US20050165366A1 - Medical tubing having variable characteristics and method of making same - Google Patents

Medical tubing having variable characteristics and method of making same Download PDF

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Publication number
US20050165366A1
US20050165366A1 US10/766,138 US76613804A US2005165366A1 US 20050165366 A1 US20050165366 A1 US 20050165366A1 US 76613804 A US76613804 A US 76613804A US 2005165366 A1 US2005165366 A1 US 2005165366A1
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US
United States
Prior art keywords
ring
shaped elements
mandrel
tube
tubing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US10/766,138
Inventor
John Brustad
Said Hilal
Nabil Hilal
Charles Hart
Gary Johnson
Serene Hilal
Ghassan Sakakine
Donald Gadberry
Edward Pingleton
Matthew Petrime
Payam Adlparvar
Carl Hadley
Kenneth Vu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Applied Medical Resources Corp
Original Assignee
Applied Medical Resources Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US10/766,138 priority Critical patent/US20050165366A1/en
Application filed by Applied Medical Resources Corp filed Critical Applied Medical Resources Corp
Assigned to APPLIED MEDICAL RESOURCES CORPORATION reassignment APPLIED MEDICAL RESOURCES CORPORATION ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: HILAL, SAID S., ADLPARVAR, PAYAM, HILAL, NABIL, HILAL, SERENE, JOHNSON, GARY M., PETRIME, MATTHEW M., BRUSTAD, JOHN R., GADBERRY, DONALD L., HADLEY, CARL B., PINGLETON, EDWARD D., SAKAKINE, GHASSAN, VU, KENNETH K., HART, CHARLES C.
Priority to US10/832,867 priority patent/US20050004515A1/en
Priority to PCT/US2005/001129 priority patent/WO2005072806A2/en
Priority to EP05705664A priority patent/EP1708776A2/en
Priority to JP2006551162A priority patent/JP2007524480A/en
Priority to CA002552244A priority patent/CA2552244A1/en
Priority to AU2005209187A priority patent/AU2005209187B2/en
Priority to US11/152,945 priority patent/US20050256452A1/en
Publication of US20050165366A1 publication Critical patent/US20050165366A1/en
Priority to US11/263,876 priority patent/US20060064054A1/en
Priority to US11/695,449 priority patent/US7850811B2/en
Priority to US11/750,235 priority patent/US20070260225A1/en
Priority to US11/750,847 priority patent/US8529719B2/en
Priority to US12/877,245 priority patent/US8715441B2/en
Priority to US12/950,782 priority patent/US8721826B2/en
Priority to AU2011200989A priority patent/AU2011200989B8/en
Priority to US13/965,405 priority patent/US8691035B2/en
Priority to US14/164,954 priority patent/US9675378B2/en
Priority to US14/223,032 priority patent/US9987460B2/en
Priority to US15/949,443 priority patent/US10765832B2/en
Abandoned legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0009Making of catheters or other medical or surgical tubes
    • A61M25/0012Making of catheters or other medical or surgical tubes with embedded structures, e.g. coils, braids, meshes, strands or radiopaque coils
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00064Constructional details of the endoscope body
    • A61B1/0011Manufacturing of endoscope parts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/005Flexible endoscopes
    • A61B1/0051Flexible endoscopes with controlled bending of insertion part
    • A61B1/0055Constructional details of insertion parts, e.g. vertebral elements
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34Trocars; Puncturing needles
    • A61B17/3417Details of tips or shafts, e.g. grooves, expandable, bendable; Multiple coaxial sliding cannulas, e.g. for dilating
    • A61B17/3421Cannulas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0043Catheters; Hollow probes characterised by structural features
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00234Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
    • A61B2017/00292Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery mounted on or guided by flexible, e.g. catheter-like, means
    • A61B2017/003Steerable
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0021Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0023Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
    • A61M25/0026Multi-lumen catheters with stationary elements
    • A61M2025/0034Multi-lumen catheters with stationary elements characterized by elements which are assembled, connected or fused, e.g. splittable tubes, outer sheaths creating lumina or separate cores
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0021Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0023Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
    • A61M25/0026Multi-lumen catheters with stationary elements
    • A61M2025/0037Multi-lumen catheters with stationary elements characterized by lumina being arranged side-by-side
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/08Tubes; Storage means specially adapted therefor
    • A61M2039/082Multi-lumen tubes

Definitions

  • This invention generally relates to medical devices and, more specifically, to medical tubing adapted for insertion into a body tissue or cavity having variable characteristics and method of making same.
  • Medical tubing includes tubing used as catheters, drain tubes, access ports, endoscope bodies and the like. The requirements for each type of medical tubing will depend on its use. In particular, a specific length of medical tubing may vary depending on each application. For example, a specific length of medical tubing may need to be very flexible and yet pushable, or it may need to be thin-walled and yet kink-resistant. In addition, the tubing may need to exhibit these properties in only specific regions.
  • a medical tubing having a length with variable characteristics and a method of making the tubing such that variations can occur along the length of the manufactured tubing.
  • a length of the tubing may be rigid for a length, becomes flexible for a length and then becomes rigid again for another length. It is also desirable to have large variations in the diameter of the tubing.
  • a tube that is extremely kink-resistant in a specific region. Kink-resistance with very thin walls is not obtainable through the current extrusion processes.
  • the invention is primarily directed to a medical tubing adapted for insertion into a body tissue or cavity and method of manufacturing different variations of the tubing along a length of the tubing.
  • the medical tubing includes a length with variable characteristics, the tubing comprising a plurality of individual, discrete, generally ring-shaped elements arranged in series and fused or bonded together forming a continuous tubular structure.
  • the ring-shaped elements may be formed of a thermoplastic or a thermoset material.
  • the ring-shaped elements may include plastic rings, metallic rings, un-reinforced plastic rings and/or metal reinforced plastic rings assembled along the length of the tubular structure to provide variable flexibility and kink-resistance.
  • the tubular structure may be bent, twisted or curved without kinking.
  • the tubular structure may have a cross-section that is circular, oval, rectangular, triangular, hexagonal or any geometric shape.
  • the ring-shaped elements may have different flexural modulus.
  • the ring-shaped elements may include a combination of flexible and rigid ring-shaped elements assembled along different portions or sections of the tubular structure, wherein as the tubular structure is bent, twisted or curved, the rigid ring-shaped elements provide reinforcement to maintain the size and shape of the lumen and the flexible ring-shaped elements operate to stretch and compress to prevent kinking.
  • the ring-shaped elements may be metallic and may be bonded with a resilient, flexible elastomeric adhesive, wherein the ring-shaped elements may have different lengths and may be fused closer or further apart to one another depending on the characteristics of a portion or section of the tubing.
  • the medical tubing may further comprise a secondary lumen and a pull wire to control the tubular structure.
  • at least one of the ring-shaped elements may be truncated to provide a bending bias.
  • the truncated elements may comprise of alternating flexible ring-shaped elements and rigid ring-shaped elements.
  • the ring-shaped elements may vary in diameter and/or composition in different portions or sections of the tubular structure.
  • some of the ring-shaped elements may be radiopaque, or the ring-shaped elements may comprise of different colors to operate as indicators along the tubular structure.
  • AV introducers urological sheaths, ureteral access sheaths, urethral and bladder access sheaths, kidney access sheaths, ureteral stents, trocar cannulas, suction/irrigation tubing, insufflation tubing, vacuum tubing, split sheath introducers, tracheostomy tubes, intubation tubes, gastronomy tubes, jujenostomy tubes, extracorporeal retrograde cholangeopancreatography catheters, endoscope shafts, drainage tubes, guide catheters, hydrocephalic shunts, guidewires, angioplasty and dilation balloons, vascular grafts, cholangiography catheters, vascular embolectomy/thrombectomy catheters, and central venous catheters.
  • a method of manufacturing the medical tubing having a length with variable characteristics comprising the steps of placing a plurality of ring-shaped elements upon a support member or mandrel in a series arrangement, and heating the plurality of ring-shaped elements to fuse them together over the support member or mandrel.
  • the method of the invention may further comprise the step of placing the plurality of ring-shaped elements upon a second support member or mandrel before the heating step to subsequently form a second lumen or control tube to the tubular structure.
  • This method may further comprise the step of forming a control tube over the assembled ring-shaped elements prior to the heating step.
  • the control tube may comprise at least one of glass, silicone, heat shrinkable polyolefin, PTFE, FEP, metallic or other tubing that has a higher melting temperature than the assembled ring-shaped elements.
  • This method may further comprise the step of coating the tubular structure with an elastomeric adhesive or dispersion.
  • the mandrel may have a pre-formed curvature for accessing a specific region of a body cavity, the mandrel may include a collapsible, inflatable or dissolvable mandrel allowing the tubular structure to vary in diameter and lumen size, and the mandrel may be formed of an electrically dissolvable epoxy resin.
  • a method of manufacturing a medical tubing having a length with variable characteristics comprising the steps of placing a plurality of ring-shaped elements upon a support member or mandrel in a series arrangement, and fusing the plurality of ring-shaped elements together over the support member or mandrel with a solvent or other chemical compound.
  • the fusing step may further comprise the step of immersing the ring-shaped elements into the solvent to fuse the elements.
  • a method of manufacturing a medical tubing having a length with variable characteristics comprising the steps of placing a plurality of ring-shaped elements upon a support member or mandrel in a series arrangement, and bonding together the plurality of ring-shaped elements upon a support member or mandrel with an adhesive.
  • the adhesive may be photodynamic or heat-activated.
  • a method of manufacturing a thin-walled tube comprising the steps of coating a wire with a plastic material, wrapping the coated wire around a mandrel forming a plurality of windings, and heating the wound coated wire until the plastic material melts and bonds the windings forming a wire-reinforced tube.
  • the plastic material may comprise at least one of polyurethane, a thermoplastic material and a thermoset material.
  • the wire may comprise at least one of a metallic material and a second plastic material, or the wire may be coated with the plastic material in a coextrusion process. This method of the invention may further comprise the step of compressing the windings as the coated wire is being heated.
  • this method may further comprise the step of providing a mold to compress the windings.
  • This method may further comprise the step of removing the wire-reinforced tube from the mandrel after the tube is cooled.
  • the wound-coated tube may also be heated until the plastic material is formed above, below and between all the windings.
  • This method may further comprise the step of dipping the tube in a solvent-based solution forming an outer layer of the tube.
  • the mandrel may be tapered to provide the tube with varying diameter throughout the length of the tube
  • the coated wire may be alternatively wound with the filament around the mandrel
  • the mandrel may be any shape such that the resultant shape of the tube may be removed from the mandrel after the heating step
  • the mandrel may be a multiple-part mandrel.
  • a method of manufacturing a kink-resistant thin-walled tube having a length with different characteristics comprising the steps of coating a mandrel with a first layer of plastic material, placing a spring reinforcement over the first layer, and coating the spring reinforcement with a second layer of plastic material to form a spring-reinforced tube.
  • each of the first layer and the second layer may be formed in either an extrusion process or a molding process.
  • the spring reinforcement of the invention may be a pre-wound wire comprising at least one of a metallic material and a second plastic material.
  • the method of the invention may further comprise the step of dipping the tube in a solvent-based solution forming an outer layer of the tube.
  • another method of manufacturing a kink-resistant thin-walled tube having a length with different characteristics comprising the steps of coating a mandrel with a first layer of plastic material, placing a spring reinforcement over the first layer, and dipping the spring-reinforced first layer in a solvent based solution to form a second layer of the tube.
  • the second layer is impervious
  • the mandrel may be tapered to provide the tube with varying diameter throughout the length of the tube, and the mandrel may be any shape such that the resultant shape of the tube may be removed from the mandrel.
  • FIG. 1 illustrates a perspective view of a length of medical tubing according to a first embodiment of the invention
  • FIG. 2 illustrates a perspective view of a single plastic ring of the tubing of the invention to be arranged in a series;
  • FIG. 3 illustrates a perspective view of the medical tubing of the invention being formed according to a process of the invention
  • FIG. 4 is a side view of a composite tube of the invention in a straight condition
  • FIG. 5 is a side view of the composite tube of FIG. 4 in a bent condition
  • FIG. 6 is an end view of the composite tube of FIG. 4 ;
  • FIG. 7 is a side view of a tube having a bending bias in accordance with another embodiment of the invention.
  • FIG. 8 is an end view of the tube of FIG. 7 having a bending bias
  • FIG. 9 is a side view of a wire-ring reinforced tube in a straight condition in accordance with another embodiment of the invention.
  • FIG. 10 is a side view of the wire-ring reinforced tube of FIG. 9 in a bent or circular condition
  • FIG. 11 is an end view of the wire-ring reinforced tube of FIG. 9 ;
  • FIGS. 12 ( a ) and 12 ( b ) illustrate perspective views of tubes having varying diameters in accordance with additional embodiments of the invention.
  • FIG. 1 A medical tubing is illustrated in FIG. 1 and is designated by reference numeral 10 .
  • the medical tubing 10 is adapted for insertion into a body tissue or cavity.
  • the tubing 10 has a proximal end 12 , a distal end 14 , a length and at least one lumen 15 .
  • the tubing 10 is constructed of a plurality of individual, discrete, generally ring-shaped elements 16 arranged in series to form a continuous tubular structure 18 .
  • FIG. 2 illustrates a perspective view of a single generally ring-shaped plastic ring 16 of the tubing 10 of the invention to be arranged in a series.
  • the ring-shaped elements 16 are formed of a thermoplastic material.
  • the ring-shaped elements 16 are formed of a thermoset material.
  • the ring-shaped elements 16 may be arranged in series and subsequently fused or bonded by heat or chemical reaction to form a substantially continuous form.
  • tubing constructed from a series of individual, discreet elements may be bent, shaped or coiled without kinking.
  • the tubing 10 may have variable characteristics along the length. This may be achieved, for example, by the use of the ring-shaped elements 16 to provide different flexural modulus.
  • a length of tubing may be constructed wherein flexible ring-shaped elements are separated by rigid ring-shaped elements, i.e., a flexible portion of a tubular structure may be formed adjacent to a rigid or semi-rigid portion of the tubular structure to provide variable flexibility.
  • Such construction allows softer, more flexible material to be displaced and stretched along a curvature so that the rigid material is not deformed.
  • a preferred embodiment may comprise a thermoplastic of a very rigid nature spaced by a compatible thermoplastic of a very soft nature.
  • the ring-shaped elements 16 may be formed of two or more different materials having different chemical composition and hardness that are alternately fused or bonded together to form a continuous tube having circumferential portions that are alternately rigid and flexible.
  • the process of manufacturing the medical tubing 10 comprises the steps of placing the plurality of ring-shaped elements 16 upon the support member or mandrel 20 in a series arrangement; and heating the plurality of ring-shaped elements 16 to fuse them together over the support member or mandrel 20 . Additional lumens may be incorporated into the formed tubular structure 18 and supporting them with, e.g., an elongate wire. The arranged or assembled ring-shaped elements 16 are then heated so that the ring-shaped elements 16 are fused together over the mandrel(s) 20 .
  • a control tube is placed over the arranged or assembled ring-shaped elements 16 prior to the application of heat.
  • the control tube may comprise of glass, silicone, heat shrinkable polyolefin, PTFE, FEP, metallic or other tubing that has a higher melting temperature than the assembled ring-shaped elements 16 .
  • a silicone control tube may be placed over the assembled ring-shaped elements 16 as the control tube and the assembled ring-shaped elements 16 are placed in an oven until the plastic ring-shaped elements 16 have fused together.
  • the mandrel 20 may be heated until the thermoplastic ring-shaped elements 16 have fused together. The control tube and the mandrel(s) 20 are subsequently removed from the tubing 10 .
  • the ring-shaped elements 16 could have either an inner diameter or an outer diameter or a combination of both comprising of thermoplastic or applied thermoset material along with the mandrel 20 .
  • a compression sleeve of silicone tubing could be placed over the structure and either heated or allowed to cure. The resulting product once the compression sleeve is removed would be very flexible and malleable and yet would have tremendous column strength. This structure and variants thereof would be applicable, e.g., to the malleable shaft graspers.
  • the nested springs could be replaced with U-joints of various types.
  • thermoset material as follows.
  • the spring wire is wound on the mandrel with the desired pitch. It is then coated in the thermoset such as silicone.
  • the silicone compression tube is placed over the spring wire and the assembly is allowed to cure. The tube is then removed from the silicone tube and mandrel.
  • Springs can be pre-wound and can be made of materials other than steel that would otherwise not tolerate the heat required to flow a thermoplastic.
  • the entire process can be accomplished in the opposite manner to achieve the same results. This may be done by pre-winding a co-extruded wire into a spring and inserting it into a tube of desired diameter. A balloon or other such mechanism for pressurizing the spring coil may be inserted as the mandrel in the I.D. and the assembly are heated. As a result, the compression member is on the inside and the static member is on the outside.
  • coating the mandrels with various types of low friction surfaces assist in the removal of the finished tube.
  • Teflon coatings and various mold releases have been found to be effective.
  • Multiple lumens can also be easily included in the fusing or bonding process of the invention. This can be accomplished in numerous ways. The first is to provide a groove in the winding mandrel and place a stainless tube in the groove. The winding extrusion is placed on the mandrel as before. When the resulting assembly is removed, the stainless tube will be imbedded in the plastic of the wire extrusion. Another way to accomplish multiple lumens is to wind separate mandrels with the wire extrusion and then instead of placing the silicone compression sleeve around each mandrel individually the mandrel assemblies are placed next to each other and the compression sleeve is placed over both of them.
  • Mandrels can be of a variety of shapes to give the lumens of the resulting tube different internal and external shapes. Another version of this concept would be to assemble the mandrels with a strip or extrusion of plastic material (or non-plastic may work as well) in between the mandrels and then the assembled mandrels can have the extruded wire wound around them. The assembly would then be fused or bonded and the plastic in between the mandrels would form very thin walled lumens.
  • lumens can be placed external or internal to the main lumen of a catheter.
  • Tremendous advantages in overall size of the catheters can be achieved because unlike conventional extrusion techniques which require that wall thickness be maintained constant, the catheters of the invention can have wall thickness not only of localized thickness increases but also lengths or sections of different materials.
  • FIGS. 1-6 illustrate a relationship between a diameter of a tube and a wall thickness of that tube.
  • tubing having a large diameter (0.200′′ or larger) and a very thin wall (0.015′′ or less) is extremely subject to kinking when it is bent, coiled or twisted.
  • tubing constructed according to the present invention does not kink under the same circumstances since the softer materials allow bending without deformation of the primary, rigid material.
  • the rigid material acts as a reinforcement to maintain the size and shape of the lumen whereas the soft material stretches along the large arc and compresses along the short arc.
  • the stresses that normally accumulate along a thin walled tube and cause it to kink are absorbed and distributed in the composite construction of the present invention so that the tubing does not kink.
  • Kink-free tubing may be constructed having wall thickness to diameter ratios in excess of 20:1, which in a standard extrusion is not possible.
  • Wire coil reinforced tubing allows tubing to be made with a very thin wall. High diameter to wall ratios are possible when a wire coil is used to reinforce an extruded tube.
  • wire reinforcement creates hysterisis and makes the formation of additional lumens problematic.
  • a method of manufacturing the medical tubing 10 having variable characteristics comprising the steps of placing the plurality of ring-shaped elements 16 upon the support member or mandrel 20 in a series arrangement; and fusing the plurality of ring-shaped elements 16 together over the support member or mandrel 20 with a solvent or other chemical compound. That is, this embodiment contemplates the use of solvent materials to fuse the various ring-shaped elements 16 together to form the continuous tubular structure 18 .
  • the ring-shaped elements 16 may be arranged or assembled upon the support member or mandrel 20 in a desired sequence for specific applications. Then, a solvent may be applied to the assembled elements so that they are fused together to form a continuous length of tubing.
  • the assembled elements 16 may be immersed into a solvent to fuse the elements.
  • an adhesive may be used to adhere the various ring-shaped elements 16 together to form the continuous tubular structure 18 .
  • a heat-activated adhesive may be formed as a ring-shaped element and placed between each of the rigid and flexible ring-shaped elements 16 . When heat is applied, the adhesive is activated and the ring-shaped elements 16 are bonded.
  • a photodynamic adhesive may be used to bond the ring-shaped elements 16 .
  • adhesives include epoxies that are cured by application of UV light. Other adhesives, such as cyanoacrylates and various rubber cements may be used to achieve specific results.
  • Another aspect of the invention contemplates the use of a highly resilient, flexible rubber-like adhesive, such as silicone or other elastomeric adhesive, to bond the rigid ring-shaped elements 16 together.
  • a highly resilient, flexible rubber-like adhesive such as silicone or other elastomeric adhesive
  • Such a construction allows the bond to absorb and distribute the forces that would normally kink a large-diameter, thin-walled tube and maintain the shape of the lumen.
  • a series of rigid ring-shaped elements may be loosely assembled upon a mandrel or form and subsequently coated with an elastomeric adhesive or dispersion.
  • the elastomeric adhesive material that flows between the rigid ring-shaped elements forms a resilient, flexible region between the rigid elements.
  • An alternate embodiment contemplates the use of metallic rings assembled upon a mandrel and subsequently bonded together with a resilient, flexible elastomeric adhesive.
  • the bending characteristics of such a construction may be imparted by varying the length of the metallic ring-shaped elements.
  • a semi-rigid portion may be comprised of metallic ring-shaped elements that are long in comparison to the metallic ring-shaped elements of a flexible portion.
  • the metallic ring-shaped elements of the flexible portion are shorter allowing a tighter or smaller bending radius.
  • the tubing and process of manufacturing of the tubing of the invention provide a distinct advantage over extrusion in that a sensitive flexible portion may be reinforced while less sensitive regions may be left alone or un-reinforced. Additionally, there are many medical applications where only a portion of the tubing should be flexible while other portions should be rigid or semi-rigid. There are also applications where a portion must be very soft and flexible but must also be non-compressible and kink-free and yet have a portion rigid enough to allow navigation through tortuous lumens. An example of conflicting requirements include endoscope shafts, urinary, billiary and vascular catheters as further described below. Many of these devices could benefit from a thin-walled tube that has a large primary lumen, one or more secondary lumens and a very flexible portion that may be controlled by pull wire(s) or cable(s) within the secondary lumen(s).
  • a length of tubing 30 having alternating ring-shaped elements 32 that are shaped to provide a preferred bending bias 36 .
  • the more rigid ring-shaped elements 32 a are truncated or wedge-shaped, as are the less rigid elements 32 b .
  • a preferred arrangement of alternating truncated or wedge-shaped elements 32 a and 32 b provides the preferred bending bias 36 .
  • the larger flexible portion adjacent to the smaller rigid portion and is opposed to the smaller flexible portion adjacent to the larger rigid portion provides a bias toward the side having the larger flexible portion when a compression load is applied. The opposite is the case when a tension load is applied.
  • the biasing arrangement may be formed adjacent to a rigid or semi-rigid arrangement of discreet, individual ring-shaped elements.
  • FIG. 8 illustrates an end view of the tube having the bending bias of FIG. 7 .
  • FIGS. 9 and 10 are side views of a wire-ring reinforced tube in a straight and in a bent condition, respectively, in accordance with another embodiment of the invention, and
  • FIG. 11 is an end view of the wire-ring reinforced tube of FIG. 9 .
  • a length of tubing 40 is shown having a first diameter 42 and at least a second diameter 44 .
  • the differing diameters are a product of assembling various ring-shaped elements 46 upon a forming mandrel and fusing the elements 46 together to form a continuous tube. It can be seen that many different arrangements of smaller, larger, softer and harder materials may be assembled in any number of ways. In addition, various colored elements may be arranged as indicators or radiopaque elements may be assembled along the length of the assembled tube.
  • a rigid portion of tubing may be produced for a specific length at a specific diameter, followed by a semi-rigid portion at a second diameter (smaller or larger), followed by a very flexible portion at a third diameter (smaller or larger), followed by a rigid or semi-rigid portion at a fourth diameter (smaller or larger) and so on.
  • the present invention also contemplates the use of mandrels or forms that may have curves or other useful forms or shapes that fit various uses.
  • guiding catheters may be constructed that have pre-formed curvatures for accessing specific anatomical regions of a body.
  • Mandrels or forms may include collapsible, inflatable, dissolvable or the like that allow the tubular body to have variations in diameter and lumen size.
  • a mandrel or form may be constructed of an electrically dissolvable epoxy resin. The mandrel or form retains its shape until an electrical impulse is applied. The material separates upon application of electrical energy leaving a complex lumen shape within the tubular body.
  • This process results in a tube with walls of about 0.015′′ in thickness and a reinforced coil of stainless wire embedded in it.
  • the tube is virtually un-kinkable and has very smooth inner and outer diameter surfaces.
  • the mandrel can be tapered to provide a tube with variable diameters from one end to the other.
  • physical properties of the resulting tube can be adjusted by varying the diameter of the wire, the diameter of the co-extruded plastic, the type and properties of the wire and plastic such as chemical composition and hardness.
  • the tolerance that can be held on the I.D. of the tube is very high and on the order of 0.001′′ or less.
  • the tolerance on the O.D. is comparable.
  • the range of diameters for this process is quite large. Prototypes have been made from 0.026′′ I.D. to 0.75′′ I.D. and with wires from 0.004′′ diameter to 0.008′′ inch diameter.
  • wire/plastic extrusions can be wound together and the wire is not a requirement for this process to work. This process would be useful for molding thin wall tubes to dimensions that are not practical or obtainable by extrusion or traditional molding. Mandrels do not need to be round and could combine both round and non-round shapes on the same mandrel.
  • the main requirement is that the resultant shape be capable of being removed from the mandrel once the heat cycle is finished. With unusual shapes this could be accomplished with split mandrels and sacrificial mandrels that could be removed by dissolving in acid by way of example.
  • the method of the invention may be applied in the construction of the following products, at least in part if not in whole:
  • the sheath of the invention would be capable of being coated internally as well as externally with friction reducing coatings such as hydrophilic coatings as well as heperanized coatings or other medically beneficial surface treatment.

