US3683926A - Tube for connecting blood vessels - Google Patents
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- US3683926A US3683926A US53454A US3683926DA US3683926A US 3683926 A US3683926 A US 3683926A US 53454 A US53454 A US 53454A US 3683926D A US3683926D A US 3683926DA US 3683926 A US3683926 A US 3683926A
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Links
- 210000004204 blood vessel Anatomy 0.000 title abstract description 21
- 239000000203 mixture Substances 0.000 claims abstract description 16
- 230000023555 blood coagulation Effects 0.000 claims description 6
- 239000003130 blood coagulation factor inhibitor Substances 0.000 claims description 6
- 239000004599 antimicrobial Substances 0.000 claims description 4
- 229920002683 Glycosaminoglycan Polymers 0.000 claims description 3
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 claims description 3
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- 229960002897 heparin Drugs 0.000 claims description 3
- 229930006000 Sucrose Natural products 0.000 abstract description 8
- 239000003112 inhibitor Substances 0.000 abstract description 8
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- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 abstract description 7
- 239000008280 blood Substances 0.000 abstract description 7
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- 239000000463 material Substances 0.000 description 9
- 238000000034 method Methods 0.000 description 9
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- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 3
- 239000004375 Dextrin Substances 0.000 description 3
- 229920001353 Dextrin Polymers 0.000 description 3
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 3
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 3
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- OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 description 2
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 2
- 229920002307 Dextran Polymers 0.000 description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 2
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- 239000004698 Polyethylene Substances 0.000 description 2
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- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 2
- GUBGYTABKSRVRQ-QUYVBRFLSA-N beta-maltose Chemical compound OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O GUBGYTABKSRVRQ-QUYVBRFLSA-N 0.000 description 2
- 230000002490 cerebral effect Effects 0.000 description 2
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- IIEDMRRXMKUOQQ-UHFFFAOYSA-N 2-(cyanomethylidene)butanoic acid Chemical compound CCC(C(O)=O)=CC#N IIEDMRRXMKUOQQ-UHFFFAOYSA-N 0.000 description 1
- 101100422780 Caenorhabditis elegans sur-5 gene Proteins 0.000 description 1
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- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 241000282414 Homo sapiens Species 0.000 description 1
- OYHQOLUKZRVURQ-HZJYTTRNSA-N Linoleic acid Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(O)=O OYHQOLUKZRVURQ-HZJYTTRNSA-N 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
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- 210000005013 brain tissue Anatomy 0.000 description 1
- 210000001168 carotid artery common Anatomy 0.000 description 1
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- 238000010438 heat treatment Methods 0.000 description 1
- 239000011796 hollow space material Substances 0.000 description 1
- 230000008069 intimal proliferation Effects 0.000 description 1
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- OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 description 1
- 235000020778 linoleic acid Nutrition 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000178 monomer Substances 0.000 description 1
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- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
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- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
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Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/11—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/11—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis
- A61B2017/1107—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis for blood vessels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/11—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis
- A61B2017/1135—End-to-side connections, e.g. T- or Y-connections
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/11—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis
- A61B2017/1139—Side-to-side connections, e.g. shunt or X-connections
Definitions
- FIGIQ FIGIA FIGZD INVENTOR JIRO SU di fl BY Wmf, zfldgPwa ATTORNEYS TUBE FOR CONNECTING BLOOD VESSELS The present invention relates to a tube for connecting blood vessels. It also relates to a method for preparation of such tube. It further relates to a method for connecting blood vessels by the aid of such tube.
- nonsuture vascular anastomosis In order to apply even to deeply located blood vessels as cerebral ones, attempts have been made on nonsuture vascular anastomosis utilizing plastic adhesives, which is easy to manipulate and less time consuming and does not need any large supplementary instruments.
- a support material shaped in, for instance, tube or rod is inserted to the lumens of both vascular ends, a plastic ad hesive is applied to this anastomotic portion and blood flow is re-established so that, after a while, the support material dissolves into blood.
- the support material should meet at least the following three requirements: (I) exerting no materialtoxicity on living bodies such as animals and human beings; (2) having such rigidity as can be readily inserted into vascular lumens; and (3 being soluble with ease into blood so as to recover smooth flow of blood as early as possible.
- a basic object of the present invention is to embody a tube useful as the support on non-suture vascular anastomosis. Another object of this invention is to embody a method for preparation of such tube. A further object of the invention is to embody a method for connecting vascular vessels by the aid of such tube. A still further object of the invention is to embody a composition suitable for preparation of such tube.
- FIG. 1 shows the front views of the tubes which are three typical embodiments of the invention. That is,
- FIG. 1 (A) shows a cylindrical tube
- FIG. 1 (B) shows a T-letter shaped tube
- FIG. 1 (C) shows a Y-letter shaped tube.
- FIG. 2 illustrates the steps for connecting blood ves sels according to the present invention.
- FIGS. 2 (A) and (B) show, respectively, two blood vessels to be connected each other at the section surface and a spindle tube (same as shown in FIG. 1 (A) to be used as the connection between the blood vessels.
- FIG. 2 (C) shows the intermediate state for connection wherein both ends of the tube, are inserted into the lumens of the blood vessels.
- FIG. 2 (D) shows perfection of the insertion wherein two ring clips are placed on the outer surfaces of the blood vessels.
- FIG. 2 (E) shows the state after accomplishment of the connection where the tube dissolved and disappears into blood flow.
- the tube of the present invention is made of a composition comprising sucrose as the main component, a crystallization inhibitor therefor and an elasticizer.
- crystallization inhibitor there are exemplified glucose, lactose, maltose, etc.
- elasticizer examples of the elasticizer are dextran, dextrin, etc.
- the weight ratio of the components affects the solubility in blood flow and the mechanical strength of the resulting tube and may be varied with the place to which the tube is applied.
- the composition includes to percent 90by weight of sucrose, 6 to 25 percent by weight of the crystallization inhibitor and 2 to 10 percent by weight of the elasticizer on the basis of the weight of the composition.
- the composition may include an antimicrobial agent, a blood coagulation inhibitor (e.g., mucopolysaccharides, heparin) and any other additive.
- a blood coagulation inhibitor e.g., mucopolysaccharides, heparin
- the said essential components with or without the said optional components are first dissolved into water.
- the resultant solution is heated up to to C. l-Ieating above 170 C is not favorable, because caramelization is caused and the caramelized product is not suitably used for the object of the invention.
- the heated solution is then cooled to about 60 C for obtaining a soft, glassy material, from which a long pipe is drawn in the same manner as adopted on the manufacture of a glass pipe.
- the pipe is then cut at a proper length to make numerous pieces of tubes, each of which is then preferably tapered at both ends so as to be easily inserted to vascular ends and also favorably provided with grooves or protuberances circumferentially on the outer surface for preventing from slipping out of vascular ends.
- the soft, glassy material may be shaped directily into a tube by the use of a mold.
- the tapering and/or the formation of grooves or protuberances may be accomplished simultaneously.
- the thus obtained tube is of hard, glassy quality and usually stored under the condition prevented from moisture.
- the tube Prior to storage or use, the tube may be dipped in a solution of the antimicrobial agent and/or the blood coagulation inhibitor and then dried to make a film of such agents on the surface.
- a solution of 80 g of sucrose, 16 g of glucose and 4 g of dextrin in 200 g of water is gradually heated up to 160 C and then allowed to stand for cooling. After cooled to 80 C, the solution is kept in a warming room and gradually cooled to about 70 C. After removal of a hard film formed on the surface, an appropriate amount of the resultant soft, glassy material is attached uniformly around a cylindrical stick made of polytetrafluoroethylene (Teflon) or glass (linoleic acid being applied previously on the surface in the latter case) so as to make a layer of 6 mm in thickness.
- Teflon polytetrafluoroethylene
- the stick When cooled to about 60 C, the stick is taken off, and the resultant hollow material is drawn to the directions of both ends while heating the central or trunk portion of the said material so as to make a pipe of l to mm in outer diameter.
- the pipe is cut by alcoholic vapor without affording any change on the inner diameter into some pieces of tubes, each tube being 10 to mm in length.
- a heated silver or platinum wire is contacted on the surface of the tube, and the tube is gradually rotated so that a groove is formed curcumferentially on the surface.
- another groove is provided on the surface at a distance from and parallel to the saidgroove.
- the grooved tube is irradiated under ultraviolet sterilization lamp and stored in a desiccator.
- the tube is readily soluble in water, sparingly soluble in anhydrous ethanol and materially insoluble in benzene, toluene, ether, fats and oils.
- EXPERIMENT l The tube of the invention was inserted to each one end of two vinyl tubes to be connected each other and, after applying an adhesive to the section surface of the vinyl tubes, they were brought into contact each other by the section surface. Then, stored blood at 37 C was flowed to the connected vinyl tube at a pressure of 130 mmI-ig. The tube of the invention dissolved completely within 40 seconds.
- EXAPERIMENT 2 Common carotid arteries, femoral arteries and femoral veins of 2.0 to 4.0 mm in external diameter from 23 mongrel dogs'weighing 4 to 11 kg were subjected to the experiment.
- the distal clamp was released first and, after confirmation of no occurrence of major bleeding, the proximal clamp was released. It was microscopically observed that anastomotic sites were covered smoothly by intimal proliferation within two weeks, and anastomosis was successfully accomplished.
- FIG. 1 shows the front views of the tubes which are three typical embodiments of the invention. That is, FIG. 1 (A) shows a cylindrical tube (1) tapered at both ends and provided two grooves (11,11) circumferentially on the outer surface. FIG. 1 (B) shows a T-letter shaped tube (2) tapered at each end and provided three pairs of protuberances (21,21,21) circumferentially on the outer surface. FIG. 1
- - l (C) shows a Y-letter shaped tube (3) tapered at each end and provided three grooves (31,31,31) circumferentially on the outer surface.
- the tapered portion is served for making it easy to insert into vascular lumens.
- the grooves and the protuberances are available for prevention of slipping out of vascular ends. If desired, ring clips may be placed on the groove or protuberance portion after insertion the tube in blood vessels.
- FIG. 2 illustrates the steps for connecting blood vessels according to the present invention.
- FIGS. 2 (A) and (B) show respectively two blood vessels (4,4) to be connected each other at the section surface (41) and a spindle tube (5) (same as shown in FIG. 1 (A)) provided two grooves (51,51) before the connection.
- FIG. 2 (C) showing the intermediate state for connection, both ends of the tube (5) are inserted into the lumens of the blood vessels (4,4).
- an adhesive is applied to the section surface (41).
- FIG. 2 (D) showing perfection of the insertion, two ring clips (6,6) are placed on the outer surfaces of the blood vessels at the places corresponding to the grooves of the tube now completely enclosed in the blood vessels for securing the connecting.
- FIG. 2 (E) there is shown the state after accomplishment of the connection where the tube dissolved and disappeared into blood flow.
- a tube for connecting blood vessels which is made of a composition comprising to percent by weight of sucrose, 6 to 25 percent by weight of a crystallization inhibitor selected from the group consisting of glucose, lactose and maltose, and 2 to 10 percent by weight of an elasticizer selected from the group consisting of dextran and dextrin on the basis of the total weight of the composition.
- composition comprises an antimicrobial agent.
- composition comprises a blood coagulation inhibitor.
- the blood coagulation inhibitor is mucopolysaccharide or heparin.
Abstract
A tube readily soluble into blood and useful as the support for connecting blood vessels, which is made of a composition comprising 70 to 90 percent by weight of sucrose, 6 to 25 percent by weight of a crystallization inhibitor therefor and 2 to 10 percent by weight of an elasticizer, shaped in a cylinder, Tletter or Y-letter form, tapered at both ends and provided grooves or protuberances circumferentially on the outer surface.
Description
United States Patent Suzuki [451 Aug. 15, 1972 FOREIGN PATENTS OR APPLICATIONS 591,509 3/1946 Great Britain ..128/334 R [72] Inventor: Jiro Suzuki, Sendai, Japan OTHER PUBLICATIONS [73] Assignee: Dainippon Pharmaceutical Co., Ltd.,
Osaka-shi, Osaka-fu, Ja a Andrews et a1. Surgery, V01. 66 No. 3-pp. 535- 539 22' Filed: July 9, 1970 Sept 1969' [21] App]. No.: 53,454 Primary Examiner-Da1ton L. Truluck Attrney-Wenderoth, Lind & Ponack [52] US. Cl. ..l28/334R 3/1 51 rm.c1...., ..A61b 1 1/11 [571 ABSTRAcT Fle|d0fSe8P|I--123/334 334 335.5, A tube readily soluble into blood and useful as the 3/ 1; 424/ i 99/ 1 38 support for connecting blood vessels, which is made of a composition comprising to percent by weight [56] References Cned of sucrose, 6 to 25 percent by weight of a crystalliza- UNITED STATES PATENTS tion inhibitor therefor and 2 to percent by weight of an elasticizer, shaped in a cylinder, T-letter or Y- R letter form tapered at ends and provided grooves O u or on uter slug 2,953,497 9/1960 Press ..424/35 X f 3,155,095 11/1964 Brown ..l28/334 C 3,496,939 2/1970 Odiaga et a1 128/334 R 10 Claims, 8 Drawing Figures "K; ff l I 4;; I
Patented Aug. 15, 1972 FIGIQ FIGIA FIGZD INVENTOR JIRO SU di fl BY Wmf, zfldgPwa ATTORNEYS TUBE FOR CONNECTING BLOOD VESSELS The present invention relates to a tube for connecting blood vessels. It also relates to a method for preparation of such tube. It further relates to a method for connecting blood vessels by the aid of such tube.
