CN103120818A - Injection pump possessing improved flow monitoring - Google Patents

Injection pump possessing improved flow monitoring Download PDF

Info

Publication number
CN103120818A
CN103120818A CN2012104436951A CN201210443695A CN103120818A CN 103120818 A CN103120818 A CN 103120818A CN 2012104436951 A CN2012104436951 A CN 2012104436951A CN 201210443695 A CN201210443695 A CN 201210443695A CN 103120818 A CN103120818 A CN 103120818A
Authority
CN
China
Prior art keywords
syringe
flow
syringe pump
pump according
transducer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN2012104436951A
Other languages
Chinese (zh)
Other versions
CN103120818B (en
Inventor
李朝阳
张梅
吕存有
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zyno Medical LLC
Original Assignee
Zyno Medical LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zyno Medical LLC filed Critical Zyno Medical LLC
Publication of CN103120818A publication Critical patent/CN103120818A/en
Application granted granted Critical
Publication of CN103120818B publication Critical patent/CN103120818B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Abstract

The present invention discloses an injection pump possessing improved flow monitoring. The injection pump controls the amount of a medicine supplied by an injector by the movement of a plunger of the injector, at the same time, utilizes a flow sensor to monitor the flow of the injector. In the control of the plunger of the injector and the actual flow, the implied simultaneous monitoring to a flow instruction provides an irregularity detection during the medicine transmission process and an additional safety.

