Toxicity of Pesticides on Health and Environment

Front Cover
Robin Mesnage, Gilles-Eric Seralini
Frontiers Media SA, Dec 7, 2018

 Public policy is regularly shaken by health crises or unexpected discoveries; future directions in toxicology assessment are therefore urgently needed. 

Convergent evidences suggest endocrine or nervous disrupting effects of pesticides, as well as effects on wildlife and the environment. These effects are amplified by the use of surfactants and/or combinations of different active principles. 

The usual concepts of regulatory toxicology are challenged by endocrine, nervous or immune disruption, or epigenetic effects. Indeed, most pollutants alter cell-cell communication systems to promote chronic diseases. They may accumulate in the food chain. Mixtures effects with other pollutants may change their bioavailability and their toxicity. The lack of scientific knowledge in these matters has large costs for public health. 

This Research Topic focuses on the toxic effects of pesticides associated with large scale cultivation of genetically modified (GM) plants.

 

Selected pages

Contents

Toxicity of Pesticides on Health and Environment
4
The Urgent Need for a New Concept in Agriculture
6
Too Much of a Good Thing?
14
Organosilicone Surfactants May Not Be Safe
28
Estrogenic and antiandrogenic endocrine disrupting chemicals and their impact on the male reproductive system
36
Inflammatory Effects of the Plant Protection Product Stifenia FEN560 on Vertebrates
39
Ecological Surprises?
48
Specificity and Combinatorial Effects of Bacillus Thuringiensis Cry Toxins in the Context of GMO Environmental Risk Assessment
56
Weaknesses in Study Design
74
Reregistration Challenges of Glyphosate in the European Union
79
Enhancements Needed in GE Crop and Food Regulation in the US
114
Scientists and Civil Society Must Move Together toward a New Science
120
Back Cover
123
Copyright

Common terms and phrases

active ingredient adjuvants agricultural agrochemical AMPA animals apoptosis application aquatic atrazine Bacillus thuringiensis Benachour Benbrook Bøhn Bt toxins cadherin carcinogenic cell lines chemical combinatorial effects commercial compounds contamination Cry toxins Cry1Ab Cuhra cytotoxicity ecological EFSA Entomol Environ environmental European Food Safety evaluation exposure fenugreek Food Chem Food Safety Authority formulations GBHs gene genetically modified global glyphosate and AMPA glyphosate concentrations glyphosate residues glyphosate-based herbicides glyphosate-tolerant GM crops GM food GM plants herbicide Hilbeck honey bee human IARC increased indicated induced insect insecticides interactions King’s College London larvae maize Mesnage mg/kg mg/ml mode of action monarch butterfly Monsanto MRLs neonicotinoid non-target organisms PBMC pesticides POEA pollination potential production proteins rats receptors regulation regulatory reported residue levels resistance risk assessment Roundup samples Science scientific Séralini soybean species spray adjuvants Stifenia studies surface water surfactants synergistic target pest tested toxicity Toxicol transgenic weed zebrafish

Bibliographic information

TitleToxicity of Pesticides on Health and Environment
Frontiers Research Topics
EditorsRobin Mesnage, Gilles-Eric Seralini
PublisherFrontiers Media SA, 2018
ISBN2889456447, 9782889456444
  
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