US3737251A - Peristaltic pump - Google Patents
Peristaltic pump Download PDFInfo
- Publication number
- US3737251A US3737251A US00113388A US3737251DA US3737251A US 3737251 A US3737251 A US 3737251A US 00113388 A US00113388 A US 00113388A US 3737251D A US3737251D A US 3737251DA US 3737251 A US3737251 A US 3737251A
- Authority
- US
- United States
- Prior art keywords
- rate
- rotor
- incrementing
- signal
- peristaltic pump
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1095—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0289—Apparatus for withdrawing or distributing predetermined quantities of fluid
- B01L3/0293—Apparatus for withdrawing or distributing predetermined quantities of fluid for liquids
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B43/00—Machines, pumps, or pumping installations having flexible working members
- F04B43/12—Machines, pumps, or pumping installations having flexible working members having peristaltic action
- F04B43/1253—Machines, pumps, or pumping installations having flexible working members having peristaltic action by using two or more rollers as squeezing elements, the rollers moving on an arc of a circle during squeezing
- F04B43/1292—Pumps specially adapted for several tubular flexible members
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S128/00—Surgery
- Y10S128/13—Infusion monitoring
Definitions
- ABSTRACT A peristaltic or roller pump is disclosed in which a pair of compressible tubes of unequal inside diameter are held between pumping shoes and a rotor.
- the rotor has a plurality of pins equally spaced along the periphery thereof. Each of the pins carries one roller thereon for occluding the larger tube. Alternate pins carrying a second roller for occluding the smaller tube.
- a stepping motor is employed to drive the rotor in angular increments so that a precision volume can be dispensed.
- the stepping motor is driven by pulses which initially have a greater interval therebetween than would occur during the normal operation thereof. In this way, the rotor can be driven with a small torque stepping motor.
- the ends of the tubes are rigidly held adjacent to the associated pumping shoes so that the pump will operate symmetrically with the rotor being driven in either a pick up or delivery mode.
- Peristaltic pumps which employ a rotor having rollers thereon for periodically occluding a liquid carrying compressible tube, have been used for a number of years to produce a flow of liquid. These pumps are normally operated with the rotor rotating at an accurately controlled speed. The accuracy of such a peristaltic pump increases as the time interval during which the pumping occurs is increased. This is because the constant speed motor which is used to drive the rotor has a start up time interval during which the rotor is not operating at its appropriate speed. The more accurate a peristaltic pump must be during a short pumping interval, the larger and more powerful the motor driving the rotor must be. This is necessary to exert sufficient torque at start up. The high torque motor, therefore, increases the cost of presently available accurate peristaltic pumps. During normal operation of the pump, however, the extra torque capability of the motor is never employed.
- the present invention contemplates a peristaltic pump in which a compressible tube is periodically occluded by a rotor
- the advance signal is applied by a signal generator which when actuated by a start signal provides a stream of advance signals initially having greater time intervals between individual advance signals than occurs after the signal generator has stabilized at its normal operating rate.
- a pair of compressible tubes of unequal inside diameter are held between the rotor and a pair of adjustable pumping shoes.
- the rotor has a plurality of pins equally spaced along the periphery thereof.
- Each of the pins carries one roller thereon for occluding the larger tube while alternate pins carry a second roller for occluding the smaller tube.
- the area of contact between the rollers and the tubes occupies a small arc.
- FIG. 1 is an isometric view of a peristaltic pump constructed in accordance with the teachings of this invention
- FIG. 2 is a top view of a pair of compressible tubes held between a rotor and a pair of pumping shoes;
- FIG. 3 is a sectional view taken along the lines 33 of FIG. 2 showing both the motor driving the rotor and the rollers on the rotor for occluding the pair of compressible tubes;
- FIG. 4 is a block diagram of the circuitry which drives the motor in the peristaltic pump of this invention.
- FIG. 1 we see an isometric view of the peristaltic pump of this invention. All of the components of the pump are mounted either on top of or inside of a housing 10. A rotor 11 is mounted for rotary motion on a pumping platform 12 which sits on the housing 10. A tube supporting bracket 14 has a pair of pumping shoes 16 mounted therein and held to an adjustable range of positions by a pair of leaf springs 17 and adjusting screws 18.
- Adjusting screw 18 is used to calibrate the volume picked up or dispensed. Adjustment is needed to compensate for mechanical variations in the rotor, support bracket, rollers, tubing inside diameter, outside diameter, concentricity and elasticity, fluid viscosity and temperature.
- a pair of compressible tubes 19 and 21 are mounted between the rotor 11 and the pumping shoes 16 being held in place by the tube support bracket 14.
- An end bracket 22 is mounted on the end of the tube support bracket 14 to give additional strength to hold the tube 19 in place.
- a centering groove is sometimes used with smaller diameter tubing, this aligns the tube on the shoe and holds it in position.
- the spacing of the ears 23 and 24 can be varied as a means of pretensioning the tubing 19 and 21 and setting the pick up or delivery accuracy to compensate for manufacturers tolerances on the inside and outside diameters of the tubes.
- a tube lubricant is always used in area between ears, lubricant reduces tube wear and decreases motor torque requirement.
- the inside diameter of the tube 19 is approximately 4 times as great as the inside diameter of the tube 21. It is desired to have a ratio of volumes picked up or delivered from the tubes 19 and 21 of to one.
- the rate at which fluid is moved in a peristaltic pump is generally determined by the inside diameter of the pumping tube and the rate atwhich the tube is occluded. Therefore, in accordance with this invention (see FIG. 3, in particular) the rotor 11 is provided with 24 roller bearing pins designated 26 peripherally located thereon and having equal spacing therebetween. Each of the roller bearing pins 26 carry a small roller 27 seen on the right hand side thereof in FIG. 3. Each time the rotor 11 makes one complete revolution, the tube 21 is occluded 24 times against its pumping shoe 16.
- Alternate roller bearing pins 26 are provided with large rollers 28 while those in between are provided with spacer members 29.
- the large rollers 28 have the same outside diameter as the small rollers 27 and occlude the large tube 19 against its pumping shoe 16 each time it passes adjacent thereto. Therefore, for each revolution of the rotor 11 the large tube 19 is occluded 12 times by the large rollers 28.
- the spacers 29 have smaller outside diameters than the rollers 27 and 28 and do not occlude the large tube 19 but serve merely to hold the smaller roller 27 on the roller bearing pin 26 aligned with the smaller tube 21. In this way, it is assured that with an approximately four to one ratio of inside diameter between the tubes 10 and 10 to one.
- the peristaltic pump shown in FIGS. 1 through 3 is controlled by circuitry shown in FIG. 4 in which common elements have common designations.
- the rate at which fluid is passed from the pump tubes 19 and 21 is generally determined by the inside diameters thereof and the rate at which the tubes 19 and 21 are occluded against the respective pumping shoes 16 by the rollers 28 and 27 respectively.
- the providing of twice the number of rollers 27 as 28 on the rotor 11 insures that the tube 21 will be occluded at twice the rate of the tube 19. This insures the maintenance of a proper ratio of pumping from the tubes 19 and 21.
- the movement of the rotor 11 must be accurately controlled.
- the rotor 11 was controlled by a motor having an accurate speed control.
- a stepping motor 31 is employed to control the rotor 11.
- a stepping motor will rotate a fixed angular increment for each stepping sig- 21 a ratio of fluids will be passed thereby at a rate of tic pumps the hysteresis and backlash of the motor and tubing renderbidirectional operation to be unsatisfactory in practice.
- this peristaltic pump the inclusion of the-ears" 23 and 24 on the tubes and other mounting techniques including the'end bracket 22 e'nable accurate operation of the pump in both a dispense or pick up mode.
- buttons 32 and 33 On the front panel of the housing (see FIG. 1) two sets of push buttons 32 and 33 are arranged. In order to operate the peristaltic pump to pick up a predetermined volume of fluid, one of the push buttons 32 is depressed indicating the volume to be picked up.
- a pick up switch 34 (see FIGS. 1 and 4) is employed to actuate a pick up flip-flop 36 through a pick up gate 37 and a diode 38 and transmit an initial count 39 as determined by the state of the push buttons 32.
- the pick up gate 47 also actuates a four-phase generator and direction control circuit 41 which determines the direction which the stepping motor will operate.
- the pick up flipflop 36 enables the step pulse enable gate 42 to operate a step pulse generator 43.
- the step pulse generator 43 is an oscillator which provides periodic pulses to the four-phase generator direction control circuitry for stepping the stepping motor 31 once for each pulse applied to the four-phase generator and direction control 41.
- the step pulse enable gate also energizes a power level control 44 which applies power to the stepping motor 31. Therefore, it is seen that the power to the stepping motor 31 is controlled by the power level control 44 while the direction and timing of the stepping motor 31 is controlled by the four-phase generator and direction control circuitry 41 which in turn is driven by the step pulse generator 43.
