01-12 Boston Scientific Scimed, Inc. Vaso-occlusive devices with in-situ stiffening elements
US20060190076A1 (en) * 2003-11-17 2006-08-24 Taheri Syde A Temporary absorbable venous occlusive stent and superficial vein treatment method
US7294123B2 (en) * 2003-12-17 2007-11-13 Corris Neurovascular, Inc. Activatable bioactive vascular occlusive device and method of use
US20050137623A1 (en) * 2003-12-17 2005-06-23 Jones Donald K. Activatable foam expandable implantable medical device and method of use
US20050149107A1 (en) * 2003-12-17 2005-07-07 Jones Donald K. Activatable bioactive vascular occlusive device and method of use
US20070255253A1 (en) * 2003-12-17 2007-11-01 Jones Donald K Activatable bioactive vascular occlusive device and method of use
US20050137568A1 (en) * 2003-12-17 2005-06-23 Jones Donald K. Activatable bioactive implantable medical device and method of use
US7763077B2 (en) 2003-12-24 2010-07-27 Biomerix Corporation Repair of spinal annular defects and annulo-nucleoplasty regeneration
US20050155610A1 (en) * 2004-01-16 2005-07-21 Mitsuo Satake Bioabsorbable vasoocclusive coil
US8480701B2 (en) 2004-01-21 2013-07-09 Dendron Gmbh Device for implanting electrically isolated occlusion helixes
US20100076479A1 (en) * 2004-01-21 2010-03-25 Hermann Monstadt Device for implanting electrically isolated occlusion helixes
US9254134B2 (en) 2004-01-21 2016-02-09 Dendron Gmbh Device for implanting electrically isolated occlusion helixes
US20050181155A1 (en) * 2004-02-12 2005-08-18 Share Paul E. Container having barrier properties and method of manufacturing the same
US8192676B2 (en) 2004-02-12 2012-06-05 Valspar Sourcing, Inc. Container having barrier properties and method of manufacturing the same
US7247159B2 (en) 2004-04-08 2007-07-24 Cordis Neurovascular, Inc. Activatable bioactive vascular occlusive device
US7244261B2 (en) 2004-04-08 2007-07-17 Cordis Neurovascular, Inc. Activatable bioactive vascular occlusive device
US20050228435A1 (en) * 2004-04-08 2005-10-13 Lorenzo Juan A Activatable bioactive vascular occlusive device
US20050228436A1 (en) * 2004-04-08 2005-10-13 Lorenzo Juan A Activatable bioactive vascular occlusive device
US7896899B2 (en) 2004-05-21 2011-03-01 Micro Therapeutics, Inc. Metallic coils enlaced with biological or biodegradable or synthetic polymers or fibers for embolization of a body cavity
EP2316355A1 (en) 2004-05-21 2011-05-04 Micro Therapeutics, Inc. Metallic coils enlaced with biological or biodegradable or synthetic polymers or fibers for embolization of a body cavity
US8267955B2 (en) 2004-05-21 2012-09-18 Tyco Healthcare Group Lp Metallic coils enlaced with fibers for embolization of a body cavity
US20110118777A1 (en) * 2004-05-21 2011-05-19 Micro Therapeutics, Inc. Metallic coils enlaced with fibers for embolization of a body cavity
JP2008500148A (en) * 2004-05-21 2008-01-10 マイクロ セラピューティクス， インコーポレイテッド Coil made of metal to occlude a body cavity wrapped with a biological, biodegradable or synthetic polymer or fiber
US20060036281A1 (en) * 2004-05-21 2006-02-16 Micro Therapeutics, Inc. Metallic coils enlaced with biological or biodegradable or synthetic polymers or fibers for embolization of a body cavity
JP4723584B2 (en) * 2004-05-21 2011-07-13 マイクロ セラピューティクス， インコーポレイテッド Coil made of metal to occlude a body cavity wrapped with a biological, biodegradable or synthetic polymer or fiber
