CA2471186C - Accommodating lens assembly - Google Patents
Accommodating lens assembly Download PDFInfo
- Publication number
- CA2471186C CA2471186C CA002471186A CA2471186A CA2471186C CA 2471186 C CA2471186 C CA 2471186C CA 002471186 A CA002471186 A CA 002471186A CA 2471186 A CA2471186 A CA 2471186A CA 2471186 C CA2471186 C CA 2471186C
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- Canada
- Prior art keywords
- lens assembly
- haptics
- eye
- accommodating lens
- assembly according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- 230000003287 optical effect Effects 0.000 claims abstract description 12
- 239000002775 capsule Substances 0.000 claims description 18
- 239000011796 hollow space material Substances 0.000 claims description 12
- 229920001296 polysiloxane Polymers 0.000 claims description 12
- 238000002513 implantation Methods 0.000 claims description 11
- 238000004873 anchoring Methods 0.000 claims description 10
- 239000000463 material Substances 0.000 claims description 6
- 241000937413 Axia Species 0.000 abstract 1
- 210000004240 ciliary body Anatomy 0.000 description 13
- 239000012528 membrane Substances 0.000 description 6
- 239000000499 gel Substances 0.000 description 5
- 210000001525 retina Anatomy 0.000 description 5
- 208000002177 Cataract Diseases 0.000 description 4
- 210000003205 muscle Anatomy 0.000 description 4
- 238000001356 surgical procedure Methods 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- 230000008602 contraction Effects 0.000 description 3
- 230000001886 ciliary effect Effects 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 230000035945 sensitivity Effects 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 201000004569 Blindness Diseases 0.000 description 1
- 241000282412 Homo Species 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 230000004308 accommodation Effects 0.000 description 1
- 230000000712 assembly Effects 0.000 description 1
- 238000000429 assembly Methods 0.000 description 1
- 239000000560 biocompatible material Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000004438 eyesight Effects 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000000017 hydrogel Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000004118 muscle contraction Effects 0.000 description 1
- 230000003387 muscular Effects 0.000 description 1
- 230000012191 relaxation of muscle Effects 0.000 description 1
- 230000037390 scarring Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/16—Intraocular lenses
- A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
- A61F2/1624—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus having adjustable focus; power activated variable focus means, e.g. mechanically or electrically by the ciliary muscle or from the outside
- A61F2/1635—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus having adjustable focus; power activated variable focus means, e.g. mechanically or electrically by the ciliary muscle or from the outside for changing shape
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/16—Intraocular lenses
- A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
- A61F2/1648—Multipart lenses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/16—Intraocular lenses
- A61F2002/1681—Intraocular lenses having supporting structure for lens, e.g. haptics
- A61F2002/1689—Intraocular lenses having supporting structure for lens, e.g. haptics having plate-haptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2220/0008—Fixation appliances for connecting prostheses to the body
- A61F2220/0016—Fixation appliances for connecting prostheses to the body with sharp anchoring protrusions, e.g. barbs, pins, spikes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0065—Additional features; Implant or prostheses properties not otherwise provided for telescopic
Abstract
An accommodating lens assembly having an optical axis and being adapted to b e implanted in a posterior chamber of an eye having a capsular unit located therein. The assembly comprises a rigid haptics element adapted to secure th e assembly within the posterior chamber outside said capsular unit. The elemen t is transparent at least in a region around the axis. The assembly further comprises a resilient body adapted to operate as a lens having a curved surface when pressed up against the region of the haptics element by an axia l force applied thereto by the capsular unit. A change in this force causes a change in a radius of curvature for the curved surface.
Description
ACCOMMODATING LENS ASSEMBLY
FIELD OF THE INVENTION
This invention relates to intraocular lenses, and in particular, to accommodating intraocular lenses capable of focusing on objects located at various distances therefrom.
BACKGROUND OF THE INVENTION
The natural lens of a humain eye is a transparent crystalline body, which is contained within a capsular bag located behind the iris and in front of the vitreous cavity in a region known as the posterior chamber. The capsular bag is attached on all sides by fibers, called zonules, to a muscular ciliary body. At its rear, the vitreous cavity, which is filled with a gel, further includes the retina, on which light rays passing through the lens are focused. Contraction and relaxation of the ciliary bodies changes the shape of the bag and of the natural lens therein, thereby enabling the eye to focus light rays on the retina originating from objects at various distances.
Cataracts occur when the natural lens of the eye or of its surrounding transparent membrane becomes clouded and obstructs the passage of light resulting in various degrees of blindness. To correct this condition in a patient, a surgical procedure is known to be performed in which the clouded natural lens, or cataract, is extracted and replaced by an artificial intraocular lens. During cataract surgery, the anterior portion of the capsular bag is removed along with the cataract, and the posterior portion of the capsular bag, called the posterior capsule, is sometimes left intact to serve as a support site for implanting the intraocular lens. Such lenses, however, have the drawback that they have a fixed refractive power and are therefore unable to change their focus.
Various types of intraocular lenses having the capability of altering their refractive power have been suggested in an effort to duplicate the performance of the natural lens within the eye. Such accommodating intraocular lenses, as they are known in the art, have a variety of designs directed to enable the patient to focus on, and thereby clearly see, objects located at a plurality of distances.
Examples may be found in such publications as US 4,254,509, US 4,932,966, US 6,299,641, and US 6,406,494.
US 5,489,302 discloses an accommodating intraocular lens for implantation in the posterior chamber of the eye. This lens comprises a short tubular rigid frame and transparent and resilient membrane attached thereto at its bases. The frame and the membranes confine a sealed space filled with a gas. The frame includes flexible regions attached via haptics to the posterior capsule. Upon stretching of the capsule by the eye's ciliary muscles, the flexible regions are pulled apart, thereby increasing the volume and decreasing the pressure within the sealed space. This changes the curvature of the membranes and accordingly, the refractive power of the lens.
US 6,117,171 discloses an accommodating intraocular lens which is contained inside an encapsulating rigid shell so as to make it substantially insensitive to changes in the intraocular environment. The lens is adapted to be implanted within the posterior capsule and comprises a flexible transparent membrane, which divides the interior of the intraocular lens into separate front and rear spaces, each filled with a fluid having a different refractive index. The periphery of the rear space is attached to haptics, which are in turn attached to the posterior capsule. Upon stretching of the capsule by the eye's ciliary muscles, the haptics and hence this periphery is twisted apart to increase the volume of rear space and changes the pressure difference between the spaces. As a result, the curvature of the membrane and accordingly, the refractive power of the lens changes.
FIELD OF THE INVENTION
This invention relates to intraocular lenses, and in particular, to accommodating intraocular lenses capable of focusing on objects located at various distances therefrom.
BACKGROUND OF THE INVENTION
The natural lens of a humain eye is a transparent crystalline body, which is contained within a capsular bag located behind the iris and in front of the vitreous cavity in a region known as the posterior chamber. The capsular bag is attached on all sides by fibers, called zonules, to a muscular ciliary body. At its rear, the vitreous cavity, which is filled with a gel, further includes the retina, on which light rays passing through the lens are focused. Contraction and relaxation of the ciliary bodies changes the shape of the bag and of the natural lens therein, thereby enabling the eye to focus light rays on the retina originating from objects at various distances.
Cataracts occur when the natural lens of the eye or of its surrounding transparent membrane becomes clouded and obstructs the passage of light resulting in various degrees of blindness. To correct this condition in a patient, a surgical procedure is known to be performed in which the clouded natural lens, or cataract, is extracted and replaced by an artificial intraocular lens. During cataract surgery, the anterior portion of the capsular bag is removed along with the cataract, and the posterior portion of the capsular bag, called the posterior capsule, is sometimes left intact to serve as a support site for implanting the intraocular lens. Such lenses, however, have the drawback that they have a fixed refractive power and are therefore unable to change their focus.
Various types of intraocular lenses having the capability of altering their refractive power have been suggested in an effort to duplicate the performance of the natural lens within the eye. Such accommodating intraocular lenses, as they are known in the art, have a variety of designs directed to enable the patient to focus on, and thereby clearly see, objects located at a plurality of distances.
Examples may be found in such publications as US 4,254,509, US 4,932,966, US 6,299,641, and US 6,406,494.
US 5,489,302 discloses an accommodating intraocular lens for implantation in the posterior chamber of the eye. This lens comprises a short tubular rigid frame and transparent and resilient membrane attached thereto at its bases. The frame and the membranes confine a sealed space filled with a gas. The frame includes flexible regions attached via haptics to the posterior capsule. Upon stretching of the capsule by the eye's ciliary muscles, the flexible regions are pulled apart, thereby increasing the volume and decreasing the pressure within the sealed space. This changes the curvature of the membranes and accordingly, the refractive power of the lens.
US 6,117,171 discloses an accommodating intraocular lens which is contained inside an encapsulating rigid shell so as to make it substantially insensitive to changes in the intraocular environment. The lens is adapted to be implanted within the posterior capsule and comprises a flexible transparent membrane, which divides the interior of the intraocular lens into separate front and rear spaces, each filled with a fluid having a different refractive index. The periphery of the rear space is attached to haptics, which are in turn attached to the posterior capsule. Upon stretching of the capsule by the eye's ciliary muscles, the haptics and hence this periphery is twisted apart to increase the volume of rear space and changes the pressure difference between the spaces. As a result, the curvature of the membrane and accordingly, the refractive power of the lens changes.
SUMMARY OF THE INVENTION
The present invention suggests an accommodating lens assembly having an optical axis and being adapted to be implanted in a posterior chamber of an eye having a capsular unit located therein. The assembly comprises a rigid haptics element adapted to secure said assembly within said posterior chamber outside said capsular unit, the element being transparent at least in a region around said axis.
The assembly further comprises a resilient body adapted to operate as a lens with a radius of curvature, when pressed up against said region of the rigid element by an axial force applied thereto by said capsular unit, whereby a change in said force causes a change in said radius of curvature.
The term "capsular unit", as it is used in the present description and Claims, refers to the posterior capsule, the zonules, and the ciliary body, which are interconnected and act in unison, forming in accordance with the present invention, a kind of cable whose varying tension provides the axial force applied to and utilized by the lens assembly of the present invention to achieve accommodation.
The assembly of the present invention is directed to substitute for a natural lens after its removal from the eye, not only by enabling the eye to see after implantation of the assembly, but also by enabling it to accommodate and thereby bring into focus objects located at a continuum of distances. In order to achieve the latter, the assembly is designed to be fixed in the posterior chamber, with the resilient body axially abutting the posterior capsule. The resilient body may be attached to the haptic element or may simply be held in place up against the element by the tension of the capsular unit.
The lens assembly of the present invention utilizes the natural compression and relaxation of the capsular unit to impart an axial force on the resilient body in order to cause it to act as a lens whose radius of curvature, and therefore the refractive power it provides, varies depending on the magnitude of the force.
In this way, the lens assembly cooperates with the natural operation of the eye to accommodate and enable the eye to clearly see objects at different distances.
