DE60327326D1 - Partikel zur embolisation - Google Patents

Partikel zur embolisation

Info

Publication number
DE60327326D1
DE60327326D1 DE60327326T DE60327326T DE60327326D1 DE 60327326 D1 DE60327326 D1 DE 60327326D1 DE 60327326 T DE60327326 T DE 60327326T DE 60327326 T DE60327326 T DE 60327326T DE 60327326 D1 DE60327326 D1 DE 60327326D1
Authority
DE
Germany
Prior art keywords
embolization
particle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60327326T
Other languages
English (en)
Inventor
Robert F Rioux
Thomas V Casey
Janel Lanphere
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boston Scientific Ltd Barbados
Original Assignee
Boston Scientific Ltd Barbados
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boston Scientific Ltd Barbados filed Critical Boston Scientific Ltd Barbados
Application granted granted Critical
Publication of DE60327326D1 publication Critical patent/DE60327326D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/02Surgical adhesives or cements; Adhesives for colostomy devices containing inorganic materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/04X-ray contrast preparations
    • A61K49/0433X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0447Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
    • A61K49/0452Solutions, e.g. for injection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1241Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins
    • A61K51/1244Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins microparticles or nanoparticles, e.g. polymeric nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1635Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001Use of materials characterised by their function or physical properties
    • A61L24/0015Medicaments; Biocides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001Use of materials characterised by their function or physical properties
    • A61L24/0036Porous materials, e.g. foams or sponges
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/0047Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L24/0073Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix
    • A61L24/0089Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix containing inorganic fillers not covered by groups A61L24/0078 or A61L24/0084
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/102Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/418Agents promoting blood coagulation, blood-clotting agents, embolising agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606Coatings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/04Materials for stopping bleeding
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/36Materials or treatment for tissue regeneration for embolization or occlusion, e.g. vaso-occlusive compositions or devices
DE60327326T 2002-08-30 2003-08-29 Partikel zur embolisation Expired - Lifetime DE60327326D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/232,265 US7462366B2 (en) 2002-03-29 2002-08-30 Drug delivery particle
PCT/US2003/027358 WO2004020011A1 (en) 2002-08-30 2003-08-29 Embolization

Publications (1)

Publication Number Publication Date
DE60327326D1 true DE60327326D1 (de) 2009-06-04

Family

ID=31976966

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60327326T Expired - Lifetime DE60327326D1 (de) 2002-08-30 2003-08-29 Partikel zur embolisation

Country Status (8)

Country Link
US (4) US7462366B2 (de)
EP (1) EP1531874B1 (de)
JP (1) JP2005537070A (de)
AU (1) AU2003270050A1 (de)
CA (1) CA2496612A1 (de)
DE (1) DE60327326D1 (de)
WO (1) WO2004020011A1 (de)
ZA (1) ZA200502434B (de)

Families Citing this family (168)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7713297B2 (en) 1998-04-11 2010-05-11 Boston Scientific Scimed, Inc. Drug-releasing stent with ceramic-containing layer
US7776310B2 (en) 2000-11-16 2010-08-17 Microspherix Llc Flexible and/or elastic brachytherapy seed or strand
US20110301569A1 (en) 2001-01-20 2011-12-08 Gordon Wayne Dyer Methods and apparatus for the CVCS
US7700819B2 (en) 2001-02-16 2010-04-20 Kci Licensing, Inc. Biocompatible wound dressing
US7763769B2 (en) 2001-02-16 2010-07-27 Kci Licensing, Inc. Biocompatible wound dressing
WO2003002243A2 (en) 2001-06-27 2003-01-09 Remon Medical Technologies Ltd. Method and device for electrochemical formation of therapeutic species in vivo
US7462366B2 (en) 2002-03-29 2008-12-09 Boston Scientific Scimed, Inc. Drug delivery particle
US7094369B2 (en) * 2002-03-29 2006-08-22 Scimed Life Systems, Inc. Processes for manufacturing polymeric microspheres
US7053134B2 (en) * 2002-04-04 2006-05-30 Scimed Life Systems, Inc. Forming a chemically cross-linked particle of a desired shape and diameter
US7449236B2 (en) * 2002-08-09 2008-11-11 Boston Scientific Scimed, Inc. Porous polymeric particle comprising polyvinyl alcohol and having interior to surface porosity-gradient
US7842377B2 (en) * 2003-08-08 2010-11-30 Boston Scientific Scimed, Inc. Porous polymeric particle comprising polyvinyl alcohol and having interior to surface porosity-gradient
US8012454B2 (en) 2002-08-30 2011-09-06 Boston Scientific Scimed, Inc. Embolization
US7883490B2 (en) 2002-10-23 2011-02-08 Boston Scientific Scimed, Inc. Mixing and delivery of therapeutic compositions
US20050075625A1 (en) * 2003-07-18 2005-04-07 Kinh-Luan Dao Medical devices
US7976823B2 (en) 2003-08-29 2011-07-12 Boston Scientific Scimed, Inc. Ferromagnetic particles and methods
US20050070990A1 (en) * 2003-09-26 2005-03-31 Stinson Jonathan S. Medical devices and methods of making same
US7901770B2 (en) 2003-11-04 2011-03-08 Boston Scientific Scimed, Inc. Embolic compositions
US20070031339A1 (en) 2003-11-28 2007-02-08 Oskar Axelsson Contrast agents
US20050175709A1 (en) * 2003-12-11 2005-08-11 Baty Ace M.Iii Therapeutic microparticles
US7854756B2 (en) * 2004-01-22 2010-12-21 Boston Scientific Scimed, Inc. Medical devices
US8620406B2 (en) * 2004-01-23 2013-12-31 Boston Scientific Scimed, Inc. Medical devices visible by magnetic resonance imaging
US8992592B2 (en) 2004-12-29 2015-03-31 Boston Scientific Scimed, Inc. Medical devices including metallic films
US7901447B2 (en) 2004-12-29 2011-03-08 Boston Scientific Scimed, Inc. Medical devices including a metallic film and at least one filament
US8998973B2 (en) 2004-03-02 2015-04-07 Boston Scientific Scimed, Inc. Medical devices including metallic films
US8632580B2 (en) 2004-12-29 2014-01-21 Boston Scientific Scimed, Inc. Flexible medical devices including metallic films
US7736671B2 (en) 2004-03-02 2010-06-15 Boston Scientific Scimed, Inc. Embolization
US8591568B2 (en) 2004-03-02 2013-11-26 Boston Scientific Scimed, Inc. Medical devices including metallic films and methods for making same
TWI434676B (zh) 2004-03-19 2014-04-21 Merck Sharp & Dohme 可用x射線看出之藥物遞送裝置
US20050215950A1 (en) * 2004-03-26 2005-09-29 Scimed Life Systems, Inc. Balloon catheter with radiopaque portion
US8173176B2 (en) 2004-03-30 2012-05-08 Boston Scientific Scimed, Inc. Embolization
US20050238870A1 (en) * 2004-04-22 2005-10-27 Marcia Buiser Embolization
US7311861B2 (en) 2004-06-01 2007-12-25 Boston Scientific Scimed, Inc. Embolization
US7585318B2 (en) * 2004-06-18 2009-09-08 Boston Scientific Scimed, Inc. Medical devices and methods of making the same
US7344560B2 (en) 2004-10-08 2008-03-18 Boston Scientific Scimed, Inc. Medical devices and methods of making the same
CA3066594A1 (en) * 2004-10-08 2006-04-20 Georgia Tech Research Corporation Microencapsulation of cells in hydrogels using electrostatic potentials
JP3857295B2 (ja) * 2004-11-10 2006-12-13 三菱電機株式会社 半導体発光素子
US7201918B2 (en) * 2004-11-16 2007-04-10 Microvention, Inc. Compositions, systems and methods for treatment of defects in blood vessels
US8425550B2 (en) 2004-12-01 2013-04-23 Boston Scientific Scimed, Inc. Embolic coils
US20060122694A1 (en) * 2004-12-03 2006-06-08 Stinson Jonathan S Medical devices and methods of making the same
AU2005321543A1 (en) * 2004-12-30 2006-07-06 Cinvention Ag Combination comprising an agent providing a signal, an implant material and a drug
