CA2166352A1 - Absorbable block copolymers and surgical articles fabricated therefrom - Google Patents

Absorbable block copolymers and surgical articles fabricated therefrom

Info

Publication number
CA2166352A1
CA2166352A1 CA002166352A CA2166352A CA2166352A1 CA 2166352 A1 CA2166352 A1 CA 2166352A1 CA 002166352 A CA002166352 A CA 002166352A CA 2166352 A CA2166352 A CA 2166352A CA 2166352 A1 CA2166352 A1 CA 2166352A1
Authority
CA
Canada
Prior art keywords
block copolymers
surgical articles
copolymers
fabricated therefrom
articles fabricated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002166352A
Other languages
French (fr)
Other versions
CA2166352C (en
Inventor
Mark S. Roby
Cheng-Kung Liu
Steven L. Bennett
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
United States Surgical Corp
Original Assignee
United States Surgical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by United States Surgical Corp filed Critical United States Surgical Corp
Publication of CA2166352A1 publication Critical patent/CA2166352A1/en
Application granted granted Critical
Publication of CA2166352C publication Critical patent/CA2166352C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/66—Polyesters containing oxygen in the form of ether groups
    • C08G63/664—Polyesters containing oxygen in the form of ether groups derived from hydroxy carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/06—Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
    • A61B17/06166—Sutures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/06—At least partially resorbable materials
    • A61L17/10—At least partially resorbable materials containing macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/06—At least partially resorbable materials
    • A61L17/10—At least partially resorbable materials containing macromolecular materials
    • A61L17/12—Homopolymers or copolymers of glycolic acid or lactic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/64—Polyesters containing both carboxylic ester groups and carbonate groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00004—(bio)absorbable, (bio)resorbable, resorptive

Abstract

Block copolymers have one of the block made from hard phase forming monomers and another block made from soft phase forming monomers copolymerized with randomly intermingled units of other soft phase forming monomers. Particularly useful copolymers are initiated with a polyalkylene oxide initiator. The copolymers are useful in forming surgical articles, including both monofilament and multifilament sutures.
CA002166352A 1994-12-29 1995-12-29 Absorbable block copolymers and surgical articles fabricated therefrom Expired - Fee Related CA2166352C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/366,127 US5522841A (en) 1993-05-27 1994-12-29 Absorbable block copolymers and surgical articles fabricated therefrom
US08/366,127 1994-12-29

Publications (2)

Publication Number Publication Date
CA2166352A1 true CA2166352A1 (en) 1996-06-30
CA2166352C CA2166352C (en) 2008-02-19

Family

ID=23441775

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002166352A Expired - Fee Related CA2166352C (en) 1994-12-29 1995-12-29 Absorbable block copolymers and surgical articles fabricated therefrom

Country Status (5)

