US20110213386A1 - Ophthalmic wound closure devices and methods - Google Patents
Ophthalmic wound closure devices and methods Download PDFInfo
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- US20110213386A1 US20110213386A1 US12/895,058 US89505810A US2011213386A1 US 20110213386 A1 US20110213386 A1 US 20110213386A1 US 89505810 A US89505810 A US 89505810A US 2011213386 A1 US2011213386 A1 US 2011213386A1
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- Prior art keywords
- suture
- wound
- modified
- eye
- transparent portion
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0482—Needle or suture guides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/06—Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
- A61B17/06166—Sutures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00831—Material properties
- A61B2017/00902—Material properties transparent or translucent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/06—Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
- A61B17/06166—Sutures
- A61B2017/06176—Sutures with protrusions, e.g. barbs
Definitions
- This invention relates to wound closure devices and methods to facilitate healing after an incision. Specifically, this invention relates to wound closure devices and methods for use in conjunction with ophthalmic surgery.
- the small incision, or wound leaks after the surgical instrument is removed from the incision.
- One common procedure to reduce or stop leakage is to suture the incision. Knots tied in common suturing can be uncomfortable for the patient, and can be difficult and tedious for the surgeon. As with any difficult procedure there is some degree of risk to the patient. It can also be difficult to see where the wound is due to the small size of the wound.
- What is needed is a device that aids in visualization of ophthalmic wounds. What is also needed is a device an method to reduce leakage through incisions following vitreous surgery that is easier, and more reliable. What is also needed is a device an method to reduce risk to the patient.
- FIG. 1A shows a portion of an ophthalmic procedure according to an embodiment of the invention.
- FIG. 1B shows another portion of an ophthalmic procedure according to an embodiment of the invention.
- FIG. 2 shows forming a suture according to an embodiment of the invention.
- FIG. 3A-3D show example sutures according to embodiments of the invention.
- FIG. 4 shows use of a suture according to an embodiment of the invention.
- FIG. 5 shows example sutures in place on a wound according to embodiments of the invention.
- FIG. 6 shows a visualization device according to an embodiment of the invention.
- FIG. 7 shows another visualization device according to an embodiment of the invention.
- FIG. 8 shows another visualization device according to an embodiment of the invention.
- FIG. 9 shows an example of an eye after a procedure using devices and methods according to an embodiment of the invention.
- FIG. 1A shows a portion of a procedure utilizing wound closure devices as described above.
- An eye 100 is shown.
- a cannula 110 is inserted into the eye through an incision 112 to reach a location 114 internal to the eye.
- an instrument is inserted through the cannula 110 to the location 114 in order to perform the desired procedure.
- instruments include, but are not limited to fiber optic probes, laser guides, suction/cutting tools, forceps, scissors, etc.
- FIG. 1B shows the eye 100 as shown in FIG. 1A after removal of the cannula 110 .
- a wound 120 is shown where the cannula 110 passed through the sclera into the eye. In some procedures, the wound 120 leaks, and requires closure. Various configurations of devices are illustrated below to facilitate the closure.
- FIG. 2 shows a standard round cross section suture 210 .
- one method of forming a modified suture is show.
- a wheel 212 or pair of wheels 212 , 214 are used to flatten the suture 210 and form modified suture 220 .
- a plain gut suture 210 is used.
- the flattening process provides a modified cross section that will crinkle or otherwise fold over on itself as it is drawn into tissue.
- the added friction of the modified suture provides a pullout resistance without the need for tying knots on the tissue.
- the rolling process further opens up a fiber structure within the suture and provides increased surface area to further increase friction and/or pullout resistance.
- FIG. 1 shows a standard round cross section suture 210 .
- a pattern is pressed into the suture 210 to form modifies suture 220 with the pattern pressed into the suture 210 for added pullout resistance.
- An example of a procedure using a modified suture as shown in FIG. 2 or other figures is discussed in more detail below.
- FIG. 3A shows one example of a modified suture 310 according to an embodiment of the invention.