US7727273B2 (en) * 2005-01-13 2010-06-01 Boston Scientific Scimed, Inc. Medical devices and methods of making the same
US7918795B2 (en) 2005-02-02 2011-04-05 Gynesonics, Inc. Method and device for uterine fibroid treatment
US20060177489A1 (en) * 2005-02-07 2006-08-10 Massouda Debora F Attachment of chitosan to surfaces using rehydration process
US8048028B2 (en) * 2005-02-17 2011-11-01 Boston Scientific Scimed, Inc. Reinforced medical balloon
US20060182873A1 (en) * 2005-02-17 2006-08-17 Klisch Leo M Medical devices
US7727555B2 (en) * 2005-03-02 2010-06-01 Boston Scientific Scimed, Inc. Particles
US7858183B2 (en) 2005-03-02 2010-12-28 Boston Scientific Scimed, Inc. Particles
US8435280B2 (en) * 2005-03-31 2013-05-07 Boston Scientific Scimed, Inc. Flexible stent with variable width elements
US7641983B2 (en) * 2005-04-04 2010-01-05 Boston Scientific Scimed, Inc. Medical devices including composites
EA013680B1 (ru) * 2005-04-15 2010-06-30 Бейцзин Шенияо Сайнс Энд Текнолоджи Девелопмент Ко., Лтд. Микросферический васкулярный эмбол на основе альгината натрия, содержащий гинекологическое лекарственное средство, и его получение
US7963287B2 (en) 2005-04-28 2011-06-21 Boston Scientific Scimed, Inc. Tissue-treatment methods
US8071155B2 (en) * 2005-05-05 2011-12-06 Boston Scientific Scimed, Inc. Medical devices and methods of making the same
US20060259126A1 (en) * 2005-05-05 2006-11-16 Jason Lenz Medical devices and methods of making the same
US7854760B2 (en) 2005-05-16 2010-12-21 Boston Scientific Scimed, Inc. Medical devices including metallic films
US7449505B2 (en) * 2005-05-20 2008-11-11 Xerox Corporation Method of making porous microspheres with geometric standard deviation of 1.25 or less
US20060276875A1 (en) * 2005-05-27 2006-12-07 Stinson Jonathan S Medical devices
US20060276910A1 (en) * 2005-06-01 2006-12-07 Jan Weber Endoprostheses
US9463426B2 (en) * 2005-06-24 2016-10-11 Boston Scientific Scimed, Inc. Methods and systems for coating particles
US7778684B2 (en) * 2005-08-08 2010-08-17 Boston Scientific Scimed, Inc. MRI resonator system with stent implant
US20070048383A1 (en) * 2005-08-25 2007-03-01 Helmus Michael N Self-assembled endovascular structures
US20070073374A1 (en) * 2005-09-29 2007-03-29 Anderl Steven F Endoprostheses including nickel-titanium alloys
US8007509B2 (en) 2005-10-12 2011-08-30 Boston Scientific Scimed, Inc. Coil assemblies, components and methods
US8101197B2 (en) 2005-12-19 2012-01-24 Stryker Corporation Forming coils
US8152839B2 (en) 2005-12-19 2012-04-10 Boston Scientific Scimed, Inc. Embolic coils
US7947368B2 (en) 2005-12-21 2011-05-24 Boston Scientific Scimed, Inc. Block copolymer particles
US8840660B2 (en) 2006-01-05 2014-09-23 Boston Scientific Scimed, Inc. Bioerodible endoprostheses and methods of making the same
US7874986B2 (en) 2006-04-20 2011-01-25 Gynesonics, Inc. Methods and devices for visualization and ablation of tissue
US11259825B2 (en) 2006-01-12 2022-03-01 Gynesonics, Inc. Devices and methods for treatment of tissue
US7815571B2 (en) 2006-04-20 2010-10-19 Gynesonics, Inc. Rigid delivery systems having inclined ultrasound and needle
US10058342B2 (en) 2006-01-12 2018-08-28 Gynesonics, Inc. Devices and methods for treatment of tissue
US9357977B2 (en) 2006-01-12 2016-06-07 Gynesonics, Inc. Interventional deployment and imaging system
EP1810698A1 (de) * 2006-01-24 2007-07-25 Biocompatibles UK Limited Prozess zur Herstellung von röntgendichten embolisierenden Mikrosphären
EP2368581B1 (de) * 2006-01-30 2018-08-29 Biosphere Medical, Inc. Poröse intravaskuläre Embolisierungspartikel und zugehörige Verfahren
US20080033366A1 (en) 2006-01-30 2008-02-07 Surgica Corporation Compressible intravascular embolization particles and related methods and delivery systems
US8089029B2 (en) 2006-02-01 2012-01-03 Boston Scientific Scimed, Inc. Bioabsorbable metal medical device and method of manufacture
US20070239256A1 (en) * 2006-03-22 2007-10-11 Jan Weber Medical devices having electrical circuits with multilayer regions
US20070224235A1 (en) 2006-03-24 2007-09-27 Barron Tenney Medical devices having nanoporous coatings for controlled therapeutic agent delivery
US8187620B2 (en) 2006-03-27 2012-05-29 Boston Scientific Scimed, Inc. Medical devices comprising a porous metal oxide or metal material and a polymer coating for delivering therapeutic agents
US8048150B2 (en) 2006-04-12 2011-11-01 Boston Scientific Scimed, Inc. Endoprosthesis having a fiber meshwork disposed thereon
US8206300B2 (en) 2008-08-26 2012-06-26 Gynesonics, Inc. Ablation device with articulated imaging transducer
US10595819B2 (en) 2006-04-20 2020-03-24 Gynesonics, Inc. Ablation device with articulated imaging transducer
JP2009540946A (ja) * 2006-06-20 2009-11-26 ボストン サイエンティフィック リミテッド 複合材料を含む医療器具
US8815275B2 (en) 2006-06-28 2014-08-26 Boston Scientific Scimed, Inc. Coatings for medical devices comprising a therapeutic agent and a metallic material
CA2655793A1 (en) 2006-06-29 2008-01-03 Boston Scientific Limited Medical devices with selective coating
US10675298B2 (en) 2006-07-27 2020-06-09 Boston Scientific Scimed Inc. Particles
WO2008014060A2 (en) * 2006-07-27 2008-01-31 Boston Scientific Limited Microparticle
EP2054537A2 (de) 2006-08-02 2009-05-06 Boston Scientific Scimed, Inc. Endoprothese mit dreidimensionaler desintegrationssteuerung
CA2662808A1 (en) * 2006-09-14 2008-03-20 Boston Scientific Limited Medical devices with drug-eluting coating
EP2081616B1 (de) 2006-09-15 2017-11-01 Boston Scientific Scimed, Inc. Bioerodierbare endoprothesen und herstellungsverfahren dafür
JP2010503494A (ja) 2006-09-15 2010-02-04 ボストン サイエンティフィック リミテッド 生分解性内部人工器官およびその製造方法
CA2663220A1 (en) 2006-09-15 2008-03-20 Boston Scientific Limited Medical devices and methods of making the same
WO2008034047A2 (en) 2006-09-15 2008-03-20 Boston Scientific Limited Endoprosthesis with adjustable surface features
EP2210625B8 (de) 2006-09-15 2012-02-29 Boston Scientific Scimed, Inc. Biologisch erodierbare Endoprothese mit biostabilen anorganischen Schichten
JP2010503468A (ja) * 2006-09-18 2010-02-04 ボストン サイエンティフィック リミテッド 多孔性表面を備えた医療用デバイス
US8002821B2 (en) 2006-09-18 2011-08-23 Boston Scientific Scimed, Inc. Bioerodible metallic ENDOPROSTHESES
US7780798B2 (en) 2006-10-13 2010-08-24 Boston Scientific Scimed, Inc. Medical devices including hardened alloys
US20100311638A1 (en) * 2006-10-27 2010-12-09 Paul Tiege Method for Altering the Shape of Polymer Particles
US8414927B2 (en) 2006-11-03 2013-04-09 Boston Scientific Scimed, Inc. Cross-linked polymer particles
US7981150B2 (en) 2006-11-09 2011-07-19 Boston Scientific Scimed, Inc. Endoprosthesis with coatings
ES2506144T3 (es) 2006-12-28 2014-10-13 Boston Scientific Limited Endoprótesis bioerosionables y procedimiento de fabricación de las mismas
US8431149B2 (en) 2007-03-01 2013-04-30 Boston Scientific Scimed, Inc. Coated medical devices for abluminal drug delivery
US8070797B2 (en) 2007-03-01 2011-12-06 Boston Scientific Scimed, Inc. Medical device with a porous surface for delivery of a therapeutic agent
JP5578655B2 (ja) * 2007-03-02 2014-08-27 ザ ボード オブ トラスティーズ オブ ザ ユニヴァーシティー オブ イリノイ 微粒子による薬物送達
US8067054B2 (en) 2007-04-05 2011-11-29 Boston Scientific Scimed, Inc. Stents with ceramic drug reservoir layer and methods of making and using the same
US7976915B2 (en) 2007-05-23 2011-07-12 Boston Scientific Scimed, Inc. Endoprosthesis with select ceramic morphology
US8211162B2 (en) * 2007-05-25 2012-07-03 Boston Scientific Scimed, Inc. Connector node for durable stent
US8002823B2 (en) 2007-07-11 2011-08-23 Boston Scientific Scimed, Inc. Endoprosthesis coating
US7942926B2 (en) 2007-07-11 2011-05-17 Boston Scientific Scimed, Inc. Endoprosthesis coating
US20090018644A1 (en) * 2007-07-13 2009-01-15 Jan Weber Boron-Enhanced Shape Memory Endoprostheses
US7604662B2 (en) * 2007-07-13 2009-10-20 Boston Scientific Scimed, Inc. Endoprostheses containing boride intermetallic phases
EP2187988B1 (de) 2007-07-19 2013-08-21 Boston Scientific Limited Endoprothese mit nicht verschmutzender oberfläche
