CA2212490C - Deployable and retrievable shape memory stent/tube and method - Google Patents

Deployable and retrievable shape memory stent/tube and method Download PDF

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Publication number
CA2212490C
CA2212490C CA002212490A CA2212490A CA2212490C CA 2212490 C CA2212490 C CA 2212490C CA 002212490 A CA002212490 A CA 002212490A CA 2212490 A CA2212490 A CA 2212490A CA 2212490 C CA2212490 C CA 2212490C
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CA
Canada
Prior art keywords
tubular member
stent
balloon
diameter
treatment site
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002212490A
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French (fr)
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CA2212490A1 (en
Inventor
Michael J. Fine
Kenneth S. Solovay
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Cordis Corp
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Cordis Corp
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Filing date
Publication date
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Publication of CA2212490A1 publication Critical patent/CA2212490A1/en
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Publication of CA2212490C publication Critical patent/CA2212490C/en
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95Instruments specially adapted for placement or removal of stents or stent-grafts
    • A61F2/958Inflatable balloons for placing stents or stent-grafts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0014Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol
    • A61F2210/0023Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol operated at different temperatures whilst inside or touching the human body, heated or cooled by external energy source or cold supply

Abstract

A method for the deployment and retrieval of a tubular member. The method is achieved by first introducing a tubular member having a first diameter to a preselected treatment site, wherein said tubular member exhibits shape memory characteristics. The tubular member is then expanded to a second diameter at the treatment site and deployed at the treatment site. After a predetermined time, the tubular member is retrieved from the treatment site by causing the tubular member to return to its first diameter and withdrawing the tubular member from the treatment site. A tubular member with shape memory characteristics for use in accordance with the method is also provided.

Description

BACKGROUND OF THE INVENTION
1. Field of the Invention The invention relates to methods and apparatuses for deploying and retrieving tubular members within a patient. More particularly, the invention relates to methods and apparatuses for deploying and retrieving shape memory stents with a thermodynamic dilatation balloon catheter.
2. Description of the Prior Art Stents have become an integral part of the current war with heart disease and are commonly used in conjunction with percutaneoue transluminal coronary angioplasty. Specifically, coronary angioplasty utilizes an expandable balloon positioned at the distal end of a catheter to open coronary arteries. In use, the balloon of a dilatation balloon catheter is positioned at a treatment site where the balloon is expanded. When the balloon is properly positioned at the affected coronary artery, the expansion of the balloon expands the narrowed lumen of the coronary artery. Expansion of the lumen is achieved by stretching, cracking, breaking, and tearing of the vessel wall and the arterial plaque thereby causing the expansion of the vessel lumen.
While the initial expansion caused by the balloon may be successful, the vessel elastic recoil, intimal flaps, thrombus formation and smooth muscle fibroproliferation often cause the S:~A&WFILES~APPL~COR-002 ' vessel lumen to substantial narrow after the lumen has been expanded by convention coronary angioplasty. Stents have, therefore, been employed in combination with the coronary angioplasty procedure to maintain the expansion caused by the balloon. The stents utilized in this procedure are generally plastic or metallic, and are deployed at the treatment site by expanding a narrow cylindrical stent until the stent engages the inner wall of the lumen. While the term stent is currently used throughout this patent disclosure to denote a short cylindrical member open at both ends for insertion in a blood vessel following balloon angioplasty to prevent restenosis, terms other than stent, such as graft prosthesis, arterial endoprosthesis, intraluminal graft and intravascular mechanical support may be and are frequently used instead of the term stent to convey the same meaning.
The application of stents in combination with convention coronary angioplasty has achieved great success in retarding the expanded vessel's natural tendency to narrow after expansion by coronary angioplasty. However, most stents are designed to remain at the treatment site, even after the desired result of maintaining the expanded vessel has been achieved. This is problematic since it is often medically desirable to remove the stent after it has performed its function or if the stent does not function as desired. In such cases, it is necessary to S:\A6WFILES\APPL\COR-002 surgically remove the stent through complicated techniques that place the patient at risk.
The problems associated with the removal of stents, and other medical devices, is addressed in U.S. Patent No. 4,950,258, to Kawai et al. The patent discloses the use of biodegradable stents manufactured from shape memory materials. The patent suggests that the need for surgical removal of medical devices is obviated by manufacturing the device from a biodegradable materials. Similarly, PCT Publication No. WO 93/06792 discloses the use of. biodegradable stents.
Despite the advantage of not requiring surgery to remove biodegradable devices, the physician looses control of the device once it is positioned within the patient's body, since the degradation rate of the device is predetermined and cannot normally be varied once it is properly positioned. The is exceptionally troublesome in some coronary angioplasty procedures where a physician might desire to evaluate the distended vessel before deciding to remove the deployed stent.
In addition to coronary angioplasty procedures, stents are widely used in medical procedures where it is necessary to maintain a vessel or organ in an open position. As with coronary angioplasty, it is often necessary to remove the stent and the prior art, unfortunately, fails to provide a method or apparatus facilitating the simple and convenient removal of a stent once the stent has been deployed.
S:~ABHFILES~APPL~COR-002 A need, therefore, continues to exist for a technique whereby a stent can be readily retrieved and deployed. The present invention provides a method and apparatus for the efficient deployment and retrieval of a stent.
S:~A&WFILES~APPL~COR-002 SUMMARY OF THE INVENTION
In accordance with one aspect of the present invention, there is provided a method for the deployment and retrieval of a tubu:Lar member. The method is effected by first introducing a tubular member, having a first diameter, to a preselected treatment ~:ite, wherein said tubular member exhibits shape memory characteristics. The tubular member is then expanded to a second diameter at the treatment site. and deployed at the treatment site. After a predetermined time, the tubular member is retrieved from the treatment site by causing the tubular member to return to its diameter and withdrawing the tubular member from the treatment site.
The tubular member may be a stmt.
In one embodiment of the invention, the steps of introducing, expanding, and retrieving are facilitated by using a dilation balloon catheter.
The step of introducing may include the steps of positioning the tubular member about a dilation balloon catheter, which may be a thermodynamic dilation balloon catheter, and inserting the dilation balloon catheter to the treatment site.

