CN104225111A - Traditional Chinese medicine composition for chronic pancreatitis treatment and preparation method application thereof - Google Patents
Traditional Chinese medicine composition for chronic pancreatitis treatment and preparation method application thereof Download PDFInfo
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- CN104225111A CN104225111A CN201410564326.7A CN201410564326A CN104225111A CN 104225111 A CN104225111 A CN 104225111A CN 201410564326 A CN201410564326 A CN 201410564326A CN 104225111 A CN104225111 A CN 104225111A
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Abstract
The invention provides a traditional Chinese medicine composition for chronic pancreatitis treatment and is prepared by utilizing the raw materials, by weight, comprising 13 parts of didymocarpus yunnanensis, 14 parts of diploclisia glaucescens, 10 parts of dodartia orientalis, 12 parts of elatostema obtusum, 16 parts of epilobium parviflorum, 12 parts of rhizome of Asian baneberry, 14 parts of brachystemma calycinum, 16 parts of acorus gramineus, 12 parts of gluey bark litse, 15 parts of cyathula prostrata, 12 parts of lysimachia capillipes hemsl, 14 parts of ixeris japonica, 8 parts of berchemia yunnanensis franch, 16 parts of calogyne pilosa, 13 parts of mesona blumes, 12 parts of zygophyllum fabago, 10 parts of cavalerie mosla herb, 12 parts of caibiodendron yunnanensel and 14 parts of passion flower. The traditional Chinese medicine composition for chronic pancreatitis treatment can be used for treating chronic pancreatitis.
Description
Technical field
The present invention relates to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine composition and the preparation method and application that treat chronic pancreatitis.
Background technology
Chronic pancreatitis is pancreatic parenchmal progressive injury because the factor such as biliary tract or alcoholism causes and fibrosis, often accompanies calcification, pseudocyst and islet cells to reduce or atrophy.Main manifestations for suffering from abdominal pain, become thin, malnutrition, diarrhoea or steatorrhea, abdominal mass, jaundice and diabetes etc. can be there are in the later stage.Lack effective medicine at present.
Summary of the invention
Goal of the invention: in order to solve the problem, the object of the present invention is to provide a kind of Chinese medicine composition and the preparation method and application that treat chronic pancreatitis.
Technical scheme: the object of the invention is by following scheme realize:
Treat a Chinese medicine composition for chronic pancreatitis, it is prepared by the raw material of following parts by weight: Yunnan long capsule lettuce tongue 13g, pale title hook wind 14g, wild linum 10g, blunt leaf Zlatostema involucratum Franch. Et savat. 12g, little Hua LIUYECAI 16g, Rhizoma actaeae asiaticae 12g, Brachystemma calycina D. Don. 14g, conveniently fragrant 16g, purling withered tree 12g, Herba Cyathulae Prostratae 15g, Herba lysimachiae capillipedis 12g, Herba ixeritis debilis 14g, the public blue or green 8g of duck, from root fragrant 16g, Herba mesonae chinensis 13g, camel hoof lobe 12g, star color careless 10g, Folium Craibiodendri Yunnanensis 12g, turn heart lotus 14g.
The application of Chinese medicine composition in the medicine of preparation treatment chronic pancreatitis of described treatment chronic pancreatitis.
In the present invention, Yunnan long capsule lettuce tongue is a kind under Gesneriaceae Didymocarpus.Latin is called Didymocarpus yunnanensis (Franch.) W.W.Smith, produces Yunnan, South-west Sichuan, Northeastern India.Herb: lung qi dispersing cough-relieving, dissipating blood stasis for subsidence of swelling, hemostasis and pain-relieving, promotes wound healing.For cough, bronchitis, impairment caused by overstrain lumbago, swelling and pain due to blood stasis, external treatment weapons are hindered, traumatic injury, fracture.The present invention is with all herbal medicine.
