DE10049812B4 - Device for filtering out macroscopic particles from the bloodstream during local removal of an aortic valve on the human or animal heart - Google Patents
Device for filtering out macroscopic particles from the bloodstream during local removal of an aortic valve on the human or animal heart Download PDFInfo
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- DE10049812B4 DE10049812B4 DE10049812A DE10049812A DE10049812B4 DE 10049812 B4 DE10049812 B4 DE 10049812B4 DE 10049812 A DE10049812 A DE 10049812A DE 10049812 A DE10049812 A DE 10049812A DE 10049812 B4 DE10049812 B4 DE 10049812B4
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- Prior art keywords
- filter screens
- filter
- filter screen
- aortic valve
- screens
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B17/221—Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/01—Filters implantable into blood vessels
- A61F2/0103—With centering means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/01—Filters implantable into blood vessels
- A61F2/0105—Open ended, i.e. legs gathered only at one side
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/01—Filters implantable into blood vessels
- A61F2/012—Multiple filtering units
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/01—Filters implantable into blood vessels
- A61F2002/018—Filters implantable into blood vessels made from tubes or sheets of material, e.g. by etching or laser-cutting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
- A61F2230/0004—Rounded shapes, e.g. with rounded corners
- A61F2230/0006—Rounded shapes, e.g. with rounded corners circular
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0063—Three-dimensional shapes
- A61F2230/0069—Three-dimensional shapes cylindrical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0063—Three-dimensional shapes
- A61F2230/0073—Quadric-shaped
- A61F2230/0076—Quadric-shaped ellipsoidal or ovoid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0063—Three-dimensional shapes
- A61F2230/0073—Quadric-shaped
- A61F2230/008—Quadric-shaped paraboloidal
Abstract
Vorrichtung zum Ausfiltern makroskopischer Teilchen aus einer Blutbahn beim lokalen Abtrag einer Aortenklappe am menschlichen oder tierischen Herz mit wenigstens einem schirmartig aufspannbaren Filterschirm, der aus einem zusammengefalteten Zustand in einen aufgespannten Zustand aufspannbar ist und mittels eines Arbeitskatheters betätigbar ist, dadurch gekennzeichnet, dass zwei Filterschirme vorgesehen sind, die derart in Wirkverbindung stehen, dass im aufgespannten Zustand ihre konkav ausgebildeten Seiten gegenüberliegen.Device for filtering out macroscopic particles from a bloodstream during the local ablation of an aortic valve on the human or animal heart with at least one filter screen that can be stretched out like an umbrella, which can be stretched out from a folded state into a stretched out state and can be actuated by means of a working catheter, characterized in that two filter screens are provided are in operative connection in such a way that their concave sides are opposite in the open state.
Description
Die Erfindung bezieht sich auf eine Vorrichtung zum Ausfiltern makroskopischer Teilchen aus einer Blutbahn beim lokalen Abtrag einer Aortenklappe am menschlichen oder tierischen Herz mit wenigstens einem schirmartig aufspannbaren Filterschirm, der aus einem zusammengefalteten Zustand in einen aufgespannten Zustand aufspannbar ist und mittels eines Arbeitskatheters betätigbar ist.The invention relates to a Device for filtering macroscopic particles from a bloodstream when removing an aortic valve locally on human or animal Heart with at least one screen-like filter screen that from a folded state to a stretched state can be clamped and actuated by means of a working catheter.