JP2011136189A (en) * 2004-05-21 2011-07-14 Micro Therapeutics Inc Metallic coil enlaced with biological or biodegradable or synthetic polymers or fibers for embolization of body cavity
US9198665B2 (en) 2004-09-22 2015-12-01 Covidien Lp Micro-spiral implantation device
US8372110B2 (en) 2004-09-22 2013-02-12 Covidien Lp Medical implant
US7879064B2 (en) 2004-09-22 2011-02-01 Micro Therapeutics, Inc. Medical implant
US20080103585A1 (en) * 2004-09-22 2008-05-01 Dendron Gmbh Micro-Spiral Implantation Device
US8845676B2 (en) 2004-09-22 2014-09-30 Micro Therapeutics Micro-spiral implantation device
US20080319532A1 (en) * 2004-09-22 2008-12-25 Ev3, Inc. Medical Implant
US9050095B2 (en) 2004-09-22 2015-06-09 Covidien Lp Medical implant
US20110098814A1 (en) * 2004-09-22 2011-04-28 Micro Therapeutics, Inc. Medical implant
US8771294B2 (en) 2004-11-26 2014-07-08 Biomerix Corporation Aneurysm treatment devices and methods
US8011370B2 (en) 2005-01-25 2011-09-06 Tyco Healthcare Group Lp Method for permanent occlusion of fallopian tube
US8333201B2 (en) 2005-01-25 2012-12-18 Covidien Lp Method for permanent occlusion of fallopian tube
US20060229669A1 (en) * 2005-01-25 2006-10-12 Mirizzi Michael S Method and apparatus for implanting an occlusive structure
US7972354B2 (en) 2005-01-25 2011-07-05 Tyco Healthcare Group Lp Method and apparatus for impeding migration of an implanted occlusive structure
US8262695B2 (en) 2005-01-25 2012-09-11 Tyco Healthcare Group Lp Structures for permanent occlusion of a hollow anatomical structure
US9017350B2 (en) * 2005-01-25 2015-04-28 Covidien Lp Expandable occlusive structure
US8333786B2 (en) 2005-01-25 2012-12-18 Covidien Lp Method and apparatus for implanting an occlusive structure
US8968353B2 (en) 2005-01-25 2015-03-03 Covidien Lp Method and apparatus for impeding migration of an implanted occlusive structure
US7815661B2 (en) 2005-01-25 2010-10-19 Tyco Healthcare Group, Lp Method and apparatus for implanting an occlusive structure
US20090254111A1 (en) * 2005-04-28 2009-10-08 Hermann Monstadt Device for implanting occlusion spirals comprising an interior securing element
US20100256669A1 (en) * 2005-12-02 2010-10-07 C.R. Bard, Inc. Helical Vena Cava Filter
US8864790B2 (en) 2006-04-17 2014-10-21 Covidien Lp System and method for mechanically positioning intravascular implants
US8795320B2 (en) 2006-04-17 2014-08-05 Covidien Lp System and method for mechanically positioning intravascular implants
US8795321B2 (en) 2006-04-17 2014-08-05 Covidien Lp System and method for mechanically positioning intravascular implants
US8777978B2 (en) 2006-04-17 2014-07-15 Covidien Lp System and method for mechanically positioning intravascular implants
US8777979B2 (en) 2006-04-17 2014-07-15 Covidien Lp System and method for mechanically positioning intravascular implants
US9017361B2 (en) 2006-04-20 2015-04-28 Covidien Lp Occlusive implant and methods for hollow anatomical structure
US20070299464A1 (en) * 2006-06-15 2007-12-27 Microvention, Inc. Embolization device constructed from expansile polymer
US20180110527A1 (en) * 2006-06-15 2018-04-26 Microvention, Inc. Embolization Device Constructed From Expansile Polymer
US9451963B2 (en) * 2006-06-15 2016-09-27 Microvention, Inc. Embolization device constructed from expansile polymer
