CN106397439A - 一种自旋标记骆驼宁碱a化合物、制备方法及其用途 - Google Patents

一种自旋标记骆驼宁碱a化合物、制备方法及其用途 Download PDF

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CN106397439A
CN106397439A CN201610814140.1A CN201610814140A CN106397439A CN 106397439 A CN106397439 A CN 106397439A CN 201610814140 A CN201610814140 A CN 201610814140A CN 106397439 A CN106397439 A CN 106397439A
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reaction
dissolved
compound
camel
ice bath
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CN106397439B (zh
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刘映前
王美娟
宋子龙
杨茜茹
成丕乐
赵永龙
陈海乐
李俊采
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Gansu Kangyang Pharmaceutical Technology Co., Ltd.
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Lanzhou University
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
CN201610814140.1A 2016-09-11 2016-09-11 一种自旋标记骆驼宁碱a化合物、制备方法及其用途 Active CN106397439B (zh)

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CN106397439B CN106397439B (zh) 2019-01-08

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102249987A (zh) * 2011-05-06 2011-11-23 兰州大学 一种考布他汀类化合物及其制备方法和用途
CN103351383A (zh) * 2013-07-29 2013-10-16 中国人民解放军第四军医大学 5-氟尿嘧啶氮氧自由基抗肿瘤药物

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102249987A (zh) * 2011-05-06 2011-11-23 兰州大学 一种考布他汀类化合物及其制备方法和用途
CN103351383A (zh) * 2013-07-29 2013-10-16 中国人民解放军第四军医大学 5-氟尿嘧啶氮氧自由基抗肿瘤药物

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,: "Luotonin-A based quinazolinones cause apoptosis and senescence via HDAC inhibition and activation of tumor suppressor proteins in HeLa cells", 《EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY》 *
XUAN TIAN ET AL.: "Antitumor and antioxidant activity of spin labeled derivatives of podophyllotoxin (GP-1) and congeners", 《LIFE SCIENCES》 *
张自义等: "稳定氮氧自由基TMPO和TMPRO的合成与应用", 《有机化学》 *
陈晓等: "2,2,6,6-四甲基-3-烯哌啶氮氧自由基鱼藤酮肟酯体外抗肿瘤作用", 《兰州大学学报(医学版)》 *

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Patentee before: Lanzhou University