- a number of features such as one-way barbs 312 are shown on a side of the modified suture 310 .
- FIG. 3B shows another example of a modified suture 320 according to an embodiment of the invention.
- a number of pressed features 322 such as knurls or other patterns are rolled into a surface of the suture to form a flattened, patterned modified suture 320 .
- FIG. 3C shows another example of a modified suture 330 according to an embodiment of the invention.
- a number of knots 332 are pre-tied at various spacing along a length of the suture 330 .
- FIG. 3C shows another example of a modified suture 340 according to an embodiment of the invention. A number of features such as one-way barbs 344 similar to those described in FIG. 3A are shown. A knot 342 or other protrusion is also shown at a distal end of the modified suture 340 .
- an increased friction is provided in any direction to increase pullout resistance.
- the increased friction or pullout resistance is unidirectional. Barbs 312 , 344 for example make the modified sutures 310 , 340 easy to insert in one direction, and hard to pull back, once inserted.
- a biodegradable material is used for the modified suture, such as plain gut suture.
- Other materials such as PGA, etc. may also be used.
- FIG. 4 shows an example procedure using a modified suture according to an embodiment of the invention.
- a needle 410 is shown pulling a modified suture 412 , through a location in the middle of a wound 402 in an eye 400 .
- a modified suture 412 is shown pulling a modified suture 412 , through a location in the middle of a wound 402 in an eye 400 .
- only one suture will be sufficient in many cases, the invention is not so limited.
- FIG. 5 shows examples of modified sutures such as those shown in previous Figures.
- a first suture 510 is flattened to provide increased pullout resistance, and is pulled in from one side of a wound 502 in an eye 500 to the other side. No knot is tied. Only the increased pullout resistance holds the modified suture in place. Because ophthalmic wounds in such procedures do not require large forces to hold them closed, the addition of modified pullout resistance is enough to hold the modified sutures in place without a knot. In procedures where the modified suture is placed beneath the conjunctiva, the absence of a knot is more comfortable for the patient. Further, the absence of a knot makes the procedure much simpler for the surgeon to perform.
- FIG. 5 also shows other examples of modified sutures in place.
- Modified suture 520 is shown with unidirectional barbs on side surfaces.
- Modified suture 530 shows a number of spaced knot to provide the increased pullout resistance.
- Modified suture 540 shows the unidirectional barbs in combination with a knot at a distal end. The modified suture 540 is therefore easy to install, and holds tight one in place due to the knot, and the barbs.
- FIG. 6 shows a visualization tool that is used to view a wound 602 , and can be used by itself with standard suture practices, or can be used in conjunction with modified sutures as described above.
- the Figure illustrates a glass or plastic transparent portion 610 and a handle 612 . It can often be difficult to visualize a small wound 602 due to fluids or blood present in the area, and the wound 602 itself being normally closed without any external pressure.
- pressure is put on the eye 600 in the general area of the wound 602 .
- the pressure causes the fluids and/or blood to move away from the wound 602 , and makes the wound 602 easier to visualize. Once the wound is located, the surgeon can proceed with suturing.
- FIG. 7 illustrates another example of a visualization tool that is particularly useful with the modified sutures described above.
- a transparent portion 710 is shaped thinner in the middle, for example as an hourglass shape.
- the wound 702 in the eye 700 is still visible as described in FIG. 6 above.
- a modified suture 720 can easily be inserted to close the wound 702 without having to remove the transparent portion 710 .
- a needle 722 is shown pulling in the modified suture 720 .
- An optional handle 712 is shown to better hold the transparent portion 710 and to put pressure on the eye 700 .
- FIG. 8 shows another example of a visualization tool that is particularly useful with the modified sutures described above.
- a transparent portion 810 is shown with an optional handle 812 .
- an elongated handle 812 is illustrated, any number of handle configurations are within the scope of the invention.
- a rectangular shape of the transparent portion 810 is shown, however shapes such as an hourglass shape described above, or other shapes are within the scope of the invention.
