US20020161434A1 - Moveable intraocular lens - Google Patents

Moveable intraocular lens Download PDF

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Publication number
US20020161434A1
US20020161434A1 US10/173,380 US17338002A US2002161434A1 US 20020161434 A1 US20020161434 A1 US 20020161434A1 US 17338002 A US17338002 A US 17338002A US 2002161434 A1 US2002161434 A1 US 2002161434A1
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United States
Prior art keywords
intraocular lens
eye
optic
end region
movement
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Abandoned
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US10/173,380
Inventor
Stephen Laguette
Alan Lang
Robert Glick
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Johnson and Johnson Surgical Vision Inc
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Allergan Sales LLC
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Priority to US10/173,380 priority Critical patent/US20020161434A1/en
Publication of US20020161434A1 publication Critical patent/US20020161434A1/en
Assigned to ADVANCE MEDICAL OTPICS, INC. reassignment ADVANCE MEDICAL OTPICS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: ALLERGAN PHARMACEUTICALS, INC., ALLERGAN SALES, LLC, ALLERGAN, INC., AMERICAN HOSPITAL SUPPLY CORPORATION, HEYER-SCHULTE CORP., INNOVATIVE SURGICAL PRODUCTS, INC.
Abandoned legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16Intraocular lenses
    • A61F2/1613Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16Intraocular lenses
    • A61F2/1613Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A61F2/1624Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus having adjustable focus; power activated variable focus means, e.g. mechanically or electrically by the ciliary muscle or from the outside
    • A61F2/1629Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus having adjustable focus; power activated variable focus means, e.g. mechanically or electrically by the ciliary muscle or from the outside for changing longitudinal position, i.e. along the visual axis when implanted
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16Intraocular lenses
    • A61F2/1613Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A61F2/1654Diffractive lenses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/0077Special surfaces of prostheses, e.g. for improving ingrowth
    • A61F2002/009Special surfaces of prostheses, e.g. for improving ingrowth for hindering or preventing attachment of biological tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16Intraocular lenses
    • A61F2002/16965Lens includes ultraviolet absorber
    • A61F2002/1699Additional features not otherwise provided for

Definitions

  • the present invention is directed to intraocular lenses (IOLs). More particularly, the invention relates to IOLs which are adapted to provide accommodating movement in the eye.
  • IOLs intraocular lenses
  • the human eye includes an anterior chamber between the cornea and iris, a posterior chamber, defined by a capsular bag, containing a crystalline lens, a ciliary muscle, a vitreous chamber behind the lens containing the vitreous humor, and a retina at the rear of this chamber.
  • the human eye has a natural accommodation ability. The contraction and relaxation of the ciliary muscle provides the eye with near and distant vision, respectively. This ciliary muscle action shapes the natural crystalline lens to the appropriate optical configuration for focusing light rays entering the eye on the retina.
  • a conventional, monofocal IOL can be placed in the posterior chamber.
  • Such a conventional IOL has very limited, if any, accommodating ability.
  • the wearer of such an IOL continues to require the ability to view both near and far (distant) objects.
  • Corrective spectacles may be employed as a useful solution.
  • multifocal IOLs without accommodating movement have been used to provide near/far vision correction.
  • the posterior wall of the capsular bag is subjected to a substantial degree of stretching when the lens is in the posterior-most position.
  • One problem that exists with such IOLs is that they often cannot move sufficiently to obtain the desired accommodation.
  • IOLs adapted for accommodating movement which can achieve an acceptable amount of accommodation with reduced risk of damaging the capsular bag.
  • the present accommodating IOLs take advantage of the ability of the eye to move the present IOLs sufficiently, for example, as a result of zonular tension acting on the capsular bag of the eye.
  • the present IOLs effectively reduce detrimental stretching of the capsular bag even with the lens in the posterior-most position in the eye.
  • the present IOLs allow the capsular bag to retain sufficient elasticity to change its diameter, in particular its equatorial diameter, sufficiently to provide the desired degree of accommodation.
  • the present lenses preferably are configured to advantageously increase the amount of accommodating movement achieved as a result of elasticity of the capsular bag and the action of the ciliary muscle.
  • the present IOLs are straightforward in construction, can be implanted or inserted into the eye using systems and procedures which are well known in the art and function effectively with little or no additional treatments or medications being required.
  • the present IOLs comprise an optic adapted to focus light toward a retina of an eye; and a movement assembly coupled to the optic and adapted to cooperate with the eye to effect accommodating movement of the optic.
  • the movement assembly preferably circumscribes, more preferably substantially completely circumscribes, the optic and comprises a member including a proximal end portion coupled to the optic and a distal end portion extending away from the optic and adapted to contact the capsular bag of the eye.
  • the movement assembly circumscribing the optic very effectively enhances the degree to which the elasticity of the capsular bag and the action of the ciliary muscle acting on the zonules and the capsular bag causes accommodating movement of the optic.
  • the movement assembly is adapted to cooperate with the eye to effect accommodating movement of the optic upon radial, for example, diametrical, compression by the capsular bag of the eye.
  • the optic has a far vision correction power, more preferably a far vision correction power for infinity, in the unaccommodated state.
  • the movement assembly is positioned relative to the optic so that, with the IOL at rest, for example, in the eye, the optic vaults anteriorly of the distal end region of the movement assembly.
  • This anterior vaulting feature reduces the risk of detrimental posterior stretching of the capsular bag with the IOL located in the posterior-most position in the eye.
  • the optic of the IOL may contact the capsular bag but, because of the anterior vaulting, causes a reduced amount of posterior stretching of the capsular bag relative to a similar IOL without the anterior vaulting feature located in the posterior-most position.
  • the anterior vaulting feature in addition, is effective in at least assisting in increased amounts of accommodating movement, again relative to a similar IOL without such anterior vaulting feature.
  • the present IOLs preferably are sized to fit the capsular bag of the eye in the unaccommodated state substantially without stretching the capsular bag. Proper sizing of the IOL facilitates enhanced accommodating movement of the IOL in the eye.
  • such IOLs preferably provide an amount of axial movement anteriorly in the eye in the range of about 0.5 or about 1.5 mm to about 2.0 mm with about 1.0 mm of reduction in the equatorial diameter of the capsular bag.
  • the optic of the IOL has a diameter in the range of about 3.5 mm to about 7 mm, more preferably about 5 mm to about 6 mm.
  • the overall diameter of the present IOLs preferably is in the range of about 8 mm to about 11 mm or about 12 mm.
  • the movement assembly may be adapted to be affixed to the capsular bag of the eye including the IOL.
  • the movement assembly preferably is sufficiently flexible to facilitate movement of the optic relative to the distal end region of the movement assembly being acted upon by the eye.
  • the movement assembly may include a hinge assembly positioned proximally of the distal end region of the movement assembly. Such hinge assembly is effective in facilitating the accommodating movement of the optic in the eye.
  • the hinge assembly may include one or more regions of reduced thickness, for example, circumscribing the optic. These reduced thickness regions are effective to provide a desired degree of flexibility to the movement assembly.
  • the movement assembly may have a minimum thickness at the proximal end region and a maximum thickness at the distal end region. In one embodiment, the movement assembly includes no hole or holes passing through, for example, axially through, the movement assembly.
  • the distal end region of the movement assembly includes a peripheral edge configured to inhibit cell growth from the eye in front of or in back of the intraocular lens.
  • the movement assembly has an anterior face and an opposing posterior face with the peripheral edge being between these two faces. The intersection of the peripheral edge and at least one of the anterior face and the posterior face forms a peripheral corner located at a discontinuity between the peripheral edge and the intersecting face. Cell growth from the eye in front of or in back of the movement assembly preferably is more inhibited relative to a substantially identical intraocular lens without the peripheral corner.
  • methods for inserting an IOL in an eye comprise providing an IOL in accordance with the present invention, as described herein.
  • the IOL is placed into the eye, for example, in the capsular bag of the eye, using equipment and techniques which are conventional and well known in the art.
  • the IOL is placed in the unaccommodated position in the eye.
  • the placing step is effective so that the optic of the IOL is radially, e.g., diametrically, compressed by the capsular bag, for example, by the elasticity of the capsular bag, of the eye to effect accommodating movement of the optic of the IOL.
  • No treatments or medications for example, to paralyze the ciliary muscle to facilitate fibrosis or otherwise influence the position of the IOL in the eye, are required.
  • the optic is deformed prior to being placed into the eye.
  • the IOL in cooperation with the eye, provides the mammal or human wearing the IOL with near focus accommodation.
  • the IOL provides the mammal or human wearing the IOL with far vision correction.
  • FIG. 1 is a fragmentary sectional view of an eye in which an IOL in accordance with the present invention has been implanted, with the lens being located in a posterior rest position in the eye.
  • FIG. 2 is a fragmentary sectional view of an eye in which the IOL of FIG. 3 has been implanted, with the lens being located in an intermediate position in the eye.
  • FIG. 3 is a fragmentary sectional view of an eye in which the IOL of FIG. 3 has been implanted with the lens being located in an anterior position in the eye.
  • FIG. 4 is a perspective view of the IOL shown in FIG. 1 in the rest position.
  • FIG. 5 is a cross-sectional view taken generally along line 5 - 5 of FIG. 4.
  • FIG. 6 is a partial cross-sectional view of an alternate embodiment of an IOL in accordance with the present invention.
  • FIG. 7 is a partial cross-sectional view of an another embodiment of an IOL in accordance with the present invention.
  • FIG. 8 is a cross-sectional view taken generally along arc 8 - 8 of FIG. 5.
  • FIG. 9 is a cross-sectional view taken generally along arc 9 - 9 of FIG. 6.
  • FIG. 10 is a cross-sectional view taken generally along arc 10 - 10 of FIG. 7.
  • an IOL according to the present invention shown generally at 10 , includes a lens body or optic 12 .
  • member 14 Extending radially outwardly from lens body 12 is member 14 , which fully or completely circumscribes the lens body.
  • Member 14 which includes no through holes, has a proximal end portion 16 which is coupled to the optic 12 at optic periphery 18 .
  • Member 14 extends radially outwardly to a distal end region 20 including a peripheral edge 22 , which extends between the anterior surface 24 and the posterior surface 26 of member 14 .
  • member 14 can be, and preferably is, integral or unitary with the optic 12 .
  • Member 14 extends outwardly from optic 12 sufficiently so that the distal end region 20 is in contact with the inner peripheral wall of the posterior capsular bag when the IOL 10 is implanted in the eye.
  • the optic 12 is positioned or vaulted anteriorly relative to the distal end region 20 of member 14 .
  • the anterior surface 23 of optic 12 is anterior of the anterior surface 24 of member 14 at distal end region 20 and/or the posterior surface 25 of the optic is anterior of the posterior surface 26 of the member at the distal end region.
