Targets, Tracers and Translation – Novel Radiopharmaceuticals Boost Nuclear MedicineGerald Reischl This is the fourth Special Issue in Pharmaceuticals within the last six years dealing with aspects of radiopharmaceutical sciences. It demonstrates the significant interest and increasing relevance to ameliorate nuclear medicine imaging with PET or SPECT, and also radiotherapeutical procedures.Numerous targets and mechanisms have been identified and have been under investigation over the previous years, covering many fields of medical and clinical research. This development is well illustrated by the articles in the present issue, including 13 original research papers and one review, covering a broad range of actual research topics in the field of radiopharmaceutical sciences. |
Common terms and phrases
acid activity added affinity agent analogs analysis animal antibody application authors binding biodistribution blood brain calculated cancer carcinoma cells Chem chemistry chromatography clinical compared compounds concentration conjugates corresponding CrossRef derivatives described determined developed doses effect evaluation experiments expression Figure further Germany glutamate GRPR HBPLs higher HPLC human hypoxia improved increased incubated inhibitors injection internalization labeling levels ligands mass measured method mice mixture molecular Nucl nucleoside observed obtained patients peptide performed PET imaging phase precursor prepared prostate protein PubMed purification radioactivity radiochemical radiolabeled radioligands radiopharmaceutical radiotracer ratio reaction recently receptor reference respectively samples selectivity serum showed solution specific stability standard structures studies synthesis targeting temperature therapy tissue tracer transporters tumor tumor uptake University uptake values vitro vivo yield