Pale title hook wind is the rattan of menispermaceae plant Caulis Diploclisiae Glaucescentis, and Latin is called Diploclisia glaucescens (Bl.) Diels, produces south China, Yunnan, Fujian, Jiangxi.Ratan, leaf: heat-clearing and toxic substances removing, expelling wind and removing dampness.For rheumatic ostalgia, urine leaching pain, urinary tract infection, cholecystitis, throat pain, dysentery, venom.
Wild linum is that the wild linum of Scrophulariaceae belongs to perennial vertical herbage, high 15-50 centimetre, without hair or young tender time thin by pubescence.Latin is called Dodartia orientalis L., produces the Inner Mongol, Ningxia, Gansu, Xinjiang, Sichuan, Mongolia, the Soviet Union, Iran.Heat-clearing and toxic substances removing, loose wind is antipruritic.For senile chronic tracheitis, cough phlegm dyspnea, infantile pneumonia, tonsillitis, lymphadenitis, tonsillitis, acute mastitis, conjunctivitis, conjunctival congestion, urinary tract infection, urine leaching pain, suffers from a deficiency of the kidney.Outer for eczema, urticaria, skin pruritus, neurasthenia.The present invention is with all herbal medicine.
Blunt leaf Zlatostema involucratum Franch. Et savat. is the plant of Urticaceae Elatostematis E.Latin is called Elatostema obtusum Wedd., produces Shaanxi, Gansu, Hubei, Sichuan, Yunnan, Tibet.Herb: heat-clearing and toxic substances removing, stasis-dispelling and pain-killing.The present invention is with all herbal medicine.
Little Hua LIUYECAI is Oenotheraceae Epilobium herbaceos perennial, and Latin is called Epilobium parviflorum Schreb., produces northeast, Central China, Shaanxi, Gansu, Xinjiang.Herb: heat-clearing and toxic substances removing, dispelling wind antitussive.Root: for impairment caused by overstrain lumbago.Herb: for having loose bowels, furuncle, cough.The present invention is with all herbal medicine.
Rhizoma actaeae asiaticae is Ranunculaceae baneberry cohosh Actaea asiatica Hara, with root stock and all herbal medicine.Autumn gathers, and dries respectively.Clearing away lung-heat to relieve cough, heat-clearing and toxic substances removing.For headache due to common cold, pertussis.Lyssodexis is controlled in external.The present invention is with all herbal medicine.
Brachystemma calycina D. Don. is Caryophyllaceae Brachystemma calycina D. Don. platymiscium Brachystemma calycina D. Don. Brachystemma calycinum D.Don, is used as medicine with whole herb with root.The whole year can adopt, and cleans, using fresh herb or dry.Heat-clearing and toxic substances removing, relaxing muscles and tendons and activating QI and blood in the collateral.Root: for diphtheria, rheumatic arthralgia, traumatic injury, menoxenia, weak after being ill.Stem, leaf: carpopedal spasm is controlled in external, fracture.
Fragrant is conveniently Acorus of Araceae plant fragrant Acorus gramineus Soland.var.pusillus Engl. conveniently, and f.suaveolens C.Y.Cheng, mss., with all herbal medicine.The four seasons can adopt, and dry.Promoting the circulation of QI to relieve pain, dispel the wind by cold, removing toxic substances diuretic, eliminates phlegm for resuscitation.For mental confusion due to phlegm, coma, gnathospasma, stomachache uncomfortable in chest, turbid damp obstructing in middle-JIAO, rheumatic arthritis, colic, edema; Innominate toxic swelling is controlled in external.
Purling withered tree is purling withered tree Litsea glutinosa (Lour.) C.B.Rob. of Lauraceae Litsea plant, is used as medicine with root, skin, leaf, clearing away damp-heat, detumescence poison, hemostasis, pain relieving.Root: take orally and control diarrhoea, traumatic injury, parotitis, diabetes.Skin, leaf: parotitis is controlled in external, furuncle carbuncle, mastitis from the beginning of, traumatic injury, traumatic hemorrhage.The present invention is used as medicine with root
Herba Cyathulae Prostratae is Amaranthaceae Herba Cyathulae Prostratae platymiscium Herba Cyathulae Prostratae Cyathula prostrata (L.) Blume, with root or all herbal medicine.The four seasons can adopt, using fresh herb or dry.: root: heat-clearing and toxic substances removing.For bacillary dysentery.Herb: removing food stagnancy expectorant, reducing swelling and alleviating pain.For infantile malnutrition, hepatosplenomegaly, pulmonary tuberculosis, venom, traumatic injury, sore swollen toxin.The present invention is with all herbal medicine.