US8815273B2 (en) 2007-07-27 2014-08-26 Boston Scientific Scimed, Inc. Drug eluting medical devices having porous layers
US7931683B2 (en) 2007-07-27 2011-04-26 Boston Scientific Scimed, Inc. Articles having ceramic coated surfaces
WO2009018340A2 (en) 2007-07-31 2009-02-05 Boston Scientific Scimed, Inc. Medical device coating by laser cladding
EP2185103B1 (de) 2007-08-03 2014-02-12 Boston Scientific Scimed, Inc. Überzug für ein medizinprodukt mit vergrösserter oberfläche
US20090068279A1 (en) * 2007-09-12 2009-03-12 Boston Scientific Scimed, Inc. Microspheres with surface projections
US8052745B2 (en) 2007-09-13 2011-11-08 Boston Scientific Scimed, Inc. Endoprosthesis
US20090088723A1 (en) * 2007-09-28 2009-04-02 Accessclosure, Inc. Apparatus and methods for treating pseudoaneurysms
WO2009046281A2 (en) * 2007-10-05 2009-04-09 Boston Scientific Scimed, Inc. Injectable particles
US9107828B2 (en) * 2007-10-05 2015-08-18 Boston Scientific Scimed, Inc. Multi-component particles for injection and processes for forming the same
US20090092675A1 (en) * 2007-10-05 2009-04-09 Boston Scientific Scimed, Inc. Compositions containing multiple polymers and particles made using the compositions
US8088072B2 (en) 2007-10-12 2012-01-03 Gynesonics, Inc. Methods and systems for controlled deployment of needles in tissue
US8216632B2 (en) 2007-11-02 2012-07-10 Boston Scientific Scimed, Inc. Endoprosthesis coating
US8029554B2 (en) 2007-11-02 2011-10-04 Boston Scientific Scimed, Inc. Stent with embedded material
US7938855B2 (en) 2007-11-02 2011-05-10 Boston Scientific Scimed, Inc. Deformable underlayer for stent
US8821931B2 (en) 2007-11-16 2014-09-02 Bridgestone Corporation Micro-particles containing a 3-D polymeric structure
US20090169641A1 (en) * 2007-12-26 2009-07-02 Boston Scientifice Scimed, Inc. Compressible particles
WO2009086067A2 (en) * 2007-12-28 2009-07-09 Boston Scientific Scimed, Inc. Particles for injection and processes fo forming the same
WO2009086076A2 (en) * 2007-12-28 2009-07-09 Boston Scientific Scimed, Inc. Particles for injection and processes for forming the same
WO2009086098A1 (en) * 2007-12-28 2009-07-09 Boston Scientific Scimed, Inc. Porous microparticles for injection and processes for forming the same
US20090169591A1 (en) * 2007-12-28 2009-07-02 Boston Scientific Scimed, Inc. Medical articles for the treatment of tumors
WO2009131911A2 (en) 2008-04-22 2009-10-29 Boston Scientific Scimed, Inc. Medical devices having a coating of inorganic material
WO2009132176A2 (en) 2008-04-24 2009-10-29 Boston Scientific Scimed, Inc. Medical devices having inorganic particle layers
US7998192B2 (en) 2008-05-09 2011-08-16 Boston Scientific Scimed, Inc. Endoprostheses
US8236046B2 (en) 2008-06-10 2012-08-07 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
EP2303350A2 (de) 2008-06-18 2011-04-06 Boston Scientific Scimed, Inc. Endoprothesen-beschichtung
US7985252B2 (en) 2008-07-30 2011-07-26 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
US8382824B2 (en) 2008-10-03 2013-02-26 Boston Scientific Scimed, Inc. Medical implant having NANO-crystal grains with barrier layers of metal nitrides or fluorides
JP2012507562A (ja) * 2008-10-30 2012-03-29 ダビド リウ 微小球性多孔質生体適合性足場並びにその製造方法及び装置
US8231980B2 (en) 2008-12-03 2012-07-31 Boston Scientific Scimed, Inc. Medical implants including iridium oxide
US20100217370A1 (en) * 2009-02-20 2010-08-26 Boston Scientific Scimed, Inc. Bioerodible Endoprosthesis
US8262574B2 (en) 2009-02-27 2012-09-11 Gynesonics, Inc. Needle and tine deployment mechanism
EP2403546A2 (de) 2009-03-02 2012-01-11 Boston Scientific Scimed, Inc. Selbstpufferende medizinische implantate
US8071156B2 (en) 2009-03-04 2011-12-06 Boston Scientific Scimed, Inc. Endoprostheses
US8287937B2 (en) 2009-04-24 2012-10-16 Boston Scientific Scimed, Inc. Endoprosthese
US20100292776A1 (en) * 2009-05-14 2010-11-18 Boston Scientific Scimed, Inc. Bioerodible Endoprosthesis
CN102741336B (zh) 2009-12-01 2014-03-19 株式会社普利司通 改性橡胶组合物和制备方法
US20110160839A1 (en) * 2009-12-29 2011-06-30 Boston Scientific Scimed, Inc. Endoprosthesis
US8668732B2 (en) 2010-03-23 2014-03-11 Boston Scientific Scimed, Inc. Surface treated bioerodible metal endoprostheses
US8709072B2 (en) 2010-05-13 2014-04-29 Boston Scientific Scimed, Inc. Endoprosthesis
JP5834071B2 (ja) 2010-05-14 2015-12-16 ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. ステント
WO2012006101A2 (en) 2010-06-28 2012-01-12 The General Hospital Corporation Blood substitutes and uses thereof
US8765725B2 (en) 2012-05-08 2014-07-01 Aciex Therapeutics, Inc. Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof
CA2872845C (en) 2012-05-08 2021-11-09 Aciex Therapeutics, Inc. Preparation of nanocrystals of fluticasone propionate
ES2655656T3 (es) * 2012-05-24 2018-02-21 Biosphere Medical Inc. Biomateriales adecuados para usar como implantes detectables mediante imagen de resonancia magnética, eluyentes de fármacos para oclusión vascular
EP2882459A1 (de) 2012-08-10 2015-06-17 University of North Texas Health Science Center Wirkstofffreisetzungsvehikel mit konjugaten zwischen gerichteten polyaminosäuren und fettsäuren
US9815865B2 (en) 2013-01-07 2017-11-14 Nicox Ophthalmics, Inc. Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof
KR102505172B1 (ko) 2013-09-19 2023-02-28 마이크로벤션, 인코포레이티드 중합체 필름
JP6405369B2 (ja) 2013-09-19 2018-10-17 テルモ株式会社 ポリマー粒子
EP3065719A4 (de) 2013-11-08 2017-08-09 Terumo Corporation Polymerpartikel
WO2015161211A1 (en) * 2014-04-17 2015-10-22 Boston Scientific Scimed, Inc. Devices and methods for therapeutic heat treatment
CN104383357A (zh) * 2014-10-30 2015-03-04 四川金堂海纳生物医药技术研究所 一种治疗声带麻痹的汤剂药物及制备方法
WO2016154592A1 (en) 2015-03-26 2016-09-29 Microvention, Inc. Embiolic particles
CN107708736A (zh) 2015-06-15 2018-02-16 波士顿科学国际有限公司 用于治疗性热处理的装置和方法
JP6866298B2 (ja) 2015-11-24 2021-04-28 Jsr株式会社 多孔質粒子の製造方法、多孔質粒子、担体、カラム、及び標的物質の分離方法
EP3518994B1 (de) 2016-09-28 2024-02-07 Terumo Corporation Polymerpartikel
AU2017359338B2 (en) 2016-11-11 2022-09-08 Gynesonics, Inc. Controlled treatment of tissue and dynamic interaction with, and comparison of, tissue and/or treatment data
WO2019169108A1 (en) * 2018-02-28 2019-09-06 Celista Pharmaceuticals Llc Oxycodone and methylnaltrexone multi-particulates and suspensions containing them

Family Cites Families (341)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2275154A (en) * 1940-07-10 1942-03-03 United Drug Company Method for making capsules
US2609347A (en) 1948-05-27 1952-09-02 Wilson Christopher Lumley Method of making expanded polyvinyl alcohol-formaldehyde reaction product and product resulting therefrom
JPS4820019B1 (de) * 1969-06-05 1973-06-18
US3737398A (en) 1969-11-13 1973-06-05 D Yamaguchi Method of making a polyvinyl acetal sponge buff
CS179075B1 (en) 1974-11-26 1977-10-31 Stoy Vladimir Mode of manufacture of spherical particles from polymer
US4076640A (en) * 1975-02-24 1978-02-28 Xerox Corporation Preparation of spheroidized particles
US3957933A (en) * 1975-03-05 1976-05-18 General Atomic Company Apparatus for producing microspherical particles and method for operating such apparatus
JPS51135958A (en) 1975-05-20 1976-11-25 Fuji Photo Film Co Ltd Method of making fine powder polymer having pores
US4025686A (en) * 1975-06-26 1977-05-24 Owens-Corning Fiberglas Corporation Molded composite article and method for making the article
US4034759A (en) 1975-08-27 1977-07-12 Xomed, Inc. Moisture-expandable prosthesis
US4098728A (en) 1976-01-02 1978-07-04 Solomon Rosenblatt Medical surgical sponge and method of making same
US4055377A (en) 1976-08-03 1977-10-25 Minnesota Mining And Manufacturing Company Magnetically orientable retroreflectorization particles
GB1591924A (en) * 1976-10-25 1981-07-01 Berger Jenson & Nicholson Ltd Polymer aggregates
US4159719A (en) 1977-05-09 1979-07-03 Xomed, Inc. Moisture-expandable ear wick
ES478736A1 (es) 1978-03-23 1979-06-01 Hoechst Ag Procedimiento para la preparacion de un granulado de poli( alcohol vinilico) que contiene agente plasificante.