- a number of teeth 814 or other frictional protrusions are shown on surface of the transparent portion 810 that is to be adjacent to the eye.
- teeth 814 By using teeth 814 , a surgeon may grip the sclera of the eye with one hand to prevent rotation of the eye and aid in visualizing the wound simultaneously while the sutures are being placed with the other hand.
- the ability to grip the sclera is particularly useful in embodiments described above because of increased friction of the sutures in selected embodiments.
- FIG. 9 shows an example of an eye 10 days after a procedure as described above.
- Arrow 902 indicates the wound, while arrows 904 indicate sutures placed as described above.
- One advantage of wound closure devices and methods described above includes a simple and inexpensive alternative to knot tying after suturing to prevent leakage.
- Another advantage includes a biocompatible material that degrades over time to allow healing of the incision.
Abstract
A method and device for wound closure is provided. One advantage of wound closure devices and methods shown includes a simple and inexpensive modified suture with increased pullout resistance to close wounds in eyes and prevent leakage. Another advantage includes a visualization tool to aid in locating the wound on the eye.
Description
- This application claims the benefit of priority, under 35 U.S.C. Section 119(e), to Provisional Patent Application Ser. No. 61/247,818, filed Oct. 1, 2009 which is incorporated herein by reference in its entirety.
- This invention relates to wound closure devices and methods to facilitate healing after an incision. Specifically, this invention relates to wound closure devices and methods for use in conjunction with ophthalmic surgery.
- After some ophthalmic surgical procedures the small incision, or wound, leaks after the surgical instrument is removed from the incision. One common procedure to reduce or stop leakage is to suture the incision. Knots tied in common suturing can be uncomfortable for the patient, and can be difficult and tedious for the surgeon. As with any difficult procedure there is some degree of risk to the patient. It can also be difficult to see where the wound is due to the small size of the wound.
- What is needed is a device that aids in visualization of ophthalmic wounds. What is also needed is a device an method to reduce leakage through incisions following vitreous surgery that is easier, and more reliable. What is also needed is a device an method to reduce risk to the patient.
-
FIG. 1A shows a portion of an ophthalmic procedure according to an embodiment of the invention. -
FIG. 1B shows another portion of an ophthalmic procedure according to an embodiment of the invention. -
FIG. 2 shows forming a suture according to an embodiment of the invention. -
FIG. 3A-3D show example sutures according to embodiments of the invention. -
FIG. 4 shows use of a suture according to an embodiment of the invention. -
FIG. 5 shows example sutures in place on a wound according to embodiments of the invention. -
FIG. 6 shows a visualization device according to an embodiment of the invention. -
FIG. 7 shows another visualization device according to an embodiment of the invention. -
FIG. 8 shows another visualization device according to an embodiment of the invention. -
FIG. 9 shows an example of an eye after a procedure using devices and methods according to an embodiment of the invention. - In the following detailed description, reference is made to the accompanying drawings which form a part hereof, and in which is shown, by way of illustration, specific embodiments in which the invention may be practiced. In the drawings, like numerals describe substantially similar components throughout the several views. These embodiments are described in sufficient detail to enable those skilled in the art to practice the invention. Other embodiments may be utilized and structural, mechanical, logical changes, etc. may be made without departing from the scope of the present invention.
