CA2410637A1 - Shape memory polymers seeded with dissociated cells for tissue engineering - Google Patents
Shape memory polymers seeded with dissociated cells for tissue engineering Download PDFInfo
- Publication number
- CA2410637A1 CA2410637A1 CA002410637A CA2410637A CA2410637A1 CA 2410637 A1 CA2410637 A1 CA 2410637A1 CA 002410637 A CA002410637 A CA 002410637A CA 2410637 A CA2410637 A CA 2410637A CA 2410637 A1 CA2410637 A1 CA 2410637A1
- Authority
- CA
- Canada
- Prior art keywords
- cells
- shape memory
- scaffold
- seeded
- tissue engineering
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/58—Materials at least partially resorbable by the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C61/00—Shaping by liberation of internal stresses; Making preforms having internal stresses; Apparatus therefor
- B29C61/06—Making preforms having internal stresses, e.g. plastic memory
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L67/00—Compositions of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Compositions of derivatives of such polymers
- C08L67/04—Polyesters derived from hydroxycarboxylic acids, e.g. lactones
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2995/00—Properties of moulding materials, reinforcements, fillers, preformed parts or moulds
- B29K2995/0037—Other properties
- B29K2995/0059—Degradable
- B29K2995/006—Bio-degradable, e.g. bioabsorbable, bioresorbable or bioerodible
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2201/00—Properties
- C08L2201/12—Shape memory
Abstract
Methods and compositions are described herein for reconstruction of different functional tissues. Dissociated cells, differentiated cells, adult mesenchymal stem cells or embryonic stem cells are seeded on a scaffold. The scaffold will consist of a biocompatible, biodegradable shape memory ("SM") polymers. In addition bioactive substances may be incorporated in the scaffold.
Thermoplastic as well as thermoset materials with SM-effect can be used. The shape memory effect will be applied as an interactive link between the cells and the used polymeric scaffold. The degradation kinetics as well as shape memory transition temperature will be tailored by adjusting to monomer ratios of the co-oligomers. The shape memory effect will be used to create a degradation or release of bioactive substances on demand, induce forces on seeded cells or induce proliferation and differentiation of cells.
Thermoplastic as well as thermoset materials with SM-effect can be used. The shape memory effect will be applied as an interactive link between the cells and the used polymeric scaffold. The degradation kinetics as well as shape memory transition temperature will be tailored by adjusting to monomer ratios of the co-oligomers. The shape memory effect will be used to create a degradation or release of bioactive substances on demand, induce forces on seeded cells or induce proliferation and differentiation of cells.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20828500P | 2000-05-31 | 2000-05-31 | |
US60/208,285 | 2000-05-31 | ||
PCT/EP2001/006210 WO2001091822A1 (en) | 2000-05-31 | 2001-05-31 | Shape memory thermoplastics and polymer networks for tissue engineering |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2410637A1 true CA2410637A1 (en) | 2001-12-06 |
CA2410637C CA2410637C (en) | 2007-04-10 |
Family
ID=22774012
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002410637A Expired - Fee Related CA2410637C (en) | 2000-05-31 | 2001-05-31 | Shape memory polymers seeded with dissociated cells for tissue engineering |
Country Status (8)
Country | Link |
---|---|
US (2) | US20040110285A1 (en) |
EP (1) | EP1284756B1 (en) |
AT (1) | ATE275986T1 (en) |
AU (1) | AU2001263946A1 (en) |
CA (1) | CA2410637C (en) |
DE (1) | DE60105593T2 (en) |
ES (1) | ES2230318T3 (en) |
WO (1) | WO2001091822A1 (en) |
Families Citing this family (147)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1142596A1 (en) | 2000-04-03 | 2001-10-10 | Universiteit Gent | Compositions of crosslinkable prepolymers for use in therapeutically active biodegradable implants |