Description

Syringe pump with improved flow monitoring
The cross reference of related application
The application requires the priority of the U.S. Provisional Application 61/552,300 of submission on October 27th, 2011, and the full content with this application is herein incorporated by reference.
Technical field
The present invention relates to the syringe pump for medical purpose, and relate more specifically to provide the syringe pump of monitoring operation better.
Background technology
The known injection pump was used for giving (administer) a certain amount of fluid to the patient within certain period, for example medicament or contrast agent (hereinafter referred to as medicine).Such pump uses following syringe, and this syringe is included in the plunger that slides in syringe.This plunger comprises the piston type sealing member, and this piston type sealing member is against the inner surface of syringe and closely adaptive.The movement of plunger reduces to be included in the volume between the outlet of plunger seal and syringe in syringe, so that positive emission type (positive displacement) pump action to be provided.
Syringe pump comprises injection drive, and this injection drive provides the movement of plunger about pipe via motor.Motor can provide accurately and slowly moving of plunger, in order in the situation that need not people's operation delivery of intravenous medicine in several minutes.Can control flow rate by the geometry of knowing syringe and the movement of controlling exactly syringe.
Standard vein (intravenous, IV) conduit that syringe pump can have hypodermic needle by termination etc. is connected to the patient.
Summary of the invention
The invention provides a kind of syringe pump with the monitoring of improved flow rate, this syringe pump can be for detection of the problem in the IV conduit or IV conduit and problem in being connected of the patient in syringe downstream.Monitor the flow rate that is independent of the known motion of syringe and derives and allow to determine the disconnection of IV conduit or the problem that stream is obstructed.By use sensor on downstream tube, make monitoring flow rate and feasible such as other traffic conditions such as bubble in pressure and stream.Can from the outside flow monitoring of carrying out of IV conduit to keep the gnotobasis of IV conduit, perhaps can in pre-sterilized unit, flow monitoring be integrated in the IV conduit.
What it will be appreciated that is, the structure of the assembly that application of the present invention is not limited to here set forth and the details of layout.The present invention can have other embodiment and can carry out in every way or implement.The variants and modifications of aforementioned content within the scope of the invention.What it is also to be understood that is, open and the present invention that limit here can expand to by mention in text and/or accompanying drawing or apparent each feature in all alternative combinations of two or more features.All these various combinations consist of each alternative aspect of the present invention.The embodiments described herein has illustrated that known being used for implement optimal mode of the present invention, and will make others skilled in the art can utilize the present invention.
Description of drawings
Fig. 1 is the block diagram according to syringe pump of the present invention, and shows syringe and injection drive, injection drive and control compunication, and this is controlled computer and also receives signal from the IV catheter sensor in downstream;
Fig. 2 is the simplified perspective view of an embodiment of injection drive of the present invention, shows by the IV conduit being pressed into the IV conduit that carries out in passage to engage with the side direction of downstream sensor;
Fig. 3 is suitable for the simplified cross-sectional view of crossing pipe (through-tubing) pressure transducer of the present invention;
Fig. 4 is suitable for the simplified cross-sectional view that mistake of the present invention is managed air bubble sensor;
Fig. 5 is the simplified cross-sectional view of crossing pipe flow amount rate monitor that adopts the pressure transducer of two types shown in Figure 3;
Fig. 6 adopts hyperacoustic simplified cross-sectional view of crossing pipe flow amount rate monitor;
Fig. 7 is the simplified cross-sectional view that adopts the interior integrated form flow transducer of pipe of rotating machinery element;
Fig. 8 is the simplified cross-sectional view that adopts the interior integrated form flow transducer of pipe of heating element heater and heat sensor;
Fig. 9 adopts the simplified cross-sectional view of the pipe flow amount of the crossing speed watch-dog of optical sensor to show;
Figure 10 shows the partial view of needle end of the IV pipe of the alternate embodiment that adopts the long range positioning pressure transducer; And
Figure 11 is the flow chart of the program that is used for the operation of monitoring syringe pump that can be carried out by the controller of Fig. 1.
The specific embodiment
Referring now to Fig. 1, syringe pump 10 of the present invention can adopt syringe 12, and this syringe 12 is similar to common hypodermic syringe and has syringe 14, and this syringe 14 has the first opening 16 that receives plunger 18.The end of plunger 18 in syringe 14 is connected to piston seal 20 (for example being elastomeric material), and this piston seal 20 adapts in the volume of syringe 14 tightly.
Second end 22 (relative with opening 16) of syringe 14 is such as being connected to IV pipe 24 by Rule (luer) adapter 26 grades, so that the continuous path of 28 of Rule adapter 26 of being included in IV pipe 24 and the subcutaneous injection volumes between piston seal 20 to be provided.
IV pipe 24 can be for highly being obedient to (compliant) material, its can be can sterilize and be preferably apyrogeneity, without DEHP and do not contain latex (latex).A kind of such material is silicone rubber, and it provides high compliance, as desired in following pressure sensing.Another is exemplified as the material without DEHP PVC.Through air bubble sensor 32, pressure transducer 30 and flow transducers 33, and IV pipe 24 can be by in the gap between the opposing sidewalls that is pressed against in air bubble sensor 32 and flow transducer 33 each and be pressed against by the supporter 79 on following lid 68 and be installed on pressure transducer 30 in air bubble sensor 32, pressure transducer 30 and flow transducer 33 from syringe 12 for IV pipe 24.Then IV pipe 24 can enter into patient end 34, and IV pipe 24 is attached to hypodermic needle 36, catheter or other patient's connector there.