Abstract

The invention primarily is directed to a medical tubing adapted for insertion into a body tissue or cavity and method of manufacturing different variations of the tubing along a length of the tubing. The tubing comprises a plurality of individual, discrete, generally ring-shaped elements arranged in series and fused or bonded together forming a continuous tubular structure. The ring-shaped elements may be formed of a thermoplastic or a thermoset material. The ring-shaped elements may include plastic rings, metallic rings, un-reinforced plastic rings and/or metal reinforced plastic rings assembled along the length of the tubular structure to provide variable flexibility and kink-resistance. The tubular structure may have a cross-section of any geometric shape and it may be bent, twisted or curved without kinking. The ring-shaped elements may have different flexural modulus. The ring-shaped elements may include a combination of flexible and rigid ring-shaped elements assembled along different portions or sections of the tubular structure. The ring-shaped elements may be metallic and may be bonded with a resilient, flexible elastomeric adhesive, wherein the ring-shaped elements may have different lengths and may be fused closer or further apart to one another depending on the characteristics of a portion or section of the tubing. In another aspect of the invention, the medical tubing may further comprise a secondary lumen and a pull wire to control the tubular structure. The ring-shaped elements may be truncated to provide a bending bias. In another aspect of the invention, the ring-shaped elements may vary in diameter and/or composition in different portions or sections of the tubular structure. In yet another aspect of the invention, some of the ring-shaped elements may be radiopaque, or the ring-shaped elements may comprise of different colors to operate as indicators along the tubular structure.