- the output of the step pulse generator 43 is also applied to a pick up count and gate 46.
- the pick up and gate'46 has been enabled by the pick up flip-flop 36 over leads 47 and 48 to pass the signal supplied thereto by the step pulse generator 43. It should be observed that a dispense count gate 49 to which the signal from the step pulse generator 43 is'also applied is presently disabled.
- the output from the pick up count gate 46 is applied by a lead 51 to the pick up counter 39 which counts the pulses applied thereto until the number initially inserted therein by the pick up push buttons is reached.
- the peristaltic pump of this invention is operatable in several modes. In one mode the peristaltic pump is controlled to dispense a fixed volume of fluid ratherthan operate for a fixed amount of time. In a second mode the peristaltic pump is operated to pick up a fixed amount of fluid rather than operate for a fixed amount" of time. It should be understood that the dispense and pick up functions are performed by operating the rotor II in opposite directions. In most present day peristalthe step pulse enable gate and the pick up count gate 46. The disabled step pulse enable gate 42 turns off the step pulse generator 43 and the power level control circuitry 44. Therefore, it is seen that through this circuitry the stepping motor 31 and therefore the rotor 1 l is operated through a fixed angular increment as determined by the push buttons 32 without regard to the time interval of operation.
- the step pulse generator 43 is designed to provide pulses initially at a slower rate than it does at its steady state value. In this way, the time interval between pulses for stepping at the beginning of pumping is longer than during normal operation so that the initial torque build up can bedone slowly thereby enabling the stepping motor 31 to be smaller that would be necessary if fast start upwere required.
- a dispense gate 54 signals the four-phase generator and directional circuitry 41 to operate in the dispense direction and also triggers the dispense flip-flop S6 to enable the step pulse enable gate 42 and the dispense count gate 49.
- the step pulse enable gate 42 operates the same circuitry in the same manner as when enabled by the pick up flip-flop 36 except that now the dispense count gate 49 passes the pulses from the step pulse generator 43 to the dispense counter 57 rather than having the pick up count gate 46 pass the pulses from the step pulse generator 43 to the pick up counter 39.
- the dispense counter 57 reaches the preset count a signal appearing on the lead 58 resets the dispense flip-flop 56.
- the four-phase generator and direction control circuitry 41 drives the stepping motor 31 in the dispense direction which is opposite to the pick up direction.
- the add mode This mode is employed to extend the preselect pumping range of the pump. In this mode, the pulse generator 43 will continue to operate until the total of the numbers set by both sets of the push buttons 32 and 33 have been achieved. This mode is actuated by depressing the add button 61 which passes a signal through the add and gate 62 so long as the push button lockout or gate 59 is not actuated.
- the add and gate 62 operates both the pick up flip-flop 36 and the dispense flip-flop 56.
- the dispense flip-flop 56 is operated through a diode 63 while the pick up flipflop 36 is operated through a diode 64.
- the diode 63 is connected directly to the input of the dispense flip-flop 56 and therefrom to the four-phase direction control circuitry 41.
- the dispense count gate 49 is disabled by the pick up flip-flop 36 over a lead 66. Therefore, the pick up counter 39 is counted down until a pulse is provided thereby to reset the pick up flip-flop 36.
- the resetting of the pick up flip-flop 36 removes the signal from the lead 66 disabling the dispense count gate 49.
- the signal from the dispense flip-flop 56 enables the dispense count gate 49 until the dispense counter 57 provides a pulse on the output lead 58 thereof disabling the dispense flip-flop 56.
- the peristaltic pump will operate until the step pulse generator 43 provides a number of pulses equal to the sum of the initial counts stored in a pick up counter 39 and the dispense counter 57.
- the peristaltic pump additionally has a dispense repeat cycle in which an oscillator designated dispense repeat cycle oscillator 67 periodically sets the dispense flip-flop to operate as described above and lock out the push buttons 34, 53 and 61.
- the frequency of the dispense repeat cycle oscillator 67 is controlled by a control know 67a (see FIG. 1).
- the oscillator 67 controls the period of time between successive actuations of the dispense flip-flop 56.
- the dispense control buttons 33 control the amount of fluid dispensed during each pumping interval. In this way, the peristaltic pump can be run on what appears to be a continuous basis.
- a peristaltic pump including:
- a rotor having a peripheral edge mounted for rotation on said housing
- said peristaltic pump characterized by
- said incrementing signal generating means normally generates said incrementing signal at a first rate and initially generates said incrementing signal at a second rate, said second rate being lower than said first rate.
- the peristaltic pump as defined in claim 1 further characterized by:
- said incrementing signal generating means varying said generation of said incrementing signal from said second rate to said first rate.
- the peristaltic pump as defined in claim 2 further characterized by:
- a peristaltic pump including:
- a rotor having a peripheral edge mounted for rotation on said housing
- first means enabled by said first start signal; settable to a first preset count, for counting said incrementing signal to disable said incrementing signal generating means.
- the peristaltic pump as defined in claim 4 further characterized by:
- said incrementing signal generating means normally generates said incrementing signal at a first rate and initially generates said incrementing signal at a second rate, said second rate being lower than said first rate.
- the peristaltic pump as defined in claim 4 further characterized by:
- the peristaltic pump as defined in claim 6 further characterized by:
- the peristaltic pump as defined in claim 7 further characterized by:
- the peristaltic pump as defined in claim 8 further characterized by:
- said incrementing signal generating means normally generates said incrementing signal at a first rate and initially generates said incrementing signal at a second rate, said second rate being lower than said first rate.
- said incrementing signal generating means varying said generation of said incrementing signal from said second rate to said first rate.
- a rotor having a peripheral edge mounted for rotation on said housing
- first and second adjustable pumping shoes mounted on said housing
- first and second compressible tubes mounted between said first and second adjustable pumping shoes respectively and said roller bearing pins;
- said first compressible tube having a first inside diameter and said second compressible tube having a second inside diameter smaller than said first inside diameter;
- said second plurality of rollers are arranged on alternate ones of said plurality of roller bearing pins;
- incrementing signal generating means responsive to a start signal for repeatedly generating incrementing signal; said incrementing signal generating means normally generates said incrementing signal at a first rate and initially generates said incrementing signal at a second rate, said second rate being lower than said first rate.
Abstract
A peristaltic or roller pump is disclosed in which a pair of compressible tubes of unequal inside diameter are held between pumping shoes and a rotor. The rotor has a plurality of pins equally spaced along the periphery thereof. Each of the pins carries one roller thereon for occluding the larger tube. Alternate pins carrying a second roller for occluding the smaller tube. A stepping motor is employed to drive the rotor in angular increments so that a precision volume can be dispensed. The stepping motor is driven by pulses which initially have a greater interval therebetween than would occur during the normal operation thereof. In this way, the rotor can be driven with a small torque stepping motor. The ends of the tubes are rigidly held adjacent to the associated pumping shoes so that the pump will operate symmetrically with the rotor being driven in either a pick up or delivery mode.
Description
United States Patent [191 Berman et al.
[ 51 June 5, 1973 [54] PERISTALTIC PUMP [75] Inventors: Richard M. Berman, Dresher, Pa.;
Bernard Schwartz, Springfield; Lyman W. Bethke, Trenton, both of NJ.
[73] Assignee: Alphamedics Mtg. Corp., Levittown,
[22] Filed: Feb. 8, 1971 [21] App]. No.: 113,388
[52] US. Cl ..417/l2 [51] Int. Cl ..F04b 49/00 [58] Field of Search ..4l7/12, 45, 474-477 [56] References Cited UNITED STATES PATENTS 1,988,337 1/1935 Santiago ..4l7/477 2,434,802 l/l948 Jacobs ...417/477 3,055,551 9/1962 Johnson ..417/475 3,415,419 10/1968 .lewett et al. ..4l7/477 3,425,415 2/1969 Gordon et al. ..417/474 3,429,273 2/1969 Jones ..4l7/475 3,463,092 8/1969 Meyer ..417/477 3,597,124 8/1971 Adams ..4l7/477 Primary Examiner-William L. Freeh Att0rneyLerner, David & Littenberg 57] ABSTRACT A peristaltic or roller pump is disclosed in which a pair of compressible tubes of unequal inside diameter are held between pumping shoes and a rotor. The rotor has a plurality of pins equally spaced along the periphery thereof. Each of the pins carries one roller thereon for occluding the larger tube. Alternate pins carrying a second roller for occluding the smaller tube.
A stepping motor is employed to drive the rotor in angular increments so that a precision volume can be dispensed. The stepping motor is driven by pulses which initially have a greater interval therebetween than would occur during the normal operation thereof. In this way, the rotor can be driven with a small torque stepping motor.