DE2834539A1 (de) * 1978-08-07 1980-02-21 Basf Ag Makroporoese polymere als traegermaterial zur kovalenten bindung von proteinen
US4793980A (en) 1978-09-21 1988-12-27 Torobin Leonard B Hollow porous microspheres as substrates and containers for catalyst
US4243794A (en) * 1978-10-10 1981-01-06 Minnesota Mining And Manufacturing Company Mixture of rough and spheroidized resin particles
US4198318A (en) * 1978-11-24 1980-04-15 Conoco, Inc. Production of high strength alumina spheres by hydrogelling corresponding slurries
US4268495A (en) * 1979-01-08 1981-05-19 Ethicon, Inc. Injectable embolization and occlusion solution
US4246208A (en) * 1979-03-22 1981-01-20 Xerox Corporation Dust-free plasma spheroidization
US4346712A (en) 1979-04-06 1982-08-31 Kuraray Company, Ltd. Releasable balloon catheter
HU184722B (en) 1980-02-18 1984-10-29 Laszlo Lazar Therapeutically suitable silicone rubber mixture and therapeuticaid
US4271281A (en) 1980-05-29 1981-06-02 American Hoechst Corporation Process for preparing styrenic polymer particles
CA1113532A (en) * 1980-05-30 1981-12-01 Bernard Desourdy Endless track assembly
DE3031737A1 (de) * 1980-08-22 1982-04-01 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von perlpolymerisaten einheitlicher teilchengroesse
CA1166413A (en) * 1980-10-30 1984-05-01 Edward E. Timm Process and apparatus for preparing uniform size polymer beads
US4681119A (en) 1980-11-17 1987-07-21 Schering Aktiengesellschaft Method of production and use of microbubble precursors
US4442843A (en) * 1980-11-17 1984-04-17 Schering, Ag Microbubble precursors and methods for their production and use
US4657756A (en) * 1980-11-17 1987-04-14 Schering Aktiengesellschaft Microbubble precursors and apparatus for their production and use
NZ199916A (en) 1981-03-11 1985-07-12 Unilever Plc Low density polymeric block material for use as carrier for included liquids
US4413070A (en) 1981-03-30 1983-11-01 California Institute Of Technology Polyacrolein microspheres
US4622362A (en) 1981-03-30 1986-11-11 California Institute Of Technology Polyacrolein microspheres
US4678814A (en) 1981-03-30 1987-07-07 California Institute Of Technology Polyacrolein microspheres
CA1177811A (en) 1981-04-13 1984-11-13 Theo G. Spek Process for the preparation of silica particles; silica particles with a narrow pore diameter distribution, catalysts made therefrom and use of these catalysts
US4428869A (en) * 1981-08-20 1984-01-31 International Flavors & Fragrances Inc. Cologne consisting of microcapsule suspension
US4456693A (en) 1982-03-08 1984-06-26 W. R. Grace & Co. Hydrocracking catalyst
US4452773A (en) 1982-04-05 1984-06-05 Canadian Patents And Development Limited Magnetic iron-dextran microspheres
US4472552A (en) 1982-09-27 1984-09-18 W. R. Grace & Co. Continuous process for making solid, free-flowing water dispersible PVA-aldehyde reaction product
US4459145A (en) 1982-09-30 1984-07-10 The United States Of America As Represented By The United States Department Of Energy Fabrication of glass microspheres with conducting surfaces
JPS59131355A (ja) 1983-01-17 1984-07-28 森下仁丹株式会社 多重軟カプセルの製法
US4515906A (en) * 1983-02-28 1985-05-07 Bend Research, Inc. Anisotropic microporous supports impregnated with polymeric ion-exchange materials
DE3313947A1 (de) 1983-04-15 1984-10-18 Schering AG, 1000 Berlin und 4709 Bergkamen Mikropartikel und gasblaeschen enthaltende ultraschall-kontrastmittel
DE3834705A1 (de) 1988-10-07 1990-04-12 Schering Ag Ultraschallkontrastmittel aus gasblaeschen und fettsaeure enthaltenden mikropartikeln
DE3313946A1 (de) 1983-04-15 1984-10-18 Schering AG, 1000 Berlin und 4709 Bergkamen Mikropartikel und gasblaeschen enthaltende ultraschall-kontrastmittel
CA1225585A (en) * 1983-06-30 1987-08-18 Maria T. Litvinova Composition for embolization of blood vessels
US4492720A (en) * 1983-11-15 1985-01-08 Benjamin Mosier Method of preparing microspheres for intravascular delivery
US4573967A (en) * 1983-12-06 1986-03-04 Eli Lilly And Company Vacuum vial infusion system
US4671954A (en) 1983-12-13 1987-06-09 University Of Florida Microspheres for incorporation of therapeutic substances and methods of preparation thereof
US4551436A (en) 1984-04-11 1985-11-05 General Electric Company Fabrication of small dense silicon carbide spheres
DE3414924A1 (de) 1984-04-19 1985-10-31 Klaus Dr.med. Dr.med.habil. 8000 München Draenert Beschichtetes verankerungsteil fuer implantate
US4674480A (en) 1984-05-25 1987-06-23 Lemelson Jerome H Drug compositions and methods of applying same
FR2566384B1 (fr) * 1984-06-21 1986-09-05 Saint Gobain Vitrage Perfectionnements aux techniques de production de microspheres en verre
DE3527482A1 (de) 1984-07-31 1986-02-06 Fuji Spinning Co., Ltd., Tokio/Tokyo Verfahren zum herstellen von koernigem poroesen chitosan
GB8419708D0 (en) * 1984-08-02 1984-09-05 Shell Int Research Preparation of silica spheres
US4623706A (en) 1984-08-23 1986-11-18 The Dow Chemical Company Process for preparing uniformly sized polymer particles by suspension polymerization of vibratorily excited monomers in a gaseous or liquid stream
US4629464A (en) 1984-09-25 1986-12-16 Tdk Corporation Porous hydroxyapatite material for artificial bone substitute
JPS61101242A (ja) 1984-10-22 1986-05-20 Showa Denko Kk 被覆物の製造方法
US4789501A (en) * 1984-11-19 1988-12-06 The Curators Of The University Of Missouri Glass microspheres
US4675113A (en) 1984-11-28 1987-06-23 University Patents, Inc. Affinity chromatography using dried calcium alginate-magnetite separation media in a magnetically stabilized fluidized bed
DE3568442D1 (en) 1984-12-06 1989-04-06 Kanegafuchi Chemical Ind A method of preparation of droplets
US5106903A (en) * 1984-12-17 1992-04-21 Lehigh University Preparation of large particle size monodisperse latexes
US4897255A (en) * 1985-01-14 1990-01-30 Neorx Corporation Metal radionuclide labeled proteins for diagnosis and therapy
JPH0678460B2 (ja) * 1985-05-01 1994-10-05 株式会社バイオマテリアル・ユニバース 多孔質透明ポリビニルアルユールゲル
JPS61293911A (ja) * 1985-06-24 1986-12-24 Teisan Seiyaku Kk 徐放化製剤
SE459005B (sv) * 1985-07-12 1989-05-29 Aake Rikard Lindahl Saett att framstaella sfaeriska polymerpartiklar
USH915H (en) 1985-07-22 1991-05-07 Gibbs Marylu B Controlled macroporous copolymer properties by removal of impurities in the diluent
US4742086A (en) 1985-11-02 1988-05-03 Lion Corporation Process for manufacturing porous polymer
DE3543348A1 (de) 1985-12-07 1987-06-11 Bayer Ag Perlfoermige vernetzte, epoxy- und basische aminogruppen aufweisende mischpolymerisate, verfahren zu ihrer herstellung und ihre verwendung
JPS62169723A (ja) * 1986-01-22 1987-07-25 Teisan Seiyaku Kk 徐放化製剤
GB8610024D0 (en) 1986-04-24 1986-05-29 Unilever Plc Porous structures
US4929400A (en) 1986-04-28 1990-05-29 California Institute Of Technology Production of monodisperse, polymeric microspheres
US5262176A (en) * 1986-07-03 1993-11-16 Advanced Magnetics, Inc. Synthesis of polysaccharide covered superparamagnetic oxide colloids
JPS6317904A (ja) 1986-07-09 1988-01-25 Mitsubishi Chem Ind Ltd 多孔質架橋ポリビニルアルコ−ル粒子の製造法
US4743507A (en) 1986-09-12 1988-05-10 Franses Elias I Nonspherical microparticles and method therefor
EP0265061B1 (de) 1986-09-18 1992-01-08 London School of Pharmacy Innovations Ltd Arzneiformulierung
US5114421A (en) 1986-09-22 1992-05-19 Polak Robert B Medicament container/dispenser assembly
CA1287459C (en) 1986-10-01 1991-08-13 Mukesh Jain Process for the preparation of hollow microspheres
US4859711A (en) 1986-10-01 1989-08-22 Alcan International Limited Hollow microspheres
US5263992A (en) 1986-10-17 1993-11-23 Bio-Metric Systems, Inc. Biocompatible device with covalently bonded biocompatible agent
DE3787700T3 (de) 1986-10-29 1998-12-24 Kanegafuchi Chemical Ind Gleichförmige Polymerteilchen.