Country Link
US (1) US5522841A (en)
EP (1) EP0719811B1 (en)
CA (1) CA2166352C (en)
DE (1) DE69530363T2 (en)
ES (1) ES2191694T3 (en)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69428994T2 (en) * 1993-05-27 2002-06-20 Cognis Corp POLYMER THICKENER FOR AQUEOUS COMPOSITIONS
US6315788B1 (en) 1994-02-10 2001-11-13 United States Surgical Corporation Composite materials and surgical articles made therefrom
US5747637A (en) * 1995-09-07 1998-05-05 Mitsui Toatsu Chemicals, Inc. Bioabsorbable polymer and process for preparing the same
DE19641335A1 (en) * 1996-10-08 1998-04-09 Inst Textil & Faserforschung Triblock terpolymer, its use in surgical sutures and manufacturing methods
ZA978537B (en) 1996-09-23 1998-05-12 Focal Inc Polymerizable biodegradable polymers including carbonate or dioxanone linkages.
DE19641334A1 (en) * 1996-10-08 1998-04-09 Inst Textil & Faserforschung Triblock terpolymer, its use in medical products and manufacturing processes
US6191236B1 (en) 1996-10-11 2001-02-20 United States Surgical Corporation Bioabsorbable suture and method of its manufacture
US5912076A (en) 1996-12-31 1999-06-15 Kimberly-Clark Worldwide, Inc. Blends of polyethylene and peo having inverse phase morphology and method of making the blends
EP0980273A1 (en) * 1997-04-16 2000-02-23 White Spot AG Biodegradable osteosynthesis implant
US6007565A (en) * 1997-09-05 1999-12-28 United States Surgical Absorbable block copolymers and surgical articles fabricated therefrom
US5976694A (en) 1997-10-03 1999-11-02 Kimberly-Clark Worldwide, Inc. Water-sensitive compositions for improved processability
US6120788A (en) * 1997-10-16 2000-09-19 Bioamide, Inc. Bioabsorbable triglycolic acid poly(ester-amide)s
US6277927B1 (en) 1997-11-26 2001-08-21 United States Surgical Corporation Absorbable block copolymers and surgical articles fabricated therefrom
US6511748B1 (en) 1998-01-06 2003-01-28 Aderans Research Institute, Inc. Bioabsorbable fibers and reinforced composites produced therefrom
US6165202A (en) * 1998-07-06 2000-12-26 United States Surgical Corporation Absorbable polymers and surgical articles fabricated therefrom
US6228920B1 (en) 1998-07-10 2001-05-08 Kimberly-Clark Woldwide, Inc. Compositions and process for making water soluble polyethylene oxide films with enhanced toughness and improved melt rheology and tear resistance
US6235869B1 (en) 1998-10-20 2001-05-22 United States Surgical Corporation Absorbable polymers and surgical articles fabricated therefrom
US6579570B1 (en) 2000-05-04 2003-06-17 Kimberly-Clark Worldwide, Inc. Ion-sensitive, water-dispersible polymers, a method of making same and items using same
US6423804B1 (en) 1998-12-31 2002-07-23 Kimberly-Clark Worldwide, Inc. Ion-sensitive hard water dispersible polymers and applications therefor
US6713414B1 (en) 2000-05-04 2004-03-30 Kimberly-Clark Worldwide, Inc. Ion-sensitive, water-dispersible polymers, a method of making same and items using same
US6884427B1 (en) * 1999-02-08 2005-04-26 Aderans Research Institute, Inc. Filamentary means for introducing agents into tissue of a living host
JP2001054563A (en) * 1999-07-12 2001-02-27 Isotis Bv Suture
KR20010010393A (en) * 1999-07-20 2001-02-05 김윤 Biodegradable Block Copolymer of Hydrophobic and Hydrophilic Polymers, and Composition for Drug Delivery Comprising Same
US6444761B1 (en) 1999-12-28 2002-09-03 Kimberly-Clark Worldwide, Inc. Water-soluble adhesive compositions
WO2001066018A1 (en) 2000-03-03 2001-09-13 C. R. Bard, Inc. Endoscopic tissue apposition device with multiple suction ports
US6815502B1 (en) 2000-05-04 2004-11-09 Kimberly-Clark Worldwide, Inc. Ion-sensitive, water-dispersable polymers, a method of making same and items using same
US6429261B1 (en) 2000-05-04 2002-08-06 Kimberly-Clark Worldwide, Inc. Ion-sensitive, water-dispersible polymers, a method of making same and items using same
US6444214B1 (en) 2000-05-04 2002-09-03 Kimberly-Clark Worldwide, Inc. Ion-sensitive, water-dispersible polymers, a method of making same and items using same
US6548592B1 (en) 2000-05-04 2003-04-15 Kimberly-Clark Worldwide, Inc. Ion-sensitive, water-dispersible polymers, a method of making same and items using same
US6835678B2 (en) 2000-05-04 2004-12-28 Kimberly-Clark Worldwide, Inc. Ion sensitive, water-dispersible fabrics, a method of making same and items using same