Herba lysimachiae capillipedis is the herb that Primulaceae Lysimachia plant carefully obstructs Herba lysimachiae capillipedis Lysimachia capillipes Hemsl..Xia Qiu gathers, and dries in the shade.Dispel the wind, cough-relieving, regulating menstruation.For cold cough, tracheitis, asthma, menoxenia, neurasthenia.
Herba ixeritis debilis is Compositae Ixeris Cass plant Herba ixeritis debilis Ixeris debilis A.Gray, with all herbal medicine.Xia Qiu gathers, using fresh herb or dry.Clearing away heat and cooling blood, inducing diuresis to remove edema.For cough due to lung-heat, laryngalgia, oral ulcer, acute conjunctivitis, appendicitis, edema, dysuria; Mastitis are controlled in external, furuncle toxic swelling, skin pruritus.
The public green grass or young crops of duck is Rhamnaceae hook fold plant Yunnan Radix Berchemiae Giraldianae Berchemia yunnanensis Franch., is used as medicine with root, leaf.Qiu Caigen, Xia Caiye, dry, clearing away heat-damp and promoting diuresis, dispelling, collateral-activating, promoting blood circulation and stopping pain.For jaundice, oedema due to nephritis, dysentery, redly collapses, leucorrhea, rheumatic ostalgia, dysmenorrhea; Fracture is controlled in external, traumatic injury, carbuncle sore tumefacting virus.The present invention is with all herbal medicine.
Be Goodeniaceae Calogyne plant from root fragrant Calogyne pilosa R.Brown from root perfume, with all herbal medicine.Xia Qiucai, dries.Promoting blood circulation to remove blood stasis, pain relieving, removing toxic substances.For traumatic injury, venom.
Herba mesonae chinensis is labiate, and the lower portion of the stem is thrown oneself on the ground, and top is upright, the avette or ovum shape Long Circle of leaf, and tip is slightly blunt, and base portion gradually closing shortens handle into, and there is little sawtooth at edge, and two sides all has to dredge becomes mildewed; The leaf being born in inflorescence top less, in bracteal, avette to del, comparatively spend short, base portion is often with lavender, comes off during result.Raceme is weak, spends little, and verticillate, calyx is little, mitriform, 2 lips, and upper lip 3 splits, the full edge of lower lip, during result or tubular, lower curved, has longitudinal vein and horizontal wrinkle; Corolla pale red, upper lip is wealthy, full edge or fissure, lower lip oblong, depression; Stamen 4, filigree is given prominence to; Gynoecium 1, style 2 splits; Floral disc is while expand.Pyrene is oval.Autumn Mo at florescence.Distribution south China.Classification system is Mesona chinensis Benth., clearing away heat-damp and promoting diuresis, removing heat from blood expelling summer-heat.For acute rheumatic arthritis, hypertension, heatstroke, flu, jaundice, acute nephritis, diabetes.The present invention is with all herbal medicine.
Camel hoof lobe is zygophyllaceae zygophyllum plant Zygopetalum fabago L. Zygophyllum fabago L., is used as medicine with root.Xia Qiu excavates, and dries or processed with honey.Eliminating phlegm and stopping cough, analgesic antiphlogistic.For bronchitis, flu, toothache, intractable headache.
Star color grass is followed closely platymiscium for Dianthus chinensis actions and spoken parts in classical Chinese drama drum and is roused the herb following closely Polycarpaea corymbosa Lam. in vain.Spring and autumn gathers, and cleans and dries.Heat-clearing and toxic substances removing, dehumidifying diuresis.For acute bacillary dysentery, enteritis, case of a physically strong patient running a high fever ascites, dyspepsia.The present invention is with all herbal medicine.