Description

    BACKGROUND OF THE INVENTION
  • 1. Field of the Invention
  • This invention generally relates to medical devices and, more specifically, to medical tubing adapted for insertion into a body tissue or cavity having variable characteristics and method of making same.
  • 2. Discussion of Related Art
  • Medical tubing includes tubing used as catheters, drain tubes, access ports, endoscope bodies and the like. The requirements for each type of medical tubing will depend on its use. In particular, a specific length of medical tubing may vary depending on each application. For example, a specific length of medical tubing may need to be very flexible and yet pushable, or it may need to be thin-walled and yet kink-resistant. In addition, the tubing may need to exhibit these properties in only specific regions.
  • Most medical tubing is extruded from a single plastic material in a continuous forming process. Certain characteristics or variations may be imparted to the extruded tubing by altering the speed or the tension of the extruded material as it exits and cools from the extrusion machine. However, the variations are limited by the fact that a single material is extruded. Recent advances in extrusion technology have allowed the co-extrusion of multiple materials. This provides some usable variations in extruded tubing. Nevertheless, this is still a linear process and is still limited by the continuous flow of the extruded materials.
  • Accordingly, there is a need for a medical tubing having a length with variable characteristics and a method of making the tubing such that variations can occur along the length of the manufactured tubing. For instance, a length of the tubing may be rigid for a length, becomes flexible for a length and then becomes rigid again for another length. It is also desirable to have large variations in the diameter of the tubing. In another application, there may be a need for a tube that is extremely kink-resistant in a specific region. Kink-resistance with very thin walls is not obtainable through the current extrusion processes.
  • SUMMARY OF THE INVENTION
  • The invention is primarily directed to a medical tubing adapted for insertion into a body tissue or cavity and method of manufacturing different variations of the tubing along a length of the tubing. In one aspect of the invention, the medical tubing includes a length with variable characteristics, the tubing comprising a plurality of individual, discrete, generally ring-shaped elements arranged in series and fused or bonded together forming a continuous tubular structure. The ring-shaped elements may be formed of a thermoplastic or a thermoset material. The ring-shaped elements may include plastic rings, metallic rings, un-reinforced plastic rings and/or metal reinforced plastic rings assembled along the length of the tubular structure to provide variable flexibility and kink-resistance. The tubular structure may be bent, twisted or curved without kinking. The tubular structure may have a cross-section that is circular, oval, rectangular, triangular, hexagonal or any geometric shape. The ring-shaped elements may have different flexural modulus. The ring-shaped elements may include a combination of flexible and rigid ring-shaped elements assembled along different portions or sections of the tubular structure, wherein as the tubular structure is bent, twisted or curved, the rigid ring-shaped elements provide reinforcement to maintain the size and shape of the lumen and the flexible ring-shaped elements operate to stretch and compress to prevent kinking. The ring-shaped elements may be metallic and may be bonded with a resilient, flexible elastomeric adhesive, wherein the ring-shaped elements may have different lengths and may be fused closer or further apart to one another depending on the characteristics of a portion or section of the tubing.
  • In another aspect of the invention, the medical tubing may further comprise a secondary lumen and a pull wire to control the tubular structure. It is appreciated that at least one of the ring-shaped elements may be truncated to provide a bending bias. The truncated elements may comprise of alternating flexible ring-shaped elements and rigid ring-shaped elements. In yet another aspect of the invention, the ring-shaped elements may vary in diameter and/or composition in different portions or sections of the tubular structure. In another aspect of the invention, some of the ring-shaped elements may be radiopaque, or the ring-shaped elements may comprise of different colors to operate as indicators along the tubular structure. Applications of the medical tubing of the invention include AV introducers, urological sheaths, ureteral access sheaths, urethral and bladder access sheaths, kidney access sheaths, ureteral stents, trocar cannulas, suction/irrigation tubing, insufflation tubing, vacuum tubing, split sheath introducers, tracheostomy tubes, intubation tubes, gastronomy tubes, jujenostomy tubes, extracorporeal retrograde cholangeopancreatography catheters, endoscope shafts, drainage tubes, guide catheters, hydrocephalic shunts, guidewires, angioplasty and dilation balloons, vascular grafts, cholangiography catheters, vascular embolectomy/thrombectomy catheters, and central venous catheters.
  • In another aspect of the invention, a method of manufacturing the medical tubing having a length with variable characteristics is disclosed, the method comprising the steps of placing a plurality of ring-shaped elements upon a support member or mandrel in a series arrangement, and heating the plurality of ring-shaped elements to fuse them together over the support member or mandrel. The method of the invention may further comprise the step of placing the plurality of ring-shaped elements upon a second support member or mandrel before the heating step to subsequently form a second lumen or control tube to the tubular structure. This method may further comprise the step of forming a control tube over the assembled ring-shaped elements prior to the heating step. The control tube may comprise at least one of glass, silicone, heat shrinkable polyolefin, PTFE, FEP, metallic or other tubing that has a higher melting temperature than the assembled ring-shaped elements. This method may further comprise the step of coating the tubular structure with an elastomeric adhesive or dispersion. In another aspect of the invention, the mandrel may have a pre-formed curvature for accessing a specific region of a body cavity, the mandrel may include a collapsible, inflatable or dissolvable mandrel allowing the tubular structure to vary in diameter and lumen size, and the mandrel may be formed of an electrically dissolvable epoxy resin.
  • In another aspect of the invention, a method of manufacturing a medical tubing having a length with variable characteristics is disclosed, the method comprising the steps of placing a plurality of ring-shaped elements upon a support member or mandrel in a series arrangement, and fusing the plurality of ring-shaped elements together over the support member or mandrel with a solvent or other chemical compound. In this method of the invention, the fusing step may further comprise the step of immersing the ring-shaped elements into the solvent to fuse the elements.
  • In another aspect of the invention, a method of manufacturing a medical tubing having a length with variable characteristics is disclosed, the method comprising the steps of placing a plurality of ring-shaped elements upon a support member or mandrel in a series arrangement, and bonding together the plurality of ring-shaped elements upon a support member or mandrel with an adhesive. The adhesive may be photodynamic or heat-activated.
  • In another aspect of the invention, a method of manufacturing a thin-walled tube is disclosed comprising the steps of coating a wire with a plastic material, wrapping the coated wire around a mandrel forming a plurality of windings, and heating the wound coated wire until the plastic material melts and bonds the windings forming a wire-reinforced tube. In this method of the invention, the plastic material may comprise at least one of polyurethane, a thermoplastic material and a thermoset material. In another aspect of the invention, the wire may comprise at least one of a metallic material and a second plastic material, or the wire may be coated with the plastic material in a coextrusion process. This method of the invention may further comprise the step of compressing the windings as the coated wire is being heated.
  • In another aspect of the invention, this method may further comprise the step of providing a mold to compress the windings. This method may further comprise the step of removing the wire-reinforced tube from the mandrel after the tube is cooled. The wound-coated tube may also be heated until the plastic material is formed above, below and between all the windings. This method may further comprise the step of dipping the tube in a solvent-based solution forming an outer layer of the tube. In other aspects of the invention, the mandrel may be tapered to provide the tube with varying diameter throughout the length of the tube, the coated wire may be alternatively wound with the filament around the mandrel, the mandrel may be any shape such that the resultant shape of the tube may be removed from the mandrel after the heating step, and the mandrel may be a multiple-part mandrel.
  • In another aspect of the invention, a method of manufacturing a kink-resistant thin-walled tube having a length with different characteristics is disclosed, the method comprising the steps of coating a mandrel with a first layer of plastic material, placing a spring reinforcement over the first layer, and coating the spring reinforcement with a second layer of plastic material to form a spring-reinforced tube. In this method of the invention, each of the first layer and the second layer may be formed in either an extrusion process or a molding process. The spring reinforcement of the invention may be a pre-wound wire comprising at least one of a metallic material and a second plastic material. The method of the invention may further comprise the step of dipping the tube in a solvent-based solution forming an outer layer of the tube.
  • In another aspect of the invention, another method of manufacturing a kink-resistant thin-walled tube having a length with different characteristics is disclosed, the method comprising the steps of coating a mandrel with a first layer of plastic material, placing a spring reinforcement over the first layer, and dipping the spring-reinforced first layer in a solvent based solution to form a second layer of the tube. In this method of the invention, the second layer is impervious, the mandrel may be tapered to provide the tube with varying diameter throughout the length of the tube, and the mandrel may be any shape such that the resultant shape of the tube may be removed from the mandrel.
  • DESCRIPTION OF THE DRAWINGS
  • FIG. 1 illustrates a perspective view of a length of medical tubing according to a first embodiment of the invention;
  • FIG. 2 illustrates a perspective view of a single plastic ring of the tubing of the invention to be arranged in a series;
  • FIG. 3 illustrates a perspective view of the medical tubing of the invention being formed according to a process of the invention;
  • FIG. 4 is a side view of a composite tube of the invention in a straight condition;
  • FIG. 5 is a side view of the composite tube of FIG. 4 in a bent condition;
  • FIG. 6 is an end view of the composite tube of FIG. 4;
  • FIG. 7 is a side view of a tube having a bending bias in accordance with another embodiment of the invention;
  • FIG. 8 is an end view of the tube of FIG. 7 having a bending bias;
  • FIG. 9 is a side view of a wire-ring reinforced tube in a straight condition in accordance with another embodiment of the invention;
  • FIG. 10 is a side view of the wire-ring reinforced tube of FIG. 9 in a bent or circular condition;
  • FIG. 11 is an end view of the wire-ring reinforced tube of FIG. 9; and
  • FIGS. 12(a) and 12(b) illustrate perspective views of tubes having varying diameters in accordance with additional embodiments of the invention.
  • DESCRIPTION OF PREFERRED EMBODIMENTS AND BEST MODE OF THE INVENTION
  • A medical tubing is illustrated in FIG. 1 and is designated by reference numeral 10. The medical tubing 10 is adapted for insertion into a body tissue or cavity. The tubing 10 has a proximal end 12, a distal end 14, a length and at least one lumen 15. The tubing 10 is constructed of a plurality of individual, discrete, generally ring-shaped elements 16 arranged in series to form a continuous tubular structure 18. FIG. 2 illustrates a perspective view of a single generally ring-shaped plastic ring 16 of the tubing 10 of the invention to be arranged in a series. In one aspect of the invention, the ring-shaped elements 16 are formed of a thermoplastic material. In another aspect of the invention, the ring-shaped elements 16 are formed of a thermoset material. The ring-shaped elements 16 may be arranged in series and subsequently fused or bonded by heat or chemical reaction to form a substantially continuous form.
  • Referring to FIG. 5, it can be seen that tubing constructed from a series of individual, discreet elements may be bent, shaped or coiled without kinking. In particular, the tubing 10 may have variable characteristics along the length. This may be achieved, for example, by the use of the ring-shaped elements 16 to provide different flexural modulus. For instance, a length of tubing may be constructed wherein flexible ring-shaped elements are separated by rigid ring-shaped elements, i.e., a flexible portion of a tubular structure may be formed adjacent to a rigid or semi-rigid portion of the tubular structure to provide variable flexibility. Such construction allows softer, more flexible material to be displaced and stretched along a curvature so that the rigid material is not deformed. A preferred embodiment may comprise a thermoplastic of a very rigid nature spaced by a compatible thermoplastic of a very soft nature. In other words, the ring-shaped elements 16 may be formed of two or more different materials having different chemical composition and hardness that are alternately fused or bonded together to form a continuous tube having circumferential portions that are alternately rigid and flexible.
  • Referring back to FIG. 3, there is shown a process of manufacturing the medical tubing 10 having variable characteristics of the invention where a support member or mandrel 20 is used to hold an assembly of ring-shaped elements 16 in an elongate, series arrangement. In particular, the process of manufacturing the medical tubing 10 comprises the steps of placing the plurality of ring-shaped elements 16 upon the support member or mandrel 20 in a series arrangement; and heating the plurality of ring-shaped elements 16 to fuse them together over the support member or mandrel 20. Additional lumens may be incorporated into the formed tubular structure 18 and supporting them with, e.g., an elongate wire. The arranged or assembled ring-shaped elements 16 are then heated so that the ring-shaped elements 16 are fused together over the mandrel(s) 20.
  • In another aspect of the invention, it is contemplated that a control tube is placed over the arranged or assembled ring-shaped elements 16 prior to the application of heat. The control tube may comprise of glass, silicone, heat shrinkable polyolefin, PTFE, FEP, metallic or other tubing that has a higher melting temperature than the assembled ring-shaped elements 16. A silicone control tube may be placed over the assembled ring-shaped elements 16 as the control tube and the assembled ring-shaped elements 16 are placed in an oven until the plastic ring-shaped elements 16 have fused together. Alternatively, the mandrel 20 may be heated until the thermoplastic ring-shaped elements 16 have fused together. The control tube and the mandrel(s) 20 are subsequently removed from the tubing 10.
  • In another aspect of the invention, the ring-shaped elements 16 could have either an inner diameter or an outer diameter or a combination of both comprising of thermoplastic or applied thermoset material along with the mandrel 20. A compression sleeve of silicone tubing could be placed over the structure and either heated or allowed to cure. The resulting product once the compression sleeve is removed would be very flexible and malleable and yet would have tremendous column strength. This structure and variants thereof would be applicable, e.g., to the malleable shaft graspers. In another aspect, the nested springs could be replaced with U-joints of various types.
  • Alternatively, the process of the invention could be accomplished with a thermoset material as follows. The spring wire is wound on the mandrel with the desired pitch. It is then coated in the thermoset such as silicone. Next, the silicone compression tube is placed over the spring wire and the assembly is allowed to cure. The tube is then removed from the silicone tube and mandrel. Springs can be pre-wound and can be made of materials other than steel that would otherwise not tolerate the heat required to flow a thermoplastic.
  • In another aspect of the invention, the entire process can be accomplished in the opposite manner to achieve the same results. This may be done by pre-winding a co-extruded wire into a spring and inserting it into a tube of desired diameter. A balloon or other such mechanism for pressurizing the spring coil may be inserted as the mandrel in the I.D. and the assembly are heated. As a result, the compression member is on the inside and the static member is on the outside.
  • It is appreciated that coating the mandrels with various types of low friction surfaces assist in the removal of the finished tube. For example, Teflon coatings and various mold releases have been found to be effective.
  • Multiple lumens can also be easily included in the fusing or bonding process of the invention. This can be accomplished in numerous ways. The first is to provide a groove in the winding mandrel and place a stainless tube in the groove. The winding extrusion is placed on the mandrel as before. When the resulting assembly is removed, the stainless tube will be imbedded in the plastic of the wire extrusion. Another way to accomplish multiple lumens is to wind separate mandrels with the wire extrusion and then instead of placing the silicone compression sleeve around each mandrel individually the mandrel assemblies are placed next to each other and the compression sleeve is placed over both of them. Mandrels can be of a variety of shapes to give the lumens of the resulting tube different internal and external shapes. Another version of this concept would be to assemble the mandrels with a strip or extrusion of plastic material (or non-plastic may work as well) in between the mandrels and then the assembled mandrels can have the extruded wire wound around them. The assembly would then be fused or bonded and the plastic in between the mandrels would form very thin walled lumens.
  • As such, it is appreciated that lumens can be placed external or internal to the main lumen of a catheter. Tremendous advantages in overall size of the catheters can be achieved because unlike conventional extrusion techniques which require that wall thickness be maintained constant, the catheters of the invention can have wall thickness not only of localized thickness increases but also lengths or sections of different materials.
  • The tubing constructed according to the present invention is especially unique in that it may be constructed having an extremely thin wall section. FIGS. 1-6 illustrate a relationship between a diameter of a tube and a wall thickness of that tube. Normally, tubing having a large diameter (0.200″ or larger) and a very thin wall (0.015″ or less) is extremely subject to kinking when it is bent, coiled or twisted. However, tubing constructed according to the present invention does not kink under the same circumstances since the softer materials allow bending without deformation of the primary, rigid material. It can be seen that as the tubing is bent, shaped or curved, the rigid material acts as a reinforcement to maintain the size and shape of the lumen whereas the soft material stretches along the large arc and compresses along the short arc. The stresses that normally accumulate along a thin walled tube and cause it to kink are absorbed and distributed in the composite construction of the present invention so that the tubing does not kink. Kink-free tubing may be constructed having wall thickness to diameter ratios in excess of 20:1, which in a standard extrusion is not possible. Wire coil reinforced tubing allows tubing to be made with a very thin wall. High diameter to wall ratios are possible when a wire coil is used to reinforce an extruded tube. However, wire reinforcement creates hysterisis and makes the formation of additional lumens problematic. In addition, it requires that formation of the tubing be done in a continuous form, not allowing for variations at specific regions along the length of the tubing.
  • In another embodiment of the invention, a method of manufacturing the medical tubing 10 having variable characteristics is disclosed, the method comprising the steps of placing the plurality of ring-shaped elements 16 upon the support member or mandrel 20 in a series arrangement; and fusing the plurality of ring-shaped elements 16 together over the support member or mandrel 20 with a solvent or other chemical compound. That is, this embodiment contemplates the use of solvent materials to fuse the various ring-shaped elements 16 together to form the continuous tubular structure 18. The ring-shaped elements 16 may be arranged or assembled upon the support member or mandrel 20 in a desired sequence for specific applications. Then, a solvent may be applied to the assembled elements so that they are fused together to form a continuous length of tubing. In another aspect of the invention, the assembled elements 16 may be immersed into a solvent to fuse the elements.
  • In yet another embodiment of the invention, an adhesive may be used to adhere the various ring-shaped elements 16 together to form the continuous tubular structure 18. For instance, a heat-activated adhesive may be formed as a ring-shaped element and placed between each of the rigid and flexible ring-shaped elements 16. When heat is applied, the adhesive is activated and the ring-shaped elements 16 are bonded. In another aspect, a photodynamic adhesive may be used to bond the ring-shaped elements 16. Such adhesives include epoxies that are cured by application of UV light. Other adhesives, such as cyanoacrylates and various rubber cements may be used to achieve specific results. Another aspect of the invention contemplates the use of a highly resilient, flexible rubber-like adhesive, such as silicone or other elastomeric adhesive, to bond the rigid ring-shaped elements 16 together. Such a construction allows the bond to absorb and distribute the forces that would normally kink a large-diameter, thin-walled tube and maintain the shape of the lumen. For instance, a series of rigid ring-shaped elements may be loosely assembled upon a mandrel or form and subsequently coated with an elastomeric adhesive or dispersion. The elastomeric adhesive material that flows between the rigid ring-shaped elements forms a resilient, flexible region between the rigid elements. An alternate embodiment contemplates the use of metallic rings assembled upon a mandrel and subsequently bonded together with a resilient, flexible elastomeric adhesive. The bending characteristics of such a construction may be imparted by varying the length of the metallic ring-shaped elements. For instance, a semi-rigid portion may be comprised of metallic ring-shaped elements that are long in comparison to the metallic ring-shaped elements of a flexible portion. The metallic ring-shaped elements of the flexible portion are shorter allowing a tighter or smaller bending radius.
  • The tubing and process of manufacturing of the tubing of the invention provide a distinct advantage over extrusion in that a sensitive flexible portion may be reinforced while less sensitive regions may be left alone or un-reinforced. Additionally, there are many medical applications where only a portion of the tubing should be flexible while other portions should be rigid or semi-rigid. There are also applications where a portion must be very soft and flexible but must also be non-compressible and kink-free and yet have a portion rigid enough to allow navigation through tortuous lumens. An example of conflicting requirements include endoscope shafts, urinary, billiary and vascular catheters as further described below. Many of these devices could benefit from a thin-walled tube that has a large primary lumen, one or more secondary lumens and a very flexible portion that may be controlled by pull wire(s) or cable(s) within the secondary lumen(s).
  • Referring to FIG. 7, there is shown a length of tubing 30 according to another embodiment of the invention having alternating ring-shaped elements 32 that are shaped to provide a preferred bending bias 36. In this embodiment, the more rigid ring-shaped elements 32 a are truncated or wedge-shaped, as are the less rigid elements 32 b. A preferred arrangement of alternating truncated or wedge-shaped elements 32 a and 32 b provides the preferred bending bias 36. Stated another way, the larger flexible portion adjacent to the smaller rigid portion and is opposed to the smaller flexible portion adjacent to the larger rigid portion provides a bias toward the side having the larger flexible portion when a compression load is applied. The opposite is the case when a tension load is applied. As can be seen from the figures, the biasing arrangement may be formed adjacent to a rigid or semi-rigid arrangement of discreet, individual ring-shaped elements. FIG. 8 illustrates an end view of the tube having the bending bias of FIG. 7. FIGS. 9 and 10 are side views of a wire-ring reinforced tube in a straight and in a bent condition, respectively, in accordance with another embodiment of the invention, and FIG. 11 is an end view of the wire-ring reinforced tube of FIG. 9.
  • Referring to FIG. 12, a length of tubing 40 is shown having a first diameter 42 and at least a second diameter 44. The differing diameters are a product of assembling various ring-shaped elements 46 upon a forming mandrel and fusing the elements 46 together to form a continuous tube. It can be seen that many different arrangements of smaller, larger, softer and harder materials may be assembled in any number of ways. In addition, various colored elements may be arranged as indicators or radiopaque elements may be assembled along the length of the assembled tube. For example, a rigid portion of tubing may be produced for a specific length at a specific diameter, followed by a semi-rigid portion at a second diameter (smaller or larger), followed by a very flexible portion at a third diameter (smaller or larger), followed by a rigid or semi-rigid portion at a fourth diameter (smaller or larger) and so on.
  • The present invention also contemplates the use of mandrels or forms that may have curves or other useful forms or shapes that fit various uses. For instance, guiding catheters may be constructed that have pre-formed curvatures for accessing specific anatomical regions of a body. Mandrels or forms may include collapsible, inflatable, dissolvable or the like that allow the tubular body to have variations in diameter and lumen size. As an example, a mandrel or form may be constructed of an electrically dissolvable epoxy resin. The mandrel or form retains its shape until an electrical impulse is applied. The material separates upon application of electrical energy leaving a complex lumen shape within the tubular body.
  • The following is yet another example of a process for making thin-walled tubes of the invention:
      • (1) First, a mandrel of steel is machined to match the internal diameter or shape of the intended tube;
      • (2) Second, a stainless steel wire, e.g., of about 0.006″ in diameter has a layer of polyurethane co-extruded onto it with a resulting diameter of about 0.020″;
      • (3) The co-extruded wire is close wound around the length of the mandrel and the ends are secured such that the resultant coil will not unwind;
      • (4) Fourth, a silicone tube with an inner diameter (I.D.) less than that of the wound coil outer diameter (O.D.) is placed over the entire assembly such that it completely covers the wound coil;
      • (5) Fifth, the assembly is placed in an oven at approximately 180° C. for 15 to 30 minutes (this is for Pellethane; other plastics require different parameters.);
      • (6) Sixth, the assembly is removed from the oven and cooled. The silicone sheath is removed once the assembly has cooled; and
      • (7) Seventh, the wound coil is removed from the mandrel.
  • This process results in a tube with walls of about 0.015″ in thickness and a reinforced coil of stainless wire embedded in it. The tube is virtually un-kinkable and has very smooth inner and outer diameter surfaces. In addition, the mandrel can be tapered to provide a tube with variable diameters from one end to the other. In other examples, physical properties of the resulting tube can be adjusted by varying the diameter of the wire, the diameter of the co-extruded plastic, the type and properties of the wire and plastic such as chemical composition and hardness. The tolerance that can be held on the I.D. of the tube is very high and on the order of 0.001″ or less. The tolerance on the O.D. is comparable. The range of diameters for this process is quite large. Prototypes have been made from 0.026″ I.D. to 0.75″ I.D. and with wires from 0.004″ diameter to 0.008″ inch diameter.
  • It should be noted that two or more different types of wire/plastic extrusions can be wound together and the wire is not a requirement for this process to work. This process would be useful for molding thin wall tubes to dimensions that are not practical or obtainable by extrusion or traditional molding. Mandrels do not need to be round and could combine both round and non-round shapes on the same mandrel.
  • The main requirement is that the resultant shape be capable of being removed from the mandrel once the heat cycle is finished. With unusual shapes this could be accomplished with split mandrels and sacrificial mandrels that could be removed by dissolving in acid by way of example.
  • The method of the invention may be applied in the construction of the following products, at least in part if not in whole:
      • 1. AV introducers: These devices are used to gain access to blood vessels. The AV introducers of the prior art are typically fairly thick walled flouropolymer about 2-3 inches long. The AV introducers of the invention decrease wall thickness and at the same time increase kink resistance. Vascular surgeons also use longer versions of these to access various parts of the vascular system and then use these sheaths to inject various medicants or use them as a highway for the introduction and removal of instruments. These longer versions can be 70 centimeters in length or more and would benefit tremendously by the increased kink resistance and flexibility that the AV introducers of the invention would offer.
  • More specifically, the sheath of the invention would be capable of being coated internally as well as externally with friction reducing coatings such as hydrophilic coatings as well as heperanized coatings or other medically beneficial surface treatment.
      • 2. Urological sheaths: Different urological sheaths can be produced by the methods of the present invention, e.g., ureteral access sheaths, urethral and bladder access sheaths, and kidney access sheaths modified to direct a scope for various procedures.
      • 3. Ureteral stents: These can be made with the process of the invention and would have the benefits of thin walls, high column strength and tremendous flexibility. The common wisdom in urology is that thin flexible stents are more comfortable for the patient but more difficult for the physician to place. Larger more rigid stents are easier to place but uncomfortable for the patient. The stent of the invention would be both small and flexible and yet easy to place due to its inherent column strength.
      • 4. Trocar cannula: These can be made to be very thin walled and yet flexible (or inflexible), and can be very resistant to kinking or compressing. This may be achieved by the bonding or fusing process of the invention with a braided structure instead of a coil. In another aspect, a folded structure could be made that would allow the cannula sheath to be inserted first followed by the cannula itself.
      • 5. Suction/Irrigation (S/I) tubing: Prior art S/I tubing is currently made from PVC and is very thick walled to prevent the tube from kinking or collapsing under vacuum. With the process of the invention, the following benefits can be achieved—the tubing would be kink resistant yet have thin walls and therefore be lightweight, cost would be comparable to PVC without the environmental concern, thus, it would reduce the overall amount of plastic used. Currently, S/I tubes have 1 to 2 lbs of PVC tubing in them. The S/I tubing of the invention would reduce the overall weight of plastic to approximately {fraction (1/10)} of a pound and would be easier for the surgeon to use. In addition, the wire in the irrigation tube could be electrically heated to allow the fluid to be at or near body temperature when introduced to the patient.
      • 6. Insufflation tubing: This tubing is used to deliver carbon dioxide gas for laparoscopic surgery and has some of the same problems as S/I tubing. Lighter weight and less plastic wasteful tubing could be made, and the heating element in the wall would be of benefit to the patient by allowing body temperature gas to be introduced instead of colder gas.
      • 7. Vacuum tube: The process of the invention would be beneficial to any situation, either medical or non-medical, where the need exists for a vacuum tube to be thin walled and preferably kink resistant. This process could also be used to produce thin walled pressure tubes.
      • 8. Split sheath introducers: The process of the invention can be modified to make a split sheath introducer. The wire extrusion can be wound on a special mandrel to make a semicircular tube on each side of the mandrel and then fusing or bonding the split sheath together.
      • 9. Tracheostomy tubes: Thin walled kink-free tracheostomy tubes would benefit from the process of the invention. The balloon-filled lumen could be easily fused or bonded together along with the breathing tube. The same advantages would apply to crycothyrodectomy tubes used in emergency situations.
      • 10. Intubation tubes: The intubation tubes have very thin walls and are very kink resistant which would help enormously with these devices especially in pediatrics or cases where the trachea has become constricted. The flexibility would make them ideal for nasal tubes as well.
      • 11. G-tubes/J-tubes: Gastronomy and jujenostomy tubes are used for enteral feeding and would likewise benefit from reduced diameters, enhanced column strength for insertion, and kink resistance for safety.
      • 12. ERCP catheters: Extracoporeal retrograde cholangeopancreatography catheters are very long catheters typically used to treat gallstones in the cystic duct. These would benefit from the increased column strength and reduced wall thickness as well as high kink resistance.
      • 13. Endoscope shafts: Flexible and steerable endoscopes require shafts that can give good protection to the internal components as well as provide regions of variable flexibility and good column stiffness throughout. The shafts must also accommodate multiple lumens.
      • 14. Drainage tubes: Drainage and suction tubes would also benefit from thin walls, lightweight and kink resistance.
      • 15. Guide catheters: Guide catheters commonly used in cardiology to gain access to the coronary arteries are carefully designed to meet various design criteria such as shape, stiffness, steerability, torque strength and kink resistance. They have to be smooth and non-thrombogenic. The bonding and fusing process of the invention can serve as a good basis of construction for these devices. Torque strength or torqability can be improved in devices of the invention by putting relatively stiff elements along the length of the shaft or by altering the plastic used to extrude over the wire.
      • 16. Hydrocephalic shunts: A common problem with these shunts, which are used to drain excess hydrocephalic fluid from the ventricles of the brain, is that they can kink and prevent adequate drainage. This in turn can require a revision to be performed or merely patient discomfort and possibly increase the chances of an infection. By producing portions of them with the process of the invention, it is possible to create very crush as well as kink resistant shunts.
      • 17. Guidewires: Guidewires are used in a number of applications including urology and radiology. They are commonly constructed with close wound stainless steel springs and then coated with Teflon or a plastic for lubricity. They are typically 2 to 6 feet long and are around 1 mm in diameter or less. These structures can be fabricated with the process of the invention.
      • 18. Angioplasty and dilation balloons: The catheters that these balloons are placed on require the ability to transmit as much as 15 atmospheres or more over a 3-foot or longer length. Here again the advantages of reinforced thin walls with excellent column strength would be very helpful.
      • 19. Vascular grafts: A variety of graft designs are commonly used and these include designs for aortic grafts, dialysis grafts, bypass grafts, arterial grafts for various locations in the peripheral vasculature. All of these will benefit from kink resistance and crush resistance as well as excellent flexibility. Various coatings and surface modifications can be applied.
      • 20. Cholangiography catheters: Catheters used to deliver contrast media to the cystic duct are difficult to use as the conflicting requirements of kink resistance and thin walls make necessary a compromise. This is not the case with the tubing of the invention where the wall can be kept very thin and kink resistant.
      • 21. Vascular embolectomy/thrombectomy catheters: These small diameter catheters have balloons on them for removing clots and in the case of thrombectomy they have a spring body which would make the process of the invention a natural for them. As for the embolectomy catheters, they may benefit from the educed profile, increased inflation lumen and guidewire lumens.
      • 22. Central venous catheters: These catheters are placed near the clavicle and access the superior vena cava through one of the subclavian or innominate veins. They are used for emergency treatment in the case of kidney failure among other uses. These catheters are frequently constructed with two and three lumens and require the ability to extract and return blood quickly. They would benefit from the processes of the invention in that the walls can be made thinner for increased flow or reduced profile or both. They would be almost kink proof and they would have tremendous column strength which would aid in insertion. The processes of the invention would not interfere with any of the commonly used coatings and they may show up better on ultrasound.
  • The foregoing disclosure and description of the invention are illustrative and explanatory thereof, and various changes in the size, shape and materials, as well as in the details of the illustrated construction, may be made without departing from the spirit and scope of the invention. For these reasons, the above description should not be construed as limiting the invention, but should be interpreted as merely exemplary of preferred embodiments.