The step of expanding may include the step of expanding the dilation balloon catheter until the tubular member reaches a desired second diameter.
The step of retrieving may include positioning the dilation balloon catheter ar the treatment site, expanding the dilation balloon catheter, which may be a thermodynamic dilation balloon catheter, heating the tubular member, deflating the dilation balloon catheter while the tubular member returns to its fir~:t diameter, and withdrawing the dilation balloon catheter and the tubular member.
The step of expanding may include expanding the dilation balloon catheter while the tubular member reaches a desired second diameter, preferably by heating the tubular member and then expanding the dilation balloon catheter until t:he tubular member reaches a desired second diameter..
According to another aspect of the present invention, there is provided a deployable and retrievable tubular member, comprising:
a cylindrical body constructed from a shape memory material, the body having a memory shape adapted for positioning about an introducing device wherein the memory shape is substantially smaller than the treatment site where the tubular member may be expanded for treatment;
wherein the tubular member is deployed at a treatment site by positioning the tubular member at the treatment site, expanding the tubular member to a second diameter and removing the introducing device from the treatment site, and the tubular member is subsequently retrieved by heating they tubular member to a temperature causing the tubular member to return to the memory shape and removing the tubular member.

Other advantages of the present invention will become apparent from the following detailed description when viewed in conjunction with the accompanying drawings, which set forth certain embodiments of the invention.