US6599848B1 (en) 2000-05-04 2003-07-29 Kimberly-Clark Worldwide, Inc. Ion-sensitive, water-dispersible polymers, a method of making same and items using same
US6683143B1 (en) 2000-05-04 2004-01-27 Kimberly Clark Worldwide, Inc. Ion-sensitive, water-dispersible polymers, a method of making same and items using same
US6653406B1 (en) 2000-05-04 2003-11-25 Kimberly Clark Worldwide, Inc. Ion-sensitive, water-dispersible polymers, a method of making same and items using same
AU2001279209B2 (en) * 2000-08-08 2006-08-24 Aderans Research Institute, Inc. Scaffolds for tissue engineered hair
US6752831B2 (en) 2000-12-08 2004-06-22 Osteotech, Inc. Biocompatible osteogenic band for repair of spinal disorders
EP1341484B1 (en) * 2000-12-08 2009-05-06 Osteotech, Inc. Implant for orthopedic applications
US6586529B2 (en) 2001-02-01 2003-07-01 Kimberly-Clark Worldwide, Inc. Water-dispersible polymers, a method of making same and items using same
US6828014B2 (en) 2001-03-22 2004-12-07 Kimberly-Clark Worldwide, Inc. Water-dispersible, cationic polymers, a method of making same and items using same
US8740987B2 (en) * 2001-06-04 2014-06-03 Warsaw Orthopedic, Inc. Tissue-derived mesh for orthopedic regeneration
US20040068284A1 (en) * 2002-01-29 2004-04-08 Barrows Thomas H. Method for stimulating hair growth and kit for carrying out said method
US20030236319A1 (en) * 2002-06-25 2003-12-25 Hye-Sung Yoon Block copolymers for surgical articles
US7148315B2 (en) * 2002-10-23 2006-12-12 Ethicon, Inc. Monomer addition techniques to control manufacturing of bioabsorbable copolymers
JP2007519492A (en) * 2004-01-30 2007-07-19 オステオテック，インコーポレイテッド Stacked implant for spinal fusion
US8337545B2 (en) 2004-02-09 2012-12-25 Cook Medical Technologies Llc Woven implantable device
US7597885B2 (en) * 2004-03-26 2009-10-06 Aderans Research Institute, Inc. Tissue engineered biomimetic hair follicle graft
EP1737391A2 (en) * 2004-04-13 2007-01-03 Cook Incorporated Implantable frame with variable compliance
AR050212A1 (en) * 2004-08-13 2006-10-04 Aderans Res Inst Inc ORGANOGENESIS FROM DISCELLED CELLS
US8197534B2 (en) 2005-03-31 2012-06-12 Cook Medical Technologies Llc Valve device with inflatable chamber
US20060276882A1 (en) * 2005-04-11 2006-12-07 Cook Incorporated Medical device including remodelable material attached to frame
WO2007062386A2 (en) * 2005-11-22 2007-05-31 Aderans Research Institute, Inc. Hair follicle graft from tissue engineered skin
US20070122387A1 (en) * 2005-11-22 2007-05-31 Aderans Research Institute, Inc. Hair grafts derived from plucked hair
US8952123B1 (en) * 2006-08-02 2015-02-10 Abbott Cardiovascular Systems Inc. Dioxanone-based copolymers for implantable devices
US7985537B2 (en) * 2007-06-12 2011-07-26 Aderans Research Institute, Inc. Methods for determining the hair follicle inductive properties of a composition
US20130005829A1 (en) 2011-06-30 2013-01-03 Advanced Technologies And Regenerative Medicine, Llc. Segmented, epsilon-Caprolactone-Rich, Poly(epsilon-Caprolactone-co-p-Dioxanone) Copolymers for Medical Applications and Devices Therefrom
US10940167B2 (en) 2012-02-10 2021-03-09 Cvdevices, Llc Methods and uses of biological tissues for various stent and other medical applications
US20130236499A1 (en) 2012-03-12 2013-09-12 Sasa Andjelic Segmented, Semicrystalline Poly(Lactide-co-epsilon-Caprolactone) Absorbable Copolymers
AU2014214700B2 (en) 2013-02-11 2018-01-18 Cook Medical Technologies Llc Expandable support frame and medical device
US9978529B2 (en) 2016-01-11 2018-05-22 Pacesetter, Inc. Oxide on edges of metal anode foils
US10090112B2 (en) 2016-01-15 2018-10-02 Pacesetter, Inc. Use of etch resist masked anode frame for facilitation of laser cutting, particle and leakage current reduction
US10300165B2 (en) 2016-01-20 2019-05-28 Ethicon, Inc. Segmented, p-Dioxanone-Rich, Poly(p-Dioxanone-co-epsilon-Caprolactone) copolymers for medical applications and devices made therefrom
US9969030B2 (en) 2016-05-12 2018-05-15 Pacesetter, Inc. Laser drilling of metal foils for assembly in an electrolytic capacitor
US9852849B2 (en) 2016-05-27 2017-12-26 Pacesetter, Inc. Using etch resist patterns and formation for facilitation of laser cutting, particle and leakage current reduction
EP3628698A1 (en) 2018-09-26 2020-04-01 Covidien LP Biodegradable triblock copolymers and implantable medical devices made therefrom