  • the optic 12 may be constructed of rigid biocompatible materials, such as polymethyl methacrylate (PMMA), or flexible, deformable materials, such as silicone polymeric materials, acrylic polymeric materials, hydrogel polymeric materials and the like, which enable the optic 12 to be rolled or folded for insertion through a small incision into the eye.
  • PMMA polymethyl methacrylate
  • deformable materials such as silicone polymeric materials, acrylic polymeric materials, hydrogel polymeric materials and the like, which enable the optic 12 to be rolled or folded for insertion through a small incision into the eye.
  • the optic 12 as shown is a refractive lens body
  • the present IOLs can include a diffractive lens body and such embodiment is included within the scope of the present invention.
  • Optic 12 is prescribed for the wearer of IOL 10 with a baseline or far (distance) diopter power for infinity.
  • the member 14 is integral (unitary) with and circumscribes the optic 12 .
  • member 14 can be mechanically or otherwise physically coupled to optic 12 .
  • the member 14 may only partially circumscribe the optic, and such embodiment is included within the scope of the present invention.
  • the member 14 may be constructed of the same or different biocompatible materials as optic 12 , and preferably is made of polymeric materials, such as polypropylene, silicone polymeric materials acrylic polymeric materials and the like. Member 14 has sufficient strength or rigidity to be effective to transfer the force from the capsular bag of the eye to move the optic 12 axially in the eye to effect accommodation.
  • Such strength or rigidity is enhanced by employing a solid member 14 , that is a member having no axial through hole or holes, for example, perforations.
  • the member 14 preferably is deformable, in much the same manner as optic 12 is deformable, to facilitate passing IOL 10 through a small incision into the eye.
  • the material or materials of construction from which member 14 is made are chosen to provide the member with the desired mechanical properties, e.g., strength, and/or deformability, to meet the needs of the particular application involved.
  • the IOL 10 can be inserted into the capsular bag of a mammalian eye using conventional equipment and techniques, for example, after the natural crystalline lens of the eye is removed, using a phacoemulsification technique.
  • the IOL 10 preferably is rolled or folded prior to insertion into the eye, and is inserted through a small incision, on the order of about 3.2 mm, into the eye and is located in the eye 40 , as shown in FIGS. 1 to 3 .
  • the IOL 10 in the eye 40 is located in a posterior position in the capsular bag 42 with zonules 42 under tension.
  • the configuration of IOL 10 in particular with regard to the anterior vaulting of the optic 12 , allows the IOL to be in the posterior-most position in the eye with the optic in close proximity to or even contacting the posterior capsule 44 .
  • the IOL 10 does not cause substantial stretching of the posterior capsule 44 .
  • the natural elasticity of the capsular bag preferably is substantially maintained and is effective in providing accommodating movement of the IOL 10 .
  • the IOL 10 is positioned so that the optic 12 , in cooperation with the eye 40 , can be moved axially, substantially along optical axis 39 in the eye to provide accommodation.
  • the distal end region 20 of member 14 is in contact with the interior wall 46 of the capsular bag 44 . Over time, the distal end region 20 of the member 14 may become affixed to the capsular bag 44 , although this is not necessary to obtain benefits in accordance with the present invention.
  • the member 14 in the eye 40 , cooperates with the eye to effect accommodating movement of the optic 12 , preferably upon radial, such as diametrical, compression of the IOL 10 by the elastic capsular bag 44 of the eye.
  • the IOL 10 should be sized to facilitate the movement of the optic 12 in response to the action of ciliary muscle 48 and zonules 42 .
  • the optic 12 if the optic 12 is too large, the amount of accommodating movement will be unduly restricted. Of course, if the IOL 10 is too small, the optic 12 will be ineffective to focus light on the retina of the eye 40 , may cause glare and/or the flexible member 14 may not cooperate with the eye to effect the desired amount of accommodating movement.
  • the optic 12 preferably has a diameter in the range of about 3.5 mm to about 7 mm, more preferably in the range of about 5 mm to about 6 mm. and the IOL has an overall maximum diameter, with the member 14 in the unflexed or at rest state, in the range of about 8 mm to about 11 mm or about 12 mm.
  • the zonules 42 and the ciliary muscle 48 are effective to reduce or increase the equatorial diameter of the capsular bag 44 and thereby move the IOL 10 included in the bag anteriorly or posteriorly, respectively.
  • relaxation of the ciliary muscle 46 causes the zonules 44 to increase the equatorial diameter of the capsular bag 44 , resulting in IOL 10 moving posteriorly into a posterior position, as shown in FIG. 1.
  • IOL 10 With IOL 10 in the posterior position, as shown in FIG. 1, far away or distant objects are brought into focus.
  • the ciliary muscle 48 contracts or constricts causing a reduction in the tension of the zonules 42 , which allows the equatorial diameter of the capsular bag 44 to reduce.
  • the IOL 10 is thereby diametrically compressed and moved anteriorly, as shown in FIG. 3.
  • the caspular bag 44 has or retain sufficient elasticity to act directly on the IOL 10 to comrpess the IOL 10 and move the IOL 10 anteriorly.
  • This action of ciliary muscle 48 , zonules 42 and capsular bag 44 causes member 14 to flex or vault into an anterior position, shown in FIG.
  • This anterior vaulting action of member 14 together with the anterior vaulting of optic 12 , increases the amount of positive (near) accommodating movement of optic 12 relative to a similar IOL in which the member does not include an intermediate portion capable of flexing or vaulting.
  • IOL 10 achieves increased accommodating movement because of such flexing or vaulting.
  • This anterior movement of optic 12 provides near focus accommodation to allow the near object to be viewed.
  • the present IOL 10 has the ability, in cooperation with the eye, to move both posteriorly and anteriorly in the eye, to provide for both distance focus and near focus, respectively.
  • This movement of IOL 10 advantageously occurs in response to action of the ciliary muscle 48 , zonules 42 and capsular bag 44 which action is substantially similar to that which effects accommodation in an eye having a natural crystalline lens.
  • the ciliary muscle 48 , zonules 42 and capsular bag 44 require little, if any, retraining to function in accordance with the present invention.
  • the member 14 as described herein, preferably is effective to facilitate or even enhance or accentuate the axial movement of the IOL 10 caused by the action of the ciliary muscle 48 , zonules 44 and capsular bag 44 to provide increased degree of accommodation.
  • IOL 10 is such that the amount of positive or near accommodation preferably is in the range of about 1 to about 2.5 or about 3.5 diopters or more.
  • the configuration and sizing of IOL 10 is effective to provide an amount of axial movement anteriorly in the eye in a range of about 0.5 mm or about 1.5 mm to about 2.0 mm or about 2.5 mm with about 1 mm of reduction in the equatorial diameter of the capsular bag 44 caused by the action of the ciliary muscle 48 and zonules 42 .
  • This amount of axial movement is based on an initial position of the IOL 10 in the posterior position, as shown in FIG. 1.
  • peripheral edge 22 with the anterior face 24 and posterior face 26 of member 14 also are at substantially 90° relative to the optical axis of the IOL 10 .
  • These sharp corners 41 and 43 which involve substantial discontinuities, rather than continuous or curved transitions, between the peripheral edge 22 and anterior face 24 and posterior face 26 , respectively, have been found to be effective in inhibiting or retarding cell migration or growth from the eye onto or over the optic 12 of the IOL 10 .
  • FIGS. 6 and 9 illustrate an additional IOL, shown generally at 110 , in accordance with the present invention. Except as expressly described herein, additional IOL 110 is structured and functions similarly to IOL 10 . Components of IOL 110 which correspond to components of IOL 10 are indicated by the same reference numeral increased by 100 .
  • member 114 is configured in a tapered manner so that the proximal end region 116 has a minimum thickness and distal end region 120 has a maximum thickness.
  • This tapered configuration of member 114 is effective in a manner similar to region 30 of IOL 10 to cause flexing of the IOL 110 , particularly with the equatorial diameter of the capsular bag being reduced.
  • This tapered configuration of member 114 can be considered substantially equivalent to the member 14 including the reduced thickness region 30 . Both of these configurations can be looked at as including a hinge located in proximity to the proximal end regions 16 and 116 of members 14 and 114 , respectively.
  • peripheral edge 122 includes a first portion 70 which is concave relative to the optical axis of IOL 110 .
  • Peripheral 122 also includes a second portion 72 which is convex relative to the optical axis of IOL 110 .
  • the curvature of the peripheral edges of the present IOLs can be relatively complex.
  • the peripheral edge 122 intersects anterior face 124 of member 114 at peripheral corner 74 at an angle of about 90°.
  • peripheral edge 122 intersects the posterior face 126 of member 114 at posterior peripheral corner 76 at an angle of about 90°.
  • the peripheral anterior corner 74 and peripheral posterior corner 76 are effective in inhibiting or retarding cell migration or growth from the eye onto or over the optic 112 .
  • peripheral edge configurations may be employed to inhibit or retard the migration of cells from the eye onto the optic of the IOL.
  • the peripheral edge can include a champhered portion intersecting the anterior face of the member, preferably at a discontinuity, an intermediate portion extending outwardly and posteriorly from the champhered portion at an angle other than parallel to the central optical axis of the optic, and a flat or posterior portion extending from the intermediate portion and intersecting the posterior face of the member, preferably at a discontinuity.
  • This flat portion advantageously is parallel to the central optical axis of the optic.
  • FIGS. 7 and 10 illustrate an alternate embodiment of an IOL in accordance with the present invention.
  • This IOL is shown generally at 210 .
  • IOL 210 is structures and functions substantially similarly to IOL 10 .
  • Components of IOL 210 which correspond to components of IOL 10 are indicated by the same reference numeral increased by 200 .
  • member 214 includes an area 80 of reduced thickness in proximity to the proximal end region 216 of member 214 .
  • the difference between area 80 and area 30 of member 14 involves the straight walls of area 80 versus the rounded or curved wall of area 30 .
  • member 214 includes region 80 which has straight, mutually angled (intersecting) side walls in cross-section (FIG. 6), as opposed to the rounded side wall of region 30 .
  • Region 80 operates to provide the hinge feature to member 214 and IOL 210 .
  • Such feature facilitates the axial movement of the optic 212 .
  • IOL 210 moves in response to the action of the ciliary muscle 48 and zonules 42 in much the same manner as does IOL 10 .
  • the regions 30 and 80 can be considered hinges.
  • other configurations for example, other hinge configurations, which provide the desired degree of movement to the members, can be used and are included within the scope of the present invention.
  • IOL 210 includes a peripheral edge 222 which is concave throughout relative to the optical axis of the IOL 210 .
  • the intersections of peripheral edge 210 and the anterior face 224 of member 214 occurs at an anterior peripheral corner 82 similarly the intersection between the peripheral edge 222 and the posterior face 226 of member 214 occurs at a posterior peripheral corner 84 .
  • the configuration of peripheral edge 222 and the peripheral corners 82 and 84 inhibit or retard the migration or growth or cells from the eye onto the optic 212 of IOL 210 ,
  • the present invention provides accommodating IOLs and methods for obtaining accommodating using such IOLs.
  • the present IOLs are configured to reduce the stretching of the capsular bag, to maintain the elasticity and/or integrity of the capsular bag, to enhance the effectiveness of the eye, in particular the ciliary muscle and zonules in effecting accommodating movement of the IOL in the eye and to inhibit or retard cell growth from the eye onto the object of the IOL.