Plunger 18 leaves piston seal 20 and the part that extends to outside syringe can be connected to injection drive 38.Injection drive 38 comprises plunger piece 40, and this plunger piece 40 is constrained under the driving of motor 42 the axis Linear-moving along syringe 14.Motor 42 can be such as being step-by-step motor or servomotor etc., and comprise and reduce and will rotatablely move to convert the suitable mechanism of linear movement to for speed, such as realizing by linear screw, rack and pinion or belt transmission etc.Motor 42 receives electric power so that the movement of plunger piece 40 to be provided from motor controller 48, thereby with controllable rate and controlled distance mobile piston sealing member 20 volume through syringes 14.Such as understood in the art, can communicate by letter the controlled motion that provides such with motor controller 48 with various positions such as encoder, tachoscope and limit switch or velocity sensor.In addition, sensor can provide based on the known dimensions of syringe 14 estimating from first of the drug flux of syringe.
Electronic controller 44 can be coordinated by the interface circuit 46 of the type known in the art of communicating by letter with motor controller 48, pressure transducer 30, air bubble sensor 32 and flow transducer 33 operation of syringe pump 10.In addition, interface circuit 46 can receive the signal from keyboard 50, and this keyboard 50 allows user input data or order.In addition, interface circuit 46 can be to display 52 (for example liquid crystal type alphanumeric and/or pictorial displays) and/or speaker 54 output data.
Generally speaking, interface circuit 46 will be communicated by letter with processor 58 via inside bus structure 56.Processor 58 can read the user by keyboard 50 input or data 60 storage in electronic memory 59, and can carry out the program 62 (it also is stored in electronic memory 59) of storing to provide data according to conventionally known technology to display 52.
Referring now to Fig. 2, syringe pump 10 can provide the housing that for example supports above-mentioned various assembly and comprise carriage 61, and this carriage 61 holds the body of syringe 14.Carriage 61 provides the passage that generally is open upwards holding syringe 14 on the direction vertical with the axis 63 of syringe 14, thereby allows easily to install the new syringe 14 that loads in syringe pump 10.
Plunger piece 40 can provide the exterior section of engage pistons 18 plunger 18 is remained to slit 64 plunger piece 40, that be open upwards similarly, makes plunger 18 move together with plunger piece 40.Before drawing to be delivered to the patient from housing, IV pipe 24 can be attached to syringe 14 and the recess in carriage 61 in advance to hold by the upright side walls of flow transducer 33 and air bubble sensor 32 on pressure transducer 30.Lid 68 can adapt on air bubble sensor 32, pressure transducer 30 and flow transducer 33; avoid external disturbance to protect them; and IV pipe 24 is located and suitably remained in air bubble sensor 32, pressure transducer 30 and flow transducer 33, and provide support thing 79 for following pressure transducer 20.
Referring now to Fig. 3, pressure transducer 30 can be managed 24 wall 74 by IV and be measured pressure through the medicine 70 of IV pipe 24, to avoid the demand that is connected to separately the fluid contact pressure transducer and the problem of avoiding the sterilization of fluid contact pressure transducer.Cross the pipe sensor-based system such, spring-loaded plunger 72 can for example make the part distortion that keeps against supporter 79 of the wall 74 of IV pipe 24 under the known the spring biases strength from spring 76.The deflection of wall 74 can for example be measured by hall effect sensor 78, and this hall effect sensor 78 is positioned at place, opposite end spring 76 and plunger 72, and this plunger 72 has attached magnet 77.Hall effect sensor also can be positioned at other positions.This distortion can be managed 24 known features for IV and be proofreaied and correct.Can be based on the nearness of plunger 72 and magnet 77 and hall effect sensor 78, the increase distortion with wall 74 under the situation that material is known and the spring biases strength spring 76 is known of IV pipe 24 converts pressure reading to.Generally speaking, the pressure of medicine 70 is lower, and the distortion of wall 74 is larger with allowing, and the pressure of medicine 70 is higher, and the distortion of wall 74 is less with allowing.Alternative pressure capsule system can be used, and in this system, other sensor except hall effect sensor (comprising optical pickocff (photo optic sensor)) position monitoring can be used for.
Referring now to Fig. 4, air bubble sensor 32 can adopt relative ultrasonic transducer 80 and 82, and it transmits ultrasonic signal 84 through the medicine 70 in IV pipe 24.Appearance at the bubble 85 between transducer 80 and 82 will make the ultrasonic signal decay of transmitting between transducer 80 and 82, cause reducing at the signal intensity at receiving transducer 82 places, can be with this signal intensity with the threshold that arranges adjustablely with the bubble 85 of detection to sizing.
Flow transducer 33 can adopt for example following technology:
(1) ultrasound wave for example, is spent pipe supersonic Doppler or ultrasound wave delivery time and is measured and support circuit.
(2) infrared, for example, the IR light of infrared (IR) emitter emission, IR detector and support circuit.
(3) turbine or paddle wheel etc.
(4) based on the flow transducer of laser with support circuit.
(5) based on the flow transducer of hot flight time (thermal time of flight) with support circuit.
(6) based on the technology of differential pressure, for example two pressure transducers or a differential pressure pick-up such as the piezoresistive monolithic silicon pressure sensor.