The present invention suggests an accommodating lens assembly having an optical axis and being adapted to be implanted in a posterior chamber of an eye having a capsular unit located therein. The assembly comprises a rigid haptics element adapted to secure said assembly within said posterior chamber outside said capsular unit, the element being transparent at least in a region around said axis.
The assembly further comprises a resilient body adapted to operate as a lens with a radius of curvature, when pressed up against said region of the rigid element by an axial force applied thereto by said capsular unit, whereby a change in said force causes a change in said radius of curvature.
The term "capsular unit", as it is used in the present description and Claims, refers to the posterior capsule, the zonules, and the ciliary body, which are interconnected and act in unison, forming in accordance with the present invention, a kind of cable whose varying tension provides the axial force applied to and utilized by the lens assembly of the present invention to achieve accommodation.
The assembly of the present invention is directed to substitute for a natural lens after its removal from the eye, not only by enabling the eye to see after implantation of the assembly, but also by enabling it to accommodate and thereby bring into focus objects located at a continuum of distances. In order to achieve the latter, the assembly is designed to be fixed in the posterior chamber, with the resilient body axially abutting the posterior capsule. The resilient body may be attached to the haptic element or may simply be held in place up against the element by the tension of the capsular unit.
The lens assembly of the present invention utilizes the natural compression and relaxation of the capsular unit to impart an axial force on the resilient body in order to cause it to act as a lens whose radius of curvature, and therefore the refractive power it provides, varies depending on the magnitude of the force.
In this way, the lens assembly cooperates with the natural operation of the eye to accommodate and enable the eye to clearly see objects at different distances.
The haptics element of the assembly according to the present invention may adopt any of a variety of designs known in the art, e.g. it may be curved or it may be in the form of a plate, which spans a plane essentially perpendicular to the optical axis of the assembly. In addition to said region, the haptics element may be completely transparent. Said region of the element may be in the form of a transparent component, such as a clear panel or another lens which may have such a curvature and index of refraction as to enhance the accommodating capability of the lens assembly.
The haptics element may have a hollow space formed in its transparent lo region. This hollow space is adapted to allow said resilient body to bulge through said space in response to said force. This enables the lens assembly to provide a range of refractive power (i.e. the accommodating capability) depending on the bulge's radius of curvature, which is determined and may be varied by the magnitude of the force applied by the capsular unit.
The haptics element of the lens assembly of the present invention is adapted to securely fix the assembly in front of the capsular unit in the posterior chamber of the eye. It is essential that the haptics element maintain a substantially immovable position. To this end, the haptics element is preferably adapted to be fixed to the scleral wall of the eye in two or more places in the regions between the iris and the ciliary body. To achieve the latter, the haptics element preferably comprise anchoring means, such as in the form of teeth. One example of such means is described in co-pending Israel patent application no. 141529.
Implantation of the lens assembly in accordance with the present invention may be achieved using equipment and techniques that are conventional and well known in the art. However, in order to facilitate the implantation and anchoring of the assembly in the eye, the haptics element of the assembly of the present invention preferably also includes at least one extendible member at its periphery.
For example, the haptics element in the form of a plate discussed above may have a telescoping end which is only extended after the assembly has been inserted into the eye and has been positioned at the anchoring site. This extendible member may also be provided with anchoring means attached thereto. The extendible member serves to keep the assembly small enough to insert into the eye until its securing is desired. The extendible member, such as the telescoping end, may be passive or may be spring biased being compressed to enable implantation and released to maintain anchoring by a resisting force.
The haptics element of the lens assembly in accordance with the present invention may be made of a variety of possible rigid materials suitable for invasive medical use and known in the art to be used in the formation of haptics.
The resilient body of the accommodating lens assembly in accordance with the present invention may be made of any suitable deformable material, such as silicone or hydrogel, having an index of refraction different from the gel within the eye. The resilient body must not necessarily be made of a single component or material. For example, the body may be in the form of a sac filled with a fluid or gel. However, in the case of such a sac, for example, it is essential the periphery of the body be made with a unitary material so that the fluctuating internal pressure of the eye does not affect the sac in an anisotropic manner, which would unpredictably affect the vision provided by the assembly.
The resilient body of the accommodating lens assembly in accordance with the present invention may have a variety of shapes so long as the shape has or is able to achieve a radius of curvature and thereby perform as a lens. For example, in the case when the haptics element is curved and solid (i.e. is devoid of a hollow space in said region), the resilient body may have such shapes as a sphere which, when pressed against its haptics element, takes on the shape of a double convex lens. Also, if the haptics element is flat like a plate, for example, the planar side of a hemispherical resilient body may be pressed up against it to act as a plano-convex lens. As another example, if the haptics element is flat and comprises a hollow space, such as an aperture or a cavity, the resilient body having a bi-planar shape, such as that of a solid circular disc, may be pressed up against the element since the force applied by the capsular unit will cause it to bulge into the aperture or cavity and attain, thereby, a radius of curvature.
The haptics element may have a hollow space formed in its transparent lo region. This hollow space is adapted to allow said resilient body to bulge through said space in response to said force. This enables the lens assembly to provide a range of refractive power (i.e. the accommodating capability) depending on the bulge's radius of curvature, which is determined and may be varied by the magnitude of the force applied by the capsular unit.
The haptics element of the lens assembly of the present invention is adapted to securely fix the assembly in front of the capsular unit in the posterior chamber of the eye. It is essential that the haptics element maintain a substantially immovable position. To this end, the haptics element is preferably adapted to be fixed to the scleral wall of the eye in two or more places in the regions between the iris and the ciliary body. To achieve the latter, the haptics element preferably comprise anchoring means, such as in the form of teeth. One example of such means is described in co-pending Israel patent application no. 141529.
Implantation of the lens assembly in accordance with the present invention may be achieved using equipment and techniques that are conventional and well known in the art. However, in order to facilitate the implantation and anchoring of the assembly in the eye, the haptics element of the assembly of the present invention preferably also includes at least one extendible member at its periphery.
For example, the haptics element in the form of a plate discussed above may have a telescoping end which is only extended after the assembly has been inserted into the eye and has been positioned at the anchoring site. This extendible member may also be provided with anchoring means attached thereto. The extendible member serves to keep the assembly small enough to insert into the eye until its securing is desired. The extendible member, such as the telescoping end, may be passive or may be spring biased being compressed to enable implantation and released to maintain anchoring by a resisting force.
The haptics element of the lens assembly in accordance with the present invention may be made of a variety of possible rigid materials suitable for invasive medical use and known in the art to be used in the formation of haptics.
The resilient body of the accommodating lens assembly in accordance with the present invention may be made of any suitable deformable material, such as silicone or hydrogel, having an index of refraction different from the gel within the eye. The resilient body must not necessarily be made of a single component or material. For example, the body may be in the form of a sac filled with a fluid or gel. However, in the case of such a sac, for example, it is essential the periphery of the body be made with a unitary material so that the fluctuating internal pressure of the eye does not affect the sac in an anisotropic manner, which would unpredictably affect the vision provided by the assembly.
The resilient body of the accommodating lens assembly in accordance with the present invention may have a variety of shapes so long as the shape has or is able to achieve a radius of curvature and thereby perform as a lens. For example, in the case when the haptics element is curved and solid (i.e. is devoid of a hollow space in said region), the resilient body may have such shapes as a sphere which, when pressed against its haptics element, takes on the shape of a double convex lens. Also, if the haptics element is flat like a plate, for example, the planar side of a hemispherical resilient body may be pressed up against it to act as a plano-convex lens. As another example, if the haptics element is flat and comprises a hollow space, such as an aperture or a cavity, the resilient body having a bi-planar shape, such as that of a solid circular disc, may be pressed up against the element since the force applied by the capsular unit will cause it to bulge into the aperture or cavity and attain, thereby, a radius of curvature.
The accommodating lens assembly in accordance with the present invention may further comprise a rigid piston member, which sandwiches said resilient body between it and said haptics element, and which is designed to be pushed by said force and, in response, to cause said resilient body to take on a desired curved shape. The piston member is transparent at least in a region around said axis and is movable along said axis with respect to said element. One or both of said haptics element and said piston member have a hollow space in their transparent region to allow said resilient body to bulge through said space in response to said force.
The hollow spaces formed in the haptics element and/or the piston member in preferred embodiments of the lens assembly in accordance with the present invention, may have various designs such as circular blind or through holes.
Preferable, these spaces are large enough that their periphery is far from the optical axis so as not to substantially affect light passing thereabout by causing diffraction and other such undesired optical effects. Also, in order to minimize such optical disturbances, if a hollow space is formed within the piston member, the haptics element may be devoid of such a space and vice versa.
The piston member of the accommodating lens assembly of the present invention may be made of any of a variety of rigid biocompatible materials.
The piston member may also have any of a variety of designs, such as a plano-convex design with the convexly curved side abutting the capsular unit so as to contribute to the range of refractive power which may be achieve by the assembly.
Clearly, in the latter case, the transparent region of the piston member, like the resilient body, must have an index of refraction different from the natural gel surrounding the assembly when implanted in the eye. The radius of curvature and the index of refraction of the piston member may be adjusted and chosen in numerous ways to arrive at lens assemblies having various ranges of refractive power and degrees of sensitivity to the force applied by the capsular unit.
The advantages provided by the accommodating lens assembly of the present invention abound, particularly because of it is designed to be positioned in the eye completely outside of the posterior capsule. One advantage, for example, is that the lens assembly does not undesirably stretch and consequently harm the capsule. Also, the lens assembly does not need to conform to the size or shape of the capsule, and is therefore free to take on a larger variety of designs.
Furthermore, the capsule is sometimes damaged during the surgery to remove the natural lens, but the lens assembly of the present invention does not require that the capsule be completely intact in the form of a bag but merely that it remain reliably connected as part of the capsular unit. Another advantage arising from the lens assembly being positioned outside of the posterior capsule is that it remains unaffected by the lo permanent and unpredictable constriction that the capsule inevitably undergoes due to scarring following the surgery for removal of the natural lens.
In addition to the above, the lens assembly of the present invention offers advantages such as a simple and inexpensive construction. The lens assembly of the present invention also provides the ability to accommodate within a vast range of refractive power, including the full range provided by the natural eye. Also, the lens assembly provides means for varying its sensitivity in response to the force applied by the capsular unit.
BRIEF DESCRIPTION OF THE DRAWINGS
In order to understand the invention and to see how it may be carried out in practice, a preferred embodiment will now be described, by way of non-limiting example only, with reference to the accompanying drawings, in which:
Fig. lA is a plan view of an accommodating lens assembly in accordance with the present invention;
Fig. 1B is a side view of the accommodating lens assembly shown in Fig.
lA;
Fig. 2A shows the accommodating lens assembly of Figs. lA and IB as implanted in an eye;
Fig. 2B shows the accommodating lens assembly of Figs. 1A and 1B in operation after it has been implanted in an eye as in Fig. 2A;
The hollow spaces formed in the haptics element and/or the piston member in preferred embodiments of the lens assembly in accordance with the present invention, may have various designs such as circular blind or through holes.