Stand der TechnikState of the art
Bei einer Vielzahl von Patienten kommt es vor, dass sich im Laufe der Zeit Ablagerungen an der Herzklappe bilden, insbesondere an der Aortenklappe, häufig in Form von Kalkablagerungen oder sonstigen Materialdepositionen. Durch derartige Materialablagerungen an der Aortenklappe, die in einem gesunden Zustand als ein feines flexibles Gewebesegel ausgebildet ist, kommt es zu einer irreversiblen Versteifung der Aortenklappe, wodurch insbesondere der Blutabfluss aus dem Herz erheblich in Mitleidenschaft gezogen wird. Blutunterversorgung im gesamten Körper ist die Folge, so dass in einem derart fortgeschrittenen Stadium ein akuter Handlungsbedarf besteht, will man schwerwiegende Folgen für den Patienten vermeiden. Bisher bekannte medikamentöse Behandlungsmethoden zeigen jedoch nur begrenzten Erfolg, so dass nach heutiger Kenntnis einer Verkalkung von Aortenklappen lediglich durch einen schwerwiegende chirurgischen Eingriff begegnet werden kann.In a large number of patients there may be deposits on the heart valve over time form, especially on the aortic valve, often in the form of limescale or other material deposition. Through such material deposits on the aortic valve, which is in a healthy state as a fine flexible fabric sail is formed, there is an irreversible Stiffening of the aortic valve, which in particular causes blood drainage is severely affected from the heart. Blood shortage in the whole body is the result, so at such an advanced stage there is an acute need for action if one wants serious consequences for the Avoid patients. Show previously known drug treatment methods However, only limited success, so that, according to today's knowledge, Calcification of aortic valves only by a serious one surgical intervention can be countered.
Üblicherweise
wird in diesem Fall im Rahmen einer Sternotomie der Brustkorb eines
Menschen geöffnet
um Zugang zum Herz und insbesondere zu den verkalkten Aortenklappen
zu erhalten, die mit bekannten Schneidewerkzeugen aus dem Körper extrahiert
wird. Beispielsweise eignen sich hierzu Extraktionswerkzeuge wie
sie in den amerikanischen Druckschriften
Nun sind auch Operationstechniken bekannt geworden, die unter Einsatz von Kathetern und Endoskopen eine Behandlung der Aortenklappe auch mit weit geringeren Belastungen für den Patienten ermöglichen. Dies jedoch setzt voraus, dass die verkalkte Aortenklappe mit Hilfe geeigneter Katheterwerkzeuge vor Ort abgetragen wird. Ein derartiger Abtrag der verkalkten Aortenklappe, unabhängig davon mit welchen Abtragungstechniken gearbeitet wird, führt jedoch nahezu unvermeidbar zu zerkleinerten, abgetragenen, d.h. abgetrennten und Iosgelösten Gewebebruchstücken, die in die freie Blutbahn gelangen können, sofern sie nicht durch entsprechende Absaugtechniken extrakorporal extrahiert werden können. Derartige, sich in der Blutbahn befindliche Bruchstücke mit makroskopischen Teilchendurchmessern von > 7,5 μm erhöhen jedoch drastisch die Thrombose- und Emboliegefahr des Patienten, so dass nach Maßnahmen gesucht wird, eben jene, bei der Extraktion der verkalkten Aortenklappe möglicherweise entstehenden Abbruchstücke vollständig aus der Blutbahn zu entfernen.Now there are also surgical techniques become known using catheters and endoscopes treatment of the aortic valve even with far lower loads for the Enable patients. However, this presupposes that the calcified aortic valve with the help suitable catheter tools is removed on site. Such a deduction the calcified aortic valve, regardless of which ablation techniques is worked, leads however almost inevitably to shredded, worn, i.e. separated and loosened Tissue fragments, that can get into the free bloodstream if they cannot get through appropriate suction techniques can be extracted extracorporeally. such, fragments in the bloodstream with macroscopic particle diameters of> 7.5 μm, however, increase drastically the risk of thrombosis and embolism of the patient, so that after measures that is, the extraction of the calcified aortic valve may be sought resulting demolition pieces Completely to remove from the bloodstream.
Aus der
Darstellung der ErfindungPresentation of the invention
Der Erfindung liegt die Aufgabe zugrunde, eine Vorrichtung zum Ausfiltern bzw. Auffangen makroskopischer Teilchen aus einer Blutbahn für den lokalen Abtrag einer Aortenklappe am menschlichen oder tierischen Herz mit wenigstens einem schirmartig aufspannbaren Filterschirm, der aus einem zusammengefalteten Zustand in einen aufgespannten Zustand aufspannbar ist und mittels eines Arbeitskatheters betätigbar ist, derart weiterzubilden, dass während des chirurgischen Eingriffes zum Abtrag der Aortenklappe entstehende makroskopisch große Teilchen, die nicht entsprechend entsorgt werden und in die Blutbahn gelangen, vollständig aufgefangen werden sollen. Es soll insbesondere erreicht werden, dass der chirurgische Eingriff zur Ablation der Aortenklappe sicherer durchführbar ist. Insbesondere soll die Vorrichtung auch einen minimal invasiven Eingriff zur Ablation der Aortenklappe nicht hinderlich im Wege stehen, sondern überdies den Eingriff erleichtern.The invention has for its object a Device for filtering or collecting macroscopic particles from a bloodstream for the local removal of an aortic valve on the human or animal Heart with at least one screen-like filter screen, the from a folded state to a stretched state can be clamped and actuated by means of a working catheter, to train in such a way that during surgical intervention to remove the aortic valve macroscopically large particles, that are not properly disposed of and enter the bloodstream, Completely should be caught. In particular, that surgery to abort the aortic valve is safer feasible is. In particular, the device should also have a minimally invasive procedure are not a hindrance to ablation of the aortic valve, but moreover make the intervention easier.
