CN204618494U - A kind of degradable composite tubular urethra rack - Google Patents

A kind of degradable composite tubular urethra rack Download PDF

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Publication number
CN204618494U
CN204618494U CN201420772790.0U CN201420772790U CN204618494U CN 204618494 U CN204618494 U CN 204618494U CN 201420772790 U CN201420772790 U CN 201420772790U CN 204618494 U CN204618494 U CN 204618494U
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CN
China
Prior art keywords
thin film
internal layer
acellular matrix
degradable
composite tubular
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201420772790.0U
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Chinese (zh)
Inventor
杜小文
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Jinhua City People S Hospital
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Jinhua City People S Hospital
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Priority to CN201420772790.0U priority Critical patent/CN204618494U/en
Application granted granted Critical
Publication of CN204618494U publication Critical patent/CN204618494U/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Abstract

This utility model is a kind of degradable composite tubular urethra rack.The purpose of this utility model causes for when existing and draw materials in existing long section urethral stricture Therapeutic Method the weak point that wound, material taken amount are limited, position of drawing materials easily leads to complications, and provides a kind of degradable composite tubular urethra rack.This utility model is a kind of degradable tissue engineering bracket, comprises internal layer and skin, and internal layer is tubulose, and skin is located on the outer surface of internal layer; Described internal layer and skin all adopt degradable macromolecular material and acellular matrix to make, and described degradable high polymer material adopts Poly(D,L-lactide-co-glycolide PLGA thin film, and described acellular matrix adopts small intestinal acellular matrix SIS thin film; Interconnect between Poly(D,L-lactide-co-glycolide PLGA thin film and small intestinal acellular matrix SIS thin film.Adopting this utility model to carry out urethra compound and reconstruction, without the need to carrying out autologous drawing materials, avoiding the complication that position of drawing materials may cause.

Description

A kind of degradable composite tubular urethra rack
Technical field
This utility model relates to medicine technology field, particularly a kind of degradable composite tubular urethra rack.
Background technology
Traumatic or iatrogenic urethral injury, the urethral stricture that the gonococcal or various factors such as nonspecific urethritis and congenital urethra pathological changes causes is one of difficult problem of facing of urological surgeon.Conventional treatments comprises urethral dilatation, internal urethrotomy, end-to-end anastomosis of urethra etc. and is only applicable to the shorter urethral stricture patient of distance, patient for long section urethral stricture mainly adopts alternative operative treatment, and genital skin, bladder mucosa, albuginea penis, oral mucosa and lingual mucous membrane are all used as the patching material of urethra prosthesis; But draw materials and usually can cause the complication at position of drawing materials, and the amount of drawing materials is restricted.
Summary of the invention
The purpose of this utility model causes for when existing and draw materials in existing long section urethral stricture Therapeutic Method the weak point that wound, material taken amount are limited, position of drawing materials easily leads to complications, and provides a kind of degradable composite tubular urethra rack.
This utility model completes in the following way: a kind of degradable composite tubular urethra rack, this degradable composite tubular urethra rack is a kind of degradable tissue engineering bracket, comprise internal layer and skin, internal layer is tubulose, and skin is located on the outer surface of internal layer; Described internal layer and skin all adopt degradable macromolecular material and acellular matrix to make.
In the degradable composite tubular urethra rack of described one, described makes internal layer and outer field degradable high polymer material employing Poly(D,L-lactide-co-glycolide PLGA thin film, and described acellular matrix adopts small intestinal acellular matrix SIS thin film; Interconnect between Poly(D,L-lactide-co-glycolide PLGA thin film and small intestinal acellular matrix SIS thin film.
In the degradable composite tubular urethra rack of described one, pass through between described Poly(D,L-lactide-co-glycolide PLGA thin film with small intestinal acellular matrix SIS thin film together with suturing with thread management; Described Poly(D,L-lactide-co-glycolide PLGA thin film and small intestinal acellular matrix SIS thin film are all in strip structure; Described line is employing 9/0 nylon wire.
In the degradable composite tubular urethra rack of described one, described skin is wrapped on the outer surface of internal layer by spiral way.
In the degradable composite tubular urethra rack of described one, Poly(D,L-lactide-co-glycolide PLGA thin film on described internal layer and the placing flat of small intestinal acellular matrix SIS film water, longitudinal separation arrangement is stitched together in the form of sheets, around catheter external latasuture synthesis tubulose.
In the degradable composite tubular urethra rack of described one, the Poly(D,L-lactide-co-glycolide PLGA thin film on described skin and small intestinal acellular matrix SIS thin film level are intervally arranged and are stitched together in strip.
In the degradable composite tubular urethra rack of described one, described internal layer is arranged by the Poly(D,L-lactide-co-glycolide PLGA thin film of two rectangles and the small intestinal acellular matrix SIS thin film longitudinal separation of two rectangles and is formed; Described skin is intervally arranged by two rectangular-shaped Poly(D,L-lactide-co-glycolide PLGA thin film and two rectangular-shaped small intestinal acellular matrix SIS thin film levels and is stitched together.
This utility model has good biocompatibility and mechanical property, has both elasticity and pliability, can keep stable tube-like condition in vivo; What this utility model adopted is polymeric biomaterial and acellular matrix, is conducive to seed cell and sticks, breeds and break up, and promotes the growth of surrounding tissue; Bi-material can progressively be decomposed into small-molecule substance by respective mode and naturally absorb in vivo, without the need to taking out.
Adopting this utility model to carry out urethra Reparation and Reconstruction, without the need to carrying out autologous drawing materials, avoiding the complication that position of drawing materials may cause; Mucous membrane of urethra epithelial cell, stem cell, smooth muscle cell etc. can adhere to and breed on support, can be directly used in urethra Reparation and Reconstruction, are applicable to clinical practice.
Accompanying drawing explanation
Fig. 1 is the structural representation of a kind of degradable composite tubular urethra rack internal layer of this utility model.
Fig. 2 is the outer field structural representation of a kind of degradable composite tubular urethra rack of this utility model.
Fig. 3 is the schematic diagram that this utility model internal layer launches.
Fig. 4 is the schematic diagram that this utility model skin launches.
In accompanying drawing 1 ~ 4,1 represents internal layer; 2 represent outer; 3 represent Poly(D,L-lactide-co-glycolide PLGA thin film; 4 represent small intestinal acellular matrix SIS thin film.
Detailed description of the invention
Contrast accompanying drawing below, by embodiment, the utility model is described in further detail.
With reference to accompanying drawing 1 ~ 4, a kind of degradable composite tubular urethra rack, this degradable composite tubular Tissue Engineering Urethra support is a kind of degradable tissue engineering bracket, and comprise internal layer 1 and outer 2, outer 2 are located on the lateral surface of internal layer 1; Described internal layer 1 is tubular structure, by two length be 30mm, width is that the Poly(D,L-lactide-co-glycolide PLGA thin film of the rectangle of 3mm and two length are 30mm, width is 3mm rectangle small intestinal acellular matrix SIS thin film longitudinal separation is arranged and is stitched together in the form of sheets, around catheter external latasuture synthesis tubulose; Outer 2 by two length be 30mm, width is that 3mm OBL Poly(D,L-lactide-co-glycolide PLGA and two length is 30mm, width is arrange and sew up and make strip in 3mm OBL small intestinal acellular matrix SIS horizontal interval, skin 2 is spirally wound on the outer surface of internal layer 1.