Preferable, these spaces are large enough that their periphery is far from the optical axis so as not to substantially affect light passing thereabout by causing diffraction and other such undesired optical effects. Also, in order to minimize such optical disturbances, if a hollow space is formed within the piston member, the haptics element may be devoid of such a space and vice versa.
The piston member of the accommodating lens assembly of the present invention may be made of any of a variety of rigid biocompatible materials.
The piston member may also have any of a variety of designs, such as a plano-convex design with the convexly curved side abutting the capsular unit so as to contribute to the range of refractive power which may be achieve by the assembly.
Clearly, in the latter case, the transparent region of the piston member, like the resilient body, must have an index of refraction different from the natural gel surrounding the assembly when implanted in the eye. The radius of curvature and the index of refraction of the piston member may be adjusted and chosen in numerous ways to arrive at lens assemblies having various ranges of refractive power and degrees of sensitivity to the force applied by the capsular unit.
The advantages provided by the accommodating lens assembly of the present invention abound, particularly because of it is designed to be positioned in the eye completely outside of the posterior capsule. One advantage, for example, is that the lens assembly does not undesirably stretch and consequently harm the capsule. Also, the lens assembly does not need to conform to the size or shape of the capsule, and is therefore free to take on a larger variety of designs.
Furthermore, the capsule is sometimes damaged during the surgery to remove the natural lens, but the lens assembly of the present invention does not require that the capsule be completely intact in the form of a bag but merely that it remain reliably connected as part of the capsular unit. Another advantage arising from the lens assembly being positioned outside of the posterior capsule is that it remains unaffected by the lo permanent and unpredictable constriction that the capsule inevitably undergoes due to scarring following the surgery for removal of the natural lens.
In addition to the above, the lens assembly of the present invention offers advantages such as a simple and inexpensive construction. The lens assembly of the present invention also provides the ability to accommodate within a vast range of refractive power, including the full range provided by the natural eye. Also, the lens assembly provides means for varying its sensitivity in response to the force applied by the capsular unit.
BRIEF DESCRIPTION OF THE DRAWINGS
In order to understand the invention and to see how it may be carried out in practice, a preferred embodiment will now be described, by way of non-limiting example only, with reference to the accompanying drawings, in which:
Fig. lA is a plan view of an accommodating lens assembly in accordance with the present invention;
Fig. 1B is a side view of the accommodating lens assembly shown in Fig.
lA;
Fig. 2A shows the accommodating lens assembly of Figs. lA and IB as implanted in an eye;
Fig. 2B shows the accommodating lens assembly of Figs. 1A and 1B in operation after it has been implanted in an eye as in Fig. 2A;
Fig. 3A is a plan view of another embodiment of an acconunodating lens assembly in accordance with the present invention;
Fig. 3B is a side view of the accommodating lens assembly shown in Fig.
3A;
Fig. 4A shows the accommodating lens assembly of Figs. 3A and 3B as implanted in an eye;
Fig. 4B shows the accommodating lens assembly of Figs. 3A and 3B in operation after it has been implanted in an eye as in Fig. 4A;
Fig. 5A shows yet another embodiment of an accommodating lens assembly t o in accordance with the present invention as implanted in the eye;
Fig. 5B shows the accommodating lens assembly of Figs. 5A in operation in the eye.
DETAILED DESCRIPTION OF THE INVENTION
The subsequent description and figures refer to different examples of an accommodating lens assembly of the present invention and its functional position as implanted in a human eye E. As shown in Figs. 2A, 2B, 4A, 4B, 5A, and 5B, the eye E, which is filled with natural gel (not shown) having an index of refraction of about 1.3, comprises a scleral wall S, an iris, and a retina R (not shown).
The eye E
further includes a ciliary body CB, from which extend zonules Z connected to a posterior capsule PC. These last three parts of the eye E constitute the capsular unit 1.
One example of an accommodating lens assembly in accordance with the present invention adapted for implantation within the eye E is shown in Fig.
lA in plan view and in Fig. 1B from a side view. The accommodating lens assembly 2 has an optical axis A-A and comprises a rigid haptics plate 4 having a first lens 6 made of a rigid material having an index of refraction higher than that of water. The plate 4 further includes a telescoping haptics member 8, which is slidably biased in grooves 8a so as to be extendible in a plane perpendicular to the optical axis A-A.
Fig. 3B is a side view of the accommodating lens assembly shown in Fig.
3A;
Fig. 4A shows the accommodating lens assembly of Figs. 3A and 3B as implanted in an eye;
Fig. 4B shows the accommodating lens assembly of Figs. 3A and 3B in operation after it has been implanted in an eye as in Fig. 4A;
Fig. 5A shows yet another embodiment of an accommodating lens assembly t o in accordance with the present invention as implanted in the eye;
Fig. 5B shows the accommodating lens assembly of Figs. 5A in operation in the eye.
DETAILED DESCRIPTION OF THE INVENTION
The subsequent description and figures refer to different examples of an accommodating lens assembly of the present invention and its functional position as implanted in a human eye E. As shown in Figs. 2A, 2B, 4A, 4B, 5A, and 5B, the eye E, which is filled with natural gel (not shown) having an index of refraction of about 1.3, comprises a scleral wall S, an iris, and a retina R (not shown).
The eye E
further includes a ciliary body CB, from which extend zonules Z connected to a posterior capsule PC. These last three parts of the eye E constitute the capsular unit 1.
One example of an accommodating lens assembly in accordance with the present invention adapted for implantation within the eye E is shown in Fig.
lA in plan view and in Fig. 1B from a side view. The accommodating lens assembly 2 has an optical axis A-A and comprises a rigid haptics plate 4 having a first lens 6 made of a rigid material having an index of refraction higher than that of water. The plate 4 further includes a telescoping haptics member 8, which is slidably biased in grooves 8a so as to be extendible in a plane perpendicular to the optical axis A-A.
The plate 4 and the telescoping member 8 have teeth 9 projecting therefrom for anchoring the first lens assembly 2 within the eye E.
The lens assembly 2 further comprises a silicone ball 10 attached to the plate so as to be located on the axis A-A. The silicone ball 10 also has an index of refraction higher than that of water.
As is shown in Figs. 2A and 2B, the haptics plate 4 of the assembly 2 is anchored, using the teeth 9, to the eye's scleral wall S at two locations between the ciliary body CB and the iris I. The anchoring is done by first inserting the teeth 9 on the plate 4 to the desired point in the scleral wall S, and then extending the telescoping member 8 until its teeth 9 enter the opposing side of the scleral wall S.
The silicone ball 10 directly contacts the capsular unit 1, which is stretched around the ball 10 and transforms it into a second plano-convex lens 10' as shown in Fig. 2A
with a radius of curvature R1.
In operation, upon contraction and relaxation by muscles of the ciliary body CB, tension in the capsular unit 1 will change and a variable force proportional to the tension will be applied to the silicone ball 10 along axis A-A. Fig. 2B shows an increase in tension in the capsular unit 1 compared to Fig. 2A upon relaxation of the ciliary body CB. The increase in tension applies a forward force along the axis in the direction of the iris I. This force causes the lens 10' to further deform and increase its radius of curvature from R1 to R2. This increase in radius will enable the eye E to focus on far objects by adjusting the assembly's focal plane until it resides on the retina. Clearly, the reverse may be done in which the ciliary body contracts, reducing the radius to focus on objects at nearer distances from the eye E.
Another example of an accommodating lens assembly 22 for implantation within a human eye E in accordance with the present invention is shown in a preferred embodiment in Fig. 3A in plan view and in Fig. 3B from a side view.
The accommodating lens assembly 22 has an optical axis B-B and comprises a rigid haptics plate 24, similar to that included in the lens assembly 2, and having a circular aperture 26. The plate 24 further includes a telescoping member 28, which is slidably biased in grooves 28a so as to be extendible. The plate 24 and the telescoping member 28 have teeth 29 projecting therefrom for anchoring the lens assembly 22 within the eye. The plate further includes a hollow, central cylindrical tube portion T extending around axis B-B. The tube portion T is concentric with the aperture 26 but has about double the diameter.
The accommodating lens assembly 22 further comprises a silicone disc 30 received within the tube portion T so as to occupy only a part of its axial dimension. The disc 30 has an index of refraction higher than that of water.
The lens assembly 22 also includes a rigid, plano-convex lens 31 having a to diameter slightly smaller than that of the tube portion T but greater than that of the aperture 26. The lens 31, which is designed to function like a piston by transferring an applied force to the disc 30, is received within the tube portion T to fill the space left unoccupied by the disc 30 and to press, with its planar face, the disc 30 up against the plate 24. The plano-convex lens 31 has a fixed radius of curvature and an index of refraction higher than that of water.
Figs. 4A and 4B show the haptics plate 24 of the assembly 22 anchored, using the teeth 29, to the eye's scleral wall S at two locations, each being between the ciliary body CB and the iris I. The silicone disc 30 is sandwiched between the haptics plate 24 and the lens 31, which directly contacts the capsular unit 1 with its convex side.
In operation, upon contraction and relaxation by muscles of the ciliary body CB, tension in the capsular unit 1 will change and apply a force to the lens 31 along axis B-B. Fig. 4B shows an increase in tension in the capsular unit 1 compared to Fig. 4A, which occurs upon relaxation of the ciliary body CB. This increase in tension applies a forward force on the lens 31 along the axis in the direction of the iris I. The applied force pushes the lens 31, which functions like a piston and presses, in turn, on the silicone disc 30, causing it to protrude from the aperture 26 in the form of a bulge 35 having a radius of curvature depending on the force.
The bulge 35 serves to add to the refractive power afforded by the convex curvature of lens 31. In this way, using the lens assembly 22, the eye E is given the ability to focus on nearer objects by changing the magnitude of the applied force and hence the radius of the bulge 35 until the object is focused on the retina R.
Yet another example of a lens assembly 42 in accordance with the present invention for implantation into the eye E is shown in a preferred embodiment in Figs. 5A and 5B. The lens assembly 42 is similar to the lens assembly 2in that it comprises a haptics plate 44 with an aperture 45, which is occupied by a rigid lens 46, similarly to lens 6 in Fig. 1A. Furthermore, the lens assembly 42 comprises a piston member 51. However, the piston member 51 has a cylindrical cavity 52 formed therein, into which the silicone disc 50 is adapted to bulge. The member 51 to is adapted transfer an axial force applied by the capsular unit 1 to silicone disc 50 sandwiched between the member 51 and the plate 44. In this way, the piston member 51 is similar to plano-convex lens 31 shown e.g. in Fig. 4A, but differs in that it does not have the additional ability to operate as a lens.