The ends of the tubes are rigidly held adjacent to the associated pumping shoes so that the pump will operate symmetrically with the rotor being driven in either a pick up or delivery mode.
11 Claims, 4 Drawing Figures PERISTALTIC PUMP FIELD OF THE INVENTION This invention relates to precision pumps and particularly to precision peristaltic pumps.
BACKGROUND OF THE INVENTION Peristaltic pumps, which employ a rotor having rollers thereon for periodically occluding a liquid carrying compressible tube, have been used for a number of years to produce a flow of liquid. These pumps are normally operated with the rotor rotating at an accurately controlled speed. The accuracy of such a peristaltic pump increases as the time interval during which the pumping occurs is increased. This is because the constant speed motor which is used to drive the rotor has a start up time interval during which the rotor is not operating at its appropriate speed. The more accurate a peristaltic pump must be during a short pumping interval, the larger and more powerful the motor driving the rotor must be. This is necessary to exert sufficient torque at start up. The high torque motor, therefore, increases the cost of presently available accurate peristaltic pumps. During normal operation of the pump, however, the extra torque capability of the motor is never employed.
An additional problem encountered in present day peristaltic pumps is the backlash which is encountered when trying to reverse the direction of the pump. Most present day pumps will not run accurately in both directions.
Another additional problem encountered in present day peristaltic pumps relates to the relatively long circumferential are through which the pumping occurs, this introduces nonuniform stretching of the compressible tubing, large areas of wear, and significant fluid turbulence, also nonreversibility.
Often times it is desirable to pump two fluids having a volume ratio of ten to one. In the past two compressible tubes have been used for such a requirement. The two tubes would have different inside diameters in order to provide the two rates of delivery. It has been found, however, that when an order of magnitude difference in pumping is desired, the ratio of diameters becomes too great.
Therefore, it is an object of this invention to provide an improved peristaltic pump.
It is a further object of this invention to provide a peristaltic pump which will be accurate at start up.
It is still a further object of this invention to provide a peristaltic pump which does not require a high torque motor to overcome start up inaccuracies.
It is yet another object of this invention to provide a peristaltic pump which will accurately dispense, hold, or pick up fluid. The accuracy can be adjusted before or during operation.
It is still another object of this invention to provide a peristaltic pump in which pumping ratios of ten to one can be achieved accurately with two compressible tubes.
It is a further object of this invention to provide a peristaltic pump having a small contact arc.
BRIEF DESCRIPTION OF THE INVENTION With these and other objects in view the present invention contemplates a peristaltic pump in which a compressible tube is periodically occluded by a rotor,
having rollers thereon, against a pumping shoe in which the rotor is driven by a motor which turns a predetermined angular amount in response to an advance signal applied thereto.
The advance signal is applied by a signal generator which when actuated by a start signal provides a stream of advance signals initially having greater time intervals between individual advance signals than occurs after the signal generator has stabilized at its normal operating rate.
In one embodiment of the invention a pair of compressible tubes of unequal inside diameter are held between the rotor and a pair of adjustable pumping shoes.
The rotor has a plurality of pins equally spaced along the periphery thereof. Each of the pins carries one roller thereon for occluding the larger tube while alternate pins carry a second roller for occluding the smaller tube. The area of contact between the rollers and the tubes occupies a small arc.
DESCRIPTION OF THE DRAWINGS A more complete understanding of the invention can be had be referring to the following drawings and detailed description of the invention in which:
FIG. 1 is an isometric view of a peristaltic pump constructed in accordance with the teachings of this invention;
FIG. 2 is a top view of a pair of compressible tubes held between a rotor and a pair of pumping shoes;
FIG. 3 is a sectional view taken along the lines 33 of FIG. 2 showing both the motor driving the rotor and the rollers on the rotor for occluding the pair of compressible tubes; and
FIG. 4 is a block diagram of the circuitry which drives the motor in the peristaltic pump of this invention.
DETAILED DESCRIPTION OF THIS INVENTION Referring now to FIG. 1, we see an isometric view of the peristaltic pump of this invention. All of the components of the pump are mounted either on top of or inside of a housing 10. A rotor 11 is mounted for rotary motion on a pumping platform 12 which sits on the housing 10. A tube supporting bracket 14 has a pair of pumping shoes 16 mounted therein and held to an adjustable range of positions by a pair of leaf springs 17 and adjusting screws 18.
Adjusting screw 18 is used to calibrate the volume picked up or dispensed. Adjustment is needed to compensate for mechanical variations in the rotor, support bracket, rollers, tubing inside diameter, outside diameter, concentricity and elasticity, fluid viscosity and temperature.
A pair of compressible tubes 19 and 21 are mounted between the rotor 11 and the pumping shoes 16 being held in place by the tube support bracket 14. An end bracket 22 is mounted on the end of the tube support bracket 14 to give additional strength to hold the tube 19 in place. A centering groove is sometimes used with smaller diameter tubing, this aligns the tube on the shoe and holds it in position.
The tubes 19 and 21, before being mounted in the tube support'bracket 14, have ears 23 and 24 (see FIG. 2) molded thereon for holding the tube 19. The spacing of the ears 23 and 24 can be varied as a means of pretensioning the tubing 19 and 21 and setting the pick up or delivery accuracy to compensate for manufacturers tolerances on the inside and outside diameters of the tubes.
A tube lubricant is always used in area between ears, lubricant reduces tube wear and decreases motor torque requirement.
In this embodiment, the inside diameter of the tube 19 is approximately 4 times as great as the inside diameter of the tube 21. It is desired to have a ratio of volumes picked up or delivered from the tubes 19 and 21 of to one. The rate at which fluid is moved in a peristaltic pump is generally determined by the inside diameter of the pumping tube and the rate atwhich the tube is occluded. Therefore, in accordance with this invention (see FIG. 3, in particular) the rotor 11 is provided with 24 roller bearing pins designated 26 peripherally located thereon and having equal spacing therebetween. Each of the roller bearing pins 26 carry a small roller 27 seen on the right hand side thereof in FIG. 3. Each time the rotor 11 makes one complete revolution, the tube 21 is occluded 24 times against its pumping shoe 16. Alternate roller bearing pins 26 are provided with large rollers 28 while those in between are provided with spacer members 29. The large rollers 28 have the same outside diameter as the small rollers 27 and occlude the large tube 19 against its pumping shoe 16 each time it passes adjacent thereto. Therefore, for each revolution of the rotor 11 the large tube 19 is occluded 12 times by the large rollers 28. The spacers 29 have smaller outside diameters than the rollers 27 and 28 and do not occlude the large tube 19 but serve merely to hold the smaller roller 27 on the roller bearing pin 26 aligned with the smaller tube 21. In this way, it is assured that with an approximately four to one ratio of inside diameter between the tubes 10 and 10 to one.
The peristaltic pump shown in FIGS. 1 through 3 is controlled by circuitry shown in FIG. 4 in which common elements have common designations. As has been pointed out above, the rate at which fluid is passed from the pump tubes 19 and 21 is generally determined by the inside diameters thereof and the rate at which the tubes 19 and 21 are occluded against the respective pumping shoes 16 by the rollers 28 and 27 respectively. The providing of twice the number of rollers 27 as 28 on the rotor 11 insures that the tube 21 will be occluded at twice the rate of the tube 19. This insures the maintenance of a proper ratio of pumping from the tubes 19 and 21. In order to provide accurate absolute volume pumping, the movement of the rotor 11 must be accurately controlled.
In the prior art, the rotor 11 was controlled by a motor having an accurate speed control. In accordance with the present invention, a stepping motor 31 is employed to control the rotor 11. A stepping motor will rotate a fixed angular increment for each stepping sig- 21 a ratio of fluids will be passed thereby at a rate of tic pumps the hysteresis and backlash of the motor and tubing renderbidirectional operation to be unsatisfactory in practice. In this peristaltic pump the inclusion of the-ears" 23 and 24 on the tubes and other mounting techniques including the'end bracket 22 e'nable accurate operation of the pump in both a dispense or pick up mode.
On the front panel of the housing (see FIG. 1) two sets of push buttons 32 and 33 are arranged. In order to operate the peristaltic pump to pick up a predetermined volume of fluid, one of the push buttons 32 is depressed indicating the volume to be picked up. A pick up switch 34 (see FIGS. 1 and 4) is employed to actuate a pick up flip-flop 36 through a pick up gate 37 and a diode 38 and transmit an initial count 39 as determined by the state of the push buttons 32. The pick up gate 47 also actuates a four-phase generator and direction control circuit 41 which determines the direction which the stepping motor will operate. The pick up flipflop 36 enables the step pulse enable gate 42 to operate a step pulse generator 43. The step pulse generator 43 is an oscillator which provides periodic pulses to the four-phase generator direction control circuitry for stepping the stepping motor 31 once for each pulse applied to the four-phase generator and direction control 41. The step pulse enable gate also energizes a power level control 44 which applies power to the stepping motor 31. Therefore, it is seen that the power to the stepping motor 31 is controlled by the power level control 44 while the direction and timing of the stepping motor 31 is controlled by the four-phase generator and direction control circuitry 41 which in turn is driven by the step pulse generator 43.