BRIEF DESCRIPTION OF THE DRAWINGS
Figures 1-4 are cross-sectional views sequentially showing the deployment of a stent within a vessel.
Figures 5-a are cross-sectional views sequentially showing the retrieval of a stmt within a vessel.
S:\Ag~FILES\APPL\COR-002 DESCRIPTION OF THE PREFERRED EMBODIMENT
The detailed embodiment of the present invention is disclosed herein. It should be understood, however, that the disclosed embodiment is merely exemplary of the invention, which may be embodied in various forms. Therefore, the details disclosed herein are not to be interpreted as limited, but merely as the basis for the claims and as a basis for teaching one skilled in the art how to make and/or use the invention.
With reference to Figures 1 through 8, a method for the deployment and retrieval of a stent is disclosed. A stent 10 having a first diameter is positioned on a dilatation balloon catheter 12.
The stent 10 is constructed from a shape memory plastic. As a result, the stent 10 is manufactured with a first memorized shape and may be manipulated to take other shapes, but will return to the memorized shape when it is heated to a critical transition temperature. The term "transition temperature" refers to the temperature at which the shape memory material becomes flexible and attempts to return to its memorized shaped. At this temperature the stent is flexible and will return to the memorized shape unless force is applied to the stent maintaining the stent in a second shape until the temperature of the stem moves below the transition temperature.
Shape memory items are generally manufactured and used. in the following manner. First, an item is manufactured with a 1 O 5:\A&WFILES\APPL\COR-002 first shape. If it is desirable to memorize the first shape, the item is heated to a predetermined temperature dictated by the material construction of the item, held at the predetermined temperature, and ultimately cooled to memorize the first shape.
Once the memorizing process is completed, the plastic may be heated to an extent making the plastic malleable and permitting deformation of the item, reformed into a second shape, and cooled to retain the second shape. The temperature to which the item must be heated before it can be molded may be the transition temperature. If this.is the case, the item must be held in the second shape until the temperature of the item falls below the transition temperature to retain the shape. However, when the item is again heated to its transition temperature, the item will return to the first memorized shape due to the memory characteristics of the material. The materials and techniques used in the construction of shape memory stents are well known as exemplified by U.S. Patent No. 4,950,258, to Kawai et al., entitled "PLASTIC MOLDED ARTICLES WITH SHAPE MEMORY PROPERTIES".
In accordance with the present invention, the stent 10 has an open tubular shape and is manufactured with a first memorized shape having a first diameter. The first diameter should be slightly larger than deflated balloon 14 of the dilatation balloon catheter 12, but smaller than the vessel 16 into which the stent is intended to be delivered. While the disclosed stent 10 is tubular shaped, the stent could be manufactured in a 1 1 S:\A&WFILES\APPL\COR-002 variety of shapes and structures without departing from the spirit of the present invention. Similarly, the stent may be manufactured from a wide variety of shape memory materials, including plastics, metal alloys and/or biodegradable materials, while maintaining the spirit of the present invention. In addition, the stent may be manufactured to provide for drug delivery at the treatment site. The only limiting factor with regard to the shape, structure and material construction of the stent is the stent must exhibit strength and size characteristics permitting it to be used for desired applications.
With regard to the dilatation balloon chtheter 12, it is preferably a thermodynamic balloon catheter capable of applying heat to the stent positioned on the balloon. Preferably, the balloon catheter embodied in U.S. Patent No. 5,417,689, to Michael J. Fine, entitled "THERMAL BALLOON CATHETER AND METHOD"
and issued on May 23, 1995, is used in performing the instant invention. It should, however, be understood that other heated balloon catheters could be used, without departing from the spirit of the present invention so long as the catheters are able to apply the controlled heat and pressure needed to accomplish the claimed method. It might also be advisable to utilize a dilatation balloon catheter permitting the perfusion of blood while the balloon is inflated.
After the stent 10 is properly positioned about the balloon 14 located at the distal end 18 of the dilatation balloon 1 2 S:~ABWFILES~APPL~COR-002 catheter 12, the balloon 14 is slightly expanded to secure the stent 10 at the distal end 18 of the dilatation balloon catheter 12. It should be understood that the stent could be manufactured with a first memorized shape such that the stent securely fits about the balloon without the need for inflating the balloon to secure the balloon at the distal end of the catheter. Similarly, it might be possible to crimp the stent about the balloon to securely position the stent at the distal end of the catheter.
With reference to Figure 1, the catheter 12 and stent 10 are introduced within the patient's body and positioned at a predetermined treatment site 20 in the vessel 16. This is accomplished using conventional techniques which are well documented in the art and very familiar to those of ordinary skill in the art. The balloon l4 of the dilatation balloon catheter 12 is then heated, applying heat to the stent 10, and pressure is applied to the balloon 14. When the temperature of the stent 10 reaches or exceeds the transition temperature, the stent 10 becomes flexible and expands as the pressure inflates the balloon 14 (see Figure 2). The exact temperature will depend upon the material construction of the stent, the location of the treatment site, and other variables associated with the specific details of the procedure being performed. However, the transition temperature must be higher than the body temperature of the patient.
The balloon 14 is inflated to its maximum diameter and the 1 3 S:\A&WFILES\APPL\COR-002 stent 10 similarly expands to a second diameter at the treatment site. The balloon 14 and stent 10 are expanded in a deliberate manner to prevent damage to the stent 10. Specifically, as pressure is applied to the balloon 14, the temperature in the balloon 14 drops slightly and must be raised to maintain the temperature of the stent 10 above the transition temperature.
Therefore, heat is applied to raise the balloon temperature each time additional incremental pressure is applied to the balloon 14. Once the balloon temperature is heated to its desired temperature and the stent 10 expands, the procedure of expanding and heating is repeated until the 'balloon 14 is inflated to its maximum diameter and the stent 10 expands to its second diameter.
The second diameter should be sufficiently large to securely position the stent 10 within the treatment site 20 in a manner similar to that used in conventional stent delivery systems.
While the balloon 14 maintains the stent 10 in its second diameter, the balloon 14 is rapidly cooled to a temperature well below the transition temperature to cool the stent 10 so that it does not return to its first memory shape when the balloon is deflated. Once the stent 10 is cooled below its transition temperature, the balloon 14 is deflated and withdrawn from the treatment site 20 to deploy the stent 10 at the treatment site (see Figs. 3 and 4). The deployed stent l0 then functions to maintain the treatment site, for example, a coronary artery, open 1 4 5:\ABWFILES\APPL\COR-002 in a desirable manner. It should, however, be understood that, to the extent possible using shape memory materials, the stent might not need to be heated. to the transition temperature before it can be expanded by the balloon.
The stent 10 then remains within the patient at the treatment site 20 until the responsible physician determines that it is desirably to remove the stent 10. At this time, referring to Fig. S, the balloon 14 of the dilatation balloon catheter 12 is once again positioned at the treatment site 20 with the balloon 14 concentrically positioned relative to the previously deployed stent 10. The balloon 14 of the dilatation balloon catheter 12 is then fully expanded until it contacts the inner surface 22 of the deployed stent 10 and the balloon 14 is heated to apply heat to the stent 10. Heat is applied until the stent 10 reaches or exceeds its transition temperature (see Fig. 6).
Once the stent 10 reaches its critical transition temperature it will begin to return to its first memorized shape, that is, its first diameter.
With reference to Figure 7, the balloon 14 is then slowly deflated while heat continues to be applied to the stent 10 and the balloon 14 of the balloon dilatation catheter 12.
Specifically, the balloon 14 is deflated in a manner permitting the stent 10 to remain in contact with the balloon 14 such that the stent 10 is maintained at, or above, its transition temperature to permit the stent 10 to fully return to its first 1 S S:\A&WFILES\APPL\COR-002 memorized shape. After the balloon 14 is deflated and the stent has returned to its first memorized shape, the dilatation balloon catheter 12 and the stent 10 are removed 24 from the patient (see Fig. e).
The present invention provides for the efficient deployment and retrieval of a shape memory stent in a previously unknown manner. In fact, the present invention permits the a stent to be retrieved without the need for undesirable surgical procedures.
The method and apparatus may be used with a wide variety of applications for which stents, and other tubular members, have found wide acceptance, including, but not limited to, restenosis stents used in coronary angioplasty, permanent stents, temporary stents, vessel aneurysm repair tubes, and bail out devices stabilizing patients until permanent vascular repair can be performed.
While the preferred embodiment has been shown and described, it will be understood that there is no intent to limit the invention by such disclosure, but rather, is intended to cover all modifications and alternate constructions falling within the spirit and scope of the invention as defined in the appended claims.
I 6 S:\ABWFILES\APPL\COR-002