Claims (66)

1. A medical tubing adapted for insertion into a body tissue or cavity having a length with variable characteristics, comprising:
a plurality of individual, discrete, generally ring-shaped elements arranged in series and fused or bonded together forming a continuous tubular structure.
2. The medical tubing of claim 1, wherein the ring-shaped elements are formed of a thermoplastic material.
3. The medical tubing of claim 1, wherein the ring-shaped elements are formed of a thermoset material.
4. The medical tubing of claim 1, wherein the ring-shaped elements include at least one of plastic rings, metallic rings, un-reinforced plastic rings and metal reinforced plastic rings assembled along the length of the tubular structure to provide variable flexibility and kink-resistance.
5. The medical tubing of claim 1, wherein the tubular structure may be bent, twisted or curved without kinking.
6. The medical tubing of claim 1, wherein the tubular structure has a cross-structure including circular, oval, rectangular, triangular, hexagonal and any geometric shape.
7. The medical tubing of claim 1, wherein the ring-shaped elements have different flexural modulus.
8. The medical tubing of claim 1, wherein the ring-shaped elements include a combination of flexible and rigid ring-shaped elements assembled along different portions or sections of the tubular structure.
9. The medical tubing of claim 4, wherein the metallic rings are coated with plastic and are assembled with alternating elastomeric rings.
10. The medical tubing of claim 8, wherein as the tubular structure is bent, twisted or curved, the rigid ring-shaped elements provide reinforcement to maintain the size and shape of the lumen and the flexible ring-shaped elements operate to stretch and compress to prevent kinking.
11. The medical tubing of claim 1, wherein the ring-shaped elements are metallic and are bonded with a resilient, flexible elastomeric adhesive.
12. The medical tubing of claim 11, wherein the ring-shaped elements have different lengths and are fused closer or further apart to one another depending on the characteristics of a portion or section of the tubing.
13. The medical tubing of claim 1, further comprising a secondary lumen and a pull wire to control the tubular structure.
14. The medical tubing of claim 1, wherein at least one of the ring-shaped elements is truncated to provide a bending bias.
15. The medical tubing of claim 14, wherein the truncated elements comprise of alternating flexible ring-shaped elements and rigid ring-shaped elements.
16. The medical tubing of claim 1, wherein the ring-shaped elements vary in diameter in different portions or sections of the tubular structure.
17. The medical tubing of claim 16, wherein the composition of the ring-shaped elements vary in the different portions or sections of the tubular structure.
18. The medical tubing of claim 17, wherein the ring-shaped elements are assembled in accordance with a preferred modulus within portions or sections of the tubular structure.
19. The medical tubing of claim 1, wherein at least one of the ring-shaped elements is radiopaque.
20. The medical tubing of claim 1, wherein the ring-shaped elements comprise of different colors to operate as indicators along the tubular structure
21. A method of manufacturing a medical tubing having a length with variable characteristics, the medical tubing comprising a plurality of individual, discrete, generally ring-shaped elements arranged in series and fused together to form a continuous tubular structure, the method comprising the steps of:
placing the plurality of ring-shaped elements upon a support member or mandrel in a series arrangement; and
heating the plurality of ring-shaped elements to fuse them together over the support member or mandrel
22. The method of claim 21, further comprising placing the plurality of ring-shaped elements upon a second support member or mandrel before the heating step to subsequently form a second lumen or control tube to the tubular structure.
23. The method of claim 21, further comprising forming a control tube over the assembled ring-shaped elements prior to the heating step.
24. The method of claim 23, wherein the control tube comprises at least one of glass, silicone, heat shrinkable polyolefin, PTFE, FEP, metallic or other tubing that has a higher melting temperature than the assembled ring-shaped elements.
25. A method of manufacturing a medical tubing having a length with variable characteristics, the medical tubing comprising a plurality of individual, discrete, generally ring-shaped elements arranged in series and fused together to form a continuous tubular structure, the method comprising the steps of:
placing the plurality of ring-shaped elements upon a support member or mandrel in a series arrangement; and
fusing the plurality of ring-shaped elements together over the support member or mandrel with a solvent or other chemical compound.
26. The method of claim 25, wherein the fusing step further comprises immersing the ring-shaped elements into the solvent to fuse the elements
27. A method of manufacturing a medical tubing having a length with variable characteristics, the medical tubing comprising a plurality of individual, discrete, generally ring-shaped elements arranged in series and bonded together to form a continuous tubular structure, the method comprising the steps of:
placing the plurality of ring-shaped elements upon a support member or mandrel in a series arrangement; and
bonding together the plurality of ring-shaped elements upon a support member or mandrel with an adhesive.
28. The method of claim 27, wherein the adhesive is photodynamic or heat-activated.
29. The method of claim 21, further comprising coating the tubular structure with an elastomeric adhesive or dispersion.
30. The method of claim 21, wherein the mandrel has a pre-formed curvature for accessing a specific region of a body cavity.
31. The method of claim 21, wherein the mandrel includes a collapsible, inflatable or dissolvable mandrel allowing the tubular structure to vary in diameter and lumen size.
32. The method of claim 31, wherein the mandrel is formed of an electrically dissolvable epoxy resin.
33. The medical tubing of claim 1, wherein the tubing is used as an AV introducer, a urological sheath, a ureteral access sheath, a urethral and bladder access sheath, a kidney access sheath, a ureteral stent, a trocar cannula, a suction/irrigation tubing, an insufflation tubing, a vacuum tubing, a split sheath introducer, a tracheostomy tube, an intubation tube, a gastronomy tube, a jujenostomy tube, an extracorporeal retrograde cholangeopancreatography catheter, an endoscope shaft, a drainage tube, a guide catheter, a hydrocephalic shunt, a guidewire, an angioplasty and dilation balloon, a vascular graft, a cholangiography catheter, a vascular embolectomy/thrombectomy catheter, or a central venous catheter.
34. A method of manufacturing a thin-walled tube, comprising:
coating a wire with a plastic material;
wrapping the coated wire around a mandrel forming a plurality of windings; and
heating the wound coated wire until the plastic material melts and bonds the windings forming a wire-reinforced tube.
35. The method of claim 34, wherein the plastic material comprises at least one of polyurethane, a thermoplastic material and a thermoset material.
36. The method recited of claim 34, wherein the wire comprises at least one of a metallic material and a second plastic material.
37. The method of claim 34, wherein the wire is coated with the plastic material in a coextrusion process.
38. The method of claim 34, wherein the tube has a wall thickness of about 0.015″ or less.
39. The method of claim 34, wherein the tube has an inner diameter that ranges from about 0.026″ to about 0.75″.
40. The method of claim 39, wherein the tolerance on the inner diameter is on the order of 0.001″ or less.
41. The method of claim 34, further comprising compressing the windings as the coated wire is being heated
42. The method of claim 34, further comprising providing a mold to compress the windings.
43. The method of claim 34, further comprising removing the wire-reinforced tube from the mandrel after the tube is cooled.
44. The method of claim 34, wherein the wound coated tube is heated until the plastic material is formed above, below and between all the windings.
45. The method of claim 34, further comprising dipping the tube in a solvent based solution forming an outer layer of the tube.
46. The method of claim 34, wherein the mandrel is tapered to provide the tube with varying diameter throughout the length of the tube.
47. The method of claim 34, further comprising providing a filament comprising a material different from the coating of the wire.
48. The method of claim 47, wherein the coated wire is alternatively wound with the filament around the mandrel.
49. The method of claim 34, wherein the mandrel may be any shape such that the resultant shape of the tube can be removed from the mandrel after the heating step.
50. The method of claim 49, wherein the mandrel is a multiple-part mandrel.
51. A method of manufacturing a kink-resistant thin-walled tube having a length with different characteristics, comprising:
coating a mandrel with a first layer of plastic material;
placing a spring reinforcement over the first layer; and
coating the spring reinforcement with a second layer of plastic material to form a spring-reinforced tube.
52. The method of claim 51, wherein the first layer is formed in an extrusion process.
53. The method of claim 51, wherein the first layer is formed in a molding process.
54. The method of claim 51, wherein the second layer is formed in an extrusion process.
55. The method of claim 51, wherein the second layer is formed in a molding process.
56. The method of claim 51, wherein the spring reinforcement is a pre-wound wire comprising at least one of a metallic material and a second plastic material.
57. The method of claim 51, wherein the spring reinforcement is a wire comprising at least one of a metallic material and a second plastic material wound around the first layer.
58. The method of claim 51, further comprising dipping the tube in a solvent based solution forming an outer layer of the tube.
59. The method of claim 51, wherein the mandrel is tapered to provide the tube with varying diameter throughout the length of the tube.
60. The method of claim 51, wherein the mandrel may be any shape such that the resultant shape of the tube can be removed from the mandrel.
61. The method of claim 60, wherein the mandrel is a multiple-part mandrel.
62. A method of manufacturing a kink-resistant thin-walled tube having a length with different characteristics, comprising:
coating a mandrel with a first layer of plastic material;
placing a spring reinforcement over the first layer; and
dipping the spring-reinforced first layer in a solvent based solution to form a second layer of the tube.
63. The method of claim 62, wherein the second layer is impervious.
64. The method of claim 62, wherein the mandrel is tapered to provide the tube with varying diameter throughout the length of the tube.
65. The method of claim 62, wherein the mandrel may be any shape such that the resultant shape of the tube can be removed from the mandrel.
66. The method of claim 65, wherein the mandrel is a multiple-part mandrel.
US10/766,138 2002-11-15 2004-01-28 Medical tubing having variable characteristics and method of making same Abandoned US20050165366A1 (en)