Folium Craibiodendri Yunnanensis is the leaf of the false Cortex Schimatis superbae Radicis in ericad Yunnan.Eliminating stasis to stop pain, expelling wind and removing dampness, stops blooding sensible.For traumatic injury, traumatic stupor, bruise, lumbago and skelalgia, hemiplegia, paralysis, rheumatic arthritis, traumatic hemorrhage, fracture.
Turning heart lotus is Passifloraceae Passiflora plant Herba Passiflorae Caeruleae Passiflora caerulea L., is used as medicine with root, Teng Heguo.Gather during fruit maturation in autumn, dry; Adopt root, rattan again, dry respectively.Expelling wind and removing dampness, promoting blood circulation and stopping pain.For rheumatic ostalgia, colic, dysmenorrhea; Fracture is controlled in external.The present invention is used as medicine with root.
Beneficial effect: the medicine that the present invention obtains can safe and effective treatment chronic pancreatitis.
Detailed description of the invention
Form by the following examples, foregoing of the present invention is described in further detail again, but this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following example, all technology realized based on foregoing of the present invention all belong to scope of the present invention.
1, specific embodiment 1: take Yunnan long capsule lettuce tongue 13g, pale title hook wind 14g, wild linum 10g, blunt leaf Zlatostema involucratum Franch. Et savat. 12g, little Hua LIUYECAI 16g, Rhizoma actaeae asiaticae 12g, Brachystemma calycina D. Don. 14g, conveniently fragrant 16g, purling withered tree 12g, Herba Cyathulae Prostratae 15g, Herba lysimachiae capillipedis 12g, Herba ixeritis debilis 14g, the public blue or green 8g of duck, from root fragrant 16g, Herba mesonae chinensis 13g, camel hoof lobe 12g, star color grass 10g, Folium Craibiodendri Yunnanensis 12g, turn heart lotus 14g, add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell, the capsule of adult normal's 1 day consumption must be met.Be used for the treatment of chronic pancreatitis.Oral, every bu is taken for twice sooner or later.
2, specific embodiment 2: take Yunnan long capsule lettuce tongue 13g, pale title hook wind 14g, wild linum 10g, blunt leaf Zlatostema involucratum Franch. Et savat. 12g, little Hua LIUYECAI 16g, Rhizoma actaeae asiaticae 12g, Brachystemma calycina D. Don. 14g, conveniently fragrant 16g, purling withered tree 12g, Herba Cyathulae Prostratae 15g, Herba lysimachiae capillipedis 12g, Herba ixeritis debilis 14g, the public blue or green 8g of duck, from root fragrant 16g, Herba mesonae chinensis 13g, camel hoof lobe 12g, star color grass 10g, Folium Craibiodendri Yunnanensis 12g, turn heart lotus 14g, add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, add starch, technique is granulated routinely, must meet the granule of adult normal's 1 day consumption.Be used for the treatment of chronic pancreatitis.Oral, every bu is taken for twice sooner or later.
3, specific embodiment 3: take Yunnan long capsule lettuce tongue 13g, pale title hook wind 14g, wild linum 10g, blunt leaf Zlatostema involucratum Franch. Et savat. 12g, little Hua LIUYECAI 16g, Rhizoma actaeae asiaticae 12g, Brachystemma calycina D. Don. 14g, conveniently fragrant 16g, purling withered tree 12g, Herba Cyathulae Prostratae 15g, Herba lysimachiae capillipedis 12g, Herba ixeritis debilis 14g, the public blue or green 8g of duck, from root fragrant 16g, Herba mesonae chinensis 13g, camel hoof lobe 12g, star color grass 10g, Folium Craibiodendri Yunnanensis 12g, turn heart lotus 14g, add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, add starch, technique is granulated routinely, and tabletting, can obtain the tablet meeting adult normal's 1 day consumption.Be used for the treatment of chronic pancreatitis.Oral, every bu is taken for twice sooner or later.