Die Lösung der Aufgabe ist im Anspruch 1 angegeben. Vorteilhafte Weiterbildungen des Erfindungsgedankens sind Gegenstand der Unteransprüche sowie dem Beschreibungstext unter Bezugnahme auf das Ausführungsbeispiel zu entnehmen.The solution to the problem is in the claim 1 specified. Advantageous further developments of the inventive concept are the subject of the subclaims and the description text with reference to the embodiment refer to.
Erfindungsgemäß ist eine Vorrichtung zum Ausfiltern makroskopischer Teilchen aus einer Blutbahn beim lokalen Abtrag einer Aortenklappe, insbesondere am menschlichen Herz, gemäß dem Oberbegriff des Anspruchs 1 derart ausgebildet, dass zwei Filterschirme vorgesehen sind, die derart in Wirkverbindung stehen, dass im aufgespannten Zustand ihre konkav ausgebildeten Filterschirmseiten gegenüberliegen.According to the invention is a device for filtering macroscopic particles from a bloodstream during local ablation an aortic valve, especially on the human heart, according to the generic term of claim 1 designed such that two filter screens are provided are in operative connection in such a way that in the spanned Condition their concave filter screen sides are opposite.
Der Erfindung liegt die Idee zugrunde, dass durch die Kombination zweier Filterschirme, deren Konkavseiten sich gegenüberliegen, ein Volumen einbeschrieben wird, das in Art eines Käfigs von den Filterschirmen umgeben wird und in dem die chirurgischen Maßnahmen an der Aortenklappe durchgeführt werden kann. Hierzu ist es erforderlich, dass ein Filterschirm vor und der andere Filterschirm hinter der Aortenklappe angeordnet wird. Nach entsprechendem Aufspannen der Filterschirme kann innerhalb des durch die Filterschirme einbeschriebenen Volumens die Ablation der Aortenklappe vorgenommen werden. Während der Ablation entstehende makroskopische Bruchstücke werden von den Filterschirmflächen aufgefangen und daran gehindert, in die übrige Blutbahn zu gelangen. Nach Vollendung der Ablation und sonstiger chirurgischer Maßnahmen werden die Filterschirme zusammengefaltet und die darin gefangenen makroskopischen Teilchen wie auch evtl. die als Ganzes entfente Aortenklappe eingeschlossen. Die Dimensionierung der Filterschirmchen ist dabei derart gewählt, dass sie durch übliche Arbeitshohlkatheter geschoben werden können, so dass nach Beendigung der chirurgischen Maßnahme die mit makroskopischen Teilchen gefüllten Filterschirmchen durch einen entsprechenden Arbeitskanal extrakorporal verbracht werden können.The invention is based on the idea that the combination of two filter screens, the concave sides of which lie opposite one another, inscribes a volume which is surrounded by the filter screens in the manner of a cage and in which the surgical measures can be carried out on the aortic valve. For this it is necessary that one filter screen is placed in front and the other filter screen is placed behind the aortic valve. According to As the filter screens are opened, the aortic valve can be ablated within the volume inscribed by the filter screens. Macroscopic fragments that occur during ablation are caught by the filter screen surfaces and prevented from entering the rest of the bloodstream. After completion of the ablation and other surgical measures, the filter screens are folded up and the macroscopic particles trapped therein, as well as possibly the aortic valve removed as a whole, are enclosed. The dimensions of the filter screens are chosen such that they can be pushed through conventional hollow working catheters, so that after the surgical measure has been completed, the filter screens filled with macroscopic particles can be moved extracorporeally through a corresponding working channel.