-
FIG. 1A shows a portion of a procedure utilizing wound closure devices as described above. Aneye 100 is shown. During a procedure, acannula 110 is inserted into the eye through anincision 112 to reach alocation 114 internal to the eye. Usually, an instrument is inserted through thecannula 110 to thelocation 114 in order to perform the desired procedure. Examples of instruments include, but are not limited to fiber optic probes, laser guides, suction/cutting tools, forceps, scissors, etc. - During a procedure, if the instrument (not shown) is removed from the
cannula 110, a small plastic plug is inserted to control leakage from the cannula. However at the end of the procedure, thecannula 110 is removed.FIG. 1B shows theeye 100 as shown inFIG. 1A after removal of thecannula 110. Awound 120 is shown where thecannula 110 passed through the sclera into the eye. In some procedures, thewound 120 leaks, and requires closure. Various configurations of devices are illustrated below to facilitate the closure. -
FIG. 2 shows a standard roundcross section suture 210. In the figure, one method of forming a modified suture is show. Awheel 212 or pair ofwheels suture 210 and form modifiedsuture 220. In one example, aplain gut suture 210 is used. In one example, the flattening process provides a modified cross section that will crinkle or otherwise fold over on itself as it is drawn into tissue. The added friction of the modified suture provides a pullout resistance without the need for tying knots on the tissue. In one example the rolling process further opens up a fiber structure within the suture and provides increased surface area to further increase friction and/or pullout resistance. In one example shown inFIG. 2 , a pattern is pressed into thesuture 210 to form modifiessuture 220 with the pattern pressed into thesuture 210 for added pullout resistance. An example of a procedure using a modified suture as shown inFIG. 2 or other figures is discussed in more detail below. -
FIG. 3A shows one example of a modifiedsuture 310 according to an embodiment of the invention. A number of features such as one-way barbs 312 are shown on a side of the modifiedsuture 310.FIG. 3B shows another example of a modifiedsuture 320 according to an embodiment of the invention. A number of pressedfeatures 322 such as knurls or other patterns are rolled into a surface of the suture to form a flattened, patterned modifiedsuture 320.FIG. 3C shows another example of a modifiedsuture 330 according to an embodiment of the invention. A number ofknots 332 are pre-tied at various spacing along a length of thesuture 330. The knots can be easily tied before a procedure, away from a patient, or they can be manufactured in place. Althoughknots 332 are described, other protrusions such as formed knobs, etc. may take the place ofknots 332.FIG. 3C shows another example of a modifiedsuture 340 according to an embodiment of the invention. A number of features such as one-way barbs 344 similar to those described inFIG. 3A are shown. Aknot 342 or other protrusion is also shown at a distal end of the modifiedsuture 340. - In selected examples such as modified
sutures sutures Barbs sutures - In one example a biodegradable material is used for the modified suture, such as plain gut suture. Other materials such as PGA, etc. may also be used.
-
FIG. 4 shows an example procedure using a modified suture according to an embodiment of the invention. Aneedle 410 is shown pulling a modifiedsuture 412, through a location in the middle of awound 402 in aneye 400. Although only one suture will be sufficient in many cases, the invention is not so limited. -
FIG. 5 shows examples of modified sutures such as those shown in previous Figures. Afirst suture 510 is flattened to provide increased pullout resistance, and is pulled in from one side of awound 502 in aneye 500 to the other side. No knot is tied. Only the increased pullout resistance holds the modified suture in place. Because ophthalmic wounds in such procedures do not require large forces to hold them closed, the addition of modified pullout resistance is enough to hold the modified sutures in place without a knot. In procedures where the modified suture is placed beneath the conjunctiva, the absence of a knot is more comfortable for the patient. Further, the absence of a knot makes the procedure much simpler for the surgeon to perform. -
FIG. 5 also shows other examples of modified sutures in place.Modified suture 520 is shown with unidirectional barbs on side surfaces.Modified suture 530 shows a number of spaced knot to provide the increased pullout resistance.Modified suture 540 shows the unidirectional barbs in combination with a knot at a distal end. The modifiedsuture 540 is therefore easy to install, and holds tight one in place due to the knot, and the barbs. -
