CN104151452B - 聚n‑(2‑羟丙基)甲基丙烯酰胺‑氯尼达明大分子前药及其制备方法 - Google Patents

聚n‑(2‑羟丙基)甲基丙烯酰胺‑氯尼达明大分子前药及其制备方法 Download PDF

Info

Publication number
CN104151452B
CN104151452B CN201410335603.7A CN201410335603A CN104151452B CN 104151452 B CN104151452 B CN 104151452B CN 201410335603 A CN201410335603 A CN 201410335603A CN 104151452 B CN104151452 B CN 104151452B
Authority
CN
China
Prior art keywords
hydroxypropyl
lnd
methacrylamide
poly
lonidamine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201410335603.7A
Other languages
English (en)
Chinese (zh)
Other versions
CN104151452A (zh
Inventor
张娟
张亚洲
邢晓虎
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Northwest University
Original Assignee
Northwest University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Northwest University filed Critical Northwest University
Priority to CN201410335603.7A priority Critical patent/CN104151452B/zh
Publication of CN104151452A publication Critical patent/CN104151452A/zh
Application granted granted Critical
Publication of CN104151452B publication Critical patent/CN104151452B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

CN201410335603.7A 2014-07-16 2014-07-16 聚n‑(2‑羟丙基)甲基丙烯酰胺‑氯尼达明大分子前药及其制备方法 Expired - Fee Related CN104151452B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201410335603.7A CN104151452B (zh) 2014-07-16 2014-07-16 聚n‑(2‑羟丙基)甲基丙烯酰胺‑氯尼达明大分子前药及其制备方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201410335603.7A CN104151452B (zh) 2014-07-16 2014-07-16 聚n‑(2‑羟丙基)甲基丙烯酰胺‑氯尼达明大分子前药及其制备方法

Publications (2)

Publication Number Publication Date
CN104151452A CN104151452A (zh) 2014-11-19
CN104151452B true CN104151452B (zh) 2017-02-01

Family

ID=51877095

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201410335603.7A Expired - Fee Related CN104151452B (zh) 2014-07-16 2014-07-16 聚n‑(2‑羟丙基)甲基丙烯酰胺‑氯尼达明大分子前药及其制备方法

Country Status (1)

Country Link
CN (1) CN104151452B (it)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993025197A1 (en) * 1992-06-12 1993-12-23 Affymax Technologies N.V. Compositions and methods for enhanced drug delivery
CN102159257A (zh) * 2008-07-17 2011-08-17 米歇尔技术公司 药物递送医疗设备
CN102488906A (zh) * 2011-12-13 2012-06-13 扬州大学 超顺磁导电γ-氧化铁/聚苯胺-氯尼达明及制备方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993025197A1 (en) * 1992-06-12 1993-12-23 Affymax Technologies N.V. Compositions and methods for enhanced drug delivery
CN102159257A (zh) * 2008-07-17 2011-08-17 米歇尔技术公司 药物递送医疗设备
CN102488906A (zh) * 2011-12-13 2012-06-13 扬州大学 超顺磁导电γ-氧化铁/聚苯胺-氯尼达明及制备方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
"聚N-(2-羟丙基)甲基丙烯酰胺-肼屈嗪前药的合成及表征";张娟等;《西北大学学报（自然科学版）》;20140225;第44卷(第1期);第57-60页 *

Also Published As

Publication number Publication date
CN104151452A (zh) 2014-11-19

Similar Documents

Publication Publication Date Title
CN102234259B (zh) 含笑内酯衍生物,其药物组合物及其制备方法和用途
CN104447777B (zh) 一种辣椒碱-喜树碱类抗癌药物偶联物及其制备方法和应用
CN103705940A (zh) 一种天然活性药物-多糖靶向复合物的制备及其抗肿瘤的应用
CN100545164C (zh) 斑蝥酸钠的制备工艺
CN101134109A (zh) 一种抗癌前药及其制备方法和用途
CN106749089A (zh) 新型氟代噻唑腙类化合物的制备及其在抗肿瘤药物中的应用
CN104208704B (zh) 一种pH敏感的碳纳米管靶向递药体系的制备方法
CN104707148A (zh) 一种用于抗肝癌的聚乙二醇改性甘草次酸和姜黄素复合物及其制备方法
CN101307038A (zh) 4-苄基哌连乙亚胺酰(亚胺甲基苯)肼类化合物、其制备方法、药物组合物和用途
CN103796647A (zh) 用于治疗脑癌的方法和组合物
CN104127882A (zh) 一种靶向传递紫杉醇抗癌前药的超分子组装体及制备方法
CN103923256A (zh) 叶酸-苯甲醛氮芥-hpma高分子共聚物及其制备和应用
CN104557909B (zh) 3-酰氧基取代右旋去氧娃儿藤宁衍生物、其制法和药物组合物与用途
CN102030765B (zh) 以醚键结合的卟啉二聚体盐及其制造方法
CN108707183A (zh) 酪丝亮肽-二氢卟吩e6单酯及其制备方法
CN104151452B (zh) 聚n‑(2‑羟丙基)甲基丙烯酰胺‑氯尼达明大分子前药及其制备方法
CN106924732A (zh) 一种超声治疗用肿瘤靶向型血卟啉注射剂及其制备方法
CN105435241A (zh) 一种iRGD-抗癌药物偶联物及其制备方法和应用
CN104744518B (zh) 金属钌配合物及其制备方法和应用
CN115487171A (zh) 一种透明质酸-异甘草素偶联物、溶解型微针贴及制备方法和应用
CN104524598B (zh) 一种携NET‑1siRNA的双功能肝癌靶向纳米微泡的制备方法
CN103599078A (zh) 复方鸦胆子油脂质体冻干粉的制备方法
CN103656669A (zh) 基于复合胶束的纳米载体、其制备方法及应用
CN106565718A (zh) 含硒化合物及其用途
CN1709418A (zh) 草豆蔻提取物及其制备

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20170201

Termination date: 20170716