Claims (8)

1. a degradable composite tubular urethra rack, it is characterized in that this degradable composite tubular urethra rack is a kind of degradable tissue engineering bracket, comprise internal layer and skin, internal layer is tubulose, and skin is located on the outer surface of internal layer; Described internal layer and outer degradable macromolecular material and the acellular matrix of adopting are made.
2. the degradable composite tubular urethra rack of one according to claim 1, it is characterized in that described making internal layer and outer field degradable high polymer material adopts Poly(D,L-lactide-co-glycolide PLGA thin film, described acellular matrix adopts small intestinal acellular matrix SIS thin film; Interconnect between Poly(D,L-lactide-co-glycolide PLGA thin film and small intestinal acellular matrix SIS thin film.
3. the degradable composite tubular urethra rack of one according to claim 1 and 2, is characterized in that described skin is wrapped on the outer surface of internal layer by spiral way.
4. the degradable composite tubular urethra rack of one according to claim 2, is characterized in that between described Poly(D,L-lactide-co-glycolide PLGA thin film with small intestinal acellular matrix SIS thin film by together with suturing with thread management; Described Poly(D,L-lactide-co-glycolide PLGA thin film and small intestinal acellular matrix SIS thin film are all in strip structure.
5. the degradable composite tubular urethra rack of one according to claim 4, is characterized in that described line is employing 9/0 nylon wire.
6. the degradable composite tubular urethra rack of one according to claim 4, it is characterized in that the Poly(D,L-lactide-co-glycolide PLGA thin film on described internal layer and the placing flat of small intestinal acellular matrix SIS film water, longitudinal separation arrangement is stitched together in the form of sheets, around catheter external latasuture synthesis tubulose.
7. the degradable composite tubular urethra rack of one according to claim 4, is characterized in that Poly(D,L-lactide-co-glycolide PLGA thin film on described skin and small intestinal acellular matrix SIS thin film level are intervally arranged and are stitched together in strip.
8. the degradable composite tubular urethra rack of one according to claim 4, is characterized in that described internal layer is arranged by the Poly(D,L-lactide-co-glycolide PLGA thin film of two rectangles and the small intestinal acellular matrix SIS thin film longitudinal separation of two rectangles and forms; Described skin is intervally arranged by two rectangular-shaped Poly(D,L-lactide-co-glycolide PLGA thin film and two rectangular-shaped small intestinal acellular matrix SIS thin film levels and is stitched together.
CN201420772790.0U 2014-12-09 2014-12-09 A kind of degradable composite tubular urethra rack Expired - Fee Related CN204618494U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201420772790.0U CN204618494U (en) 2014-12-09 2014-12-09 A kind of degradable composite tubular urethra rack

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201420772790.0U CN204618494U (en) 2014-12-09 2014-12-09 A kind of degradable composite tubular urethra rack

Publications (1)

Publication Number Publication Date
CN204618494U true CN204618494U (en) 2015-09-09

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Country Status (1)

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CN (1) CN204618494U (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104473706A (en) * 2014-12-09 2015-04-01 金华市人民医院 Biodegradable composite type tubular urethral stent and preparation method
CN108939160A (en) * 2018-07-27 2018-12-07 吉林大学 A kind of artificial tubular biomaterial

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104473706A (en) * 2014-12-09 2015-04-01 金华市人民医院 Biodegradable composite type tubular urethral stent and preparation method
CN104473706B (en) * 2014-12-09 2017-02-22 金华市人民医院 Biodegradable composite type tubular urethral stent and preparation method
CN108939160A (en) * 2018-07-27 2018-12-07 吉林大学 A kind of artificial tubular biomaterial

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C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20150909

Termination date: 20171209