CN103848778B - 一种氨肽酶n抑制剂及其制备方法与应用 - Google Patents

一种氨肽酶n抑制剂及其制备方法与应用 Download PDF

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Publication number: CN103848778B
Authority: CN; China
Prior art keywords: aminopeptidase; compound; inhibitor; preparation; cell
Prior art date: 2014-03-28
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

CN201410123847.9A

Other languages

English (en)

Chinese (zh)

Other versions

CN103848778A (zh

Inventor

张晓攀

马文泉

徐文方

刘刚

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

WEIFANG HIGH-TECH BIOLOGICAL PARK DEVELOPMENT Co Ltd

Original Assignee

WEIFANG HIGH-TECH BIOLOGICAL PARK DEVELOPMENT Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2014-03-28

Filing date

2014-03-28

Publication date

2016-01-06

2014-03-28 Application filed by WEIFANG HIGH-TECH BIOLOGICAL PARK DEVELOPMENT Co Ltd filed Critical WEIFANG HIGH-TECH BIOLOGICAL PARK DEVELOPMENT Co Ltd

2014-03-28 Priority to CN201410123847.9A priority Critical patent/CN103848778B/zh

2014-06-11 Publication of CN103848778A publication Critical patent/CN103848778A/zh

2016-01-06 Application granted granted Critical

2016-01-06 Publication of CN103848778B publication Critical patent/CN103848778B/zh

Status Expired - Fee Related legal-status Critical Current

2034-03-28 Anticipated expiration legal-status Critical

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Classifications

- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

CN201410123847.9A 2014-03-28 2014-03-28 一种氨肽酶n抑制剂及其制备方法与应用 Expired - Fee Related CN103848778B (zh)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
CN201410123847.9A CN103848778B (zh)	2014-03-28	2014-03-28	一种氨肽酶n抑制剂及其制备方法与应用

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CN201410123847.9A CN103848778B (zh)	2014-03-28	2014-03-28	一种氨肽酶n抑制剂及其制备方法与应用

Publications (2)

Publication Number	Publication Date
CN103848778A CN103848778A (zh)	2014-06-11
CN103848778B true CN103848778B (zh)	2016-01-06

Family

ID=50856941

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CN201410123847.9A Expired - Fee Related CN103848778B (zh)	2014-03-28	2014-03-28	一种氨肽酶n抑制剂及其制备方法与应用

Country Status (1)

Country	Link
CN (1)	CN103848778B (it)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN108977498B (zh) *	2018-06-19	2022-09-20	潍坊医学院	一种氨肽酶n抑制剂的抑酶活性测定方法及应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN1974554A (zh) *	2006-12-12	2007-06-06	山东大学	环酰亚胺类肽金属蛋白酶抑制剂及其应用
CN101538311A (zh) *	2009-04-16	2009-09-23	山东大学	α-氨基酰环酰亚胺类肽金属蛋白酶抑制剂及其应用

2014
- 2014-03-28 CN CN201410123847.9A patent/CN103848778B/zh not_active Expired - Fee Related

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN1974554A (zh) *	2006-12-12	2007-06-06	山东大学	环酰亚胺类肽金属蛋白酶抑制剂及其应用
CN101538311A (zh) *	2009-04-16	2009-09-23	山东大学	α-氨基酰环酰亚胺类肽金属蛋白酶抑制剂及其应用

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
(S)-5-乙酰胺甲基-3-[(4-取代胺甲基)苯基]-2- 噁唑烷酮衍生物的合成及抗菌活性;李荣坡等;《药学学报》;20061231;第41卷(第5期);第418-425页 *
叠氮化合物还原成胺的研究进展;王晓季;《化学通报》;20041231(第6期);第418-424页 *
脲基类肽氨酶N抑制剂的设计合成及其抗肿瘤活性研究;宿莉;《中国博士学位论文全文数据库医药卫生科技辑》;20120630(第06期);第44页第2段，第43页第1段，第48页-第50页，第119页 *

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Publication number	Publication date
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Legal Events

Date	Code	Title	Description
2014-06-11	C06	Publication
2014-06-11	PB01	Publication
2014-07-09	C10	Entry into substantive examination
2014-07-09	SE01	Entry into force of request for substantive examination
2016-01-06	C14	Grant of patent or utility model
2016-01-06	GR01	Patent grant
2019-03-19	CF01	Termination of patent right due to non-payment of annual fee	Granted publication date: 20160106 Termination date: 20180328
2019-03-19	CF01	Termination of patent right due to non-payment of annual fee