Suture technique of blood vessels was started by Hovoch early in 1800. Recently, further progress in small vascular surgery was made by Jacobson who introduced microstructure technique, and stapling technique has been developed with various new stapling instruments too. But, usual apparatuses of stapling or suture technique are not applicable to intracranial vascular surgery, because these apparatuses are too large to manipulate. in very small operative fields. In addition, there is a danger of injuring to other surrounding important tissues such as cranial nerves, brain tissues and many small vessels.
In order to apply even to deeply located blood vessels as cerebral ones, attempts have been made on nonsuture vascular anastomosis utilizing plastic adhesives, which is easy to manipulate and less time consuming and does not need any large supplementary instruments. In such non-suture vascular anastomosis, a support material shaped in, for instance, tube or rod is inserted to the lumens of both vascular ends, a plastic ad hesive is applied to this anastomotic portion and blood flow is re-established so that, after a while, the support material dissolves into blood.
I As understood from such technique, the support material should meet at least the following three requirements: (I) exerting no materialtoxicity on living bodies such as animals and human beings; (2) having such rigidity as can be readily inserted into vascular lumens; and (3 being soluble with ease into blood so as to recover smooth flow of blood as early as possible. Although various materials and shape have been proposed for such support, satisfaction has been not fully obtained on any proposal.
As the result of the study for a long time, it has now been found that a certain composition comprising sucrose as the main component meets the said requirements and is an ideal material for such support. On this finding, there has been produced a tube made of the said composition and shaped in such form as being easily inserted in and difficultly slipped out of vascular lumens, and it has been confirmed that the vascular anastomosis can be accomplished quite successfully in various blood vessels including diseased vessels like atherosclerotic arteries and deeply located vessels as cerebral ones. The present invention is based on these finding and confirmation.
Accordingly, a basic object of the present invention is to embody a tube useful as the support on non-suture vascular anastomosis. Another object of this invention is to embody a method for preparation of such tube. A further object of the invention is to embody a method for connecting vascular vessels by the aid of such tube. A still further object of the invention is to embody a composition suitable for preparation of such tube. These and other objects of the invention will be apparent to those conversant with the art to which the present invention pertains from the above and subsequent descriptions.
The following is a brief description of the drawings. FIG. 1 shows the front views of the tubes which are three typical embodiments of the invention. That is,
FIG. 1 (A) shows a cylindrical tube FIG. 1 (B) shows a T-letter shaped tube and FIG. 1 (C) shows a Y-letter shaped tube.
FIG. 2 illustrates the steps for connecting blood ves sels according to the present invention. FIGS. 2 (A) and (B) show, respectively, two blood vessels to be connected each other at the section surface and a spindle tube (same as shown in FIG. 1 (A) to be used as the connection between the blood vessels.
FIG. 2 (C) shows the intermediate state for connection wherein both ends of the tube, are inserted into the lumens of the blood vessels. FIG. 2 (D) shows perfection of the insertion wherein two ring clips are placed on the outer surfaces of the blood vessels. FIG. 2 (E), shows the state after accomplishment of the connection where the tube dissolved and disappears into blood flow.
The tube of the present invention is made of a composition comprising sucrose as the main component, a crystallization inhibitor therefor and an elasticizer.
As the crystallization inhibitor, there are exemplified glucose, lactose, maltose, etc. Examples of the elasticizer are dextran, dextrin, etc.
The weight ratio of the components affects the solubility in blood flow and the mechanical strength of the resulting tube and may be varied with the place to which the tube is applied. Usually, the composition includes to percent 90by weight of sucrose, 6 to 25 percent by weight of the crystallization inhibitor and 2 to 10 percent by weight of the elasticizer on the basis of the weight of the composition. The most preferable weight ratio at present is sucrose the crystallization inhibitor the elasticizer= 80 l6 4.
In addition to the said essential components, the composition may include an antimicrobial agent, a blood coagulation inhibitor (e.g., mucopolysaccharides, heparin) and any other additive.
For preparation of the tube using such composition, the said essential components with or without the said optional components are first dissolved into water. The resultant solution is heated up to to C. l-Ieating above 170 C is not favorable, because caramelization is caused and the caramelized product is not suitably used for the object of the invention. The heated solution is then cooled to about 60 C for obtaining a soft, glassy material, from which a long pipe is drawn in the same manner as adopted on the manufacture of a glass pipe. The pipe is then cut at a proper length to make numerous pieces of tubes, each of which is then preferably tapered at both ends so as to be easily inserted to vascular ends and also favorably provided with grooves or protuberances circumferentially on the outer surface for preventing from slipping out of vascular ends.
Alternatively, the soft, glassy material may be shaped directily into a tube by the use of a mold. In this case, the tapering and/or the formation of grooves or protuberances may be accomplished simultaneously.
The thus obtained tube is of hard, glassy quality and usually stored under the condition prevented from moisture.
Prior to storage or use, the tube may be dipped in a solution of the antimicrobial agent and/or the blood coagulation inhibitor and then dried to make a film of such agents on the surface.
A practical and presently-preferred embodiment of the invention is illustratively shown in the following Example.
ELE
A solution of 80 g of sucrose, 16 g of glucose and 4 g of dextrin in 200 g of water is gradually heated up to 160 C and then allowed to stand for cooling. After cooled to 80 C, the solution is kept in a warming room and gradually cooled to about 70 C. After removal of a hard film formed on the surface, an appropriate amount of the resultant soft, glassy material is attached uniformly around a cylindrical stick made of polytetrafluoroethylene (Teflon) or glass (linoleic acid being applied previously on the surface in the latter case) so as to make a layer of 6 mm in thickness. When cooled to about 60 C, the stick is taken off, and the resultant hollow material is drawn to the directions of both ends while heating the central or trunk portion of the said material so as to make a pipe of l to mm in outer diameter. The pipe is cut by alcoholic vapor without affording any change on the inner diameter into some pieces of tubes, each tube being 10 to mm in length. A heated silver or platinum wire is contacted on the surface of the tube, and the tube is gradually rotated so that a groove is formed curcumferentially on the surface. In the same manner, another groove is provided on the surface at a distance from and parallel to the saidgroove. The grooved tube is irradiated under ultraviolet sterilization lamp and stored in a desiccator. The tube is readily soluble in water, sparingly soluble in anhydrous ethanol and materially insoluble in benzene, toluene, ether, fats and oils.
Some of the experiments on the connection using the above prepared tube are shown below.
EXPERIMENT l The tube of the invention was inserted to each one end of two vinyl tubes to be connected each other and, after applying an adhesive to the section surface of the vinyl tubes, they were brought into contact each other by the section surface. Then, stored blood at 37 C was flowed to the connected vinyl tube at a pressure of 130 mmI-ig. The tube of the invention dissolved completely within 40 seconds.
After transection of the artery occluded by two clamps, adventitia of vascular ends was stripped. The lumens of the vessels were irrigated with dilute heparinized saline solution. The tube of the invention having the same diameter as the internal diameter of the vessel was inserted to the both vascular ends. These ends were connected closely by the tube and two polyethylene sheathed clips were laid at the point of grooves of the tube from outside for fixation. Excessive blood and moisture at the anastomotic portion were removed by using a sponge and a very small amount of an adhesive (Aron Alpha A" composed of 98 percent alpha-ethylcyanoacrylate monomer plus 2 percent thickening agent and inhibitor) was applied directly by a polyethylene stick. After one minute for polymerization, the distal clamp was released first and, after confirmation of no occurrence of major bleeding, the proximal clamp was released. It was microscopically observed that anastomotic sites were covered smoothly by intimal proliferation within two weeks, and anastomosis was successfully accomplished.
Illustrating the present invention in reference to the attached drawings, FIG. 1 shows the front views of the tubes which are three typical embodiments of the invention. That is, FIG. 1 (A) shows a cylindrical tube (1) tapered at both ends and provided two grooves (11,11) circumferentially on the outer surface. FIG. 1 (B) shows a T-letter shaped tube (2) tapered at each end and provided three pairs of protuberances (21,21,21) circumferentially on the outer surface. FIG.
- l (C) shows a Y-letter shaped tube (3) tapered at each end and provided three grooves (31,31,31) circumferentially on the outer surface. The tapered portion is served for making it easy to insert into vascular lumens. The grooves and the protuberances are available for prevention of slipping out of vascular ends. If desired, ring clips may be placed on the groove or protuberance portion after insertion the tube in blood vessels.
FIG. 2 illustrates the steps for connecting blood vessels according to the present invention. FIGS. 2 (A) and (B) show respectively two blood vessels (4,4) to be connected each other at the section surface (41) and a spindle tube (5) (same as shown in FIG. 1 (A)) provided two grooves (51,51) before the connection. In FIG. 2 (C) showing the intermediate state for connection, both ends of the tube (5) are inserted into the lumens of the blood vessels (4,4). At this stage, an adhesive is applied to the section surface (41). In FIG. 2 (D) showing perfection of the insertion, two ring clips (6,6) are placed on the outer surfaces of the blood vessels at the places corresponding to the grooves of the tube now completely enclosed in the blood vessels for securing the connecting. In FIG. 2 (E), there is shown the state after accomplishment of the connection where the tube dissolved and disappeared into blood flow.
What is claimed is:
l. A tube for connecting blood vessels which is made of a composition comprising to percent by weight of sucrose, 6 to 25 percent by weight of a crystallization inhibitor selected from the group consisting of glucose, lactose and maltose, and 2 to 10 percent by weight of an elasticizer selected from the group consisting of dextran and dextrin on the basis of the total weight of the composition.
2. The tube according to claim 1, wherein the composition comprises an antimicrobial agent.
3. The tube according to claim 1, wherein the composition comprises a blood coagulation inhibitor.
4. The tube according to claim 1, wherein the blood coagulation inhibitor is mucopolysaccharide or heparin.
5. The tube according to claim 1, wherein the tube is shaped in a cylinder form.
6. The tube according to claim 1, wherein the tube is shaped in a T-letter form.
7. The tube according to claim 1, wherein the tube is shaped in a Y-letter form.
8. The tube according to claim 1, wherein the tube is tapered to the ends.
9. The tube according to claim 1, wherein grooves are provided circumferentiaily on the outer surface of the tube.
10. The tube according to claim 1, wherein protuberances are provided circumferentially on the outer sur- 5 face of the tube.
*k l l k
Claims (9)
- 2. The tube according to claim 1, wherein the composition comprises an antimicrobial agent.
- 3. The tube according to claim 1, wherein the composition comprises a blood coagulation inhibitor.
- 4. The tube according to claim 1, wherein the blood coagulation inhibitor is mucopolysaccharide or heparin.
- 5. The tube according to claim 1, wherein the tube is shaped in a cylinder form.
- 6. The tube according to claim 1, wherein the tube is shaped in a T-letter form.
- 7. The tube according to claim 1, wherein the tube is shaped in a Y-letter form.
- 8. The tube according to claim 1, wherein the tube is tapered to the ends.
- 9. The tube according to claim 1, wherein grooves are provided circumferentially on the outer surface of the tube.