FIG. 6 shows a visualization tool that is used to view awound 602, and can be used by itself with standard suture practices, or can be used in conjunction with modified sutures as described above. The Figure illustrates a glass or plastictransparent portion 610 and ahandle 612. It can often be difficult to visualize asmall wound 602 due to fluids or blood present in the area, and thewound 602 itself being normally closed without any external pressure. - Using the visualization tool, pressure is put on the
eye 600 in the general area of thewound 602. The pressure causes the fluids and/or blood to move away from thewound 602, and makes thewound 602 easier to visualize. Once the wound is located, the surgeon can proceed with suturing. -
FIG. 7 illustrates another example of a visualization tool that is particularly useful with the modified sutures described above. Atransparent portion 710 is shaped thinner in the middle, for example as an hourglass shape. Thewound 702 in theeye 700 is still visible as described inFIG. 6 above. However, due to the thinner middle of thetransparent portion 710, a modifiedsuture 720 can easily be inserted to close thewound 702 without having to remove thetransparent portion 710. Aneedle 722 is shown pulling in the modifiedsuture 720. Anoptional handle 712 is shown to better hold thetransparent portion 710 and to put pressure on theeye 700. -
FIG. 8 shows another example of a visualization tool that is particularly useful with the modified sutures described above. Atransparent portion 810 is shown with anoptional handle 812. Although anelongated handle 812 is illustrated, any number of handle configurations are within the scope of the invention. Likewise, a rectangular shape of thetransparent portion 810 is shown, however shapes such as an hourglass shape described above, or other shapes are within the scope of the invention. - A number of
teeth 814 or other frictional protrusions are shown on surface of thetransparent portion 810 that is to be adjacent to the eye. By usingteeth 814, a surgeon may grip the sclera of the eye with one hand to prevent rotation of the eye and aid in visualizing the wound simultaneously while the sutures are being placed with the other hand. The ability to grip the sclera is particularly useful in embodiments described above because of increased friction of the sutures in selected embodiments. -
FIG. 9 shows an example of an eye 10 days after a procedure as described above.Arrow 902 indicates the wound, whilearrows 904 indicate sutures placed as described above. - Using embodiments described above, a number of advantages are realized. One advantage of wound closure devices and methods described above includes a simple and inexpensive alternative to knot tying after suturing to prevent leakage. Another advantage includes a biocompatible material that degrades over time to allow healing of the incision. Although suture procedures involving the eye are disclosed, any other suture location would benefit from the devices and methods disclosed.
- Although selected advantages are detailed above, the list is not intended to be exhaustive. Although specific embodiments have been illustrated and described herein, it will be appreciated by those of ordinary skill in the art that any arrangement which is calculated to achieve the same purpose may be substituted for the specific embodiment shown. This application is intended to cover any adaptations or variations of the present invention. It is to be understood that the above description is intended to be illustrative, and not restrictive. Combinations of the above embodiments, and other embodiments will be apparent to those of skill in the art upon reviewing the above description. The scope of the invention includes any other applications in which the above structures and fabrication methods are used. The scope of the invention should be determined with reference to the appended claims, along with the full scope of equivalents to which such claims are entitled.
Claims (8)
1. A suture, comprising:
a number of unidirectional, pressed in, side features to increase a pullout resistance of the suture along a first direction; and
a distal end protrusion to resist suture pullout from a second direction opposite the first direction.
2. A suture, comprising:
a portion of a suture, having a flattened cross section; and
a number of textured side features to increase a pullout resistance of the suture.
3. The suture of claim 2 , wherein the number of textured side features includes a pressed in cross-hatch pattern.
4. The suture of claim 2 , wherein the number of textured side features includes a number of unidirectional features.
5. The suture of claim 2 , wherein the number of textured side features includes a number of spaced apart knots.
6. An ophthalmic wound visualization device, comprising:
a substantially transparent portion to place in contact with an eye near an ophthalmic wound;
a handle to apply pressure to the substantially transparent portion; and
a suture clearance cutaway to facilitate insertion of a suture while the substantially transparent portion is in contact with the eye.
7. The ophthalmic wound visualization device of claim 6 , further including one or more frictional protrusions on one side of the substantially transparent portion.