The output of the step pulse generator 43 is also applied to a pick up count and gate 46. The pick up and gate'46 has been enabled by the pick up flip-flop 36 over leads 47 and 48 to pass the signal supplied thereto by the step pulse generator 43. It should be observed that a dispense count gate 49 to which the signal from the step pulse generator 43 is'also applied is presently disabled. The output from the pick up count gate 46 is applied by a lead 51 to the pick up counter 39 which counts the pulses applied thereto until the number initially inserted therein by the pick up push buttons is reached.
At that time a pulse is applied on an output lead 52 7 thereof which resets the pick up flip-flop 36 to disable nal applied thereto, and then hold its position when voltage remains. 1
The peristaltic pump of this invention is operatable in several modes. In one mode the peristaltic pump is controlled to dispense a fixed volume of fluid ratherthan operate for a fixed amount of time. In a second mode the peristaltic pump is operated to pick up a fixed amount of fluid rather than operate for a fixed amount" of time. It should be understood that the dispense and pick up functions are performed by operating the rotor II in opposite directions. In most present day peristalthe step pulse enable gate and the pick up count gate 46. The disabled step pulse enable gate 42 turns off the step pulse generator 43 and the power level control circuitry 44. Therefore, it is seen that through this circuitry the stepping motor 31 and therefore the rotor 1 l is operated through a fixed angular increment as determined by the push buttons 32 without regard to the time interval of operation.
In accordance with this invention to minimize the starting torque necessary for the stepping motor 31, the step pulse generator 43 is designed to provide pulses initially at a slower rate than it does at its steady state value. In this way, the time interval between pulses for stepping at the beginning of pumping is longer than during normal operation so that the initial torque build up can bedone slowly thereby enabling the stepping motor 31 to be smaller that would be necessary if fast start upwere required.
In a like manner when the dispense start button 53 is actuated, a dispense gate 54 signals the four-phase generator and directional circuitry 41 to operate in the dispense direction and also triggers the dispense flip-flop S6 to enable the step pulse enable gate 42 and the dispense count gate 49. The step pulse enable gate 42 operates the same circuitry in the same manner as when enabled by the pick up flip-flop 36 except that now the dispense count gate 49 passes the pulses from the step pulse generator 43 to the dispense counter 57 rather than having the pick up count gate 46 pass the pulses from the step pulse generator 43 to the pick up counter 39. When the dispense counter 57 reaches the preset count a signal appearing on the lead 58 resets the dispense flip-flop 56. During the counting of the dispense counter 57, the four-phase generator and direction control circuitry 41 drives the stepping motor 31 in the dispense direction which is opposite to the pick up direction.
Each time the pick up flip-flop 36 or the dispense flip-flop 56 is triggered the output therefrom is applied to a push button lockout or gate 59 which disables the pick up and gate, the dispense and gate and the add and gate 62. In this way, the controls of the peristaltic pump are rendered insensitive to manipulation during the pumping cycle.
Several additional features have been included in the peristaltic pump of this invention which are accomplished by simple additions to the circuitry. The first is the add mode. This mode is employed to extend the preselect pumping range of the pump. In this mode, the pulse generator 43 will continue to operate until the total of the numbers set by both sets of the push buttons 32 and 33 have been achieved. This mode is actuated by depressing the add button 61 which passes a signal through the add and gate 62 so long as the push button lockout or gate 59 is not actuated. The add and gate 62 operates both the pick up flip-flop 36 and the dispense flip-flop 56. The dispense flip-flop 56 is operated through a diode 63 while the pick up flipflop 36 is operated through a diode 64. In this embodiment it is desired that the add mode operate for dispensing fluid rather than picking up fluid. Therefore, the diode 63 is connected directly to the input of the dispense flip-flop 56 and therefrom to the four-phase direction control circuitry 41.
In this mode the dispense count gate 49 is disabled by the pick up flip-flop 36 over a lead 66. Therefore, the pick up counter 39 is counted down until a pulse is provided thereby to reset the pick up flip-flop 36. The resetting of the pick up flip-flop 36 removes the signal from the lead 66 disabling the dispense count gate 49. Thereafter the signal from the dispense flip-flop 56 enables the dispense count gate 49 until the dispense counter 57 provides a pulse on the output lead 58 thereof disabling the dispense flip-flop 56. In this way it is seen that the peristaltic pump will operate until the step pulse generator 43 provides a number of pulses equal to the sum of the initial counts stored in a pick up counter 39 and the dispense counter 57.
The peristaltic pump additionally has a dispense repeat cycle in which an oscillator designated dispense repeat cycle oscillator 67 periodically sets the dispense flip-flop to operate as described above and lock out the push buttons 34, 53 and 61. In this mode the frequency of the dispense repeat cycle oscillator 67 is controlled by a control know 67a (see FIG. 1). The oscillator 67 controls the period of time between successive actuations of the dispense flip-flop 56. The dispense control buttons 33 control the amount of fluid dispensed during each pumping interval. In this way, the peristaltic pump can be run on what appears to be a continuous basis.
It should be understood that the above embodiment is merely illustrative of the principles of this invention and that numerous other embodiments will become obvious to those of ordinary skill in the art.
What is claimed is:
l. A peristaltic pump including:
a housing;
a rotor having a peripheral edge mounted for rotation on said housing;
a plurality of rollers mounted on said rotor along said peripheral edge;
a pumping shoe mounted on said housing;
a compressible tube mounted between said pumping shoe and said rotor so that said rollers sequentially occlude said compressible tube against said pumping shoe;
said peristaltic pump characterized by;
a motor responsive to an incrementing signal for turning said rotor a fixed angular increment; and
means responsive to a first start signal for repeatedly generating said incrementing signal;
said incrementing signal generating means normally generates said incrementing signal at a first rate and initially generates said incrementing signal at a second rate, said second rate being lower than said first rate.
2. The peristaltic pump as defined in claim 1 further characterized by:
said incrementing signal generating means varying said generation of said incrementing signal from said second rate to said first rate.
3. The peristaltic pump as defined in claim 2 further characterized by:
means for periodically generating said first start signal.
4. A peristaltic pump including:
a housing;
a rotor having a peripheral edge mounted for rotation on said housing;
a plurality of rollers mounted on said rotor along said peripheral edge;
a pumping shoe mounted on said housing;
a compressible tube mounted between said pumping shoe and said rotor so that said rollers may sequen tially occlude said compressible tube against said pumping shoe;
said peristaltic pump characterized by:
a motor responsive to an incrementing signal for turning said rotor a fixed angular increment;
first means enabled by said first start signal; settable to a first preset count, for counting said incrementing signal to disable said incrementing signal generating means.
5. The peristaltic pump as defined in claim 4 further characterized by:
said incrementing signal generating means normally generates said incrementing signal at a first rate and initially generates said incrementing signal at a second rate, said second rate being lower than said first rate.
6. The peristaltic pump as defined in claim 4 further characterized by:
means for generating a second start signal; and
said motor is responsive to said rotor in a first direction and said incrementing signal and said second start signal to turn said rotor in a second direction. 7. The peristaltic pump as defined in claim 6 further characterized by:
second means enabled by said second start signal, settable to a second preset count, for counting said incrementing signal to disable said incrementing signal generating means. 8. The peristaltic pump as defined in claim 7 further characterized by:
means for generating a third start signal; and means responsive to said third start signal for disabling said incrementing signal generating means after the occurrence of incrementing signals equal to the sum of said first and second preset counts. 9. The peristaltic pump as defined in claim 8 further characterized by:
said incrementing signal generating means normally generates said incrementing signal at a first rate and initially generates said incrementing signal at a second rate, said second rate being lower than said first rate. 10. The peristaltic pump as defined in claim 9 further characterized by: I
said incrementing signal generating means varying said generation of said incrementing signal from said second rate to said first rate. 11. In combination: a housing;
a rotor having a peripheral edge mounted for rotation on said housing;
a plurality of roller bearing pins mounted on said rotor along said peripheral edge;
first and second adjustable pumping shoes mounted on said housing;
first and second compressible tubes mounted between said first and second adjustable pumping shoes respectively and said roller bearing pins;
a first plurality of rollers moiunted on each of said plurality roller bearing pins to occlude said first compressible tube against first pumping shoes;
a second plurality of rollers mounted on some of said plurality roller bearing pins to occlude said second compressible tube against said second pumping shoe;
said first compressible tube having a first inside diameter and said second compressible tube having a second inside diameter smaller than said first inside diameter;
said second plurality of rollers are arranged on alternate ones of said plurality of roller bearing pins; and
means responsive to a start signal for repeatedly generating incrementing signal; said incrementing signal generating means normally generates said incrementing signal at a first rate and initially generates said incrementing signal at a second rate, said second rate being lower than said first rate.