Abstract

Intraocular lenses include an optic adapted to focus light toward a retina of an eye and a movement assembly coupled to the optic. In one embodiment, the optic has a far vision correction power and the movement assembly is adapted to cooperate with the eye to effect accommodating movement of the optic, preferably upon radial compression by a capsular bag of the eye. The optic preferably vaults anteriorly relative to the movement assembly. The movement assembly preferably circumscribes the optic and includes a member having a proximal end portion coupled to the optic and a distal end portion extending away from the optic and adapted to contact a capsular bag of the eye.

Description

    CROSS REFERENCE TO RELATED APPLICATION
  • This application claims the benefit of U.S. Provisional Application 60/131/913 filed Apr. 30, 1999 and entitled MOVEABLE INTRAOCULAR LENS.[0001]
  • BACKGROUND OF THE INVENTION
  • The present invention is directed to intraocular lenses (IOLs). More particularly, the invention relates to IOLs which are adapted to provide accommodating movement in the eye. [0002]
  • The human eye includes an anterior chamber between the cornea and iris, a posterior chamber, defined by a capsular bag, containing a crystalline lens, a ciliary muscle, a vitreous chamber behind the lens containing the vitreous humor, and a retina at the rear of this chamber. The human eye has a natural accommodation ability. The contraction and relaxation of the ciliary muscle provides the eye with near and distant vision, respectively. This ciliary muscle action shapes the natural crystalline lens to the appropriate optical configuration for focusing light rays entering the eye on the retina. [0003]
  • After the natural crystalline lens is removed, for example, because of cataract or other condition, a conventional, monofocal IOL can be placed in the posterior chamber. Such a conventional IOL has very limited, if any, accommodating ability. However, the wearer of such an IOL continues to require the ability to view both near and far (distant) objects. Corrective spectacles may be employed as a useful solution. Recently, multifocal IOLs without accommodating movement have been used to provide near/far vision correction. [0004]
  • Attempts have been made to provide IOLs with accommodating movement along the optical axis of the eye as an alternative to shape changing. Examples of such attempts are set forth in Levy U.S. Pat. No. 4,409,691 and several patents to Cumming, including U.S. Pat. Nos. 5,674,282 and 5,496,366. The disclosure of each of these patents is incorporated herein by reference. These lenses are biased to be located in the posterior-most position in the eye under rest or resting conditions. When near focus is desired, the ciliary muscle contracts and the lens moves forwardly (positive accommodation). In the absence of ciliary muscle contraction, the lens moves rearwardly to its posterior-most resting position. Because of this posterior bias and the configuration of the lens, the posterior wall of the capsular bag is subjected to a substantial degree of stretching when the lens is in the posterior-most position. One problem that exists with such IOLs is that they often cannot move sufficiently to obtain the desired accommodation. [0005]
  • It would be advantageous to provide IOLs adapted for accommodating movement which can achieve an acceptable amount of accommodation with reduced risk of damaging the capsular bag. [0006]
  • SUMMARY OF THE INVENTION
  • New accommodating IOLs have been discovered. The present accommodating IOLs take advantage of the ability of the eye to move the present IOLs sufficiently, for example, as a result of zonular tension acting on the capsular bag of the eye. The present IOLs effectively reduce detrimental stretching of the capsular bag even with the lens in the posterior-most position in the eye. Moreover, the present IOLs allow the capsular bag to retain sufficient elasticity to change its diameter, in particular its equatorial diameter, sufficiently to provide the desired degree of accommodation. In addition, the present lenses preferably are configured to advantageously increase the amount of accommodating movement achieved as a result of elasticity of the capsular bag and the action of the ciliary muscle. The present IOLs are straightforward in construction, can be implanted or inserted into the eye using systems and procedures which are well known in the art and function effectively with little or no additional treatments or medications being required. [0007]
  • In general, the present IOLs comprise an optic adapted to focus light toward a retina of an eye; and a movement assembly coupled to the optic and adapted to cooperate with the eye to effect accommodating movement of the optic. The movement assembly preferably circumscribes, more preferably substantially completely circumscribes, the optic and comprises a member including a proximal end portion coupled to the optic and a distal end portion extending away from the optic and adapted to contact the capsular bag of the eye. The movement assembly circumscribing the optic very effectively enhances the degree to which the elasticity of the capsular bag and the action of the ciliary muscle acting on the zonules and the capsular bag causes accommodating movement of the optic. Preferably, the movement assembly is adapted to cooperate with the eye to effect accommodating movement of the optic upon radial, for example, diametrical, compression by the capsular bag of the eye. [0008]
  • In a very useful embodiment, the optic has a far vision correction power, more preferably a far vision correction power for infinity, in the unaccommodated state. Thus, with the IOL located in the posterior-most position, distant objects can be easily and accurately viewed. [0009]
  • Preferably, the movement assembly is positioned relative to the optic so that, with the IOL at rest, for example, in the eye, the optic vaults anteriorly of the distal end region of the movement assembly. This anterior vaulting feature reduces the risk of detrimental posterior stretching of the capsular bag with the IOL located in the posterior-most position in the eye. Thus, in this posterior-most position, the optic of the IOL may contact the capsular bag but, because of the anterior vaulting, causes a reduced amount of posterior stretching of the capsular bag relative to a similar IOL without the anterior vaulting feature located in the posterior-most position. The anterior vaulting feature, in addition, is effective in at least assisting in increased amounts of accommodating movement, again relative to a similar IOL without such anterior vaulting feature. [0010]
  • The present IOLs preferably are sized to fit the capsular bag of the eye in the unaccommodated state substantially without stretching the capsular bag. Proper sizing of the IOL facilitates enhanced accommodating movement of the IOL in the eye. [0011]
  • Because of the size and configuration of the present IOLs, such IOLs preferably provide an amount of axial movement anteriorly in the eye in the range of about 0.5 or about 1.5 mm to about 2.0 mm with about 1.0 mm of reduction in the equatorial diameter of the capsular bag. [0012]
  • In one very useful embodiment, the optic of the IOL has a diameter in the range of about 3.5 mm to about 7 mm, more preferably about 5 mm to about 6 mm. The overall diameter of the present IOLs preferably is in the range of about 8 mm to about 11 mm or about 12 mm. [0013]
  • The movement assembly may be adapted to be affixed to the capsular bag of the eye including the IOL. [0014]
  • The movement assembly preferably is sufficiently flexible to facilitate movement of the optic relative to the distal end region of the movement assembly being acted upon by the eye. The movement assembly may include a hinge assembly positioned proximally of the distal end region of the movement assembly. Such hinge assembly is effective in facilitating the accommodating movement of the optic in the eye. The hinge assembly may include one or more regions of reduced thickness, for example, circumscribing the optic. These reduced thickness regions are effective to provide a desired degree of flexibility to the movement assembly. The movement assembly may have a minimum thickness at the proximal end region and a maximum thickness at the distal end region. In one embodiment, the movement assembly includes no hole or holes passing through, for example, axially through, the movement assembly. [0015]
  • In a very useful embodiment, the distal end region of the movement assembly includes a peripheral edge configured to inhibit cell growth from the eye in front of or in back of the intraocular lens. In a particularly useful embodiment, the movement assembly has an anterior face and an opposing posterior face with the peripheral edge being between these two faces. The intersection of the peripheral edge and at least one of the anterior face and the posterior face forms a peripheral corner located at a discontinuity between the peripheral edge and the intersecting face. Cell growth from the eye in front of or in back of the movement assembly preferably is more inhibited relative to a substantially identical intraocular lens without the peripheral corner. [0016]
  • In a further broad aspect of the present invention, methods for inserting an IOL in an eye are provided. Such methods comprise providing an IOL in accordance with the present invention, as described herein. The IOL is placed into the eye, for example, in the capsular bag of the eye, using equipment and techniques which are conventional and well known in the art. The IOL is placed in the unaccommodated position in the eye. In one embodiment, the placing step is effective so that the optic of the IOL is radially, e.g., diametrically, compressed by the capsular bag, for example, by the elasticity of the capsular bag, of the eye to effect accommodating movement of the optic of the IOL. No treatments or medications, for example, to paralyze the ciliary muscle to facilitate fibrosis or otherwise influence the position of the IOL in the eye, are required. Preferably, the optic is deformed prior to being placed into the eye. Once the IOL is placed in the eye, and after a normal period of recovery from the surgical procedure, the IOL, in cooperation with the eye, provides the mammal or human wearing the IOL with near focus accommodation. In the unaccommodated state, the IOL provides the mammal or human wearing the IOL with far vision correction. [0017]
  • Any and all features described herein and combinations of such features are included within the scope of the present invention provided that the features of any such combination are not mutually inconsistent. [0018]
  • Additional aspects and advantages of the present invention are set forth in the following description and claims, particularly when considered in conjunction with the accompanying drawings in which like parts bear like reference numerals.[0019]
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • FIG. 1 is a fragmentary sectional view of an eye in which an IOL in accordance with the present invention has been implanted, with the lens being located in a posterior rest position in the eye. [0020]
  • FIG. 2 is a fragmentary sectional view of an eye in which the IOL of FIG. 3 has been implanted, with the lens being located in an intermediate position in the eye. [0021]
  • FIG. 3 is a fragmentary sectional view of an eye in which the IOL of FIG. 3 has been implanted with the lens being located in an anterior position in the eye. [0022]
  • FIG. 4 is a perspective view of the IOL shown in FIG. 1 in the rest position. [0023]
  • FIG. 5 is a cross-sectional view taken generally along line [0024] 5-5 of FIG. 4.
  • FIG. 6 is a partial cross-sectional view of an alternate embodiment of an IOL in accordance with the present invention. [0025]
  • FIG. 7 is a partial cross-sectional view of an another embodiment of an IOL in accordance with the present invention. [0026]
  • FIG. 8 is a cross-sectional view taken generally along arc [0027] 8-8 of FIG. 5.
  • FIG. 9 is a cross-sectional view taken generally along arc [0028] 9-9 of FIG. 6.
  • FIG. 10 is a cross-sectional view taken generally along arc [0029] 10-10 of FIG. 7.
  • DETAILED DESCRIPTION OF THE DRAWINGS
  • Referring now to FIGS. [0030] 1 to 5, an IOL according to the present invention, shown generally at 10, includes a lens body or optic 12. Extending radially outwardly from lens body 12 is member 14, which fully or completely circumscribes the lens body. Member 14, which includes no through holes, has a proximal end portion 16 which is coupled to the optic 12 at optic periphery 18. Member 14 extends radially outwardly to a distal end region 20 including a peripheral edge 22, which extends between the anterior surface 24 and the posterior surface 26 of member 14. Although it is not essential, member 14 can be, and preferably is, integral or unitary with the optic 12. Member 14 extends outwardly from optic 12 sufficiently so that the distal end region 20 is in contact with the inner peripheral wall of the posterior capsular bag when the IOL 10 is implanted in the eye. As best seen in FIG. 5, when IOL 10 is at rest, the optic 12 is positioned or vaulted anteriorly relative to the distal end region 20 of member 14. In other words, the anterior surface 23 of optic 12 is anterior of the anterior surface 24 of member 14 at distal end region 20 and/or the posterior surface 25 of the optic is anterior of the posterior surface 26 of the member at the distal end region.
  • The optic [0031] 12 may be constructed of rigid biocompatible materials, such as polymethyl methacrylate (PMMA), or flexible, deformable materials, such as silicone polymeric materials, acrylic polymeric materials, hydrogel polymeric materials and the like, which enable the optic 12 to be rolled or folded for insertion through a small incision into the eye. Although the optic 12 as shown is a refractive lens body, the present IOLs can include a diffractive lens body and such embodiment is included within the scope of the present invention.