Family Cites Families (84)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2683136A (en) * 1950-10-25 1954-07-06 Du Pont Copolymers of hydroxyacetic acid with other alcohol acids
US2703316A (en) * 1951-06-05 1955-03-01 Du Pont Polymers of high melting lactide
US2668162A (en) * 1952-03-20 1954-02-02 Du Pont Preparation of high molecular weight polyhydroxyacetic ester
US2758987A (en) * 1952-06-05 1956-08-14 Du Pont Optically active homopolymers containing but one antipodal species of an alpha-monohydroxy monocarboxylic acid
NL99836C (en) * 1954-10-20
US3225766A (en) * 1962-03-26 1965-12-28 Grace W R & Co Method of making absorbable surgical sutures from poly beta hydroxy acids
NL294714A (en) * 1963-06-28
US3463158A (en) * 1963-10-31 1969-08-26 American Cyanamid Co Polyglycolic acid prosthetic devices
US3297033A (en) * 1963-10-31 1967-01-10 American Cyanamid Co Surgical sutures
US3620218A (en) * 1963-10-31 1971-11-16 American Cyanamid Co Cylindrical prosthetic devices of polyglycolic acid
US3268487A (en) * 1963-12-23 1966-08-23 Shell Oil Co Process for polymerization of lactides
US3442871A (en) * 1966-05-04 1969-05-06 American Cyanamid Co Process for polymerizing a glycolide
US3422181A (en) * 1966-05-23 1969-01-14 American Cyanamid Co Method for heat setting of stretch oriented polyglycolic acid filament
US3468853A (en) * 1966-06-15 1969-09-23 American Cyanamid Co Process of polymerizing a glycolide
GB1198261A (en) * 1966-08-23 1970-07-08 Laporte Chemical Oxidation of Aromatic Compounds
US3597449A (en) * 1967-11-16 1971-08-03 American Cyanamid Co Stable glycolide and lactide composition
US3772420A (en) * 1968-12-23 1973-11-13 American Cyanamid Co Method for improving the in-vivo strength of polyglycolic acid
US3626948A (en) * 1968-12-23 1971-12-14 American Cyanamid Co Absorbable polyglycolic acid suture of enhanced in-vivo strength retention
US3565869A (en) * 1968-12-23 1971-02-23 American Cyanamid Co Extrudable and stretchable polyglycolic acid and process for preparing same
BE758156R (en) * 1970-05-13 1971-04-28 Ethicon Inc ABSORBABLE SUTURE ELEMENT AND ITS
US3797499A (en) * 1970-05-13 1974-03-19 Ethicon Inc Polylactide fabric graphs for surgical implantation
GB1332505A (en) * 1970-10-16 1973-10-03 Ethicon Inc Sutures and other surgical aids
US3846382A (en) * 1971-02-25 1974-11-05 American Cyanamid Co Sterile medical dusting powder
US3781349A (en) * 1971-02-25 1973-12-25 American Cyanamid Co Preparation of polyglycolic acid in finely divided form
US3987937A (en) * 1971-05-06 1976-10-26 Eppco Powder feeder and methods for transporting particulate material
US3878284A (en) * 1971-08-12 1975-04-15 American Cyanamid Co Processes for making shaped articles such as filaments or films from solutions of polyglycolic acid
US3733919A (en) * 1971-09-20 1973-05-22 Adjustable eccentric bearing mountings background
US3736646A (en) * 1971-10-18 1973-06-05 American Cyanamid Co Method of attaching surgical needles to multifilament polyglycolic acid absorbable sutures
US3867190A (en) * 1971-10-18 1975-02-18 American Cyanamid Co Reducing capillarity of polyglycolic acid sutures
US3784585A (en) * 1971-10-21 1974-01-08 American Cyanamid Co Water-degradable resins containing recurring,contiguous,polymerized glycolide units and process for preparing same