US11160557B2 (en) 2006-06-15 2021-11-02 Microvention, Inc. Embolization device constructed from expansile polymer
US20160345978A1 (en) * 2006-06-15 2016-12-01 Microvention, Inc. Embolization Device Constructed From Expansile Polymer
US8377091B2 (en) 2006-06-15 2013-02-19 Microvention, Inc. Embolization device constructed from expansile polymer
US11185336B2 (en) 2006-06-15 2021-11-30 Microvention, Inc. Embolization device constructed from expansile polymer
US9259228B2 (en) 2006-06-15 2016-02-16 Microvention, Inc. Embolization device constructed from expansile polymer
US10499925B2 (en) * 2006-06-15 2019-12-10 Microvention, Inc. Embolization device constructed from expansile polymer
US10226258B2 (en) 2006-06-15 2019-03-12 Microvention, Inc. Embolization device constructed from expansile polymer
US9724103B2 (en) 2006-06-15 2017-08-08 Microvention, Inc. Embolization device constructed from expansile polymer
US9877731B2 (en) * 2006-06-15 2018-01-30 Microvention, Inc. Embolization device constructed from expansile polymer
EP2392365A2 (en) 2006-06-15 2011-12-07 MicroVention, Inc. Method for preparing an environmentally responsive hydrogel
US20120283769A1 (en) * 2006-06-15 2012-11-08 Cruise Gregory M Embolization Device Constructed From Expansile Polymer
EP2389960A2 (en) 2006-06-15 2011-11-30 MicroVention, Inc. Environmentally Responsive Hydrogel
US10524799B2 (en) * 2007-03-05 2020-01-07 Boston Scientific Scimed, Inc. Deploying embolic coils
US20080221554A1 (en) * 2007-03-05 2008-09-11 Boston Scientific Scimed, Inc. Deploying Embolic Coils
US9289215B2 (en) 2007-03-13 2016-03-22 Covidien Lp Implant including a coil and a stretch-resistant member
US8328860B2 (en) 2007-03-13 2012-12-11 Covidien Lp Implant including a coil and a stretch-resistant member
US8801747B2 (en) 2007-03-13 2014-08-12 Covidien Lp Implant, a mandrel, and a method of forming an implant
US9023094B2 (en) 2007-06-25 2015-05-05 Microvention, Inc. Self-expanding prosthesis
US20090125051A1 (en) * 2007-11-13 2009-05-14 Boston Scientific Scimed, Inc. Combination coil and liquid embolic for embolization
US8192480B2 (en) 2007-12-21 2012-06-05 Microvention, Inc. System and method of detecting implant detachment
US9242070B2 (en) 2007-12-21 2016-01-26 MicronVention, Inc. System and method for locating detachment zone of a detachable implant
US10299755B2 (en) 2007-12-21 2019-05-28 Microvention, Inc. System and method for locating detachment zone of a detachable implant
US10194915B2 (en) 2007-12-21 2019-02-05 Microvention, Inc. Implantation devices including hydrogel filaments
US8460332B2 (en) 2007-12-21 2013-06-11 Microvention, Inc. System and method of detecting implant detachment
US9486221B2 (en) 2007-12-21 2016-11-08 Microvision, Inc. Hydrogel filaments for biomedical uses
US20090204145A1 (en) * 2008-02-12 2009-08-13 Cook Incorporated Spiral occluding device with an occlusion sail
US8545573B2 (en) * 2008-02-12 2013-10-01 Cook Medical Technologies Llc Spiral occluding device with an occlusion sail
US9622751B2 (en) * 2008-08-06 2017-04-18 Boston Scientific Scimed, Inc. Vaso-occlusive devices with textured surfaces
EP2337506A1 (en) * 2008-08-06 2011-06-29 Boston Scientific Scimed, Inc. Vaso-occlusive devices with textured surfaces