  • [0032] Optic 12 is prescribed for the wearer of IOL 10 with a baseline or far (distance) diopter power for infinity.
  • The [0033] member 14, as shown, is integral (unitary) with and circumscribes the optic 12. Alternately, member 14 can be mechanically or otherwise physically coupled to optic 12. The member 14 may only partially circumscribe the optic, and such embodiment is included within the scope of the present invention. The member 14 may be constructed of the same or different biocompatible materials as optic 12, and preferably is made of polymeric materials, such as polypropylene, silicone polymeric materials acrylic polymeric materials and the like. Member 14 has sufficient strength or rigidity to be effective to transfer the force from the capsular bag of the eye to move the optic 12 axially in the eye to effect accommodation. Such strength or rigidity is enhanced by employing a solid member 14, that is a member having no axial through hole or holes, for example, perforations. The member 14 preferably is deformable, in much the same manner as optic 12 is deformable, to facilitate passing IOL 10 through a small incision into the eye. The material or materials of construction from which member 14 is made are chosen to provide the member with the desired mechanical properties, e.g., strength, and/or deformability, to meet the needs of the particular application involved.
  • The [0034] IOL 10 can be inserted into the capsular bag of a mammalian eye using conventional equipment and techniques, for example, after the natural crystalline lens of the eye is removed, using a phacoemulsification technique. The IOL 10 preferably is rolled or folded prior to insertion into the eye, and is inserted through a small incision, on the order of about 3.2 mm, into the eye and is located in the eye 40, as shown in FIGS. 1 to 3.
  • The [0035] IOL 10 in the eye 40, as shown in FIG. 1, is located in a posterior position in the capsular bag 42 with zonules 42 under tension. The configuration of IOL 10, in particular with regard to the anterior vaulting of the optic 12, allows the IOL to be in the posterior-most position in the eye with the optic in close proximity to or even contacting the posterior capsule 44. However, in the posterior-most position the IOL 10 does not cause substantial stretching of the posterior capsule 44. The natural elasticity of the capsular bag preferably is substantially maintained and is effective in providing accommodating movement of the IOL 10.
  • The [0036] IOL 10 is positioned so that the optic 12, in cooperation with the eye 40, can be moved axially, substantially along optical axis 39 in the eye to provide accommodation.
  • The [0037] distal end region 20 of member 14 is in contact with the interior wall 46 of the capsular bag 44. Over time, the distal end region 20 of the member 14 may become affixed to the capsular bag 44, although this is not necessary to obtain benefits in accordance with the present invention. The member 14, in the eye 40, cooperates with the eye to effect accommodating movement of the optic 12, preferably upon radial, such as diametrical, compression of the IOL 10 by the elastic capsular bag 44 of the eye.
  • The [0038] IOL 10 should be sized to facilitate the movement of the optic 12 in response to the action of ciliary muscle 48 and zonules 42. For example, if the optic 12 is too large, the amount of accommodating movement will be unduly restricted. Of course, if the IOL 10 is too small, the optic 12 will be ineffective to focus light on the retina of the eye 40, may cause glare and/or the flexible member 14 may not cooperate with the eye to effect the desired amount of accommodating movement. If the IOL 10 is to be included in an adult human eye, the optic 12 preferably has a diameter in the range of about 3.5 mm to about 7 mm, more preferably in the range of about 5 mm to about 6 mm. and the IOL has an overall maximum diameter, with the member 14 in the unflexed or at rest state, in the range of about 8 mm to about 11 mm or about 12 mm.
  • The [0039] zonules 42 and the ciliary muscle 48 are effective to reduce or increase the equatorial diameter of the capsular bag 44 and thereby move the IOL 10 included in the bag anteriorly or posteriorly, respectively. Thus, relaxation of the ciliary muscle 46 causes the zonules 44 to increase the equatorial diameter of the capsular bag 44, resulting in IOL 10 moving posteriorly into a posterior position, as shown in FIG. 1.
  • With [0040] IOL 10 in the posterior position, as shown in FIG. 1, far away or distant objects are brought into focus.
  • If a near object is to be viewed, the [0041] ciliary muscle 48 contracts or constricts causing a reduction in the tension of the zonules 42, which allows the equatorial diameter of the capsular bag 44 to reduce. The IOL 10 is thereby diametrically compressed and moved anteriorly, as shown in FIG. 3. Without wishing to limit the invention to any particular theory of operation, it is believed that the caspular bag 44 has or retain sufficient elasticity to act directly on the IOL 10 to comrpess the IOL 10 and move the IOL 10 anteriorly. This action of ciliary muscle 48, zonules 42 and capsular bag 44 causes member 14 to flex or vault into an anterior position, shown in FIG. 3, which enhances or increases (amplifies) the amount of anterior movement of optic 12. This anterior vaulting action of member 14, together with the anterior vaulting of optic 12, increases the amount of positive (near) accommodating movement of optic 12 relative to a similar IOL in which the member does not include an intermediate portion capable of flexing or vaulting. In effect, IOL 10 achieves increased accommodating movement because of such flexing or vaulting. This anterior movement of optic 12 provides near focus accommodation to allow the near object to be viewed.
  • The [0042] present IOL 10 has the ability, in cooperation with the eye, to move both posteriorly and anteriorly in the eye, to provide for both distance focus and near focus, respectively. This movement of IOL 10 advantageously occurs in response to action of the ciliary muscle 48, zonules 42 and capsular bag 44 which action is substantially similar to that which effects accommodation in an eye having a natural crystalline lens. Thus, the ciliary muscle 48, zonules 42 and capsular bag 44 require little, if any, retraining to function in accordance with the present invention. The member 14, as described herein, preferably is effective to facilitate or even enhance or accentuate the axial movement of the IOL 10 caused by the action of the ciliary muscle 48, zonules 44 and capsular bag 44 to provide increased degree of accommodation.
  • [0043] IOL 10 is such that the amount of positive or near accommodation preferably is in the range of about 1 to about 2.5 or about 3.5 diopters or more. Looked at from another perspective, the configuration and sizing of IOL 10 is effective to provide an amount of axial movement anteriorly in the eye in a range of about 0.5 mm or about 1.5 mm to about 2.0 mm or about 2.5 mm with about 1 mm of reduction in the equatorial diameter of the capsular bag 44 caused by the action of the ciliary muscle 48 and zonules 42. This amount of axial movement is based on an initial position of the IOL 10 in the posterior position, as shown in FIG. 1.
  • As best shown in FIG. 8, the intersections of [0044] peripheral edge 22 with the anterior face 24 and posterior face 26 of member 14 also are at substantially 90° relative to the optical axis of the IOL 10. These sharp corners 41 and 43, which involve substantial discontinuities, rather than continuous or curved transitions, between the peripheral edge 22 and anterior face 24 and posterior face 26, respectively, have been found to be effective in inhibiting or retarding cell migration or growth from the eye onto or over the optic 12 of the IOL 10.
  • FIGS. 6 and 9 illustrate an additional IOL, shown generally at [0045] 110, in accordance with the present invention. Except as expressly described herein, additional IOL 110 is structured and functions similarly to IOL 10. Components of IOL 110 which correspond to components of IOL 10 are indicated by the same reference numeral increased by 100.
  • One primary difference between [0046] IOL 110 and IOL 10 relates to the configuration of member 114. In particular, as best shown in FIG. 6, member 114 is configured in a tapered manner so that the proximal end region 116 has a minimum thickness and distal end region 120 has a maximum thickness. This tapered configuration of member 114 is effective in a manner similar to region 30 of IOL 10 to cause flexing of the IOL 110, particularly with the equatorial diameter of the capsular bag being reduced. This tapered configuration of member 114 can be considered substantially equivalent to the member 14 including the reduced thickness region 30. Both of these configurations can be looked at as including a hinge located in proximity to the proximal end regions 16 and 116 of members 14 and 114, respectively.
  • An additional difference between [0047] IOL 110 and IOL 10 has to do with the configuration of peripheral edge 122.
  • With specific reference to FIG. 9, [0048] peripheral edge 122 includes a first portion 70 which is concave relative to the optical axis of IOL 110. Peripheral 122 also includes a second portion 72 which is convex relative to the optical axis of IOL 110. Thus, the curvature of the peripheral edges of the present IOLs, for example, peripheral edge 122 of IOL 110, can be relatively complex. In addition, the peripheral edge 122 intersects anterior face 124 of member 114 at peripheral corner 74 at an angle of about 90°. Similarly, peripheral edge 122 intersects the posterior face 126 of member 114 at posterior peripheral corner 76 at an angle of about 90°. The peripheral anterior corner 74 and peripheral posterior corner 76 are effective in inhibiting or retarding cell migration or growth from the eye onto or over the optic 112.
  • Other peripheral edge configurations may be employed to inhibit or retard the migration of cells from the eye onto the optic of the IOL. For example, the peripheral edge can include a champhered portion intersecting the anterior face of the member, preferably at a discontinuity, an intermediate portion extending outwardly and posteriorly from the champhered portion at an angle other than parallel to the central optical axis of the optic, and a flat or posterior portion extending from the intermediate portion and intersecting the posterior face of the member, preferably at a discontinuity. This flat portion advantageously is parallel to the central optical axis of the optic. [0049]
  • FIGS. 7 and 10 illustrate an alternate embodiment of an IOL in accordance with the present invention. This IOL is shown generally at [0050] 210. Except as expressly described herein, IOL 210 is structures and functions substantially similarly to IOL 10. Components of IOL 210 which correspond to components of IOL 10 are indicated by the same reference numeral increased by 200.
  • One primary difference between [0051] IOL 210 and IOL 10 relates to the configuration of member 214. In particular, as best shown in FIG. 7, member 214 includes an area 80 of reduced thickness in proximity to the proximal end region 216 of member 214. The difference between area 80 and area 30 of member 14 involves the straight walls of area 80 versus the rounded or curved wall of area 30. Thus, member 214 includes region 80 which has straight, mutually angled (intersecting) side walls in cross-section (FIG. 6), as opposed to the rounded side wall of region 30.
  • [0052] Region 80 operates to provide the hinge feature to member 214 and IOL 210. Such feature facilitates the axial movement of the optic 212. In addition, IOL 210 moves in response to the action of the ciliary muscle 48 and zonules 42 in much the same manner as does IOL 10.
  • The [0053] regions 30 and 80 can be considered hinges. Of course, other configurations, for example, other hinge configurations, which provide the desired degree of movement to the members, can be used and are included within the scope of the present invention.
  • In addition, [0054] IOL 210 includes a peripheral edge 222 which is concave throughout relative to the optical axis of the IOL 210. The intersections of peripheral edge 210 and the anterior face 224 of member 214 occurs at an anterior peripheral corner 82 similarly the intersection between the peripheral edge 222 and the posterior face 226 of member 214 occurs at a posterior peripheral corner 84. The configuration of peripheral edge 222 and the peripheral corners 82 and 84 inhibit or retard the migration or growth or cells from the eye onto the optic 212 of IOL 210,
  • The present invention provides accommodating IOLs and methods for obtaining accommodating using such IOLs. The present IOLs are configured to reduce the stretching of the capsular bag, to maintain the elasticity and/or integrity of the capsular bag, to enhance the effectiveness of the eye, in particular the ciliary muscle and zonules in effecting accommodating movement of the IOL in the eye and to inhibit or retard cell growth from the eye onto the object of the IOL. These benefits are obtained with IOLs which are straightforward in construction, relatively easy to manufacture and insert into the eye and which are effective to provide accommodation for long term use. [0055]
  • While this invention has been described with respect to various specific examples and embodiments, it is to be understood that the invention is not limited thereto and that it can be variously practiced within the scope of the following claims. [0056]