In operation, the piston member 51 of the lens assembly 42 transfers the ts axial force, created thereon by changes of tension in the capsular unit 1, to the silicone disc 50, causing it to form a bulge 54, which protrudes back into the cavity 52. The bulge 54 has a radius of curvature whose value varies depending on the magnitude of the force. As in the previously described embodiment, the bulge serves to provide the assembly 42 with a refractive power, whose magnitude can be 20 varied by the force applied by the capsular unit 1 and controlled by the contraction and relaxation of muscles in the eye's ciliary body CB.
It should be understood that the above described embodiments constitute only examples of an accommodating lens assembly for implantation into the eye according to the present invention, and that the scope of the present invention fully 25 encompasses other embodiments which may become obvious to those skilled in the art. For example, while implantation of the lens assembly in humans is described, the assembly may clearly also be applicable to other animals. Clearly, any and all possible permutations and/or combinations of different features as described above are within the scope of the present invention.
The lens assembly 2 further comprises a silicone ball 10 attached to the plate so as to be located on the axis A-A. The silicone ball 10 also has an index of refraction higher than that of water.
As is shown in Figs. 2A and 2B, the haptics plate 4 of the assembly 2 is anchored, using the teeth 9, to the eye's scleral wall S at two locations between the ciliary body CB and the iris I. The anchoring is done by first inserting the teeth 9 on the plate 4 to the desired point in the scleral wall S, and then extending the telescoping member 8 until its teeth 9 enter the opposing side of the scleral wall S.
The silicone ball 10 directly contacts the capsular unit 1, which is stretched around the ball 10 and transforms it into a second plano-convex lens 10' as shown in Fig. 2A
with a radius of curvature R1.
In operation, upon contraction and relaxation by muscles of the ciliary body CB, tension in the capsular unit 1 will change and a variable force proportional to the tension will be applied to the silicone ball 10 along axis A-A. Fig. 2B shows an increase in tension in the capsular unit 1 compared to Fig. 2A upon relaxation of the ciliary body CB. The increase in tension applies a forward force along the axis in the direction of the iris I. This force causes the lens 10' to further deform and increase its radius of curvature from R1 to R2. This increase in radius will enable the eye E to focus on far objects by adjusting the assembly's focal plane until it resides on the retina. Clearly, the reverse may be done in which the ciliary body contracts, reducing the radius to focus on objects at nearer distances from the eye E.
Another example of an accommodating lens assembly 22 for implantation within a human eye E in accordance with the present invention is shown in a preferred embodiment in Fig. 3A in plan view and in Fig. 3B from a side view.
The accommodating lens assembly 22 has an optical axis B-B and comprises a rigid haptics plate 24, similar to that included in the lens assembly 2, and having a circular aperture 26. The plate 24 further includes a telescoping member 28, which is slidably biased in grooves 28a so as to be extendible. The plate 24 and the telescoping member 28 have teeth 29 projecting therefrom for anchoring the lens assembly 22 within the eye. The plate further includes a hollow, central cylindrical tube portion T extending around axis B-B. The tube portion T is concentric with the aperture 26 but has about double the diameter.
The accommodating lens assembly 22 further comprises a silicone disc 30 received within the tube portion T so as to occupy only a part of its axial dimension. The disc 30 has an index of refraction higher than that of water.
The lens assembly 22 also includes a rigid, plano-convex lens 31 having a to diameter slightly smaller than that of the tube portion T but greater than that of the aperture 26. The lens 31, which is designed to function like a piston by transferring an applied force to the disc 30, is received within the tube portion T to fill the space left unoccupied by the disc 30 and to press, with its planar face, the disc 30 up against the plate 24. The plano-convex lens 31 has a fixed radius of curvature and an index of refraction higher than that of water.
Figs. 4A and 4B show the haptics plate 24 of the assembly 22 anchored, using the teeth 29, to the eye's scleral wall S at two locations, each being between the ciliary body CB and the iris I. The silicone disc 30 is sandwiched between the haptics plate 24 and the lens 31, which directly contacts the capsular unit 1 with its convex side.
In operation, upon contraction and relaxation by muscles of the ciliary body CB, tension in the capsular unit 1 will change and apply a force to the lens 31 along axis B-B. Fig. 4B shows an increase in tension in the capsular unit 1 compared to Fig. 4A, which occurs upon relaxation of the ciliary body CB. This increase in tension applies a forward force on the lens 31 along the axis in the direction of the iris I. The applied force pushes the lens 31, which functions like a piston and presses, in turn, on the silicone disc 30, causing it to protrude from the aperture 26 in the form of a bulge 35 having a radius of curvature depending on the force.
The bulge 35 serves to add to the refractive power afforded by the convex curvature of lens 31. In this way, using the lens assembly 22, the eye E is given the ability to focus on nearer objects by changing the magnitude of the applied force and hence the radius of the bulge 35 until the object is focused on the retina R.
Yet another example of a lens assembly 42 in accordance with the present invention for implantation into the eye E is shown in a preferred embodiment in Figs. 5A and 5B. The lens assembly 42 is similar to the lens assembly 2in that it comprises a haptics plate 44 with an aperture 45, which is occupied by a rigid lens 46, similarly to lens 6 in Fig. 1A. Furthermore, the lens assembly 42 comprises a piston member 51. However, the piston member 51 has a cylindrical cavity 52 formed therein, into which the silicone disc 50 is adapted to bulge. The member 51 to is adapted transfer an axial force applied by the capsular unit 1 to silicone disc 50 sandwiched between the member 51 and the plate 44. In this way, the piston member 51 is similar to plano-convex lens 31 shown e.g. in Fig. 4A, but differs in that it does not have the additional ability to operate as a lens.
In operation, the piston member 51 of the lens assembly 42 transfers the ts axial force, created thereon by changes of tension in the capsular unit 1, to the silicone disc 50, causing it to form a bulge 54, which protrudes back into the cavity 52. The bulge 54 has a radius of curvature whose value varies depending on the magnitude of the force. As in the previously described embodiment, the bulge serves to provide the assembly 42 with a refractive power, whose magnitude can be 20 varied by the force applied by the capsular unit 1 and controlled by the contraction and relaxation of muscles in the eye's ciliary body CB.
It should be understood that the above described embodiments constitute only examples of an accommodating lens assembly for implantation into the eye according to the present invention, and that the scope of the present invention fully 25 encompasses other embodiments which may become obvious to those skilled in the art. For example, while implantation of the lens assembly in humans is described, the assembly may clearly also be applicable to other animals. Clearly, any and all possible permutations and/or combinations of different features as described above are within the scope of the present invention.
Claims (12)
1. An accommodating lens assembly having an optical axis and being adapted to be implanted in a posterior chamber of an eye having a capsular unit located therein, the assembly comprising:
- a rigid haptics element adapted to secure said assembly within said posterior chamber outside said capsular unit, the element being transparent at least in a region around said axis;
- a resilient body adapted to operate as a lens having a curved surface when pressed up against said region of the haptics element by an axial force applied thereto by said capsular unit, whereby a change in said force causes a change in a radius of curvature for said curved surface.
- a rigid haptics element adapted to secure said assembly within said posterior chamber outside said capsular unit, the element being transparent at least in a region around said axis;
- a resilient body adapted to operate as a lens having a curved surface when pressed up against said region of the haptics element by an axial force applied thereto by said capsular unit, whereby a change in said force causes a change in a radius of curvature for said curved surface.
2. An accommodating lens assembly according to Claim 1, further comprising a rigid piston member, said resilient body being sandwiched between said piston member and said haptics element, the piston member being transparent at least in a region around said axis, and being movable along said axis with respect to said element by said force to cause said change in said radius of curvature.
3. An accommodating lens assembly according to Claim 1, wherein said haptics element has a hollow space formed in said region, the hollow space being adapted to allow said resilient body to bulge through said space in response to said force, to thereby provide said curved surface.
4. An accommodating lens assembly according to Claim 2, wherein said piston member has a hollow space formed in said region, the member being adapted to push said resilient body to bulge through said space in response to said force, to thereby provide said curved surface.
5. An accommodating lens assembly according to Claim 1, wherein the haptics element is in the form of a plate.
6. An accommodating lens assembly according to Claim 1, wherein said region of the haptics element is in the form of a lens.
7. An accommodating lens assembly according to Claim 3 or 4, wherein said hollow space is an aperture.
8. An accommodating lens assembly according to Claim 1, wherein the haptics element includes anchoring means adapted to anchor the assembly within the eye.
9. An accommodating lens assembly according to Claim 1, wherein the haptics element includes an extendible end for facilitating the implantation and anchoring of said assembly within the eye.
10. An accommodating lens assembly according to Claim 1, wherein the resilient body is made of silicone.
11. An accommodating lens assembly according to Claim 1, wherein the resilient body is in the form of a sac filled with a non-rigid material.
12. An accommodating lens assembly having an optical axis and being adapted to be implanted in a posterior chamber of an eye with an optical axis having a posterior capsule, the assembly comprising:
- a rigid haptics element adapted to secure said assembly within said posterior chamber outside the capsule, the element being transparent at least in a haptics element region around said axis;
- a rigid piston member transparent at least in a piston member region around said axis and mounted in the assembly so as to be movable along said axis with respect to the haptics element, at least one of said haptics element and said piston member having a hollow space in its transparent region;
a resilient body sandwiched between said element and said member, the body being adapted to protrude into said hollow space in the form of a bulge so as to operate as a lens with a curved surface upon the axial movement of said piston member.
- a rigid haptics element adapted to secure said assembly within said posterior chamber outside the capsule, the element being transparent at least in a haptics element region around said axis;
- a rigid piston member transparent at least in a piston member region around said axis and mounted in the assembly so as to be movable along said axis with respect to the haptics element, at least one of said haptics element and said piston member having a hollow space in its transparent region;
a resilient body sandwiched between said element and said member, the body being adapted to protrude into said hollow space in the form of a bulge so as to operate as a lens with a curved surface upon the axial movement of said piston member.