Claims (11)
1. A peristaltic pump including: a housing; a rotor having a peripheral edge mounted for rotation on said housing; a plurality of rollers mounted on said rotor along said peripheral edge; a pumping shoe mounted on said housing; a compressible tube mounted between said pumping shoe and said rotor so that said rollers sequentially occlude said compressible tube against said pumping shoe; said peristaltic pump characterized by; a motor responsive to an incrementing signal for turning said rotor a fixed angular increment; and means responsive to a first start signal for repeatedly generating said incrementing signal; said incrementing signal generating means normally generates said incrementing signal at a first rate and initially generates said incrementing signal at a second rate, said second rate being lower than said first rate.
2. The peristaltic pump as defined in claim 1 further characterized by: said incrementing signal generating means varying said generation of said incrementIng signal from said second rate to said first rate.
3. The peristaltic pump as defined in claim 2 further characterized by: means for periodically generating said first start signal.
4. A peristaltic pump including: a housing; a rotor having a peripheral edge mounted for rotation on said housing; a plurality of rollers mounted on said rotor along said peripheral edge; a pumping shoe mounted on said housing; a compressible tube mounted between said pumping shoe and said rotor so that said rollers may sequentially occlude said compressible tube against said pumping shoe; said peristaltic pump characterized by: a motor responsive to an incrementing signal for turning said rotor a fixed angular increment; first means enabled by said first start signal; settable to a first preset count, for counting said incrementing signal to disable said incrementing signal generating means.
5. The peristaltic pump as defined in claim 4 further characterized by: said incrementing signal generating means normally generates said incrementing signal at a first rate and initially generates said incrementing signal at a second rate, said second rate being lower than said first rate.
6. The peristaltic pump as defined in claim 4 further characterized by: means for generating a second start signal; and said motor is responsive to said rotor in a first direction and said incrementing signal and said second start signal to turn said rotor in a second direction.
7. The peristaltic pump as defined in claim 6 further characterized by: second means enabled by said second start signal, settable to a second preset count, for counting said incrementing signal to disable said incrementing signal generating means.
8. The peristaltic pump as defined in claim 7 further characterized by: means for generating a third start signal; and means responsive to said third start signal for disabling said incrementing signal generating means after the occurrence of incrementing signals equal to the sum of said first and second preset counts.
9. The peristaltic pump as defined in claim 8 further characterized by: said incrementing signal generating means normally generates said incrementing signal at a first rate and initially generates said incrementing signal at a second rate, said second rate being lower than said first rate.
10. The peristaltic pump as defined in claim 9 further characterized by: said incrementing signal generating means varying said generation of said incrementing signal from said second rate to said first rate.
11. In combination: a housing; a rotor having a peripheral edge mounted for rotation on said housing; a plurality of roller bearing pins mounted on said rotor along said peripheral edge; first and second adjustable pumping shoes mounted on said housing; first and second compressible tubes mounted between said first and second adjustable pumping shoes respectively and said roller bearing pins; a first plurality of rollers moiunted on each of said plurality roller bearing pins to occlude said first compressible tube against first pumping shoes; a second plurality of rollers mounted on some of said plurality roller bearing pins to occlude said second compressible tube against said second pumping shoe; said first compressible tube having a first inside diameter and said second compressible tube having a second inside diameter smaller than said first inside diameter; said second plurality of rollers are arranged on alternate ones of said plurality of roller bearing pins; and means responsive to a start signal for repeatedly generating incrementing signal; said incrementing signal generating means normally generates said incrementing signal at a first rate and initially generates said incrementing signal at a second rate, said second rate being lower than said first rate.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11338871A | 1971-02-08 | 1971-02-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
US3737251A true US3737251A (en) | 1973-06-05 |
Family
ID=22349106
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US00113388A Expired - Lifetime US3737251A (en) | 1971-02-08 | 1971-02-08 | Peristaltic pump |
Country Status (1)
Country | Link |
---|---|
US (1) | US3737251A (en) |
Cited By (74)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3877634A (en) * | 1973-05-25 | 1975-04-15 | Du Pont | Cell washing centrifuge apparatus and system |
US3915651A (en) * | 1972-09-22 | 1975-10-28 | Us Government | Direct digital control pipette |
US3918854A (en) * | 1974-06-19 | 1975-11-11 | Alphamedics Mfg Corp | Peristaltic pump |
US3958898A (en) * | 1972-03-06 | 1976-05-25 | Waters Associates, Incorporated | Pump control systems |
US3981620A (en) * | 1972-03-06 | 1976-09-21 | Waters Associates, Inc. | Pumping apparatus |
US3985133A (en) * | 1974-05-28 | 1976-10-12 | Imed Corporation | IV pump |
US3994687A (en) * | 1971-11-24 | 1976-11-30 | Eduard Engelbrecht | Peristaltic dilutor system and method |
FR2316456A1 (en) * | 1975-07-01 | 1977-01-28 | Bioengineering Research | ROTARY PUMP WITH ROLLERS TO PERFORM THE ALTERNATE PUMPING OF A FLUID AND IN PARTICULAR BLOOD IN EXTRA-BODY CIRCULATION |
FR2384134A1 (en) * | 1977-03-14 | 1978-10-13 | Extracorporeal Med Spec | FLUID PUMP |
US4176672A (en) * | 1977-01-11 | 1979-12-04 | Apparatebau Gauting Gmbh | Mixing apparatus for a first liquid component with at least one additional component |
FR2429341A1 (en) * | 1978-06-23 | 1980-01-18 | Inst Biolog Fiz | METERING APPARATUS AND SYSTEMS WITH PERISTALTIC ACTION |
US4199307A (en) * | 1977-07-05 | 1980-04-22 | Andros Incorporated | Medical infusion system |
US4217062A (en) * | 1978-02-27 | 1980-08-12 | Mile Lipovac | Paint feeding apparatus in combination with a fountain type paint roller |
US4217993A (en) * | 1977-12-02 | 1980-08-19 | Baxter Travenol Laboratories, Inc. | Flow metering apparatus for a fluid infusion system |
US4231707A (en) * | 1978-01-31 | 1980-11-04 | Pilot Man-Nen-Hitsu Kabushiki Kaisha | Fluid supplying device |
US4242051A (en) * | 1979-02-22 | 1980-12-30 | Knight Equipment Corp. | Feed control system for pumping fluids to dishwashers and the like |
US4263909A (en) * | 1978-02-03 | 1981-04-28 | Pitman-Moore, Inc. | Dispensing of fluent materials |
US4288205A (en) * | 1980-01-18 | 1981-09-08 | Pako Corporation | Variable volume peristaltic pump |
US4299218A (en) * | 1977-12-02 | 1981-11-10 | Baxter Travenol Laboratories, Inc. | Pre-programmable metering apparatus for a fluid infusion system |
US4299541A (en) * | 1977-11-29 | 1981-11-10 | Nikkiso Co., Ltd. | Infusion solution injecting pump |