Claims (30)

What is claimed is:
1. An intraocular lens comprising:
an optic adapted to focus light toward a retina of an eye, the optic having a far vision correction power;
a movement assembly coupled to the optic and adapted to cooperate with the eye to effect accommodating movement of the optic upon radial compression by a capsular bag of the eye, the movement assembly circumscribes the optic and comprises a member including a proximal end region coupled to the optic and a distal end region extending away from the optic and adapted to contact the capsular bag of the eye.
2. The intraocular lens of claim 1 wherein the movement assembly is positioned relative to the optic so that, with the intraocular lens at rest, the optic vaults anteriorly of the distal end region of the movement assembly.
3. The intraocular lens of claim 1 wherein the optic has a far vision correction power for infinity in the unaccommodated state.
4. The intraocular lens of claim 2 wherein the distal end region of the movement assembly includes a peripheral edge configured to inhibit cell growth from the eye in front of or in back of the intraocular lens.
5. The intraocular lens of claim 1 sized to provide an amount of axial movement anteriorly in the eye in a range of about 0.5 mm to about 2.0 mm with about 1 mm of reduction in an equatorial diameter of the capsular bag.
6. The intraocular lens of claim 1 which is deformable for insertion through a small incision in the eye.
7. The intraocular lens of claim 1 wherein the movement assembly is sufficiently flexible to facilitate movement of the optic relative to its distal end region upon being acted upon by the eye.
8. The intraocular lens of claim 7 wherein the movement assembly has a minimum thickness at the proximal end region and a maximum thickness at the distal end region.
9. The intraocular lens of claim 1 wherein the movement assembly includes a hinge assembly positioned proximally of the distal end region.
10. The intraocular lens of claim 9 wherein the hinge assembly includes a region of reduced thickness circumscribing the optic.
11. An intraocular lens comprising:
an optic adapted to focus light toward a retina of an eye; and
a movement assembly coupled to the optic and adapted to cooperate with the eye to effect accommodating movement of the optic upon radial compression by a capsular bag of the eye, the movement assembly circumscribes the optic and comprises a member including a proximal end region coupled to the optic and a distal end region extending away from the optic and adapted to contact the capsular bag of the eye, the movement assembly is positioned relative to the optic so that, with the intraocular lens at rest, the optic vaults anteriorly of the distal end region of the movement assembly.
12. The intraocular lens of claim 11 wherein the optic has a far vision correction power for infinity in the unaccommodated state.
13. The intraocular lens of claim 11 wherein the distal end region of the movement assembly includes a peripheral edge configured to inhibit cell growth from the eye in front of or in back of the intraocular lens.
14. The intraocular lens of claim 11 sized to provide an amount of axial movement anteriorly in the eye in a range of about 0.5 mm to about 2.0 mm with about 1 mm of reduction in an equatorial diameter of the capsular bag.
15. The intraocular lens of claim 11 wherein the optic has a diameter in the range of about 3.5 mm to about 7 mm and the intraocular lens has an overall diameter in the range of about 8 mm to about 11 mm.
16. The intraocular lens of claim 11 wherein the movement assembly is adapted to be affixed to a capsular bag of the eye including the intraocular lens.
17. The intraocular lens of claim 11 wherein the movement assembly includes a hinge assembly positioned proximally of the distal end region.
18. The intraocular lens of claim 11 wherein the movement assembly has a minimum thickness at the proximal end region and a maximum thickness at the distal end region.
19. An intraocular lens comprising:
an optic adapted to focus light toward a retina of an eye; and
a movement assembly coupled to the optic and adapted to cooperate with the eye to effect accommodating movement of the optic, the movement assembly circumscribes the optic and comprises a member including a proximal end region coupled to the optic and a distal end region extending away from the optic and adapted to contact a capsular bag of the eye, the distal end region of the movement assembly includes a peripheral edge configured to inhibit cell growth from the eye in front of or in back of the intraocular lens.
20. The intraocular lens of claim 19 wherein the movement assembly has an anterior face and an opposing posterior face with a peripheral edge between the faces, the intersection of the peripheral edge and at least one of the anterior face and the posterior face forms a peripheral corner located at a discontinuity between the peripheral edge and the intersecting face.
21. The intraocular lens of claim 20 wherein cell growth from the eye in front of or in back of the intraocular lens is more inhibited relative to a substantially identical intraocular lens without the peripheral corner.
22. The intraocular lens of claim 19 wherein the optic has a far vision correction power for infinity in the unaccommodated state.
23. The intraocular lens of claim 19 sized to provide an amount of axial movement anteriorly in the eye in a range of about 0.5 mm to about 2.0 mm with about 1 mm of reduction in an equatorial diameter of the capsular bag.
24. The intraocular lens of claim 19 which is deformable for insertion through a small incision in the eye.
25. The intraocular lens of claim 19 wherein the movement assembly includes a hinge assembly positioned proximally of the distal end region.
26. A method for inserting an intraocular lens in an eye, the method comprising:
providing an intraocular lens of claim 1; and
placing the intraocular lens in the capsular bag of the eye so that the eye effectively cooperates with the intraocular lens to move the optic of the intraocular lens anteriorly in the eye to provide for positive focus accommodation.
27. The method of claim 26 wherein the placing step is effective so that the intraocular lens is radially compressed by the capsular bag of the eye to effect accommodating movement of the optic of the intraocular lens.
28. A method for inserting an intraocular lens in an eye, the method comprising:
providing an intraocular lens of claim 11; and
placing the intraocular lens in the capsular bag of the eye so that the eye effectively cooperates with the intraocular lens to move the optic of the intraocular lens anteriorly in the eye to provide for positive focus accommodation.
29. The method of claim 28 wherein the placing step is effective so that the intraocular lens is radially compressed by the capsular bag of the eye to effect accommodating movement of the optic of the intraocular lens.
30. A method for inserting an intraocular lens in an eye, the method comprising:
providing an intraocular lens of claim 19; and
placing the intraocular lens in the capsular bag of the eye so that the eye effectively cooperates with the intraocular lens to move the optic of the intraocular lens anteriorly in the eye to provide for positive focus accommodation.
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Cited By (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030204255A1 (en) * 2002-04-29 2003-10-30 Qun Peng Accommodative intraocular lens
US20040015236A1 (en) * 1991-11-18 2004-01-22 Sarfarazi Faezeh M. Sarfarazi elliptical accommodative intraocular lens for small incision surgery
US20060142855A1 (en) * 2004-12-29 2006-06-29 Jerome Vaudant Small incision intraocular lens with anti-PCO feature
US7662179B2 (en) 1999-04-09 2010-02-16 Sarfarazi Faezeh M Haptics for accommodative intraocular lens system
US7776088B2 (en) 2001-08-31 2010-08-17 Powervision, Inc. Intraocular lens system and method for power adjustment
US8034108B2 (en) * 2008-03-28 2011-10-11 Abbott Medical Optics Inc. Intraocular lens having a haptic that includes a cap
US8048155B2 (en) 2002-02-02 2011-11-01 Powervision, Inc. Intraocular implant devices
US8158712B2 (en) 2007-02-21 2012-04-17 Powervision, Inc. Polymeric materials suitable for ophthalmic devices and methods of manufacture
US8182531B2 (en) 2006-12-22 2012-05-22 Amo Groningen B.V. Accommodating intraocular lenses and associated systems, frames, and methods
US8303656B2 (en) 2003-03-06 2012-11-06 Powervision, Inc. Adaptive optic lens and method of making
US8314927B2 (en) 2007-07-23 2012-11-20 Powervision, Inc. Systems and methods for testing intraocular lenses
US8328869B2 (en) 2002-12-12 2012-12-11 Powervision, Inc. Accommodating intraocular lenses and methods of use
US8343216B2 (en) 2002-01-14 2013-01-01 Abbott Medical Optics Inc. Accommodating intraocular lens with outer support structure
US8361145B2 (en) 2002-12-12 2013-01-29 Powervision, Inc. Accommodating intraocular lens system having circumferential haptic support and method
US8425597B2 (en) 1999-04-30 2013-04-23 Abbott Medical Optics Inc. Accommodating intraocular lenses
US8447086B2 (en) 2009-08-31 2013-05-21 Powervision, Inc. Lens capsule size estimation
US8454688B2 (en) 2002-12-12 2013-06-04 Powervision, Inc. Accommodating intraocular lens having peripherally actuated deflectable surface and method
US8556967B2 (en) 1999-04-09 2013-10-15 Faezeh Mona Sarfarazi Interior bag for a capsular bag and injector
US8613766B2 (en) 2006-12-22 2013-12-24 Bausch-Lomb Incorporated Multi-element accommodative intraocular lens
US8668734B2 (en) 2010-07-09 2014-03-11 Powervision, Inc. Intraocular lens delivery devices and methods of use
US8900298B2 (en) 2010-02-23 2014-12-02 Powervision, Inc. Fluid for accommodating intraocular lenses
US8956408B2 (en) 2007-07-23 2015-02-17 Powervision, Inc. Lens delivery system
US8968396B2 (en) 2007-07-23 2015-03-03 Powervision, Inc. Intraocular lens delivery systems and methods of use
US9011532B2 (en) 2009-06-26 2015-04-21 Abbott Medical Optics Inc. Accommodating intraocular lenses
US9039760B2 (en) 2006-12-29 2015-05-26 Abbott Medical Optics Inc. Pre-stressed haptic for accommodating intraocular lens
US9198752B2 (en) 2003-12-15 2015-12-01 Abbott Medical Optics Inc. Intraocular lens implant having posterior bendable optic
US9271830B2 (en) 2002-12-05 2016-03-01 Abbott Medical Optics Inc. Accommodating intraocular lens and method of manufacture thereof
US9603703B2 (en) 2009-08-03 2017-03-28 Abbott Medical Optics Inc. Intraocular lens and methods for providing accommodative vision
US9610155B2 (en) 2008-07-23 2017-04-04 Powervision, Inc. Intraocular lens loading systems and methods of use
US9636213B2 (en) 2005-09-30 2017-05-02 Abbott Medical Optics Inc. Deformable intraocular lenses and lens systems
US9814570B2 (en) 1999-04-30 2017-11-14 Abbott Medical Optics Inc. Ophthalmic lens combinations
US9872763B2 (en) 2004-10-22 2018-01-23 Powervision, Inc. Accommodating intraocular lenses
US9987125B2 (en) 2012-05-02 2018-06-05 Johnson & Johnson Surgical Vision, Inc. Intraocular lens with shape changing capability to provide enhanced accomodation and visual acuity
US10045844B2 (en) 2002-02-02 2018-08-14 Powervision, Inc. Post-implant accommodating lens modification
US10195020B2 (en) 2013-03-15 2019-02-05 Powervision, Inc. Intraocular lens storage and loading devices and methods of use
US10299913B2 (en) 2009-01-09 2019-05-28 Powervision, Inc. Accommodating intraocular lenses and methods of use
US10390937B2 (en) 2007-07-23 2019-08-27 Powervision, Inc. Accommodating intraocular lenses
US10433949B2 (en) 2011-11-08 2019-10-08 Powervision, Inc. Accommodating intraocular lenses
US10835373B2 (en) 2002-12-12 2020-11-17 Alcon Inc. Accommodating intraocular lenses and methods of use
US11426270B2 (en) 2015-11-06 2022-08-30 Alcon Inc. Accommodating intraocular lenses and methods of manufacturing
US11471272B2 (en) 2019-10-04 2022-10-18 Alcon Inc. Adjustable intraocular lenses and methods of post-operatively adjusting intraocular lenses
US11707354B2 (en) 2017-09-11 2023-07-25 Amo Groningen B.V. Methods and apparatuses to increase intraocular lenses positional stability