Referring now to Fig. 5, in one embodiment, by carry out the measurement that twice pressure measxurement make (avoid equally to the demand that is connected to separately the fluid contact flow transducer and the problem of avoiding the sterilization of fluid contact pressure transducer) in wall 74 outsides of IV pipe, flow transducer 33 can be measured medicine 70 through the flow of IV pipe 24.In the top mode of describing about Fig. 3, the spring-loaded plunger 72a in upstream and the spring-loaded plunger 72b in downstream can make the separate section axial deformation that keeps against supporter 79 of the wall 74 of IV pipe 24 under known the spring biases strength of spring 76.As previously mentioned, the distortion of wall 74 can be for example by be positioned at spring 76 with its separately corresponding hall effect sensor 78a and the 78b at the place, opposite end of plunger 72 measure, each plunger 72 can have attached magnet 77.Signal from hall effect sensor 78a and 78b is sent to electronic controller 44, and the pressure differential between the measurement of carrying out for the known features of IV pipe 24 with by the hall effect sensor 78a that determines and 78b is proofreaied and correct.The indication of this pressure differential manage 24 pressure drop (parameter that will change according to flow) and thereby can be for the derivation flow by IV.Generally speaking, lower pressure differential will be indicated lower flow rate.This effect can be strengthened by the mild compression of the pipe of the IV between pressure transducer 24, and this mild compression is for example by providing the flow compression, protuberances 101 that give prominence to from supporter 79 between pressure transducer.What will appreciate that is, can use other method of the bending of determining the IV pipe, comprises condenser type or optical sensing.
Referring now to Fig. 6, in the alternative flow sensing of the aseptic covering that does not destroy IV pipe 24 is arranged, ultrasound transmitter device 102 and ultrasonic receiver 104 are located across IV pipe 24, so that the ultrasonic transmission path 106 through medicine 70 to be provided, this path is at least in part along the Axis Extension of IV pipe 24.The flow rate of medicine 70 can be processed and be used for deriving by electronic controller 44 to variation in ultrasonic transmission between ultrasonic transmitter 102 and ultrasonic receiver 104 such as transmission delay or Doppler frequency shift.
Referring now to Fig. 7, for example can by will manage 24 and the assembly supersonic welding of flow transducer 33 be connected together, to substitute flow transducer 33 and be integrated in IV pipe 24, and can sterilize to substituting flow transducer 33 before the direct contact problems that are used for solving between medicine 70 and sensor construction.Particularly, sensor construction can comprise inlet flow rate shaper 110a and the rate of discharge shaper 110b that aims at respectively on axis direction, and it produces controlled shaft to whirlpool in medicine 70.Between flow shaper 110 can be to rotate freely blade assembly 112 (wheeled turbine, wheel turbine), and its rotary speed will depend on that medicine is through the flow of IV pipe 24.This speed can derive from the outside by sensor 114, this sensor 114 such as optical pickocff, variable-reluctance transducer, hall effect sensor (supposing that magnet is on blade assembly 112) or capacitance type sensor etc., its sensing is in the situation that the variation of blade assembly 112 these parameters of rotation.The flow shaper favourable to spiral vane module 112 can be alternatively eliminated in this design.
Referring now to Fig. 8, the flow transducer 33 that substitutes also can be building up in IV pipe 24 to sterilize as a unit with IV pipe 24, and provide axially upper the first heat sensor 116a and the second heat sensor 116b separately, this the first heat sensor 116a and the second heat sensor 116b have electrical lead, the wall that these electrical leads pass IV pipe 24 hermetically is to be held by half of connector shell, and this connector shell allows the releasable electrical connection to electronic controller 44.According to known technology, one of heat sensor (for example heat sensor 116a) can heat by small electric current, and the difference between the temperature of heat sensor 116a and 116b is used for deriving flow rate.
Referring now to Fig. 9, optical-flow sensor 33 can provide optic sensor array 120, and this optic sensor array 120 can be surveyed medicine 70 in the mode of optics when medicine 70 process optical-flow sensor 33.This optic sensor array 120 can with the mobile pattern of the micro-optics inclusions in the mode detection of drugs 70 of optical mouse, be derived linear speed and thereby the derivation volume flow of medicine with the known diameter based on IV pipe 24.The array one of LED or laser technique and photodetector or the linear video camera of CCD can be used from this purpose.This concrete sensor can be managed 74 work of 24 wall by IV, and perhaps the accuracy in order to improve, can be integrated into this concrete sensor in IV pipe 24, perhaps can be as shown be integrated into the optical window 122 that IV manages in 24 and dock.Substantially instruct in US patent 6,664,948 for the exemplary circuit that realizes this optical array, by reference this patent is incorporated into this here, can modify that backlight or forward lighting systems are used for this purpose to it.
Referring now to Figure 10, in one embodiment, the patient end 34 of IV pipe 24 can alternatively provide the sensor that is positioned at close patient on IV pipe 24 or the sensor that is positioned at close patient on IV pipe 24 can additionally be provided.In this realization, sensor 86 not only can be measured the pressure of the variation of medicine 70, but also can measure or alternatively measure the fluctuation be coupled to the caused IV pipe of vascular system or its adapter by medicine 70 when the pressure oscillation that the heartbeat that sends to sensor 86 by liquid 75 by the patient causes in.Sensor 86 can be similar to the pressure transducer 30 that uses the plunger technology, perhaps can use piezoelectric transducer or MEMS (Micro-electromechanical Systems, MEMS) type accelerometer etc.Also can use other pressure sensing technologies.From the signal of sensor 86 can by extend along the outside of IV pipe 24 or be embedded in the thin wire 88 that IV arranges in tube wall and send, perhaps can wirelessly send etc.
Referring now to Fig. 1 and Figure 11, program 62 information from pressure transducer 30 and/or 86 of can being used to detects in the problem in patient's delivering medicament 70 by syringe pump 10, and the slow flow rate when namely usually being difficult to carry liquid 75 based on syringe pump 10 detects.Generally speaking, the problem in flow is caused by the variation of IV catheter pressure.For example, the detected pressure of pressure transducer 30 is increased in a certain amount and can indicates the obstruction that should be noted that IV pipe 24 when above.On the contrary, pressure drop can indicate IV pipe 24 to become disconnection or damaged when a certain amount is following.About pressure transducer 86, can obtain according to the loss of the dynamic heartbeat pressure signal that can be detected by sensor 86 alternative information that can indicate IV pipe 24 to disconnect.
Generally speaking, the operation of program 62 will allow the user by keyboard 50 input data, confirm by display 52 simultaneously.These data can comprise from expectation flow rate and the volume of the medicine 70 of syringe 14 conveyings.This data input processing is by processing block 90 indications.At ensuing processing block 92 places, usually after the activation command that processing block 90 users of place make, will activate motor 42 to produce flow rate and the volume of expectation according to processing block 92.
At Decision Block 100 places, can inquire air bubble sensor 32 checks in IV pipe 24 whether have bubble.If exist, program proceeds to processing block 98, alarm to be provided and to forbid further delivering medicament 70.
If there is no bubble, at Decision Block 94 places, inspection pressure sensor 30 and/or 86 pressure divergences with the disconnection, damage or the obstruction that determine whether to exist indication IV pipe 24.If such problem detected, program 62 proceeds to processing block 95, so that according to closed-loop fashion correcting motor driver, thereby pressure is entered in OK range.If successfully proofread and correct as indicated in Decision Block 96, program proceeds to processing block 98, activates pump and alarm is set stopping.Generally speaking, for example warning tones or the speech warning for providing by speaker 54 of alarm, this speech warning is provided by speech recognition technology well known in the art.The deexcitation to syringe pump 10 of with good grounds processing block 98 can be followed or be followed immediately to this alarm, thereby stop the conveying of medicine 70.
If the pressure divergence that does not detect at Decision Block 94 places, program proceeds to Decision Block 103, inquires that there flow transducer 33 is to check the flow rate that whether provides suitable.The determining and the standardization scope from the operation of the flow rate of deriving of flow transducer 33 and motor controller 48 can be compared of suitable flow rate.Generally speaking, when motor controller 48 inoperation, this scope is the away minor segment around zero delivery, and so that during motor 42 motion, change into the away minor segment around the flow that calculates based on the geometry of the operation of motor controller 48 and syringe 14 when activating motor controller 48.Can indicate the IV pipe to become with the patient higher than the flow of this scope disconnects.In this case, motor 48 will be with than the speed operation faster of its due speed, but may wrong (for example, owing to having used in this calculating than the less syringe diameter of actual injection device diameter) according to the internal calculation of electromotor velocity etc.Can indicate the obstruction in syringe 14 downstreams lower than the flow of this speed.In this case, motor will be with than the lower speed of its due speed operation and equally only may wrong (for example, using the syringe diameter larger than the actual size of syringe in calculating at this) according to the internal calculation of electromotor velocity etc.If flow rate is in this scope, program turns back to processing block 92 to complete syringe to the movement of expectation volume.Otherwise, program 62 proceeds to the processing block 95 and 96 for closed loop control as above, to adjust flow rate by adjusting electromotor velocity, and if not success may proceed to processing block 98 alarm to be provided and to forbid further delivering medicament 70.
Some term used herein only is used for the purpose of reference, thereby is not intended to limit.For example, such as " on ", term D score, " on " and " under " refers to the direction in the accompanying drawing of institute's reference.The text of describing the assembly of discussing by reference such as 'fornt', 'back', " rear portion ", " bottom " and the term description " sidepiece " and relevant drawings are known understand consistent but the part assembly direction in reference frame arbitrarily.Such term can comprise term, its derivative words and the similar foreign word that mask body is mentioned.Similarly, term " first ", " second " and refer to other such numerical value terms of structure and do not mean that order or the order, unless context is clearly pointed out.
When the element of introducing the disclosure and exemplary embodiment or feature, article " ", " one ", " being somebody's turn to do " and " described " are intended to represent to exist one or more such element or feature.Term " comprises ", " comprising " and " having " is intended to be included and represent except specifically note those can have additional element or feature.What will be further understood that is, unless specifically be designated execution sequence, otherwise method step described herein, processing and operation will not be construed as necessarily require they according to discuss or illustrated particular order is carried out.What also will appreciate that is to adopt step additional or that substitute.
" microprocessor " and " processor " or " this microprocessor " and quoting of " this processor " be can be understood as comprise can be separately and/or one or more microprocessor of communicating by letter in distributed environment, and thereby can be configured to come and other processor communication via wired or wireless communication, wherein such a or more processors can be configured to operate on the equipment that can control for one or more processor of similar or distinct device.And, unless otherwise noted, otherwise can comprise the readable and accessible memory component of one or more processor and/or assembly to quoting of memorizer, the inside of the equipment that this memory component and/or assembly can be controlled at processor, the equipment that can control at processor outside or can conduct interviews via wired or wireless network.
Particularly, the embodiment that the present invention is not limited to comprise here and diagram, claim should be understood to include the variations of those embodiment of elements combination in the scope that falls into following claim, the part that contains embodiment and different embodiment.Full content with all public publications described herein (comprising patent and non-patent public publication) all is incorporated herein by reference accordingly.