EP0047130A2 (en) * | 1980-08-28 | 1982-03-10 | E.I. Du Pont De Nemours And Company | Flow analysis |
FR2490958A1 (en) * | 1980-09-27 | 1982-04-02 | Terumo Corp | METHOD AND APPARATUS FOR INTERMITTENTLY DISTRIBUTING MEDICAL SOLUTION IN MINIMAL DOSES |
US4379452A (en) * | 1977-10-18 | 1983-04-12 | Baxter Travenol Laboratories, Inc. | Prepackaged, self-contained fluid circuit module |
US4382753A (en) * | 1979-03-09 | 1983-05-10 | Avi, Inc. | Nonpulsating IV pump and disposable pump chamber |
US4391600A (en) * | 1979-03-09 | 1983-07-05 | Avi, Inc. | Nonpulsating IV pump and disposable pump chamber |
US4410322A (en) * | 1979-03-09 | 1983-10-18 | Avi, Inc. | Nonpulsating TV pump and disposable pump chamber |
US4416280A (en) * | 1980-04-07 | 1983-11-22 | Minnesota Mining And Manufacturing Company | Cardioplegia delivery system |
US4446993A (en) * | 1977-07-19 | 1984-05-08 | Pilot Man-Nen-Hitsu Kabushiki Kaisha | Apparatus for dispensing a preselected amount of liquid |
US4473173A (en) * | 1983-01-10 | 1984-09-25 | Applied Color Systems, Inc. | Apparatus and method for low volume dispensing |
US4486097A (en) | 1981-09-09 | 1984-12-04 | E. I. Du Pont De Nemours & Company, Inc. | Flow analysis |
US4537561A (en) * | 1983-02-24 | 1985-08-27 | Medical Technology, Ltd. | Peristaltic infusion pump and disposable cassette for use therewith |
US4597298A (en) * | 1982-06-04 | 1986-07-01 | Bifok Ab | Hydrodynamic sample introducing system |
EP0188288A2 (en) * | 1985-01-18 | 1986-07-23 | Ivion Corporation | Device and method for effecting application of a therapeutic agent |
US4610544A (en) * | 1981-09-09 | 1986-09-09 | Clifford Riley | Flow analysis |
US4725205A (en) * | 1987-01-30 | 1988-02-16 | Fisher Scientific Group Inc. | Peristaltic pump with cam action compensator |
US4728265A (en) * | 1987-01-30 | 1988-03-01 | Fisher Scientific Group Inc. | Peristaltic pump with cam action compensator |
US4838860A (en) * | 1987-06-26 | 1989-06-13 | Pump Controller Corporation | Infusion pump |
US4857048A (en) * | 1987-05-29 | 1989-08-15 | Hewlett-Packard Company | IV pump and disposable flow chamber with flow control |
US4856972A (en) * | 1988-06-09 | 1989-08-15 | Fisher Scientific Co. | Dual roller peristaltic pump |
US4898579A (en) * | 1987-06-26 | 1990-02-06 | Pump Controller Corporation | Infusion pump |
US4909713A (en) * | 1986-05-07 | 1990-03-20 | Cobe Laboratories, Inc. | Peristaltic pump |
US4928587A (en) * | 1988-02-26 | 1990-05-29 | Motorola Inc. | Programmable pad printer |
US5064358A (en) * | 1988-06-14 | 1991-11-12 | Alessandro Calari | Peristaltic pump adapted to operate simultaneously on two lines |
US5083908A (en) * | 1989-03-24 | 1992-01-28 | Asulab S.A. | Miniature peristaltic pump |
US5088981A (en) * | 1985-01-18 | 1992-02-18 | Howson David C | Safety enhanced device and method for effecting application of a therapeutic agent |
JPH04119376U (en) * | 1991-04-05 | 1992-10-26 | セイコー電子工業株式会社 | peristaltic pump |
US5181842A (en) * | 1990-06-15 | 1993-01-26 | Sherwood Medical Company | Peristaltic infusion device |
WO1994004257A1 (en) * | 1992-08-11 | 1994-03-03 | American Cyanamid Company | Apparatus for combining liquids |
US5320503A (en) * | 1988-05-17 | 1994-06-14 | Patient Solutions Inc. | Infusion device with disposable elements |
US5398605A (en) * | 1993-08-18 | 1995-03-21 | Tokyo Kirai Seisakusho, Ltd. | Ink pump control system |
US5441636A (en) * | 1993-02-12 | 1995-08-15 | Cobe Laboratories, Inc. | Integrated blood treatment fluid module |
US5447417A (en) * | 1993-08-31 | 1995-09-05 | Valleylab Inc. | Self-adjusting pump head and safety manifold cartridge for a peristaltic pump |
US5584667A (en) * | 1988-05-17 | 1996-12-17 | Davis; David L. | Method of providing uniform flow from an infusion device |
DE4295020C2 (en) * | 1992-09-02 | 1997-07-31 | Valerij Viktorovic Skobelev | Pump for biological fluids, e.g. blood |
US5803712A (en) * | 1988-05-17 | 1998-09-08 | Patient Solutions, Inc. | Method of measuring an occlusion in an infusion device with disposable elements |
US6039868A (en) * | 1995-02-09 | 2000-03-21 | First Medical, Inc. | Blood separator system |
EP1485617A1 (en) * | 2002-02-21 | 2004-12-15 | Terumo Cardiovascular Systems Corporation | Dynamic brake with backlash control for peristaltic pump |
US20040254527A1 (en) * | 2003-06-10 | 2004-12-16 | Vitello Christopher John | Apparatus and methods for administering bioactive compositions |
US20060002805A1 (en) * | 2004-06-30 | 2006-01-05 | Millipore Corporation | Peristaltic pump comprising members for locating a tube |
US20060031099A1 (en) * | 2003-06-10 | 2006-02-09 | Vitello Christopher J | System and methods for administering bioactive compositions |
US20070077152A1 (en) * | 2005-09-30 | 2007-04-05 | Sherwood Services Ag | Aliquot correction for feeding set degradation |
US20070088269A1 (en) * | 2005-09-30 | 2007-04-19 | Sherwood Services Ag | Medical pump with lockout system |
US20070201993A1 (en) * | 2006-02-28 | 2007-08-30 | Terentiev Alexandre N | Disposable pumping apparatus based on flexible vessels in pressurized containers |
US20080031740A1 (en) * | 2006-08-01 | 2008-02-07 | Seiko Epson Corporation | Fluid conveyance system and fluid conveyance device |
US20080119822A1 (en) * | 2006-11-17 | 2008-05-22 | Tyco Healthcare Group Lp | Enteral fluid delivery system and method for opeating the same |
US20080154184A1 (en) * | 2006-12-20 | 2008-06-26 | Blight David D | Arthroscopic irrigation/aspiration pump system with declogging feature |
US20090214366A1 (en) * | 2008-02-27 | 2009-08-27 | Smith & Nephew, Inc. | Peristaltic Pumping Apparatus and Method |
US20090312708A1 (en) * | 2005-04-27 | 2009-12-17 | Seiko Epson Corporation | Fluid transportation system and method of setting fluid ejection amount |
US20110100064A1 (en) * | 2004-12-23 | 2011-05-05 | Nextrom Holling, S. A. | Method and apparatus for manufacturing an optical fiber core rod |
US20110180172A1 (en) * | 2010-01-22 | 2011-07-28 | Blu-White Industries, Inc. | High pressure, high flow rate tubing assembly for a positive displacement pump |
US9777720B2 (en) | 2013-03-14 | 2017-10-03 | Blue-White Industries, Ltd. | High pressure, high flow rate tubing assembly and adapter for a positive displacement pump |
US9909579B2 (en) | 2014-06-09 | 2018-03-06 | Blue-White Industries, Ltd. | Overmolded tubing assembly and adapter for a positive displacement pump |
US11578716B2 (en) | 2010-01-22 | 2023-02-14 | Blue-White Industries, Ltd. | Overmolded tubing assembly and adapter for a positive displacement pump |
US11596788B2 (en) | 2016-03-02 | 2023-03-07 | Memorial Sloan-Kettering Cancer Center | System, method and computer-accessible medium for treating circulating tumor cells in the blood stream |
Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1988337A (en) * | 1933-12-21 | 1935-01-15 | Santiago Manoel Cordeiro | Pump |
US2434802A (en) * | 1945-10-01 | 1948-01-20 | Albert A Jacobs | Pump of the tube compressing type |
US3055551A (en) * | 1959-06-29 | 1962-09-25 | Philip A Johnson | Empty-sensing and pump apparatus for liquid vending machines |
US3415419A (en) * | 1966-10-27 | 1968-12-10 | Jewett | Fluid administering system |
US3425415A (en) * | 1966-05-02 | 1969-02-04 | Iit Res Inst | Controlled infusion system |
US3429273A (en) * | 1967-12-05 | 1969-02-25 | Charles B Jones Jr | Peristaltic pump |
US3463092A (en) * | 1966-08-01 | 1969-08-26 | Biotec Ab | Hose pump |
US3597124A (en) * | 1969-09-04 | 1971-08-03 | Cenco Medical Health Supply Co | Perastaltic pump |
-
1971
- 1971-02-08 US US00113388A patent/US3737251A/en not_active Expired - Lifetime