US3839297A (en) * 1971-11-22 1974-10-01 Ethicon Inc Use of stannous octoate catalyst in the manufacture of l(-)lactide-glycolide copolymer sutures
US3792010A (en) * 1972-03-27 1974-02-12 Ethicon Inc Plasticized polyester sutures
US3982543A (en) * 1973-04-24 1976-09-28 American Cyanamid Company Reducing capillarity of polyglycolic acid sutures
US4033938A (en) * 1974-01-21 1977-07-05 American Cyanamid Company Polymers of unsymmetrically substituted 1,4-dioxane-2,5-diones
GB1414600A (en) * 1974-02-08 1975-11-19 Ethicon Inc Plasticised polyester sutures
US3902497A (en) * 1974-03-25 1975-09-02 American Cyanamid Co Body absorbable sponge and method of making
US3937223A (en) * 1974-04-19 1976-02-10 American Cyanamid Company Compacted surgical hemostatic felt
US4057537A (en) * 1975-01-28 1977-11-08 Gulf Oil Corporation Copolymers of L-(-)-lactide and epsilon caprolactone
US4045418A (en) * 1975-01-28 1977-08-30 Gulf Oil Corporation Copolymers of D,L-lactide and epsilon caprolactone
US4060089A (en) * 1975-09-03 1977-11-29 United States Surgical Corporation Surgical fastening method and device therefor
US4052988A (en) * 1976-01-12 1977-10-11 Ethicon, Inc. Synthetic absorbable surgical devices of poly-dioxanone
US4300565A (en) * 1977-05-23 1981-11-17 American Cyanamid Company Synthetic polyester surgical articles
US4243775A (en) * 1978-11-13 1981-01-06 American Cyanamid Company Synthetic polyester surgical articles
US4137921A (en) * 1977-06-24 1979-02-06 Ethicon, Inc. Addition copolymers of lactide and glycolide and method of preparation
US4246904A (en) * 1979-01-29 1981-01-27 American Cyanamid Company Surgical suture derived from segmented polyether-ester block copolymers
FR2439003A1 (en) * 1978-10-20 1980-05-16 Anvar NEW OSTEOSYNTHESIS PARTS, THEIR PREPARATION AND THEIR APPLICATION
US4275813A (en) * 1979-06-04 1981-06-30 United States Surgical Corporation Coherent surgical staple array
US4273920A (en) * 1979-09-12 1981-06-16 Eli Lilly And Company Polymerization process and product
JPS5827548A (en) * 1981-07-30 1983-02-18 エチコン・インコ−ポレ−テツド Annealed polydioxane surgical instrument and production thereof
EP0092918B1 (en) * 1982-04-22 1988-10-19 Imperial Chemical Industries Plc Continuous release formulations
US4429080A (en) * 1982-07-01 1984-01-31 American Cyanamid Company Synthetic copolymer surgical articles and method of manufacturing the same
US4438253A (en) * 1982-11-12 1984-03-20 American Cyanamid Company Poly(glycolic acid)/poly(alkylene glycol) block copolymers and method of manufacturing the same
US4452973A (en) * 1982-11-12 1984-06-05 American Cyanamid Company Poly(glycolic acid)/poly(oxyethylene) triblock copolymers and method of manufacturing the same
GB8416234D0 (en) * 1984-06-26 1984-08-01 Ici Plc Biodegradable amphipathic copolymers
US4643191A (en) * 1985-11-29 1987-02-17 Ethicon, Inc. Crystalline copolymers of p-dioxanone and lactide and surgical devices made therefrom
US4653497A (en) * 1985-11-29 1987-03-31 Ethicon, Inc. Crystalline p-dioxanone/glycolide copolymers and surgical devices made therefrom
US4739773A (en) * 1986-05-09 1988-04-26 Deere & Company Feeding arrangement for an axial flow rotary separator
US4744365A (en) * 1986-07-17 1988-05-17 United States Surgical Corporation Two-phase compositions for absorbable surgical devices