US5292814A (en) * 1987-04-29 1994-03-08 Ernst Bayer Process for the preparation of monodispersed polymer beads
US4795741A (en) * 1987-05-06 1989-01-03 Biomatrix, Inc. Compositions for therapeutic percutaneous embolization and the use thereof
GB8713263D0 (en) 1987-06-05 1987-07-08 Unilever Plc Spheroidal silica
JPH0612993B2 (ja) 1987-08-10 1994-02-23 株式会社クラレ 球状の微生物固定化成形物の製造法
US4819637A (en) * 1987-09-01 1989-04-11 Interventional Therapeutics Corporation System for artificial vessel embolization and devices for use therewith
JPH0762054B2 (ja) 1987-10-13 1995-07-05 倉敷紡績株式会社 架橋重合体粒子
US4850978A (en) 1987-10-29 1989-07-25 Baxter International Inc. Drug delivery cartridge with protective cover
US4804366A (en) * 1987-10-29 1989-02-14 Baxter International Inc. Cartridge and adapter for introducing a beneficial agent into an intravenous delivery system
US4981625A (en) * 1988-03-14 1991-01-01 California Institute Of Technology Monodisperse, polymeric microspheres produced by irradiation of slowly thawing frozen drops
FR2634376B1 (fr) * 1988-07-21 1992-04-17 Farmalyoc Nouvelle forme unitaire, solide et poreuse comprenant des microparticules et/ou des nanoparticules, ainsi que sa preparation
WO1990001969A1 (en) 1988-08-24 1990-03-08 Slepian Marvin J Biodegradable polymeric endoluminal sealing
DE3829938A1 (de) 1988-09-02 1990-03-29 Hermann Hofmann Organo-mineralischer duenger und verfahren zu seiner herstellung
US4933372A (en) 1988-09-26 1990-06-12 Supelco, Inc. Porous rigid resins and process of preparation
US5047438A (en) 1988-09-26 1991-09-10 Supelco, Inc. Porous rigid resins and process of preparation
US5681576A (en) 1988-11-16 1997-10-28 Mdv Technologies, Inc. Method and composition for post surgical adhesion reduction
DE3841401A1 (de) 1988-12-08 1990-06-13 Martin Lemperle Alloplastisches implantat
US5258028A (en) 1988-12-12 1993-11-02 Ersek Robert A Textured micro implants
US4946899A (en) 1988-12-16 1990-08-07 The University Of Akron Thermoplastic elastomers of isobutylene and process of preparation
GB8900376D0 (en) 1989-01-09 1989-03-08 Nycomed As Iodinated esters
US5091205A (en) * 1989-01-17 1992-02-25 Union Carbide Chemicals & Plastics Technology Corporation Hydrophilic lubricious coatings
FR2641692A1 (fr) * 1989-01-17 1990-07-20 Nippon Zeon Co Bouchon de fermeture d'une breche pour application medicale et dispositif pour bouchon de fermeture l'utilisant
US5032117A (en) 1989-01-30 1991-07-16 Motta Louis J Tandem syringe
GB8905934D0 (en) * 1989-03-15 1989-04-26 Dow Europ Sa A process for preparing adsorptive porous resin beads
US5888930A (en) * 1989-03-27 1999-03-30 Bend Research, Inc. Asymmetric microporous beads for controlled release
US5354290A (en) 1989-05-31 1994-10-11 Kimberly-Clark Corporation Porous structure of an absorbent polymer
CA2017570C (en) * 1989-05-31 2000-12-19 James R. Gross Porous structure of an absorbent polymer
US5007940A (en) * 1989-06-09 1991-04-16 American Medical Systems, Inc. Injectable polymeric bodies
US5158573A (en) 1989-06-09 1992-10-27 American Medical Systems, Inc. Injectable polymeric bodies
US5116387A (en) 1989-06-09 1992-05-26 American Medical Systems, Inc. Preparation of injectable polymeric bodies
US5190760A (en) * 1989-07-08 1993-03-02 Coopers Animal Health Limited Solid pharmaceutical composition
US5698271A (en) * 1989-08-22 1997-12-16 Immunivest Corporation Methods for the manufacture of magnetically responsive particles
US5253991A (en) 1989-11-20 1993-10-19 Sumitomo Cement Co., Ltd. Apparatus for producing spheroidal inorganic particulate material
US5542935A (en) 1989-12-22 1996-08-06 Imarx Pharmaceutical Corp. Therapeutic delivery systems related applications
US5580575A (en) 1989-12-22 1996-12-03 Imarx Pharmaceutical Corp. Therapeutic drug delivery systems
US5922304A (en) 1989-12-22 1999-07-13 Imarx Pharmaceutical Corp. Gaseous precursor filled microspheres as magnetic resonance imaging contrast agents
US5585112A (en) 1989-12-22 1996-12-17 Imarx Pharmaceutical Corp. Method of preparing gas and gaseous precursor-filled microspheres
US5469854A (en) 1989-12-22 1995-11-28 Imarx Pharmaceutical Corp. Methods of preparing gas-filled liposomes
US6306427B1 (en) 1989-12-28 2001-10-23 Rhone-Poulenc Nutrition Animale Pellets containing active ingredients protected against degradation in the rumen of ruminants
US5435645A (en) 1989-12-29 1995-07-25 Tecres Spa Process and apparatus for the mixing and direct emplacement of a two-component bone cement
US5147937A (en) 1990-03-22 1992-09-15 Rohm And Haas Company Process for making controlled, uniform-sized particles in the 1 to 50 micrometer range
US5556610A (en) 1992-01-24 1996-09-17 Bracco Research S.A. Gas mixtures useful as ultrasound contrast media, contrast agents containing the media and method
JPH03297475A (ja) * 1990-04-16 1991-12-27 Ken Ishihara 共振音波により薬物の放出を制御する方法
US5514090A (en) 1990-04-24 1996-05-07 Science Incorporated Closed drug delivery system
US5137928A (en) 1990-04-26 1992-08-11 Hoechst Aktiengesellschaft Ultrasonic contrast agents, processes for their preparation and the use thereof as diagnostic and therapeutic agents
CA2016870C (en) 1990-05-15 1994-03-29 Arnie Drudik Dispenser for storing and mixing several components
AU636481B2 (en) 1990-05-18 1993-04-29 Bracco International B.V. Polymeric gas or air filled microballoons usable as suspensions in liquid carriers for ultrasonic echography
JP2514087Y2 (ja) * 1990-05-25 1996-10-16 幸三 牧田 離脱式両端逆止弁付きバル―ン
US6291605B1 (en) 1990-06-06 2001-09-18 Clarence S. Freeman Polymerization process with spraying step
WO1991019483A1 (en) 1990-06-20 1991-12-26 Advanced Polymer Systems, Inc. Compositions and methods for the controlled release of soluble active substances
JP2931879B2 (ja) * 1990-06-27 1999-08-09 レンゴー株式会社 キチン又は脱アセチル化キチンとセルロースからなるセルロース系多孔質球状粒子及びその製造法
ATE130517T1 (de) 1990-08-08 1995-12-15 Takeda Chemical Industries Ltd Intravaskulär embolisierendes mittel mit gehalt an einem die angiogenesis hemmenden stoff.
US5484584A (en) * 1990-10-02 1996-01-16 Board Of Regents, The University Of Texas System Therapeutic and diagnostic use of modified polymeric microcapsules
US5149543A (en) 1990-10-05 1992-09-22 Massachusetts Institute Of Technology Ionically cross-linked polymeric microcapsules
US5120349A (en) 1990-12-07 1992-06-09 Landec Labs, Inc. Microcapsule having temperature-dependent permeability profile
US5171214A (en) 1990-12-26 1992-12-15 Abbott Laboratories Drug storage and delivery system
US5171217A (en) 1991-02-28 1992-12-15 Indiana University Foundation Method for delivery of smooth muscle cell inhibitors
US5147631A (en) 1991-04-30 1992-09-15 Du Pont Merck Pharmaceutical Company Porous inorganic ultrasound contrast agents
FR2676927B1 (fr) 1991-05-29 1995-06-23 Ibf Microspheres utilisables pour les occlusions vasculaires therapeutiques et solutions injectables les contenant.