Das Filtermaterial, aus dem die einzelnen Filterschirme bestehen, ist derart gewählt, dass die natürlichen Blutbestandteile ungehindert durch das Filtermaterial hindurchtreten können. Makroskopische Teilchen mit Teilchengrößen von mehr als 7,5 μm bleiben jedoch im Filtermaterial hängen und können entsprechend entsorgt werden.The filter material from which the individual Filter screens exist, is chosen so that the natural Blood components pass freely through the filter material can. Macroscopic particles with particle sizes of more than 7.5 μm remain however, hang in the filter material and can accordingly to be disposed of.
Kurze Beschreibung der ErfindungBrief description of the invention
Die Erfindung wird nachstehend ohne Beschränkung des allgemeinen Erfindungsgedankens anhand von Ausführungsbeispielen unter Bezugnahme auf die Zeichnung exemplarisch beschrieben. Es zeigen:The invention is hereinafter without restriction the general inventive concept based on exemplary embodiments described by way of example with reference to the drawing. Show it:
Wege zur Ausführung der Erfindung, gewerbliche VerwendbarkeitWays to Execute the Invention, industrial applicability
In
Alternativ zur der in
Zum Aufspannen der beiden Filterschirme
ist jeweils ein Schlittenelement
Im gespannten Zustand der Filterschirmanordnung
umschließen
beide Filterschirme
Zur Durchführung der Ablation einer verkalkten
Aortenklappe wird die Filterschirmanordnung im zusammengefalteten
Zustand durch eine, in der Aortenklappe vorhandene Öffnung hindurchgeschoben, so
dass ein Filterschirm
Nach entsprechender Positionierung und Zentrierung der Filterschirmanordnung innerhalb des Aortenbogens respektive nach Justierung relativ zur ablatierenden Aortenklappe zentriert sich die Filterschirmanordnung selbständig durch Aufspreizen der einzelnen Filterschirme an der Innenwandung der Aorta. Die Filterschirmanordnung dient in diesem Fall auch zugleich als mechanischer Fixpunkt bzw. Auflagemöglichkeit für die für die Ablation einzusetzenden mikrochirurgischen Instrumente. Auf diese Weise ist eine Mikronavigation der für die Ablation erforderlichen Katheterwerkzeuge erheblich vereinfacht im Vergleich zu bisherigen Techniken, bei denen eine derartige Justierhilfe nicht vorhanden ist.After appropriate positioning and centering of the filter screen arrangement within the aortic arch, or after adjustment relative to the ablating aortic valve, the filter screen arrangement centers itself by spreading the individual filter screens on the inner wall of the aorta. In this case, the filter screen arrangement also serves as a mechanical fixed point or support for the microsurgical instruments to be used for the ablation. In this way, micro-navigation of the catheter tools required for the ablation is considerably simplified compared to previous techniques in which one such adjustment aid is not available.