US4857602A (en) * 1986-09-05 1989-08-15 American Cyanamid Company Bioabsorbable surgical suture coating
US4716203A (en) * 1986-09-05 1987-12-29 American Cyanamid Company Diblock and triblock copolymers
US4705820A (en) * 1986-09-05 1987-11-10 American Cyanamid Company Surgical suture coating
US4788979A (en) * 1986-09-23 1988-12-06 American Cyanamid Company Bioabsorbable coating for a surgical article
ES2040719T3 (en) * 1986-09-23 1993-11-01 American Cyanamid Company BIO-ABSORBABLE COATING FOR A SURGICAL ARTICLE.
US4896802A (en) * 1987-06-30 1990-01-30 Kabushikigaisha Nanami Machine for producing bundled plastic tape products such as pompons
US5145945A (en) * 1987-12-17 1992-09-08 Allied-Signal Inc. Homopolymers and copolymers having recurring carbonate units
US5120802A (en) * 1987-12-17 1992-06-09 Allied-Signal Inc. Polycarbonate-based block copolymers and devices
US4916207A (en) * 1987-12-17 1990-04-10 Allied-Signal, Inc. Polycarbonate homopolymer-based fiber compositions and method of melt-spinning same and device
US4916193A (en) * 1987-12-17 1990-04-10 Allied-Signal Inc. Medical devices fabricated totally or in part from copolymers of recurring units derived from cyclic carbonates and lactides
US5185408A (en) * 1987-12-17 1993-02-09 Allied-Signal Inc. Medical devices fabricated totally or in part from copolymers of recurring units derived from cyclic carbonates and lactides
US5152781A (en) * 1987-12-17 1992-10-06 Allied-Signal Inc. Medical devices fabricated from homopolymers and copolymers having recurring carbonate units
US4891263A (en) * 1987-12-17 1990-01-02 Allied-Signal Inc. Polycarbonate random copolymer-based fiber compositions and method of melt-spinning same and device
US4920203A (en) * 1987-12-17 1990-04-24 Allied-Signal Inc. Medical devices fabricated from homopolymers and copolymers having recurring carbonate units
US5066772A (en) * 1987-12-17 1991-11-19 Allied-Signal Inc. Medical devices fabricated totally or in part from copolymers of recurring units derived from cyclic carbonates and lactides
US4838267A (en) * 1988-02-12 1989-06-13 Ethicon, Inc. Glycolide/p-dioxanone block copolymers
US5007923A (en) * 1990-01-31 1991-04-16 Ethicon, Inc. Crystalline copolyesters of amorphous (lactide/glycolide) and p-dioxanone
US5133739A (en) * 1990-02-06 1992-07-28 Ethicon, Inc. Segmented copolymers of ε-caprolactone and glycolide
US5037950A (en) * 1990-02-09 1991-08-06 Ethicon, Inc. Bioabsorbable copolymers of polyalkylene carbonate/RHO-dioxanone for sutures and coatings
US5019094A (en) * 1990-05-09 1991-05-28 Ethicon, Inc. Crystalline copolymers of p-dioxanone and poly(alkylene oxides)
US5080665A (en) * 1990-07-06 1992-01-14 American Cyanamid Company Deformable, absorbable surgical device
US5252701A (en) * 1990-07-06 1993-10-12 American Cyanamid Company Segmented absorbable copolymer
US5225520A (en) * 1991-04-17 1993-07-06 United States Surgical Corporation Absorbable composition
US5236444A (en) * 1992-10-27 1993-08-17 United States Surgical Corporation Absorbable polymers and surgical articles made therefrom
US5322925A (en) * 1992-10-30 1994-06-21 United States Surgical Corporation Absorbable block copolymers and surgical articles made therefrom
US5403347A (en) * 1993-05-27 1995-04-04 United States Surgical Corporation Absorbable block copolymers and surgical articles fabricated therefrom