Applications Claiming Priority (3)
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IL14501501A IL145015A0 (en) | 2001-08-21 | 2001-08-21 | Accommodating lens |
IL145015 | 2001-08-21 | ||
PCT/IL2002/000693 WO2003015669A1 (en) | 2001-08-21 | 2002-08-21 | Accommodating lens assembly |
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CA2471186A1 CA2471186A1 (en) | 2003-02-27 |
CA2471186C true CA2471186C (en) | 2009-12-08 |
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CA002471186A Expired - Fee Related CA2471186C (en) | 2001-08-21 | 2002-08-21 | Accommodating lens assembly |
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US (4) | US7220279B2 (en) |
EP (1) | EP1420722B1 (en) |
AT (1) | ATE489916T1 (en) |
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Families Citing this family (125)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6468306B1 (en) | 1998-05-29 | 2002-10-22 | Advanced Medical Optics, Inc | IOL for inhibiting cell growth and reducing glare |
US20030060881A1 (en) | 1999-04-30 | 2003-03-27 | Advanced Medical Optics, Inc. | Intraocular lens combinations |
US20060238702A1 (en) | 1999-04-30 | 2006-10-26 | Advanced Medical Optics, Inc. | Ophthalmic lens combinations |
US8062361B2 (en) * | 2001-01-25 | 2011-11-22 | Visiogen, Inc. | Accommodating intraocular lens system with aberration-enhanced performance |
US20120016349A1 (en) | 2001-01-29 | 2012-01-19 | Amo Development, Llc. | Hybrid ophthalmic interface apparatus and method of interfacing a surgical laser with an eye |
IL141529A0 (en) * | 2001-02-20 | 2002-03-10 | Ben Nun Yehoshua | Intraocular lens with scleral fixation capability |
IL145015A0 (en) * | 2001-08-21 | 2002-06-30 | Nun Yehoshua Ben | Accommodating lens |
US20030060878A1 (en) | 2001-08-31 | 2003-03-27 | Shadduck John H. | Intraocular lens system and method for power adjustment |
US7763069B2 (en) | 2002-01-14 | 2010-07-27 | Abbott Medical Optics Inc. | Accommodating intraocular lens with outer support structure |
US7150759B2 (en) * | 2002-01-14 | 2006-12-19 | Advanced Medical Optics, Inc. | Multi-mechanistic accommodating intraocular lenses |
US7261737B2 (en) * | 2002-12-12 | 2007-08-28 | Powervision, Inc. | Accommodating intraocular lens system and method |
US8048155B2 (en) | 2002-02-02 | 2011-11-01 | Powervision, Inc. | Intraocular implant devices |
US6966649B2 (en) * | 2002-08-12 | 2005-11-22 | John H Shadduck | Adaptive optic lens system and method of use |
US7125422B2 (en) * | 2002-10-25 | 2006-10-24 | Quest Vision Technology, Inc. | Accommodating intraocular lens implant |
US20040082993A1 (en) | 2002-10-25 | 2004-04-29 | Randall Woods | Capsular intraocular lens implant having a refractive liquid therein |
US20040082995A1 (en) * | 2002-10-25 | 2004-04-29 | Randall Woods | Telescopic intraocular lens implant for treating age-related macular degeneration |
US7662180B2 (en) | 2002-12-05 | 2010-02-16 | Abbott Medical Optics Inc. | Accommodating intraocular lens and method of manufacture thereof |
US7217288B2 (en) | 2002-12-12 | 2007-05-15 | Powervision, Inc. | Accommodating intraocular lens having peripherally actuated deflectable surface and method |
US8361145B2 (en) | 2002-12-12 | 2013-01-29 | Powervision, Inc. | Accommodating intraocular lens system having circumferential haptic support and method |
JP4480585B2 (en) * | 2002-12-12 | 2010-06-16 | パワービジョン, インコーポレイテッド | Intraocular lens adjustment and method |
US7247168B2 (en) * | 2002-12-12 | 2007-07-24 | Powervision, Inc. | Accommodating intraocular lens system and method |
US8328869B2 (en) | 2002-12-12 | 2012-12-11 | Powervision, Inc. | Accommodating intraocular lenses and methods of use |
US10835373B2 (en) | 2002-12-12 | 2020-11-17 | Alcon Inc. | Accommodating intraocular lenses and methods of use |
US7001427B2 (en) * | 2002-12-17 | 2006-02-21 | Visioncare Ophthalmic Technologies, Inc. | Intraocular implants |
EP1599748A4 (en) | 2003-03-06 | 2007-10-24 | John H Shadduck | Adaptive optic lens and method of making |
GB0319408D0 (en) * | 2003-08-19 | 2003-09-17 | Chawdhary Satish | Intraocular device |
WO2005048882A1 (en) * | 2003-11-18 | 2005-06-02 | Medennium, Inc. | Accommodative intraocular lens and method of implantation |
US20050131535A1 (en) * | 2003-12-15 | 2005-06-16 | Randall Woods | Intraocular lens implant having posterior bendable optic |
IL161706A0 (en) * | 2004-04-29 | 2004-09-27 | Nulens Ltd | Intraocular lens fixation device |
WO2006040759A1 (en) * | 2004-10-13 | 2006-04-20 | Nulens Ltd | Accommodating intraocular lens (aiol), and aiol assemblies including same |
US9872763B2 (en) | 2004-10-22 | 2018-01-23 | Powervision, Inc. | Accommodating intraocular lenses |
US7842086B2 (en) * | 2005-01-07 | 2010-11-30 | Visioncare Ophthalmic Technologies, Inc. | Mirror implant |
US8529560B2 (en) * | 2005-03-04 | 2013-09-10 | The Invention Science Fund I, Llc | Hair treatment system |
CA2601351A1 (en) * | 2005-03-30 | 2006-10-05 | Nulens Ltd | Accommodating intraocular lens (aiol) assemblies, and discrete components therfor |
US8038711B2 (en) * | 2005-07-19 | 2011-10-18 | Clarke Gerald P | Accommodating intraocular lens and methods of use |
US20070027541A1 (en) * | 2005-07-26 | 2007-02-01 | Visioncare Ophthalmic Technologies Inc. | Intraocular devices and methods for implantation thereof |
US8088161B2 (en) * | 2005-07-28 | 2012-01-03 | Visioncare Ophthalmic Technologies Inc. | Compressed haptics |
EP1924222A1 (en) * | 2005-08-05 | 2008-05-28 | Visiogen, Inc. | Accommodating diffractive intraocular lens |
US20070032868A1 (en) * | 2005-08-08 | 2007-02-08 | Randall Woods | Capsular shape-restoring device |
DE102005038542A1 (en) | 2005-08-16 | 2007-02-22 | Forschungszentrum Karlsruhe Gmbh | Artificial accommodation system |
US9636213B2 (en) * | 2005-09-30 | 2017-05-02 | Abbott Medical Optics Inc. | Deformable intraocular lenses and lens systems |
US8241355B2 (en) | 2005-10-28 | 2012-08-14 | Abbott Medical Optics Inc. | Haptic for accommodating intraocular lens |
US20070168027A1 (en) * | 2006-01-13 | 2007-07-19 | Brady Daniel G | Accommodating diffractive intraocular lens |
US8377125B2 (en) * | 2006-04-05 | 2013-02-19 | Anew Optics, Inc. | Intraocular lens with accommodation |
JP2009534129A (en) * | 2006-04-18 | 2009-09-24 | カスケード オフタルミクス | Intraocular pressure attenuator |
US7918886B2 (en) * | 2006-05-25 | 2011-04-05 | Visioncare Ophthalmic Technologies Inc. | Double insertion intraocular implant |
US20090198247A1 (en) * | 2006-08-25 | 2009-08-06 | Nulens Ltd. | Intraocular lens implantation kit |
AU2007338100B2 (en) | 2006-12-22 | 2014-01-30 | Amo Groningen Bv | Accommodating intraocular lens, lens system and frame therefor |
SG177222A1 (en) * | 2006-12-28 | 2012-01-30 | Int Inst Cancer Immunology Inc | Hla-a*1101-restricted wt1 peptide and pharmaceutical composition comprising the same |
CA2674018C (en) | 2006-12-29 | 2015-05-26 | Advanced Medical Optics, Inc. | Multifocal accommodating intraocular lens |
US20080161914A1 (en) | 2006-12-29 | 2008-07-03 | Advanced Medical Optics, Inc. | Pre-stressed haptic for accommodating intraocular lens |
US7713299B2 (en) | 2006-12-29 | 2010-05-11 | Abbott Medical Optics Inc. | Haptic for accommodating intraocular lens |
US8034106B2 (en) * | 2007-02-02 | 2011-10-11 | Adoptics Ag | Interfacial refraction accommodating lens (IRAL) |
US7857850B2 (en) * | 2007-02-02 | 2010-12-28 | Adoptics Ag | Interfacial refraction accommodating lens (IRAL) |
DE102007008374B4 (en) * | 2007-02-21 | 2008-11-20 | Forschungszentrum Karlsruhe Gmbh | Implantable system for determining the accommodation requirement by measuring the eyeball orientation using an external magnetic field |
CN101678149B (en) | 2007-02-21 | 2013-07-17 | 力景公司 | Polymeric materials suitable for ophthalmic devices and methods of manufacture |
US7986465B1 (en) | 2007-03-01 | 2011-07-26 | Rhevision Technology, Inc. | Systems and methods for effecting zoom and focus using fluidic adaptive lenses |
US8273123B2 (en) * | 2007-03-05 | 2012-09-25 | Nulens Ltd. | Unitary accommodating intraocular lenses (AIOLs) and discrete base members for use therewith |
USD702346S1 (en) | 2007-03-05 | 2014-04-08 | Nulens Ltd. | Haptic end plate for use in an intraocular assembly |
JP5752415B2 (en) | 2007-07-23 | 2015-07-22 | パワーヴィジョン・インコーポレーテッド | Correction of the refractive power of the lens after implantation |
CA2696450C (en) | 2007-07-23 | 2016-02-16 | Terah Whiting Smiley | Lens delivery system |
US9610155B2 (en) | 2008-07-23 | 2017-04-04 | Powervision, Inc. | Intraocular lens loading systems and methods of use |
US8314927B2 (en) | 2007-07-23 | 2012-11-20 | Powervision, Inc. | Systems and methods for testing intraocular lenses |
US8968396B2 (en) | 2007-07-23 | 2015-03-03 | Powervision, Inc. | Intraocular lens delivery systems and methods of use |
US8668734B2 (en) | 2010-07-09 | 2014-03-11 | Powervision, Inc. | Intraocular lens delivery devices and methods of use |
EP2671541B1 (en) | 2007-07-23 | 2019-04-17 | PowerVision, Inc. | Accommodating intraocular lenses |
US8480734B2 (en) * | 2007-12-27 | 2013-07-09 | Anew Optics, Inc. | Intraocular lens with accommodation |