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1988337A (en) * | 1933-12-21 | 1935-01-15 | Santiago Manoel Cordeiro | Pump |
US2434802A (en) * | 1945-10-01 | 1948-01-20 | Albert A Jacobs | Pump of the tube compressing type |
US3055551A (en) * | 1959-06-29 | 1962-09-25 | Philip A Johnson | Empty-sensing and pump apparatus for liquid vending machines |
US3425415A (en) * | 1966-05-02 | 1969-02-04 | Iit Res Inst | Controlled infusion system |
US3463092A (en) * | 1966-08-01 | 1969-08-26 | Biotec Ab | Hose pump |
US3415419A (en) * | 1966-10-27 | 1968-12-10 | Jewett | Fluid administering system |
US3429273A (en) * | 1967-12-05 | 1969-02-25 | Charles B Jones Jr | Peristaltic pump |
US3597124A (en) * | 1969-09-04 | 1971-08-03 | Cenco Medical Health Supply Co | Perastaltic pump |
Cited By (100)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3994687A (en) * | 1971-11-24 | 1976-11-30 | Eduard Engelbrecht | Peristaltic dilutor system and method |
US3958898A (en) * | 1972-03-06 | 1976-05-25 | Waters Associates, Incorporated | Pump control systems |
US3981620A (en) * | 1972-03-06 | 1976-09-21 | Waters Associates, Inc. | Pumping apparatus |
US3915651A (en) * | 1972-09-22 | 1975-10-28 | Us Government | Direct digital control pipette |
US3877634A (en) * | 1973-05-25 | 1975-04-15 | Du Pont | Cell washing centrifuge apparatus and system |
US3985133A (en) * | 1974-05-28 | 1976-10-12 | Imed Corporation | IV pump |
US3918854A (en) * | 1974-06-19 | 1975-11-11 | Alphamedics Mfg Corp | Peristaltic pump |
FR2316456A1 (en) * | 1975-07-01 | 1977-01-28 | Bioengineering Research | ROTARY PUMP WITH ROLLERS TO PERFORM THE ALTERNATE PUMPING OF A FLUID AND IN PARTICULAR BLOOD IN EXTRA-BODY CIRCULATION |
US4060348A (en) * | 1975-07-01 | 1977-11-29 | Bioengineering Research S.A. | Roller pump carrying out alternate pumping operations, particularly suited to extra-corporeal blood circulation |
US4176672A (en) * | 1977-01-11 | 1979-12-04 | Apparatebau Gauting Gmbh | Mixing apparatus for a first liquid component with at least one additional component |
US4184815A (en) * | 1977-03-14 | 1980-01-22 | Extracorporeal Medical Specialties, Inc. | Roller pump rotor with integral spring arms |
FR2384134A1 (en) * | 1977-03-14 | 1978-10-13 | Extracorporeal Med Spec | FLUID PUMP |
US4199307A (en) * | 1977-07-05 | 1980-04-22 | Andros Incorporated | Medical infusion system |
US4446993A (en) * | 1977-07-19 | 1984-05-08 | Pilot Man-Nen-Hitsu Kabushiki Kaisha | Apparatus for dispensing a preselected amount of liquid |
US4379452A (en) * | 1977-10-18 | 1983-04-12 | Baxter Travenol Laboratories, Inc. | Prepackaged, self-contained fluid circuit module |
US4299541A (en) * | 1977-11-29 | 1981-11-10 | Nikkiso Co., Ltd. | Infusion solution injecting pump |
US4299218A (en) * | 1977-12-02 | 1981-11-10 | Baxter Travenol Laboratories, Inc. | Pre-programmable metering apparatus for a fluid infusion system |
US4217993A (en) * | 1977-12-02 | 1980-08-19 | Baxter Travenol Laboratories, Inc. | Flow metering apparatus for a fluid infusion system |
US4231707A (en) * | 1978-01-31 | 1980-11-04 | Pilot Man-Nen-Hitsu Kabushiki Kaisha | Fluid supplying device |
US4263909A (en) * | 1978-02-03 | 1981-04-28 | Pitman-Moore, Inc. | Dispensing of fluent materials |
US4273260A (en) * | 1978-02-03 | 1981-06-16 | Bush George E | Dispensing of fluent materials |
US4274409A (en) * | 1978-02-03 | 1981-06-23 | Bush George E | Dispensing of fluent materials |
US4217062A (en) * | 1978-02-27 | 1980-08-12 | Mile Lipovac | Paint feeding apparatus in combination with a fountain type paint roller |
FR2429341A1 (en) * | 1978-06-23 | 1980-01-18 | Inst Biolog Fiz | METERING APPARATUS AND SYSTEMS WITH PERISTALTIC ACTION |
US4242051A (en) * | 1979-02-22 | 1980-12-30 | Knight Equipment Corp. | Feed control system for pumping fluids to dishwashers and the like |
US4382753A (en) * | 1979-03-09 | 1983-05-10 | Avi, Inc. | Nonpulsating IV pump and disposable pump chamber |
US4391600A (en) * | 1979-03-09 | 1983-07-05 | Avi, Inc. | Nonpulsating IV pump and disposable pump chamber |
US4410322A (en) * | 1979-03-09 | 1983-10-18 | Avi, Inc. | Nonpulsating TV pump and disposable pump chamber |
US4288205A (en) * | 1980-01-18 | 1981-09-08 | Pako Corporation | Variable volume peristaltic pump |
US4416280A (en) * | 1980-04-07 | 1983-11-22 | Minnesota Mining And Manufacturing Company | Cardioplegia delivery system |
EP0047130A3 (en) * | 1980-08-28 | 1982-03-17 | Vickers Limited | Flow analysis |
EP0047130A2 (en) * | 1980-08-28 | 1982-03-10 | E.I. Du Pont De Nemours And Company | Flow analysis |
FR2490958A1 (en) * | 1980-09-27 | 1982-04-02 | Terumo Corp | METHOD AND APPARATUS FOR INTERMITTENTLY DISTRIBUTING MEDICAL SOLUTION IN MINIMAL DOSES |
US4610544A (en) * | 1981-09-09 | 1986-09-09 | Clifford Riley | Flow analysis |
US4486097A (en) | 1981-09-09 | 1984-12-04 | E. I. Du Pont De Nemours & Company, Inc. | Flow analysis |
US4597298A (en) * | 1982-06-04 | 1986-07-01 | Bifok Ab | Hydrodynamic sample introducing system |
US4473173A (en) * | 1983-01-10 | 1984-09-25 | Applied Color Systems, Inc. | Apparatus and method for low volume dispensing |
US4537561A (en) * | 1983-02-24 | 1985-08-27 | Medical Technology, Ltd. | Peristaltic infusion pump and disposable cassette for use therewith |
US5088981A (en) * | 1985-01-18 | 1992-02-18 | Howson David C | Safety enhanced device and method for effecting application of a therapeutic agent |
EP0188288A3 (en) * | 1985-01-18 | 1987-01-14 | Ivion Corporation | Device and method for effecting application of a therapeutic agent |
EP0188288A2 (en) * | 1985-01-18 | 1986-07-23 | Ivion Corporation | Device and method for effecting application of a therapeutic agent |
US4909713A (en) * | 1986-05-07 | 1990-03-20 | Cobe Laboratories, Inc. | Peristaltic pump |
US4725205A (en) * | 1987-01-30 | 1988-02-16 | Fisher Scientific Group Inc. | Peristaltic pump with cam action compensator |
US4728265A (en) * | 1987-01-30 | 1988-03-01 | Fisher Scientific Group Inc. | Peristaltic pump with cam action compensator |
US4857048A (en) * | 1987-05-29 | 1989-08-15 | Hewlett-Packard Company | IV pump and disposable flow chamber with flow control |
US4838860A (en) * | 1987-06-26 | 1989-06-13 | Pump Controller Corporation | Infusion pump |
US4898579A (en) * | 1987-06-26 | 1990-02-06 | Pump Controller Corporation | Infusion pump |
US4928587A (en) * | 1988-02-26 | 1990-05-29 | Motorola Inc. | Programmable pad printer |
US5584667A (en) * | 1988-05-17 | 1996-12-17 | Davis; David L. | Method of providing uniform flow from an infusion device |
US20080015506A1 (en) * | 1988-05-17 | 2008-01-17 | Davis David L | Infusion device with disposable elements |
US20050013698A1 (en) * | 1988-05-17 | 2005-01-20 | Davis David Lyle | Infusion device with disposable elements |
US6742992B2 (en) | 1988-05-17 | 2004-06-01 | I-Flow Corporation | Infusion device with disposable elements |
US5320503A (en) * | 1988-05-17 | 1994-06-14 | Patient Solutions Inc. | Infusion device with disposable elements |
US6312227B1 (en) | 1988-05-17 | 2001-11-06 | I-Flow Corp. | Infusion device with disposable elements |
US6146109A (en) * | 1988-05-17 | 2000-11-14 | Alaris Medical Systems, Inc. | Infusion device with disposable elements |
US5803712A (en) * | 1988-05-17 | 1998-09-08 | Patient Solutions, Inc. | Method of measuring an occlusion in an infusion device with disposable elements |
US4856972A (en) * | 1988-06-09 | 1989-08-15 | Fisher Scientific Co. | Dual roller peristaltic pump |
US5064358A (en) * | 1988-06-14 | 1991-11-12 | Alessandro Calari | Peristaltic pump adapted to operate simultaneously on two lines |