Priority Applications (19)

Application Number Priority Date Filing Date Title
US10/766,138 US20050165366A1 (en) 2004-01-28 2004-01-28 Medical tubing having variable characteristics and method of making same
US10/832,867 US20050004515A1 (en) 2002-11-15 2004-04-26 Steerable kink resistant sheath
PCT/US2005/001129 WO2005072806A2 (en) 2004-01-28 2005-01-12 Medical tubing having variable characteristics and method of making same
EP05705664A EP1708776A2 (en) 2004-01-28 2005-01-12 Medical tubing having variable characteristics and method of making same
JP2006551162A JP2007524480A (en) 2004-01-28 2005-01-12 Medical tubing having variable characteristics and method of manufacturing the same
CA002552244A CA2552244A1 (en) 2004-01-28 2005-01-12 Medical tubing having variable characteristics and method of making same
AU2005209187A AU2005209187B2 (en) 2004-01-28 2005-01-12 Medical tubing having variable characteristics and method of making same
US11/152,945 US20050256452A1 (en) 2002-11-15 2005-06-14 Steerable vascular sheath
US11/263,876 US20060064054A1 (en) 2002-11-15 2005-11-01 Longitudinal sheath enforcement
US11/695,449 US7850811B2 (en) 2002-11-15 2007-04-02 Steerable kink-resistant sheath
US11/750,235 US20070260225A1 (en) 2002-11-15 2007-05-17 Steerable sheath actuator
US11/750,847 US8529719B2 (en) 2002-11-15 2007-05-18 Method of making medical tubing having variable characteristics using thermal winding
US12/877,245 US8715441B2 (en) 2004-01-28 2010-09-08 Medical tubing having variable characteristics and method of making same
US12/950,782 US8721826B2 (en) 2002-11-15 2010-11-19 Steerable kink-resistant sheath
AU2011200989A AU2011200989B8 (en) 2004-01-28 2011-03-07 Manufacture of medical tubing
US13/965,405 US8691035B2 (en) 2002-11-15 2013-08-13 Method of making medical tubing having variable characteristics using thermal winding
US14/164,954 US9675378B2 (en) 2002-11-15 2014-01-27 Steerable kink-resistant sheath
US14/223,032 US9987460B2 (en) 2004-01-28 2014-03-24 Medical tubing having variable characteristcs and method of making same
US15/949,443 US10765832B2 (en) 2004-01-28 2018-04-10 Medical tubing having variable characteristics and method of making same

Applications Claiming Priority (1)

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US10/766,138 US20050165366A1 (en) 2004-01-28 2004-01-28 Medical tubing having variable characteristics and method of making same

Related Parent Applications (2)

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US10/298,116 Continuation-In-Part US7005026B2 (en) 2002-11-15 2002-11-15 Kink-resistant access sheath and method of making same
US11/319,870 Continuation-In-Part US7534317B2 (en) 2002-11-15 2005-12-28 Kink-resistant access sheath and method of making same

Related Child Applications (5)

Application Number Title Priority Date Filing Date
US10/298,116 Continuation-In-Part US7005026B2 (en) 2002-11-15 2002-11-15 Kink-resistant access sheath and method of making same
US10/832,867 Continuation-In-Part US20050004515A1 (en) 2002-11-15 2004-04-26 Steerable kink resistant sheath
US11/152,945 Continuation-In-Part US20050256452A1 (en) 2002-11-15 2005-06-14 Steerable vascular sheath
US11/750,847 Continuation-In-Part US8529719B2 (en) 2002-11-15 2007-05-18 Method of making medical tubing having variable characteristics using thermal winding
US12/877,245 Division US8715441B2 (en) 2004-01-28 2010-09-08 Medical tubing having variable characteristics and method of making same

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US20050165366A1 true US20050165366A1 (en) 2005-07-28

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US10/766,138 Abandoned US20050165366A1 (en) 2002-11-15 2004-01-28 Medical tubing having variable characteristics and method of making same
US12/877,245 Active 2024-10-14 US8715441B2 (en) 2004-01-28 2010-09-08 Medical tubing having variable characteristics and method of making same
US14/223,032 Active 2026-07-19 US9987460B2 (en) 2004-01-28 2014-03-24 Medical tubing having variable characteristcs and method of making same
US15/949,443 Expired - Lifetime US10765832B2 (en) 2004-01-28 2018-04-10 Medical tubing having variable characteristics and method of making same

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US12/877,245 Active 2024-10-14 US8715441B2 (en) 2004-01-28 2010-09-08 Medical tubing having variable characteristics and method of making same
US14/223,032 Active 2026-07-19 US9987460B2 (en) 2004-01-28 2014-03-24 Medical tubing having variable characteristcs and method of making same
US15/949,443 Expired - Lifetime US10765832B2 (en) 2004-01-28 2018-04-10 Medical tubing having variable characteristics and method of making same

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US (4) US20050165366A1 (en)
EP (1) EP1708776A2 (en)
JP (1) JP2007524480A (en)
AU (2) AU2005209187B2 (en)
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Cited By (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050187467A1 (en) * 2004-01-21 2005-08-25 Martin Kleen Catheter
US20050240278A1 (en) * 2004-04-26 2005-10-27 Peter Aliski Stent improvements
US20050240141A1 (en) * 2004-04-26 2005-10-27 Peter Aliski Stent kidney curl improvements
US20050240280A1 (en) * 2004-04-26 2005-10-27 Peter Aliski Ureteral stent
US20060058862A1 (en) * 2004-09-10 2006-03-16 Scimed Life Systems, Inc. High stretch, low dilation knit prosthetic device and method for making the same
US7217246B1 (en) * 2004-06-17 2007-05-15 Biomet Sports Medicine, Inc. Method and apparatus for retaining a fixation pin to a cannula
US20070208294A1 (en) * 2004-06-17 2007-09-06 Biomet Sports Medicine, Inc. Method And Apparatus For Retaining A Fixation Pin To A Cannula
US20070208300A1 (en) * 2006-03-01 2007-09-06 Applied Medical Resources Corporation Gas insufflation and suction/irrigation tubing
US20070215268A1 (en) * 2002-11-15 2007-09-20 Applied Medical Resources Corporation Method of making medical tubing having variable characteristics using thermal winding
US20080048011A1 (en) * 2006-08-24 2008-02-28 Weller Kip D Shrink tubing jacket construction, and method
WO2008056625A1 (en) 2006-11-07 2008-05-15 Kaneka Corporation Catheter tube for medical use
US20080114435A1 (en) * 2006-03-07 2008-05-15 Med Institute, Inc. Flexible delivery system
EP1925188A2 (en) * 2005-08-08 2008-05-28 Smart Medical Systems Ltd. Balloon guided endoscopy
US20080163870A1 (en) * 2004-10-05 2008-07-10 Takao Kusunoki Tracheostomy Tube
EP1987787A1 (en) 2004-02-19 2008-11-05 Applied Medical Resources Corporation Embolectomy capture sheath
US20080312600A1 (en) * 2007-06-15 2008-12-18 Peter Krulevitch Flexible medical device conduit
US7507218B2 (en) 2004-04-26 2009-03-24 Gyrus Acmi, Inc. Stent with flexible elements
US20090078259A1 (en) * 2007-09-20 2009-03-26 Resmed Limited Retractable tube for cpap
US20090236770A1 (en) * 2008-03-20 2009-09-24 Composite Plastic, Inc. Method of manufacturing reinforced medical tubing
US20100076265A1 (en) * 2008-09-25 2010-03-25 Fujifilm Corporation Endoscope flexible section and endoscope
US20100100045A1 (en) * 2006-11-22 2010-04-22 Applied Medical Resources Corporation Trocar cannula with atramatic tip
US20100100170A1 (en) * 2008-10-22 2010-04-22 Boston Scientific Scimed, Inc. Shape memory tubular stent with grooves
US7803130B2 (en) 2006-01-09 2010-09-28 Vance Products Inc. Deflectable tip access sheath
US20110005661A1 (en) * 2004-01-28 2011-01-13 Applied Medical Resources Corporation Medical Tubing Having Variable Characteristics and Method of Making Same
US20110066105A1 (en) * 2002-11-15 2011-03-17 Applied Medical Resources Corporation Steerable kink-resistant sheath
US20110087198A1 (en) * 2004-11-30 2011-04-14 Carter Brett J Flexible transoral endoscopic gastroesophageal flap valve restoration device and method
US20110118551A1 (en) * 2009-11-14 2011-05-19 SPI Surgical, Inc. Collateral soft tissue protection surgical device
US20120203069A1 (en) * 2009-11-14 2012-08-09 Blake Hannaford Surgical shield for soft tissue protection
US8425550B2 (en) * 2004-12-01 2013-04-23 Boston Scientific Scimed, Inc. Embolic coils
US8641677B2 (en) 2010-01-21 2014-02-04 James T. Rawls Low-profile intravenous catheter device
US8758231B2 (en) 2009-05-14 2014-06-24 Cook Medical Technologies Llc Access sheath with active deflection
US8801736B2 (en) 2010-11-19 2014-08-12 Gil Vardi Percutaneous thrombus extraction device and method
US8986224B2 (en) 2012-07-20 2015-03-24 DePuy Synthes Products, LLC Guidewire with highly flexible tip
US8986201B2 (en) 2009-11-14 2015-03-24 Spiway Llc Surgical tissue protection sheath
US9011326B2 (en) 2009-11-14 2015-04-21 Spiway Llc Soft tissue shield for trans-orbital surgery
EP2766079A4 (en) * 2011-10-14 2015-05-20 Fisher & Paykel Healthcare Ltd Medical tubes and methods of manufacture
WO2015073216A1 (en) * 2013-11-12 2015-05-21 Gyrus Acmi, Inc. Ureteral stents with waveform interlayers and interstitching
US9108017B2 (en) 2011-03-22 2015-08-18 Applied Medical Resources Corporation Method of making tubing have drainage holes
AU2013254919B2 (en) * 2005-08-08 2016-06-16 Smart Medical Systems Ltd. Balloon guided endoscopy
US20160228136A1 (en) * 2012-09-24 2016-08-11 Cook Medical Technologies Llc Medical Devices for the Identification and Treatment of Bodily Passages
US9423058B2 (en) 2014-04-07 2016-08-23 International Business Machines Corporation Formed hose with different fiber-reinforced regions
US9451981B2 (en) 2009-11-14 2016-09-27 Spiway Llc Surgical tissue protection sheath
US20170290492A1 (en) * 2016-04-11 2017-10-12 Canon U.S.A., Inc. Endoscope sheath with integral imaging window
US20180160888A1 (en) * 2016-12-13 2018-06-14 Cook Medical Technologies Llc Imaging mini-scope for endoscope system
US10118334B2 (en) 2016-07-14 2018-11-06 Custom Wire Technologies, Inc. Wire-reinforced tubing and method of making the same
WO2018217105A1 (en) * 2017-05-26 2018-11-29 Fisher And Paykel Healthcare Limited Neonatal flexible and hybrid medical tubes
CN109224247A (en) * 2018-10-26 2019-01-18 大连科万维医疗科技有限公司 A kind of venous cannula of band bending and distortion angle
US20190298460A1 (en) * 2018-03-28 2019-10-03 Auris Health, Inc. Medical instruments with variable bending stiffness profiles
US10898276B2 (en) 2018-08-07 2021-01-26 Auris Health, Inc. Combining strain-based shape sensing with catheter control
US10986984B2 (en) 2013-03-13 2021-04-27 Spiway Llc Surgical tissue protection sheath
CN112914793A (en) * 2021-03-09 2021-06-08 金仕生物科技(常熟)有限公司 Catheter conveying system
US11039735B2 (en) 2013-03-13 2021-06-22 Spiway Llc Surgical tissue protection sheath
CN113056243A (en) * 2018-11-22 2021-06-29 奥林巴斯株式会社 Medical stent and stent delivery device
WO2021195174A1 (en) * 2020-03-26 2021-09-30 The Regents Of The University Of California Salvage device and method for localizing and removing a breast tissue marker clip at surgery after a failed specimen radiogram
US11179212B2 (en) 2018-09-26 2021-11-23 Auris Health, Inc. Articulating medical instruments
US11197977B2 (en) 2017-12-15 2021-12-14 Perfuze Limited Catheters and devices and systems incorporating such catheters
US11213356B2 (en) 2010-09-17 2022-01-04 Auris Health, Inc. Systems and methods for positioning an elongate member inside a body
US11219733B2 (en) 2002-09-09 2022-01-11 Fisher & Paykel Healthcare Limited Limb for breathing circuit
EP3974155A1 (en) * 2020-09-29 2022-03-30 Codan US Corporation Medical coiled tubing
US11350998B2 (en) 2014-07-01 2022-06-07 Auris Health, Inc. Medical instrument having translatable spool
WO2022144631A1 (en) * 2020-12-30 2022-07-07 Medela Holding Ag Enteral feeding tube with polygonal configuration
USD958968S1 (en) 2018-11-28 2022-07-26 Fisher & Paykel Healthcare Limited Breathing tube with mesh
US11413428B2 (en) 2013-03-15 2022-08-16 Auris Health, Inc. Catheter insertion system and method of fabrication
US11419518B2 (en) 2011-07-29 2022-08-23 Auris Health, Inc. Apparatus and methods for fiber integration and registration
US11446469B2 (en) 2016-07-13 2022-09-20 Perfuze Limited High flexibility, kink resistant catheter shaft
US11464586B2 (en) 2009-04-29 2022-10-11 Auris Health, Inc. Flexible and steerable elongate instruments with shape control and support elements
US20220361885A1 (en) * 2014-06-04 2022-11-17 Vascular Development Corp, Llc Low radial force vascular device and method of occlusion
US11511079B2 (en) 2014-07-01 2022-11-29 Auris Health, Inc. Apparatuses and methods for monitoring tendons of steerable catheters
US11583313B1 (en) 2018-12-06 2023-02-21 Spiway Llc Surgical access sheath and methods of use
US11617627B2 (en) 2019-03-29 2023-04-04 Auris Health, Inc. Systems and methods for optical strain sensing in medical instruments
CN115944830A (en) * 2023-03-10 2023-04-11 桐庐精锐医疗器械有限公司 Bendable double-cavity sheath tube and manufacturing method thereof
US11633215B2 (en) * 2016-04-19 2023-04-25 Lsi Solutions, Inc. Needle assembly for pleural space insufflation and methods thereof
US11701192B2 (en) 2016-08-26 2023-07-18 Auris Health, Inc. Steerable catheter with shaft load distributions
US11717147B2 (en) 2019-08-15 2023-08-08 Auris Health, Inc. Medical device having multiple bending sections
US11723636B2 (en) 2013-03-08 2023-08-15 Auris Health, Inc. Method, apparatus, and system for facilitating bending of an instrument in a surgical or medical robotic environment
US11730351B2 (en) 2017-05-17 2023-08-22 Auris Health, Inc. Exchangeable working channel
US11759605B2 (en) 2014-07-01 2023-09-19 Auris Health, Inc. Tool and method for using surgical endoscope with spiral lumens
CN117065118A (en) * 2023-10-16 2023-11-17 四川天府南格尔生物医学有限公司 Multi-cavity tube for bag-type blood separator and manufacturing method thereof
US11819636B2 (en) 2015-03-30 2023-11-21 Auris Health, Inc. Endoscope pull wire electrical circuit

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8535293B2 (en) 2004-04-13 2013-09-17 Gyrus Acmi, Inc. Atraumatic ureteral access sheath
US8235968B2 (en) 2004-04-13 2012-08-07 Gyrus Acmi, Inc. Atraumatic ureteral access sheath
US9505164B2 (en) 2009-12-30 2016-11-29 Schauenburg Technology Se Tapered helically reinforced hose and its manufacture
DE102008022663B4 (en) 2008-05-07 2012-10-31 Schauenburg Hose Technology Gmbh Stretch hose
US9964238B2 (en) 2009-01-15 2018-05-08 Globalmed, Inc. Stretch hose and hose production method
DE102009052688A1 (en) * 2009-11-11 2011-05-12 Invendo Medical Gmbh Endoscope shaft made of a composite tube
JP5659788B2 (en) * 2010-12-28 2015-01-28 住友ベークライト株式会社 catheter
WO2012109462A2 (en) 2011-02-10 2012-08-16 C. R. Bard, Inc. Multi-lumen catheter including an elliptical profile
US9717883B2 (en) 2011-02-10 2017-08-01 C. R. Bard, Inc. Multi-lumen catheter with enhanced flow features
EP2839196B1 (en) 2012-04-18 2018-07-18 Saint-Gobain Performance Plastics Corporation Silicone tubing and method for making and using same
CN104507422B (en) 2013-03-07 2016-08-24 奥林巴斯株式会社 Medical stent
US11077294B2 (en) * 2013-03-13 2021-08-03 Tc1 Llc Sheath assembly for catheter pump
WO2014210427A1 (en) * 2013-06-28 2014-12-31 Gmedix, Inc. Introducer sheath for radial artery access
US10702674B2 (en) 2013-06-28 2020-07-07 Normedix, Inc. Braided catheter assemblies
CN104188619A (en) * 2014-06-27 2014-12-10 深圳市开立科技有限公司 Clamping channel connection pipe, insertion part and endoscope thereof
US9839766B2 (en) * 2014-10-20 2017-12-12 Medtronic Cryocath Lp Centering coiled guide
US10071223B2 (en) 2014-11-05 2018-09-11 Edwards Lifesciences Corporation Compression resistant hose
US20160199553A1 (en) * 2015-01-09 2016-07-14 Luft Industrie Inc. Breast pump adapter
JP7118053B2 (en) * 2016-09-29 2022-08-15 コーニンクレッカ フィリップス エヌ ヴェ Pull wire crown and crown sleeve for catheter assembly
IL265690B2 (en) 2016-09-29 2024-01-01 Rapid Medical Ltd Rotationally torquable endovascular device with actuatable working end
DK3551271T3 (en) 2016-12-08 2023-10-02 Abiomed Inc OVERMOLDING TECHNIQUE FOR DESIGNING PEEL-AWAY INTRODUCING
US20180214658A1 (en) 2017-01-30 2018-08-02 Globalmed Inc. Heated respiratory hose connection
WO2019090351A2 (en) 2017-11-06 2019-05-09 Abiomed, Inc. Peel away hemostasis valve
CA3100259A1 (en) 2018-05-16 2019-11-21 Abiomed, Inc. Peel-away sheath assembly
US11311664B1 (en) 2021-04-12 2022-04-26 Denicia Dread Rankin Shapeable intravenous tubing
WO2023148742A1 (en) * 2022-02-04 2023-08-10 Motus Gi Medical Technologies Ltd. Multi-lumen tubing system for use with an endoscope

Citations (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3113897A (en) * 1958-12-05 1963-12-10 Honningstad Birger Method and apparatus for making fiber reinforced plastic tubes
US3354695A (en) * 1964-07-16 1967-11-28 Pedro A Szente Uniformly tapered transition mandrel
US3585707A (en) * 1966-04-13 1971-06-22 Cordis Corp Method of making tubular products
US3586707A (en) * 1968-11-04 1971-06-22 Us Navy Esterification of mono halo-dinitroethanol and trinitroethanol in the presence of pyridine-n-oxide
US3618613A (en) * 1969-05-19 1971-11-09 Heyer Schulte Corp Antithrombotic intravascular catheter reinforced with nonkinking means
US4619643A (en) * 1983-07-25 1986-10-28 Bai Chao Liang Catheter
US5180376A (en) * 1990-05-01 1993-01-19 Cathco, Inc. Non-buckling thin-walled sheath for the percutaneous insertion of intraluminal catheters
US5429127A (en) * 1991-09-12 1995-07-04 The United States Of America As Represented By The Department Of Health And Human Services Thin wall endotracheal tube
US5472435A (en) * 1993-05-21 1995-12-05 Navarre Biomedical, Ltd. Drainage catheter
US5531721A (en) * 1992-07-02 1996-07-02 Scimed Life Systems, Inc. Multiple member intravascular guide catheter
US5558737A (en) * 1992-05-11 1996-09-24 American Interventional Technologies, Inc. Method of welding a tip to a catheter
US5792116A (en) * 1995-05-17 1998-08-11 Scimed Life Systems, Inc. Catheter having geometrically shaped surface and method of manufacture
US5836925A (en) * 1996-04-03 1998-11-17 Soltesz; Peter P. Catheter with variable flexibility properties and method of manufacture
US5840031A (en) * 1993-07-01 1998-11-24 Boston Scientific Corporation Catheters for imaging, sensing electrical potentials and ablating tissue
US5888436A (en) * 1994-10-28 1999-03-30 Hv Technologies, Inc. Manufacture of variable stiffness microtubing
US5945048A (en) * 1995-03-25 1999-08-31 Ensinger; Wilfried Process and device for extruding polymer melts to form hollow chamber sections
US5947940A (en) * 1997-06-23 1999-09-07 Beisel; Robert F. Catheter reinforced to prevent luminal collapse and tensile failure thereof
US6203732B1 (en) * 1998-07-02 2001-03-20 Intra Therapeutics, Inc. Method for manufacturing intraluminal device
US6464632B1 (en) * 1999-02-13 2002-10-15 James M. Taylor Flexible inner liner for the working channel of an endoscope
US6533770B1 (en) * 1998-01-21 2003-03-18 Heartport, Inc. Cannula and method of manufacture and use
US6533984B2 (en) * 2001-01-04 2003-03-18 Salter Labs Method to produce nasal and oral cannula breathing detection devices
US6540734B1 (en) * 2000-02-16 2003-04-01 Advanced Cardiovascular Systems, Inc. Multi-lumen extrusion tubing
US6669886B1 (en) * 2000-08-03 2003-12-30 Scimed Life Systems, Inc. Reinforced catheter and method of manufacture
US7534317B2 (en) * 2002-11-15 2009-05-19 Applied Medical Resources Corporation Kink-resistant access sheath and method of making same