DK0586524T3 (de) 1991-06-03 1997-05-20 Nycomed Imaging As
GB9116610D0 (en) 1991-08-01 1991-09-18 Danbiosyst Uk Preparation of microparticles
US5216096A (en) 1991-09-24 1993-06-01 Japan Synthetic Rubber Co., Ltd. Process for the preparation of cross-linked polymer particles
US5811447A (en) * 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
ATE154241T1 (de) * 1991-10-01 1997-06-15 Takeda Chemical Industries Ltd Mikropartikeln-zusammenfassung zur verlängerten freigabe und herstellung derselbe
JPH0718357A (ja) * 1991-10-02 1995-01-20 Yasubumi Furuya 複合機能材料素子
JP3356447B2 (ja) * 1991-10-16 2002-12-16 テルモ株式会社 乾燥高分子ゲルからなる血管病変塞栓材料
US5258042A (en) 1991-12-16 1993-11-02 Henry Ford Health System Intravascular hydrogel implant
DE69226203T2 (de) * 1991-12-20 1998-12-10 Allied Signal Inc Materialien mit niedriger dichte und hoher spezifischer oberflaeche und daraus geformte artikel zur verwendung in der metallrueckgewinnung
US5260002A (en) 1991-12-23 1993-11-09 Vanderbilt University Method and apparatus for producing uniform polymeric spheres
CA2125647C (en) 1991-12-24 1997-12-30 Joseph A. Antonelli Dual stabilized microparticles
GB9200388D0 (en) 1992-01-09 1992-02-26 Nycomed As Improvements in or relating to contrast agents
GB9200391D0 (en) 1992-01-09 1992-02-26 Nycomed As Improvements in or relating to contrast agents
US6537574B1 (en) 1992-02-11 2003-03-25 Bioform, Inc. Soft tissue augmentation material
US5480644A (en) * 1992-02-28 1996-01-02 Jsf Consultants Ltd. Use of injectable biomaterials for the repair and augmentation of the anal sphincters
ES2135466T3 (es) 1992-03-06 1999-11-01 Nycomed Imaging As Mejoras introducidas en agentes de contraste.
JP3004724B2 (ja) 1992-04-06 2000-01-31 ユーロプラスティ インコーポレイテッド ミクロ粒子注入による逆流障害の処置
DE69306844T2 (de) 1992-04-10 1997-07-10 Mitsubishi Chem Corp Verfahren zur Herstellung von kugelförmigen vernetzten Acrylnitril-Copolymerisaten
US6235313B1 (en) 1992-04-24 2001-05-22 Brown University Research Foundation Bioadhesive microspheres and their use as drug delivery and imaging systems
AU4198793A (en) * 1992-07-24 1994-01-27 Takeda Chemical Industries Ltd. Microparticle preparation and production thereof
US5514379A (en) * 1992-08-07 1996-05-07 The General Hospital Corporation Hydrogel compositions and methods of use
US5807323A (en) 1992-08-13 1998-09-15 Science Incorporated Mixing and delivery syringe assembly
US6592859B1 (en) 1992-08-20 2003-07-15 Ethicon, Inc. Controlled expansion sphincter augmentation media
US5512604A (en) * 1992-08-28 1996-04-30 The Dow Chemical Company Porous copolymers having a cellular polymeric structure suitable for preparing ion-exchange resins and adsorbents
WO1994006477A1 (en) * 1992-09-16 1994-03-31 Holmes, Michael, John Improvements in or relating to contrast agents
WO1994006460A1 (en) 1992-09-21 1994-03-31 Vitaphore Corporation Embolization plugs for blood vessels
DE4232755A1 (de) 1992-09-26 1994-03-31 Schering Ag Mikropartikelpräparationen aus biologisch abbaubaren Mischpolymeren
KR960001417B1 (ko) 1992-09-26 1996-01-27 한국과학기술원 개선된 다공성 고분자 담체의 합성방법
GB9221329D0 (en) 1992-10-10 1992-11-25 Delta Biotechnology Ltd Preparation of further diagnostic agents
US5382260A (en) 1992-10-30 1995-01-17 Interventional Therapeutics Corp. Embolization device and apparatus including an introducer cartridge and method for delivering the same
US5369163A (en) 1992-11-13 1994-11-29 Rohm And Haas Company Process for preparing large dimension emulsion polymer particles, polymer product and uses thereof
US5690666A (en) 1992-11-18 1997-11-25 Target Therapeutics, Inc. Ultrasoft embolism coils and process for using them
US5349957A (en) * 1992-12-02 1994-09-27 Sterling Winthrop Inc. Preparation and magnetic properties of very small magnetite-dextran particles
JP3256583B2 (ja) 1992-12-10 2002-02-12 株式会社リコー 電子写真用トナー及びその製法
US5288763A (en) * 1992-12-23 1994-02-22 The Johns Hopkins University School Of Medicine Porous, polymer beads and process of their preparation
US6482436B1 (en) 1993-01-29 2002-11-19 Ferx Incorporated Magnetically responsive composition
US5328936A (en) 1993-02-01 1994-07-12 Rohm And Haas Company Polymerization process for making porous polymeric particles
US6090925A (en) 1993-03-09 2000-07-18 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
US5320639A (en) 1993-03-12 1994-06-14 Meadox Medicals, Inc. Vascular plug delivery system
US5567415A (en) 1993-05-12 1996-10-22 The Board Of Regents Of The University Of Nebraska Ultrasound contrast agents and methods for their manufacture and use
US5701899A (en) 1993-05-12 1997-12-30 The Board Of Regents Of The University Of Nebraska Perfluorobutane ultrasound contrast agent and methods for its manufacture and use
US5695740A (en) 1993-05-12 1997-12-09 The Board Of Regents Of The University Of Nebraska Perfluorocarbon ultrasound contrast agent comprising microbubbles containing a filmogenic protein and a saccharide
US5344867A (en) 1993-06-14 1994-09-06 The Bfgoodrich Company Vinylidene chloride emulsion interpolymer composition
US5716981A (en) * 1993-07-19 1998-02-10 Angiogenesis Technologies, Inc. Anti-angiogenic compositions and methods of use
ATE154757T1 (de) 1993-07-19 1997-07-15 Angiotech Pharm Inc Anti-angiogene mittel und verfahren zu deren verwendung
US5397303A (en) * 1993-08-06 1995-03-14 River Medical, Inc. Liquid delivery device having a vial attachment or adapter incorporated therein
US5398851A (en) 1993-08-06 1995-03-21 River Medical, Inc. Liquid delivery device
US5443495A (en) 1993-09-17 1995-08-22 Scimed Lifesystems Inc. Polymerization angioplasty balloon implant device
US5531716A (en) 1993-09-29 1996-07-02 Hercules Incorporated Medical devices subject to triggered disintegration
DE1258262T1 (de) * 1993-10-28 2003-04-10 Medrad Inc System zur Kontrastmittelabgabe
PT682530E (pt) 1993-12-15 2003-06-30 Bracco Research Sa Misturas de gases uteis como meios de contraste para ultrassons
WO1995019841A1 (en) 1994-01-21 1995-07-27 Bruce Nathaniel Gray Particulate material
WO1995022318A1 (en) 1994-02-17 1995-08-24 Pankaj Modi Drugs, vaccines and hormones in polylactide coated microspheres
US5569468A (en) 1994-02-17 1996-10-29 Modi; Pankaj Vaccine delivery system for immunization, using biodegradable polymer microspheres
US5417982A (en) 1994-02-17 1995-05-23 Modi; Pankaj Controlled release of drugs or hormones in biodegradable polymer microspheres
WO1995025480A1 (en) 1994-03-18 1995-09-28 Cook Incorporated Helical embolization coil
US5431174A (en) 1994-04-04 1995-07-11 Via Medical Corporation Method of fluid delivery and collection
WO1995029661A1 (de) 1994-04-28 1995-11-09 Primed Halberstadt Medizintechnik Gmbh Einstückige appliziervorrichtung zur kontaminationsfreien verabreichung von arzneimitteln (zytostatika)
US5534589A (en) * 1994-05-04 1996-07-09 Minnesota Mining And Manufacturing Company Repulpable plastic films
WO1995031485A1 (en) 1994-05-15 1995-11-23 Pharmacia Biotech Ab A method of manufacturing particles, and particles that can be produced in accordance with the method
JP2535785B2 (ja) 1994-06-03 1996-09-18 工業技術院長 血管塞栓剤
US5583162A (en) 1994-06-06 1996-12-10 Biopore Corporation Polymeric microbeads and method of preparation
US5639710A (en) 1994-07-06 1997-06-17 Zeneca Limited Solid microspheres for agriculturally active compounds and process for their production
ES2096521B1 (es) 1994-08-10 1997-11-16 Univ La Laguna Microesferas de polimeros sinteticos biodegradables en la fabricacion y elaboracion de equipos reactivos para la preparacion de medicamentos radiofarmacos.