Claims (20)

1. syringe pump comprises:
Housing, described housing is suitable for keeping syringe, and described syringe keeps liquid medicine;
Motor driver, described motor driver is attached to the housing of the part with the plunger part that is suitable for keeping described syringe, making described plunger part move in the tube portion of described syringe according to the motor driver signal, thereby from the described medicine of described injector to inject;
Flow transducer, described flow transducer is contiguous with the drug flow from described syringe, to monitor described flow; And
Electronic controller, described electronic controller is communicated by letter with described flow transducer with described motor driver, to detect the flow mistake and stop activating or adjusting described motor driver when the flow mistake being detected.
2. syringe pump according to claim 1 further comprises: for the user's of described syringe pump alarm indicator, and wherein when the flow mistake being detected described electronic controller activate described alarm.
3. syringe pump according to claim 2, wherein said flow mistake are the outer flow rates of preset range.
4. syringe pump according to claim 3, wherein said electronic controller provides the pump speed order to described motor driver, and wherein preset range order changes according to pump speed.
5. syringe pump according to claim 4, wherein said flow transducer receive from described syringe by the IV pipe to the patient, to come work in the situation that do not pierce through described IV pipe by the IV pipe.
6. syringe pump according to claim 5, wherein said flow transducer is derived flow according to the pressure differential along described IV length of tube.
7. syringe pump according to claim 5, wherein said flow transducer changes to derive flow by the velocity of wave along the described liquid of process of the shaft centerline measurement of described pipe.
8. syringe pump according to claim 5, wherein said flow transducer utilizes at least one optical pickocff, and at least one in the variation of the variation of being out of shape by pipe or the mobile pattern of the micro-optics inclusions in described medicine derives flow.
9. syringe pump according to claim 4, wherein said flow transducer is integrated in the IV pipe, and described IV pipe is attached to described syringe and is communicated with the patient.
10. syringe pump according to claim 9, wherein said flow transducer is derived flow according to the conduction of heat of described medicine.
11. syringe pump according to claim 9, the mechanical wheel of wherein said flow transducer for rotating in described medicine in response to drug flux.
12. syringe pump according to claim 11, the wherein said rotation of taking turns can detect by at least one in the variation that detects the magnetic field, luminous energy and the electric capacity that are caused by the described rotation of taking turns.
13. syringe pump according to claim 1, wherein said electronic controller are further derived flow rate according to data and the pump motor order relevant with the geometry of described syringe.
14. syringe pump according to claim 1 further comprises pressure transducer, described pressure transducer is communicated by letter with described electronic controller and is indicated the pressure of described medicine in attaching to the IV conduit of described syringe.
15. syringe pump according to claim 14, wherein said pressure transducer are the assemblies of described flow transducer.
16. a syringe pump comprises:
Housing, described housing is suitable for keeping syringe, and described syringe keeps liquid medicine;
Motor driver, described motor driver is attached to the housing of the part with the plunger part that is suitable for keeping described syringe, so that described plunger part is moved in the tube portion of described syringe, thereby from the described medicine of described injector to inject;
Sensor, described sensor provide at the signal of confirming that is connected between described syringe and patient; And
Electronic controller, described electronic controller and described motor driver and described sensor communication are to detect described syringe and described patient's disconnection, to stop activating described motor driver when described disconnection being detected.
17. syringe pump according to claim 16, wherein said sensor are selected from least one the group that comprises in pressure transducer, piezoelectric transducer, accelerometer and MEMS sensor.
18. syringe pump according to claim 16, wherein said sensor localization is at the far-end away from the IV conduit of described syringe.
19. syringe pump according to claim 16, wherein said sensor is communicated by letter with described electronic controller by one in wired connection and wireless connections.
20. flow transducer that is used for the sensing drug flux, comprise optical system, described optical system can be positioned near the known inner chamber of diameter, in order to receive light from described inner chamber, with the flow rate of the mobile pattern of the micro-optics inclusions in the described medicine of identification and the described inner chamber of derivation process thus.
CN201210443695.1A 2011-10-27 2012-10-29 There is the syringe pump of the flow monitoring of improvement Active CN103120818B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161552300P 2011-10-27 2011-10-27
US61/552,300 2011-10-27