8. The ophthalmic wound visualization device of claim 7 , wherein the frictional protrusions include a number of teeth.
Priority Applications (4)
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US12/895,058 US20110213386A1 (en) | 2009-10-01 | 2010-09-30 | Ophthalmic wound closure devices and methods |
US14/095,468 US20140094827A1 (en) | 2009-10-01 | 2013-12-03 | Ophthalmic wound closure devices and methods |
US16/123,613 US10918377B2 (en) | 2009-10-01 | 2018-09-06 | Ophthalmic wound closure devices and methods |
US17/154,990 US20210137517A1 (en) | 2009-10-01 | 2021-01-21 | Ophthalmic wound closure devices and methods |
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US24781809P | 2009-10-01 | 2009-10-01 | |
US12/895,058 US20110213386A1 (en) | 2009-10-01 | 2010-09-30 | Ophthalmic wound closure devices and methods |
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US14/095,468 Division US20140094827A1 (en) | 2009-10-01 | 2013-12-03 | Ophthalmic wound closure devices and methods |
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US16/123,613 Active 2031-01-23 US10918377B2 (en) | 2009-10-01 | 2018-09-06 | Ophthalmic wound closure devices and methods |
US17/154,990 Pending US20210137517A1 (en) | 2009-10-01 | 2021-01-21 | Ophthalmic wound closure devices and methods |
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US17/154,990 Pending US20210137517A1 (en) | 2009-10-01 | 2021-01-21 | Ophthalmic wound closure devices and methods |
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Cited By (4)
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US20150257932A1 (en) * | 2013-11-25 | 2015-09-17 | Innfocus, Inc. | Methods, Systems and Devices for Treating Glaucoma |
WO2015102965A3 (en) * | 2013-12-30 | 2015-11-12 | Ryan Edwin | Cannula tool and method |
CN109069292A (en) * | 2016-04-25 | 2018-12-21 | 诺华股份有限公司 | Automatic intraocular pressure filling |
US10918377B2 (en) | 2009-10-01 | 2021-02-16 | Edwin Ryan | Ophthalmic wound closure devices and methods |
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US20030149447A1 (en) * | 2002-02-01 | 2003-08-07 | Morency Steven David | Barbed surgical suture |
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US20070038249A1 (en) * | 2004-06-30 | 2007-02-15 | Alwin Kolster | Suture for wound closure, tissue approximation, tissue support, suspension and/or fixation |
US20090105753A1 (en) * | 2004-08-26 | 2009-04-23 | Prodesco, Inc. | Sutures and methods of making the same |
US20070257395A1 (en) * | 2006-05-04 | 2007-11-08 | David Lindh | Tissue holding devices and methods for making the same |
US20080221618A1 (en) * | 2007-03-09 | 2008-09-11 | Gaoyuan Chen | Co-extruded tissue grasping monofilament |
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US10918377B2 (en) | 2009-10-01 | 2021-02-16 | Edwin Ryan | Ophthalmic wound closure devices and methods |
US20150257932A1 (en) * | 2013-11-25 | 2015-09-17 | Innfocus, Inc. | Methods, Systems and Devices for Treating Glaucoma |
US10010450B2 (en) * | 2013-11-25 | 2018-07-03 | Innfocus, Inc. | Methods, systems and devices for treating glaucoma |
WO2015102965A3 (en) * | 2013-12-30 | 2015-11-12 | Ryan Edwin | Cannula tool and method |
US20160317351A1 (en) * | 2013-12-30 | 2016-11-03 | Edwin Ryan | Cannula tool and method |
US10675179B2 (en) * | 2013-12-30 | 2020-06-09 | Edwin Ryan | Cannula tool and method |
US11602455B2 (en) | 2013-12-30 | 2023-03-14 | Edwin Ryan | Cannula tool and method |
CN109069292A (en) * | 2016-04-25 | 2018-12-21 | 诺华股份有限公司 | Automatic intraocular pressure filling |
Also Published As
Publication number | Publication date |
---|---|
US20210137517A1 (en) | 2021-05-13 |
US10918377B2 (en) | 2021-02-16 |
US20140094827A1 (en) | 2014-04-03 |
US20190000442A1 (en) | 2019-01-03 |
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