WO1996004954A1 (de) 1994-08-17 1996-02-22 Boston Scientific Corporation Implantat, implantationsverfahren und applikationsvorrichtung
US5827531A (en) 1994-12-02 1998-10-27 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Microcapsules and methods for making
US6099864A (en) 1994-12-02 2000-08-08 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration In situ activation of microcapsules
DK175166B1 (da) * 1995-01-03 2004-06-21 Cook William Europ Fremgangsmåde til fremstilling af et aggregat til placering af en embolisationscoil i det vaskulære system og et sådant aggregat samt et apparat til fremføring af aggregatet
JP3625837B2 (ja) * 1995-01-27 2005-03-02 シメッド ライフ システムズ,インコーポレイテッド 塞栓装置
US6179817B1 (en) * 1995-02-22 2001-01-30 Boston Scientific Corporation Hybrid coating for medical devices
EP0730847B1 (de) 1995-03-07 2001-05-23 Menlo Care Inc. Mittel zur Verbesserung der Schliessmuskelfunktion mit kontrollierter Ausdehnung
US5637087A (en) 1995-03-22 1997-06-10 Abbott Laboratories Prefilled, two-constituent syringe
US5785682A (en) 1995-03-22 1998-07-28 Abbott Laboratories Pre-filled syringe drug delivery system
US5569193A (en) 1995-03-22 1996-10-29 Abbott Laboratories Syringe system accommodating separately storable prefilled containers for two constituents
US5876372A (en) * 1995-03-22 1999-03-02 Abbott Laboratories Syringe system accomodating seperate prefilled barrels for two constituents
ES2170853T3 (es) * 1995-03-28 2002-08-16 Fidia Advanced Biopolymers Srl Nanosferas que comprenden un polisacarido biocompatible.
US5779668A (en) 1995-03-29 1998-07-14 Abbott Laboratories Syringe barrel for lyophilization, reconstitution and administration
US6428771B1 (en) 1995-05-15 2002-08-06 Pharmaceutical Discovery Corporation Method for drug delivery to the pulmonary system
US6312407B1 (en) 1995-06-05 2001-11-06 Medtronic Percusurge, Inc. Occlusion of a vessel
US6214331B1 (en) * 1995-06-06 2001-04-10 C. R. Bard, Inc. Process for the preparation of aqueous dispersions of particles of water-soluble polymers and the particles obtained
US5766147A (en) 1995-06-07 1998-06-16 Winfield Medical Vial adaptor for a liquid delivery device
US5657756A (en) 1995-06-07 1997-08-19 Ctf Systems Inc. Method and systems for obtaining higher order gradiometer measurements with lower order gradiometers
US6143211A (en) 1995-07-21 2000-11-07 Brown University Foundation Process for preparing microparticles through phase inversion phenomena
US5877224A (en) * 1995-07-28 1999-03-02 Rutgers, The State University Of New Jersey Polymeric drug formulations
US6096344A (en) 1995-07-28 2000-08-01 Advanced Polymer Systems, Inc. Bioerodible porous compositions
US5840387A (en) 1995-07-28 1998-11-24 Aegis Biosciences L.L.C. Sulfonated multiblock copolymer and uses therefor
US5558822A (en) 1995-08-16 1996-09-24 Gas Research Institute Method for production of spheroidized particles
US5888546A (en) * 1995-08-28 1999-03-30 The Regents Of The University Of California Embolic material for endovascular occlusion of abnormal vasculature and method for using the same
US5833361A (en) 1995-09-07 1998-11-10 Funk; James E. Apparatus for the production of small spherical granules
CA2161863A1 (en) 1995-10-31 1997-05-01 Michael Vivian Sefton Angiogenic material and uses thereof
JPH09165328A (ja) * 1995-12-15 1997-06-24 Noboru Harada 小球体及びそれを含有する医薬用組成物
US5752974A (en) 1995-12-18 1998-05-19 Collagen Corporation Injectable or implantable biomaterials for filling or blocking lumens and voids of the body
EP0928182B1 (de) 1996-01-11 2002-05-08 Duoject Medical Systems Inc Abgabesystem für in pharmazeutischen phiolen verpackte arzneimittel
US5702361A (en) * 1996-01-31 1997-12-30 Micro Therapeutics, Inc. Method for embolizing blood vessels
US5895398A (en) 1996-02-02 1999-04-20 The Regents Of The University Of California Method of using a clot capture coil
US6051247A (en) * 1996-05-30 2000-04-18 University Of Florida Research Foundation, Inc. Moldable bioactive compositions
US5855615A (en) * 1996-06-07 1999-01-05 Menlo Care, Inc. Controller expansion sphincter augmentation media
US5792478A (en) 1996-07-08 1998-08-11 Advanced Uro Science Tissue injectable composition and method of use
US5695480A (en) * 1996-07-29 1997-12-09 Micro Therapeutics, Inc. Embolizing compositions
US5741331A (en) * 1996-07-29 1998-04-21 Corvita Corporation Biostable elastomeric polymers having quaternary carbons
US5830178A (en) 1996-10-11 1998-11-03 Micro Therapeutics, Inc. Methods for embolizing vascular sites with an emboilizing composition comprising dimethylsulfoxide
DE69729569T2 (de) * 1996-07-29 2005-06-23 Micro Therapeutics, Inc., San Clemente Kit aus drei glasfläschen zur vaskulären embolisierung unter verwendung eines dimethylsulfoxyd enthaltenden mittels
TW421658B (en) 1996-07-31 2001-02-11 Kanebo Ltd Porious spherical particles and the preparation process for preparing thereof
US5823198A (en) 1996-07-31 1998-10-20 Micro Therapeutics, Inc. Method and apparatus for intravasculer embolization
US5813411A (en) 1996-08-20 1998-09-29 Menlo Care, Inc. Method of deforming tissue with a swollen hydrogel
US5902832A (en) 1996-08-20 1999-05-11 Menlo Care, Inc. Method of synthesizing swollen hydrogel for sphincter augmentation
US5964797A (en) * 1996-08-30 1999-10-12 Target Therapeutics, Inc. Electrolytically deployable braided vaso-occlusion device
US5785642A (en) 1996-10-18 1998-07-28 Micro Therapeutics, Inc. Methods for treating urinary incontinence in mammals
US5756127A (en) 1996-10-29 1998-05-26 Wright Medical Technology, Inc. Implantable bioresorbable string of calcium sulfate beads
JPH10127754A (ja) * 1996-11-06 1998-05-19 Koken Co Ltd コラーゲンからなる塞栓材
JP3635316B2 (ja) * 1996-11-25 2005-04-06 株式会社アドバンス 球状セラミックス多孔体の製造方法
US6139963A (en) 1996-11-28 2000-10-31 Kuraray Co., Ltd. Polyvinyl alcohol hydrogel and process for producing the same
DE29724255U1 (de) 1996-12-18 2000-10-05 Alpha Bioverfahrenstechnik Gmb Mikrokapseln
US6090800A (en) * 1997-05-06 2000-07-18 Imarx Pharmaceutical Corp. Lipid soluble steroid prodrugs
WO1998045191A1 (en) 1997-04-10 1998-10-15 Johns Hopkins University Gaz syringe and package therefor
JP4102459B2 (ja) 1997-05-14 2008-06-18 森下仁丹株式会社 生体高分子を合成するシームレスカプセルおよびその製造方法
US6056844A (en) 1997-06-06 2000-05-02 Triton Systems, Inc. Temperature-controlled induction heating of polymeric materials
JPH10337335A (ja) * 1997-06-06 1998-12-22 Nippon Electric Glass Co Ltd 温熱治療用インプラント材
WO1998056435A1 (en) * 1997-06-13 1998-12-17 Micro Therapeutics, Inc. Contoured syringe and novel luer hub and methods for embolizing blood vessels
US6048908A (en) 1997-06-27 2000-04-11 Biopore Corporation Hydrophilic polymeric material
US5959073A (en) 1997-07-07 1999-09-28 Southwest Research Institute Method for preparing polymeric beads
JP2933580B2 (ja) * 1997-07-22 1999-08-16 鐘紡株式会社 スポンジ状球状粒子およびその製造方法
US6056721A (en) 1997-08-08 2000-05-02 Sunscope International, Inc. Balloon catheter and method
AU8913998A (en) 1997-08-28 1999-03-22 Boston Scientific Corporation System for implanting a cross-linked polysaccharide fiber and methods of formingand inserting the fiber
US6638621B2 (en) * 2000-08-16 2003-10-28 Lyotropic Therapeutics, Inc. Coated particles, methods of making and using
US6476069B2 (en) 1997-09-11 2002-11-05 Provasis Therapeutics Inc. Compositions for creating embolic agents and uses thereof
US6538026B1 (en) 1997-09-11 2003-03-25 Provasis Therapeutics, Inc. Compositions useful for remodeling body spaces
WO1999023954A1 (en) 1997-11-07 1999-05-20 Salviac Limited Implantable occluder devices for medical use
US5951160A (en) 1997-11-20 1999-09-14 Biomet, Inc. Method and apparatus for packaging, mixing and delivering bone cement
DE19752585B4 (de) 1997-11-27 2007-06-28 Inotech Ag Vorrichtung und Verfahren zum Verkapseln von mikrobiellen, pflanzlichen und tierischen Zellen bzw. von biologischen und chemischen Substanzen
US5989237A (en) 1997-12-04 1999-11-23 Baxter International Inc. Sliding reconstitution device with seal
WO1999042147A1 (en) 1998-02-23 1999-08-26 Massachusetts Institute Of Technology Biodegradable shape memory polymers
ES2265186T3 (es) 1998-02-23 2007-02-01 Mnemoscience Gmbh Polimeros con memoria de forma.