US8158143B2 (en) | 2000-07-14 | 2012-04-17 | Helmholtz-Zentrum Geesthacht Zentrum Fuer Material- Und Kuestenforschung Gmbh | Systems for releasing active ingredients, based on biodegradable or biocompatible polymers with a shape memory effect |
US20060177416A1 (en) | 2003-10-14 | 2006-08-10 | Medivas, Llc | Polymer particle delivery compositions and methods of use |
DE10208211A1 (en) * | 2002-02-26 | 2003-09-11 | Mnemoscience Gmbh | Polymer networks |
DE10217350C1 (en) | 2002-04-18 | 2003-12-18 | Mnemoscience Gmbh | polyesterurethanes |
DE10217351B3 (en) * | 2002-04-18 | 2004-02-12 | Mnemoscience Gmbh | Interpenetrating networks |
US7332160B2 (en) * | 2002-07-12 | 2008-02-19 | Boston Scientific Scimed, Inc. | Medical device and method for tissue removal and repair |
AU2003245872A1 (en) | 2002-07-24 | 2004-02-09 | M 2 Medical A/S | An infusion pump system, an infusion pump unit and an infusion pump |
AU2003277332B2 (en) | 2002-10-11 | 2009-03-12 | University Of Connecticut | Shape memory polymers based on semicrystalline thermoplastic polyurethanes bearing nanostructured hard segments |
US7794494B2 (en) | 2002-10-11 | 2010-09-14 | Boston Scientific Scimed, Inc. | Implantable medical devices |
US7976936B2 (en) | 2002-10-11 | 2011-07-12 | University Of Connecticut | Endoprostheses |
WO2004033553A1 (en) | 2002-10-11 | 2004-04-22 | University Of Connecticut | Crosslinked polycyclooctene |
US7524914B2 (en) | 2002-10-11 | 2009-04-28 | The University Of Connecticut | Shape memory polymers based on semicrystalline thermoplastic polyurethanes bearing nanostructured hard segments |
JP4530990B2 (en) | 2002-10-11 | 2010-08-25 | ユニバーシティ オブ コネチカット | Blends of amorphous and semi-crystalline polymers with shape memory properties |
AU2003280307A1 (en) | 2002-11-05 | 2004-06-07 | M 2 Medical A/S | A disposable wearable insulin dispensing device, a combination of such a device and a programming controller and a method of controlling the operation of such a device |
ATE385814T1 (en) | 2002-12-23 | 2008-03-15 | M2 Medical As | MEDICAL DEVICE FOR DELIVERING INSULIN |
DE10300271A1 (en) | 2003-01-08 | 2004-07-22 | Mnemoscience Gmbh | Photosensitive polymer networks |
US20040220672A1 (en) * | 2003-05-03 | 2004-11-04 | Shadduck John H. | Orthopedic implants, methods of use and methods of fabrication |
DE10340392A1 (en) * | 2003-09-02 | 2005-04-07 | Mnemoscience Gmbh | Amorphous polyester urethane networks with shape-memory properties |
GB0329654D0 (en) | 2003-12-23 | 2004-01-28 | Smith & Nephew | Tunable segmented polyacetal |
WO2005077013A2 (en) | 2004-02-06 | 2005-08-25 | Georgia Tech Research Corporation | Surface directed cellular attachment |
CA2558661C (en) | 2004-02-06 | 2012-09-04 | Georgia Tech Research Corporation | Load bearing biocompatible device |
US8585771B2 (en) | 2004-02-26 | 2013-11-19 | Endosphere, Inc. | Methods and devices to curb appetite and/or to reduce food intake |
US8147561B2 (en) | 2004-02-26 | 2012-04-03 | Endosphere, Inc. | Methods and devices to curb appetite and/or reduce food intake |
US7931693B2 (en) * | 2004-02-26 | 2011-04-26 | Endosphere, Inc. | Method and apparatus for reducing obesity |
WO2005103201A1 (en) | 2004-03-31 | 2005-11-03 | University Of Connecticut | Shape memory main-chain smectic-c elastomers |
US20080132899A1 (en) * | 2004-05-17 | 2008-06-05 | Shadduck John H | Composite implant and method for treating bone abnormalities |
US20060095138A1 (en) * | 2004-06-09 | 2006-05-04 | Csaba Truckai | Composites and methods for treating bone |
DE102004030347B4 (en) * | 2004-06-18 | 2006-08-03 | Aesculap Ag & Co. Kg | implant |
US20060085009A1 (en) * | 2004-08-09 | 2006-04-20 | Csaba Truckai | Implants and methods for treating bone |
US9051411B2 (en) | 2004-08-16 | 2015-06-09 | Lawrence Livermore National Security, Llc | Shape memory polymers |
US11820852B2 (en) | 2004-08-16 | 2023-11-21 | Lawrence Livermore National Security, Llc | Shape memory polymers |
WO2006086011A2 (en) | 2004-08-27 | 2006-08-17 | University Of Connecticut | Crosslinked liquid crystalline polymer, method for the preparation thereof, and articles derived therefrom |
US20060106459A1 (en) * | 2004-08-30 | 2006-05-18 | Csaba Truckai | Bone treatment systems and methods |
US7678116B2 (en) * | 2004-12-06 | 2010-03-16 | Dfine, Inc. | Bone treatment systems and methods |
US8048083B2 (en) * | 2004-11-05 | 2011-11-01 | Dfine, Inc. | Bone treatment systems and methods |
US7559932B2 (en) * | 2004-12-06 | 2009-07-14 | Dfine, Inc. | Bone treatment systems and methods |
US7682378B2 (en) * | 2004-11-10 | 2010-03-23 | Dfine, Inc. | Bone treatment systems and methods for introducing an abrading structure to abrade bone |
US7722620B2 (en) | 2004-12-06 | 2010-05-25 | Dfine, Inc. | Bone treatment systems and methods |
US20060122614A1 (en) * | 2004-12-06 | 2006-06-08 | Csaba Truckai | Bone treatment systems and methods |
US8070753B2 (en) * | 2004-12-06 | 2011-12-06 | Dfine, Inc. | Bone treatment systems and methods |
US7717918B2 (en) | 2004-12-06 | 2010-05-18 | Dfine, Inc. | Bone treatment systems and methods |
US8043361B2 (en) | 2004-12-10 | 2011-10-25 | Boston Scientific Scimed, Inc. | Implantable medical devices, and methods of delivering the same |
EP1871306A4 (en) * | 2005-04-01 | 2012-03-21 | Univ Colorado | A graft fixation device and method |
WO2006105793A1 (en) | 2005-04-06 | 2006-10-12 | M 2 Medical A/S | Method and device for dispensing liquid medicine by means of a twistable element |
US8870915B2 (en) | 2005-05-04 | 2014-10-28 | DePuy Synthes Products, LLC | Joining element |
US8777479B2 (en) | 2008-10-13 | 2014-07-15 | Dfine, Inc. | System for use in bone cement preparation and delivery |
US9066769B2 (en) | 2005-08-22 | 2015-06-30 | Dfine, Inc. | Bone treatment systems and methods |
US8540723B2 (en) | 2009-04-14 | 2013-09-24 | Dfine, Inc. | Medical system and method of use |
US20090012525A1 (en) | 2005-09-01 | 2009-01-08 | Eric Buehlmann | Devices and systems for delivering bone fill material |
WO2007030469A2 (en) * | 2005-09-06 | 2007-03-15 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Transplantable cell growth niche and related compositions and methods |
JP5192384B2 (en) | 2005-09-22 | 2013-05-08 | メディバス エルエルシー | Bis- (α-amino) -diol-diester-containing poly (ester amide) and poly (ester urethane) compositions and methods of use |
WO2007038246A2 (en) * | 2005-09-22 | 2007-04-05 | Medivas, Llc | Solid polymer delivery compositions and methods for use thereof |
US8105279B2 (en) | 2005-09-26 | 2012-01-31 | M2 Group Holdings, Inc. | Dispensing fluid from an infusion pump system |
US8409142B2 (en) | 2005-09-26 | 2013-04-02 | Asante Solutions, Inc. | Operating an infusion pump system |
US7534226B2 (en) | 2005-09-26 | 2009-05-19 | M2 Group Holdings, Inc. | Dispensing fluid from an infusion pump system |
WO2007038060A2 (en) | 2005-09-26 | 2007-04-05 | M2 Medical A/S | Modular infusion pump having two different energy sources |
WO2007056592A2 (en) | 2005-11-08 | 2007-05-18 | M2 Medical A/S | Method and system for manual and autonomous control of an infusion pump |
EP1962894A4 (en) * | 2005-12-07 | 2012-11-14 | Medivas Llc | Method for assembling a polymer-biologic delivery composition |
DE102006017759A1 (en) * | 2006-04-12 | 2007-10-18 | Gkss-Forschungszentrum Geesthacht Gmbh | Shape memory polymer with polyester and polyacrylic segments and methods for its preparation and programming |
JP5445130B2 (en) * | 2006-05-02 | 2014-03-19 | メディバス エルエルシー | Delivery of ophthalmic drugs to the exterior or interior of the eye |
JP5196498B2 (en) * | 2006-05-09 | 2013-05-15 | メディバス エルエルシー | Biodegradable water-soluble polymer |
US9060835B2 (en) | 2006-05-26 | 2015-06-23 | Endosphere, Inc. | Conformationally-stabilized intraluminal device for medical applications |
US20080027456A1 (en) * | 2006-07-19 | 2008-01-31 | Csaba Truckai | Bone treatment systems and methods |
US20080085946A1 (en) * | 2006-08-14 | 2008-04-10 | Mather Patrick T | Photo-tailored shape memory article, method, and composition |
CA2679365C (en) | 2006-11-30 | 2016-05-03 | Smith & Nephew, Inc. | Fiber reinforced composite material |
US8696679B2 (en) | 2006-12-08 | 2014-04-15 | Dfine, Inc. | Bone treatment systems and methods |
US20080188858A1 (en) * | 2007-02-05 | 2008-08-07 | Robert Luzzi | Bone treatment systems and methods |
DE102007010564A1 (en) | 2007-02-22 | 2008-08-28 | Gkss-Forschungszentrum Geesthacht Gmbh | Method for one-step programming of three-molded plastics |
US20080236601A1 (en) * | 2007-03-28 | 2008-10-02 | Medshape Solutions, Inc. | Manufacturing shape memory polymers based on deformability peak of polymer network |
CA2685965A1 (en) * | 2007-03-30 | 2008-10-09 | Medivas, Llc | Bioabsorbable elastomeric polymer networks, cross-linkers and methods of use |
ES2438999T3 (en) * | 2007-04-03 | 2014-01-21 | Dfine, Inc. | Bone treatment systems |
JP5416090B2 (en) | 2007-04-18 | 2014-02-12 | スミス アンド ネフュー ピーエルシー | Expansion molding of shape memory polymer |
US9000066B2 (en) | 2007-04-19 | 2015-04-07 | Smith & Nephew, Inc. | Multi-modal shape memory polymers |
DE602008006181D1 (en) | 2007-04-19 | 2011-05-26 | Smith & Nephew Inc | GRAFT FIXATION |
WO2008137428A2 (en) | 2007-04-30 | 2008-11-13 | Dfine, Inc. | Bone treatment systems and methods |
US7892199B2 (en) | 2007-05-21 | 2011-02-22 | Asante Solutions, Inc. | Occlusion sensing for an infusion pump |
US7981102B2 (en) | 2007-05-21 | 2011-07-19 | Asante Solutions, Inc. | Removable controller for an infusion pump |
US7833196B2 (en) | 2007-05-21 | 2010-11-16 | Asante Solutions, Inc. | Illumination instrument for an infusion pump |
US20110137227A1 (en) * | 2007-07-16 | 2011-06-09 | Mckinley James T | Methods and devices for delivering or delaying lipids within a duodenum |
US20090022772A1 (en) * | 2007-07-17 | 2009-01-22 | Medivas, Llc | Bioabsorbable elastomeric arterial support device and methods of use |
US9597118B2 (en) | 2007-07-20 | 2017-03-21 | Dfine, Inc. | Bone anchor apparatus and method |
US20090029937A1 (en) * | 2007-07-24 | 2009-01-29 | Cornell University | Biodegradable cationic polymer gene transfer compositions and methods of use |
US20090035350A1 (en) | 2007-08-03 | 2009-02-05 | John Stankus | Polymers for implantable devices exhibiting shape-memory effects |
US7717903B2 (en) | 2007-09-06 | 2010-05-18 | M2 Group Holdings, Inc. | Operating an infusion pump system |
US7935076B2 (en) | 2007-09-07 | 2011-05-03 | Asante Solutions, Inc. | Activity sensing techniques for an infusion pump system |
US8287514B2 (en) | 2007-09-07 | 2012-10-16 | Asante Solutions, Inc. | Power management techniques for an infusion pump system |
US8032226B2 (en) | 2007-09-07 | 2011-10-04 | Asante Solutions, Inc. | User profile backup system for an infusion pump device |
DE102008004574A1 (en) * | 2008-01-09 | 2009-07-16 | Aesculap Ag | Surgical suture with anchoring elements |
US20100030220A1 (en) * | 2008-07-31 | 2010-02-04 | Dfine, Inc. | Bone treatment systems and methods |
US9161798B2 (en) * | 2008-02-01 | 2015-10-20 | Dfine, Inc. | Bone treatment systems and methods |
US9445854B2 (en) | 2008-02-01 | 2016-09-20 | Dfine, Inc. | Bone treatment systems and methods |
ES2483996T3 (en) * | 2008-02-28 | 2014-08-08 | Dfine, Inc. | Bone treatment systems and methods |
WO2009151678A1 (en) * | 2008-03-11 | 2009-12-17 | Massachusetts Institute Of Technology | Stimuli-responsive surfaces |
US9259515B2 (en) | 2008-04-10 | 2016-02-16 | Abbott Cardiovascular Systems Inc. | Implantable medical devices fabricated from polyurethanes with grafted radiopaque groups |
US9180416B2 (en) | 2008-04-21 | 2015-11-10 | Dfine, Inc. | System for use in bone cement preparation and delivery |
US20100170521A1 (en) * | 2008-07-24 | 2010-07-08 | Medshape Solutions, Inc. | Method and apparatus for deploying a shape memory polymer |
US8069858B2 (en) * | 2008-07-24 | 2011-12-06 | Medshape Solutions, Inc. | Method and apparatus for deploying a shape memory polymer |
US8430933B2 (en) * | 2008-07-24 | 2013-04-30 | MedShape Inc. | Method and apparatus for deploying a shape memory polymer |
WO2010019716A1 (en) * | 2008-08-13 | 2010-02-18 | Medivas, Llc | Aabb-poly(depsipeptide) biodegradable polymers and methods of use |
US7959598B2 (en) | 2008-08-20 | 2011-06-14 | Asante Solutions, Inc. | Infusion pump systems and methods |
US9277999B2 (en) * | 2009-02-27 | 2016-03-08 | University of Pittsburgh—of the Commonwealth System of Higher Education | Joint bioscaffolds |
DE102009027151A1 (en) * | 2009-06-24 | 2010-12-30 | Gkss-Forschungszentrum Geesthacht Gmbh | Particles with inducible shape change |
US8404484B2 (en) * | 2009-07-15 | 2013-03-26 | Syracuse University | Active cell culture via shape memory |
DE102009060940A1 (en) * | 2009-12-22 | 2011-06-30 | Helmholtz-Zentrum Geesthacht Zentrum für Material- und Küstenforschung GmbH, 21502 | Foam molding with anisotropic shape memory properties, process for its preparation and articles comprising the foam molding |
US8852152B2 (en) | 2011-02-09 | 2014-10-07 | Asante Solutions, Inc. | Infusion pump systems and methods |
US9427493B2 (en) | 2011-03-07 | 2016-08-30 | The Regents Of The University Of Colorado | Shape memory polymer intraocular lenses |
US8454581B2 (en) | 2011-03-16 | 2013-06-04 | Asante Solutions, Inc. | Infusion pump systems and methods |
EP2757964B1 (en) | 2011-05-26 | 2016-05-04 | Cartiva, Inc. | Tapered joint implant and related tools |
US9873765B2 (en) | 2011-06-23 | 2018-01-23 | Dsm Ip Assets, B.V. | Biodegradable polyesteramide copolymers for drug delivery |
CA2839526A1 (en) | 2011-06-23 | 2012-12-27 | Dsm Ip Assets B.V. | Micro- or nanoparticles comprising a biodegradable polyesteramide copolymer for use in the delivery of bioactive agents |
US9406971B2 (en) | 2011-07-01 | 2016-08-02 | GM Global Technology Operations LLC | Shape memory polymer containing composite materials |
US8808230B2 (en) | 2011-09-07 | 2014-08-19 | Asante Solutions, Inc. | Occlusion detection for an infusion pump system |
EP2841010B1 (en) | 2012-04-24 | 2023-08-23 | Harvard Apparatus Regenerative Technology, Inc. | Supports for engineered tissue scaffolds |
US10350072B2 (en) | 2012-05-24 | 2019-07-16 | Cartiva, Inc. | Tooling for creating tapered opening in tissue and related methods |
US8454557B1 (en) | 2012-07-19 | 2013-06-04 | Asante Solutions, Inc. | Infusion pump system and method |
US8454562B1 (en) | 2012-07-20 | 2013-06-04 | Asante Solutions, Inc. | Infusion pump system and method |
US8815054B2 (en) | 2012-10-05 | 2014-08-26 | The Procter & Gamble Company | Methods for making fibrous paper structures utilizing waterborne shape memory polymers |
US9427523B2 (en) | 2012-12-10 | 2016-08-30 | Bigfoot Biomedical, Inc. | Infusion pump system and method |
US20140276536A1 (en) | 2013-03-14 | 2014-09-18 | Asante Solutions, Inc. | Infusion Pump System and Methods |
WO2014110300A1 (en) | 2013-01-09 | 2014-07-17 | Harvard Apparatus Regenerative Technology | Synthetic scaffolds |
US9446186B2 (en) | 2013-03-01 | 2016-09-20 | Bigfoot Biomedical, Inc. | Operating an infusion pump system |
US9457141B2 (en) | 2013-06-03 | 2016-10-04 | Bigfoot Biomedical, Inc. | Infusion pump system and method |
US9446187B2 (en) | 2013-06-03 | 2016-09-20 | Bigfoot Biomedical, Inc. | Infusion pump system and method |
US9744041B2 (en) | 2013-06-20 | 2017-08-29 | Syracuse University | Shape-memory-actuated materials for accelerated healing of orthopedic injuries |
US9561324B2 (en) | 2013-07-19 | 2017-02-07 | Bigfoot Biomedical, Inc. | Infusion pump system and method |
US10633541B2 (en) * | 2013-10-30 | 2020-04-28 | Board of Supervisors of Louisiana State University Agriculture And Mechanical College | Liquid sealant with thermally adaptive properties |
US10569015B2 (en) | 2013-12-02 | 2020-02-25 | Bigfoot Biomedical, Inc. | Infusion pump system and method |
US9629901B2 (en) | 2014-07-01 | 2017-04-25 | Bigfoot Biomedical, Inc. | Glucagon administration system and methods |
US10137246B2 (en) | 2014-08-06 | 2018-11-27 | Bigfoot Biomedical, Inc. | Infusion pump assembly and method |
US9919096B2 (en) | 2014-08-26 | 2018-03-20 | Bigfoot Biomedical, Inc. | Infusion pump system and method |
WO2016064902A1 (en) * | 2014-10-20 | 2016-04-28 | Tara Biosystems, Inc. | Microfabricated tissue scaffolds and methods of making and using the same |
CA2969171C (en) | 2014-12-18 | 2023-12-12 | Dsm Ip Assets B.V. | Drug delivery system for delivery of acid sensitive drugs |
WO2016161025A1 (en) | 2015-03-31 | 2016-10-06 | Cartiva, Inc. | Hydrogel implants with porous materials and methods |
EP3892241A1 (en) | 2015-03-31 | 2021-10-13 | Cartiva, Inc. | Drill bit for carpometacarpal implant |
US9878097B2 (en) | 2015-04-29 | 2018-01-30 | Bigfoot Biomedical, Inc. | Operating an infusion pump system |
EP3374900A1 (en) | 2016-01-05 | 2018-09-19 | Bigfoot Biomedical, Inc. | Operating multi-modal medicine delivery systems |
US10449294B1 (en) | 2016-01-05 | 2019-10-22 | Bigfoot Biomedical, Inc. | Operating an infusion pump system |
USD809134S1 (en) | 2016-03-10 | 2018-01-30 | Bigfoot Biomedical, Inc. | Infusion pump assembly |
CN109789264B (en) | 2016-09-27 | 2021-06-22 | 比格福特生物医药公司 | Drug injection and disease management systems, devices and methods |
USD836769S1 (en) | 2016-12-12 | 2018-12-25 | Bigfoot Biomedical, Inc. | Insulin delivery controller |
US11096624B2 (en) | 2016-12-12 | 2021-08-24 | Bigfoot Biomedical, Inc. | Alarms and alerts for medication delivery devices and systems |
USD839294S1 (en) | 2017-06-16 | 2019-01-29 | Bigfoot Biomedical, Inc. | Display screen with graphical user interface for closed-loop medication delivery |
EP3651647A1 (en) | 2017-07-13 | 2020-05-20 | Bigfoot Biomedical, Inc. | Multi-scale display of blood glucose information |
RU2689574C1 (en) * | 2018-03-01 | 2019-05-28 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский авиационный институт (национальный исследовательский университет)" | Composite material with shape memory effect and method of realizing shape memory effect |
RU2710681C1 (en) * | 2019-02-12 | 2020-01-10 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский авиационный институт (национальный исследовательский университет)" | Metal-polymer composite material with two-way shape memory effect and a method of producing articles therefrom |
CN112870454B (en) * | 2021-02-26 | 2023-09-22 | 江苏大学 | Conductive shape memory polymer device for nerve repair, preparation method and repair method |
Family Cites Families (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4816094A (en) * | 1984-05-01 | 1989-03-28 | Kimberly-Clark Corporation | Method of producing a heat shrinkable elastomer and articles utilizing the elastomer |
US4575373A (en) * | 1984-11-02 | 1986-03-11 | Johnson Don R | Laser adjustable intraocular lens and method of altering lens power |
US5506300A (en) * | 1985-01-04 | 1996-04-09 | Thoratec Laboratories Corporation | Compositions that soften at predetermined temperatures and the method of making same |
KR870700372A (en) * | 1985-01-04 | 1987-12-28 | 원본미기재 | Soft composition at a predetermined temperature and its preparation |
US4596728A (en) * | 1985-02-01 | 1986-06-24 | The Johns Hopkins University | Low temperature heat shrinkable polymer material |
FR2601285B1 (en) * | 1986-07-10 | 1988-11-04 | Pirelli Treficable | HEAT SHRINKABLE SLEEVE COMPRISING MEANS FOR CONTROLLING ITS UNIFORM HEATING, AND METHOD FOR MANUFACTURING SAME. |
US5759830A (en) * | 1986-11-20 | 1998-06-02 | Massachusetts Institute Of Technology | Three-dimensional fibrous scaffold containing attached cells for producing vascularized tissue in vivo |
JP2502132B2 (en) * | 1988-09-30 | 1996-05-29 | 三菱重工業株式会社 | Shape memory polyurethane elastomer molded body |
JPH0739506B2 (en) * | 1988-09-30 | 1995-05-01 | 三菱重工業株式会社 | Shape memory polymer foam |
JPH066342B2 (en) * | 1988-10-14 | 1994-01-26 | 三菱重工業株式会社 | Shape memory film and its use |
JPH0723572B2 (en) * | 1988-10-17 | 1995-03-15 | 三菱重工業株式会社 | Woven fabric with shape memory polymer |
US5189110A (en) * | 1988-12-23 | 1993-02-23 | Asahi Kasei Kogyo Kabushiki Kaisha | Shape memory polymer resin, composition and the shape memorizing molded product thereof |
US5108755A (en) * | 1989-04-27 | 1992-04-28 | Sri International | Biodegradable composites for internal medical use |
JPH0368611A (en) * | 1989-08-08 | 1991-03-25 | Daikin Ind Ltd | Shape memory polymer material |
DE69004245T2 (en) * | 1990-02-23 | 1994-05-11 | Minnesota Mining & Mfg | Semi-thermoplastic molding compound with thermostable shape memory. |
US5665822A (en) * | 1991-10-07 | 1997-09-09 | Landec Corporation | Thermoplastic Elastomers |
US6090072A (en) * | 1992-10-15 | 2000-07-18 | Scimed Life Systems, Inc. | Expandable introducer sheath |
US5418261A (en) * | 1993-01-25 | 1995-05-23 | Imperial Chemical Industries Plc | Polyurethane foams |
US5837682A (en) * | 1996-03-08 | 1998-11-17 | The Children's Medical Center Corporation | Angiostatin fragments and method of use |
DE59508729D1 (en) * | 1994-08-10 | 2000-10-26 | Peter Neuenschwander | Biocompatible block copolymer |
US5765682A (en) * | 1994-10-13 | 1998-06-16 | Menlo Care, Inc. | Restrictive package for expandable or shape memory medical devices and method of preventing premature change of same |
US5776193A (en) * | 1995-10-16 | 1998-07-07 | Orquest, Inc. | Bone grafting matrix |
US5869041A (en) * | 1996-01-12 | 1999-02-09 | The Miriam Hospital | Delivery of bioactive compounds to an organism |
EP0915967A1 (en) * | 1996-05-28 | 1999-05-19 | The Board Of Regents Of The University Of Michigan | Engineering oral tissues |
US5800516A (en) * | 1996-08-08 | 1998-09-01 | Cordis Corporation | Deployable and retrievable shape memory stent/tube and method |
EP0927196B1 (en) * | 1996-09-19 | 2008-11-05 | The Regents Of The University Of Michigan | Polymers containing polysaccharides such as alginates or modified alginates |
US5776162A (en) * | 1997-01-03 | 1998-07-07 | Nitinol Medical Technologies, Inc. | Vessel implantable shape memory appliance with superelastic hinged joint |
JP3732404B2 (en) * | 1998-02-23 | 2006-01-05 | ニーモサイエンス ゲーエムベーハー | Shape memory polymer composition, method of forming a shape memory product, and method of forming a composition that stores a shape |
IL137299A0 (en) * | 1998-02-23 | 2001-07-24 | Massachusetts Inst Technology | Biodegradable shape memory polymers |
DE69822470T2 (en) * | 1998-11-12 | 2005-01-20 | Takiron Co. Ltd. | Biodegradable absorbable shape memory material |
US6299448B1 (en) * | 1999-02-17 | 2001-10-09 | Ivanka J. Zdrahala | Surgical implant system for restoration and repair of body function |
US7615373B2 (en) * | 1999-02-25 | 2009-11-10 | Virginia Commonwealth University Intellectual Property Foundation | Electroprocessed collagen and tissue engineering |
US6767928B1 (en) * | 1999-03-19 | 2004-07-27 | The Regents Of The University Of Michigan | Mineralization and biological modification of biomaterial surfaces |
CN1378445B (en) * | 1999-08-06 | 2013-02-06 | 得克萨斯系统大学评议会 | Drug releasing biodegradable fiber implant |
CA2365376C (en) * | 2000-12-21 | 2006-03-28 | Ethicon, Inc. | Use of reinforced foam implants with enhanced integrity for soft tissue repair and regeneration |
US6656488B2 (en) * | 2001-04-11 | 2003-12-02 | Ethicon Endo-Surgery, Inc. | Bioabsorbable bag containing bioabsorbable materials of different bioabsorption rates for tissue engineering |
US6913762B2 (en) * | 2001-04-25 | 2005-07-05 | Mayo Foundation For Medical Education And Research | Stent having non-woven framework containing cells |
US7311731B2 (en) * | 2001-04-27 | 2007-12-25 | Richard C. Satterfield | Prevention of myocardial infarction induced ventricular expansion and remodeling |
WO2003088818A2 (en) * | 2002-04-18 | 2003-10-30 | Mnemoscience Gmbh | Biodegradable shape memory polymeric sutures |
DE10217350C1 (en) * | 2002-04-18 | 2003-12-18 | Mnemoscience Gmbh | polyesterurethanes |
US20040143221A1 (en) * | 2002-12-27 | 2004-07-22 | Shadduck John H. | Biomedical implant for sustained agent release |
US20040197375A1 (en) * | 2003-04-02 | 2004-10-07 | Alireza Rezania | Composite scaffolds seeded with mammalian cells |
US20050038498A1 (en) * | 2003-04-17 | 2005-02-17 | Nanosys, Inc. | Medical device applications of nanostructured surfaces |
US8226715B2 (en) * | 2003-06-30 | 2012-07-24 | Depuy Mitek, Inc. | Scaffold for connective tissue repair |
US7372879B2 (en) * | 2003-12-05 | 2008-05-13 | Finisar Corporation | Wavelength locker using modulator current and photodetector |
-
2001
- 2001-05-31 WO PCT/EP2001/006210 patent/WO2001091822A1/en active IP Right Grant
- 2001-05-31 AU AU2001263946A patent/AU2001263946A1/en not_active Abandoned
- 2001-05-31 ES ES01938245T patent/ES2230318T3/en not_active Expired - Lifetime
- 2001-05-31 EP EP01938245A patent/EP1284756B1/en not_active Expired - Lifetime
- 2001-05-31 DE DE60105593T patent/DE60105593T2/en not_active Expired - Lifetime
- 2001-05-31 US US10/297,147 patent/US20040110285A1/en not_active Abandoned
- 2001-05-31 CA CA002410637A patent/CA2410637C/en not_active Expired - Fee Related
- 2001-05-31 AT AT01938245T patent/ATE275986T1/en active
-
2008
- 2008-04-10 US US12/081,104 patent/US20080305545A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DE60105593T2 (en) | 2005-02-03 |
WO2001091822A1 (en) | 2001-12-06 |
EP1284756B1 (en) | 2004-09-15 |
EP1284756A1 (en) | 2003-02-26 |
ATE275986T1 (en) | 2004-10-15 |
CA2410637C (en) | 2007-04-10 |
US20040110285A1 (en) | 2004-06-10 |
AU2001263946A1 (en) | 2001-12-11 |
US20080305545A1 (en) | 2008-12-11 |
DE60105593D1 (en) | 2004-10-21 |
ES2230318T3 (en) | 2005-05-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA2410637A1 (en) | Shape memory polymers seeded with dissociated cells for tissue engineering | |
CA2126087A1 (en) | Composite membranes for the guided regeneration of tissues | |
CA2126085A1 (en) | Non-woven fabric material comprising hyaluronic acid derivatives | |
CA2207757A1 (en) | Breast tissue engineering | |
AU4349700A (en) | Rapid gelling biocompatible polymer composition | |
CA2307567A1 (en) | Polymer matrix/cell construct for bladder reconstruction | |
CA2267244A1 (en) | Methods for treating urinary incontinence in mammals | |
WO2006050493A3 (en) | Biodegradable implant for intertransverse process fusion | |
CA2296374A1 (en) | Semi-interpenetrating polymer networks | |
CA2238011A1 (en) | A biologic material comprising an efficient culture of bone marrow stem cells partially or completely differentiated into connective tissue cells and a three-dimensional biocompatible and biodegradable matrix consisting of a hyaluronic acid derivative | |
HU9503132D0 (en) | Polymer composition, absorbent material composition, their production and their use | |
EP0767819A4 (en) | pH-MODIFIED BIOCOMPATIBLE MONOMER AND POLYMER COMPOSITIONS | |
CA2394672A1 (en) | Biodegradable polymer composition | |
AU3870995A (en) | Biodegradable polymers, process for their preparation and their use for producing biodegradable moulded bodies | |
EP1362565A4 (en) | Artificial pyramid | |
WO2001013819A3 (en) | A method of making biodegradable polymeric implants | |
AU3871395A (en) | Biodegradable polymers, process for their preparation and their use for producing biodegradable moulded bodies | |
CA2311631A1 (en) | Net shaped and crosslinked articulating bearing surface for an orthopaedic implant | |
WO2003028782A1 (en) | Composite material for tissue regeneration | |
DK1085917T3 (en) | Biomaterials containing hyaluronic acid derivatives in the form of three-dimensional structures free of cellular components or products thereof for in vivo regeneration of tissue cells | |
AU8021201A (en) | Monomer composition, polymer obtained therefrom, and ocular lens | |
AU2001280212A1 (en) | Monomer composition, polymer obtained therefrom, and ocular lens | |
GB9902976D0 (en) | Composite | |
CA2246615A1 (en) | Biodegradable polymer networks for use in orthopedic and dental applications | |
HUP0002491A3 (en) | Polymer composition, process for producing thereof and its use |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |
Effective date: 20130531 |