4. the present invention is to the clinical research of chronic pancreatitis
4.1, physical data: inventor collects the out-patient of 70 routine chronic pancreatitiss-2012 years in Augusts, 2010 altogether between December, age 37-57 year, course of disease 1-4.Be divided at random: treatment group 40 example, blank group 30 example.The two groups of data such as age, state of an illness there was no significant differences, have comparability.
Diagnostic criteria: (1) abdominal part B: have pancreatolith to exist in super pancreatic tissue.(2) CT: calcification in pancreas, confirms there is pancreatolith.(3) ERCP: the irregular expansion of ductus pancreaticus and branch thereof in pancreatic tissue and skewness; Main pancreatic duct partially or completely blocks, containing pancreatolith or albumen embolus.(4) secretion test: heavy carbonate secretion reduces, the secretion of companion's pancreatin or output, reduce.(5) histological examination: the visible pancreatic exocrine tissue of tissue slice destroys, reduces, and has the irregular fibrosis of lamellar between lobule, but between lobule, fibrosis is not that chronic pancreatitis institute is peculiar.(6) Epithelial hyperplasia or atypical hyperplasia, cyst are formed.
4.2, test method
4.2.1 the oral the present invention for the treatment of group is according to the obtained capsule of specific embodiment 1, sooner or later each once.15 days courses for the treatment of.
4.2.2 blank group oral placebo capsule, sooner or later respectively once.15 days courses for the treatment of.
4.3, criterion of therapeutical effect and therapeutic outcome
4.3.1 criterion of therapeutical effect
Recovery from illness: clinical symptoms all disappears, and test chamber inspection is normal.Take a turn for the better: clinical symptom relief, the state of an illness is controlled, lab testing improvement or normal.Invalid: clinical symptoms is without being clearly better or increasing the weight of.
4.3.2 statistical result is treated in table 1.
Table 1 liang group comparitive study
| Group | n | Recovery from illness | Take a turn for the better | Invalid | Total effective rate (%) |
| Treatment group | 40 | 17 | 13 | 10 | 75 |
| Blank group | 30 | 1 | 2 | 27 | 10 |
Visible, the medicine that the present invention obtains can safe and effective treatment chronic pancreatitis.
Claims (2)
1. treat the Chinese medicine composition of chronic pancreatitis for one kind, it is characterized in that, it is prepared by the raw material of following parts by weight: Yunnan long capsule lettuce tongue 13 parts, pale title hook wind 14 parts, wild linum 10 parts, blunt leaf Zlatostema involucratum Franch. Et savat. 12 parts, little Hua LIUYECAI 16 parts, Rhizoma actaeae asiaticae 12 parts, Brachystemma calycina D. Don. 14 parts, conveniently fragrant 16 parts, purling 12 parts, withered tree, Herba Cyathulae Prostratae 15 parts, Herba lysimachiae capillipedis 12 parts, Herba ixeritis debilis 14 parts, public blue or green 8 parts of duck, from fragrant 16 parts of root, Herba mesonae chinensis 13 parts, camel hoof lobe 12 parts, star color grass 10 parts, Folium Craibiodendri Yunnanensis 12 parts, turn 14 parts, heart lotus.
2. treat the application of Chinese medicine composition in the medicine for the treatment of chronic pancreatitis of chronic pancreatitis as claimed in claim 1.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005053818A (en) * | 2003-08-01 | 2005-03-03 | Yakult Honsha Co Ltd | Trypsin inhibitor |
| CN1698754A (en) * | 2005-05-16 | 2005-11-23 | 赵正夫 | Medicine for treating acute and chronic pancreatitis |
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- 2014-10-22 CN CN201410564326.7A patent/CN104225111A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005053818A (en) * | 2003-08-01 | 2005-03-03 | Yakult Honsha Co Ltd | Trypsin inhibitor |
| CN1698754A (en) * | 2005-05-16 | 2005-11-23 | 赵正夫 | Medicine for treating acute and chronic pancreatitis |
Non-Patent Citations (1)
| Title |
|---|
| 刘启廷等: "《常见病一方通用经验方》", 30 April 2013, 中医古籍出版社 * |
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