US5083908A (en) * | 1989-03-24 | 1992-01-28 | Asulab S.A. | Miniature peristaltic pump |
US5181842A (en) * | 1990-06-15 | 1993-01-26 | Sherwood Medical Company | Peristaltic infusion device |
JPH04119376U (en) * | 1991-04-05 | 1992-10-26 | セイコー電子工業株式会社 | peristaltic pump |
JP2597628Y2 (en) | 1991-04-05 | 1999-07-12 | セイコーインスツルメンツ株式会社 | Peristaltic pump |
WO1994004257A1 (en) * | 1992-08-11 | 1994-03-03 | American Cyanamid Company | Apparatus for combining liquids |
DE4295020C2 (en) * | 1992-09-02 | 1997-07-31 | Valerij Viktorovic Skobelev | Pump for biological fluids, e.g. blood |
US5441636A (en) * | 1993-02-12 | 1995-08-15 | Cobe Laboratories, Inc. | Integrated blood treatment fluid module |
US5398605A (en) * | 1993-08-18 | 1995-03-21 | Tokyo Kirai Seisakusho, Ltd. | Ink pump control system |
US5447417A (en) * | 1993-08-31 | 1995-09-05 | Valleylab Inc. | Self-adjusting pump head and safety manifold cartridge for a peristaltic pump |
US6039868A (en) * | 1995-02-09 | 2000-03-21 | First Medical, Inc. | Blood separator system |
EP1485617A1 (en) * | 2002-02-21 | 2004-12-15 | Terumo Cardiovascular Systems Corporation | Dynamic brake with backlash control for peristaltic pump |
EP1485617A4 (en) * | 2002-02-21 | 2006-03-08 | Terumo Cardiovascular Sys | Dynamic brake with backlash control for peristaltic pump |
US20040254527A1 (en) * | 2003-06-10 | 2004-12-16 | Vitello Christopher John | Apparatus and methods for administering bioactive compositions |
US20060031099A1 (en) * | 2003-06-10 | 2006-02-09 | Vitello Christopher J | System and methods for administering bioactive compositions |
US7819847B2 (en) | 2003-06-10 | 2010-10-26 | Hewlett-Packard Development Company, L.P. | System and methods for administering bioactive compositions |
US7442180B2 (en) | 2003-06-10 | 2008-10-28 | Hewlett-Packard Development Company, L.P. | Apparatus and methods for administering bioactive compositions |
US20060002805A1 (en) * | 2004-06-30 | 2006-01-05 | Millipore Corporation | Peristaltic pump comprising members for locating a tube |
US7467932B2 (en) * | 2004-06-30 | 2008-12-23 | Millipore Corporation | Peristaltic pump comprising members for locating a tube |
US20110100064A1 (en) * | 2004-12-23 | 2011-05-05 | Nextrom Holling, S. A. | Method and apparatus for manufacturing an optical fiber core rod |
US8251954B2 (en) | 2005-04-27 | 2012-08-28 | Seiko Epson Corporation | Fluid transportation system and method of setting fluid ejection amount |
US20090312708A1 (en) * | 2005-04-27 | 2009-12-17 | Seiko Epson Corporation | Fluid transportation system and method of setting fluid ejection amount |
US7534099B2 (en) | 2005-09-30 | 2009-05-19 | Covidien Ag | Aliquot correction for feeding set degradation |
US20070077152A1 (en) * | 2005-09-30 | 2007-04-05 | Sherwood Services Ag | Aliquot correction for feeding set degradation |
US20090191066A1 (en) * | 2005-09-30 | 2009-07-30 | Covidien Ag | Aliquot correction for feeding set degradation |
US8360757B2 (en) | 2005-09-30 | 2013-01-29 | Covidien Ag | Aliquot correction for feeding set degradation |
US20070088269A1 (en) * | 2005-09-30 | 2007-04-19 | Sherwood Services Ag | Medical pump with lockout system |
US20070201993A1 (en) * | 2006-02-28 | 2007-08-30 | Terentiev Alexandre N | Disposable pumping apparatus based on flexible vessels in pressurized containers |
US20080031740A1 (en) * | 2006-08-01 | 2008-02-07 | Seiko Epson Corporation | Fluid conveyance system and fluid conveyance device |
US7762788B2 (en) | 2006-08-01 | 2010-07-27 | Seiko Epson Corporation | Fluid conveyance system and fluid conveyance device |
US20080119822A1 (en) * | 2006-11-17 | 2008-05-22 | Tyco Healthcare Group Lp | Enteral fluid delivery system and method for opeating the same |
US20080154184A1 (en) * | 2006-12-20 | 2008-06-26 | Blight David D | Arthroscopic irrigation/aspiration pump system with declogging feature |
US8876489B2 (en) | 2008-02-27 | 2014-11-04 | Cemal Shener | Peristaltic pumping apparatus and method |
US8087909B2 (en) | 2008-02-27 | 2012-01-03 | Smith & Nephew, Inc. | Peristaltic pump and method of supplying fluid to a surgical area therewith |
US20090214366A1 (en) * | 2008-02-27 | 2009-08-27 | Smith & Nephew, Inc. | Peristaltic Pumping Apparatus and Method |
US20110180172A1 (en) * | 2010-01-22 | 2011-07-28 | Blu-White Industries, Inc. | High pressure, high flow rate tubing assembly for a positive displacement pump |
US9828984B2 (en) | 2010-01-22 | 2017-11-28 | Blue-White Industries, Ltd. | High pressure, high flow rate peristaltic pump and tubing assembly |
US11131300B2 (en) | 2010-01-22 | 2021-09-28 | Blue-White Industries, Ltd. | Overmolded tubing assembly and adapter for a positive displacement pump |
US11578716B2 (en) | 2010-01-22 | 2023-02-14 | Blue-White Industries, Ltd. | Overmolded tubing assembly and adapter for a positive displacement pump |
US11898546B2 (en) | 2010-01-22 | 2024-02-13 | Blue-White Industries, Ltd. | Overmolded tubing assembly and adapter for a positive displacement pump |
US9777720B2 (en) | 2013-03-14 | 2017-10-03 | Blue-White Industries, Ltd. | High pressure, high flow rate tubing assembly and adapter for a positive displacement pump |
US9909579B2 (en) | 2014-06-09 | 2018-03-06 | Blue-White Industries, Ltd. | Overmolded tubing assembly and adapter for a positive displacement pump |
US11596788B2 (en) | 2016-03-02 | 2023-03-07 | Memorial Sloan-Kettering Cancer Center | System, method and computer-accessible medium for treating circulating tumor cells in the blood stream |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US3737251A (en) | Peristaltic pump | |
US4255088A (en) | Liquid pumping system having means for detecting gas in the pump | |
US3798982A (en) | Pump actuator including rotatable cams | |
US4595495A (en) | Programmable solvent delivery system and process | |
US6064797A (en) | Volumetric flow equalizing drive control wheel | |
US6193480B1 (en) | System and method for increased flow uniformity | |
US4396385A (en) | Flow metering apparatus for a fluid infusion system | |
US4037598A (en) | Method and apparatus for fluid flow control | |
US4346705A (en) | Metering apparatus having rate compensation circuit | |
US4833384A (en) | Syringe drive assembly | |
US4662872A (en) | Insulin administrating apparatus | |
US4893991A (en) | Method and means for improving efficiency of peristaltic pumps | |
US5098261A (en) | Peristaltic pump and method for adjustable flow regulation | |
GB2260966A (en) | "infusion device" | |
EP0127346B1 (en) | Peristaltic pumps | |
EP0294858A3 (en) | System and device for having desired liquid volumes supplied by a metering pump in variable flow rate condition | |
JPS62126347A (en) | Liquid chromatograph | |
US4643649A (en) | Digital control for rapid refill of a liquid chromatograph pump | |
US4880149A (en) | Liquid metering device | |
JPH062650A (en) | Measuring pumping device | |
US3173575A (en) | Method and apparatus for measuring liquids | |
US2898859A (en) | Flexible tube fluid measuring and controlling device | |
EP0250095A2 (en) | Improvements in or relating to liquid dispensers | |
JPH01249967A (en) | Running controller for quantitative pump | |
US4450574A (en) | Control circuit for liquid chromatograph |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AS | Assignment |
Owner name: WARNER-LAMBERT COMPANY, A CORP. OF DE, NEW JERSEY Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:ALPHAMEDICS MFG. CORP.;REEL/FRAME:004925/0692 Effective date: 19760630 Owner name: WARNER-LAMBERT COMPANY, 201 TABOR ROAD, MORRIS PLA Free format text: ASSIGNMENT OF ASSIGNORS INTEREST.;ASSIGNOR:ALPHAMEDICS MFG. CORP.;REEL/FRAME:004925/0692 Effective date: 19760630 |