US8034108B2 (en) | 2008-03-28 | 2011-10-11 | Abbott Medical Optics Inc. | Intraocular lens having a haptic that includes a cap |
US8254034B1 (en) | 2008-03-31 | 2012-08-28 | Rhevision Technology, Inc. | Fluidic adaptive lens with a lens membrane having suppressed fluid permeability |
DE102008023726B4 (en) | 2008-05-15 | 2011-01-27 | Karlsruher Institut für Technologie | Implantable device for providing the ability to accommodate using internal energy |
ES2377456T3 (en) | 2008-07-24 | 2012-03-27 | Nulens Ltd | Accommodative intraocular lens capsules (IOLs) |
US8043372B2 (en) | 2008-10-14 | 2011-10-25 | Abbott Medical Optics Inc. | Intraocular lens and capsular ring |
EP2358305A4 (en) * | 2008-11-26 | 2014-02-26 | Anew Optics Inc | Intraocular lens optic |
US10010405B2 (en) | 2008-11-26 | 2018-07-03 | Anew Aol Technologies, Inc. | Haptic devices for intraocular lens |
CN102292051A (en) * | 2008-11-26 | 2011-12-21 | 安纽光学公司 | Haptic devices for intraocular lens |
US10299913B2 (en) | 2009-01-09 | 2019-05-28 | Powervision, Inc. | Accommodating intraocular lenses and methods of use |
WO2010081093A2 (en) | 2009-01-09 | 2010-07-15 | Powervision, Inc. | Intraocular lenses and methods of accounting for capsule size variability and post-implant changes in the eye |
US20100228260A1 (en) * | 2009-03-04 | 2010-09-09 | Anew Optics, Inc. | Injector for intraocular lens |
AU2010266022B2 (en) | 2009-06-26 | 2015-04-23 | Johnson & Johnson Surgical Vision, Inc. | Accommodating intraocular lenses |
WO2011017322A1 (en) | 2009-08-03 | 2011-02-10 | Abbott Medical Optics Inc. | Intraocular lens for providing accomodative vision |
WO2011031557A1 (en) * | 2009-08-27 | 2011-03-17 | Abbott Medical Optics Inc. | Fixation of opthalmic implants |
WO2011026068A2 (en) | 2009-08-31 | 2011-03-03 | Powervision, Inc. | Lens capsule size estimation |
DE102009059229A1 (en) | 2009-12-18 | 2011-06-22 | Karlsruher Institut für Technologie, 76131 | Implantable system for determining accommodation needs |
US8900298B2 (en) | 2010-02-23 | 2014-12-02 | Powervision, Inc. | Fluid for accommodating intraocular lenses |
JP2013525028A (en) | 2010-04-27 | 2013-06-20 | レンスゲン、インコーポレイテッド | Adjustable intraocular lens / device |
WO2011138790A1 (en) | 2010-05-06 | 2011-11-10 | Nulens Ltd | Injector apparatus for injecting intraocular lens |
US9220590B2 (en) | 2010-06-10 | 2015-12-29 | Z Lens, Llc | Accommodative intraocular lens and method of improving accommodation |
WO2012006186A2 (en) * | 2010-06-29 | 2012-01-12 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Accommodating intraocular lens with deformable material |
JP2013537457A (en) | 2010-08-15 | 2013-10-03 | ニューレンズ・リミテッド | Individually assembled monolithic AIOL assemblies and AIOL assemblies containing them |
WO2012106673A1 (en) | 2011-02-04 | 2012-08-09 | Forsight Labs, Llc | Intraocular accommodating lens |
NL2009597C2 (en) * | 2011-10-11 | 2014-09-04 | Akkolens Int Bv | Accommodating intraocular lenses with artificial pupil. |
US10433949B2 (en) | 2011-11-08 | 2019-10-08 | Powervision, Inc. | Accommodating intraocular lenses |
US8500806B1 (en) | 2012-01-31 | 2013-08-06 | Andrew F. Phillips | Accommodating intraocular lens |
US9381081B2 (en) | 2012-03-12 | 2016-07-05 | Doci Innovations GmbH (Claus Simandi) | Intraocular lens having helical haptics of shape memory |
US9084674B2 (en) | 2012-05-02 | 2015-07-21 | Abbott Medical Optics Inc. | Intraocular lens with shape changing capability to provide enhanced accomodation and visual acuity |
US8945215B2 (en) | 2012-05-10 | 2015-02-03 | Abbott Medical Optics Inc. | Accommodating intraocular lens with a compressible inner structure |
US9364318B2 (en) | 2012-05-10 | 2016-06-14 | Z Lens, Llc | Accommodative-disaccommodative intraocular lens |
ES2457840B1 (en) | 2012-09-28 | 2015-02-16 | Universidad De Murcia | Variable power accommodative intraocular lens and variable power accommodative intraocular lens set and capsular ring |
EP2934382B1 (en) | 2012-12-21 | 2021-08-11 | Johnson & Johnson Surgical Vision, Inc. | Accommodating intraocular lens providing progressive power change |
US9186244B2 (en) | 2012-12-21 | 2015-11-17 | Lensgen, Inc. | Accommodating intraocular lens |
BR112015016867A2 (en) | 2013-01-15 | 2017-10-03 | Medicem Ophthalmic Cy Ltd [Cy/Cy] | BIOANALOGICAL INTRAOCULAR LENS AND ITS IMPLANT |
EP2967842B1 (en) | 2013-03-15 | 2020-11-04 | Alcon Inc. | Method of reconfiguring an intraocular lens for delivery to a delivery device |
GB2518378A (en) * | 2013-09-18 | 2015-03-25 | Timothy Paine | Intraocular Lenses |
WO2015066502A1 (en) | 2013-11-01 | 2015-05-07 | Thomas Silvestrini | Accomodating intraocular lens device |
WO2015066532A1 (en) | 2013-11-01 | 2015-05-07 | Daniel Brady | Two-part accommodating intraocular lens device |
US9662199B2 (en) | 2013-11-26 | 2017-05-30 | Strathspey Crown Holdings, LLC | Intraocular lens having input and output electronics |
JP6591525B2 (en) | 2014-03-28 | 2019-10-16 | フォーサイト・ラブス・リミテッド・ライアビリティ・カンパニーForSight Labs, LLC | Perspective accommodation type intraocular lens |
US10004596B2 (en) | 2014-07-31 | 2018-06-26 | Lensgen, Inc. | Accommodating intraocular lens device |
US10647831B2 (en) | 2014-09-23 | 2020-05-12 | LensGens, Inc. | Polymeric material for accommodating intraocular lenses |
GB2532073A (en) | 2014-11-07 | 2016-05-11 | Paine Timothy | Accommodating intraocular lens systems and intraocuolar lens focuser |
US10265163B2 (en) | 2014-12-27 | 2019-04-23 | Jitander Dudee | Accommodating intraocular lens assembly |
EP3370647B8 (en) | 2015-11-06 | 2021-06-30 | Alcon Inc. | Accommodating intraocular lenses and methods of manufacturing |
CN113180886A (en) | 2015-12-01 | 2021-07-30 | 雷恩斯根公司 | Accommodating intraocular lens device |
ES2631354B1 (en) | 2016-02-29 | 2019-10-09 | Univ Murcia | INTRAOCULAR OPENING CORRECTING LENS |
IL245775A0 (en) * | 2016-05-22 | 2016-08-31 | Joshua Ben Nun | Hybrid accommodating intraocular lens |
EP3463188B1 (en) | 2016-05-27 | 2023-04-26 | LensGen, Inc. | Lens oil having a narrow molecular weight distribution for intraocular lens devices |
JP2019520966A (en) | 2016-06-23 | 2019-07-25 | メディセム インスティテュート エス.アール.オー. | Photo-adjustable hydrogel and bioanalogous intraocular lens |
JP7074960B2 (en) | 2016-08-24 | 2022-05-25 | カール ツァイス メディテック アーゲー | Dual Mode Adjustable-Non-Adjustable Intraocular Lens |
WO2018081595A1 (en) | 2016-10-28 | 2018-05-03 | Forsight Vision6, Inc. | Accommodating intraocular lens and methods of implantation |
WO2019022608A1 (en) | 2017-07-27 | 2019-01-31 | Akkolens International B.V. | Accommodating intraocular lens with free form optical surfaces |
EP3681438A1 (en) | 2017-09-11 | 2020-07-22 | AMO Groningen B.V. | Methods and apparatuses to increase intraocular lenses positional stability |
GB2578639A (en) | 2018-11-02 | 2020-05-20 | Rayner Intraocular Lenses Ltd | Hybrid accommodating intraocular lens assemblages including discrete lens unit with segmented lens haptics |
NL2025405B1 (en) | 2019-04-23 | 2021-05-31 | Akkolens Int B V | Accommodating intraocular lens with elastically contracting haptics |
DE112020003939T5 (en) | 2019-08-19 | 2022-05-19 | Akkolens International B.V. | Accommodative intraocular lens combination with independent fixed and variable power lens parts |
EP4041131A4 (en) | 2019-10-04 | 2023-11-15 | Alcon Inc. | Adjustable intraocular lenses and methods of post-operatively adjusting intraocular lenses |
Family Cites Families (150)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3950082A (en) * | 1973-01-10 | 1976-04-13 | David Volk | Ophthalmic lens for presbyopia and aphakia |
US3950080A (en) * | 1974-11-25 | 1976-04-13 | Mckee Clyde M | Rear view mirror actuating device |
US4122556A (en) * | 1977-03-23 | 1978-10-31 | Stanley Poler | Intra-ocular lens |
US4254509A (en) * | 1979-04-09 | 1981-03-10 | Tennant Jerald L | Accommodating intraocular implant |
US4298994A (en) | 1979-10-26 | 1981-11-10 | Clayman Henry M | Posterior chamber intra-ocular transplant device |
USRE31963E (en) * | 1980-07-14 | 1985-08-06 | Intraocular lenses | |
US4340979A (en) * | 1981-03-18 | 1982-07-27 | Kelman Charles D | Intraocular lens |
JPS589992A (en) * | 1981-07-09 | 1983-01-20 | Mitsubishi Keikinzoku Kogyo Kk | Anode paste for electrolytic furnace for aluminum |
US4446581A (en) * | 1981-09-02 | 1984-05-08 | Blake L W | Intraocular lens with free-ended sizing prong |
US4409690A (en) * | 1981-09-24 | 1983-10-18 | Gess Lowell A | Intraocular lenses |
US4409691A (en) * | 1981-11-02 | 1983-10-18 | Levy Chauncey F | Focussable intraocular lens |
US4445998A (en) | 1981-12-02 | 1984-05-01 | Toyo Kohan Co., Ltd. | Method for producing a steel lithographic plate |
US4589147A (en) * | 1982-03-04 | 1986-05-20 | Nevyas Herbert J | Intraocular lens |
US4494254A (en) * | 1982-05-03 | 1985-01-22 | Osvaldo Lopez | Intraocular lens |
US4476591A (en) * | 1982-10-07 | 1984-10-16 | Arnott Eric J | Lens implants for insertion in the human eye |
US4676794A (en) * | 1983-02-10 | 1987-06-30 | Kelman Charles D | Intraocular lens |