Also Published As

Publication number Publication date
ES2191694T3 (en) 2003-09-16
EP0719811B1 (en) 2003-04-16
EP0719811A3 (en) 1996-11-13
US5522841A (en) 1996-06-04
DE69530363D1 (en) 2003-05-22
DE69530363T2 (en) 2003-12-04
CA2166352C (en) 2008-02-19
EP0719811A2 (en) 1996-07-03

Similar Documents

Publication Publication Date Title
CA2166352A1 (en) Absorbable block copolymers and surgical articles fabricated therefrom
CA2122670A1 (en) Absorbable block copolymers and surgical articles fabricated therefrom
CA2109451A1 (en) Absorbable block copolymers and surgical articles made therefrom
CA2195384A1 (en) Absorbable polymer blends and surgical articles fabricated therefrom
CA2337133A1 (en) Absorbable polymers and surgical articles fabricated therefrom
CA2238387A1 (en) Absorbable mixture and coatings for surgical articles fabricated therefrom
CA2046192A1 (en) Deformable surgical device
CA2123647A1 (en) Bioabsorbable copolymer and coating composition containing same
CA2311477A1 (en) Absorbable block copolymers and surgical articles fabricated therefrom
CA2035243A1 (en) Copolymers of .epsilon.-caprolactone, glycolide and glycolic acid for suture coating
ES8500626A1 (en) Synthetic copolymer surgical articles and method of manufacturing the same.
AU627343B2 (en) Random copolymers of p-dioxanone, lactide and/or glycolide as coating polymers for surgical filaments
GB9814609D0 (en) Polymers
CA2496410A1 (en) Compositions and methods for coating food cans
WO2002035984A3 (en) Leak and tear resistant grafts
CA2205422A1 (en) Absorbable polyalkylene diglycolates
CA2279300A1 (en) Polyesteramides from cyclic monomers and surgical articles made therefrom
CA2160202A1 (en) Absorbable polymer and surgical articles fabricated therefrom
CA2224013A1 (en) Surgeon's gloves from neoprene copolymers
IE832331L (en) Ethylene-propylene copolymer sutures.
AU3170489A (en) Bioabsorbable coating for a surgical article
CA2035592A1 (en) Segmented copolymers of .epsilon.-caprolactone and glycolide
CA2158420A1 (en) Absorbable polymer and surgical articles fabricated therefrom
EP1125589B8 (en) Surgical suture
CA2222098A1 (en) Enhanced toughening and improved processability of polyolefins and polyolefin copolymers with low molecular weight additives

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20141229

MKLA Lapsed

Effective date: 20141229