CN104892668B - 考布他汀类似物水溶性前‑前药及其制备方法 - Google Patents

考布他汀类似物水溶性前‑前药及其制备方法 Download PDF

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CN104892668B
CN104892668B CN201510241243.9A CN201510241243A CN104892668B CN 104892668 B CN104892668 B CN 104892668B CN 201510241243 A CN201510241243 A CN 201510241243A CN 104892668 B CN104892668 B CN 104892668B
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prodrug
dimethylphenyl
dissolved
reaction
structural formula
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CN104892668A (zh
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鲍治成
沈卫平
卜海冬
王军福
于静
方栋
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University of Shanghai for Science and Technology
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CN108607605A (zh) * 2018-06-11 2018-10-02 徐州得铸生物科技有限公司 一种用于合成异戊烯酸甲酯的催化剂
CN112898128B (zh) * 2021-02-08 2023-07-07 苏州华道生物药业股份有限公司 红褐林蚁信息素成分3-乙基-4-甲基戊醇的合成方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5561122A (en) * 1994-12-22 1996-10-01 Arizona Board Of Regents Acting On Behalf Of Arizona State University Combretastatin A-4 prodrug
WO2002006279A1 (en) * 2000-07-17 2002-01-24 Oxigene Inc Efficient method of synthesizing combretastatin a-4 prodrugs
CN101220054A (zh) * 2008-01-29 2008-07-16 成都恒基医药科技有限公司 康普瑞汀a-4磷酸酯二钠盐的制备方法
CN102015620A (zh) * 2008-02-28 2011-04-13 赛诺菲-安万特 制备考布他汀的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1299337A4 (en) * 2000-04-27 2004-10-13 Univ Arizona State HYDROXYPHENSTATIN AND ITS PROMEDICATIONS

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5561122A (en) * 1994-12-22 1996-10-01 Arizona Board Of Regents Acting On Behalf Of Arizona State University Combretastatin A-4 prodrug
WO2002006279A1 (en) * 2000-07-17 2002-01-24 Oxigene Inc Efficient method of synthesizing combretastatin a-4 prodrugs
CN101220054A (zh) * 2008-01-29 2008-07-16 成都恒基医药科技有限公司 康普瑞汀a-4磷酸酯二钠盐的制备方法
CN102015620A (zh) * 2008-02-28 2011-04-13 赛诺菲-安万特 制备考布他汀的方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
R.Brown et al..Carbon-14 radiosynthesis of combretastatinA-1 (CA1) and its corresponding phosphate prodrug (CA1P).《J. Label Compd. Radiopharm》.2009,第52卷(第14期),第567-570页. *
夏虎雄等.考布他汀4A 磷酸酯缓释纳米粒的制备及抗肿瘤活性考察.《中国实验方剂学杂志》.2013,第19卷(第8期),第40-43页. *

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