US6003566A (en) 1998-02-26 1999-12-21 Becton Dickinson And Company Vial transferset and method
US6059766A (en) 1998-02-27 2000-05-09 Micro Therapeutics, Inc. Gynecologic embolotherapy methods
AU2617099A (en) 1998-03-07 1999-09-20 Inotech Ag Method and device for capsulating microbial, plant and animal cells or biological and chemical substances
AU4067999A (en) 1998-04-03 1999-10-25 Du Pont Pharmaceuticals Company Inorganic material for radioactive drug delivery
US6047861A (en) * 1998-04-15 2000-04-11 Vir Engineering, Inc. Two component fluid dispenser
US6224794B1 (en) 1998-05-06 2001-05-01 Angiotech Pharmaceuticals, Inc. Methods for microsphere production
WO1999062079A1 (en) * 1998-05-26 1999-12-02 Bar-Ilan University Nucleation and growth of magnetic metal oxide nanoparticles and its use
US6224630B1 (en) * 1998-05-29 2001-05-01 Advanced Bio Surfaces, Inc. Implantable tissue repair device
EP1082072B8 (de) 1998-06-04 2014-03-05 New York University Endovaskuläre dünnfilmvorrichtungen zur behandlung und vorbeugung des schlaganfalls
US6267154B1 (en) 1998-06-05 2001-07-31 Abbott Laboratories System for storing mixing and administering a drug
US6165193A (en) 1998-07-06 2000-12-26 Microvention, Inc. Vascular embolization with an expansible implant
US6264861B1 (en) 1998-08-05 2001-07-24 Xeikon Nv Method for producing rounded polymeric particles
US6315709B1 (en) * 1998-08-07 2001-11-13 Stereotaxis, Inc. Magnetic vascular defect treatment system
US6152943A (en) * 1998-08-14 2000-11-28 Incept Llc Methods and apparatus for intraluminal deposition of hydrogels
CA2248592A1 (en) 1998-08-31 2000-02-29 Christopher D. Batich Microspheres for use in the treatment of cancer
US6296622B1 (en) 1998-12-21 2001-10-02 Micrus Corporation Endoluminal device delivery system using axially recovering shape memory material
FR2784580B1 (fr) * 1998-10-16 2004-06-25 Biosepra Inc Microspheres de polyvinyl-alcool et procedes de fabrication de celles-ci
US6238335B1 (en) 1998-12-11 2001-05-29 Enteric Medical Technologies, Inc. Method for treating gastroesophageal reflux disease and apparatus for use therewith
JP2000189511A (ja) 1998-12-25 2000-07-11 Kaneka Medeikkusu:Kk 塞栓形成材料
US6162377A (en) 1999-02-23 2000-12-19 Alberta Research Council Inc. Apparatus and method for the formation of uniform spherical particles
US6495161B1 (en) 1999-03-09 2002-12-17 Vivorx, Inc. Cytoprotective biocompatible containment systems for biologically active materials and methods of making same
US6296604B1 (en) * 1999-03-17 2001-10-02 Stereotaxis, Inc. Methods of and compositions for treating vascular defects
US6306425B1 (en) 1999-04-09 2001-10-23 Southern Research Institute Injectable naltrexone microsphere compositions and their use in reducing consumption of heroin and alcohol
US6368658B1 (en) * 1999-04-19 2002-04-09 Scimed Life Systems, Inc. Coating medical devices using air suspension
US6280457B1 (en) 1999-06-04 2001-08-28 Scimed Life Systems, Inc. Polymer covered vaso-occlusive devices and methods of producing such devices
CZ2002728A3 (cs) 1999-08-27 2002-08-14 Southern Research Institute Prostředek ve formě mikročástic obsahující buprenorfin, léková forma a pouľití
FR2797769B1 (fr) 1999-09-01 2003-07-25 Cis Bio Int Produits radiopharmaceutiques et leur procede de preparation
JP2001079011A (ja) 1999-09-14 2001-03-27 Akira Morimoto 血管塞栓コイルとその製造方法
US6277392B1 (en) 1999-09-16 2001-08-21 Carbon Medical Technologies, Inc. Tissue injectable composition
US6602261B2 (en) 1999-10-04 2003-08-05 Microvention, Inc. Filamentous embolic device with expansile elements
US6238403B1 (en) 1999-10-04 2001-05-29 Microvention, Inc. Filamentous embolic device with expansible elements
KR100335866B1 (ko) * 2000-01-06 2002-05-10 박호군 폴리아세트산비닐 코어/폴리비닐알코올 외피의 2중 구조를갖는 미세구형 색전재료 및 그의 제조방법
US6306419B1 (en) 2000-02-23 2001-10-23 Aegis Biosciences, Llc Medical uses of styrene sulfonate polymers
DE60139112D1 (de) * 2000-03-06 2009-08-13 Boston Scient Ltd Unter ultralschall sichtbare embolisierende substanzen
US6652883B2 (en) * 2000-03-13 2003-11-25 Biocure, Inc. Tissue bulking and coating compositions
ATE373682T1 (de) 2000-03-13 2007-10-15 Biocure Inc Embolische zusammensetzungen
US6423332B1 (en) 2000-05-26 2002-07-23 Ethicon, Inc. Method and composition for deforming soft tissues
DE10026620A1 (de) 2000-05-29 2002-03-07 Gerhard Quelle Poröse Implantate und Partikel
US6486822B1 (en) * 2000-06-07 2002-11-26 The Boeing Company Chemically modified radar absorbing materials and an associated fabrication method
US6355275B1 (en) * 2000-06-23 2002-03-12 Carbon Medical Technologies, Inc. Embolization using carbon coated microparticles
JP2002017848A (ja) 2000-07-12 2002-01-22 Terumo Corp 生体内注入可能な微粒子およびその製造法
WO2002011696A2 (en) * 2000-08-08 2002-02-14 Ev & M Active tissue augmentation materials and method
JP2004505761A (ja) 2000-08-15 2004-02-26 ボード・オブ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・イリノイ 微小粒子
US6394965B1 (en) 2000-08-15 2002-05-28 Carbon Medical Technologies, Inc. Tissue marking using biocompatible microparticles
US6703127B2 (en) 2000-09-27 2004-03-09 Microtek Laboratories, Inc. Macrocapsules containing microencapsulated phase change materials
AUPR098200A0 (en) 2000-10-25 2000-11-16 Sirtex Medical Limited Production of low density radionuclide containing microspheres
AUPR098300A0 (en) * 2000-10-25 2000-11-16 Sirtex Medical Limited Polymer based radionuclide containing microspheres
US6545097B2 (en) 2000-12-12 2003-04-08 Scimed Life Systems, Inc. Drug delivery compositions and medical devices containing block copolymer
WO2003053325A2 (en) 2000-12-13 2003-07-03 Purdue Research Foundation Microencapsulation of drugs by solvent exchange
US6632531B2 (en) 2001-02-15 2003-10-14 Rohm And Haas Company Porous particles, their aqueous dispersions, and method of preparation
US6887857B2 (en) 2001-04-27 2005-05-03 Scimed Life Systems, Inc. Microparticle protection of therapeutic agents
US6997863B2 (en) * 2001-07-25 2006-02-14 Triton Biosystems, Inc. Thermotherapy via targeted delivery of nanoscale magnetic particles
US20030032935A1 (en) * 2001-08-10 2003-02-13 Scimed Life Systems, Inc. Packages facilitating convenient mixing and delivery of liquids
US7094369B2 (en) 2002-03-29 2006-08-22 Scimed Life Systems, Inc. Processes for manufacturing polymeric microspheres
EP1490119A1 (de) * 2002-03-29 2004-12-29 Boston Scientific Limited Gewebebehandlung
US7131997B2 (en) * 2002-03-29 2006-11-07 Scimed Life Systems, Inc. Tissue treatment
US7462366B2 (en) 2002-03-29 2008-12-09 Boston Scientific Scimed, Inc. Drug delivery particle
US7218962B2 (en) 2002-03-29 2007-05-15 Boston Scientific Scimed, Inc. Magnetically enhanced injection catheter
US7008979B2 (en) * 2002-04-30 2006-03-07 Hydromer, Inc. Coating composition for multiple hydrophilic applications
US7838699B2 (en) 2002-05-08 2010-11-23 Biosphere Medical Embolization using degradable crosslinked hydrogels
US7449236B2 (en) 2002-08-09 2008-11-11 Boston Scientific Scimed, Inc. Porous polymeric particle comprising polyvinyl alcohol and having interior to surface porosity-gradient
US20040076582A1 (en) 2002-08-30 2004-04-22 Dimatteo Kristian Agent delivery particle
WO2004014446A1 (en) * 2002-08-09 2004-02-19 Boston Scientific Limited Embolization
US8012454B2 (en) 2002-08-30 2011-09-06 Boston Scientific Scimed, Inc. Embolization
US7883490B2 (en) 2002-10-23 2011-02-08 Boston Scientific Scimed, Inc. Mixing and delivery of therapeutic compositions
US7588825B2 (en) 2002-10-23 2009-09-15 Boston Scientific Scimed, Inc. Embolic compositions
US7792568B2 (en) 2003-03-17 2010-09-07 Boston Scientific Scimed, Inc. MRI-visible medical devices
US7906148B2 (en) * 2003-07-31 2011-03-15 Boston Scientific Scimed, Inc. Latex medical articles for release of antimicrobial agents
US20050037047A1 (en) * 2003-08-11 2005-02-17 Young-Ho Song Medical devices comprising spray dried microparticles

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