Publications (2)

Publication Number Publication Date
CN103120818A true CN103120818A (en) 2013-05-29
CN103120818B CN103120818B (en) 2016-12-21

Family

ID=48452081

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201210443695.1A Active CN103120818B (en) 2011-10-27 2012-10-29 There is the syringe pump of the flow monitoring of improvement

Country Status (1)

Country Link
CN (1) CN103120818B (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105031799A (en) * 2015-06-18 2015-11-11 王玉英 Catheter system for newborns and department of pediatrics
CN105616167A (en) * 2016-02-26 2016-06-01 杨冉 Enteral nutrition infusion and blood glucose control integrated machine and control method
CN109172128A (en) * 2018-09-28 2019-01-11 宜邻医疗科技(上海)有限公司 A kind of accurate injecting systems for cell and genomic medicine injection treatment
CN109771801A (en) * 2019-02-21 2019-05-21 于立刚 A kind of monitoring and therapeutic apparatus for draining and displacing cerebrospinal fluid and pressurizing
CN109843360A (en) * 2016-08-17 2019-06-04 尼莎·沙惠尼 Inject monitoring device and system
CN110805745A (en) * 2019-11-15 2020-02-18 昆山新联德五金机械设备有限公司 Flow monitoring formula five metals sleeve pipe
CN112222652A (en) * 2020-12-09 2021-01-15 沈阳奥迈德科技有限公司 Clamping mechanism and automatic coupling device
CN115445028A (en) * 2022-10-28 2022-12-09 吉林省人民医院 Automatic injection governing system

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040171983A1 (en) * 2003-02-24 2004-09-02 Integrated Sensing Systems, Inc. Fluid delivery system and sensing unit therefor
CN1662269A (en) * 2002-06-21 2005-08-31 巴克斯特国际公司 Fluid delivery system with closed-loop flow control and method
US20090138215A1 (en) * 2007-10-18 2009-05-28 Washington University In St. Louis Photoacoustic Doppler Flow Sensing and Imaging
CN201939809U (en) * 2010-12-29 2011-08-24 滨州职业学院 Syringe