- 10. The tube according to claim 1, wherein protuberances are provided circumferentially on the outer surface of the tube.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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US5345470A | 1970-07-09 | 1970-07-09 |
Publications (1)
Publication Number | Publication Date |
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US3683926A true US3683926A (en) | 1972-08-15 |
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US53454A Expired - Lifetime US3683926A (en) | 1970-07-09 | 1970-07-09 | Tube for connecting blood vessels |
Country Status (1)
Country | Link |
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US (1) | US3683926A (en) |
Cited By (161)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3833002A (en) * | 1973-09-10 | 1974-09-03 | J Palma | Apparatus for aiding severed nerves to join |
US3924274A (en) * | 1973-07-07 | 1975-12-09 | Friedrichsfeld Gmbh | An adjunct and method for facilitating implantation of joint prostheses |
US4118806A (en) * | 1976-02-04 | 1978-10-10 | Thermo Electron Corporation | Prosthetic blood vessel |
US4214586A (en) * | 1978-11-30 | 1980-07-29 | Ethicon, Inc. | Anastomotic coupling device |
US4267842A (en) * | 1979-07-09 | 1981-05-19 | Archibald Steven L | Micro-arterial sleeve-grip |
EP0070923A2 (en) * | 1981-07-27 | 1983-02-09 | American Cyanamid Company | Anastomotic device and method |
US4418693A (en) * | 1980-12-10 | 1983-12-06 | Leveen Eric G | Vein and tubing passer surgical instrument |
EP0119848A2 (en) * | 1983-03-17 | 1984-09-26 | Ethicon, Inc. | Anastomotic coupling device |
US4503568A (en) * | 1981-11-25 | 1985-03-12 | New England Deaconess Hospital | Small diameter vascular bypass and method |
EP0158316A2 (en) * | 1984-04-10 | 1985-10-16 | Walsh Manufacturing (Mississauga) Limited | Anastomosis devices and kit |
US4573471A (en) * | 1984-07-09 | 1986-03-04 | Rudner Merritt A | Prosthetic apparatus for surgical anastomosis |
US4588624A (en) * | 1982-05-14 | 1986-05-13 | Astra Meditec Ab | Articles exhibiting a biocompatible surface layer |
US4593693A (en) * | 1985-04-26 | 1986-06-10 | Schenck Robert R | Methods and apparatus for anastomosing living vessels |
US4607637A (en) * | 1983-07-22 | 1986-08-26 | Anders Berggren | Surgical instrument for performing anastomosis with the aid of ring-like fastening elements and the fastening elements for performing anastomosis |
US4624257A (en) * | 1982-06-24 | 1986-11-25 | Anders Berggren | Surgical instrument for performing anastomosis |
FR2586347A1 (en) * | 1985-08-20 | 1987-02-27 | Inoteb Sarl | Emergency treatment apparatus for overloading and meteorism in animals |
US4690684A (en) * | 1985-07-12 | 1987-09-01 | C. R. Bard, Inc. | Meltable stent for anastomosis |
US4787386A (en) * | 1984-04-10 | 1988-11-29 | Idea Research Investment Fund, Inc. | Anastomosis devices, and kits |
US4851001A (en) * | 1987-09-17 | 1989-07-25 | Taheri Syde A | Prosthetic valve for a blood vein and an associated method of implantation of the valve |
US4917087A (en) * | 1984-04-10 | 1990-04-17 | Walsh Manufacturing (Mississuaga) Limited | Anastomosis devices, kits and method |
US5064057A (en) * | 1987-04-30 | 1991-11-12 | Ajinomoto Co., Inc. | Support for anastomosing or connecting living organs |
US5139505A (en) * | 1989-06-30 | 1992-08-18 | Euroresearch S.R.L. | Device consisting of a heterologous collagen tube for use in hollow organ sutures |
US5141516A (en) * | 1989-07-26 | 1992-08-25 | Detweiler Mark B | Dissolvable anastomosis stent and method for using the same |
US5180392A (en) * | 1988-02-01 | 1993-01-19 | Einar Skeie | Anastomotic device |
US5192289A (en) * | 1989-03-09 | 1993-03-09 | Avatar Design And Development, Inc. | Anastomosis stent and stent selection system |
FR2683141A1 (en) * | 1991-11-05 | 1993-05-07 | Richard Thierry | Connection device for organ vessel prostheses |
US5222964A (en) * | 1992-03-03 | 1993-06-29 | Cooper William I | Intraluminal stent |
US5332403A (en) * | 1992-08-17 | 1994-07-26 | Jack Kolff | LVAD with t-shape and unidirectional valve |
WO1994027506A2 (en) * | 1993-05-21 | 1994-12-08 | Biovision Gmbh Entwicklung, Herstellung Und Vertrieb Von Biomaterialien | Anastomosis device |
WO1995012368A1 (en) * | 1993-11-04 | 1995-05-11 | Kaupallisteollinen Is-Välitys Oy Lkv | Connector for stopping bleeding from severed blood-vessels |
US5527324A (en) * | 1994-09-07 | 1996-06-18 | Krantz; Kermit E. | Surgical stent |
EP0749731A2 (en) * | 1995-06-12 | 1996-12-27 | Advanced Cardiovascular Systems, Inc. | Coupling device and method of use |
US5611794A (en) * | 1990-10-11 | 1997-03-18 | Lasersurge, Inc. | Clamp for approximating tissue sections |
US5868765A (en) * | 1998-06-10 | 1999-02-09 | Surgical Innovations, Llc | Device and method for the surgical anastomasis of tubular structures |
US5868763A (en) * | 1996-09-16 | 1999-02-09 | Guidant Corporation | Means and methods for performing an anastomosis |
WO1999033403A1 (en) | 1997-12-31 | 1999-07-08 | Kensey Nash Corporation | Bifurcated connector system for coronary bypass grafts |
US6007576A (en) * | 1998-02-06 | 1999-12-28 | Mcclellan; Scott B. | End to side anastomic implant |
US6017352A (en) * | 1997-09-04 | 2000-01-25 | Kensey Nash Corporation | Systems for intravascular procedures and methods of use |
US6019788A (en) * | 1996-11-08 | 2000-02-01 | Gore Enterprise Holdings, Inc. | Vascular shunt graft and junction for same |
US6030395A (en) * | 1997-05-22 | 2000-02-29 | Kensey Nash Corporation | Anastomosis connection system |
US6063114A (en) * | 1997-09-04 | 2000-05-16 | Kensey Nash Corporation | Connector system for vessels, ducts, lumens or hollow organs and methods of use |
US6110188A (en) * | 1998-03-09 | 2000-08-29 | Corvascular, Inc. | Anastomosis method |
US6176864B1 (en) * | 1998-03-09 | 2001-01-23 | Corvascular, Inc. | Anastomosis device and method |
US6231506B1 (en) | 1999-05-04 | 2001-05-15 | Cardiothoracic Systems, Inc. | Method and apparatus for creating a working opening through an incision |
US6241741B1 (en) | 1998-03-09 | 2001-06-05 | Corvascular Surgical Systems, Inc. | Anastomosis device and method |
US6241747B1 (en) * | 1993-05-03 | 2001-06-05 | Quill Medical, Inc. | Barbed Bodily tissue connector |
US20010003795A1 (en) * | 1997-07-22 | 2001-06-14 | Mitta Suresh | Catheter system and method for posterior epicardial revascularization and intracardiac surgery on a beating heart |
US6283912B1 (en) | 1999-05-04 | 2001-09-04 | Cardiothoracic Systems, Inc. | Surgical retractor platform blade apparatus |
US6290644B1 (en) | 1996-02-20 | 2001-09-18 | Cardiothoracic Systems, Inc. | Surgical instruments and procedures for stabilizing a localized portion of a beating heart |
US6315752B1 (en) | 1999-03-26 | 2001-11-13 | Scimed Life Systems, Inc. | Implantable bypass device |
US6315717B1 (en) | 1996-02-20 | 2001-11-13 | Cardiothoracic Systems, Inc. | Surgical instruments for stabilizing the beating heart during coronary artery bypass graft surgery |
WO2002013675A2 (en) * | 2000-08-10 | 2002-02-21 | Dialysis Access Solutions, Inc. | Distally narrowed vascular grafts |
US6394951B1 (en) | 1996-02-20 | 2002-05-28 | Cardiothoracic Systems, Inc. | Surgical instruments and procedures for stabilizing the beating heart during coronary artery bypass graft surgery |
US20020065451A1 (en) * | 1997-09-17 | 2002-05-30 | Spence Paul A. | Device to permit offpump beating heart coronary bypass surgery |
US6406424B1 (en) | 1999-09-16 | 2002-06-18 | Williamson, Iv Warren P. | Tissue stabilizer having an articulating lift element |
US6488692B1 (en) | 1996-09-16 | 2002-12-03 | Origin Medsystems, Inc. | Access and cannulation device and method for rapidly placing same and for rapidly closing same in minimally invasive surgery |
US6511416B1 (en) | 1999-08-03 | 2003-01-28 | Cardiothoracic Systems, Inc. | Tissue stabilizer and methods of use |
US6565581B1 (en) | 1996-09-16 | 2003-05-20 | Origin Medsystems, Inc. | Apparatus and method for performing an anastomosis |
US20030114923A1 (en) * | 2001-11-14 | 2003-06-19 | Swanick Thomas M. | Graft and method of making |
US6582409B1 (en) * | 1997-02-07 | 2003-06-24 | Graftcath, Inc. | Hemodialysis and vascular access systems |
US6585762B1 (en) | 2000-08-10 | 2003-07-01 | Paul Stanish | Arteriovenous grafts and methods of implanting the same |
US6589278B1 (en) | 1997-05-17 | 2003-07-08 | Impra, Inc. | Vascular prosthesis |
US20030130671A1 (en) * | 1999-11-23 | 2003-07-10 | Duhaylongsod Francis G. | Anastomosis device and method |
US6599310B2 (en) | 2001-06-29 | 2003-07-29 | Quill Medical, Inc. | Suture method |
WO2003061487A1 (en) * | 2002-01-25 | 2003-07-31 | Erbe Elektromedizin Gmbh | Device for the production of anastomoses between hollow organs |
US6626830B1 (en) | 1999-05-04 | 2003-09-30 | Cardiothoracic Systems, Inc. | Methods and devices for improved tissue stabilization |
WO2003090840A1 (en) * | 2002-04-23 | 2003-11-06 | Medtronic, Inc. | Implantable medical catheter connector for medical tubing with anchoring features |
US6685632B1 (en) | 1999-05-04 | 2004-02-03 | Cardiothoracic Systems, Inc. | Surgical instruments for accessing and stabilizing a localized portion of a beating heart |
US20040030354A1 (en) * | 2002-08-09 | 2004-02-12 | Leung Jeffrey C. | Suture anchor and method |
US20040054405A1 (en) * | 2002-09-12 | 2004-03-18 | Edrich Health Technologies, Inc., A Corporation Of The State Of Delaware | Prosthetic vascular graft connector |
US20040073282A1 (en) * | 2001-08-06 | 2004-04-15 | Paul Stanish | Distally-narrowed vascular grafts and methods of using same for making artery-to-vein and artery-to-artery connections |
US20040088003A1 (en) * | 2002-09-30 | 2004-05-06 | Leung Jeffrey C. | Barbed suture in combination with surgical needle |
WO2004041074A2 (en) * | 2002-11-05 | 2004-05-21 | Damage Control Surgical Technologies, Inc. | Method and device for temporary emergency vessel anastomoses |
US6743243B1 (en) | 1998-03-20 | 2004-06-01 | Sumit Roy | Support device for endoscopic suturless anastomosis |
US6743170B1 (en) | 1997-09-17 | 2004-06-01 | Cardiothoracic Systems, Inc. | Device to permit offpump beating heart coronary bypass surgery |
US6746480B2 (en) * | 1998-12-08 | 2004-06-08 | Bard Peripheral Vascular, Inc. | Flanged graft for end-to-side anastomosis |
US6758808B2 (en) | 2001-01-24 | 2004-07-06 | Cardiothoracic System, Inc. | Surgical instruments for stabilizing a localized portion of a beating heart |
US6811555B1 (en) | 1996-09-16 | 2004-11-02 | Origin Medsystems, Inc. | Method and apparatus for performing anastomosis with eversion of tissue edges and joining of exposed intima of the everted tissue |
US20040220643A1 (en) * | 2001-04-27 | 2004-11-04 | Medtronic, Inc. | Implantable medical device with rechargeable thin-film microbattery power source |
US20040237736A1 (en) * | 2001-08-31 | 2004-12-02 | Genova Perry A. | Method of forming barbs on a suture and apparatus for performing same |