In
Neben dem in
- 11
- Verbindungsachseconnecting axis
- 22
- Arbeitskatheterworking catheter
- 3, 43, 4
- Filterschirmfilter screen
- 55
- Schlittenelementcarriage element
- 66
- Spreizstrebenexpansion braces
Claims (9)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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DE10049812A DE10049812B4 (en) | 2000-10-09 | 2000-10-09 | Device for filtering out macroscopic particles from the bloodstream during local removal of an aortic valve on the human or animal heart |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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DE10049812A DE10049812B4 (en) | 2000-10-09 | 2000-10-09 | Device for filtering out macroscopic particles from the bloodstream during local removal of an aortic valve on the human or animal heart |
Publications (2)
Publication Number | Publication Date |
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DE10049812A1 DE10049812A1 (en) | 2002-04-18 |
DE10049812B4 true DE10049812B4 (en) | 2004-06-03 |
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ID=7659061
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Cited By (96)
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WO2009076482A1 (en) * | 2007-12-10 | 2009-06-18 | Incept, Llc | Retrieval apparatus and methods for use |
US7758606B2 (en) | 2000-06-30 | 2010-07-20 | Medtronic, Inc. | Intravascular filter with debris entrapment mechanism |
US7780726B2 (en) | 2001-07-04 | 2010-08-24 | Medtronic, Inc. | Assembly for placing a prosthetic valve in a duct in the body |
US7846203B2 (en) | 1996-12-31 | 2010-12-07 | Edwards Lifesciences Pvt, Inc. | Implanting a stent valve prosthesis at the native aortic valve |
US7871436B2 (en) | 2007-02-16 | 2011-01-18 | Medtronic, Inc. | Replacement prosthetic heart valves and methods of implantation |
US7892281B2 (en) | 1999-11-17 | 2011-02-22 | Medtronic Corevalve Llc | Prosthetic valve for transluminal delivery |
US7914569B2 (en) | 2005-05-13 | 2011-03-29 | Medtronics Corevalve Llc | Heart valve prosthesis and methods of manufacture and use |
US7972378B2 (en) | 2008-01-24 | 2011-07-05 | Medtronic, Inc. | Stents for prosthetic heart valves |
US7993394B2 (en) | 2008-06-06 | 2011-08-09 | Ilia Hariton | Low profile transcatheter heart valve |
US8016877B2 (en) | 1999-11-17 | 2011-09-13 | Medtronic Corevalve Llc | Prosthetic valve for transluminal delivery |
US8052749B2 (en) | 2003-12-23 | 2011-11-08 | Sadra Medical, Inc. | Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements |
US8052750B2 (en) | 2006-09-19 | 2011-11-08 | Medtronic Ventor Technologies Ltd | Valve prosthesis fixation techniques using sandwiching |
US8075615B2 (en) | 2006-03-28 | 2011-12-13 | Medtronic, Inc. | Prosthetic cardiac valve formed from pericardium material and methods of making same |
US8080054B2 (en) | 2003-10-02 | 2011-12-20 | Edwards Lifesciences Corporation | Implantable prosthetic valve with non-laminar flow |
US8137398B2 (en) | 2008-10-13 | 2012-03-20 | Medtronic Ventor Technologies Ltd | Prosthetic valve having tapered tip when compressed for delivery |
US8157852B2 (en) | 2008-01-24 | 2012-04-17 | Medtronic, Inc. | Delivery systems and methods of implantation for prosthetic heart valves |
US8167932B2 (en) | 2005-10-18 | 2012-05-01 | Edwards Lifesciences Corporation | Heart valve delivery system with valve catheter |
US8182528B2 (en) | 2003-12-23 | 2012-05-22 | Sadra Medical, Inc. | Locking heart valve anchor |
US8231670B2 (en) | 2003-12-23 | 2012-07-31 | Sadra Medical, Inc. | Repositionable heart valve and method |
US8236049B2 (en) | 2008-06-20 | 2012-08-07 | Edwards Lifesciences Corporation | Multipiece prosthetic mitral valve and method |
US8241274B2 (en) | 2000-01-19 | 2012-08-14 | Medtronic, Inc. | Method for guiding a medical device |
US8246678B2 (en) | 2003-12-23 | 2012-08-21 | Sadra Medicl, Inc. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US8252052B2 (en) | 2003-12-23 | 2012-08-28 | Sadra Medical, Inc. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US8252051B2 (en) | 2009-02-25 | 2012-08-28 | Edwards Lifesciences Corporation | Method of implanting a prosthetic valve in a mitral valve with pulmonary vein anchoring |
US8312825B2 (en) | 2008-04-23 | 2012-11-20 | Medtronic, Inc. | Methods and apparatuses for assembly of a pericardial prosthetic heart valve |
US8313525B2 (en) | 2008-03-18 | 2012-11-20 | Medtronic Ventor Technologies, Ltd. | Valve suturing and implantation procedures |
US8328868B2 (en) | 2004-11-05 | 2012-12-11 | Sadra Medical, Inc. | Medical devices and delivery systems for delivering medical devices |
US8343213B2 (en) | 2003-12-23 | 2013-01-01 | Sadra Medical, Inc. | Leaflet engagement elements and methods for use thereof |
US8430927B2 (en) | 2008-04-08 | 2013-04-30 | Medtronic, Inc. | Multiple orifice implantable heart valve and methods of implantation |
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