Families Citing this family (84)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000052516A2 (en) 1999-03-01 2000-09-08 Boston Innovative Optics, Inc. System and method for increasing the depth of focus of the human eye
US20030078657A1 (en) 2001-01-25 2003-04-24 Gholam-Reza Zadno-Azizi Materials for use in accommodating intraocular lens system
US20060184244A1 (en) * 2005-02-14 2006-08-17 Nguyen Tuan A Biasing system for intraocular lens
US6786934B2 (en) 2001-01-25 2004-09-07 Visiogen, Inc. Biasing element for intraocular lens system
US20030078658A1 (en) 2001-01-25 2003-04-24 Gholam-Reza Zadno-Azizi Single-piece accomodating intraocular lens system
US8062361B2 (en) * 2001-01-25 2011-11-22 Visiogen, Inc. Accommodating intraocular lens system with aberration-enhanced performance
US7780729B2 (en) 2004-04-16 2010-08-24 Visiogen, Inc. Intraocular lens
US20120016349A1 (en) 2001-01-29 2012-01-19 Amo Development, Llc. Hybrid ophthalmic interface apparatus and method of interfacing a surgical laser with an eye
IL141529A0 (en) * 2001-02-20 2002-03-10 Ben Nun Yehoshua Intraocular lens with scleral fixation capability
IL145015A0 (en) * 2001-08-21 2002-06-30 Nun Yehoshua Ben Accommodating lens
WO2003059196A2 (en) 2002-01-14 2003-07-24 Advanced Medical Optics, Inc. Accommodating intraocular lens with elongated suspension structure
US7025783B2 (en) * 2002-01-14 2006-04-11 Advanced Medical Optics, Inc. Accommodating intraocular lens with integral capsular bag ring
US7261737B2 (en) * 2002-12-12 2007-08-28 Powervision, Inc. Accommodating intraocular lens system and method
US20030187504A1 (en) * 2002-04-01 2003-10-02 Weinschenk Joseph I. Adjustable intraocular lens
US7160324B2 (en) 2002-05-17 2007-01-09 Amo Groningen, B.V. Method in eye surgery
US7018409B2 (en) * 2002-09-13 2006-03-28 Advanced Medical Optics, Inc. Accommodating intraocular lens assembly with aspheric optic design
US20040082993A1 (en) 2002-10-25 2004-04-29 Randall Woods Capsular intraocular lens implant having a refractive liquid therein
CA2507694C (en) * 2002-12-12 2012-07-31 Victor Esch Accommodating intraocular lens system and method
US7247168B2 (en) * 2002-12-12 2007-07-24 Powervision, Inc. Accommodating intraocular lens system and method
US7637947B2 (en) * 2002-12-12 2009-12-29 Powervision, Inc. Accommodating intraocular lens system having spherical aberration compensation and method
EP1569581A4 (en) * 2002-12-12 2006-09-20 Powervision Lens system for power adjustment using micropumps
US7068336B2 (en) * 2002-12-13 2006-06-27 Lg.Philips Lcd Co., Ltd. Liquid crystal display device having variable viewing angle
US20040153150A1 (en) * 2003-01-30 2004-08-05 Advanced Medical Optics, Inc. Composite anterior chamber intraocular lens and method of manufacture thereof
DE10312551A1 (en) * 2003-03-21 2004-10-07 Müller, Klaus, Dr.med. Intraocular, accommodatively movable implant
US7628810B2 (en) 2003-05-28 2009-12-08 Acufocus, Inc. Mask configured to maintain nutrient transport without producing visible diffraction patterns
US6951391B2 (en) * 2003-06-16 2005-10-04 Apollo Optical Systems Llc Bifocal multiorder diffractive lenses for vision correction
US20050046794A1 (en) 2003-06-17 2005-03-03 Silvestrini Thomas A. Method and apparatus for aligning a mask with the visual axis of an eye
US6960231B2 (en) * 2003-07-14 2005-11-01 Alcon, Inc. Intraocular lens system
CA2540166A1 (en) * 2003-09-30 2005-04-14 Bausch & Lomb Incorporated Intraocular lens for inhibiting pco and aco
IL161706A0 (en) 2004-04-29 2004-09-27 Nulens Ltd Intraocular lens fixation device
US7156516B2 (en) * 2004-08-20 2007-01-02 Apollo Optical Systems Llc Diffractive lenses for vision correction
US7025456B2 (en) * 2004-08-20 2006-04-11 Apollo Optical Systems, Llc Diffractive lenses for vision correction
US7300464B2 (en) * 2004-09-30 2007-11-27 Alcon, Inc. Intraocular lens
US7815678B2 (en) * 2004-10-13 2010-10-19 Nulens Ltd. Accommodating intraocular lens (AIOL), and AIOL assemblies including same
US8377123B2 (en) * 2004-11-10 2013-02-19 Visiogen, Inc. Method of implanting an intraocular lens
WO2006054130A1 (en) * 2004-11-19 2006-05-26 Bausch & Lomb Incorporated Thin iol
US20080300680A1 (en) * 2005-03-30 2008-12-04 Nulens Ltd Accommodating Intraocular Lens (Aiol) and Discrete Components Therefor
US7976577B2 (en) 2005-04-14 2011-07-12 Acufocus, Inc. Corneal optic formed of degradation resistant polymer
US7591849B2 (en) 2005-07-01 2009-09-22 Bausch & Lomb Incorpoted Multi-component accommodative intraocular lens with compressible haptic
US20070010881A1 (en) * 2005-07-11 2007-01-11 Alcon, Inc. Intraocular lens system
US8038711B2 (en) 2005-07-19 2011-10-18 Clarke Gerald P Accommodating intraocular lens and methods of use
WO2007019389A1 (en) * 2005-08-05 2007-02-15 Visiogen, Inc. Accommodating diffractive intraocular lens
US20070168027A1 (en) * 2006-01-13 2007-07-19 Brady Daniel G Accommodating diffractive intraocular lens
US20070168028A1 (en) * 2006-01-18 2007-07-19 Alcon Manufacturing, Ltd. Posterior chamber phakic intraocular lens
WO2007134019A2 (en) * 2006-05-08 2007-11-22 Bausch & Lomb Incorporated Accommodative intraocular lens having defined axial compression characteristics
US20070260309A1 (en) * 2006-05-08 2007-11-08 Richardson Gary A Accommodating intraocular lens having a recessed anterior optic
US20090198247A1 (en) * 2006-08-25 2009-08-06 Nulens Ltd. Intraocular lens implantation kit
CA2674018C (en) 2006-12-29 2015-05-26 Advanced Medical Optics, Inc. Multifocal accommodating intraocular lens
US7713299B2 (en) 2006-12-29 2010-05-11 Abbott Medical Optics Inc. Haptic for accommodating intraocular lens
US8034106B2 (en) * 2007-02-02 2011-10-11 Adoptics Ag Interfacial refraction accommodating lens (IRAL)
US7857850B2 (en) * 2007-02-02 2010-12-28 Adoptics Ag Interfacial refraction accommodating lens (IRAL)
ATE483427T1 (en) * 2007-03-05 2010-10-15 Nulens Ltd UNIFORM ACCOMMODATION INTRAOCULAR LENSES (AIOLS) AND DISCRETE BASE ELEMENTS FOR USE THEREWITH
USD702346S1 (en) 2007-03-05 2014-04-08 Nulens Ltd. Haptic end plate for use in an intraocular assembly
ES2387702T3 (en) * 2007-05-29 2012-09-28 Steven J. Dell Accommodative intraocular lens that has a haptic plate
US20090228101A1 (en) * 2007-07-05 2009-09-10 Visiogen, Inc. Intraocular lens with post-implantation adjustment capabilities
US8414646B2 (en) 2007-12-27 2013-04-09 Forsight Labs, Llc Intraocular, accommodating lens and methods of use
US8167941B2 (en) 2008-01-03 2012-05-01 Forsight Labs, Llc Intraocular, accommodating lens and methods of use
US20090198326A1 (en) * 2008-01-31 2009-08-06 Medennium Inc. Accommodative intraocular lens system
ES2377456T3 (en) * 2008-07-24 2012-03-27 Nulens Ltd Accommodative intraocular lens capsules (IOLs)
US8222360B2 (en) * 2009-02-13 2012-07-17 Visiogen, Inc. Copolymers for intraocular lens systems
WO2010129905A1 (en) * 2009-05-08 2010-11-11 Innolene Llc Ocular lens
EP2464311B1 (en) 2009-08-13 2017-11-15 AcuFocus, Inc. Masked intraocular implants and lenses
USD656526S1 (en) 2009-11-10 2012-03-27 Acufocus, Inc. Ocular mask
US9220590B2 (en) 2010-06-10 2015-12-29 Z Lens, Llc Accommodative intraocular lens and method of improving accommodation
US9585745B2 (en) 2010-06-21 2017-03-07 James Stuart Cumming Foldable intraocular lens with rigid haptics
US10736732B2 (en) 2010-06-21 2020-08-11 James Stuart Cumming Intraocular lens with longitudinally rigid plate haptic
US9295544B2 (en) 2012-06-05 2016-03-29 James Stuart Cumming Intraocular lens
US8734512B2 (en) 2011-05-17 2014-05-27 James Stuart Cumming Biased accommodating intraocular lens
US9918830B2 (en) 2010-06-21 2018-03-20 James Stuart Cumming Foldable intraocular lens with rigid haptics
US8523942B2 (en) 2011-05-17 2013-09-03 James Stuart Cumming Variable focus intraocular lens
US9351825B2 (en) 2013-12-30 2016-05-31 James Stuart Cumming Semi-flexible posteriorly vaulted acrylic intraocular lens for the treatment of presbyopia
US9295545B2 (en) 2012-06-05 2016-03-29 James Stuart Cumming Intraocular lens
US9295546B2 (en) 2013-09-24 2016-03-29 James Stuart Cumming Anterior capsule deflector ridge
WO2013082545A1 (en) 2011-12-02 2013-06-06 Acufocus, Inc. Ocular mask having selective spectral transmission
US9364318B2 (en) 2012-05-10 2016-06-14 Z Lens, Llc Accommodative-disaccommodative intraocular lens
US9204962B2 (en) 2013-03-13 2015-12-08 Acufocus, Inc. In situ adjustable optical mask
US9427922B2 (en) 2013-03-14 2016-08-30 Acufocus, Inc. Process for manufacturing an intraocular lens with an embedded mask
US9615916B2 (en) 2013-12-30 2017-04-11 James Stuart Cumming Intraocular lens
IL245775A0 (en) 2016-05-22 2016-08-31 Joshua Ben Nun Hybrid accommodating intraocular lens
JP7074960B2 (en) 2016-08-24 2022-05-25 カール ツァイス メディテック アーゲー Dual Mode Adjustable-Non-Adjustable Intraocular Lens
US10663763B2 (en) 2017-07-12 2020-05-26 Vision Pro (Wuxi) Ltd Multifocal intraocular lens
US10881505B2 (en) * 2017-12-21 2021-01-05 Cad Zeiss Meditec Production, LLC Ophthalmosurgical injector system
EP3821851A4 (en) * 2018-07-13 2022-01-26 Eyebright Medical Technology (Beijing) Co., Ltd. Intraocular lens and manufacturing method therefor
GB2578639A (en) 2018-11-02 2020-05-20 Rayner Intraocular Lenses Ltd Hybrid accommodating intraocular lens assemblages including discrete lens unit with segmented lens haptics

Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2405989A (en) * 1941-08-12 1946-08-20 Beach Lens Corp Lens
US3922728A (en) * 1974-08-15 1975-12-02 Krasnov Mikhail M Artificial crystalline lens
US4162122A (en) * 1977-09-14 1979-07-24 Cohen Allen L Zonal bifocal contact lens
US4315673A (en) * 1978-04-06 1982-02-16 Optische Werke G. Rodenstock Progressive power ophthalmic lens
US4404694A (en) * 1982-03-18 1983-09-20 Kelman Charles D Intraocular lens
US4476591A (en) * 1982-10-07 1984-10-16 Arnott Eric J Lens implants for insertion in the human eye
US4990159A (en) * 1988-12-02 1991-02-05 Kraff Manus C Intraocular lens apparatus with haptics of varying cross-sectional areas
US5192318A (en) * 1986-06-05 1993-03-09 Schneider Richard T One-piece bifocal intraocular lens construction
US5702440A (en) * 1996-01-26 1997-12-30 Allergan Multifocal ophthalmic lens for dim-lighting conditions
US5766244A (en) * 1991-05-23 1998-06-16 Binder; Helmut Intraocular artificial lens and method for fabricating same
US6217612B1 (en) * 1999-09-10 2001-04-17 Randall Woods Intraocular lens implant having eye accommodating capabilities
US6228115B1 (en) * 1998-11-05 2001-05-08 Bausch & Lomb Surgical, Inc. Intraocular lenses with improved axial stability