US20100036412A1 (en) * 2008-08-06 2010-02-11 Boston Scientific Scimed,Inc. Vaso-occlusive devices with textured surfaces
US9517072B2 (en) 2008-12-19 2016-12-13 Covidien Lp Method and apparatus for storage and/or introduction of implant for hollow anatomical structure
US20100160945A1 (en) * 2008-12-19 2010-06-24 Tyco Healthcare Group, Lp Method and apparatus for storage and/or introduction of implant for hollow anatomical structure
US9545257B2 (en) 2008-12-19 2017-01-17 Covidien Lp Method and apparatus for storage and/or introduction of implant for hollow anatomical structure
US10143476B2 (en) 2008-12-19 2018-12-04 Covidien Lp Method and apparatus for storage and/or introduction of implant for hollow anatomical structure
US20100160898A1 (en) * 2008-12-19 2010-06-24 Tyco Healthcare Group, Lp Method and apparatus for storage and/or introduction of implant for hollow anatomical structure
US9114200B2 (en) 2009-09-24 2015-08-25 Microvention, Inc. Injectable hydrogel filaments for biomedical uses
US20110212178A1 (en) * 2009-09-24 2011-09-01 Microvention, Inc. Injectable Hydrogel Filaments For Biomedical Uses
US9993252B2 (en) 2009-10-26 2018-06-12 Microvention, Inc. Embolization device constructed from expansile polymer
US20110184455A1 (en) * 2009-10-26 2011-07-28 Microvention, Inc. Embolization Device Constructed From Expansile Polymer
US9561125B2 (en) 2010-04-14 2017-02-07 Microvention, Inc. Implant delivery device
US10517604B2 (en) 2010-04-14 2019-12-31 Microvention, Inc. Implant delivery device
US11357513B2 (en) 2010-04-14 2022-06-14 Microvention, Inc. Implant delivery device
US11291566B2 (en) 2010-12-13 2022-04-05 Terumo Corporation Stent
DE202011111067U1 (en) 2010-12-13 2019-02-28 Microvention, Inc. stent
US11351046B2 (en) 2010-12-13 2022-06-07 Terumo Corporation Stent
US9867725B2 (en) 2010-12-13 2018-01-16 Microvention, Inc. Stent
US10463515B2 (en) 2010-12-13 2019-11-05 Terumo Corporation Stent
WO2012082440A1 (en) 2010-12-13 2012-06-21 Microvention, Inc. Stent
DE202011111035U1 (en) 2010-12-13 2018-08-19 Microvention, Inc. STENT
US9456823B2 (en) 2011-04-18 2016-10-04 Terumo Corporation Embolic devices
US10058330B2 (en) 2011-05-11 2018-08-28 Microvention, Inc. Device for occluding a lumen
US20130131711A1 (en) * 2011-11-23 2013-05-23 Microvention, Inc. Embolic Device With Shaped Wire
US10335155B2 (en) 2011-11-30 2019-07-02 Covidien Lp Positioning and detaching implants
US9579104B2 (en) 2011-11-30 2017-02-28 Covidien Lp Positioning and detaching implants
US10893868B2 (en) 2012-01-20 2021-01-19 Covidien Lp Aneurysm treatment coils
EP4059475A1 (en) 2012-03-16 2022-09-21 Terumo Corporation Stent delivery device
US9687245B2 (en) 2012-03-23 2017-06-27 Covidien Lp Occlusive devices and methods of use
US9381278B2 (en) 2012-04-18 2016-07-05 Microvention, Inc. Embolic devices
US9326774B2 (en) 2012-08-03 2016-05-03 Covidien Lp Device for implantation of medical devices
US10772638B2 (en) 2013-03-13 2020-09-15 Cook Medical Technologies Llc Occluding device and method of manufacturing occluding devices
US9974544B2 (en) 2013-03-13 2018-05-22 Cook Medical Technologies Llc Occluding device and method of manufacturing occluding devices
US9192389B2 (en) 2013-03-13 2015-11-24 Cook Medical Technologies Llc Occluding device and method of manufacturing occluding devices