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1662269A (en) * 2002-06-21 2005-08-31 巴克斯特国际公司 Fluid delivery system with closed-loop flow control and method
US20040171983A1 (en) * 2003-02-24 2004-09-02 Integrated Sensing Systems, Inc. Fluid delivery system and sensing unit therefor
US20090138215A1 (en) * 2007-10-18 2009-05-28 Washington University In St. Louis Photoacoustic Doppler Flow Sensing and Imaging
CN201939809U (en) * 2010-12-29 2011-08-24 滨州职业学院 Syringe

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105031799A (en) * 2015-06-18 2015-11-11 王玉英 Catheter system for newborns and department of pediatrics
CN105616167A (en) * 2016-02-26 2016-06-01 杨冉 Enteral nutrition infusion and blood glucose control integrated machine and control method
CN105616167B (en) * 2016-02-26 2018-05-25 杨冉 A kind of enteral nutrition infusion and glycemic control all-in-one machine and control method
CN109843360A (en) * 2016-08-17 2019-06-04 尼莎·沙惠尼 Inject monitoring device and system
US11752274B2 (en) 2016-08-17 2023-09-12 Sawhney Nisha Injection monitoring device and system
CN109172128A (en) * 2018-09-28 2019-01-11 宜邻医疗科技(上海)有限公司 A kind of accurate injecting systems for cell and genomic medicine injection treatment
CN109771801A (en) * 2019-02-21 2019-05-21 于立刚 A kind of monitoring and therapeutic apparatus for draining and displacing cerebrospinal fluid and pressurizing
CN110805745A (en) * 2019-11-15 2020-02-18 昆山新联德五金机械设备有限公司 Flow monitoring formula five metals sleeve pipe
CN112222652A (en) * 2020-12-09 2021-01-15 沈阳奥迈德科技有限公司 Clamping mechanism and automatic coupling device
CN112222652B (en) * 2020-12-09 2021-03-19 沈阳奥迈德科技有限公司 Clamping mechanism and automatic coupling device
CN115445028A (en) * 2022-10-28 2022-12-09 吉林省人民医院 Automatic injection governing system

Also Published As

Publication number Publication date
CN103120818B (en) 2016-12-21

Similar Documents

Publication Publication Date Title
US9375531B2 (en) Syringe pump with improved flow monitoring
CN103120818A (en) Injection pump possessing improved flow monitoring
US11554209B2 (en) Systems, apparatuses and methods for fluid infusion into a body
US7775127B2 (en) Method and system for measuring flow at patient utilizing differential force sensor
CN110621366B (en) Intelligent wearable injection and/or infusion device
JP7061463B2 (en) IV flow management system and method
KR101674839B1 (en) Method and apparatus for detection and management of air-in-line
US11273257B2 (en) Infusion pump system
WO2014049660A1 (en) Infusion pump
CN105848694B (en) Fluid control system and disposable assembly
US11097069B2 (en) Air in-line sensing system for IV infusion lines
JP2017536206A (en) Force sensing resistor for liquid low volume detection and occlusion detection, and method and apparatus for flow sensing along a fluid path in a fluid delivery device
US20220409051A1 (en) Device for delivering medication to a patient
JP2022084793A (en) Method for readying fluid sensor associated with medical device and method for readying fluid conduit associated with medical device
CN104225722A (en) Infusion device and infusion control method
CN110958894A (en) Accurate flow rate regulation of IV pumps
KR101854862B1 (en) Apparatus and system for adjusting ringer's fluid
US11191900B2 (en) Intravenous infusion system with real-time infusion rate monitoring and closed-loop infusion rate control
US20240009366A1 (en) System and Method for Pressure Sensor Based Gas Bubble Detection for a Drug Delivery Device
US20240082486A1 (en) Drug delivery device
KR102638062B1 (en) Method for delivering residual liquid within enteral or other infusion device
WO2013059136A1 (en) Air-in -line detector
CN115737982A (en) Ultrasonic infusion monitor
CN115364305A (en) Infusion pump system, infusion pump monitoring system and method

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant