DE60120660D1 - Zusammensetzungen von vernetzbaren prepolymeren für bioabbaubare implantate - Google Patents
Zusammensetzungen von vernetzbaren prepolymeren für bioabbaubare implantateInfo
- Publication number
- DE60120660D1 DE60120660D1 DE60120660T DE60120660T DE60120660D1 DE 60120660 D1 DE60120660 D1 DE 60120660D1 DE 60120660 T DE60120660 T DE 60120660T DE 60120660 T DE60120660 T DE 60120660T DE 60120660 D1 DE60120660 D1 DE 60120660D1
- Authority
- DE
- Germany
- Prior art keywords
- prepolymers
- composition
- bioabcable
- implants
- networked
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
- C08F290/08—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated side groups
- C08F290/14—Polymers provided for in subclass C08G
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/91—Polymers modified by chemical after-treatment
- C08G63/912—Polymers modified by chemical after-treatment derived from hydroxycarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/602—Type of release, e.g. controlled, sustained, slow
- A61L2300/604—Biodegradation
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP00201198A EP1142596A1 (de) | 2000-04-03 | 2000-04-03 | Zusammensetzung von vernetzbaren Prepolymeren zum Gebrauch in therapeutisch aktiven, bioabbaubaren Implantaten |
EP00201198 | 2000-04-03 | ||
PCT/EP2001/003766 WO2001074411A1 (en) | 2000-04-03 | 2001-04-03 | Compositions of crosslinkable prepolymers for biodegradable implants |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60120660D1 true DE60120660D1 (de) | 2006-07-27 |
DE60120660T2 DE60120660T2 (de) | 2007-06-14 |
Family
ID=8171297
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60120660T Expired - Lifetime DE60120660T2 (de) | 2000-04-03 | 2001-04-03 | Zusammensetzungen von vernetzbaren prepolymeren für bioabbaubare implantate |
Country Status (7)
Country | Link |
---|---|
US (1) | US6933328B2 (de) |
EP (2) | EP1142596A1 (de) |
AT (1) | ATE329630T1 (de) |
AU (2) | AU2001262159B2 (de) |
CA (1) | CA2404683C (de) |
DE (1) | DE60120660T2 (de) |
WO (1) | WO2001074411A1 (de) |
Families Citing this family (73)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6786915B2 (en) * | 2000-04-19 | 2004-09-07 | Radi Medical Systems Ab | Reinforced absorbable medical sealing device |
AU2001288829A1 (en) * | 2000-09-06 | 2002-03-22 | Ap Pharma, Inc. | Degradable polyacetal polymers |
ATE316105T1 (de) * | 2000-11-20 | 2006-02-15 | Matrix Innovation Inc | Herstellung amphiphiler fester träger für die peptidsynthese und die bioorganische und organische chemie |
EP1341484B1 (de) * | 2000-12-08 | 2009-05-06 | Osteotech, Inc. | Implantat für orthopädische anwendungen |
US6590059B2 (en) | 2001-05-11 | 2003-07-08 | Ap Pharma, Inc. | Bioerodible polyorthoesters from dioxolane-based diketene acetals |
US8740987B2 (en) * | 2001-06-04 | 2014-06-03 | Warsaw Orthopedic, Inc. | Tissue-derived mesh for orthopedic regeneration |
JP4624678B2 (ja) | 2002-02-21 | 2011-02-02 | パイオニア・サージカル・オーソバイオロジックス,インコーポレイテッド | 架橋生物活性ヒドロゲルマトリックス |
US20080086792A1 (en) | 2006-10-13 | 2008-04-17 | Thomas Charles Kuracina | Method and apparatus for diverting sweat, liquid, moisture or the like from an eye |
US20040127563A1 (en) * | 2002-03-22 | 2004-07-01 | Deslauriers Richard J. | Methods of performing medical procedures which promote bone growth, compositions which promote bone growth, and methods of making such compositions |
SG145565A1 (en) * | 2002-08-12 | 2008-09-29 | Osteotech Inc | Synthesis of a bone-polymer composite material |
CN101632843A (zh) * | 2002-08-20 | 2010-01-27 | 精密技术公司 | 骨生长诱导材料的携带和输送用组合物以及生产和应用该组合物的方法 |
WO2004032988A2 (en) * | 2002-10-08 | 2004-04-22 | Osteotech, Inc. | Coupling agents for orthopedic biomaterials |
US20040152800A1 (en) * | 2002-10-09 | 2004-08-05 | Shalaby Shalaby W. | Photo-crosslinkable, crystalline, polyaxial, absorbable polyester for rapid prototyping |
US7045589B2 (en) | 2002-11-15 | 2006-05-16 | A.P. Pharma, Inc. | Bioerodible poly(ortho esters) from dioxane-based di(ketene acetals), and block copolymers containing them |
EP1578957B1 (de) * | 2002-12-12 | 2015-04-15 | Warsaw Orthopedic, Inc. | Formbarer und einstellbarer polymer-knochenverbund und herstellungsverfahren dafür |
US20060052471A1 (en) * | 2003-02-27 | 2006-03-09 | A Enterprises, Inc. | Initiators and crosslinkable polymeric materials |
US7393493B2 (en) * | 2003-02-27 | 2008-07-01 | A Enterprises, Inc. | Crosslinkable polymeric materials and their applications |
DE10314082A1 (de) * | 2003-03-28 | 2004-10-21 | Mcs Micro Carrier Systems Gmbh | Biodegradierbares injizierbares Implantat |
US7067123B2 (en) | 2003-04-29 | 2006-06-27 | Musculoskeletal Transplant Foundation | Glue for cartilage repair |
US7901457B2 (en) | 2003-05-16 | 2011-03-08 | Musculoskeletal Transplant Foundation | Cartilage allograft plug |
CA2536041A1 (en) * | 2003-11-10 | 2005-05-26 | Angiotech International Ag | Medical implants and fibrosis-inducing agents |
US8012210B2 (en) | 2004-01-16 | 2011-09-06 | Warsaw Orthopedic, Inc. | Implant frames for use with settable materials and related methods of use |
JP2007519492A (ja) * | 2004-01-30 | 2007-07-19 | オステオテック,インコーポレイテッド | 脊椎融合のための積み重ねインプラント |
TW200533385A (en) * | 2004-03-03 | 2005-10-16 | Commw Scient Ind Res Org | Biocompatible polymer compositions for dual or multi staged curing |
EP1789088A4 (de) | 2004-03-24 | 2009-12-30 | Doctor S Res Group Inc | Verfahren zur durchführung von medizinischen verfahren zur förderung des knochenwachstums, verfahren zur herstellung von zusammensetzungen zur förderung des knochenwachstums und gerät zur verwendung bei solchen verfahren |
ATE462451T1 (de) * | 2004-06-16 | 2010-04-15 | Affinergy Inc | Grenzflächenbiomaterialien zur förderung der anhaftung von zielanalyten |
US7837740B2 (en) | 2007-01-24 | 2010-11-23 | Musculoskeletal Transplant Foundation | Two piece cancellous construct for cartilage repair |
FI122108B (fi) * | 2004-11-17 | 2011-08-31 | Jvs Polymers Oy | Silloittuva biopolymeeri |
WO2006088866A2 (en) * | 2005-02-14 | 2006-08-24 | Indiana University Research And Technology Corporation | Biodegradable load-bearing carrier for bone regeneration |
AT501700B1 (de) * | 2005-04-14 | 2011-03-15 | Univ Wien Tech | Mit strahlung härtbare, biologisch abbaubare zusammensetzungen und deren verwendung als stützmaterialien für den knochenersatz |
CA2611693A1 (en) * | 2005-06-15 | 2006-12-28 | Surmodics, Inc. | Macromer composition including light activated initiator |
US7815926B2 (en) | 2005-07-11 | 2010-10-19 | Musculoskeletal Transplant Foundation | Implant for articular cartilage repair |
WO2007048105A2 (en) * | 2005-10-19 | 2007-04-26 | A Enterprises, Inc. | Curable bone substitute |
CA2630661A1 (en) * | 2005-11-29 | 2007-06-07 | Indiana University Research And Technology Corporation | Biodegradable implant ploymers and composites |
CA2637606C (en) * | 2006-01-19 | 2013-03-19 | Osteotech, Inc. | Porous osteoimplant |
EP1976460A4 (de) | 2006-01-19 | 2012-06-20 | Warsaw Orthopedic Inc | Injizierbare und formbare knochenersatzmaterialien |
US20090311303A1 (en) * | 2006-04-27 | 2009-12-17 | Queensland University Of Technology | Biodegradable implants for bone fusion and compositions therefor |
EP2044142A2 (de) | 2006-06-29 | 2009-04-08 | Medtronic, Inc. | Poly(orthoester)polymere sowie herstellungs- und verwendungsverfahren dafür |
GB0618963D0 (en) * | 2006-09-26 | 2006-11-08 | Ucl Business Plc | Formulations and composites with reactive fillers |
US8435551B2 (en) | 2007-03-06 | 2013-05-07 | Musculoskeletal Transplant Foundation | Cancellous construct with support ring for repair of osteochondral defects |
AT506168B1 (de) * | 2007-11-23 | 2012-02-15 | Univ Wien Tech | Verwendung von zusammensetzungen zur herstellung biologisch abbaubarer, bioverträglicher, vernetzter polymere auf basis von polyvinylalkohol |
EP2219697A2 (de) * | 2007-11-23 | 2010-08-25 | Technische Universität Wien | Durch polymerisation härtbare zusammensetzung zur herstellung biologisch abbaubarer, bioverträglicher, vernetzter polymere auf basis von polyvinylalkohol |
CA2717725A1 (en) | 2008-03-05 | 2009-09-11 | Musculoskeletal Transplant Foundation | Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles |
US9068065B2 (en) | 2008-04-14 | 2015-06-30 | Basf Se | Hydrolytically decomposable ionic copolymers |
DE102008018905A1 (de) | 2008-04-14 | 2009-10-15 | Philipps-Universität Marburg | Hydrolytisch abbaubare ionische Copolymerisate |
DE102008028146A1 (de) | 2008-06-14 | 2009-12-17 | Philipps-Universität Marburg | Neue hydrolytisch abbaubare ionische Copolymerisate |
US8956642B2 (en) | 2008-04-18 | 2015-02-17 | Medtronic, Inc. | Bupivacaine formulation in a polyorthoester carrier |
US8475823B2 (en) | 2008-04-18 | 2013-07-02 | Medtronic, Inc. | Baclofen formulation in a polyorthoester carrier |
WO2009152276A2 (en) | 2008-06-10 | 2009-12-17 | University Of North Carolina At Charlotte | Photoacid generators and lithographic resists comprising the same |
WO2011025650A1 (en) * | 2009-08-25 | 2011-03-03 | Genzyme Corporation | Cartilage repair |
US8829069B2 (en) | 2010-05-26 | 2014-09-09 | Medisse B.V. | Method for preparing a degradable polymer network |
US20120101593A1 (en) | 2010-10-20 | 2012-04-26 | BIOS2 Medical, Inc. | Implantable polymer for bone and vascular lesions |
US10525168B2 (en) | 2010-10-20 | 2020-01-07 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications |
US11484627B2 (en) | 2010-10-20 | 2022-11-01 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications |
US10525169B2 (en) | 2010-10-20 | 2020-01-07 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications |
US11207109B2 (en) | 2010-10-20 | 2021-12-28 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications |
US11058796B2 (en) | 2010-10-20 | 2021-07-13 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications |
US11291483B2 (en) | 2010-10-20 | 2022-04-05 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants |
CN102120817A (zh) * | 2011-01-11 | 2011-07-13 | 同济大学 | 一种交联型聚乳酸及其制备方法 |
US20120219629A1 (en) * | 2011-02-25 | 2012-08-30 | Empire Technology Development Llc | Compositions and methods for controlled delivery of compounds |
WO2013067195A1 (en) | 2011-11-02 | 2013-05-10 | Halscion, Inc. | Methods and compositions for wound treatment |
WO2013130877A1 (en) | 2012-02-29 | 2013-09-06 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, including the use of composite implants |
EP3269335B1 (de) | 2012-10-02 | 2019-03-06 | McCullen, Seth | Implantierbare vorrichtungen für muskuloskelettäre reparatur und regeneration |
US9951178B2 (en) * | 2012-10-09 | 2018-04-24 | Shanghai Micoport Medical (Group) Co., Ltd. | Biodegradable cross-linked polymer, vascular stent and manufacturing methods therefor |
EP3795635A1 (de) | 2013-05-23 | 2021-03-24 | 206 ORTHO, Inc. | Vorrichtung zur behandlung von knochenbrüchen und/oder zur stärkung und/oder vermehrung von knochen einschliesslich der bereitstellung und verwendung zusammengesetzter implantate |
WO2016054463A1 (en) | 2014-10-02 | 2016-04-07 | Mccullen Seth | Anatomically designed meniscus implantable devices |
CN105818492B (zh) * | 2016-03-29 | 2018-02-16 | 中材科技股份有限公司 | 一种生物活性磷酸盐基连续玻璃纤维纺织复合材料及其用途 |
WO2018204440A2 (en) | 2017-05-02 | 2018-11-08 | Mccullen Seth | Composite joint implant |
