Advances in Peptide and Peptidomimetic Design Inspiring Basic Science and Drug Discovery: A Themed Issue Honoring Professor Victor J. Hruby on the Occasion of His 80th BirthdayHenry I. Mosberg, Carrie Haskell-Luevano, Tomi K. Sawyer Advances in Peptide and Peptidomimetic Design Inspiring Basic Science and Drug Discovery is a book dedicated to Prof. Victor J. Hruby on the occasion of his 80th birthday. This book includes twenty contributions from authors representing diverse multidisciplinary fields of scientific expertise, and is focused on the extraordinary potential of peptides and peptidomimetics as a surging therapeutic modality and as tools for basic research and technology development. |
Common terms and phrases
activity added addition agonist amino acid analogs analysis antimicrobial assay authors binding binding affinities bond calcd calculated cancer cells charged Chem chemistry chromatography combined compared complex compound concentration conformation conjugate containing coupling CrossRef derivatives described determined drug effects efficacy enhanced Figure Fmoc function further HPLC human hydrophobic important improved increased inhibition inhibitors interactions kinase ligands lytic MC4R Mdm2 measured membrane methods mixture mmol molecular molecules novel observed obtained peptide performed position potency potential prediction prepared present previously properties protein PubMed purified reaction receptor reported residues resin respectively sample selectivity sequence showed shown side signaling solid solution specific stability stapled stirred structure substitution synthesis Table therapeutic treatment values washed yield