Family Cites Families (139)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE25286E (en) 1962-11-13 Bifocal corneal contact lens
US1483509A (en) 1921-05-05 1924-02-12 Franklin Optical Company Process of making fused bifocal lenses
US2129305A (en) 1936-08-21 1938-09-06 Feinbloom William Contact lens
US2274142A (en) 1940-01-15 1942-02-24 Revalens Co Multifocal ophthalmic lens
US2511517A (en) 1947-01-31 1950-06-13 Bell & Howell Co Method of producing optical glass of varied refractive index
US3031927A (en) 1958-03-03 1962-05-01 Plastic Contact Lens Company Bifocal corneal contact lens
US3034403A (en) 1959-04-03 1962-05-15 Neefe Hamilton Res Company Contact lens of apparent variable light absorption
US3227507A (en) 1961-08-16 1966-01-04 Feinbloom William Corneal contact lens having inner ellipsoidal surface
US3339997A (en) 1962-07-30 1967-09-05 Plastic Contact Lens Company Bifocal ophthalmic lens having different color distance and near vision zones
US3210894A (en) 1962-08-13 1965-10-12 Kollmorgen Corp Method of producing aspheric surfaces on mirrors or lenses
US3420006A (en) 1964-01-27 1969-01-07 Howard J Barnett Apparatus for grinding multifocal lens
US3431327A (en) 1964-08-31 1969-03-04 George F Tsuetaki Method of making a bifocal contact lens with an embedded metal weight
US3482906A (en) 1965-10-04 1969-12-09 David Volk Aspheric corneal contact lens series
US3542461A (en) 1967-11-20 1970-11-24 Du Pont Contact lens having an index of refraction approximating that of human tears
FR2097216A5 (en) 1970-05-27 1972-03-03 Anvar
US4055378A (en) 1971-12-31 1977-10-25 Agfa-Gevaert Aktiengesellschaft Silicone contact lens with hydrophilic surface treatment
CA1012392A (en) 1973-08-16 1977-06-21 American Optical Corporation Progressive power ophthalmic lens
US3932148A (en) 1975-01-21 1976-01-13 Criterion Manufacturing Company, Inc. Method and apparatus for making complex aspheric optical surfaces
DE2610203B2 (en) 1976-03-11 1981-01-22 Optische Werke G. Rodenstock, 8000 Muenchen Progressive lens
DE2702117A1 (en) 1977-01-20 1978-07-27 Soehnges Optik Loose-seat contact lens - has surface structures on securing surface against corneal surface formed by moulding
US4210391A (en) 1977-09-14 1980-07-01 Cohen Allen L Multifocal zone plate
US4195919A (en) 1977-10-31 1980-04-01 Shelton William A Contact lens with reduced spherical aberration for aphakic eyes
US4199231A (en) 1978-08-21 1980-04-22 Evans Carl H Hydrogel contact lens
US4253199A (en) 1978-09-25 1981-03-03 Surgical Design Corporation Surgical method and apparatus for implants for the eye
US4340283A (en) 1978-12-18 1982-07-20 Cohen Allen L Phase shift multifocal zone plate
US4338005A (en) 1978-12-18 1982-07-06 Cohen Allen L Multifocal phase place
US4254509A (en) 1979-04-09 1981-03-10 Tennant Jerald L Accommodating intraocular implant
US4274717A (en) 1979-05-18 1981-06-23 Younger Manufacturing Company Ophthalmic progressive power lens and method of making same
JPS5942286B2 (en) 1979-08-24 1984-10-13 セイコーエプソン株式会社 eyeglass lenses
US4316293A (en) 1979-08-27 1982-02-23 Bayers Jon Herbert Flexible intraocular lens
US4418991A (en) 1979-09-24 1983-12-06 Breger Joseph L Presbyopic contact lens
US4307945A (en) 1980-02-14 1981-12-29 Itek Corporation Progressively varying focal power opthalmic lens
US4377329A (en) 1980-02-26 1983-03-22 Stanley Poler Contact lens or the like
USRE32525F1 (en) 1980-04-01 1989-05-09 Universal intraocular lens and a method of measuring an eye chamber size
US4370760A (en) 1981-03-25 1983-02-01 Kelman Charles D Anterior chamber intraocular lens
US4402579A (en) 1981-07-29 1983-09-06 Lynell Medical Technology Inc. Contact-lens construction
US4409691A (en) 1981-11-02 1983-10-18 Levy Chauncey F Focussable intraocular lens
US5776191A (en) 1982-02-05 1998-07-07 Staar Surgical Company Fixation system for intraocular lens structures
US4702244A (en) 1982-02-05 1987-10-27 Staar Surgical Company Surgical device for implantation of a deformable intraocular lens
DE3222099C2 (en) 1982-06-11 1984-06-20 Titmus Eurocon Kontaktlinsen Gmbh & Co Kg, 8750 Aschaffenburg Bifocal contact lens of the bivisual type
GB2124500B (en) 1982-07-22 1986-04-30 Mazzocco Thomas R Improved fixation system for intraocularers structures
US4504982A (en) 1982-08-05 1985-03-19 Optical Radiation Corporation Aspheric intraocular lens
US4573775A (en) 1982-08-19 1986-03-04 Vistakon, Inc. Bifocal contact lens
US4888015A (en) 1982-08-20 1989-12-19 Domino Rudolph S Method of replacing an eye lens
EP0104832B1 (en) 1982-09-29 1987-11-11 Pilkington Brothers P.L.C. Improvements in or relating to ophthalmic lenses
US4890913A (en) 1982-10-13 1990-01-02 Carle John T De Zoned multi-focal contact lens
DE3381691D1 (en) 1982-10-13 1990-08-02 Ng Trustees & Nominees Ltd BIFOCAL CONTACT LENSES.
GB2129157B (en) 1982-10-27 1986-02-05 Pilkington Perkin Elmer Ltd Bifocal contact lenses having defractive power
DE3246306A1 (en) 1982-12-14 1984-06-14 Titmus Eurocon Kontaktlinsen Gmbh & Co Kg, 8750 Aschaffenburg Bifocal lens of bivisual type
US4580882A (en) 1983-04-21 1986-04-08 Benjamin Nuchman Continuously variable contact lens
US4618229A (en) 1983-07-22 1986-10-21 Bausch & Lomb Incorporated Bifocal contact lens
US4551864A (en) 1983-08-18 1985-11-12 Iolab Corporation Anterior chamber lens
DE3332313A1 (en) 1983-09-07 1985-04-04 Titmus Eurocon Kontaktlinsen GmbH, 8750 Aschaffenburg MULTIFOCAL, ESPECIALLY BIFOCAL, INTRAOCULAR ARTIFICIAL EYE LENS
GB2146791B (en) 1983-09-16 1987-01-28 Suwa Seikosha Kk Progressive multifocal ophthalmic lens
US4636049A (en) 1983-09-20 1987-01-13 University Optical Products Co. Concentric bifocal contact lens
US4560383A (en) 1983-10-27 1985-12-24 Leiske Larry G Anterior chamber intraocular lens
US4687484A (en) 1983-12-12 1987-08-18 Kaplan Linda J Anterior chamber intraocular lens
US4596578A (en) 1984-01-30 1986-06-24 Kelman Charles D Intraocular lens with miniature optic
US4636211A (en) 1984-03-13 1987-01-13 Nielsen J Mchenry Bifocal intra-ocular lens
US4720286A (en) 1984-07-20 1988-01-19 Bailey Kelvin E Multifocus intraocular lens
US4976732A (en) 1984-09-12 1990-12-11 International Financial Associates Holdings, Inc. Optical lens for the human eye
US4725278A (en) 1985-01-22 1988-02-16 Shearing Steven P Intraocular lens
US4759762A (en) 1985-03-08 1988-07-26 Grendahl Dennis T Accommodating lens
US4693572A (en) 1985-06-03 1987-09-15 Fused Kontacts Of Chicago, Inc. Monocentric bifocal corneal contact lens
US4752123A (en) 1985-11-19 1988-06-21 University Optical Products Co. Concentric bifocal contact lens with two distance power regions
US4890912A (en) 1986-01-24 1990-01-02 Rients Visser Trifocal eye-contact lens
GB2192291B (en) 1986-03-04 1990-08-22 Gupta Anil K Progressive power contact lens.
US4725277A (en) 1986-05-14 1988-02-16 Precision-Cosmet Co., Inc. Intraocular lens with tapered haptics
EP0248489A3 (en) 1986-06-02 1989-09-06 Gregory N. Miller Contact lens and method of making same
US4676792A (en) 1986-08-26 1987-06-30 Donald Praeger Method and artificial intraocular lens device for the phakic treatment of myopia
US4842601A (en) 1987-05-18 1989-06-27 Smith S Gregory Accommodating intraocular lens and method of implanting and using same
US5201762A (en) 1987-05-20 1993-04-13 Hauber Frederick A Intraocular archromatic lens
US4790847A (en) 1987-05-26 1988-12-13 Woods Randall L Intraocular lens implant having eye focusing capabilities
US5166711A (en) 1987-06-01 1992-11-24 Valdemar Portney Multifocal ophthalmic lens
US5166712A (en) 1987-06-01 1992-11-24 Valdemar Portney Multifocal ophthalmic lens
US5225858A (en) 1987-06-01 1993-07-06 Valdemar Portney Multifocal ophthalmic lens
US5270744A (en) 1987-06-01 1993-12-14 Valdemar Portney Multifocal ophthalmic lens
US5019099A (en) 1987-07-02 1991-05-28 Nordan Lee T Intraocular multifocal lens method for correcting the aphakic eye
US4769033A (en) 1987-07-02 1988-09-06 Nordan Lee T Intraocular multifocal lens
US4917681A (en) 1987-08-24 1990-04-17 Nordan Lee T Intraocular multifocal lens
US4932968A (en) 1987-07-07 1990-06-12 Caldwell Delmar R Intraocular prostheses
US4906246A (en) 1987-08-24 1990-03-06 Grendahl Dennis T Cylindrically segmented zone of focus artificial hydrogel lens
US4921496A (en) 1987-08-24 1990-05-01 Grendahl Dennis T Radially segemented zone of focus artificial hydrogel lens
US4919663A (en) 1987-08-24 1990-04-24 Grendahl Dennis T Laminated zone of focus artificial hydrogel lens
US5158572A (en) 1987-09-10 1992-10-27 Nielsen James Mchenry Multifocal intraocular lens
US5047052A (en) 1987-11-06 1991-09-10 Seymour Dubroff Anterior chamber intraocular lens with four point fixation
US4881804A (en) 1987-11-12 1989-11-21 Cohen Allen L Multifocal phase plate with a pure refractive portion
US4888012A (en) 1988-01-14 1989-12-19 Gerald Horn Intraocular lens assemblies
GB2215076A (en) 1988-02-02 1989-09-13 Dennis T Grendahl Intraocular lens having a hard optic and a soft skirt
IT1215851B (en) 1988-02-11 1990-02-22 Renato Liffredo INTRAOCULAR LENS WITH CHROMATIC CORRECTION AND ABSORPTION DIAGRAM.
US5000559A (en) 1988-02-29 1991-03-19 Nikon Corporation Ophthalmic lenses having progressively variable refracting power
CA1316728C (en) 1988-04-01 1993-04-27 Michael J. Simpson Multi-focal diffractive ophthalmic lenses
US5089024A (en) 1988-04-19 1992-02-18 Storz Instrument Company Multi-focal intraocular lens
FR2631228B1 (en) 1988-05-11 1990-08-10 Domilens Laboratoires INTRA-EYE IMPLANT OF PREVIOUS CHAMBER
US4932970A (en) 1988-05-17 1990-06-12 Allergan, Inc. Ophthalmic lens
US4898416A (en) 1988-07-05 1990-02-06 Hughes Aircraft Company Pickup device
US4923296A (en) 1988-07-14 1990-05-08 Erickson Paul M Oriented simultaneous vision bifocal contact lenses or the like utilizing introaocular suppression of blur
CN1020134C (en) 1988-07-20 1993-03-17 艾伦·L·科恩 Multifocal optical device
US5192317A (en) 1988-07-26 1993-03-09 Irvin Kalb Multi focal intra-ocular lens
US4830481A (en) 1988-08-12 1989-05-16 Minnesota Mining And Manufacturing Company Multifocal diffractive lens
US4932966A (en) 1988-08-15 1990-06-12 Storz Instrument Company Accommodating intraocular lens
US4994082A (en) 1988-09-09 1991-02-19 Ophthalmic Ventures Limited Partnership Accommodating intraocular lens
US4892543A (en) 1989-02-02 1990-01-09 Turley Dana F Intraocular lens providing accomodation
FR2642854B1 (en) 1989-02-03 1991-05-03 Essilor Int OPTICAL LENS WITH SIMULTANEOUS VISION FOR PRESBYTIA CORRECTION
FR2647227B1 (en) 1989-05-19 1991-08-23 Essilor Int OPTICAL COMPONENT, SUCH AS AN INTRAOCULAR IMPLANT OR CONTACT LENS, SUITABLE FOR CORRECTING THE VISION OF AN INDIVIDUAL
US4955902A (en) 1989-11-13 1990-09-11 Kelman Charles D Decentered intraocular lens
US5002382A (en) 1989-12-07 1991-03-26 Leonard Seidner Multifocal corneal contact lenses
US5476514A (en) 1990-04-27 1995-12-19 Cumming; J. Stuart Accommodating intraocular lens
US5096285A (en) 1990-05-14 1992-03-17 Iolab Corporation Multifocal multizone diffractive ophthalmic lenses
US5147397A (en) 1990-07-03 1992-09-15 Allergan, Inc. Intraocular lens and method for making same
US5171266A (en) 1990-09-04 1992-12-15 Wiley Robert G Variable power intraocular lens with astigmatism correction
US5173723A (en) 1990-10-02 1992-12-22 Volk Donald A Aspheric ophthalmic accommodating lens design for intraocular lens and contact lens
US5112351A (en) 1990-10-12 1992-05-12 Ioptex Research Inc. Multifocal intraocular lenses
US5260727A (en) 1990-10-22 1993-11-09 Oksman Henry C Wide depth of focus intraocular and contact lenses
US5258025A (en) 1990-11-21 1993-11-02 Fedorov Svjatoslav N Corrective intraocular lens
US5326347A (en) 1991-08-12 1994-07-05 Cumming J Stuart Intraocular implants
EP0601055B1 (en) 1991-08-16 2000-06-07 GALIN, Miles A. Medicament coated refractive anterior chamber ocular implant
US5578081A (en) 1991-11-12 1996-11-26 Henry H. McDonald Eye muscle responsive artificial lens unit
US5275623A (en) 1991-11-18 1994-01-04 Faezeh Sarfarazi Elliptical accommodative intraocular lens for small incision surgery
NL9200400A (en) 1992-03-04 1993-10-01 Jose Jorge Pavlotzky Handelend BIFOCAL CONTACT LENS, AND METHOD FOR MANUFACTURING SUCH CONTACT LENSES
US5443506A (en) 1992-11-18 1995-08-22 Garabet; Antoine L. Lens with variable optical properties
US5354335A (en) 1993-02-04 1994-10-11 Isaac Lipshitz Intraocular insert for implantation in the human eye
RU2033114C1 (en) 1993-04-22 1995-04-20 Межотраслевой научно-технический комплекс "Микрохирургия глаза" Artificial crystalline lens
US5489302A (en) 1994-05-24 1996-02-06 Skottun; Bernt C. Accommodating intraocular lens
JP3745394B2 (en) 1994-07-04 2006-02-15 武敏 鈴木 Intraocular lens
US6013101A (en) * 1994-11-21 2000-01-11 Acuity (Israel) Limited Accommodating intraocular lens implant
US5549760A (en) 1994-12-01 1996-08-27 White Consolidated Industries, Inc. Mounting device for dishwasher insulation
US5628795A (en) 1995-03-15 1997-05-13 Langerman David W Spare parts for use in ophthalmic surgical procedures
US5682223A (en) 1995-05-04 1997-10-28 Johnson & Johnson Vision Products, Inc. Multifocal lens designs with intermediate optical powers
HUP9601126A3 (en) * 1995-05-04 1999-10-28 Johnson & Johnson Vision Prod Concentric, aspheric, multifocal lens
US5652638A (en) 1995-05-04 1997-07-29 Johnson & Johnson Vision Products, Inc. Concentric annular ring lens designs for astigmatism
US5684560A (en) 1995-05-04 1997-11-04 Johnson & Johnson Vision Products, Inc. Concentric ring single vision lens designs
US5607472A (en) 1995-05-09 1997-03-04 Emory University Intraocular lens for restoring accommodation and allows adjustment of optical power
US5769890B1 (en) 1997-01-16 2000-09-05 Surgical Concepts Inc Placement of second artificial lens in eye to correct for optical defects of first artificial lens in eye
US5928283A (en) 1997-06-26 1999-07-27 Visioncare Ltd Telescopic device for an intraocular lens
US5843188A (en) 1997-10-20 1998-12-01 Henry H. McDonald Accommodative lens implantation
US5876442A (en) 1998-01-15 1999-03-02 Visioncare Ltd. Intraocular lens implant with telescope support
US5814103A (en) 1998-01-15 1998-09-29 Visioncare Ltd. Intraocular lens and telescope with mating fasteners
US6176878B1 (en) * 1998-12-17 2001-01-23 Allergan Sales, Inc. Accommodating intraocular lens

Patent Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2405989A (en) * 1941-08-12 1946-08-20 Beach Lens Corp Lens
US3922728A (en) * 1974-08-15 1975-12-02 Krasnov Mikhail M Artificial crystalline lens
US4162122A (en) * 1977-09-14 1979-07-24 Cohen Allen L Zonal bifocal contact lens
US4315673A (en) * 1978-04-06 1982-02-16 Optische Werke G. Rodenstock Progressive power ophthalmic lens
US4404694A (en) * 1982-03-18 1983-09-20 Kelman Charles D Intraocular lens
US4476591A (en) * 1982-10-07 1984-10-16 Arnott Eric J Lens implants for insertion in the human eye
US5192318A (en) * 1986-06-05 1993-03-09 Schneider Richard T One-piece bifocal intraocular lens construction
US4990159A (en) * 1988-12-02 1991-02-05 Kraff Manus C Intraocular lens apparatus with haptics of varying cross-sectional areas
US5766244A (en) * 1991-05-23 1998-06-16 Binder; Helmut Intraocular artificial lens and method for fabricating same
US5702440A (en) * 1996-01-26 1997-12-30 Allergan Multifocal ophthalmic lens for dim-lighting conditions
US6228115B1 (en) * 1998-11-05 2001-05-08 Bausch & Lomb Surgical, Inc. Intraocular lenses with improved axial stability
US6217612B1 (en) * 1999-09-10 2001-04-17 Randall Woods Intraocular lens implant having eye accommodating capabilities

Cited By (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040015236A1 (en) * 1991-11-18 2004-01-22 Sarfarazi Faezeh M. Sarfarazi elliptical accommodative intraocular lens for small incision surgery
US9149356B2 (en) 1999-04-09 2015-10-06 Faezeh Mona Sarfarazi Interior bag for a capsular bag and injector
US8556967B2 (en) 1999-04-09 2013-10-15 Faezeh Mona Sarfarazi Interior bag for a capsular bag and injector
US7662179B2 (en) 1999-04-09 2010-02-16 Sarfarazi Faezeh M Haptics for accommodative intraocular lens system
US9814570B2 (en) 1999-04-30 2017-11-14 Abbott Medical Optics Inc. Ophthalmic lens combinations
US8425597B2 (en) 1999-04-30 2013-04-23 Abbott Medical Optics Inc. Accommodating intraocular lenses
US7776088B2 (en) 2001-08-31 2010-08-17 Powervision, Inc. Intraocular lens system and method for power adjustment
US8992609B2 (en) 2001-08-31 2015-03-31 Powervision, Inc. Intraocular lens system and method for power adjustment
US9504560B2 (en) 2002-01-14 2016-11-29 Abbott Medical Optics Inc. Accommodating intraocular lens with outer support structure
US8343216B2 (en) 2002-01-14 2013-01-01 Abbott Medical Optics Inc. Accommodating intraocular lens with outer support structure
US8048155B2 (en) 2002-02-02 2011-11-01 Powervision, Inc. Intraocular implant devices
US9456895B2 (en) 2002-02-02 2016-10-04 Powervision, Inc. Accommodating intraocular lens
US10045844B2 (en) 2002-02-02 2018-08-14 Powervision, Inc. Post-implant accommodating lens modification
US8425599B2 (en) 2002-02-02 2013-04-23 Powervision, Inc. Accommodating intraocular lenses and methods of use
US10433950B2 (en) 2002-02-02 2019-10-08 Powervision, Inc. Accommodating intraocular lenses
US6926736B2 (en) * 2002-04-29 2005-08-09 Alcon, Inc. Accommodative intraocular lens
US20030204255A1 (en) * 2002-04-29 2003-10-30 Qun Peng Accommodative intraocular lens
US9271830B2 (en) 2002-12-05 2016-03-01 Abbott Medical Optics Inc. Accommodating intraocular lens and method of manufacture thereof
US10206773B2 (en) 2002-12-05 2019-02-19 Johnson & Johnson Surgical Vision, Inc. Accommodating intraocular lens and method of manufacture thereof
US9872762B2 (en) 2002-12-12 2018-01-23 Powervision, Inc. Accommodating intraocular lenses
US9277987B2 (en) 2002-12-12 2016-03-08 Powervision, Inc. Accommodating intraocular lenses
US9855137B2 (en) 2002-12-12 2018-01-02 Powervision, Inc. Accommodating intraocular lenses and methods of use
US11751991B2 (en) 2002-12-12 2023-09-12 Alcon Inc. Accommodating intraocular lenses and methods of use
US8454688B2 (en) 2002-12-12 2013-06-04 Powervision, Inc. Accommodating intraocular lens having peripherally actuated deflectable surface and method
US9795473B2 (en) 2002-12-12 2017-10-24 Powervision, Inc. Accommodating intraocular lenses
US10835373B2 (en) 2002-12-12 2020-11-17 Alcon Inc. Accommodating intraocular lenses and methods of use
US8361145B2 (en) 2002-12-12 2013-01-29 Powervision, Inc. Accommodating intraocular lens system having circumferential haptic support and method
US8328869B2 (en) 2002-12-12 2012-12-11 Powervision, Inc. Accommodating intraocular lenses and methods of use
US8303656B2 (en) 2003-03-06 2012-11-06 Powervision, Inc. Adaptive optic lens and method of making
US10534113B2 (en) 2003-03-06 2020-01-14 Powervision, Inc. Adaptive optic lens and method of making
US9198752B2 (en) 2003-12-15 2015-12-01 Abbott Medical Optics Inc. Intraocular lens implant having posterior bendable optic
US9872763B2 (en) 2004-10-22 2018-01-23 Powervision, Inc. Accommodating intraocular lenses
US7931686B2 (en) 2004-12-29 2011-04-26 Bausch & Lomb Incorporated Small incision intraocular lens with anti-PCO feature
US20060142855A1 (en) * 2004-12-29 2006-06-29 Jerome Vaudant Small incision intraocular lens with anti-PCO feature
US7569073B2 (en) 2004-12-29 2009-08-04 Bausch & Lomb Incorporated Small incision intraocular lens with anti-PCO feature
US9636213B2 (en) 2005-09-30 2017-05-02 Abbott Medical Optics Inc. Deformable intraocular lenses and lens systems
US10368979B2 (en) 2006-12-19 2019-08-06 Powervision, Inc. Accommodating intraocular lenses
US8496701B2 (en) 2006-12-22 2013-07-30 Amo Groningen B.V. Accommodating intraocular lenses and associated systems, frames, and methods
US8182531B2 (en) 2006-12-22 2012-05-22 Amo Groningen B.V. Accommodating intraocular lenses and associated systems, frames, and methods
US8613766B2 (en) 2006-12-22 2013-12-24 Bausch-Lomb Incorporated Multi-element accommodative intraocular lens
US9039760B2 (en) 2006-12-29 2015-05-26 Abbott Medical Optics Inc. Pre-stressed haptic for accommodating intraocular lens
US8158712B2 (en) 2007-02-21 2012-04-17 Powervision, Inc. Polymeric materials suitable for ophthalmic devices and methods of manufacture
US10350060B2 (en) 2007-07-23 2019-07-16 Powervision, Inc. Lens delivery system
US8968396B2 (en) 2007-07-23 2015-03-03 Powervision, Inc. Intraocular lens delivery systems and methods of use
US9855139B2 (en) 2007-07-23 2018-01-02 Powervision, Inc. Intraocular lens delivery systems and methods of use
US11759313B2 (en) 2007-07-23 2023-09-19 Alcon Inc. Lens delivery system
US8314927B2 (en) 2007-07-23 2012-11-20 Powervision, Inc. Systems and methods for testing intraocular lenses
US10390937B2 (en) 2007-07-23 2019-08-27 Powervision, Inc. Accommodating intraocular lenses
US8956408B2 (en) 2007-07-23 2015-02-17 Powervision, Inc. Lens delivery system
US8034108B2 (en) * 2008-03-28 2011-10-11 Abbott Medical Optics Inc. Intraocular lens having a haptic that includes a cap
US9968441B2 (en) 2008-03-28 2018-05-15 Johnson & Johnson Surgical Vision, Inc. Intraocular lens having a haptic that includes a cap
US9610155B2 (en) 2008-07-23 2017-04-04 Powervision, Inc. Intraocular lens loading systems and methods of use
US11166808B2 (en) 2009-01-09 2021-11-09 Alcon Inc. Accommodating intraocular lenses and methods of use
US10299913B2 (en) 2009-01-09 2019-05-28 Powervision, Inc. Accommodating intraocular lenses and methods of use
US10357356B2 (en) 2009-01-09 2019-07-23 Powervision, Inc. Accommodating intraocular lenses and methods of use
US10052194B2 (en) 2009-06-26 2018-08-21 Johnson & Johnson Surgical Vision, Inc. Accommodating intraocular lenses
US9011532B2 (en) 2009-06-26 2015-04-21 Abbott Medical Optics Inc. Accommodating intraocular lenses
US10105215B2 (en) 2009-08-03 2018-10-23 Johnson & Johnson Surgical Vision, Inc. Intraocular lens and methods for providing accommodative vision
US9603703B2 (en) 2009-08-03 2017-03-28 Abbott Medical Optics Inc. Intraocular lens and methods for providing accommodative vision
US8447086B2 (en) 2009-08-31 2013-05-21 Powervision, Inc. Lens capsule size estimation
US10980629B2 (en) 2010-02-23 2021-04-20 Alcon Inc. Fluid for accommodating intraocular lenses
US11737862B2 (en) 2010-02-23 2023-08-29 Alcon Inc. Fluid for accommodating intraocular lenses
US8900298B2 (en) 2010-02-23 2014-12-02 Powervision, Inc. Fluid for accommodating intraocular lenses
US10595989B2 (en) 2010-07-09 2020-03-24 Powervision, Inc. Intraocular lens delivery devices and methods of use
US8668734B2 (en) 2010-07-09 2014-03-11 Powervision, Inc. Intraocular lens delivery devices and methods of use
US11779456B2 (en) 2010-07-09 2023-10-10 Alcon Inc. Intraocular lens delivery devices and methods of use
US9693858B2 (en) 2010-07-09 2017-07-04 Powervision, Inc. Intraocular lens delivery devices and methods of use
US9044317B2 (en) 2010-07-09 2015-06-02 Powervision, Inc. Intraocular lens delivery devices and methods of use
US10433949B2 (en) 2011-11-08 2019-10-08 Powervision, Inc. Accommodating intraocular lenses
US11484402B2 (en) 2011-11-08 2022-11-01 Alcon Inc. Accommodating intraocular lenses
US9987125B2 (en) 2012-05-02 2018-06-05 Johnson & Johnson Surgical Vision, Inc. Intraocular lens with shape changing capability to provide enhanced accomodation and visual acuity
US10195020B2 (en) 2013-03-15 2019-02-05 Powervision, Inc. Intraocular lens storage and loading devices and methods of use
US11071622B2 (en) 2013-03-15 2021-07-27 Alcon Inc. Intraocular lens storage and loading devices and methods of use
US11793627B2 (en) 2013-03-15 2023-10-24 Alcon Inc. Intraocular lens storage and loading devices and methods of use
US11426270B2 (en) 2015-11-06 2022-08-30 Alcon Inc. Accommodating intraocular lenses and methods of manufacturing
US11707354B2 (en) 2017-09-11 2023-07-25 Amo Groningen B.V. Methods and apparatuses to increase intraocular lenses positional stability
US11660182B2 (en) 2019-10-04 2023-05-30 Alcon Inc. Adjustable intraocular lenses and methods of post-operatively adjusting intraocular lenses
US11471272B2 (en) 2019-10-04 2022-10-18 Alcon Inc. Adjustable intraocular lenses and methods of post-operatively adjusting intraocular lenses

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