US4575374A (en) | 1983-02-16 | 1986-03-11 | Anis Aziz Y | Flexible anterior chamber lens |
US4591358A (en) * | 1983-03-31 | 1986-05-27 | Kelman Charles D | Intraocular lens |
US4556998A (en) | 1983-08-04 | 1985-12-10 | Siepser Steven B | Artificial intraocular lenses and method for their surgical implantation |
US4615701A (en) * | 1984-01-03 | 1986-10-07 | Woods Randall L | Intraocular lens and method of implantation thereof |
US4530117A (en) * | 1984-01-30 | 1985-07-23 | Kelman Charles D | Surgical instrument for and method of inserting a posterior chamber lens in an eye |
GB2154930B (en) * | 1984-02-28 | 1988-11-09 | Microsurgical Administrative S | Forceps |
US4969897A (en) * | 1984-09-12 | 1990-11-13 | Kalb Irvin M | Intraocular lens with retractable leg |
US4976732A (en) | 1984-09-12 | 1990-12-11 | International Financial Associates Holdings, Inc. | Optical lens for the human eye |
US4581033A (en) * | 1985-01-08 | 1986-04-08 | Callahan Wayne B | Unitary intraocular lens providing four-point support |
US5171268A (en) | 1985-12-09 | 1992-12-15 | Allergan, Inc. | Haptic to optic attachment for a soft iol |
US4750904A (en) * | 1986-03-31 | 1988-06-14 | Price Jr Francis W | Posterior chamber intraocular lens with improved fixation where the posterior capsule is not present to serve as a fixation platform |
US4842601A (en) * | 1987-05-18 | 1989-06-27 | Smith S Gregory | Accommodating intraocular lens and method of implanting and using same |
US5282851A (en) | 1987-07-07 | 1994-02-01 | Jacob Labarre Jean | Intraocular prostheses |
US4932968A (en) * | 1987-07-07 | 1990-06-12 | Caldwell Delmar R | Intraocular prostheses |
US4865601A (en) * | 1987-07-07 | 1989-09-12 | Caldwell Delmar R | Intraocular prostheses |
US4808181A (en) * | 1987-08-07 | 1989-02-28 | Kelman Charles D | Intraocular lens having roughened surface area |
US4888012A (en) * | 1988-01-14 | 1989-12-19 | Gerald Horn | Intraocular lens assemblies |
US5176701A (en) * | 1988-05-27 | 1993-01-05 | Jarmila Dusek | Medical forceps instrument for implanting intraocular lenses |
US4932966A (en) | 1988-08-15 | 1990-06-12 | Storz Instrument Company | Accommodating intraocular lens |
US4990159A (en) * | 1988-12-02 | 1991-02-05 | Kraff Manus C | Intraocular lens apparatus with haptics of varying cross-sectional areas |
US4892543A (en) * | 1989-02-02 | 1990-01-09 | Turley Dana F | Intraocular lens providing accomodation |
US5078742A (en) * | 1989-08-28 | 1992-01-07 | Elie Dahan | Posterior chamber lens implant |
US4957505A (en) * | 1989-11-03 | 1990-09-18 | Mcdonald Henry H | Cannulated spring forceps for intra-ocular lens implantation method |
US5480426A (en) * | 1989-12-26 | 1996-01-02 | Chu; Milton W. | Method of implanting an intraocular lens having haptics for scleral fixation |
US5336262A (en) * | 1989-12-26 | 1994-08-09 | Chu Milton W | Intraocular lens with haptics for scleral fixation and method for using it |
US5476514A (en) * | 1990-04-27 | 1995-12-19 | Cumming; J. Stuart | Accommodating intraocular lens |
US6197059B1 (en) * | 1990-04-27 | 2001-03-06 | Medevec Licensing, B.V. | Accomodating intraocular lens |
US5766244A (en) * | 1991-05-23 | 1998-06-16 | Binder; Helmut | Intraocular artificial lens and method for fabricating same |
WO1993002639A1 (en) | 1991-08-06 | 1993-02-18 | Autogenesis Technologies, Inc. | Injectable collagen-based compositions for making intraocular lens |
US5275623A (en) * | 1991-11-18 | 1994-01-04 | Faezeh Sarfarazi | Elliptical accommodative intraocular lens for small incision surgery |
US6423094B1 (en) * | 1991-11-18 | 2002-07-23 | Faezeh M. Sarfarazi | Accommodative lens formed from sheet material |
US5476512A (en) | 1991-11-18 | 1995-12-19 | Sarfarazi; Faezeh | Anterior capsular fixating lens for posterior capsular ruptures |
US5354331A (en) * | 1992-07-15 | 1994-10-11 | Schachar Ronald A | Treatment of presbyopia and other eye disorders |
US5288293A (en) * | 1992-09-24 | 1994-02-22 | Donnell Jr Francis E O | In vivo modification of refractive power of an intraocular lens implant |
US5346502A (en) * | 1993-04-15 | 1994-09-13 | Ultracision, Inc. | Laparoscopic ultrasonic surgical instrument and methods for manufacturing the instruments |
US5571177A (en) | 1993-06-14 | 1996-11-05 | Allergan | IOL structured for post-operative re-positioning and method for post-operative IOL re-positioning |
DE69414201T2 (en) | 1993-07-28 | 1999-05-06 | Iolab Corp | Intraocular lens with unbreakable brackets |
US5584304A (en) | 1993-11-18 | 1996-12-17 | Allergan, Inc. | Method of inserting an IOL using a forceps inside a folding tube |
DE4340205C1 (en) * | 1993-11-25 | 1995-04-20 | Dieter W Klaas | Intraocular lens with accommodation device |
US5489302A (en) | 1994-05-24 | 1996-02-06 | Skottun; Bernt C. | Accommodating intraocular lens |
US5484447A (en) * | 1994-07-26 | 1996-01-16 | Duckworth & Kent Limited | Calipers for use in ophthalmic surgery |
DE69633110T2 (en) * | 1995-02-15 | 2005-01-05 | Medevec Licensing B.V. | CUSTOMIZABLE INTRAOCULAR LENS WITH T-SHAPED HOLDERS |
US5628795A (en) * | 1995-03-15 | 1997-05-13 | Langerman David W | Spare parts for use in ophthalmic surgical procedures |
US5607472A (en) * | 1995-05-09 | 1997-03-04 | Emory University | Intraocular lens for restoring accommodation and allows adjustment of optical power |
US5684637A (en) | 1995-07-19 | 1997-11-04 | Floyd; Johnnie E. | Fluid filled and pressurized lens with flexible optical boundary having variable focal length |
US5968094A (en) * | 1995-09-18 | 1999-10-19 | Emmetropia, Inc. | Compound intraocular lens |
WO1997012564A1 (en) * | 1995-10-06 | 1997-04-10 | Cumming J Stuart | Intraocular lenses with fixated haptics |
US5984962A (en) | 1996-01-22 | 1999-11-16 | Quantum Vision, Inc. | Adjustable intraocular lens |
FR2744908B1 (en) * | 1996-02-20 | 1998-06-12 | W K Et Associes | MYOPIC INTRAOCULAR IMPLANT |
US20040148022A1 (en) * | 1996-03-18 | 2004-07-29 | Eggleston Harry C. | Modular intraocular implant |
JPH09294720A (en) * | 1996-04-30 | 1997-11-18 | Nikon Corp | Ophthalmologic instrument |
US5752960A (en) * | 1996-05-31 | 1998-05-19 | Nallakrishnan; Ravi | Intraocular lens insertion forceps |
US5919230A (en) * | 1997-03-18 | 1999-07-06 | Sambursky; Daniel Louis. | Intraocular lens implant and method of making same |
US6027531A (en) | 1997-10-14 | 2000-02-22 | Tassignon; Marie-Joseb. R. | Intraocular lens and method for preventing secondary opacification |
US8663235B2 (en) | 1997-10-14 | 2014-03-04 | Marie-José B. Tassignon | Bag-in-the-lens intraocular lens with removable optic |
US5843188A (en) * | 1997-10-20 | 1998-12-01 | Henry H. McDonald | Accommodative lens implantation |
US6605093B1 (en) * | 1997-10-24 | 2003-08-12 | Tekia, Inc. | Device and method for use with an ophthalmologic insertor apparatus |
US6129759A (en) * | 1997-12-10 | 2000-10-10 | Staar Surgical Company, Inc. | Frosted haptic intraocular lens |
US6007579A (en) | 1998-01-15 | 1999-12-28 | Visioncare Ltd. | Intraocular carrying member with attachment for telescope |
AU4673599A (en) * | 1998-06-02 | 1999-12-20 | Microoptix, Llc | Anterior chamber intraocular lens apparatus and method |
US6197057B1 (en) * | 1998-10-27 | 2001-03-06 | Gholam A. Peyman | Lens conversion system for teledioptic or difractive configurations |
US6231603B1 (en) * | 1998-11-10 | 2001-05-15 | Allergan Sales, Inc. | Accommodating multifocal intraocular lens |
US6117171A (en) | 1998-12-23 | 2000-09-12 | Skottun; Bernt Christian | Encapsulated accommodating intraocular lens |
FR2787991B1 (en) | 1998-12-31 | 2001-05-25 | Medicale De Prec S M P Sa Soc | DEVICE FOR TREATING PRESBYGIA OR OTHER EYE CONDITION |
US6164282A (en) | 1999-01-27 | 2000-12-26 | Allergan Sales, Inc. | Methods for restoring and/or enhancing accommodation in pseudo phakia |
DE19904441C1 (en) * | 1999-02-01 | 2000-09-07 | Preusner Paul Rolf | Accomodative intraocular lens system |
JP3040101B1 (en) * | 1999-02-12 | 2000-05-08 | 毅 杉浦 | Ciliary sulcus pad in posterior chamber lens transciliary scleral stitch of the eyeball |
US6488708B2 (en) | 1999-04-09 | 2002-12-03 | Faezeh Sarfarazi | Open chamber, elliptical, accommodative intraocular lens system |
US6790232B1 (en) | 1999-04-30 | 2004-09-14 | Advanced Medical Optics, Inc. | Multifocal phakic intraocular lens |
US20030060881A1 (en) | 1999-04-30 | 2003-03-27 | Advanced Medical Optics, Inc. | Intraocular lens combinations |
US6616692B1 (en) | 1999-04-30 | 2003-09-09 | Advanced Medical Optics, Inc. | Intraocular lens combinations |
US6406494B1 (en) * | 1999-04-30 | 2002-06-18 | Allergan Sales, Inc. | Moveable intraocular lens |
US6200342B1 (en) * | 1999-05-11 | 2001-03-13 | Marie-Jose B. Tassignon | Intraocular lens with accommodative properties |
US6280469B1 (en) * | 1999-05-11 | 2001-08-28 | Mark A. Terry | Implantable iris device for the eye, and method of installing same |
FR2794965B1 (en) | 1999-06-21 | 2001-07-20 | Ioltechnologie Production | INTRAOCULAR TENSION RING FOR PRESBYTIA CORRECTION |
DE19936666C2 (en) * | 1999-08-04 | 2002-05-23 | Marianne Jahn | Adjustable intraocular lens and method of making it |
US6299641B1 (en) * | 1999-09-10 | 2001-10-09 | Randall Woods | Intraocular lens implant having eye accommodating capabilities |
US6280471B1 (en) * | 1999-09-16 | 2001-08-28 | Gholam A. Peyman | Glare-free intraocular lens and method for using the same |
US6599317B1 (en) * | 1999-09-17 | 2003-07-29 | Advanced Medical Optics, Inc. | Intraocular lens with a translational zone |
US6193750B1 (en) * | 1999-10-15 | 2001-02-27 | Medevec Licensing, B.V. | Collars for lens loops |
US6342073B1 (en) * | 1999-12-30 | 2002-01-29 | J. Stuart Cumming | Intraocular lens for posterior vaulting |
US6520691B2 (en) * | 2000-01-31 | 2003-02-18 | Pentax Corporation | Lens barrier opening/closing device of a movable lens barrel |
US6570718B2 (en) * | 2000-02-01 | 2003-05-27 | Pentax Corporation | Zoom lens having a cam mechanism |
FR2804860B1 (en) * | 2000-02-16 | 2002-04-12 | Humanoptics Ag | ACCOMODATIVE CRYSTALLINE IMPLANT |
US6554860B2 (en) * | 2000-05-15 | 2003-04-29 | Bausch & Lomb Incorporated | Foldable iris fixated intraocular lenses |
US6849091B1 (en) | 2000-05-19 | 2005-02-01 | Eyeonics, Inc. | Lens assembly for depth of focus |
US6506212B2 (en) * | 2000-07-07 | 2003-01-14 | Medennium, Inc. | Anatomically compatible posterior chamber phakic refractive lenses |
US7137994B2 (en) | 2000-07-11 | 2006-11-21 | John Hopkins University | Injectable bag intraocular lens system, inserting device for use therewith, method for inserting an injectable bag intraocular lens within a human eye, methods for treating aphakia and system kits |
US6596026B1 (en) * | 2000-11-27 | 2003-07-22 | Visioncare Ophthalmic Technologies, Inc. | Telescopic intraocular lens |
US6464725B2 (en) * | 2001-01-23 | 2002-10-15 | Bernt Christian Skotton | Two-lens adjustable intraocular lens system |
US6827738B2 (en) | 2001-01-30 | 2004-12-07 | Timothy R. Willis | Refractive intraocular implant lens and method |
US20020103535A1 (en) * | 2001-01-31 | 2002-08-01 | Valdemar Portney | Intraocular lens for double-fold implantation |
IL141529A0 (en) | 2001-02-20 | 2002-03-10 | Ben Nun Yehoshua | Intraocular lens with scleral fixation capability |
US6443954B1 (en) * | 2001-04-24 | 2002-09-03 | Dale G. Bramlet | Femoral nail intramedullary system |
US6638305B2 (en) * | 2001-05-15 | 2003-10-28 | Advanced Medical Optics, Inc. | Monofocal intraocular lens convertible to multifocal intraocular lens |
US6524340B2 (en) | 2001-05-23 | 2003-02-25 | Henry M. Israel | Accommodating intraocular lens assembly |
US7118597B2 (en) * | 2001-06-22 | 2006-10-10 | David Miller | Accommodating intraocular lens |
TW523408B (en) | 2001-08-14 | 2003-03-11 | Chuen-Yi Lin | Automatically adjustable artificial crystal |
IL145015A0 (en) | 2001-08-21 | 2002-06-30 | Nun Yehoshua Ben | Accommodating lens |
US6443985B1 (en) * | 2001-08-27 | 2002-09-03 | Randall Woods | Intraocular lens implant having eye accommodating capabilities |
US20030097177A1 (en) * | 2001-11-21 | 2003-05-22 | Tran Son Trung | Posterior chamber phakic lens |
US7097660B2 (en) * | 2001-12-10 | 2006-08-29 | Valdemar Portney | Accommodating intraocular lens |
US7037338B2 (en) | 2001-12-14 | 2006-05-02 | Toshiyuki Nagamoto | Intraocular ring assembly and artificial lens kit |
WO2003059208A2 (en) | 2002-01-14 | 2003-07-24 | Advanced Medical Optics, Inc. | Accommodating intraocular lens with integral capsular bag ring |
US8048155B2 (en) | 2002-02-02 | 2011-11-01 | Powervision, Inc. | Intraocular implant devices |
US7261737B2 (en) | 2002-12-12 | 2007-08-28 | Powervision, Inc. | Accommodating intraocular lens system and method |
US20030187504A1 (en) * | 2002-04-01 | 2003-10-02 | Weinschenk Joseph I. | Adjustable intraocular lens |
US6898461B2 (en) * | 2002-04-23 | 2005-05-24 | Medtronic, Inc. | Implantable medical device stream processor |
US6966649B2 (en) * | 2002-08-12 | 2005-11-22 | John H Shadduck | Adaptive optic lens system and method of use |
US6972033B2 (en) | 2002-08-26 | 2005-12-06 | Advanced Medical Optics, Inc. | Accommodating intraocular lens assembly with multi-functional capsular bag ring |
US6739722B2 (en) * | 2002-09-04 | 2004-05-25 | Advanced Medical Optics, Inc. | Apparatus and methods for measuring accommodation of a lens in an eye |
FR2844703B1 (en) * | 2002-09-25 | 2005-07-08 | Alain Nicolas Gilg | INTRAOCULAR DEVICE FOR RESTORING THE ACCOMMODATION OF THE EYE WITH PRESBYOPIA |
JP4480585B2 (en) * | 2002-12-12 | 2010-06-16 | パワービジョン, インコーポレイテッド | Intraocular lens adjustment and method |
US20040260395A1 (en) * | 2003-06-19 | 2004-12-23 | Boxer Wachler Brian S. | Ophthalmological zonular stretch segment for treating presbyopia |
JP2005007029A (en) | 2003-06-20 | 2005-01-13 | Me Technica:Kk | Ciliary sulcus guide |
US6960231B2 (en) | 2003-07-14 | 2005-11-01 | Alcon, Inc. | Intraocular lens system |
DE20316792U1 (en) * | 2003-08-26 | 2005-01-05 | Schedler, Markus | Ciliary muscle-operated, accommodative lens implant |
US7976520B2 (en) | 2004-01-12 | 2011-07-12 | Nulens Ltd. | Eye wall anchored fixtures |
IL161706A0 (en) | 2004-04-29 | 2004-09-27 | Nulens Ltd | Intraocular lens fixation device |
US8057217B2 (en) | 2004-09-30 | 2011-11-15 | Bausch + Lomb Incorporated | Apparatus and method for injection molding an intraocular lens device |
WO2006040759A1 (en) | 2004-10-13 | 2006-04-20 | Nulens Ltd | Accommodating intraocular lens (aiol), and aiol assemblies including same |
CA2601351A1 (en) | 2005-03-30 | 2006-10-05 | Nulens Ltd | Accommodating intraocular lens (aiol) assemblies, and discrete components therfor |
RU2339341C2 (en) * | 2005-04-05 | 2008-11-27 | Алькон, Инк. | Intraocular lens |
US20070027541A1 (en) | 2005-07-26 | 2007-02-01 | Visioncare Ophthalmic Technologies Inc. | Intraocular devices and methods for implantation thereof |
US8088161B2 (en) * | 2005-07-28 | 2012-01-03 | Visioncare Ophthalmic Technologies Inc. | Compressed haptics |
US20070088433A1 (en) | 2005-10-17 | 2007-04-19 | Powervision | Accommodating intraocular lens system utilizing direct force transfer from zonules and method of use |
US8801781B2 (en) | 2005-10-26 | 2014-08-12 | Abbott Medical Optics Inc. | Intraocular lens for correcting corneal coma |
US20070129803A1 (en) | 2005-12-06 | 2007-06-07 | C&C Vision International Limited | Accommodative Intraocular Lens |
US7981155B2 (en) | 2005-12-07 | 2011-07-19 | C&C Vision International Limited | Hydrolic accommodating intraocular lens |
US20090198247A1 (en) | 2006-08-25 | 2009-08-06 | Nulens Ltd. | Intraocular lens implantation kit |
CA2674018C (en) | 2006-12-29 | 2015-05-26 | Advanced Medical Optics, Inc. | Multifocal accommodating intraocular lens |
US8034106B2 (en) | 2007-02-02 | 2011-10-11 | Adoptics Ag | Interfacial refraction accommodating lens (IRAL) |
US7857850B2 (en) * | 2007-02-02 | 2010-12-28 | Adoptics Ag | Interfacial refraction accommodating lens (IRAL) |
US8273123B2 (en) | 2007-03-05 | 2012-09-25 | Nulens Ltd. | Unitary accommodating intraocular lenses (AIOLs) and discrete base members for use therewith |
-
2001
- 2001-08-21 IL IL14501501A patent/IL145015A0/en unknown
-
2002
- 2002-08-21 DE DE60238489T patent/DE60238489D1/en not_active Expired - Lifetime
- 2002-08-21 AT AT02760543T patent/ATE489916T1/en not_active IP Right Cessation
- 2002-08-21 US US10/487,005 patent/US7220279B2/en not_active Expired - Fee Related
- 2002-08-21 ES ES02760543T patent/ES2355066T3/en not_active Expired - Lifetime
- 2002-08-21 WO PCT/IL2002/000693 patent/WO2003015669A1/en active Application Filing
- 2002-08-21 IL IL16048402A patent/IL160484A0/en unknown
- 2002-08-21 AU AU2002326134A patent/AU2002326134B2/en not_active Ceased
- 2002-08-21 EP EP02760543A patent/EP1420722B1/en not_active Expired - Lifetime
- 2002-08-21 CA CA002471186A patent/CA2471186C/en not_active Expired - Fee Related
-
2004
- 2004-02-19 IL IL160484A patent/IL160484A/en not_active IP Right Cessation
- 2004-06-21 ZA ZA200404883A patent/ZA200404883B/en unknown
- 2004-11-23 HK HK04109231.6A patent/HK1066160A1/en not_active IP Right Cessation
-
2007
- 2007-04-11 US US11/734,180 patent/US7854764B2/en not_active Expired - Fee Related
-
2010
- 2010-10-18 US US12/906,774 patent/US7998199B2/en not_active Expired - Fee Related
-
2011
- 2011-06-24 US US13/168,046 patent/US8382831B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
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US20110082544A1 (en) | 2011-04-07 |
EP1420722B1 (en) | 2010-12-01 |
WO2003015669A1 (en) | 2003-02-27 |
HK1066160A1 (en) | 2005-03-18 |
IL160484A (en) | 2010-11-30 |
ZA200404883B (en) | 2005-08-11 |
US8382831B2 (en) | 2013-02-26 |
ES2355066T3 (en) | 2011-03-22 |
IL160484A0 (en) | 2004-07-25 |
US7220279B2 (en) | 2007-05-22 |
US20070185574A1 (en) | 2007-08-09 |
US7854764B2 (en) | 2010-12-21 |
DE60238489D1 (en) | 2011-01-13 |
AU2002326134B2 (en) | 2007-04-26 |
CA2471186A1 (en) | 2003-02-27 |
US20040181279A1 (en) | 2004-09-16 |
IL145015A0 (en) | 2002-06-30 |
EP1420722A1 (en) | 2004-05-26 |
AU2002326134C1 (en) | 2003-03-03 |
US20120029632A1 (en) | 2012-02-02 |
US7998199B2 (en) | 2011-08-16 |
ATE489916T1 (en) | 2010-12-15 |
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