US20050004584A1 (en) * | 2000-09-25 | 2005-01-06 | Cohesion Technologies, Inc. | Resorbable anastomosis stents and plugs and their use in patients |
US20050021060A1 (en) * | 2001-02-27 | 2005-01-27 | Davis John W. | Device, tools and methods for performing anastomosis |
US6852075B1 (en) | 1996-02-20 | 2005-02-08 | Cardiothoracic Systems, Inc. | Surgical devices for imposing a negative pressure to stabilize cardiac tissue during surgery |
GB2407773A (en) * | 2003-11-06 | 2005-05-11 | Martin Lister | Connector for blood vessels |
US20050137614A1 (en) * | 2003-10-08 | 2005-06-23 | Porter Christopher H. | System and method for connecting implanted conduits |
US20050165428A1 (en) * | 2000-09-25 | 2005-07-28 | Franco Kenneth L. | Absorable surgical structure |
US6926724B1 (en) * | 1999-05-04 | 2005-08-09 | City Of Hope | Visceral anastomotic device and method of using same |
US6969349B1 (en) | 1997-09-17 | 2005-11-29 | Origin Medsystem, Inc. | Device to permit offpump beating heart coronary bypass surgery |
US20060030935A1 (en) * | 1996-02-28 | 2006-02-09 | Bard Peripheral Vascular, Inc. | Flanged graft for end-to-side anastomosis |
US20060064159A1 (en) * | 2003-10-08 | 2006-03-23 | Porter Christopher H | Device and method for vascular access |
US20060111742A1 (en) * | 2001-06-29 | 2006-05-25 | Andrew Kaplan | Suture method |
US20070005128A1 (en) * | 2005-07-01 | 2007-01-04 | C. R. Bard, Inc. | Flanged graft with trim lines |
US7179224B2 (en) | 2003-12-30 | 2007-02-20 | Cardiothoracic Systems, Inc. | Organ manipulator and positioner and methods of using the same |
US7219671B2 (en) | 1995-04-10 | 2007-05-22 | Cardiothoracic Systems, Inc. | Method for coronary artery bypass |
US20070167901A1 (en) * | 2005-11-17 | 2007-07-19 | Herrig Judson A | Self-sealing residual compressive stress graft for dialysis |
US20070198077A1 (en) * | 2006-01-20 | 2007-08-23 | Cully Edward H | Device for rapid repair of body conduits |
US20070239180A1 (en) * | 2006-04-06 | 2007-10-11 | Synovis Life Technologies, Inc. | Method and assembly for anastomosis |
US20080045985A1 (en) * | 2006-06-21 | 2008-02-21 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for joining non-conjoined lumens |
US20080262519A1 (en) * | 2006-06-21 | 2008-10-23 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for joining non-conjoined lumens |
US7479104B2 (en) | 2003-07-08 | 2009-01-20 | Maquet Cardiovascular, Llc | Organ manipulator apparatus |
US20090187199A1 (en) * | 2006-06-21 | 2009-07-23 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for joining non-conjoined lumens |
US20090281560A1 (en) * | 2008-05-06 | 2009-11-12 | Wexner Steven D | Method for anastomosis surgery using zip-ties |
US7624487B2 (en) | 2003-05-13 | 2009-12-01 | Quill Medical, Inc. | Apparatus and method for forming barbs on a suture |
US7708769B1 (en) | 1997-03-13 | 2010-05-04 | United States Surgical Corporation | Graft attachment assembly |
US20100153335A1 (en) * | 2008-12-12 | 2010-06-17 | Microsoft Corporation | Synchronizing multiple classes with disparate schemas in the same collection |
US20100280598A1 (en) * | 2007-12-27 | 2010-11-04 | C.R. Bard, Inc. | Vascular graft prosthesis having a reinforced margin for enhanced anastomosis |
US20100298871A1 (en) * | 2004-05-14 | 2010-11-25 | Quill Medical, Inc. | Self-retaining wound closure device including an anchoring loop |
US20100298876A1 (en) * | 2002-09-30 | 2010-11-25 | Quill Medical, Inc. | Self-retaining sutures having effective holding strength and tensile strength |
US20110009802A1 (en) * | 2009-07-07 | 2011-01-13 | Marwan Tabbara | Surgical Methods, Devices, and Kits |
US20110066170A1 (en) * | 2009-09-14 | 2011-03-17 | Circulite, Inc. | Endovascular anastomotic connector device, delivery system, and methods of delivery and use |
US20110087063A1 (en) * | 2009-10-08 | 2011-04-14 | Circulite, Inc. | Two piece endovascular anastomotic connector |
US7931590B2 (en) | 2002-10-29 | 2011-04-26 | Maquet Cardiovascular Llc | Tissue stabilizer and methods of using the same |
US8079973B2 (en) | 2008-03-05 | 2011-12-20 | Hemosphere Inc. | Vascular access system |
US8083664B2 (en) | 2005-05-25 | 2011-12-27 | Maquet Cardiovascular Llc | Surgical stabilizers and methods for use in reduced-access surgical sites |
US8118834B1 (en) | 2007-12-20 | 2012-02-21 | Angiotech Pharmaceuticals, Inc. | Composite self-retaining sutures and method |
US8216273B1 (en) | 2008-02-25 | 2012-07-10 | Ethicon, Inc. | Self-retainers with supporting structures on a suture |
JP2013534444A (en) * | 2010-07-09 | 2013-09-05 | ハイライフ エスエーエス | Transcatheter atrioventricular valve prosthesis |
WO2013185484A1 (en) * | 2012-06-14 | 2013-12-19 | Min Yike | Suture-less wound closure device for lumen within human body |
US8615856B1 (en) | 2008-01-30 | 2013-12-31 | Ethicon, Inc. | Apparatus and method for forming self-retaining sutures |
US8641732B1 (en) | 2008-02-26 | 2014-02-04 | Ethicon, Inc. | Self-retaining suture with variable dimension filament and method |
US20140155804A1 (en) * | 2009-07-07 | 2014-06-05 | Marwan Tabbara | Surgical devices and kits |
US8771313B2 (en) | 2007-12-19 | 2014-07-08 | Ethicon, Inc. | Self-retaining sutures with heat-contact mediated retainers |
US8777987B2 (en) | 2007-09-27 | 2014-07-15 | Ethicon, Inc. | Self-retaining sutures including tissue retainers having improved strength |
US8793863B2 (en) | 2007-04-13 | 2014-08-05 | Ethicon, Inc. | Method and apparatus for forming retainers on a suture |
US20140276326A1 (en) * | 2011-05-16 | 2014-09-18 | Berlin Heart Gmbh | Connection system for creating a connection channel for bodily fluids |
US20140309654A1 (en) * | 2010-12-06 | 2014-10-16 | Circ Medtech Ltd. | Support element for circumcision and system comprising the same |
US8876865B2 (en) | 2008-04-15 | 2014-11-04 | Ethicon, Inc. | Self-retaining sutures with bi-directional retainers or uni-directional retainers |
US8875607B2 (en) | 2008-01-30 | 2014-11-04 | Ethicon, Inc. | Apparatus and method for forming self-retaining sutures |
US8916077B1 (en) | 2007-12-19 | 2014-12-23 | Ethicon, Inc. | Self-retaining sutures with retainers formed from molten material |
US8932328B2 (en) | 2008-11-03 | 2015-01-13 | Ethicon, Inc. | Length of self-retaining suture and method and device for using the same |
US8961560B2 (en) | 2008-05-16 | 2015-02-24 | Ethicon, Inc. | Bidirectional self-retaining sutures with laser-marked and/or non-laser marked indicia and methods |
USRE45426E1 (en) | 1997-05-21 | 2015-03-17 | Ethicon, Inc. | Surgical methods using one-way suture |
US9022998B2 (en) | 2010-02-26 | 2015-05-05 | Maquet Cardiovascular Llc | Blower instrument, apparatus and methods of using |
US20150157836A1 (en) * | 2008-01-28 | 2015-06-11 | Peter Mats Forsell | Implantable drainage device |
US20150157324A1 (en) * | 2013-12-06 | 2015-06-11 | W. L. Gore & Associates, Inc. | Anastomotic connectors |
US20150238192A1 (en) * | 2004-10-15 | 2015-08-27 | Covidien Lp | Seal element for anastomosis |
US9125647B2 (en) | 2008-02-21 | 2015-09-08 | Ethicon, Inc. | Method and apparatus for elevating retainers on self-retaining sutures |
RU2569604C1 (en) * | 2014-07-25 | 2015-11-27 | Общество с ограниченной ответственностью "Научно-технический центр "Мепотекс" | Blood, blood substitute or infusion solution line |
US9248580B2 (en) | 2002-09-30 | 2016-02-02 | Ethicon, Inc. | Barb configurations for barbed sutures |
CN106422049A (en) * | 2016-10-31 | 2017-02-22 | 黄剑 | Bridging stent based on temporary blood circulation restoring application and processing method thereof |
US9655605B2 (en) | 2010-06-14 | 2017-05-23 | Maquet Cardiovascular Llc | Surgical instruments, systems and methods of use |
US9675341B2 (en) | 2010-11-09 | 2017-06-13 | Ethicon Inc. | Emergency self-retaining sutures and packaging |
US9814869B1 (en) | 1999-06-15 | 2017-11-14 | C.R. Bard, Inc. | Graft-catheter vascular access system |
US9955962B2 (en) | 2010-06-11 | 2018-05-01 | Ethicon, Inc. | Suture delivery tools for endoscopic and robot-assisted surgery and methods |
US10188384B2 (en) | 2011-06-06 | 2019-01-29 | Ethicon, Inc. | Methods and devices for soft palate tissue elevation procedures |
US20190038288A1 (en) * | 2016-02-05 | 2019-02-07 | Chu De Nice | Anastomotic connector |
US10213590B2 (en) | 2011-09-06 | 2019-02-26 | Merit Medical Systems, Inc. | Vascular access system with connector |
US10420546B2 (en) | 2010-05-04 | 2019-09-24 | Ethicon, Inc. | Self-retaining systems having laser-cut retainers |
US10492780B2 (en) | 2011-03-23 | 2019-12-03 | Ethicon, Inc. | Self-retaining variable loop sutures |
US10682453B2 (en) | 2013-12-20 | 2020-06-16 | Merit Medical Systems, Inc. | Vascular access system with reinforcement member |
US10792413B2 (en) | 2008-03-05 | 2020-10-06 | Merit Medical Systems, Inc. | Implantable and removable customizable body conduit |
US10925710B2 (en) | 2017-03-24 | 2021-02-23 | Merit Medical Systems, Inc. | Subcutaneous vascular assemblies for improving blood flow and related devices and methods |
US11007296B2 (en) | 2010-11-03 | 2021-05-18 | Ethicon, Inc. | Drug-eluting self-retaining sutures and methods relating thereto |
US11026704B2 (en) | 2017-03-06 | 2021-06-08 | Merit Medical Systems, Inc. | Vascular access assembly declotting systems and methods |
US11179543B2 (en) | 2017-07-14 | 2021-11-23 | Merit Medical Systems, Inc. | Releasable conduit connectors |
US11331458B2 (en) | 2017-10-31 | 2022-05-17 | Merit Medical Systems, Inc. | Subcutaneous vascular assemblies for improving blood flow and related devices and methods |
US11383072B2 (en) | 2017-01-12 | 2022-07-12 | Merit Medical Systems, Inc. | Methods and systems for selection and use of connectors between conduits |
US11413043B2 (en) | 2016-11-10 | 2022-08-16 | Merit Medical Systems, Inc. | Anchor device for vascular anastomosis |
US11590010B2 (en) | 2017-01-25 | 2023-02-28 | Merit Medical Systems, Inc. | Methods and systems for facilitating laminar flow between conduits |
US11751876B2 (en) | 2019-05-07 | 2023-09-12 | Easyflomicro Inc. | Apparatuses for anastomosis of tubular vessels and related methods |
US11911585B2 (en) | 2017-07-20 | 2024-02-27 | Merit Medical Systems, Inc. | Methods and systems for coupling conduits |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2127903A (en) * | 1936-05-05 | 1938-08-23 | Davis & Geck Inc | Tube for surgical purposes and method of preparing and using the same |
GB591509A (en) * | 1945-03-26 | 1947-08-20 | Raymond Nigel Roy | A soluble lumen suture support |
US2903365A (en) * | 1957-01-22 | 1959-09-08 | Edward D O'brian | Confection structures |
US2953497A (en) * | 1953-06-03 | 1960-09-20 | Howard A Press | Therapeutic tablets |
US3155095A (en) * | 1961-02-07 | 1964-11-03 | Adolph M Brown | Anastomosis method and means |
US3496939A (en) * | 1967-08-09 | 1970-02-24 | Carlos E Odiaga | Surgical anastomotic sleeve coupling |
-
1970
- 1970-07-09 US US53454A patent/US3683926A/en not_active Expired - Lifetime
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2127903A (en) * | 1936-05-05 | 1938-08-23 | Davis & Geck Inc | Tube for surgical purposes and method of preparing and using the same |
GB591509A (en) * | 1945-03-26 | 1947-08-20 | Raymond Nigel Roy | A soluble lumen suture support |
US2953497A (en) * | 1953-06-03 | 1960-09-20 | Howard A Press | Therapeutic tablets |
US2903365A (en) * | 1957-01-22 | 1959-09-08 | Edward D O'brian | Confection structures |
US3155095A (en) * | 1961-02-07 | 1964-11-03 | Adolph M Brown | Anastomosis method and means |
US3496939A (en) * | 1967-08-09 | 1970-02-24 | Carlos E Odiaga | Surgical anastomotic sleeve coupling |
Non-Patent Citations (1)
Title |
---|
Andrews et al. Surgery, Vol. 66 No. 3 pp. 535 539 Sept. 1969 * |
Cited By (339)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3924274A (en) * | 1973-07-07 | 1975-12-09 | Friedrichsfeld Gmbh | An adjunct and method for facilitating implantation of joint prostheses |
US3833002A (en) * | 1973-09-10 | 1974-09-03 | J Palma | Apparatus for aiding severed nerves to join |
US4118806A (en) * | 1976-02-04 | 1978-10-10 | Thermo Electron Corporation | Prosthetic blood vessel |
US4214586A (en) * | 1978-11-30 | 1980-07-29 | Ethicon, Inc. | Anastomotic coupling device |
US4267842A (en) * | 1979-07-09 | 1981-05-19 | Archibald Steven L | Micro-arterial sleeve-grip |
US4418693A (en) * | 1980-12-10 | 1983-12-06 | Leveen Eric G | Vein and tubing passer surgical instrument |
EP0070923A3 (en) * | 1981-07-27 | 1984-02-01 | American Cyanamid Company | Anastomotic device and method |
EP0070923A2 (en) * | 1981-07-27 | 1983-02-09 | American Cyanamid Company | Anastomotic device and method |
US4503568A (en) * | 1981-11-25 | 1985-03-12 | New England Deaconess Hospital | Small diameter vascular bypass and method |
US4673584A (en) * | 1982-05-14 | 1987-06-16 | Astra Meditec Ab | Process for providing articles with a biocompatible surface layer |
US4588624A (en) * | 1982-05-14 | 1986-05-13 | Astra Meditec Ab | Articles exhibiting a biocompatible surface layer |
US4624257A (en) * | 1982-06-24 | 1986-11-25 | Anders Berggren | Surgical instrument for performing anastomosis |
US4917090A (en) * | 1982-06-24 | 1990-04-17 | Unilink, Inc. | Method for performing an anastomosis |
EP0119848A2 (en) * | 1983-03-17 | 1984-09-26 | Ethicon, Inc. | Anastomotic coupling device |
EP0119848A3 (en) * | 1983-03-17 | 1986-02-26 | Ethicon, Inc. | Anastomotic coupling device |
US4607637A (en) * | 1983-07-22 | 1986-08-26 | Anders Berggren | Surgical instrument for performing anastomosis with the aid of ring-like fastening elements and the fastening elements for performing anastomosis |
EP0158316A2 (en) * | 1984-04-10 | 1985-10-16 | Walsh Manufacturing (Mississauga) Limited | Anastomosis devices and kit |
US4657019A (en) * | 1984-04-10 | 1987-04-14 | Idea Research Investment Fund, Inc. | Anastomosis devices and kits |
US4787386A (en) * | 1984-04-10 | 1988-11-29 | Idea Research Investment Fund, Inc. | Anastomosis devices, and kits |
US4917087A (en) * | 1984-04-10 | 1990-04-17 | Walsh Manufacturing (Mississuaga) Limited | Anastomosis devices, kits and method |
EP0158316A3 (en) * | 1984-04-10 | 1986-02-26 | Walsh Manufacturing (Mississauga) Limited | Anastomosis devices and kit |
US4573471A (en) * | 1984-07-09 | 1986-03-04 | Rudner Merritt A | Prosthetic apparatus for surgical anastomosis |
US4593693A (en) * | 1985-04-26 | 1986-06-10 | Schenck Robert R | Methods and apparatus for anastomosing living vessels |
US4690684A (en) * | 1985-07-12 | 1987-09-01 | C. R. Bard, Inc. | Meltable stent for anastomosis |
FR2586347A1 (en) * | 1985-08-20 | 1987-02-27 | Inoteb Sarl | Emergency treatment apparatus for overloading and meteorism in animals |
US5064057A (en) * | 1987-04-30 | 1991-11-12 | Ajinomoto Co., Inc. | Support for anastomosing or connecting living organs |
US4851001A (en) * | 1987-09-17 | 1989-07-25 | Taheri Syde A | Prosthetic valve for a blood vein and an associated method of implantation of the valve |
US5180392A (en) * | 1988-02-01 | 1993-01-19 | Einar Skeie | Anastomotic device |
US5192289A (en) * | 1989-03-09 | 1993-03-09 | Avatar Design And Development, Inc. | Anastomosis stent and stent selection system |
US5139505A (en) * | 1989-06-30 | 1992-08-18 | Euroresearch S.R.L. | Device consisting of a heterologous collagen tube for use in hollow organ sutures |
US5141516A (en) * | 1989-07-26 | 1992-08-25 | Detweiler Mark B | Dissolvable anastomosis stent and method for using the same |
US5611794A (en) * | 1990-10-11 | 1997-03-18 | Lasersurge, Inc. | Clamp for approximating tissue sections |
FR2683141A1 (en) * | 1991-11-05 | 1993-05-07 | Richard Thierry | Connection device for organ vessel prostheses |
US5222964A (en) * | 1992-03-03 | 1993-06-29 | Cooper William I | Intraluminal stent |
US5332403A (en) * | 1992-08-17 | 1994-07-26 | Jack Kolff | LVAD with t-shape and unidirectional valve |
US7226468B2 (en) | 1993-05-03 | 2007-06-05 | Quill Medical, Inc. | Barbed bodily tissue connector |
US20040093028A1 (en) * | 1993-05-03 | 2004-05-13 | Ruff Gregory L. | Barbed bodily tissue connector |
US8246652B2 (en) | 1993-05-03 | 2012-08-21 | Ethicon, Inc. | Suture with a pointed end and an anchor end and with equally spaced yieldable tissue grasping barbs located at successive axial locations |
US7806908B2 (en) | 1993-05-03 | 2010-10-05 | Quill Medical, Inc. | Barbed tissue connector |
US6241747B1 (en) * | 1993-05-03 | 2001-06-05 | Quill Medical, Inc. | Barbed Bodily tissue connector |
US20080221617A1 (en) * | 1993-05-03 | 2008-09-11 | Quill Medical, Inc. | Barbed tissue connector |
US20070208355A1 (en) * | 1993-05-03 | 2007-09-06 | Ruff Gregory L | Barbed tissue connector |
WO1994027506A2 (en) * | 1993-05-21 | 1994-12-08 | Biovision Gmbh Entwicklung, Herstellung Und Vertrieb Von Biomaterialien | Anastomosis device |
WO1994027506A3 (en) * | 1993-05-21 | 1995-01-05 | Biovision Gmbh | Anastomosis device |
WO1995012368A1 (en) * | 1993-11-04 | 1995-05-11 | Kaupallisteollinen Is-Välitys Oy Lkv | Connector for stopping bleeding from severed blood-vessels |
US5527324A (en) * | 1994-09-07 | 1996-06-18 | Krantz; Kermit E. | Surgical stent |
US7219671B2 (en) | 1995-04-10 | 2007-05-22 | Cardiothoracic Systems, Inc. | Method for coronary artery bypass |
EP0749731A2 (en) * | 1995-06-12 | 1996-12-27 | Advanced Cardiovascular Systems, Inc. | Coupling device and method of use |
US5728131A (en) * | 1995-06-12 | 1998-03-17 | Endotex Interventional Systems, Inc. | Coupling device and method of use |
EP0749731A3 (en) * | 1995-06-12 | 1997-11-12 | Endotex Interventional Systems, Inc. | Coupling device and method of use |
US7485090B2 (en) | 1996-02-20 | 2009-02-03 | Maquet Cardiovascular Llc | Surgical devices for imposing a negative pressure to stabilize cardiac tissue during surgery |
US6673013B2 (en) | 1996-02-20 | 2004-01-06 | Cardiothoracic Systems, Inc. | Surgical instruments and procedures for stabilizing the beating heart during coronary artery bypass graft surgery |
US7585277B2 (en) | 1996-02-20 | 2009-09-08 | Maquet Cardiovascular Llc | Surgical instruments and procedures for stabilizing the beating heart during coronary artery bypass graft surgery |
US6852075B1 (en) | 1996-02-20 | 2005-02-08 | Cardiothoracic Systems, Inc. | Surgical devices for imposing a negative pressure to stabilize cardiac tissue during surgery |
US7497824B2 (en) | 1996-02-20 | 2009-03-03 | Maquet Cardiovasculer, Llc | Surgical devices for imposing a negative pressure to stabilize cardiac tissue during surgery |
US6394951B1 (en) | 1996-02-20 | 2002-05-28 | Cardiothoracic Systems, Inc. | Surgical instruments and procedures for stabilizing the beating heart during coronary artery bypass graft surgery |
US6743169B1 (en) | 1996-02-20 | 2004-06-01 | Cardiothoracic Systems, Inc. | Surgical instruments and procedures for stabilizing the beating heart during coronary artery bypass graft surgery |
US8277476B2 (en) | 1996-02-20 | 2012-10-02 | Maguet Cardiovascular LLC | Surgical instruments and procedures for stabilizing the beating heart during coronary artery bypass graft |
US7335158B2 (en) | 1996-02-20 | 2008-02-26 | Cardiothoracic Systems, Inc. | Surgical devices for imposing a negative pressure to stabilize the cardiac tissue during surgery |
US20040087834A1 (en) * | 1996-02-20 | 2004-05-06 | Benetti Federico J. | Surgical instruments and procedures for stabilizing the beating heart during coronary artery bypass graft surgery |
US8382654B2 (en) | 1996-02-20 | 2013-02-26 | Maquet Cardiovascular Llc | Surgical devices for imposing a negative pressure to stabilize the cardiac tissue during surgery |
US6701930B2 (en) | 1996-02-20 | 2004-03-09 | Cardiothoracic Systems, Inc. | Surgical instruments and procedures for stabilizing the beating heart during coronary artery bypass graft surgery |
US7056287B2 (en) | 1996-02-20 | 2006-06-06 | Cardiothoracic Systems, Inc. | Surgical instruments and procedures for stabilizing the beating heart during coronary artery bypass graft surgery |
US6893391B2 (en) | 1996-02-20 | 2005-05-17 | Cardiothoracic Systems, Inc. | Surgical devices for imposing a negative pressure to stabilize cardiac tissue during surgery |
US6656113B2 (en) | 1996-02-20 | 2003-12-02 | Cardiothoracic System, Inc. | Surgical instruments and procedures for stabilizing a localized portion of a beating heart |
US6315717B1 (en) | 1996-02-20 | 2001-11-13 | Cardiothoracic Systems, Inc. | Surgical instruments for stabilizing the beating heart during coronary artery bypass graft surgery |
US6290644B1 (en) | 1996-02-20 | 2001-09-18 | Cardiothoracic Systems, Inc. | Surgical instruments and procedures for stabilizing a localized portion of a beating heart |
US6346077B1 (en) * | 1996-02-20 | 2002-02-12 | Cardiothoracic Systems, Inc. | Surgical instrument for stabilizing the beating heart during coronary artery bypass graft surgery |
US9028539B2 (en) | 1996-02-28 | 2015-05-12 | Bard Peripheral Vascular, Inc. | Flanged graft for end-to-side anastomosis |
US20060030935A1 (en) * | 1996-02-28 | 2006-02-09 | Bard Peripheral Vascular, Inc. | Flanged graft for end-to-side anastomosis |
US6811555B1 (en) | 1996-09-16 | 2004-11-02 | Origin Medsystems, Inc. | Method and apparatus for performing anastomosis with eversion of tissue edges and joining of exposed intima of the everted tissue |
US6565581B1 (en) | 1996-09-16 | 2003-05-20 | Origin Medsystems, Inc. | Apparatus and method for performing an anastomosis |
US20040220597A1 (en) * | 1996-09-16 | 2004-11-04 | Willis Geoffrey H. | Method and apparatus for performing anastomosis with eversion of tissue edges and joining of exposed intima of the everted tissue |
US5868763A (en) * | 1996-09-16 | 1999-02-09 | Guidant Corporation | Means and methods for performing an anastomosis |
US6652543B2 (en) | 1996-09-16 | 2003-11-25 | Origin Medsystems, Inc. | Means and method for performing an anastomosis |
US7497865B2 (en) | 1996-09-16 | 2009-03-03 | Maquet Cardiovascular, Llc | Method and apparatus for performing anastomosis with eversion of tissue edges and joining of exposed intima of the everted tissue |
US6241742B1 (en) | 1996-09-16 | 2001-06-05 | Origin Medsystems, Inc. | Means and method for performing an anastomosis |
US6884251B2 (en) | 1996-09-16 | 2005-04-26 | Origin Medsystems, Inc. | Apparatus and method for performing an anastomosis |
US6488692B1 (en) | 1996-09-16 | 2002-12-03 | Origin Medsystems, Inc. | Access and cannulation device and method for rapidly placing same and for rapidly closing same in minimally invasive surgery |
US6190397B1 (en) | 1996-09-16 | 2001-02-20 | Origin Medsystems, Inc. | Means and method for performing an anastomosis |
US6254617B1 (en) | 1996-09-16 | 2001-07-03 | Origin Medsystems, Inc. | Means and method for performing an anastomosis |
US6019788A (en) * | 1996-11-08 | 2000-02-01 | Gore Enterprise Holdings, Inc. | Vascular shunt graft and junction for same |
US6582409B1 (en) * | 1997-02-07 | 2003-06-24 | Graftcath, Inc. | Hemodialysis and vascular access systems |
USRE44639E1 (en) | 1997-02-07 | 2013-12-10 | Hemosphere, Inc. | Hemodialysis and vascular access system |
USRE41448E1 (en) * | 1997-02-07 | 2010-07-20 | Hemosphere, Inc. | Squitieri hemodialysis and vascular access systems |
US7708769B1 (en) | 1997-03-13 | 2010-05-04 | United States Surgical Corporation | Graft attachment assembly |
US6589278B1 (en) | 1997-05-17 | 2003-07-08 | Impra, Inc. | Vascular prosthesis |
US9445886B2 (en) | 1997-05-17 | 2016-09-20 | Bard Peripheral Vascular, Inc. | Vascular prosthesis |
USRE45426E1 (en) | 1997-05-21 | 2015-03-17 | Ethicon, Inc. | Surgical methods using one-way suture |
US6030395A (en) * | 1997-05-22 | 2000-02-29 | Kensey Nash Corporation | Anastomosis connection system |
US6402767B1 (en) | 1997-05-22 | 2002-06-11 | Kensey Nash Corporation | Anastomosis connection system and method of use |
US6036705A (en) * | 1997-05-22 | 2000-03-14 | Kensey Nash Corporation | Anastomosis connection system and method of use |
US6056762A (en) * | 1997-05-22 | 2000-05-02 | Kensey Nash Corporation | Anastomosis system and method of use |
US20010003795A1 (en) * | 1997-07-22 | 2001-06-14 | Mitta Suresh | Catheter system and method for posterior epicardial revascularization and intracardiac surgery on a beating heart |
US20050245946A1 (en) * | 1997-09-04 | 2005-11-03 | Nash John E | Surgical connector systems and methods of use |
US6017352A (en) * | 1997-09-04 | 2000-01-25 | Kensey Nash Corporation | Systems for intravascular procedures and methods of use |
US20070293881A1 (en) * | 1997-09-04 | 2007-12-20 | Nash John E | Surgical connector systems and methods of use |
US7695483B2 (en) | 1997-09-04 | 2010-04-13 | Kensey Nash Corporation | Surgical connector systems and methods of use |
US5922022A (en) * | 1997-09-04 | 1999-07-13 | Kensey Nash Corporation | Bifurcated connector system for coronary bypass grafts and methods of use |
US8377080B2 (en) | 1997-09-04 | 2013-02-19 | Kensey Nash Corporation | Surgical connector systems and methods of use |
US6063114A (en) * | 1997-09-04 | 2000-05-16 | Kensey Nash Corporation | Connector system for vessels, ducts, lumens or hollow organs and methods of use |
US6923820B1 (en) | 1997-09-04 | 2005-08-02 | Kensey Nash Corporation | Surgical connector systems and methods of use |
US7264624B2 (en) | 1997-09-04 | 2007-09-04 | Kensey Nash Corporation | Surgical connector systems and methods of use |
US20100217290A1 (en) * | 1997-09-04 | 2010-08-26 | Nash John E | Surgical connector systems and methods of use |
US6350280B1 (en) | 1997-09-04 | 2002-02-26 | Kensey Nash Corporation | Surgical connector systems and methods of use |
US7476199B2 (en) | 1997-09-17 | 2009-01-13 | Maquet Cardiovascular, Llc. | Device to permit offpump beating heart coronary bypass surgery |
US7195591B2 (en) | 1997-09-17 | 2007-03-27 | Origin Medsystems, Inc. | Device to permit offpump beating heart coronary bypass surgery |
US7377895B2 (en) | 1997-09-17 | 2008-05-27 | Origin Medsystems, Inc. | Device to permit offpump beating heart coronary bypass surgery |
US7476196B2 (en) | 1997-09-17 | 2009-01-13 | Maquet Cardiovascular, Llc | Device to permit offpump beating heart coronary bypass surgery |
US8753266B2 (en) | 1997-09-17 | 2014-06-17 | Maquet Cardiovascular Llc | Device to permit offpump beating heart coronary bypass surgery |
US6705988B2 (en) | 1997-09-17 | 2004-03-16 | Origin Medsystems, Inc. | Device to permit offpump beating heart coronary bypass surgery |
US8162817B2 (en) | 1997-09-17 | 2012-04-24 | Maquet Cardiovascular Llc | Device to permit offpump beating heart coronary bypass surgery |
US6969349B1 (en) | 1997-09-17 | 2005-11-29 | Origin Medsystem, Inc. | Device to permit offpump beating heart coronary bypass surgery |
US20070179344A1 (en) * | 1997-09-17 | 2007-08-02 | Spence Paul A | Device to permit offpump beating heart coronary bypass surgery |
US8317695B2 (en) | 1997-09-17 | 2012-11-27 | Maquet Cardiovascular Llc | Device to permit offpump beating heart coronary bypass surgery |
US20020065451A1 (en) * | 1997-09-17 | 2002-05-30 | Spence Paul A. | Device to permit offpump beating heart coronary bypass surgery |
US7404792B2 (en) | 1997-09-17 | 2008-07-29 | Origin Medsystems, Inc. | Device to permit offpump beating heart coronary bypass surgery |
US6743170B1 (en) | 1997-09-17 | 2004-06-01 | Cardiothoracic Systems, Inc. | Device to permit offpump beating heart coronary bypass surgery |
WO1999033403A1 (en) | 1997-12-31 | 1999-07-08 | Kensey Nash Corporation | Bifurcated connector system for coronary bypass grafts |
US6007576A (en) * | 1998-02-06 | 1999-12-28 | Mcclellan; Scott B. | End to side anastomic implant |
US6110188A (en) * | 1998-03-09 | 2000-08-29 | Corvascular, Inc. | Anastomosis method |
US20010001827A1 (en) * | 1998-03-09 | 2001-05-24 | Chapman Troy J. | Anastomosis device and method |
US6241741B1 (en) | 1998-03-09 | 2001-06-05 | Corvascular Surgical Systems, Inc. | Anastomosis device and method |
US7105002B2 (en) | 1998-03-09 | 2006-09-12 | Ethicon, Inc. | Anastomosis device and method |
US6176864B1 (en) * | 1998-03-09 | 2001-01-23 | Corvascular, Inc. | Anastomosis device and method |
US6743243B1 (en) | 1998-03-20 | 2004-06-01 | Sumit Roy | Support device for endoscopic suturless anastomosis |
USRE37107E1 (en) * | 1998-06-10 | 2001-03-20 | Surgical Innovations Llc | Device and method for the surgical anastomasis of tubular structures |
US5868765A (en) * | 1998-06-10 | 1999-02-09 | Surgical Innovations, Llc | Device and method for the surgical anastomasis of tubular structures |
WO1999063894A1 (en) * | 1998-06-10 | 1999-12-16 | Surgical Innovations, Llc | Device and method for anastomosis tubular structures |
US20040210302A1 (en) * | 1998-12-08 | 2004-10-21 | Bard Peripheral Vascular | Flanged graft for end-to-side anastomosis |
US7553316B2 (en) | 1998-12-08 | 2009-06-30 | Bard Peripheral Vascular, Inc. | Flanged graft for end-to-side anastomosis |
US6746480B2 (en) * | 1998-12-08 | 2004-06-08 | Bard Peripheral Vascular, Inc. | Flanged graft for end-to-side anastomosis |
US6315752B1 (en) | 1999-03-26 | 2001-11-13 | Scimed Life Systems, Inc. | Implantable bypass device |
US20040092799A1 (en) * | 1999-05-04 | 2004-05-13 | Hu Lawrence W. | Method and apparatus for creating a working opening through an incision |
US6685632B1 (en) | 1999-05-04 | 2004-02-03 | Cardiothoracic Systems, Inc. | Surgical instruments for accessing and stabilizing a localized portion of a beating heart |
US9498198B2 (en) | 1999-05-04 | 2016-11-22 | Maquet Cardiovascular, Llc | Surgical instruments for accessing and stabilizing a localized portion of a beating heart |
US20040143168A1 (en) * | 1999-05-04 | 2004-07-22 | Hu Lawrence W. | Surgical instruments for accessing and stabilizing a localized portion of a beating heart |
US7238155B2 (en) | 1999-05-04 | 2007-07-03 | Cardiothoracic Systems, Inc. | Method and apparatus for creating a working opening through an incision |
US6926724B1 (en) * | 1999-05-04 | 2005-08-09 | City Of Hope | Visceral anastomotic device and method of using same |
US6283912B1 (en) | 1999-05-04 | 2001-09-04 | Cardiothoracic Systems, Inc. | Surgical retractor platform blade apparatus |
US6626830B1 (en) | 1999-05-04 | 2003-09-30 | Cardiothoracic Systems, Inc. | Methods and devices for improved tissue stabilization |
US7220228B2 (en) | 1999-05-04 | 2007-05-22 | Cardiothoracic System, Inc. | Surgical retractor blade and system |
US6331158B1 (en) | 1999-05-04 | 2001-12-18 | Cardiothoracic Systems, Inc. | Surgical retractor apparatus for operating on the heart through an incision |
US6231506B1 (en) | 1999-05-04 | 2001-05-15 | Cardiothoracic Systems, Inc. | Method and apparatus for creating a working opening through an incision |
US7736307B2 (en) | 1999-05-04 | 2010-06-15 | Maquet Cardiovascular Llc | Surgical instruments for accessing and stabilizing a localized portion of a beating heart |
US6652454B2 (en) | 1999-05-04 | 2003-11-25 | Lawrence W. Hu | Method and apparatus for creating a working opening through an incision |
US20050261761A1 (en) * | 1999-05-04 | 2005-11-24 | City Of Hope | Visceral anastomotic device and method of using same |
US9814869B1 (en) | 1999-06-15 | 2017-11-14 | C.R. Bard, Inc. | Graft-catheter vascular access system |
US9993633B2 (en) | 1999-06-15 | 2018-06-12 | C. R. Bard, Inc. | Graft-catheter vascular access system |
US7503891B2 (en) | 1999-08-03 | 2009-03-17 | Maquet Cardiovascular, Llc | Tissue stabilizer and methods of use |
US6511416B1 (en) | 1999-08-03 | 2003-01-28 | Cardiothoracic Systems, Inc. | Tissue stabilizer and methods of use |
US6406424B1 (en) | 1999-09-16 | 2002-06-18 | Williamson, Iv Warren P. | Tissue stabilizer having an articulating lift element |
US7326177B2 (en) | 1999-09-16 | 2008-02-05 | Cardiothoracic Systems, Inc. | Tissue stabilizer having an articulating lift element |
US20030130671A1 (en) * | 1999-11-23 | 2003-07-10 | Duhaylongsod Francis G. | Anastomosis device and method |
WO2002013675A2 (en) * | 2000-08-10 | 2002-02-21 | Dialysis Access Solutions, Inc. | Distally narrowed vascular grafts |
WO2002013675A3 (en) * | 2000-08-10 | 2002-06-13 | Dialysis Access Solutions Inc | Distally narrowed vascular grafts |
US6585762B1 (en) | 2000-08-10 | 2003-07-01 | Paul Stanish | Arteriovenous grafts and methods of implanting the same |
US20050004584A1 (en) * | 2000-09-25 | 2005-01-06 | Cohesion Technologies, Inc. | Resorbable anastomosis stents and plugs and their use in patients |
US20050165428A1 (en) * | 2000-09-25 | 2005-07-28 | Franco Kenneth L. | Absorable surgical structure |
US6758808B2 (en) | 2001-01-24 | 2004-07-06 | Cardiothoracic System, Inc. | Surgical instruments for stabilizing a localized portion of a beating heart |
US6890338B1 (en) | 2001-02-27 | 2005-05-10 | Origin Medsystems, Inc. | Method and apparatus for performing anastomosis using ring having tines with weak sections |
US20050021060A1 (en) * | 2001-02-27 | 2005-01-27 | Davis John W. | Device, tools and methods for performing anastomosis |
US20040220643A1 (en) * | 2001-04-27 | 2004-11-04 | Medtronic, Inc. | Implantable medical device with rechargeable thin-film microbattery power source |
US7056331B2 (en) | 2001-06-29 | 2006-06-06 | Quill Medical, Inc. | Suture method |
US8747437B2 (en) | 2001-06-29 | 2014-06-10 | Ethicon, Inc. | Continuous stitch wound closure utilizing one-way suture |
US20060111734A1 (en) * | 2001-06-29 | 2006-05-25 | Andrew Kaplan | Suture method |
US6599310B2 (en) | 2001-06-29 | 2003-07-29 | Quill Medical, Inc. | Suture method |
US8764776B2 (en) | 2001-06-29 | 2014-07-01 | Ethicon, Inc. | Anastomosis method using self-retaining sutures |
US20060111742A1 (en) * | 2001-06-29 | 2006-05-25 | Andrew Kaplan | Suture method |
US8764796B2 (en) | 2001-06-29 | 2014-07-01 | Ethicon, Inc. | Suture method |
US20070208377A1 (en) * | 2001-06-29 | 2007-09-06 | Andrew Kaplan | Suture Method |
US7857829B2 (en) | 2001-06-29 | 2010-12-28 | Quill Medical, Inc. | Suture method |
US8777989B2 (en) | 2001-06-29 | 2014-07-15 | Ethicon, Inc. | Subcutaneous sinusoidal wound closure utilizing one-way suture |
US8777988B2 (en) | 2001-06-29 | 2014-07-15 | Ethicon, Inc. | Methods for using self-retaining sutures in endoscopic procedures |
US20040073282A1 (en) * | 2001-08-06 | 2004-04-15 | Paul Stanish | Distally-narrowed vascular grafts and methods of using same for making artery-to-vein and artery-to-artery connections |
US7996968B2 (en) | 2001-08-31 | 2011-08-16 | Quill Medical, Inc. | Automated method for cutting tissue retainers on a suture |
US7996967B2 (en) | 2001-08-31 | 2011-08-16 | Quill Medical, Inc. | System for variable-angle cutting of a suture to create tissue retainers of a desired shape and size |
US20070187861A1 (en) * | 2001-08-31 | 2007-08-16 | Quill Medical, Inc. | Method of Forming Barbs on a Suture and Apparatus for Performing Same |
US8028388B2 (en) | 2001-08-31 | 2011-10-04 | Quill Medical, Inc. | System for cutting a suture to create tissue retainers of a desired shape and size |
US8028387B2 (en) | 2001-08-31 | 2011-10-04 | Quill Medical, Inc. | System for supporting and cutting suture thread to create tissue retainers thereon |
US8020263B2 (en) | 2001-08-31 | 2011-09-20 | Quill Medical, Inc. | Automated system for cutting tissue retainers on a suture |
US8015678B2 (en) | 2001-08-31 | 2011-09-13 | Quill Medical, Inc. | Method for cutting a suture to create tissue retainers of a desired shape and size |
US8011072B2 (en) | 2001-08-31 | 2011-09-06 | Quill Medical, Inc. | Method for variable-angle cutting of a suture to create tissue retainers of a desired shape and size |
US7225512B2 (en) | 2001-08-31 | 2007-06-05 | Quill Medical, Inc. | Method of forming barbs on a suture and apparatus for performing same |
US8926659B2 (en) | 2001-08-31 | 2015-01-06 | Ethicon, Inc. | Barbed suture created having barbs defined by variable-angle cut |
US20040237736A1 (en) * | 2001-08-31 | 2004-12-02 | Genova Perry A. | Method of forming barbs on a suture and apparatus for performing same |
US7913365B2 (en) | 2001-08-31 | 2011-03-29 | Quill Medical, Inc. | Method of forming barbs on a suture and apparatus for performing same |
US20030114923A1 (en) * | 2001-11-14 | 2003-06-19 | Swanick Thomas M. | Graft and method of making |
US8303610B2 (en) | 2002-01-25 | 2012-11-06 | Erbe Elektromedizin Gmbh | Device for the production of anastomoses between hollow organs |
WO2003061487A1 (en) * | 2002-01-25 | 2003-07-31 | Erbe Elektromedizin Gmbh | Device for the production of anastomoses between hollow organs |
US20050055022A1 (en) * | 2002-01-25 | 2005-03-10 | Heinrich Schubert | Device for the production of anastomoses between hollow organs |
US20060084941A1 (en) * | 2002-04-23 | 2006-04-20 | Medtronic, Inc. | Implantable medical connector for medical tubing with anchoring features |
US20060084940A1 (en) * | 2002-04-23 | 2006-04-20 | Medtronic, Inc. | Implantable medical connector for medical tubing with anchoring features |
US6997919B2 (en) | 2002-04-23 | 2006-02-14 | Medtronic, Inc. | Implantable medical connector for medical tubing with anchoring features |
WO2003090840A1 (en) * | 2002-04-23 | 2003-11-06 | Medtronic, Inc. | Implantable medical catheter connector for medical tubing with anchoring features |
US8734486B2 (en) | 2002-08-09 | 2014-05-27 | Ethicon, Inc. | Multiple suture thread configuration with an intermediate connector |
US20040030354A1 (en) * | 2002-08-09 | 2004-02-12 | Leung Jeffrey C. | Suture anchor and method |
US8083770B2 (en) | 2002-08-09 | 2011-12-27 | Quill Medical, Inc. | Suture anchor and method |
US8690914B2 (en) | 2002-08-09 | 2014-04-08 | Ethicon, Inc. | Suture with an intermediate barbed body |
US8652170B2 (en) | 2002-08-09 | 2014-02-18 | Ethicon, Inc. | Double ended barbed suture with an intermediate body |
US8679158B2 (en) | 2002-08-09 | 2014-03-25 | Ethicon, Inc. | Multiple suture thread configuration with an intermediate connector |
US20040254595A1 (en) * | 2002-09-12 | 2004-12-16 | Thierry Richard | Prosthetic vascular graft connector |
US20040054405A1 (en) * | 2002-09-12 | 2004-03-18 | Edrich Health Technologies, Inc., A Corporation Of The State Of Delaware | Prosthetic vascular graft connector |
US6929648B2 (en) | 2002-09-12 | 2005-08-16 | Edrich Vascular Devices, Inc. | Prosthetic vascular graft connector |
US6896688B2 (en) | 2002-09-12 | 2005-05-24 | Edrich Health Technologies, Inc. | Prosthetic vascular graft connector |
US8721681B2 (en) | 2002-09-30 | 2014-05-13 | Ethicon, Inc. | Barbed suture in combination with surgical needle |
US20100298876A1 (en) * | 2002-09-30 | 2010-11-25 | Quill Medical, Inc. | Self-retaining sutures having effective holding strength and tensile strength |
US9248580B2 (en) | 2002-09-30 | 2016-02-02 | Ethicon, Inc. | Barb configurations for barbed sutures |
US8795332B2 (en) | 2002-09-30 | 2014-08-05 | Ethicon, Inc. | Barbed sutures |
US8821540B2 (en) | 2002-09-30 | 2014-09-02 | Ethicon, Inc. | Self-retaining sutures having effective holding strength and tensile strength |
US8734485B2 (en) | 2002-09-30 | 2014-05-27 | Ethicon, Inc. | Sutures with barbs that overlap and cover projections |
US8852232B2 (en) | 2002-09-30 | 2014-10-07 | Ethicon, Inc. | Self-retaining sutures having effective holding strength and tensile strength |
US20040088003A1 (en) * | 2002-09-30 | 2004-05-06 | Leung Jeffrey C. | Barbed suture in combination with surgical needle |
US7931590B2 (en) | 2002-10-29 | 2011-04-26 | Maquet Cardiovascular Llc | Tissue stabilizer and methods of using the same |
US20040153104A1 (en) * | 2002-11-05 | 2004-08-05 | Damage Control Surgical Technologies, Inc. | Method and device for temporary emergency vessel anastomoses |
US7335215B2 (en) | 2002-11-05 | 2008-02-26 | Damage Control Surgical Technologies, Inc. | Method and device for temporary emergency vessel anastomoses |
WO2004041074A3 (en) * | 2002-11-05 | 2005-08-11 | Damage Control Surgical Techno | Method and device for temporary emergency vessel anastomoses |
WO2004041074A2 (en) * | 2002-11-05 | 2004-05-21 | Damage Control Surgical Technologies, Inc. | Method and device for temporary emergency vessel anastomoses |
US8032996B2 (en) | 2003-05-13 | 2011-10-11 | Quill Medical, Inc. | Apparatus for forming barbs on a suture |
US7624487B2 (en) | 2003-05-13 | 2009-12-01 | Quill Medical, Inc. | Apparatus and method for forming barbs on a suture |
US8641598B2 (en) | 2003-07-08 | 2014-02-04 | Maquet Cardiovascular Llc | Organ manipulator apparatus |
US7479104B2 (en) | 2003-07-08 | 2009-01-20 | Maquet Cardiovascular, Llc | Organ manipulator apparatus |
US9402608B2 (en) | 2003-07-08 | 2016-08-02 | Maquet Cardiovascular Llc | Organ manipulator apparatus |
US10383612B2 (en) | 2003-07-08 | 2019-08-20 | Maquet Cardiovascular Llc | Organ manipulator apparatus |
US20110060264A1 (en) * | 2003-10-08 | 2011-03-10 | Hemosphere Inc. | Device and method for vascular access |
US20060064159A1 (en) * | 2003-10-08 | 2006-03-23 | Porter Christopher H | Device and method for vascular access |
US8690815B2 (en) * | 2003-10-08 | 2014-04-08 | Hemosphere, Inc. | Device and method for vascular access |
USRE47154E1 (en) * | 2003-10-08 | 2018-12-11 | Merit Medical Systems, Inc. | Device and method for vascular access |
US20050137614A1 (en) * | 2003-10-08 | 2005-06-23 | Porter Christopher H. | System and method for connecting implanted conduits |
US7762977B2 (en) | 2003-10-08 | 2010-07-27 | Hemosphere, Inc. | Device and method for vascular access |
GB2407773A (en) * | 2003-11-06 | 2005-05-11 | Martin Lister | Connector for blood vessels |
GB2407773B (en) * | 2003-11-06 | 2007-09-26 | Lister Martin | Vein/artery connector |
US7179224B2 (en) | 2003-12-30 | 2007-02-20 | Cardiothoracic Systems, Inc. | Organ manipulator and positioner and methods of using the same |
US10548592B2 (en) | 2004-05-14 | 2020-02-04 | Ethicon, Inc. | Suture methods and devices |
US8721664B2 (en) | 2004-05-14 | 2014-05-13 | Ethicon, Inc. | Suture methods and devices |
US20100298871A1 (en) * | 2004-05-14 | 2010-11-25 | Quill Medical, Inc. | Self-retaining wound closure device including an anchoring loop |
US10779815B2 (en) | 2004-05-14 | 2020-09-22 | Ethicon, Inc. | Suture methods and devices |
US11723654B2 (en) | 2004-05-14 | 2023-08-15 | Ethicon, Inc. | Suture methods and devices |
WO2006026687A3 (en) * | 2004-08-31 | 2007-05-31 | Graftcath Inc | Improved device and method for vascular access |
US20150238192A1 (en) * | 2004-10-15 | 2015-08-27 | Covidien Lp | Seal element for anastomosis |
US10456139B2 (en) | 2004-10-15 | 2019-10-29 | Covidien Lp | Seal element for anastomosis |
US9737304B2 (en) * | 2004-10-15 | 2017-08-22 | Covidien Lp | Seal element for anastomosis |
US8083664B2 (en) | 2005-05-25 | 2011-12-27 | Maquet Cardiovascular Llc | Surgical stabilizers and methods for use in reduced-access surgical sites |
US10172702B2 (en) | 2005-07-01 | 2019-01-08 | C. R. Bard, Inc. | Trimming apparatus |
US8709069B2 (en) | 2005-07-01 | 2014-04-29 | C. R. Bard, Inc. | Flanged graft with trim lines |
US20070005128A1 (en) * | 2005-07-01 | 2007-01-04 | C. R. Bard, Inc. | Flanged graft with trim lines |
US9532865B2 (en) | 2005-07-01 | 2017-01-03 | C.R. Bard, Inc. | Trimming apparatus |
US20070167901A1 (en) * | 2005-11-17 | 2007-07-19 | Herrig Judson A | Self-sealing residual compressive stress graft for dialysis |
US9375215B2 (en) | 2006-01-20 | 2016-06-28 | W. L. Gore & Associates, Inc. | Device for rapid repair of body conduits |
US20110230951A1 (en) * | 2006-01-20 | 2011-09-22 | Cully Edward H | Device for rapid repair of body conduits |
US20070198077A1 (en) * | 2006-01-20 | 2007-08-23 | Cully Edward H | Device for rapid repair of body conduits |
US10357352B2 (en) | 2006-01-20 | 2019-07-23 | W. L. Gore & Associates, Inc. | Device for rapid repair of body conduits |
US9381018B2 (en) | 2006-01-20 | 2016-07-05 | W. L. Gore & Associates, Inc. | Device for rapid repair of body conduits |
US8313013B2 (en) | 2006-04-06 | 2012-11-20 | Synovis Life Technologies, Inc. | Method and assembly for anastomosis |
US20070239180A1 (en) * | 2006-04-06 | 2007-10-11 | Synovis Life Technologies, Inc. | Method and assembly for anastomosis |
US8197499B2 (en) * | 2006-06-21 | 2012-06-12 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for joining non-conjoined lumens |
US20090187199A1 (en) * | 2006-06-21 | 2009-07-23 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for joining non-conjoined lumens |
US8608760B2 (en) * | 2006-06-21 | 2013-12-17 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for joining non-conjoined lumens |
US20080045985A1 (en) * | 2006-06-21 | 2008-02-21 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for joining non-conjoined lumens |
US8216259B2 (en) * | 2006-06-21 | 2012-07-10 | The Board Of Trustees Of The Leland Stanford Jr. University | Compositions and methods for joining non-conjoined lumens |
US20080262519A1 (en) * | 2006-06-21 | 2008-10-23 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for joining non-conjoined lumens |
US8793863B2 (en) | 2007-04-13 | 2014-08-05 | Ethicon, Inc. | Method and apparatus for forming retainers on a suture |
US8915943B2 (en) | 2007-04-13 | 2014-12-23 | Ethicon, Inc. | Self-retaining systems for surgical procedures |
US8777987B2 (en) | 2007-09-27 | 2014-07-15 | Ethicon, Inc. | Self-retaining sutures including tissue retainers having improved strength |
US9498893B2 (en) | 2007-09-27 | 2016-11-22 | Ethicon, Inc. | Self-retaining sutures including tissue retainers having improved strength |
US8771313B2 (en) | 2007-12-19 | 2014-07-08 | Ethicon, Inc. | Self-retaining sutures with heat-contact mediated retainers |
US8916077B1 (en) | 2007-12-19 | 2014-12-23 | Ethicon, Inc. | Self-retaining sutures with retainers formed from molten material |
US8118834B1 (en) | 2007-12-20 | 2012-02-21 | Angiotech Pharmaceuticals, Inc. | Composite self-retaining sutures and method |
US9044225B1 (en) | 2007-12-20 | 2015-06-02 | Ethicon, Inc. | Composite self-retaining sutures and method |
US20100280598A1 (en) * | 2007-12-27 | 2010-11-04 | C.R. Bard, Inc. | Vascular graft prosthesis having a reinforced margin for enhanced anastomosis |
US9694165B2 (en) * | 2008-01-28 | 2017-07-04 | Peter Mats Forsell | Implantable drainage device |
US20150157836A1 (en) * | 2008-01-28 | 2015-06-11 | Peter Mats Forsell | Implantable drainage device |
US8875607B2 (en) | 2008-01-30 | 2014-11-04 | Ethicon, Inc. | Apparatus and method for forming self-retaining sutures |
US8615856B1 (en) | 2008-01-30 | 2013-12-31 | Ethicon, Inc. | Apparatus and method for forming self-retaining sutures |
US9125647B2 (en) | 2008-02-21 | 2015-09-08 | Ethicon, Inc. | Method and apparatus for elevating retainers on self-retaining sutures |
US8460338B2 (en) | 2008-02-25 | 2013-06-11 | Ethicon, Inc. | Self-retainers with supporting structures on a suture |
US8216273B1 (en) | 2008-02-25 | 2012-07-10 | Ethicon, Inc. | Self-retainers with supporting structures on a suture |
US8641732B1 (en) | 2008-02-26 | 2014-02-04 | Ethicon, Inc. | Self-retaining suture with variable dimension filament and method |
US8079973B2 (en) | 2008-03-05 | 2011-12-20 | Hemosphere Inc. | Vascular access system |
US10792413B2 (en) | 2008-03-05 | 2020-10-06 | Merit Medical Systems, Inc. | Implantable and removable customizable body conduit |
US8876865B2 (en) | 2008-04-15 | 2014-11-04 | Ethicon, Inc. | Self-retaining sutures with bi-directional retainers or uni-directional retainers |
US8211129B2 (en) | 2008-05-06 | 2012-07-03 | Unique Surgical Innovations Llc | Method for anastomosis surgery using zip-ties |
US20090281560A1 (en) * | 2008-05-06 | 2009-11-12 | Wexner Steven D | Method for anastomosis surgery using zip-ties |
US8961560B2 (en) | 2008-05-16 | 2015-02-24 | Ethicon, Inc. | Bidirectional self-retaining sutures with laser-marked and/or non-laser marked indicia and methods |
WO2010030707A1 (en) * | 2008-09-10 | 2010-03-18 | Unique Surgical Innovations, Llc | Surgical string applicator for anastomosis surgery and method of use |
US10441270B2 (en) | 2008-11-03 | 2019-10-15 | Ethicon, Inc. | Length of self-retaining suture and method and device for using the same |
US8932328B2 (en) | 2008-11-03 | 2015-01-13 | Ethicon, Inc. | Length of self-retaining suture and method and device for using the same |
US11234689B2 (en) | 2008-11-03 | 2022-02-01 | Ethicon, Inc. | Length of self-retaining suture and method and device for using the same |
US20100153335A1 (en) * | 2008-12-12 | 2010-06-17 | Microsoft Corporation | Synchronizing multiple classes with disparate schemas in the same collection |
US20140155804A1 (en) * | 2009-07-07 | 2014-06-05 | Marwan Tabbara | Surgical devices and kits |
US20110009802A1 (en) * | 2009-07-07 | 2011-01-13 | Marwan Tabbara | Surgical Methods, Devices, and Kits |
US8591451B2 (en) | 2009-07-07 | 2013-11-26 | Marwan Tabbara | Surgical methods, devices, and kits |
US11241231B2 (en) | 2009-09-14 | 2022-02-08 | Circulite, Inc. | Endovascular anastomotic connector device, delivery system, and methods of delivery and use |
US9050419B2 (en) | 2009-09-14 | 2015-06-09 | Circulite, Inc. | Endovascular anastomotic connector device, delivery system, and methods of delivery and use |
US20110066170A1 (en) * | 2009-09-14 | 2011-03-17 | Circulite, Inc. | Endovascular anastomotic connector device, delivery system, and methods of delivery and use |
US8333727B2 (en) | 2009-10-08 | 2012-12-18 | Circulite, Inc. | Two piece endovascular anastomotic connector |
US20110087063A1 (en) * | 2009-10-08 | 2011-04-14 | Circulite, Inc. | Two piece endovascular anastomotic connector |
US9662434B2 (en) | 2010-02-26 | 2017-05-30 | Maquet Cardiovascular Llc | Blower instrument, apparatus and methods of using |
US9022998B2 (en) | 2010-02-26 | 2015-05-05 | Maquet Cardiovascular Llc | Blower instrument, apparatus and methods of using |
US10952721B2 (en) | 2010-05-04 | 2021-03-23 | Ethicon, Inc. | Laser cutting system and methods for creating self-retaining sutures |
US10420546B2 (en) | 2010-05-04 | 2019-09-24 | Ethicon, Inc. | Self-retaining systems having laser-cut retainers |
US11234692B2 (en) | 2010-05-04 | 2022-02-01 | Cilag Gmbh International | Self-retaining system having laser-cut retainers |
US9955962B2 (en) | 2010-06-11 | 2018-05-01 | Ethicon, Inc. | Suture delivery tools for endoscopic and robot-assisted surgery and methods |
US9655605B2 (en) | 2010-06-14 | 2017-05-23 | Maquet Cardiovascular Llc | Surgical instruments, systems and methods of use |
US11284872B2 (en) | 2010-06-14 | 2022-03-29 | Maquet Cardiovascular Llc | Surgical instruments, systems and methods of use |
US10398422B2 (en) | 2010-06-14 | 2019-09-03 | Maquet Cardiovascular Llc | Surgical instruments, systems and methods of use |
JP2013534444A (en) * | 2010-07-09 | 2013-09-05 | ハイライフ エスエーエス | Transcatheter atrioventricular valve prosthesis |
US11007296B2 (en) | 2010-11-03 | 2021-05-18 | Ethicon, Inc. | Drug-eluting self-retaining sutures and methods relating thereto |
US9675341B2 (en) | 2010-11-09 | 2017-06-13 | Ethicon Inc. | Emergency self-retaining sutures and packaging |
US9155556B2 (en) * | 2010-12-06 | 2015-10-13 | Circ Med Tech Ltd. | Support element for circumcision and system comprising the same |
US20140309654A1 (en) * | 2010-12-06 | 2014-10-16 | Circ Medtech Ltd. | Support element for circumcision and system comprising the same |
US10492780B2 (en) | 2011-03-23 | 2019-12-03 | Ethicon, Inc. | Self-retaining variable loop sutures |
US11690614B2 (en) | 2011-03-23 | 2023-07-04 | Ethicon, Inc. | Self-retaining variable loop sutures |
US20140276326A1 (en) * | 2011-05-16 | 2014-09-18 | Berlin Heart Gmbh | Connection system for creating a connection channel for bodily fluids |
US9744286B2 (en) * | 2011-05-16 | 2017-08-29 | Berlin Heart Gmbh | Connection system for creating a connection channel for bodily fluids |
US10188384B2 (en) | 2011-06-06 | 2019-01-29 | Ethicon, Inc. | Methods and devices for soft palate tissue elevation procedures |
US10632296B2 (en) | 2011-09-06 | 2020-04-28 | Merit Medical Systems, Inc. | Vascular access system with connector |
US10213590B2 (en) | 2011-09-06 | 2019-02-26 | Merit Medical Systems, Inc. | Vascular access system with connector |
US11185676B2 (en) | 2011-09-06 | 2021-11-30 | Merit Medical Systems, Inc. | Vascular access system with connector |
WO2013185484A1 (en) * | 2012-06-14 | 2013-12-19 | Min Yike | Suture-less wound closure device for lumen within human body |
EP3076879B1 (en) * | 2013-12-06 | 2019-05-01 | W. L. Gore & Associates, Inc. | Anastomotic connector |
CN105939676A (en) * | 2013-12-06 | 2016-09-14 | W·L·戈尔及同仁股份有限公司 | Anastomotic connectors |
CN105939676B (en) * | 2013-12-06 | 2020-05-19 | W·L·戈尔及同仁股份有限公司 | Anastomotic connector |
US9974543B2 (en) * | 2013-12-06 | 2018-05-22 | W. L. Gore & Associates, Inc. | Anastomotic connectors |
US20150157324A1 (en) * | 2013-12-06 | 2015-06-11 | W. L. Gore & Associates, Inc. | Anastomotic connectors |
US10682453B2 (en) | 2013-12-20 | 2020-06-16 | Merit Medical Systems, Inc. | Vascular access system with reinforcement member |
RU2569604C1 (en) * | 2014-07-25 | 2015-11-27 | Общество с ограниченной ответственностью "Научно-технический центр "Мепотекс" | Blood, blood substitute or infusion solution line |
US20190038288A1 (en) * | 2016-02-05 | 2019-02-07 | Chu De Nice | Anastomotic connector |
CN106422049A (en) * | 2016-10-31 | 2017-02-22 | 黄剑 | Bridging stent based on temporary blood circulation restoring application and processing method thereof |
US11413043B2 (en) | 2016-11-10 | 2022-08-16 | Merit Medical Systems, Inc. | Anchor device for vascular anastomosis |
US11383072B2 (en) | 2017-01-12 | 2022-07-12 | Merit Medical Systems, Inc. | Methods and systems for selection and use of connectors between conduits |
US11590010B2 (en) | 2017-01-25 | 2023-02-28 | Merit Medical Systems, Inc. | Methods and systems for facilitating laminar flow between conduits |
US11026704B2 (en) | 2017-03-06 | 2021-06-08 | Merit Medical Systems, Inc. | Vascular access assembly declotting systems and methods |
US11622846B2 (en) | 2017-03-24 | 2023-04-11 | Merit Medical Systems, Inc. | Subcutaneous vascular assemblies for improving blood flow and related devices and methods |
US10925710B2 (en) | 2017-03-24 | 2021-02-23 | Merit Medical Systems, Inc. | Subcutaneous vascular assemblies for improving blood flow and related devices and methods |
US11179543B2 (en) | 2017-07-14 | 2021-11-23 | Merit Medical Systems, Inc. | Releasable conduit connectors |
US11911585B2 (en) | 2017-07-20 | 2024-02-27 | Merit Medical Systems, Inc. | Methods and systems for coupling conduits |
US11331458B2 (en) | 2017-10-31 | 2022-05-17 | Merit Medical Systems, Inc. | Subcutaneous vascular assemblies for improving blood flow and related devices and methods |
US11751876B2 (en) | 2019-05-07 | 2023-09-12 | Easyflomicro Inc. | Apparatuses for anastomosis of tubular vessels and related methods |
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