US9763667B2 (en) 2013-03-14 2017-09-19 Cook Medical Technologies Llc Embolization coil with barbed fiber
US9282970B2 (en) * 2013-09-30 2016-03-15 Covidien Lp Systems and methods for positioning and compacting a bodily implant
US20150094752A1 (en) * 2013-09-30 2015-04-02 Covidien Lp Systems and methods for positioning and compacting a bodily implant
US10045786B2 (en) * 2013-12-20 2018-08-14 Microvention, Inc. Expansile member
US20150174381A1 (en) * 2013-12-20 2015-06-25 Microvention, Inc. Expansile Member
US11426175B2 (en) 2013-12-20 2022-08-30 Microvention, Inc. Expansile member
US9636118B2 (en) 2014-02-27 2017-05-02 Incumedx, Inc. Embolic framing microcoils
US10098645B2 (en) 2014-02-27 2018-10-16 Incumedx, Inc. Embolic framing microcoils
US9980734B2 (en) 2014-02-27 2018-05-29 Incumedx, Inc. Embolic framing microcoils
US10124090B2 (en) 2014-04-03 2018-11-13 Terumo Corporation Embolic devices
US9713475B2 (en) 2014-04-18 2017-07-25 Covidien Lp Embolic medical devices
US10226533B2 (en) 2014-04-29 2019-03-12 Microvention, Inc. Polymer filaments including pharmaceutical agents and delivering same
US10092663B2 (en) 2014-04-29 2018-10-09 Terumo Corporation Polymers
US10946100B2 (en) 2014-04-29 2021-03-16 Microvention, Inc. Polymers including active agents
US9808256B2 (en) 2014-08-08 2017-11-07 Covidien Lp Electrolytic detachment elements for implant delivery systems
US10874401B2 (en) 2014-08-08 2020-12-29 Covidien Lp Electrolytic and mechanical detachment for implant delivery systems
US11839380B2 (en) 2014-08-08 2023-12-12 Covidien Lp Electrolytic and mechanical detachment for implant delivery systems
US9814466B2 (en) 2014-08-08 2017-11-14 Covidien Lp Electrolytic and mechanical detachment for implant delivery systems
EP4115854A1 (en) 2015-01-12 2023-01-11 Microvention, Inc. Stent
US9717503B2 (en) 2015-05-11 2017-08-01 Covidien Lp Electrolytic detachment for implant delivery systems
US11759547B2 (en) 2015-06-11 2023-09-19 Microvention, Inc. Polymers
US10639396B2 (en) 2015-06-11 2020-05-05 Microvention, Inc. Polymers
US10307168B2 (en) 2015-08-07 2019-06-04 Terumo Corporation Complex coil and manufacturing techniques
US10828037B2 (en) 2016-06-27 2020-11-10 Covidien Lp Electrolytic detachment with fluid electrical connection
US10828039B2 (en) 2016-06-27 2020-11-10 Covidien Lp Electrolytic detachment for implantable devices
US11051822B2 (en) 2016-06-28 2021-07-06 Covidien Lp Implant detachment with thermal activation
US20180250010A1 (en) * 2017-03-06 2018-09-06 Cook Medical Technologies Llc Filamentary occlusion assembly
US20210100557A1 (en) * 2018-08-22 2021-04-08 Covidien Lp Aneurysm treatment coils and associated systems and methods of use
US10912569B2 (en) * 2018-08-22 2021-02-09 Covidien Lp Aneurysm treatment coils and associated systems and methods of use
US10905432B2 (en) * 2018-08-22 2021-02-02 Covidien Lp Aneurysm treatment coils and associated systems and methods of use
US11793523B2 (en) 2018-08-22 2023-10-24 Covidien Lp Aneurysm treatment coils and associated systems and methods of use
US11812967B2 (en) * 2018-08-22 2023-11-14 Covidien Lp Aneurysm treatment coils and associated systems and methods of use

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JP2908363B2 (en) 1999-06-21
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