Thiol-based redox homeostasis and signallingFrancisco J. Cejudo, Andreas J. Meyer, Jean-Philippe Reichheld, Nicolas Rouhier, Jose A. Traverso In contrast to the situation in heterotrophic organisms, plant genomes code for a significantly larger number of oxidoreductases such as thioredoxins (TRXs) and glutaredoxins (GRXs). These proteins provide a biochemical mechanism that allows the rapid and reversible activation or deactivation of protein functions in response to changing environmental conditions, as oxidative conditions caused by excessive photosynthesis. Indeed, owing to the fact that cysteines are sensitive to oxidation, TRXs and GRXs play an essential role in controlling the redox state of protein thiol groups. These redox-dependent post-translational modifications have proven to be critical for many cellular functions constituting regulatory, signalling or protective mechanisms. |
Contents
Thiolbased redox homeostasis and signaling | 5 |
something old something new | 8 |
a oneforall redoxsignaling system in plants | 29 |
Overexpression of plastidial thioredoxins f and m differentially alters photosynthetic activity and response to oxidative stress in tobacco plants | 39 |
a thioredoxinmediated metabolic switch? | 52 |
Operation of transthylakoid thiolmetabolizing pathways in photosynthesis | 61 |
balancing toxic and signaling activities of hydrogen peroxide | 67 |
Thiolbased redox control of enzymes involved in the tetrapyrrole biosynthesis pathway in plants | 73 |
Kinetic analysis of the interactions between plant thioredoxin and target proteins | 129 |
redox posttranslational modifications and moonlighting properties | 137 |
biochemical basis for the definition of two subclasses | 155 |
Glutaredoxins are essential for stress adaptation in the cyanobacterium Synechocystis sp PCC 6803 | 169 |
Utility of Synechocystis sp PCC 6803 glutaredoxin A as a platform to study highresolution mutagenesis of proteins | 180 |
how is glutathione oxidized in plants? | 190 |
A phenomics approach to the analysis of the influence of glutathione on leaf area and abiotic stress tolerance in arabidopsis thaliana | 203 |
Thiolbased redox signaling in the nitrogenfixing symbiosis | 212 |
Redoxdependent functional switching of plant proteins accompanying with their structural changes | 84 |
Overexpression of chloroplast nadphdependent thioredoxin reductase in arabidopsis enhances leaf growth and elucidates in vivo function of reductas... | 91 |
Dissecting the integrative antioxidant and redox systems in plant mitochondria Effect of stress and Snitrosylation | 109 |
new insights and perspectives | 222 |