Family Cites Families (158)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2130586A (en) * 1936-02-18 1938-09-20 Huston Arch Charles Forming roller for tube-winding machines
US2688343A (en) * 1948-04-03 1954-09-07 Hoover Co Flexible hose
US2722263A (en) 1951-08-17 1955-11-01 Gen Motors Corp Method of making flexible air hose
US2688329A (en) * 1953-03-19 1954-09-07 American Cystoscope Makers Inc Catheter
US2701562A (en) * 1953-09-18 1955-02-08 Sidney J Michael Instrument for retracting the walls of an incision
US3226767A (en) * 1961-05-16 1966-01-04 Whitney Blake Co Apparatus for wire coiling
DE1281676B (en) 1964-12-30 1968-10-31 Manfred Hawerkamp Process for the production of pipes and containers from helically wound strip material made of thermoplastic plastics
US3503385A (en) * 1965-09-27 1970-03-31 Cordis Corp Guidable catheter assembly and manipulator therefor
US3617415A (en) 1969-04-23 1971-11-02 Manfred Hawerkamp Method of making hollow reinforced bodies
US3988190A (en) 1970-10-06 1976-10-26 Micropore Insulation Limited Method of forming thermal insulation materials
US3919026A (en) 1970-10-27 1975-11-11 Kuraray Plastics Company Limit Flexible hose manufacturing process
US4010054A (en) * 1971-05-03 1977-03-01 Albert L. Jeffers Thermoplastic filament winding process
US3910808A (en) 1972-08-30 1975-10-07 Steward Plastics Apparatus for making helically wound plastic tubing
US4078957A (en) * 1973-10-03 1978-03-14 Bradt Rexford H Filament winding apparatus and method
US4051844A (en) 1976-05-07 1977-10-04 Medico Developments, Inc. Telescoping neurosurgical scalp retractor
JPS52137715A (en) * 1976-05-13 1977-11-17 Shirou Kanao Flexible hose * having hard resin reinforcing wire
DE2711236C2 (en) * 1976-05-14 1982-09-23 Shiro Osaka Ibaragi Kanao Method and device for the continuous production of a pipe
US4135869A (en) * 1977-12-05 1979-01-23 Dayco Corporation Apparatus for producing a continuous flexible tubular conduit
AU4903579A (en) 1978-07-19 1980-01-24 Dunlop Limited Reinforced tubular articles
DE3145122C2 (en) * 1981-11-13 1984-11-29 Manfred 5210 Troisdorf Hawerkamp Device for producing a pipe or the like from an extruded thermoplastic plastic profile
US4690175A (en) 1981-11-17 1987-09-01 Kabushiki Kaisha Medos Kenkyusho Flexible tube for endoscope
US4470941A (en) * 1982-06-02 1984-09-11 Bioresearch Inc. Preparation of composite surgical sutures
FR2531571A1 (en) 1982-08-06 1984-02-10 Thomson Csf X-RAY TUBE UNIVERSAL FOR STEREOGRAPHY
DE3326858C1 (en) * 1983-07-26 1984-11-08 Reinhard Werner 6057 Dietzenbach Leo Device for producing a wound helix
US4596023A (en) * 1983-08-25 1986-06-17 Complexx Systems, Inc. Balanced biphase transmitter using reduced amplitude of longer pulses
US4605990A (en) * 1984-01-21 1986-08-12 Wilder Joseph R Surgical clip-on light pipe illumination assembly
US4586923A (en) * 1984-06-25 1986-05-06 Cordis Corporation Curving tip catheter
US4818460A (en) * 1986-03-24 1989-04-04 General Electric Company Roller forming of thermoplastic sheet material
US4707906A (en) 1986-03-25 1987-11-24 Posey John T Method of attaching tube to a tube holder
US5509408A (en) * 1987-03-13 1996-04-23 Vital Signs, Inc. Neonatal resuscitation device
US4811743A (en) * 1987-04-21 1989-03-14 Cordis Corporation Catheter guidewire
US4826423A (en) * 1987-08-19 1989-05-02 Chevron Research Company Construction of thermoplastic tubes with tubular ribs by helical winding upon a mandrel
US4820274A (en) * 1987-08-27 1989-04-11 Pradip V. Choksi Medical tube and/or cable holder
US5507751A (en) * 1988-11-09 1996-04-16 Cook Pacemaker Corporation Locally flexible dilator sheath
US4911148A (en) * 1989-03-14 1990-03-27 Intramed Laboratories, Inc. Deflectable-end endoscope with detachable flexible shaft assembly
EP0421650A1 (en) * 1989-10-06 1991-04-10 C.R. Bard, Inc. Multilaminate coiled film catheter construction
US5820591A (en) * 1990-02-02 1998-10-13 E. P. Technologies, Inc. Assemblies for creating compound curves in distal catheter regions
US5254088A (en) 1990-02-02 1993-10-19 Ep Technologies, Inc. Catheter steering mechanism
US5195968A (en) * 1990-02-02 1993-03-23 Ingemar Lundquist Catheter steering mechanism
US6033378A (en) * 1990-02-02 2000-03-07 Ep Technologies, Inc. Catheter steering mechanism
US5273535A (en) 1991-11-08 1993-12-28 Ep Technologies, Inc. Catheter with electrode tip having asymmetric left and right curve configurations
US5891088A (en) * 1990-02-02 1999-04-06 Ep Technologies, Inc. Catheter steering assembly providing asymmetric left and right curve configurations
US5084033A (en) * 1990-03-12 1992-01-28 Minnesota Mining And Manufacturing Company Arterial cannula tip and method of manufacture
JP2987452B2 (en) * 1990-05-17 1999-12-06 オリンパス光学工業株式会社 Endoscope
US5092950A (en) * 1990-08-06 1992-03-03 Phillips Petroleum Company Molding method using a mandrel stabilizer
AU660444B2 (en) * 1991-02-15 1995-06-29 Ingemar H. Lundquist Torquable catheter and method
US5228441A (en) * 1991-02-15 1993-07-20 Lundquist Ingemar H Torquable catheter and method
US5409453A (en) 1992-08-12 1995-04-25 Vidamed, Inc. Steerable medical probe with stylets
US5329923A (en) * 1991-02-15 1994-07-19 Lundquist Ingemar H Torquable catheter
US5315996A (en) * 1991-02-15 1994-05-31 Lundquist Ingemar H Torquable catheter and method
US5304131A (en) * 1991-07-15 1994-04-19 Paskar Larry D Catheter
US5879499A (en) * 1996-06-17 1999-03-09 Heartport, Inc. Method of manufacture of a multi-lumen catheter
JPH0538325A (en) 1991-08-07 1993-02-19 Olympus Optical Co Ltd Endoscope
US5305740A (en) * 1991-09-12 1994-04-26 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Sealing means for endotracheal tubes
US5328467A (en) * 1991-11-08 1994-07-12 Ep Technologies, Inc. Catheter having a torque transmitting sleeve
US5275151A (en) * 1991-12-11 1994-01-04 Clarus Medical Systems, Inc. Handle for deflectable catheter
US5284128A (en) * 1992-01-24 1994-02-08 Applied Medical Resources Corporation Surgical manipulator
USH1261H (en) 1992-05-15 1993-12-07 Gibson Baylor D On-line consolidation of filament wound thermoplastic parts
US5342299A (en) * 1992-07-06 1994-08-30 Catheter Imaging Systems Steerable catheter
US5364351A (en) 1992-11-13 1994-11-15 Ep Technologies, Inc. Catheter steering mechanism
US5441483A (en) * 1992-11-16 1995-08-15 Avitall; Boaz Catheter deflection control
DE69333256T2 (en) 1992-12-04 2004-07-22 C.R. Bard, Inc. Control for use with a catheter with independent distal and proximal controls
US5383852A (en) * 1992-12-04 1995-01-24 C. R. Bard, Inc. Catheter with independent proximal and distal control
US5462527A (en) 1993-06-29 1995-10-31 C.R. Bard, Inc. Actuator for use with steerable catheter
US5611777A (en) * 1993-05-14 1997-03-18 C.R. Bard, Inc. Steerable electrode catheter
USD351652S (en) 1993-06-21 1994-10-18 Ep Technologies, Inc. Steerable medical catheter handle
DE4320962C2 (en) * 1993-06-24 1997-04-17 Osypka Peter Catheter made of a flexible plastic tube
US5562619A (en) * 1993-08-19 1996-10-08 Boston Scientific Corporation Deflectable catheter
US5409469A (en) * 1993-11-04 1995-04-25 Medtronic, Inc. Introducer system having kink resistant splittable sheath
WO1995016141A1 (en) * 1993-12-09 1995-06-15 Devices For Vascular Intervention, Inc. Composite drive shaft
US5509910A (en) * 1994-05-02 1996-04-23 Medtronic, Inc. Method of soft tip attachment for thin walled catheters
US5454061A (en) * 1994-05-27 1995-09-26 Steward Plastics, Inc. Apparatus and method for making flexible tubing with helically wound heating conductor
WO1995033507A1 (en) * 1994-06-03 1995-12-14 Rajko Kenda Catheter and a novel use of a flexible tube
US5512035A (en) * 1994-10-27 1996-04-30 Circon Corporation, A Delaware Corporation Cable compensating mechanism for an endoscope
US6053943A (en) * 1995-12-08 2000-04-25 Impra, Inc. Endoluminal graft with integral structural support and method for making same
US6264684B1 (en) 1995-03-10 2001-07-24 Impra, Inc., A Subsidiary Of C.R. Bard, Inc. Helically supported graft
US5984907A (en) 1995-06-05 1999-11-16 Ep Technologies, Inc. Transition sleeve assembly for catheters
US5863366A (en) * 1995-06-07 1999-01-26 Heartport, Inc. Method of manufacture of a cannula for a medical device
US5702433A (en) 1995-06-27 1997-12-30 Arrow International Investment Corp. Kink-resistant steerable catheter assembly for microwave ablation
US5632734A (en) * 1995-10-10 1997-05-27 Guided Medical Systems, Inc. Catheter shape control by collapsible inner tubular member
WO1997010749A1 (en) * 1995-09-22 1997-03-27 Guided Medical Systems, Inc. Catheter shape control by collapsible inner tubular member
US5980504A (en) * 1996-08-13 1999-11-09 Oratec Interventions, Inc. Method for manipulating tissue of an intervertebral disc
US6007531A (en) 1995-11-21 1999-12-28 Catheter Imaging Systems, Inc. Steerable catheter having disposable module and sterilizable handle and method of connecting same
US5931830A (en) * 1995-12-07 1999-08-03 Sarcos L.C. Hollow coil guide wire apparatus for catheters
US5772641A (en) * 1995-12-12 1998-06-30 Medi-Dyne Inc. Overlapping welds for catheter constructions
US5709665A (en) * 1996-06-05 1998-01-20 Dale Medical Products, Inc. Apparatus and method for holding medical conduits
US5774950A (en) * 1996-08-05 1998-07-07 Stout; Richard A. Tie with clips
US5826576A (en) * 1996-08-08 1998-10-27 Medtronic, Inc. Electrophysiology catheter with multifunction wire and method for making
US5900444A (en) * 1996-10-08 1999-05-04 Zamore; Alan Irradiation conversion of thermoplastic to thermoset polyurethane
US6048329A (en) 1996-12-19 2000-04-11 Ep Technologies, Inc. Catheter distal assembly with pull wires
US6146355A (en) 1996-12-30 2000-11-14 Myelotec, Inc. Steerable catheter
US5904667A (en) * 1997-03-17 1999-05-18 C.R. Bard, Inc. Rotatable control mechanism for steerable catheter
US5827278A (en) 1997-05-20 1998-10-27 Cordis Webster, Inc. Deflectable tip electrode catheter with nylon stiffener and compression coil
US6152912A (en) * 1997-06-10 2000-11-28 Target Therapeutics, Inc. Optimized high performance spiral-wound vascular catheter
US5951539A (en) * 1997-06-10 1999-09-14 Target Therpeutics, Inc. Optimized high performance multiple coil spiral-wound vascular catheter
DE29711559U1 (en) * 1997-07-02 1997-08-21 Howmedica Gmbh Elongated element for the transmission of forces
US6014579A (en) * 1997-07-21 2000-01-11 Cardiac Pathways Corp. Endocardial mapping catheter with movable electrode
US5902287A (en) * 1997-08-20 1999-05-11 Medtronic, Inc. Guiding catheter and method of making same
US6123699A (en) 1997-09-05 2000-09-26 Cordis Webster, Inc. Omni-directional steerable catheter
US5891114A (en) * 1997-09-30 1999-04-06 Target Therapeutics, Inc. Soft-tip high performance braided catheter
US6306235B1 (en) * 1997-10-16 2001-10-23 Nomaco, Inc. Spiral formed products and method of manufacture
US6171277B1 (en) * 1997-12-01 2001-01-09 Cordis Webster, Inc. Bi-directional control handle for steerable catheter
US6273876B1 (en) * 1997-12-05 2001-08-14 Intratherapeutics, Inc. Catheter segments having circumferential supports with axial projection
US6033394A (en) * 1997-12-05 2000-03-07 Intratherapeutics, Inc. Catheter support structure
US5976075A (en) 1997-12-15 1999-11-02 University Of Massachusetts Endoscope deployment apparatus
US6368316B1 (en) * 1998-06-11 2002-04-09 Target Therapeutics, Inc. Catheter with composite stiffener
US6045547A (en) * 1998-06-15 2000-04-04 Scimed Life Systems, Inc. Semi-continuous co-extruded catheter shaft
US6198974B1 (en) * 1998-08-14 2001-03-06 Cordis Webster, Inc. Bi-directional steerable catheter
US6544215B1 (en) * 1998-10-02 2003-04-08 Scimed Life Systems, Inc. Steerable device for introducing diagnostic and therapeutic apparatus into the body
FR2784930B1 (en) * 1998-10-23 2007-09-28 Vetrotex France Sa HOLLOW REVOLUTION BODY OF COMPOSITE MATERIAL AND METHOD OF MANUFACTURING THE SAME
US6221066B1 (en) * 1999-03-09 2001-04-24 Micrus Corporation Shape memory segmented detachable coil
US6228071B1 (en) * 1999-04-16 2001-05-08 Heartport, Inc. Devices and methods for cannulating a blood vessel
US6890329B2 (en) * 1999-06-15 2005-05-10 Cryocath Technologies Inc. Defined deflection structure
EP1068876B1 (en) * 1999-07-16 2004-01-14 Terumo Kabushiki Kaisha Catheter and method of manufacturing the same
US6508804B2 (en) * 1999-07-28 2003-01-21 Scimed Life Systems, Inc. Catheter having continuous lattice and coil reinforcement
US6246914B1 (en) * 1999-08-12 2001-06-12 Irvine Biomedical, Inc. High torque catheter and methods thereof
US6589227B2 (en) * 2000-01-28 2003-07-08 William Cook Europe Aps Endovascular medical device with plurality of wires
JP3915862B2 (en) 2000-02-09 2007-05-16 テルモ株式会社 catheter
CA2400381A1 (en) * 2000-02-18 2001-08-23 Richard M. Beane Devices and methods for warming and cleaning lenses of optical surgical instruments
EP1270031A4 (en) * 2000-03-22 2006-05-24 Kawasumi Lab Medical tube and production method and production device therefor and medical appliance
US6836687B2 (en) 2000-03-31 2004-12-28 Medtronic, Inc. Method and system for delivery of a medical electrical lead within a venous system
US6530897B2 (en) 2000-04-28 2003-03-11 Mahase Nardeo Steerable medical catheter with bendable encapsulated metal spring tip fused to polymeric shaft
US6599265B2 (en) * 2000-07-05 2003-07-29 Visionary Biomedical, Inc. Brake assembly for a steerable cathether
US6916306B1 (en) * 2000-11-10 2005-07-12 Boston Scientific Scimed, Inc. Steerable loop structures for supporting diagnostic and therapeutic elements in contact with body tissue
US6663588B2 (en) 2000-11-29 2003-12-16 C.R. Bard, Inc. Active counterforce handle for use in bidirectional deflectable tip instruments
US6511471B2 (en) * 2000-12-22 2003-01-28 Biocardia, Inc. Drug delivery catheters that attach to tissue and methods for their use
US6979312B2 (en) 2001-04-12 2005-12-27 Biotran Corporation, Inc. Steerable sheath catheters
US6610058B2 (en) 2001-05-02 2003-08-26 Cardiac Pacemakers, Inc. Dual-profile steerable catheter
US6652506B2 (en) 2001-05-04 2003-11-25 Cardiac Pacemakers, Inc. Self-locking handle for steering a single or multiple-profile catheter
US6648875B2 (en) 2001-05-04 2003-11-18 Cardiac Pacemakers, Inc. Means for maintaining tension on a steering tendon in a steerable catheter
ATE412372T1 (en) 2001-05-06 2008-11-15 Stereotaxis Inc CATHETER ADVANCEMENT SYSTEM
US6716207B2 (en) * 2001-05-22 2004-04-06 Scimed Life Systems, Inc. Torqueable and deflectable medical device shaft
CA2457755A1 (en) * 2001-08-16 2003-02-27 Percardia, Inc. Interventional and diagnostic catheter and method for use
US6776765B2 (en) * 2001-08-21 2004-08-17 Synovis Life Technologies, Inc. Steerable stylet
JP4043216B2 (en) * 2001-10-30 2008-02-06 オリンパス株式会社 Stent
AU2003205148A1 (en) * 2002-01-16 2003-09-02 Eva Corporation Catheter hand-piece apparatus and method of using the same
US7025759B2 (en) * 2002-02-04 2006-04-11 Ebi, L.P. Steerable catheter
US20030163082A1 (en) * 2002-02-26 2003-08-28 Mertens Steven P. Lumen weld
US6804866B2 (en) 2002-04-08 2004-10-19 Daniel L. Lemke Cannula clip and associated method of use
US6929766B2 (en) * 2002-06-14 2005-08-16 Edwards Lifesciences Corporation Dispense molding method and apparatus for manufacturing cannulae
US6837847B2 (en) * 2002-06-13 2005-01-04 Usgi Medical, Inc. Shape lockable apparatus and method for advancing an instrument through unsupported anatomy
US20030236493A1 (en) 2002-06-25 2003-12-25 Medamicus, Inc. Articulating handle for a deflectable catheter and method therefor
US20050004515A1 (en) * 2002-11-15 2005-01-06 Hart Charles C. Steerable kink resistant sheath
US20050165366A1 (en) * 2004-01-28 2005-07-28 Brustad John R. Medical tubing having variable characteristics and method of making same
US7228878B2 (en) * 2002-12-04 2007-06-12 Boston Scientific Scimed, Inc. Catheter tubing with improved stress-strain characteristics
FR2850362B1 (en) * 2003-01-24 2005-04-01 Cep Ind POLYPROPYLENE FLEXIBLE TUBE, AND PROCESS FOR OBTAINING SUCH A TUBE
US20040215109A1 (en) 2003-04-23 2004-10-28 Pingleton Edward D. Helical guidewire
USD504175S1 (en) * 2003-05-30 2005-04-19 Brad Westbrook Medical, multiple tube holding device
GB0322511D0 (en) * 2003-09-25 2003-10-29 Angiomed Ag Lining for bodily lumen
US7682358B2 (en) * 2003-10-30 2010-03-23 Medtronic, Inc. Steerable catheter
US7445684B2 (en) * 2003-12-11 2008-11-04 Pursley Matt D Catheter having fibrous reinforcement and method of making the same
US20050159728A1 (en) * 2004-01-15 2005-07-21 Thomas Medical Products, Inc. Steerable sheath
US20050197623A1 (en) 2004-02-17 2005-09-08 Leeflang Stephen A. Variable steerable catheters and methods for using them
US7615032B2 (en) 2004-03-24 2009-11-10 Windcrest Llc Vascular guidewire control apparatus
US7377906B2 (en) 2004-06-15 2008-05-27 Biosense Webster, Inc. Steering mechanism for bi-directional catheter
US7374553B2 (en) 2004-06-24 2008-05-20 Cryocor, Inc. System for bi-directionally controlling the cryo-tip of a cryoablation catheter
US7122020B2 (en) 2004-06-25 2006-10-17 Mogul Enterprises, Inc. Linkage steering mechanism for deflectable catheters
EP2018336B1 (en) 2006-05-18 2018-08-22 Applied Medical Resources Corporation Method of making medical tubing having variable characteristics using thermal winding

Patent Citations (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3113897A (en) * 1958-12-05 1963-12-10 Honningstad Birger Method and apparatus for making fiber reinforced plastic tubes
US3354695A (en) * 1964-07-16 1967-11-28 Pedro A Szente Uniformly tapered transition mandrel
US3585707A (en) * 1966-04-13 1971-06-22 Cordis Corp Method of making tubular products
US3586707A (en) * 1968-11-04 1971-06-22 Us Navy Esterification of mono halo-dinitroethanol and trinitroethanol in the presence of pyridine-n-oxide
US3618613A (en) * 1969-05-19 1971-11-09 Heyer Schulte Corp Antithrombotic intravascular catheter reinforced with nonkinking means
US4619643A (en) * 1983-07-25 1986-10-28 Bai Chao Liang Catheter
US5180376A (en) * 1990-05-01 1993-01-19 Cathco, Inc. Non-buckling thin-walled sheath for the percutaneous insertion of intraluminal catheters
US5429127A (en) * 1991-09-12 1995-07-04 The United States Of America As Represented By The Department Of Health And Human Services Thin wall endotracheal tube
US5558737A (en) * 1992-05-11 1996-09-24 American Interventional Technologies, Inc. Method of welding a tip to a catheter
US5531721A (en) * 1992-07-02 1996-07-02 Scimed Life Systems, Inc. Multiple member intravascular guide catheter
US5472435A (en) * 1993-05-21 1995-12-05 Navarre Biomedical, Ltd. Drainage catheter
US5840031A (en) * 1993-07-01 1998-11-24 Boston Scientific Corporation Catheters for imaging, sensing electrical potentials and ablating tissue
US5888436A (en) * 1994-10-28 1999-03-30 Hv Technologies, Inc. Manufacture of variable stiffness microtubing
US5945048A (en) * 1995-03-25 1999-08-31 Ensinger; Wilfried Process and device for extruding polymer melts to form hollow chamber sections
US5792116A (en) * 1995-05-17 1998-08-11 Scimed Life Systems, Inc. Catheter having geometrically shaped surface and method of manufacture
US5836925A (en) * 1996-04-03 1998-11-17 Soltesz; Peter P. Catheter with variable flexibility properties and method of manufacture
US5947940A (en) * 1997-06-23 1999-09-07 Beisel; Robert F. Catheter reinforced to prevent luminal collapse and tensile failure thereof
US6533770B1 (en) * 1998-01-21 2003-03-18 Heartport, Inc. Cannula and method of manufacture and use
US6203732B1 (en) * 1998-07-02 2001-03-20 Intra Therapeutics, Inc. Method for manufacturing intraluminal device
US6464632B1 (en) * 1999-02-13 2002-10-15 James M. Taylor Flexible inner liner for the working channel of an endoscope
US6540734B1 (en) * 2000-02-16 2003-04-01 Advanced Cardiovascular Systems, Inc. Multi-lumen extrusion tubing
US6669886B1 (en) * 2000-08-03 2003-12-30 Scimed Life Systems, Inc. Reinforced catheter and method of manufacture
US6533984B2 (en) * 2001-01-04 2003-03-18 Salter Labs Method to produce nasal and oral cannula breathing detection devices
US7534317B2 (en) * 2002-11-15 2009-05-19 Applied Medical Resources Corporation Kink-resistant access sheath and method of making same

