Disposable Bioprocessing SystemsWritten by a researcher with experience designing, establishing, and validating biological manufacturing facilities worldwide, this is the first comprehensive introduction to disposable systems for biological drug manufacturing. It reviews the current state of the industry; tackles questions about safety, costs, regulations, and waste disposal; and guides readers to choose disposable components that meet their needs. This practical manual covers disposable containers, mixing systems, bioreactors, connectors and transfers, controls and sensors, downstream processing systems, filling and finishing systems, and filters. The author also shares his predictions for the future, calling disposable bioprocessing technology a "game changer." |
Contents
1 The Bioprocessing IndustryAn Introduction | 1 |
2 Safety of Disposable Systems | 23 |
3 Containers | 45 |
4 Mixing Systems | 53 |
5 Disposable Bioreactors | 61 |
6 Connectors and Transfers | 121 |
7 Controls | 137 |
8 Downstream Processing | 149 |
9 Filling and Finishing Systems | 169 |
10 Filtration | 179 |
11 Regulatory Compliance | 191 |
12 Environmental Concerns | 203 |
13 Epilogue | 237 |
| 253 | |
| 291 | |
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Common terms and phrases
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