Claims (3)

1. A deployable and retrievable tubular member, comprising:
a cylindrical body constructed from a shape memory material, the body having a memory shape adapted for positioning about an introducing device wherein the memory shape has a first diameter which is substantially smaller than the diameter of a treatment site where the tubular member may be expanded for treatment;
wherein the tubular member is deployable at the treatment site by positioning the tubular member at the treatment site, by heating the tubular member to a temperature at which the tubular member is malleable, by expanding the tubular member to a second diameter and by removing the introducing device from the treatment site and wherein the tubular member is adapted to be subsequently retrieved by heating the tubular member to, or above, a transition temperature of the shape memory material to cause the tubular member to begin to return to the memory shape by continuously heating the tubular member at, or above, the transition temperature until the tubular member returns to its first diameter and removing the tubular member;
wherein the shape memory material is a shape memory plastic material.
2. The tubular member according to claim 1, wherein the tubular member is a stent.
3. The tubular member according to claim 1 or claim 2 in combination with an introducer device, wherein the introducer device is a dilatation balloon catheter and the original first diameter is slightly larger than the diameter of the unexpanded balloon of the dilatation balloon catheter.
CA002212490A 1996-08-08 1997-08-01 Deployable and retrievable shape memory stent/tube and method Expired - Lifetime CA2212490C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/693,708 1996-08-08
US08/693,708 US5800516A (en) 1996-08-08 1996-08-08 Deployable and retrievable shape memory stent/tube and method

Publications (2)

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CA2212490A1 CA2212490A1 (en) 1998-02-08
CA2212490C true CA2212490C (en) 2006-10-17

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US (1) US5800516A (en)
EP (1) EP0823245B1 (en)
CA (1) CA2212490C (en)
DE (1) DE69729694T2 (en)

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