Cited By (125)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11219733B2 (en) 2002-09-09 2022-01-11 Fisher & Paykel Healthcare Limited Limb for breathing circuit
US8691035B2 (en) 2002-11-15 2014-04-08 Applied Medical Resources Corporation Method of making medical tubing having variable characteristics using thermal winding
US8721826B2 (en) 2002-11-15 2014-05-13 Applied Medical Resources Corporation Steerable kink-resistant sheath
US8529719B2 (en) * 2002-11-15 2013-09-10 Applied Medical Resources Corporation Method of making medical tubing having variable characteristics using thermal winding
US20110066105A1 (en) * 2002-11-15 2011-03-17 Applied Medical Resources Corporation Steerable kink-resistant sheath
US9675378B2 (en) 2002-11-15 2017-06-13 Applied Medical Resources Corporation Steerable kink-resistant sheath
US20070215268A1 (en) * 2002-11-15 2007-09-20 Applied Medical Resources Corporation Method of making medical tubing having variable characteristics using thermal winding
US20050187467A1 (en) * 2004-01-21 2005-08-25 Martin Kleen Catheter
US7957790B2 (en) * 2004-01-21 2011-06-07 Siemens Aktiengesellschaft Catheter
US20110005661A1 (en) * 2004-01-28 2011-01-13 Applied Medical Resources Corporation Medical Tubing Having Variable Characteristics and Method of Making Same
US10765832B2 (en) 2004-01-28 2020-09-08 Applied Medical Resources Corporation Medical tubing having variable characteristics and method of making same
US9987460B2 (en) 2004-01-28 2018-06-05 Applied Medical Resources Corporation Medical tubing having variable characteristcs and method of making same
US8715441B2 (en) 2004-01-28 2014-05-06 Applied Medical Resources Corporation Medical tubing having variable characteristics and method of making same
EP1987787A1 (en) 2004-02-19 2008-11-05 Applied Medical Resources Corporation Embolectomy capture sheath
US7507218B2 (en) 2004-04-26 2009-03-24 Gyrus Acmi, Inc. Stent with flexible elements
US20050240280A1 (en) * 2004-04-26 2005-10-27 Peter Aliski Ureteral stent
US20050240141A1 (en) * 2004-04-26 2005-10-27 Peter Aliski Stent kidney curl improvements
US7470247B2 (en) 2004-04-26 2008-12-30 Gyrus Acmi, Inc. Ureteral stent
US20050240278A1 (en) * 2004-04-26 2005-10-27 Peter Aliski Stent improvements
US20070208294A1 (en) * 2004-06-17 2007-09-06 Biomet Sports Medicine, Inc. Method And Apparatus For Retaining A Fixation Pin To A Cannula
US7828751B2 (en) 2004-06-17 2010-11-09 Biomet Sports Medicine, Llc Method and apparatus for retaining a fixation pin to a cannula
US7217246B1 (en) * 2004-06-17 2007-05-15 Biomet Sports Medicine, Inc. Method and apparatus for retaining a fixation pin to a cannula
US7364587B2 (en) * 2004-09-10 2008-04-29 Scimed Life Systems, Inc. High stretch, low dilation knit prosthetic device and method for making the same
US20060058862A1 (en) * 2004-09-10 2006-03-16 Scimed Life Systems, Inc. High stretch, low dilation knit prosthetic device and method for making the same
US8186349B2 (en) 2004-10-05 2012-05-29 Covidien Ag Tracheostomy tube
US20080163870A1 (en) * 2004-10-05 2008-07-10 Takao Kusunoki Tracheostomy Tube
US20110087198A1 (en) * 2004-11-30 2011-04-14 Carter Brett J Flexible transoral endoscopic gastroesophageal flap valve restoration device and method
US9526500B2 (en) * 2004-11-30 2016-12-27 Endogastric Solutions, Inc. Flexible transoral endoscopic gastroesophageal flap valve restoration device and method
US8425550B2 (en) * 2004-12-01 2013-04-23 Boston Scientific Scimed, Inc. Embolic coils
EP1925188A2 (en) * 2005-08-08 2008-05-28 Smart Medical Systems Ltd. Balloon guided endoscopy
AU2013254919B2 (en) * 2005-08-08 2016-06-16 Smart Medical Systems Ltd. Balloon guided endoscopy
EP1925188B1 (en) * 2005-08-08 2016-10-05 Smart Medical Systems Ltd. Balloon guided endoscopy
US7803130B2 (en) 2006-01-09 2010-09-28 Vance Products Inc. Deflectable tip access sheath
US20070208300A1 (en) * 2006-03-01 2007-09-06 Applied Medical Resources Corporation Gas insufflation and suction/irrigation tubing
US9962537B2 (en) 2006-03-01 2018-05-08 Applied Medical Resources Corporation Gas insufflation and suction/irrigation tubing
US20080114435A1 (en) * 2006-03-07 2008-05-15 Med Institute, Inc. Flexible delivery system
WO2007137184A3 (en) * 2006-05-18 2008-03-13 Applied Med Resources Method of making medical tubing having variable characteristics using thermal winding
WO2007137184A2 (en) 2006-05-18 2007-11-29 Applied Medical Resources Corporation Method of making medical tubing having variable characteristics using thermal winding
US20080048011A1 (en) * 2006-08-24 2008-02-28 Weller Kip D Shrink tubing jacket construction, and method
WO2008056625A1 (en) 2006-11-07 2008-05-15 Kaneka Corporation Catheter tube for medical use
US20100057052A1 (en) * 2006-11-07 2010-03-04 Kaneka Corporation Medical Catheter Tube
US20100100045A1 (en) * 2006-11-22 2010-04-22 Applied Medical Resources Corporation Trocar cannula with atramatic tip
US10485578B2 (en) 2006-11-22 2019-11-26 Applied Medical Resources Corporation Trocar cannula with atraumatic tip
US8945058B2 (en) 2006-11-22 2015-02-03 Applied Medical Resources Corporation Trocar cannula with atraumatic tip
US20080308523A1 (en) * 2007-06-15 2008-12-18 Peter Krulevitch Method for manufacturing flexible medical device conduit
US20080312582A1 (en) * 2007-06-15 2008-12-18 Peter Krulevitch Method for inserting a flexible medical device conduit
US20080312600A1 (en) * 2007-06-15 2008-12-18 Peter Krulevitch Flexible medical device conduit
US10034995B2 (en) 2007-09-20 2018-07-31 Resmed Limited Retractable tube for CPAP
US20090078259A1 (en) * 2007-09-20 2009-03-26 Resmed Limited Retractable tube for cpap
US20090236770A1 (en) * 2008-03-20 2009-09-24 Composite Plastic, Inc. Method of manufacturing reinforced medical tubing
US8066926B2 (en) 2008-03-20 2011-11-29 Fogarty Terence M Method of manufacturing reinforced medical tubing
US20100076265A1 (en) * 2008-09-25 2010-03-25 Fujifilm Corporation Endoscope flexible section and endoscope
US20100100170A1 (en) * 2008-10-22 2010-04-22 Boston Scientific Scimed, Inc. Shape memory tubular stent with grooves
US9980806B2 (en) 2008-10-22 2018-05-29 Boston Scientific Scimed, Inc. Shape memory tubular stent with grooves
US11464586B2 (en) 2009-04-29 2022-10-11 Auris Health, Inc. Flexible and steerable elongate instruments with shape control and support elements
US8758231B2 (en) 2009-05-14 2014-06-24 Cook Medical Technologies Llc Access sheath with active deflection
US9011326B2 (en) 2009-11-14 2015-04-21 Spiway Llc Soft tissue shield for trans-orbital surgery
US9451981B2 (en) 2009-11-14 2016-09-27 Spiway Llc Surgical tissue protection sheath
US20120203069A1 (en) * 2009-11-14 2012-08-09 Blake Hannaford Surgical shield for soft tissue protection
US8986201B2 (en) 2009-11-14 2015-03-24 Spiway Llc Surgical tissue protection sheath
US20110118551A1 (en) * 2009-11-14 2011-05-19 SPI Surgical, Inc. Collateral soft tissue protection surgical device
US8641677B2 (en) 2010-01-21 2014-02-04 James T. Rawls Low-profile intravenous catheter device
US9861791B2 (en) 2010-01-21 2018-01-09 James T. Rawls Low-profile intravenous catheter device
US11213356B2 (en) 2010-09-17 2022-01-04 Auris Health, Inc. Systems and methods for positioning an elongate member inside a body
US10039560B2 (en) 2010-11-19 2018-08-07 Gil Vardi Percutaneous thrombus extraction device
US11096701B2 (en) 2010-11-19 2021-08-24 Gil Vardi Percutaneous thrombus extraction device and method
US11571227B2 (en) 2010-11-19 2023-02-07 Gil Vardi Percutaneous thrombus extraction device and method
US8801736B2 (en) 2010-11-19 2014-08-12 Gil Vardi Percutaneous thrombus extraction device and method
US9108017B2 (en) 2011-03-22 2015-08-18 Applied Medical Resources Corporation Method of making tubing have drainage holes
US11419518B2 (en) 2011-07-29 2022-08-23 Auris Health, Inc. Apparatus and methods for fiber integration and registration
AU2012321401B2 (en) * 2011-10-14 2017-09-14 Fisher & Paykel Healthcare Limited Medical tubes and methods of manufacture
EP2766079A4 (en) * 2011-10-14 2015-05-20 Fisher & Paykel Healthcare Ltd Medical tubes and methods of manufacture
EP4074358A1 (en) * 2011-10-14 2022-10-19 Fisher & Paykel Healthcare Limited Medical tubes and methods of manufacture
US10828455B2 (en) 2011-10-14 2020-11-10 Fisher & Paykel Healthcare Limited Medical tubes and methods of manufacture
US8986224B2 (en) 2012-07-20 2015-03-24 DePuy Synthes Products, LLC Guidewire with highly flexible tip
US10426925B2 (en) * 2012-09-24 2019-10-01 Cook Medical Technologies Llc Medical devices for the identification and treatment of bodily passages
US20160228136A1 (en) * 2012-09-24 2016-08-11 Cook Medical Technologies Llc Medical Devices for the Identification and Treatment of Bodily Passages
US11723636B2 (en) 2013-03-08 2023-08-15 Auris Health, Inc. Method, apparatus, and system for facilitating bending of an instrument in a surgical or medical robotic environment
US10986984B2 (en) 2013-03-13 2021-04-27 Spiway Llc Surgical tissue protection sheath
US11039735B2 (en) 2013-03-13 2021-06-22 Spiway Llc Surgical tissue protection sheath
US11413428B2 (en) 2013-03-15 2022-08-16 Auris Health, Inc. Catheter insertion system and method of fabrication
US10080641B2 (en) 2013-11-12 2018-09-25 Gyrus Acmi, Inc. Ureteral stents with waveform interlayers and interstitching
EP3912670A1 (en) * 2013-11-12 2021-11-24 Gyrus ACMI, Inc. Ureteral stents with waveform interlayers and interstitching
WO2015073216A1 (en) * 2013-11-12 2015-05-21 Gyrus Acmi, Inc. Ureteral stents with waveform interlayers and interstitching
US9242079B2 (en) 2013-11-12 2016-01-26 Gyrus Acmi, Inc. Ureteral stents with waveform interlayers and interstitching
US9746109B2 (en) 2014-04-07 2017-08-29 International Business Machines Corporation Fabricating formed hose with different fiber-reinforced regions
US10234061B2 (en) 2014-04-07 2019-03-19 Internation Business Machines Corporation Formed hose with different fiber-reinforced regions
US9423058B2 (en) 2014-04-07 2016-08-23 International Business Machines Corporation Formed hose with different fiber-reinforced regions
US9890878B2 (en) 2014-04-07 2018-02-13 International Business Machines Corporation Formed hose with different fiber-reinforced regions
US20220361885A1 (en) * 2014-06-04 2022-11-17 Vascular Development Corp, Llc Low radial force vascular device and method of occlusion
US11759605B2 (en) 2014-07-01 2023-09-19 Auris Health, Inc. Tool and method for using surgical endoscope with spiral lumens
US11511079B2 (en) 2014-07-01 2022-11-29 Auris Health, Inc. Apparatuses and methods for monitoring tendons of steerable catheters
US11350998B2 (en) 2014-07-01 2022-06-07 Auris Health, Inc. Medical instrument having translatable spool
US11819636B2 (en) 2015-03-30 2023-11-21 Auris Health, Inc. Endoscope pull wire electrical circuit
US10842352B2 (en) * 2016-04-11 2020-11-24 Canon U.S.A., Inc. Endoscope sheath with integral imaging window
US20170290492A1 (en) * 2016-04-11 2017-10-12 Canon U.S.A., Inc. Endoscope sheath with integral imaging window
US11633215B2 (en) * 2016-04-19 2023-04-25 Lsi Solutions, Inc. Needle assembly for pleural space insufflation and methods thereof
US11446469B2 (en) 2016-07-13 2022-09-20 Perfuze Limited High flexibility, kink resistant catheter shaft
US10118334B2 (en) 2016-07-14 2018-11-06 Custom Wire Technologies, Inc. Wire-reinforced tubing and method of making the same
US11701192B2 (en) 2016-08-26 2023-07-18 Auris Health, Inc. Steerable catheter with shaft load distributions
US20180160888A1 (en) * 2016-12-13 2018-06-14 Cook Medical Technologies Llc Imaging mini-scope for endoscope system
US11730351B2 (en) 2017-05-17 2023-08-22 Auris Health, Inc. Exchangeable working channel
CN110997049A (en) * 2017-05-26 2020-04-10 费雪派克医疗保健有限公司 Flexible mixed medical tube for neonate
WO2018217105A1 (en) * 2017-05-26 2018-11-29 Fisher And Paykel Healthcare Limited Neonatal flexible and hybrid medical tubes
US11918745B2 (en) 2017-05-26 2024-03-05 Fisher & Paykel Healthcare Limited Neonatal flexible and hybrid medical tubes
US11197977B2 (en) 2017-12-15 2021-12-14 Perfuze Limited Catheters and devices and systems incorporating such catheters
US11109920B2 (en) * 2018-03-28 2021-09-07 Auris Health, Inc. Medical instruments with variable bending stiffness profiles
US20190298460A1 (en) * 2018-03-28 2019-10-03 Auris Health, Inc. Medical instruments with variable bending stiffness profiles
US10898276B2 (en) 2018-08-07 2021-01-26 Auris Health, Inc. Combining strain-based shape sensing with catheter control
US11779400B2 (en) 2018-08-07 2023-10-10 Auris Health, Inc. Combining strain-based shape sensing with catheter control
US11779421B2 (en) 2018-09-26 2023-10-10 Auris Health, Inc. Articulating medical instruments
US11179212B2 (en) 2018-09-26 2021-11-23 Auris Health, Inc. Articulating medical instruments
CN109224247A (en) * 2018-10-26 2019-01-18 大连科万维医疗科技有限公司 A kind of venous cannula of band bending and distortion angle
CN113056243A (en) * 2018-11-22 2021-06-29 奥林巴斯株式会社 Medical stent and stent delivery device
USD958968S1 (en) 2018-11-28 2022-07-26 Fisher & Paykel Healthcare Limited Breathing tube with mesh
US11583313B1 (en) 2018-12-06 2023-02-21 Spiway Llc Surgical access sheath and methods of use
US11617627B2 (en) 2019-03-29 2023-04-04 Auris Health, Inc. Systems and methods for optical strain sensing in medical instruments
US11717147B2 (en) 2019-08-15 2023-08-08 Auris Health, Inc. Medical device having multiple bending sections
WO2021195174A1 (en) * 2020-03-26 2021-09-30 The Regents Of The University Of California Salvage device and method for localizing and removing a breast tissue marker clip at surgery after a failed specimen radiogram
US11779748B2 (en) 2020-09-29 2023-10-10 Codan Us Corporation Medical coiled tubing
EP3974155A1 (en) * 2020-09-29 2022-03-30 Codan US Corporation Medical coiled tubing
WO2022144631A1 (en) * 2020-12-30 2022-07-07 Medela Holding Ag Enteral feeding tube with polygonal configuration
CN112914793A (en) * 2021-03-09 2021-06-08 金仕生物科技(常熟)有限公司 Catheter conveying system
CN115944830A (en) * 2023-03-10 2023-04-11 桐庐精锐医疗器械有限公司 Bendable double-cavity sheath tube and manufacturing method thereof
CN117065118A (en) * 2023-10-16 2023-11-17 四川天府南格尔生物医学有限公司 Multi-cavity tube for bag-type blood separator and manufacturing method thereof

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US8715441B2 (en) 2014-05-06
US20110005661A1 (en) 2011-01-13
US9987460B2 (en) 2018-06-05
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WO2005072806A3 (en) 2006-02-02
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AU2011200989B8 (en) 2013-10-24
EP1708776A2 (en) 2006-10-11
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US10765832B2 (en) 2020-09-08

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