US11331854B2 (en) * | 2018-03-26 | 2022-05-17 | Arevo, Inc. | System and method for dispensing composite filaments for additive manufacturing |
WO2020150332A1 (en) * | 2019-01-15 | 2020-07-23 | University Of Massachusetts | Eggshell particle containing hydrogels and prepolymer compositions for biomedical applications |
GB201910895D0 (en) * | 2019-07-31 | 2019-09-11 | Univ Birmingham | Curable monomers and compositions |
CN111067670B (zh) * | 2019-12-24 | 2022-10-14 | 北京壹点灵动科技有限公司 | 髋臼骨缺损的评估方法及装置、电子设备 |
JP2021191810A (ja) * | 2020-06-05 | 2021-12-16 | 日清紡ホールディングス株式会社 | 海洋生分解促進剤 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5085861A (en) * | 1987-03-12 | 1992-02-04 | The Beth Israel Hospital Association | Bioerodable implant composition comprising crosslinked biodegradable polyesters |
US4938763B1 (en) * | 1988-10-03 | 1995-07-04 | Atrix Lab Inc | Biodegradable in-situ forming implants and method of producing the same |
US5108755A (en) * | 1989-04-27 | 1992-04-28 | Sri International | Biodegradable composites for internal medical use |
US5410016A (en) * | 1990-10-15 | 1995-04-25 | Board Of Regents, The University Of Texas System | Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers |
DE69530919T2 (de) * | 1994-04-08 | 2004-05-13 | Atrix Laboratories, Inc., Fort Collins | Beigeordnetes polymersystem zur verwendung mit einer medizinischen vorrichtung |
US5900245A (en) * | 1996-03-22 | 1999-05-04 | Focal, Inc. | Compliant tissue sealants |
US5703200A (en) * | 1996-03-15 | 1997-12-30 | Ethicon, Inc. | Absorbable copolymers and blends of 6,6-dialkyl-1,4-dioxepan-2-one and its cyclic dimer |
ZA978537B (en) * | 1996-09-23 | 1998-05-12 | Focal Inc | Polymerizable biodegradable polymers including carbonate or dioxanone linkages. |
US5837752A (en) * | 1997-07-17 | 1998-11-17 | Massachusetts Institute Of Technology | Semi-interpenetrating polymer networks |
DE69920198T2 (de) * | 1998-04-13 | 2005-09-22 | Massachusetts Institute Of Technology, Cambridge | Kamm-polymere zur regelung der zelloberflächenwechselwirkung |
US6171610B1 (en) * | 1998-04-24 | 2001-01-09 | University Of Massachusetts | Guided development and support of hydrogel-cell compositions |
MXPA01007777A (es) | 1999-02-01 | 2003-10-06 | Eidgenoess Tech Hochschule | Bio-materiales formadas por reaccion de adicion nucleofila a grupos insaturados conjugados. |
CA2410637C (en) | 2000-05-31 | 2007-04-10 | Mnemoscience Gmbh | Shape memory polymers seeded with dissociated cells for tissue engineering |
-
2000
- 2000-04-03 EP EP00201198A patent/EP1142596A1/de not_active Withdrawn
-
2001
- 2001-04-03 AT AT01936174T patent/ATE329630T1/de not_active IP Right Cessation
- 2001-04-03 AU AU2001262159A patent/AU2001262159B2/en not_active Ceased
- 2001-04-03 DE DE60120660T patent/DE60120660T2/de not_active Expired - Lifetime
- 2001-04-03 US US10/239,623 patent/US6933328B2/en not_active Expired - Fee Related
- 2001-04-03 CA CA2404683A patent/CA2404683C/en not_active Expired - Fee Related
- 2001-04-03 WO PCT/EP2001/003766 patent/WO2001074411A1/en active IP Right Grant
- 2001-04-03 EP EP01936174A patent/EP1267953B1/de not_active Expired - Lifetime
- 2001-04-03 AU AU6215901A patent/AU6215901A/xx active Pending
Also Published As
Publication number | Publication date |
---|---|
AU2001262159B2 (en) | 2005-07-14 |
EP1267953A1 (de) | 2003-01-02 |
WO2001074411A1 (en) | 2001-10-11 |
US6933328B2 (en) | 2005-08-23 |
EP1267953B1 (de) | 2006-06-14 |
EP1142596A1 (de) | 2001-10-10 |
CA2404683A1 (en) | 2001-10-11 |
ATE329630T1 (de) | 2006-07-15 |
AU6215901A (en) | 2001-10-15 |
DE60120660T2 (de) | 2007-06-14 |
US20030114552A1 (en) | 2003-06-19 |
CA2404683C (en) | 2011-02-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |