CA2331468A1 - Pyrazolo[1,5-a]pyrimidine derivatives - Google Patents

Pyrazolo[1,5-a]pyrimidine derivatives Download PDF

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Publication number
CA2331468A1
CA2331468A1 CA002331468A CA2331468A CA2331468A1 CA 2331468 A1 CA2331468 A1 CA 2331468A1 CA 002331468 A CA002331468 A CA 002331468A CA 2331468 A CA2331468 A CA 2331468A CA 2331468 A1 CA2331468 A1 CA 2331468A1
Authority
CA
Canada
Prior art keywords
derivatives
pyrazolo
pyrimidine derivatives
useful
lower alkoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002331468A
Other languages
English (en)
French (fr)
Other versions
CA2331468C (en
Inventor
Takashi Okumura
Yasuo Shoji
Tadao Shibutani
Tsuneo Yasuda
Takeshi Iwamoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Factory, Inc.
Takashi Okumura
Yasuo Shoji
Tadao Shibutani
Tsuneo Yasuda
Takeshi Iwamoto
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Factory, Inc., Takashi Okumura, Yasuo Shoji, Tadao Shibutani, Tsuneo Yasuda, Takeshi Iwamoto filed Critical Otsuka Pharmaceutical Factory, Inc.
Publication of CA2331468A1 publication Critical patent/CA2331468A1/en
Application granted granted Critical
Publication of CA2331468C publication Critical patent/CA2331468C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
CA002331468A 1998-05-19 1999-05-17 Pyrazolo[1,5-a]pyrimidine derivatives Expired - Fee Related CA2331468C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP10/136960 1998-05-19
JP13696098 1998-05-19
PCT/JP1999/002572 WO1999059998A1 (fr) 1998-05-19 1999-05-17 DERIVES DE PYRAZOLO[1,5-a]PYRIMIDINE

Publications (2)

Publication Number Publication Date
CA2331468A1 true CA2331468A1 (en) 1999-11-25
CA2331468C CA2331468C (en) 2005-06-28

Family

ID=15187527

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002331468A Expired - Fee Related CA2331468C (en) 1998-05-19 1999-05-17 Pyrazolo[1,5-a]pyrimidine derivatives

Country Status (11)

Country Link
US (1) US6372749B1 (it)
EP (1) EP1081149B1 (it)
JP (1) JP4058587B2 (it)
KR (1) KR100391398B1 (it)
CN (1) CN1117093C (it)
AT (1) ATE236166T1 (it)
AU (1) AU751337B2 (it)
CA (1) CA2331468C (it)
DE (1) DE69906511T2 (it)
NO (1) NO317303B1 (it)
WO (1) WO1999059998A1 (it)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100836207B1 (ko) * 2001-01-18 2008-06-09 웰리켐 바이오 테크 인크. 면역 질환 치료용의 신규한 1,2-디페닐에텐 유도체
HUP0400891A2 (en) * 2004-04-29 2006-04-28 Janos Szolcsanyi 7h-pyrrolo[2,3-d]pyrimidine derivatives, their pharmaceutically acceptable salts, pharmaceutical compositions containing them and process for the production of the compounds
US20150018566A1 (en) * 2011-08-25 2015-01-15 The Provost, Fellows, Foundation Scholars, & the Other Members of Board, of The College of the Holy Tubulin binding agents

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2585462B2 (ja) * 1989-10-25 1997-02-26 株式会社大塚製薬工場 ピラゾロ[1,5―a]ピリミジン誘導体
JPH07309872A (ja) * 1994-03-24 1995-11-28 Otsuka Pharmaceut Factory Inc 縮環ピリミジン誘導体及び鎮痛剤
JP3163413B2 (ja) * 1994-06-21 2001-05-08 株式会社大塚製薬工場 鎮痛剤
JP3163412B2 (ja) * 1994-06-21 2001-05-08 株式会社大塚製薬工場 ピラゾロ〔1,5−a〕ピリミジン誘導体
JP3252189B2 (ja) * 1994-06-21 2002-01-28 株式会社大塚製薬工場 ピラゾロ〔1,5−a〕ピリミジン誘導体
EP0820997B1 (en) * 1995-04-10 2001-07-25 Otsuka Pharmaceutical Factory, Inc. PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVES
JP3204877B2 (ja) 1995-06-08 2001-09-04 株式会社エルモ社 資料提示装置
US5843951A (en) * 1995-09-28 1998-12-01 Otsuka Pharmaceutical Factory Inc. Analgesic composition of pyrazolo(1,5-A) pyrimidines
JPH10101671A (ja) 1996-08-08 1998-04-21 Otsuka Pharmaceut Factory Inc 一酸化窒素合成酵素阻害剤
JPH10114774A (ja) * 1996-08-20 1998-05-06 Otsuka Pharmaceut Factory Inc 一酸化窒素合成酵素阻害剤

Also Published As

Publication number Publication date
DE69906511D1 (de) 2003-05-08
EP1081149B1 (en) 2003-04-02
DE69906511T2 (de) 2004-01-29
NO20005820D0 (no) 2000-11-17
KR100391398B1 (ko) 2003-07-12
CN1299362A (zh) 2001-06-13
NO20005820L (no) 2000-11-17
ATE236166T1 (de) 2003-04-15
CN1117093C (zh) 2003-08-06
CA2331468C (en) 2005-06-28
US6372749B1 (en) 2002-04-16
AU3732099A (en) 1999-12-06
AU751337B2 (en) 2002-08-15
JP4058587B2 (ja) 2008-03-12
EP1081149A1 (en) 2001-03-07
KR20010034871A (ko) 2001-04-25
NO317303B1 (no) 2004-10-04
WO1999059998A1 (fr) 1999-11-25
EP1081149A4 (en) 2001-12-19

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